Natrialba magadii (DSM 3394, ATCC 43099, CCM 3739)

Name: Natrialba magadii (DSM 3394, ATCC 43099, CCM 3739)
Creator: BacDive
License: http://creativecommons.org/licenses/by/4.0/

BacDive ID 5960

Type strain

Strain Designation MS3

Culture col. no. DSM 3394 ATCC 43099 CCM 3739 NCMB 2190 MS3 6 more

NCBI tax ID(s) 547559 13769

Special Collections DSMZ JCM CIP

Links

Natrialba magadii MS3 is a mesophilic, Gram-negative, motile prokaryote of the family Natrialbaceae.

Gram-negative motile rod-shaped mesophilic genome sequence 16S sequence

Name and taxonomic classification

SI-ID 41647

ATCC 43099,NCMB 2190,CIP 104546,CCM 3739,DSM 3394,JCM 8861,NCIMB 2190,IAM 13178,NBRC 102185,CGMCC 1.1966

@ref 20215

Last LPSN update 2025-12-16 09:48:11

Domain Methanobacteriati

Phylum Methanobacteriota

Class Halobacteria

Order Halobacteriales

Family Natrialbaceae

Genus Natrialba

Species Natrialba magadii

Full scientific name Natrialba magadii (Tindall et al. 1984) Kamekura et al. 1997

Synonyms (1)

Natronobacterium magadii

Morphology

Cell morphology

@ref	Gram stain	Cell shape	Motility
120747	negative	rod-shaped
125438

Culture and growth conditions

Culture medium

@ref	Name	Medium link	Composition
1375	NATRONOBACTERIA MEDIUM (DSMZ Medium 371)	Medium recipe at MediaDive	Name: NATRONOBACTERIA MEDIUM (DSMZ Medium 371) Composition: NaCl 200.0 g/l Agar 20.0 g/l Casamino acids 5.0 g/l Yeast extract 5.0 g/l Na2CO3 5.0 g/l Na2-glutamate 1.0 g/l KH2PO4 1.0 g/l KCl 1.0 g/l NH4Cl 1.0 g/l MgSO4 x 7 H2O 0.24 g/l CaSO4 x 2 H2O 0.17 g/l HCl 0.0025 g/l FeCl2 x 4 H2O 0.0015 g/l CoCl2 x 6 H2O 0.00019 g/l MnCl2 x 4 H2O 0.0001 g/l ZnCl2 7e-05 g/l Na2MoO4 x 2 H2O 3.6e-05 g/l NiCl2 x 6 H2O 2.4e-05 g/l H3BO3 6e-06 g/l CuCl2 x 2 H2O 2e-06 g/l Distilled water
38508	MEDIUM 136 - for Natronococcus occultus, Natrialba magadii and Halorubrum vacuolatum		Solution 2 - M0437 (600.000 ml);Solution 1 - M0437 (400.000 ml)
120747	CIP Medium 136	Medium recipe at CIP

Culture temp

@ref	Growth	Type	Temperature (°C)	Range
1375	positive	growth	37	mesophilic
38508	positive	growth	37	mesophilic
67770	positive	growth	37	mesophilic
120747	positive	growth	30-45
120747	negative	growth	10

Physiology and metabolism

Oxygen tolerance

@ref	Oxygen tolerance	Confidence
125439	aerobe	95.1

Observation

67770

Observationquinones: MK-8, MK-8(H₂)

Metabolite utilization

@ref	Chebi-ID	Metabolite	Utilization activity	Kind of utilization tested
120747	4853 ChEBI	esculin	-	hydrolysis
120747	17632 ChEBI	nitrate	-	reduction
120747	16301 ChEBI	nitrite	-	reduction

Metabolite production

@ref	Chebi-ID	Metabolite	Production
120747	35581 ChEBI	indole

Enzymes

@ref	Value	Activity	Ec
68382	acid phosphatase	-	3.1.3.2	from API zym
120747	alcohol dehydrogenase	-	1.1.1.1
68382	alkaline phosphatase	-	3.1.3.1	from API zym
68382	alpha-chymotrypsin	-	3.4.21.1	from API zym
68382	alpha-fucosidase	-	3.2.1.51	from API zym
68382	alpha-galactosidase	-	3.2.1.22	from API zym
68382	alpha-glucosidase	-	3.2.1.20	from API zym
68382	alpha-mannosidase	-	3.2.1.24	from API zym
68382	beta-galactosidase	-	3.2.1.23	from API zym
120747	beta-galactosidase	+	3.2.1.23
68382	beta-glucosidase	-	3.2.1.21	from API zym
68382	beta-glucuronidase	-	3.2.1.31	from API zym
120747	catalase	+	1.11.1.6
68382	cystine arylamidase	-	3.4.11.3	from API zym
68382	esterase (C 4)	+		from API zym
68382	esterase lipase (C 8)	+		from API zym
120747	gelatinase	-
68382	leucine arylamidase	+	3.4.11.1	from API zym
68382	lipase (C 14)	-		from API zym
120747	lysine decarboxylase	-	4.1.1.18
68382	N-acetyl-beta-glucosaminidase	-	3.2.1.52	from API zym
68382	naphthol-AS-BI-phosphohydrolase	-		from API zym
120747	ornithine decarboxylase	-	4.1.1.17
120747	oxidase	+
68382	trypsin	-	3.4.21.4	from API zym
120747	urease	-	3.5.1.5
68382	valine arylamidase	-		from API zym

Pathway annotation

Computationally determined by

@ref	pathway	enzyme coverage	annotated reactions
66794	gluconeogenesis	100	8 of 8
66794	adipate degradation	100	2 of 2
66794	palmitate biosynthesis	100	22 of 22
66794	phenylacetate degradation (aerobic)	100	5 of 5
66794	6-hydroxymethyl-dihydropterin diphosphate biosynthesis	100	8 of 8
66794	lipoate biosynthesis	100	5 of 5
66794	vitamin K metabolism	100	5 of 5
66794	L-lactaldehyde degradation	100	3 of 3
66794	coenzyme A metabolism	100	4 of 4
66794	isoleucine metabolism	100	8 of 8
66794	anapleurotic synthesis of oxalacetate	100	1 of 1
66794	ethanol fermentation	100	2 of 2
66794	folate polyglutamylation	100	1 of 1
66794	suberin monomers biosynthesis	100	2 of 2
66794	cis-vaccenate biosynthesis	100	2 of 2
66794	creatinine degradation	100	5 of 5
66794	UDP-GlcNAc biosynthesis	100	3 of 3
66794	methylglyoxal degradation	100	5 of 5
66794	glutamate and glutamine metabolism	92.86	26 of 28
66794	vitamin B1 metabolism	92.31	12 of 13
66794	threonine metabolism	90	9 of 10
66794	propionate fermentation	90	9 of 10
66794	chorismate metabolism	88.89	8 of 9
66794	CO2 fixation in Crenarchaeota	88.89	8 of 9
66794	C4 and CAM-carbon fixation	87.5	7 of 8
66794	alanine metabolism	86.21	25 of 29
66794	citric acid cycle	85.71	12 of 14
66794	propanol degradation	85.71	6 of 7
66794	ubiquinone biosynthesis	85.71	6 of 7
66794	phenylalanine metabolism	84.62	11 of 13
66794	pantothenate biosynthesis	83.33	5 of 6
66794	glycolysis	82.35	14 of 17
66794	pyrimidine metabolism	82.22	37 of 45
66794	factor 420 biosynthesis	80	4 of 5
66794	Entner Doudoroff pathway	80	8 of 10
66794	flavin biosynthesis	80	12 of 15
66794	ethylmalonyl-CoA pathway	80	4 of 5
66794	glycogen metabolism	80	4 of 5
66794	tetrahydrofolate metabolism	78.57	11 of 14
66794	NAD metabolism	77.78	14 of 18
66794	valine metabolism	77.78	7 of 9
66794	aspartate and asparagine metabolism	77.78	7 of 9
66794	molybdenum cofactor biosynthesis	77.78	7 of 9
66794	leucine metabolism	76.92	10 of 13
66794	purine metabolism	76.6	72 of 94
66794	acetate fermentation	75	3 of 4
66794	glycogen biosynthesis	75	3 of 4
66794	biotin biosynthesis	75	3 of 4
66794	lipid metabolism	74.19	23 of 31
66794	methionine metabolism	73.08	19 of 26
66794	pentose phosphate pathway	72.73	8 of 11
66794	photosynthesis	71.43	10 of 14
66794	cardiolipin biosynthesis	71.43	5 of 7
66794	lysine metabolism	69.05	29 of 42
66794	histidine metabolism	68.97	20 of 29
66794	octane oxidation	66.67	2 of 3
66794	enterobactin biosynthesis	66.67	2 of 3
66794	acetoin degradation	66.67	2 of 3
66794	arginine metabolism	66.67	16 of 24
66794	serine metabolism	66.67	6 of 9
66794	4-hydroxymandelate degradation	66.67	6 of 9
66794	formaldehyde oxidation	66.67	2 of 3
66794	cyanate degradation	66.67	2 of 3
66794	selenocysteine biosynthesis	66.67	4 of 6
66794	glycolate and glyoxylate degradation	66.67	4 of 6
66794	d-mannose degradation	66.67	6 of 9
66794	methane metabolism	66.67	2 of 3
66794	non-pathway related	65.79	25 of 38
66794	tryptophan metabolism	65.79	25 of 38
66794	heme metabolism	64.29	9 of 14
66794	glutathione metabolism	64.29	9 of 14
66794	tyrosine metabolism	64.29	9 of 14
66794	proline metabolism	63.64	7 of 11
66794	urea cycle	61.54	8 of 13
66794	phosphatidylethanolamine bioynthesis	61.54	8 of 13
66794	cysteine metabolism	61.11	11 of 18
66794	3-chlorocatechol degradation	60	3 of 5
66794	starch degradation	60	6 of 10
66794	gallate degradation	60	3 of 5
66794	4-hydroxyphenylacetate degradation	60	6 of 10
66794	degradation of aromatic, nitrogen containing compounds	58.33	7 of 12
66794	sulfate reduction	53.85	7 of 13
66794	degradation of sugar acids	52	13 of 25
66794	oxidative phosphorylation	50.55	46 of 91
66794	degradation of sugar alcohols	50	8 of 16
66794	butanoate fermentation	50	2 of 4
66794	ribulose monophosphate pathway	50	1 of 2
66794	resorcinol degradation	50	1 of 2
66794	ketogluconate metabolism	50	4 of 8
66794	kanosamine biosynthesis II	50	1 of 2
66794	androgen and estrogen metabolism	50	8 of 16
66794	myo-inositol biosynthesis	50	5 of 10
66794	aminopropanol phosphate biosynthesis	50	1 of 2
66794	glycine metabolism	50	5 of 10
66794	phenylmercury acetate degradation	50	1 of 2
66794	lactate fermentation	50	2 of 4
66794	quinate degradation	50	1 of 2
66794	CDP-diacylglycerol biosynthesis	50	1 of 2
66794	metabolism of disaccharids	45.45	5 of 11
66794	carotenoid biosynthesis	45.45	10 of 22
66794	arachidonic acid metabolism	44.44	8 of 18
66794	degradation of pentoses	42.86	12 of 28
66794	mevalonate metabolism	42.86	3 of 7
66794	isoprenoid biosynthesis	42.31	11 of 26
66794	vitamin B12 metabolism	41.18	14 of 34
66794	coenzyme M biosynthesis	40	4 of 10
66794	bacilysin biosynthesis	40	2 of 5
66794	metabolism of amino sugars and derivatives	40	2 of 5
66794	glycine betaine biosynthesis	40	2 of 5
66794	arachidonate biosynthesis	40	2 of 5
66794	phenol degradation	40	8 of 20
66794	dTDPLrhamnose biosynthesis	37.5	3 of 8
66794	cholesterol biosynthesis	36.36	4 of 11
66794	bile acid biosynthesis, neutral pathway	35.29	6 of 17
66794	polyamine pathway	34.78	8 of 23
66794	(5R)-carbapenem carboxylate biosynthesis	33.33	1 of 3
66794	IAA biosynthesis	33.33	1 of 3
66794	nitrate assimilation	33.33	3 of 9
66794	3-phenylpropionate degradation	33.33	5 of 15
66794	acetyl CoA biosynthesis	33.33	1 of 3
66794	lipid A biosynthesis	33.33	3 of 9
66794	sphingosine metabolism	33.33	2 of 6
66794	allantoin degradation	33.33	3 of 9
66794	reductive acetyl coenzyme A pathway	28.57	2 of 7
66794	benzoyl-CoA degradation	28.57	2 of 7
66794	aclacinomycin biosynthesis	28.57	2 of 7
66794	degradation of hexoses	27.78	5 of 18
66794	vitamin B6 metabolism	27.27	3 of 11
66794	d-xylose degradation	27.27	3 of 11
66794	peptidoglycan biosynthesis	26.67	4 of 15
66794	sulfopterin metabolism	25	1 of 4
66794	methanogenesis from CO2	25	3 of 12
66794	carnitine metabolism	25	2 of 8
66794	CMP-KDO biosynthesis	25	1 of 4
66794	cyclohexanol degradation	25	1 of 4
66794	catecholamine biosynthesis	25	1 of 4
66794	vitamin E metabolism	25	1 of 4
66794	toluene degradation	25	1 of 4
66794	phenylpropanoid biosynthesis	23.08	3 of 13
66794	ascorbate metabolism	22.73	5 of 22

API zym

@ref	Control	Alkaline phosphatase	Esterase (C 4)	2-naphtyl caprylateEsterase Lipase (C 8)	Lipase (C 14)	L-leucyl-2-naphthylamideLeucine arylamidase	L-valyl-2-naphthylamideValine arylamidase	L-cystyl-2-naphthylamideCystine arylamidase	Trypsin	alpha- Chymotrypsin	Acid phosphatase	Naphthol-AS-BI-phosphateNaphthol-AS-BI-phosphohydrolase	alpha- Galactosidase	beta- Galactosidase	beta- Glucuronidase	alpha- Glucosidase	beta- Glucosidase	N-acetyl-beta- glucosaminidase	alpha- Mannosidase	alpha- Fucosidase
120747	-	-	+	+	-	+	-	-	-	-	-	-	-	-	-	-	-	-	-	-

Isolation, sampling and environmental information

Isolation

@ref	Geographic location	Country	Country ISO 3 Code	Continent
1375	Magadi Lake	Kenya	KEN	Africa
67770		Kenya	KEN	Africa
120747		Kenya	KEN	Africa

Taxonmaps

69479

Global distribution of 16S sequence AB663458 (>99% sequence identity) for Natrialba from Microbeatlas

Aquatic Samples	6
Soil Samples	3
Animal Samples
Plant Samples
Total Samples	9

Interaction and safety

Risk assessment

@ref	Biosafety level	Biosafety level comment
1375	1	Risk group (German classification) According to TRBA 466
120747	1	Risk group (French classification) According to TRBA 466

Sequence information

Genome sequences

@ref	Description	Assembly level	INSDC accession	BV-BRC accession	IMG accession	NCBI tax ID	Score
66792	ASM2562v1 assembly for Natrialba magadii ATCC 43099	complete	GCA_000025625	547559.16	646564555	547559	98.56
67770	ASM33787v1 assembly for Natrialba magadii ATCC 43099 MS-3	contig	GCA_000337875	547559.17	2554235492	547559	65.5

Genome browser: GCA_000025625

16S sequences

@ref	Description	Accession	Length	Database	NCBI tax ID
1375	Natrialba magadii gene for 16S rRNA, complete sequence, strain: JCM 8861	AB663458	1472		13769

GC content

1375

GC-content (mol%)63

Genome-based predictions

Predictions

Predictions from Deep Learning for Genome Sequence Data. R package version 0.3.1 based on: Natrialba magadii ATCC 43099
IMG: 646564555

@ref	Trait	Model	Prediction	Confidence in %	In training data
125439	spore_formation	BacteriaNetⓘ	no	60.30	no
125439	motility	BacteriaNetⓘ	no	60.30	no
125439	gram_stain	BacteriaNetⓘ	positive	80.10	no
125439	oxygen_tolerance	BacteriaNetⓘ	aerobe	95.10	no

Predictions from bacterial phenotypic traits through improved machine learning using high-quality, curated datasets based on: Natrialba magadii ATCC 43099 ATCC 43099
NCBI: GCA_000025625.1

@ref	Trait	Model	Prediction	Confidence in %	In training data
125438	gram-positive	gram-positiveⓘ	no	75.44	no
125438	anaerobic	anaerobicⓘ	no	87.82	no
125438	aerobic	aerobicⓘ	yes	81.56	no
125438	spore-forming	spore-formingⓘ	no	83.14	no
125438	thermophilic	thermophileⓘ	no	75.55	no
125438	flagellated	motile2+ⓘ	no	91.50	no

Literature

Topic	Title	Authors	Journal	DOI	Year
Metabolism	A Large and Phylogenetically Diverse Class of Type 1 Opsins Lacking a Canonical Retinal Binding Site.	Becker EA, Yao AI, Seitzer PM, Kind T, Wang T, Eigenheer R, Shao KS, Yarov-Yarovoy V, Facciotti MT.	PLoS One	10.1371/journal.pone.0156543	2016
Enzymology	Crystal structures of a halophilic archaeal malate synthase from Haloferax volcanii and comparisons with isoforms A and G.	Bracken CD, Neighbor AM, Lamlenn KK, Thomas GC, Schubert HL, Whitby FG, Howard BR.	BMC Struct Biol	10.1186/1472-6807-11-23	2011
	Draft genome sequence and annotation of Priestia aryabhattai MS3, a salt-tolerant plant growth-promoting rhizobacteria.	Pal DC, Khan SN, Karim MM.	Microbiol Resour Announc	10.1128/mra.00026-25	2025
	Transcriptomic Analysis Reveals Dysregulation of the Mycobiome and Archaeome and Distinct Oncogenic Characteristics according to Subtype and Gender in Papillary Thyroid Carcinoma.	John D, Yalamarty R, Barakchi A, Chen T, Chakladar J, Li WT, Ongkeko WM.	Int J Mol Sci	10.3390/ijms24043148	2023
Enzymology	Structural Characterization of the Xi Class Glutathione Transferase From the Haloalkaliphilic Archaeon Natrialba magadii.	Di Matteo A, Federici L, Masulli M, Carletti E, Santorelli D, Cassidy J, Paradisi F, Di Ilio C, Allocati N.	Front Microbiol	10.3389/fmicb.2019.00009	2019
	Diversity and Potential Multifunctionality of Archaeal CetZ Tubulin-like Cytoskeletal Proteins.	Brown HJ, Duggin IG.	Biomolecules	10.3390/biom13010134	2023
	Induction of Fungal Secondary Metabolites by Co-Culture with Actinomycete Producing HDAC Inhibitor Trichostatins.	Hwang GJ, Roh J, Son S, Lee B, Jang JP, Hur JS, Hong YS, Ahn JS, Ko SK, Jang JH.	J Microbiol Biotechnol	10.4014/jmb.2301.01017	2023
Phylogeny	Diversity of the Tryptophanase Gene and Its Evolutionary Implications in Living Organisms.	Boya BR, Kumar P, Lee JH, Lee J.	Microorganisms	10.3390/microorganisms9102156	2021
Genetics	Evaluation of the Persistence of Higher-Order Strand Symmetry in Genomic Sequences by Novel Word Symmetry Distance Analysis.	Huang B, Huang LF, Zhang SH.	Front Genet	10.3389/fgene.2019.00148	2019
Metabolism	Autocatalytic maturation of the Tat-dependent halophilic subtilase Nep produced by the archaeon Natrialba magadii.	Ruiz DM, Paggi RA, Gimenez MI, De Castro RE.	J Bacteriol	10.1128/jb.06792-11	2012
Genetics	Archaea Microbiome Dysregulated Genes and Pathways as Molecular Targets for Lung Adenocarcinoma and Squamous Cell Carcinoma.	Uzelac M, Li Y, Chakladar J, Li WT, Ongkeko WM.	Int J Mol Sci	10.3390/ijms231911566	2022
Stress	HtrAs are essential for the survival of the haloarchaeon Natrinema gari J7-2 in response to heat, high salinity, and toxic substances.	Luo H, Qu X, Deng X, He L, Wu Y, Liu Y, He D, Yin J, Wang B, Gan F, Tang B, Tang X-F.	Appl Environ Microbiol	10.1128/aem.02048-23	2024
	Redox and Thiols in Archaea.	Rawat M, Maupin-Furlow JA.	Antioxidants (Basel)	10.3390/antiox9050381	2020
Metabolism	2,3-Dihydroxybenzoate meta-Cleavage Pathway is Involved in o-Phthalate Utilization in Pseudomonas sp. strain PTH10.	Kasai D, Iwasaki T, Nagai K, Araki N, Nishi T, Fukuda M.	Sci Rep	10.1038/s41598-018-38077-2	2019
Metabolism	The core and unique proteins of haloarchaea.	Capes MD, DasSarma P, DasSarma S.	BMC Genomics	10.1186/1471-2164-13-39	2012
Transcriptome	Sequencing of seven haloarchaeal genomes reveals patterns of genomic flux.	Lynch EA, Langille MG, Darling A, Wilbanks EG, Haltiner C, Shao KS, Starr MO, Teiling C, Harkins TT, Edwards RA, Eisen JA, Facciotti MT.	PLoS One	10.1371/journal.pone.0041389	2012
Genetics	Gene-Family Extension Measures and Correlations.	Carmi G, Bolshoy A.	Life (Basel)	10.3390/life6030030	2016
Metabolism	Coexistence of bacterial leucyl-tRNA synthetases with archaeal tRNA binding domains that distinguish tRNA(Leu) in the archaeal mode.	Fang ZP, Wang M, Ruan ZR, Tan M, Liu RJ, Zhou M, Zhou XL, Wang ED.	Nucleic Acids Res	10.1093/nar/gku108	2014
Metabolism	The elusive third subunit IIa of the bacterial B-type oxidases: the enzyme from the hyperthermophile Aquifex aeolicus.	Prunetti L, Brugna M, Lebrun R, Giudici-Orticoni MT, Guiral M.	PLoS One	10.1371/journal.pone.0021616	2011
Genetics	Bipyrimidine Signatures as a Photoprotective Genome Strategy in G + C-rich Halophilic Archaea.	Jones DL, Baxter BK.	Life (Basel)	10.3390/life6030037	2016
Genetics	Phylogenomics of prokaryotic ribosomal proteins.	Yutin N, Puigbo P, Koonin EV, Wolf YI.	PLoS One	10.1371/journal.pone.0036972	2012
	Phylogeny and Taxonomy of Archaea: A Comparison of the Whole-Genome-Based CVTree Approach with 16S rRNA Sequence Analysis.	Zuo G, Xu Z, Hao B.	Life (Basel)	10.3390/life5010949	2015
	Halophiles and Their Biomolecules: Recent Advances and Future Applications in Biomedicine.	Corral P, Amoozegar MA, Ventosa A.	Mar Drugs	10.3390/md18010033	2019
Metabolism	The Archaeal Proteome Project advances knowledge about archaeal cell biology through comprehensive proteomics.	Schulze S, Adams Z, Cerletti M, De Castro R, Ferreira-Cerca S, Fufezan C, Gimenez MI, Hippler M, Jevtic Z, Knuppel R, Legerme G, Lenz C, Marchfelder A, Maupin-Furlow J, Paggi RA, Pfeiffer F, Poetsch A, Urlaub H, Pohlschroder M.	Nat Commun	10.1038/s41467-020-16784-7	2020
Enzymology	Phylogenetic Diversity of Lhr Proteins and Biochemical Activities of the Thermococcales aLhr2 DNA/RNA Helicase.	Hajj M, Langendijk-Genevaux P, Batista M, Quentin Y, Laurent S, Capeyrou R, Abdel-Razzak Z, Flament D, Chamieh H, Fichant G, Clouet-d'Orval B, Bouvier M.	Biomolecules	10.3390/biom11070950	2021
Metabolism	Dihydroxyacetone metabolism in Haloferax volcanii.	Ouellette M, Makkay AM, Papke RT.	Front Microbiol	10.3389/fmicb.2013.00376	2013
Metabolism	Ribonucleotide reduction - horizontal transfer of a required function spans all three domains.	Lundin D, Gribaldo S, Torrents E, Sjoberg BM, Poole AM.	BMC Evol Biol	10.1186/1471-2148-10-383	2010
Metabolism	Amino acid substitutions in cold-adapted proteins from Halorubrum lacusprofundi, an extremely halophilic microbe from antarctica.	DasSarma S, Capes MD, Karan R, DasSarma P.	PLoS One	10.1371/journal.pone.0058587	2013
Metabolism	The biosynthetic genes for prenylated phenazines are located at two different chromosomal loci of Streptomyces cinnamonensis DSM 1042.	Seeger K, Flinspach K, Haug-Schifferdecker E, Kulik A, Gust B, Fiedler HP, Heide L.	Microb Biotechnol	10.1111/j.1751-7915.2010.00234.x	2011
	Characterizing the DNA Methyltransferases of Haloferax volcanii via Bioinformatics, Gene Deletion, and SMRT Sequencing.	Ouellette M, Gogarten JP, Lajoie J, Makkay AM, Papke RT.	Genes (Basel)	10.3390/genes9030129	2018
	The complete genome sequence of Natrinema sp. J7-2, a haloarchaeon capable of growth on synthetic media without amino acid supplements.	Feng J, Liu B, Zhang Z, Ren Y, Li Y, Gan F, Huang Y, Chen X, Shen P, Wang L, Tang B, Tang XF.	PLoS One	10.1371/journal.pone.0041621	2012
Genetics	Related haloarchaeal pleomorphic viruses contain different genome types.	Sencilo A, Paulin L, Kellner S, Helm M, Roine E.	Nucleic Acids Res	10.1093/nar/gks215	2012
	Adaptation of the Haloarcula hispanica CRISPR-Cas system to a purified virus strictly requires a priming process.	Li M, Wang R, Zhao D, Xiang H.	Nucleic Acids Res	10.1093/nar/gkt1154	2014
Metabolism	Phylogenomic reconstruction of archaeal fatty acid metabolism.	Dibrova DV, Galperin MY, Mulkidjanian AY.	Environ Microbiol	10.1111/1462-2920.12359	2014
Biotechnology	Synthesis, production, and biotechnological applications of exopolysaccharides and polyhydroxyalkanoates by archaea.	Poli A, Di Donato P, Abbamondi GR, Nicolaus B.	Archaea	10.1155/2011/693253	2011
	Identification of polyhydroxyalkanoates in Halococcus and other haloarchaeal species.	Legat A, Gruber C, Zangger K, Wanner G, Stan-Lotter H.	Appl Microbiol Biotechnol	10.1007/s00253-010-2611-6	2010
Phylogeny	Quantifying homologous replacement of loci between haloarchaeal species.	Williams D, Gogarten JP, Papke RT.	Genome Biol Evol	10.1093/gbe/evs098	2012
Metabolism	Acthi, a thiazole biosynthesis enzyme, is essential for thiamine biosynthesis and CPC production in Acremonium chrysogenum.	Liu Y, Zhang W, Xie L, Liu H, Gong G, Zhu B, Hu Y.	Microb Cell Fact	10.1186/s12934-015-0235-3	2015
	Annotation of Protein Domains Reveals Remarkable Conservation in the Functional Make up of Proteomes Across Superkingdoms.	Nasir A, Naeem A, Khan MJ, Nicora HD, Caetano-Anolles G.	Genes (Basel)	10.3390/genes2040869	2011
Metabolism	Archaeosortases and exosortases are widely distributed systems linking membrane transit with posttranslational modification.	Haft DH, Payne SH, Selengut JD.	J Bacteriol	10.1128/jb.06026-11	2012
Enzymology	The UlaG protein family defines novel structural and functional motifs grafted on an ancient RNase fold.	Fernandez FJ, Garces F, Lopez-Estepa M, Aguilar J, Baldoma L, Coll M, Badia J, Vega MC.	BMC Evol Biol	10.1186/1471-2148-11-273	2011
	Colorectal Cancer Archaeome: A Metagenomic Exploration, Tunisia.	Mathlouthi NEH, Oumarou Hama H, Belguith I, Charfi S, Boudawara T, Lagier JC, Ammar Keskes L, Grine G, Gdoura R.	Curr Issues Mol Biol	10.3390/cimb45090477	2023
Metabolism	Proteomic Study of the Exponential-Stationary Growth Phase Transition in the Haloarchaea Natrialba magadii and Haloferax volcanii.	Cerletti M, Gimenez MI, Troetschel C, D' Alessandro C, Poetsch A, De Castro RE, Paggi RA, Paggi RA.	Proteomics	10.1002/pmic.201800116	2018
Enzymology	Functional roles of C-terminal extension (CTE) of salt-dependent peptidase activity of the Natrialba magadii extracellular protease (NEP).	Marem A, Okamoto DN, Oliveira LCG, Ruiz DM, Paggi RA, Kondo MY, Gouvea IE, Juliano MA, de Castro RE, Juliano L, Icimoto MY.	Int J Biol Macromol	10.1016/j.ijbiomac.2018.03.026	2018
	Production and characterization of an organic solvent activated protease from haloalkaliphilic bacterium Halobiforma sp. strain BNMIITR.	Gupta M, Choudhury B, Navani NK.	Heliyon	10.1016/j.heliyon.2024.e25084	2024
Metabolism	Navigating the structure-function-evolutionary relationship of CsaA chaperone in archaea.	Sharma A, Rani S, Goel M.	Crit Rev Microbiol	10.1080/1040841x.2017.1357535	2018
Genetics	Genomic manipulations in alkaliphilic haloarchaea demonstrated by a gene disruption in Natrialba magadii.	Derntl C, Selb R, Klein R, Alte B, Witte A.	FEMS Microbiol Lett	10.1093/femsle/fnv179	2015
	Expression, purification, and enzymatic characterization of an extracellular protease from Halococcus salifodinae.	Hong T, Pan R, Ke J, Luo Y, Hao Y, Chen L, Tu D, Dai Y, Chen T, Chen S.	Braz J Microbiol	10.1007/s42770-023-01114-y	2023
Genetics	Microbial diversity analysis of Chumathang geothermal spring, Ladakh, India.	Anu K, Kumari S, Choudhary G, Devi S.	Braz J Microbiol	10.1007/s42770-024-01284-3	2024
Genetics	Metagenomics insight into Puga geothermal geyser located in Himalayan Geothermal Belt (Trans-Himalayan Plateau) Ladakh, India.	Kumari S, Choudhary G, Anu K, Devi S.	Braz J Microbiol	10.1007/s42770-024-01408-9	2024
	Genetic identification of acetyl-CoA synthetases involved in acetate activation in Haloferax mediterranei.	Mitra R, Xu Y, Lin L, Guo J, Xu T, Zhou M, Guo F, Li H, Xiang H, Han J.	Appl Environ Microbiol	10.1128/aem.01843-24	2025
	Quorum sensing mediates morphology and motility transitions in the model archaeon Haloferax volcanii.	Chatterjee P, Consoli CE, Schiller H, Winter KK, McCallum ME, Schulze S, Pohlschroder M.	mBio	10.1128/mbio.00906-25	2025
	Nmag_2608, an extracellular ubiquitin-like domain-containing protein from the haloalkaliphilic archaeon Natrialba magadii.	Ordonez MV, Nercessian D, Conde RD.	Extremophiles	10.1007/s00792-012-0443-2	2012
	A TrmBL2-like transcription factor mediates the growth phase-dependent expression of halolysin SptA in a concentration-dependent manner in Natrinema gari J7-2.	Yin J, Liu Y, He D, Li P, Qiao M, Luo H, Qu X, Mei S, Wu Y, Sun Y, Gan F, Tang B, Tang X-F.	Appl Environ Microbiol	10.1128/aem.00741-24	2024
	Quorum Sensing in Halorubrum saccharovorum Facilitates Cross-Domain Signaling between Archaea and Bacteria.	Thompson TP, Busetti A, Gilmore BF.	Microorganisms	10.3390/microorganisms11051271	2023
Enzymology	Resurrection of Ancestral Malate Dehydrogenases Reveals the Evolutionary History of Halobacterial Proteins: Deciphering Gene Trajectories and Changes in Biochemical Properties.	Blanquart S, Groussin M, Le Roy A, Szollosi GJ, Girard E, Franzetti B, Gouy M, Madern D.	Mol Biol Evol	10.1093/molbev/msab146	2021
Pathogenicity	Archaeal virus entry and egress.	Kuiper BP, Schontag AMC, Oksanen HM, Daum B, Quax TEF.	Microlife	10.1093/femsml/uqad048	2024
	Comparative survival analysis of Deinococcus radiodurans and the haloarchaea Natrialba magadii and Haloferax volcanii exposed to vacuum ultraviolet irradiation.	Abrevaya XC, Paulino-Lima IG, Galante D, Rodrigues F, Mauas PJ, Corton E, Lage Cde A.	Astrobiology	10.1089/ast.2011.0607	2011
Enzymology	The LonB protease controls membrane lipids composition and is essential for viability in the extremophilic haloarchaeon Haloferax volcanii.	Cerletti M, Martinez MJ, Gimenez MI, Sastre DE, Paggi RA, De Castro RE.	Environ Microbiol	10.1111/1462-2920.12385	2014
	Secondary structure determination by FTIR of an archaeal ubiquitin-like polypeptide from Natrialba magadii.	Ordonez MV, Guillen J, Nercessian D, Villalain J, Conde RD.	Eur Biophys J	10.1007/s00249-011-0719-y	2011
Enzymology	Peptide synthesis catalysed by a haloalkaliphilic serine protease from the archaeon Natrialba magadii (Nep).	Ruiz DM, Iannuci NB, Cascone O, De Castro RE.	Lett Appl Microbiol	10.1111/j.1472-765x.2010.02955.x	2010
Genetics	Comprehensive whole metagenomics analysis uncovers microbial community and resistome variability across anthropogenically contaminated soils in urban and suburban areas of Tamil Nadu, India.	Vasanthrao R, Nidhin IK, Taj Z, Chattopadhyay I.	Front Microbiol	10.3389/fmicb.2025.1649872	2025
Metabolism	The Lon protease from the haloalkaliphilic archaeon Natrialba magadii is transcriptionally linked to a cluster of putative membrane proteases and displays DNA-binding activity.	Sastre DE, Paggi RA, De Castro RE.	Microbiol Res	10.1016/j.micres.2010.07.002	2011
Enzymology	Growth phase-dependent biosynthesis of Nep, a halolysin-like protease secreted by the alkaliphilic haloarchaeon Natrialba magadii.	Paggi RA, Madrid EA, D'Alessandro CP, Cerletti M, De Castro RE.	Lett Appl Microbiol	10.1111/j.1472-765x.2010.02855.x	2010
	Archaea-based microbial fuel cell operating at high ionic strength conditions.	Abrevaya XC, Sacco N, Mauas PJ, Corton E.	Extremophiles	10.1007/s00792-011-0394-z	2011
Enzymology	Correlation between catalysis and tertiary structure arrangement in an archaeal halophilic subtilase.	Souza TA, Okamoto DN, Ruiz DM, Oliveira LC, Kondo MY, Tersario IL, Juliano L, De Castro RE, Gouvea IE, Murakami MT.	Biochimie	10.1016/j.biochi.2011.11.011	2012
Pathogenicity	Effect of nutritional conditions on extracellular protease production by the haloalkaliphilic archaeon Natrialba magadii.	D'Alessandro CP, De Castro RE, Gimenez MI, Paggi RA.	Lett Appl Microbiol	10.1111/j.1472-765x.2007.02122.x	2007
Enzymology	An alkaline serine-proteinase from a bacterium isolated from bat feces: purification and characterization.	Tanskul S, Hiraga K, Takada K, Rungratchote S, Suntinanalert P, Oda K.	Biosci Biotechnol Biochem	10.1271/bbb.90289	2009
Enzymology	Effect of organic solvents on the activity and stability of an extracellular protease secreted by the haloalkaliphilic archaeon Natrialba magadii.	Ruiz DM, De Castro RE.	J Ind Microbiol Biotechnol	10.1007/s10295-006-0174-4	2007
	Presence of structural homologs of ubiquitin in haloalkaliphilic Archaea.	Nercessian D, Marino Buslje C, Ordonez MV, De Castro RE, Conde RD.	Int Microbiol		2009
Phylogeny	Diversity, evolution, and classification of the RNA-guided nucleases TnpB and Cas12.	Altae-Tran H, Shmakov SA, Makarova KS, Wolf YI, Kannan S, Zhang F, Koonin EV.	Proc Natl Acad Sci U S A	10.1073/pnas.2308224120	2023
Pathogenicity	Dual-RNAseq Analysis Unravels Virus-Host Interactions of MetSV and Methanosarcina mazei.	Gehlert FO, Sauerwein T, Weidenbach K, Repnik U, Hallack D, Forstner KU, Schmitz RA.	Viruses	10.3390/v14112585	2022
	The lysogenic region of virus phiCh1: identification of a repressor-operator system and determination of its activity in halophilic Archaea.	Iro M, Klein R, Galos B, Baranyi U, Rossler N, Witte A.	Extremophiles	10.1007/s00792-006-0040-3	2007
Phylogeny	Phylogenetic relationships within the family Halobacteriaceae inferred from rpoB' gene and protein sequences.	Enache M, Itoh T, Fukushima T, Usami R, Dumitru L, Kamekura M.	Int J Syst Evol Microbiol	10.1099/ijs.0.65190-0	2007
Metabolism	Two immunologically distinct types of protofilaments can be identified in Natrialba magadii flagella.	Pyatibratov MG, Leonard K, Tarasov VY, Fedorov OV.	FEMS Microbiol Lett	10.1111/j.1574-6968.2002.tb11239.x	2002
Genetics	Natrialba magadii virus phiCh1: first complete nucleotide sequence and functional organization of a virus infecting a haloalkaliphilic archaeon.	Klein R, Baranyi U, Rossler N, Greineder B, Scholz H, Witte A.	Mol Microbiol	10.1046/j.1365-2958.2002.03064.x	2002
Enzymology	Stability of Natrialba magadii NDP kinase: comparisons with other halophilic proteins.	Polosina YY, Zamyatkin DF, Kostyukova AS, Filimonov VV, Fedorov OV.	Extremophiles	10.1007/s007920100232	2002
Phylogeny	Spatiotemporal structure and composition of the microbial communities in hypersaline Lake Magadi, Kenya.	Kipnyargis A, Kenya E, Khamis F, Mwirichia R.	F1000Res	10.12688/f1000research.134465.2	2024
	Halophilic Bacteria of Lunsu Produce an Array of Industrially Important Enzymes with Salt Tolerant Activity.	Gupta S, Sharma P, Dev K, Sourirajan A.	Biochem Res Int	10.1155/2016/9237418	2016
Genetics	A manual curation strategy to improve genome annotation: application to a set of haloarchael genomes.	Pfeiffer F, Oesterhelt D.	Life (Basel)	10.3390/life5021427	2015
Metabolism	Mechanisms for Induction of Microbial Extracellular Proteases in Response to Exterior Proteins.	Zhang YZ, Zhang WX, Chen XL.	Appl Environ Microbiol	10.1128/aem.01036-20	2020
Metabolism	The structural protein E of the archaeal virus phiCh1: evidence for processing in Natrialba magadii during virus maturation.	Klein R, Greineder B, Baranyi U, Witte A.	Virology	10.1006/viro.2000.0565	2000
	Inversion within the haloalkaliphilic virus phi Ch1 DNA results in differential expression of structural proteins.	Rossler N, Klein R, Scholz H, Witte A.	Mol Microbiol	10.1111/j.1365-2958.2003.03983.x	2004
Metabolism	Detection of an intracellular protease inhibitor in archaea.	Gimenez MI, Sanchez JJ, De Castro RE.	Curr Microbiol	10.1007/s00284-002-3861-z	2003
Enzymology	Extracellular protease of Natrialba magadii: purification and biochemical characterization.	Gimenez MI, Studdert CA, Sanchez JJ, De Castro RE.	Extremophiles	10.1007/s007920070033	2000
	Exploring the Molecular Machinery of Denitrification in Haloferax mediterranei Through Proteomics.	Torregrosa-Crespo J, Pire C, Richardson DJ, Martinez-Espinosa RM.	Front Microbiol	10.3389/fmicb.2020.605859	2020
Metabolism	Phylogenomic Analysis of beta-Lactamase in Archaea and Bacteria Enables the Identification of Putative New Members.	Keshri V, Panda A, Levasseur A, Rolain JM, Pontarotti P, Raoult D.	Genome Biol Evol	10.1093/gbe/evy028	2018
	Halolysin R4 of Haloferax mediterranei confers its host antagonistic and defensive activities.	Chen S, Sun S, Wang R, Feng H, Xiang H.	Appl Environ Microbiol	10.1128/aem.02889-20	2021
Metabolism	Duplication of leucyl-tRNA synthetase in an archaeal extremophile may play a role in adaptation to variable environmental conditions.	Weitzel CS, Li L, Zhang C, Eilts KK, Bretz NM, Gatten AL, Whitaker RJ, Martinis SA.	J Biol Chem	10.1074/jbc.ra118.006481	2020
	Microbial electroactive biofilms dominated by Geoalkalibacter spp. from a highly saline-alkaline environment.	Yadav S, Patil SA.	NPJ Biofilms Microbiomes	10.1038/s41522-020-00147-7	2020
	Geochemical constraints on the Hadean environment from mineral fingerprints of prokaryotes.	Novoselov AA, Silva D, Schneider J, Abrevaya XC, Chaffin MS, Serrano P, Navarro MS, Conti MJ, Souza Filho CR.	Sci Rep	10.1038/s41598-017-04161-2	2017
Phylogeny	Diversity of alkaliphilic halobacteria: proposals for transfer of Natronobacterium vacuolatum, Natronobacterium magadii, and Natronobacterium pharaonis to Halorubrum, Natrialba, and Natronomonas gen. nov., respectively, as Halorubrum vacuolatum comb. nov., Natrialba magadii comb. nov., and Natronomonas pharaonis comb. nov., respectively.	Kamekura M, Dyall-Smith ML, Upasani V, Ventosa A, Kates M.	Int J Syst Bacteriol	10.1099/00207713-47-3-853	1997
Metabolism	ThiN as a Versatile Domain of Transcriptional Repressors and Catalytic Enzymes of Thiamine Biosynthesis.	Hwang S, Cordova B, Abdo M, Pfeiffer F, Maupin-Furlow JA.	J Bacteriol	10.1128/jb.00810-16	2017
	A Halocin Promotes DNA Uptake in Haloferax mediterranei.	Chen S, Sun S, Korfanty GA, Liu J, Xiang H.	Front Microbiol	10.3389/fmicb.2019.01960	2019
	A comprehensive history of motility and Archaellation in Archaea.	Jarrell KF, Albers SV, Machado JNS.	FEMS Microbes	10.1093/femsmc/xtab002	2021
	Low complexity regions in the proteins of prokaryotes perform important functional roles and are highly conserved.	Ntountoumi C, Vlastaridis P, Mossialos D, Stathopoulos C, Iliopoulos I, Promponas V, Oliver SG, Amoutzias GD.	Nucleic Acids Res	10.1093/nar/gkz730	2019
Enzymology	The archaeal halophilic virus-encoded Dam-like methyltransferase M. phiCh1-I methylates adenine residues and complements dam mutants in the low salt environment of Escherichia coli.	Baranyi U, Klein R, Lubitz W, Kruger DH, Witte A.	Mol Microbiol	10.1046/j.1365-2958.2000.01786.x	2000
Metabolism	Trehalose/2-sulfotrehalose biosynthesis and glycine-betaine uptake are widely spread mechanisms for osmoadaptation in the Halobacteriales.	Youssef NH, Savage-Ashlock KN, McCully AL, Luedtke B, Shaw EI, Hoff WD, Elshahed MS.	ISME J	10.1038/ismej.2013.165	2014
Metabolism	C-terminal Domain of Leucyl-tRNA Synthetase from Pathogenic Candida albicans Recognizes both tRNASer and tRNALeu.	Ji QQ, Fang ZP, Ye Q, Ruan ZR, Zhou XL, Wang ED.	J Biol Chem	10.1074/jbc.m115.699777	2016
Genetics	The Exploration of Novel Regulatory Relationships Drives Haloarchaeal Operon-Like Structural Dynamics over Short Evolutionary Distances.	Seitzer P, Yao AI, Cisneros A, Facciotti MT.	Microorganisms	10.3390/microorganisms8121900	2020
Genetics	Characterization of the Microbial Population Inhabiting a Solar Saltern Pond of the Odiel Marshlands (SW Spain).	Gomez-Villegas P, Vigara J, Leon R.	Mar Drugs	10.3390/md16090332	2018
	Sec-Dependent Secretion of Subtilase SptE in Haloarchaea Facilitates Its Proper Folding and Heterocatalytic Processing by Halolysin SptA Extracellularly.	Mei S, Li M, Sun Y, Deng X, Chen N, Liu Y, Yin J, Luo H, Wu Y, He D, Gan F, Tang B, Tang XF.	Appl Environ Microbiol	10.1128/aem.00246-22	2022
	Influence of Origin Recognition Complex Proteins on the Copy Numbers of Three Chromosomes in Haloferax volcanii.	Ludt K, Soppa J.	J Bacteriol	10.1128/jb.00161-18	2018
Metabolism	Tracing the Repertoire of Promiscuous Enzymes along the Metabolic Pathways in Archaeal Organisms.	Martinez-Nunez MA, Rodriguez-Escamilla Z, Rodriguez-Vazquez K, Perez-Rueda E.	Life (Basel)	10.3390/life7030030	2017
	Gene cloning and heterologous synthesis of a haloalkaliphilic extracellular protease of Natrialba magadii (Nep).	De Castro RE, Ruiz DM, Gimenez MI, Silveyra MX, Paggi RA, Maupin-Furlow JA.	Extremophiles	10.1007/s00792-008-0174-6	2008
	The PL6-Family Plasmids of Haloquadratum Are Virus-Related.	Dyall-Smith M, Pfeiffer F.	Front Microbiol	10.3389/fmicb.2018.01070	2018
	Sequencing of flagellin genes from Natrialba magadii provides new insight into evolutionary aspects of archaeal flagellins.	Serganova I, Ksenzenko V, Serganov A, Meshcheryakova I, Pyatibratov M, Vakhrusheva O, Metlina A, Fedorov O.	J Bacteriol	10.1128/jb.184.1.318-322.2002	2002
	Interaction of bacteria and archaea in a microbial fuel cell with ITO anode.	Jiang Q, Xing D, Zhang L, Sun R, Zhang J, Zhong Y, Feng Y, Feng Y, Ren N.	RSC Adv	10.1039/c8ra01207e	2018
Pathogenicity	Exploring short k-mer profiles in cells and mobile elements from Archaea highlights the major influence of both the ecological niche and evolutionary history.	Bize A, Midoux C, Mariadassou M, Schbath S, Forterre P, Da Cunha V.	BMC Genomics	10.1186/s12864-021-07471-y	2021
	Bacteria have numerous distinctive groups of phage-plasmids with conserved phage and variable plasmid gene repertoires.	Pfeifer E, Moura de Sousa JA, Touchon M, Rocha EPC.	Nucleic Acids Res	10.1093/nar/gkab064	2021
Metabolism	First insights into the entry process of hyperthermophilic archaeal viruses.	Quemin ER, Lucas S, Daum B, Quax TE, Kuhlbrandt W, Forterre P, Albers SV, Prangishvili D, Krupovic M.	J Virol	10.1128/jvi.02742-13	2013
Phylogeny	Halobacterium salinarum virus ChaoS9, a Novel Halovirus Related to PhiH1 and PhiCh1.	Dyall-Smith M, Palm P, Wanner G, Witte A, Oesterhelt D, Pfeiffer F.	Genes (Basel)	10.3390/genes10030194	2019
	Halolysin SptA, a Serine Protease, Contributes to Growth-Phase Transition of Haloarchaeon Natrinema sp. J7-2, and Its Expression Involves Cooperative Action of Multiple Cis-Regulatory Elements.	Li M, Yin J, Mei S, Wang X, Tang XF, Tang B.	Front Microbiol	10.3389/fmicb.2018.01799	2018
	Diversity of cultivated aerobic poly-hydrolytic bacteria in saline alkaline soils.	Sorokin DY, Kolganova TV, Khijniak TV, Jones BE, Kublanov IV.	PeerJ	10.7717/peerj.3796	2017
	Succinyl-CoA:Mesaconate CoA-Transferase and Mesaconyl-CoA Hydratase, Enzymes of the Methylaspartate Cycle in Haloarcula hispanica.	Borjian F, Johnsen U, Schonheit P, Berg IA.	Front Microbiol	10.3389/fmicb.2017.01683	2017
Genetics	Open Issues for Protein Function Assignment in Haloferax volcanii and Other Halophilic Archaea.	Pfeiffer F, Dyall-Smith M.	Genes (Basel)	10.3390/genes12070963	2021
	Isolation, characterization and exploring biotechnological potential of halophilic archaea from salterns of western India.	Singh A, Singh AK.	3 Biotech	10.1007/s13205-017-1072-3	2018
Metabolism	The methylaspartate cycle in haloarchaea and its possible role in carbon metabolism.	Borjian F, Han J, Hou J, Xiang H, Berg IA.	ISME J	10.1038/ismej.2015.132	2016
Enzymology	Wide distribution among halophilic archaea of a novel polyhydroxyalkanoate synthase subtype with homology to bacterial type III synthases.	Han J, Hou J, Liu H, Cai S, Feng B, Zhou J, Xiang H.	Appl Environ Microbiol	10.1128/aem.01117-10	2010
Pathogenicity	Self-protective responses to norvaline-induced stress in a leucyl-tRNA synthetase editing-deficient yeast strain.	Ji QQ, Fang ZP, Ye Q, Chi CW, Wang ED.	Nucleic Acids Res	10.1093/nar/gkx487	2017
	Genome-wide DNA methylation analysis of Haloferax volcanii H26 and identification of DNA methyltransferase related PD-(D/E)XK nuclease family protein HVO_A0006.	Ouellette M, Jackson L, Chimileski S, Papke RT.	Front Microbiol	10.3389/fmicb.2015.00251	2015
Metabolism	Ser(262) determines the chloride-dependent colour tuning of a new halorhodopsin from Haloquadratum walsbyi.	Fu HY, Chang YN, Jheng MJ, Yang CS.	Biosci Rep	10.1042/bsr20120054	2012
Phylogeny	Computational Exploration of Putative LuxR Solos in Archaea and Their Functional Implications in Quorum Sensing.	Rajput A, Kumar M.	Front Microbiol	10.3389/fmicb.2017.00798	2017
Metabolism	Protein synthesis controls phosphate homeostasis.	Pontes MH, Groisman EA.	Genes Dev	10.1101/gad.309245.117	2018
Enzymology	Purification and characterization of an extreme halothermophilic protease from a halophilic bacterium Chromohalobacter sp. TVSP101.	Vidyasagar M, Prakash S, Mahajan V, Shouche YS, Sreeramulu K.	Braz J Microbiol	10.1590/s1517-83822009000100002	2009
Metabolism	The Anabaena sensory rhodopsin transducer defines a novel superfamily of prokaryotic small-molecule binding domains.	De Souza RF, Iyer LM, Aravind L.	Biol Direct	10.1186/1745-6150-4-25	2009
	Antarctic archaea-virus interactions: metaproteome-led analysis of invasion, evasion and adaptation.	Tschitschko B, Williams TJ, Allen MA, Paez-Espino D, Kyrpides N, Zhong L, Raftery MJ, Cavicchioli R.	ISME J	10.1038/ismej.2015.110	2015
Phylogeny	Dynamic viral populations in hypersaline systems as revealed by metagenomic assembly.	Emerson JB, Thomas BC, Andrade K, Allen EE, Heidelberg KB, Banfield JF.	Appl Environ Microbiol	10.1128/aem.01212-12	2012
Metabolism	Cloning, overexpression, purification, and characterization of a polyextremophilic beta-galactosidase from the Antarctic haloarchaeon Halorubrum lacusprofundi.	Karan R, Capes MD, DasSarma P, DasSarma S.	BMC Biotechnol	10.1186/1472-6750-13-3	2013
Enzymology	A novel clade of unique eukaryotic ribonucleotide reductase R2 subunits is exclusive to apicomplexan parasites.	Munro JB, Jacob CG, Silva JC.	J Mol Evol	10.1007/s00239-013-9583-y	2013
Enzymology	Purification and characterization of a thermostable, haloalkaliphilic extracellular serine protease from the extreme halophilic archaeon Halogeometricum borinquense strain TSS101.	Vidyasagar M, Prakash S, Litchfield C, Sreeramulu K.	Archaea	10.1155/2006/430763	2006
Phylogeny	Ancient origin of the divergent forms of leucyl-tRNA synthetases in the Halobacteriales.	Andam CP, Harlow TJ, Papke RT, Gogarten JP.	BMC Evol Biol	10.1186/1471-2148-12-85	2012
	Molecular mechanism of distinct salt-dependent enzyme activity of two halophilic nucleoside diphosphate kinases.	Yamamura A, Ichimura T, Kamekura M, Mizuki T, Usami R, Makino T, Ohtsuka J, Miyazono K, Okai M, Nagata K, Tanokura M.	Biophys J	10.1016/j.bpj.2009.03.012	2009
	Site- and horizon-specific patterns of microbial community structure and enzyme activities in permafrost-affected soils of Greenland.	Gittel A, Barta J, Kohoutova I, Schnecker J, Wild B, Capek P, Kaiser C, Torsvik VL, Richter A, Schleper C, Urich T.	Front Microbiol	10.3389/fmicb.2014.00541	2014
Metabolism	Chitin accelerates activation of a novel haloarchaeal serine protease that deproteinizes chitin-containing biomass.	Zhang Y, Wang M, Du X, Tang W, Zhang L, Li M, Wang J, Tang B, Tang XF.	Appl Environ Microbiol	10.1128/aem.01196-14	2014
Genetics	Assessing diversity of DNA structure-related sequence features in prokaryotic genomes.	Huang Y, Mrazek J.	DNA Res	10.1093/dnares/dst057	2014
Metabolism	Translational fidelity maintenance preventing Ser mis-incorporation at Thr codon in protein from eukaryote.	Zhou XL, Ruan ZR, Huang Q, Tan M, Wang ED.	Nucleic Acids Res	10.1093/nar/gks982	2013
Metabolism	Glycerol-mediated repression of glucose metabolism and glycerol kinase as the sole route of glycerol catabolism in the haloarchaeon Haloferax volcanii.	Sherwood KE, Cano DJ, Maupin-Furlow JA.	J Bacteriol	10.1128/jb.00131-09	2009
	System analysis of synonymous codon usage biases in archaeal virus genomes.	Li S, Yang J.	J Theor Biol	10.1016/j.jtbi.2014.03.022	2014
	Haloarchaea and the formation of gas vesicles.	Pfeifer F.	Life (Basel)	10.3390/life5010385	2015
Metabolism	A rhomboid protease gene deletion affects a novel oligosaccharide N-linked to the S-layer glycoprotein of Haloferax volcanii.	Parente J, Casabuono A, Ferrari MC, Paggi RA, De Castro RE, Couto AS, Gimenez MI.	J Biol Chem	10.1074/jbc.m113.546531	2014
Enzymology	Functional insight into the C-terminal extension of halolysin SptA from haloarchaeon Natrinema sp. J7.	Xu Z, Du X, Li T, Gan F, Tang B, Tang XF.	PLoS One	10.1371/journal.pone.0023562	2011
Metabolism	Archaeal JAB1/MPN/MOV34 metalloenzyme (HvJAMM1) cleaves ubiquitin-like small archaeal modifier proteins (SAMPs) from protein-conjugates.	Hepowit NL, Uthandi S, Miranda HV, Toniutti M, Prunetti L, Olivarez O, De Vera IM, Fanucci GE, Chen S, Maupin-Furlow JA.	Mol Microbiol	10.1111/mmi.12038	2012
Metabolism	Metabolic capabilities and systems fluctuations in Haloarcula marismortui revealed by integrative genomics and proteomics analyses.	Chu LJ, Yang H, Shih P, Kao Y, Tsai YS, Chen J, Huang G, Weng RR, Ting YS, Fang X, von Haller PD, Goodlett DR, Ng WV.	J Proteome Res	10.1021/pr200290x	2011
Genetics	Reconstructing viral genomes from the environment using fosmid clones: the case of haloviruses.	Garcia-Heredia I, Martin-Cuadrado AB, Mojica FJ, Santos F, Mira A, Anton J, Rodriguez-Valera F.	PLoS One	10.1371/journal.pone.0033802	2012
Metabolism	LccA, an archaeal laccase secreted as a highly stable glycoprotein into the extracellular medium by Haloferax volcanii.	Uthandi S, Saad B, Humbard MA, Maupin-Furlow JA.	Appl Environ Microbiol	10.1128/aem.01757-09	2010
	Phages in nature.	Clokie MR, Millard AD, Letarov AV, Heaphy S.	Bacteriophage	10.4161/bact.1.1.14942	2011
Enzymology	Sequence analysis of an Archaeal virus isolated from a hypersaline lake in Inner Mongolia, China.	Pagaling E, Haigh RD, Grant WD, Cowan DA, Jones BE, Ma Y, Ventosa A, Heaphy S.	BMC Genomics	10.1186/1471-2164-8-410	2007
	Protein attributes contribute to halo-stability, bioinformatics approach.	Ebrahimie E, Ebrahimi M, Sarvestani NR, Ebrahimi M.	Saline Syst	10.1186/1746-1448-7-1	2011
Enzymology	Sulfolobus tengchongensis spindle-shaped virus STSV1: virus-host interactions and genomic features.	Xiang X, Chen L, Huang X, Luo Y, She Q, Huang L.	J Virol	10.1128/jvi.79.14.8677-8686.2005	2005
Genetics	Phylogenetically driven sequencing of extremely halophilic archaea reveals strategies for static and dynamic osmo-response.	Becker EA, Seitzer PM, Tritt A, Larsen D, Krusor M, Yao AI, Wu D, Madern D, Eisen JA, Darling AE, Facciotti MT.	PLoS Genet	10.1371/journal.pgen.1004784	2014
Genetics	Intragenomic heterogeneity and intergenomic recombination among haloarchaeal rRNA genes.	Boucher Y, Douady CJ, Sharma AK, Kamekura M, Doolittle WF.	J Bacteriol	10.1128/jb.186.12.3980-3990.2004	2004
	Low-pass sequencing for microbial comparative genomics.	Goo YA, Roach J, Glusman G, Baliga NS, Deutsch K, Pan M, Kennedy S, DasSarma S, Ng WV, Hood L.	BMC Genomics	10.1186/1471-2164-5-3	2004
Genetics	A comparative genomics perspective on the genetic content of the alkaliphilic haloarchaeon Natrialba magadii ATCC 43099T.	Siddaramappa S, Challacombe JF, Decastro RE, Pfeiffer F, Sastre DE, Gimenez MI, Paggi RA, Detter JC, Davenport KW, Goodwin LA, Kyrpides N, Tapia R, Pitluck S, Lucas S, Woyke T, Maupin-Furlow JA	BMC Genomics	10.1186/1471-2164-13-165	2012
Genetics	Non-contiguous finished genome sequence and description of Halopiger goleamassiliensis sp. nov.	Ikram HI, Catherine R, Caroline M, Didier R, Hocine H, Christelle D.	Stand Genomic Sci	10.4056/sigs.4618288	2014
Genetics	Non-contiguous finished genome sequence and description of Halopiger djelfamassiliensis sp. nov.	Hassani II, Robert C, Michelle C, Raoult D, Hacene H, Desnues C.	Stand Genomic Sci	10.4056/sigs.4578289	2013
Phylogeny	Natrialba swarupiae sp. nov., a halophilic archaeon isolated from a hypersaline lake in India.	Kajale S, Deshpande N, Pali S, Shouche Y, Sharma A	Int J Syst Evol Microbiol	10.1099/ijsem.0.003986	2020

References

#1375	Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 3394
#20215	Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 )
#38508	; Curators of the CIP;
#66792	Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) .
#66794	Antje Chang, Lisa Jeske, Sandra Ulbrich, Julia Hofmann, Julia Koblitz, Ida Schomburg, Meina Neumann-Schaal, Dieter Jahn, Dietmar Schomburg: BRENDA, the ELIXIR core data resource in 2021: new developments and updates. Nucleic Acids Res. 49: D498 - D508 2020 ( DOI 10.1093/nar/gkaa1025 , PubMed 33211880 )
#67770	Japan Collection of Microorganism (JCM) ; Curators of the JCM;
#68382	Automatically annotated from API zym .
#69479	João F Matias Rodrigues, Janko Tackmann,Gregor Rot, Thomas SB Schmidt, Lukas Malfertheiner, Mihai Danaila,Marija Dmitrijeva, Daniela Gaio, Nicolas Näpflin and Christian von Mering. University of Zurich.: MicrobeAtlas 1.0 beta .
#120747	Collection of Institut Pasteur ; Curators of the CIP; CIP 104546
#125438	Julia Koblitz, Lorenz Christian Reimer, Rüdiger Pukall, Jörg Overmann: Predicting bacterial phenotypic traits through improved machine learning using high-quality, curated datasets. 2024 ( DOI 10.1101/2024.08.12.607695 )
#125439	Philipp Münch, René Mreches, Martin Binder, Hüseyin Anil Gündüz, Xiao-Yin To, Alice McHardy: deepG: Deep Learning for Genome Sequence Data. R package version 0.3.1 .
#126262	A. Lissin, I. Schober, J. F. Witte, H. Lüken, A. Podstawka, J. Koblitz, B. Bunk, P. Dawyndt, P. Vandamme, P. de Vos, J. Overmann, L. C. Reimer: StrainInfo—the central database for linked microbial strain identifiers. ( DOI 10.1093/database/baaf059 )

Rate our new design

Content

About us

Natrialba magadii (DSM 3394, ATCC 43099, CCM 3739)

Name and taxonomic classification

Morphology

Cell morphology

Culture and growth conditions

Culture medium

Culture temp

Physiology and metabolism

Oxygen tolerance

Observation

Metabolite utilization

Metabolite production

Enzymes

Pathway annotation

API zym

Isolation, sampling and environmental information

Isolation

Taxonmaps

Interaction and safety

Risk assessment

Sequence information

Genome sequences

Genome browser: GCA_000025625

16S sequences

GC content

Genome-based predictions

Predictions

Literature

Literature

References

BacDive

Help

Social Media