Lysobacter enzymogenes (DSM 2043, ATCC 29487, VKM B-2235)

Name: Lysobacter enzymogenes (DSM 2043, ATCC 29487, VKM B-2235)
Creator: BacDive
License: http://creativecommons.org/licenses/by/4.0/

BacDive ID 17476

Type strain

Strain Designation Reichenbach Ly e 1, strain 495

Culture col. no. DSM 2043 ATCC 29487 VKM B-2235 CCUG 7833 LMG 8762 8 more

NCBI tax ID(s) 69

Special Collections DSMZ CCUG KCTC Literature strains

History <- H. Reichenbach, Ly e1 <- P. Christensen, UASM 495 <- F.D. Cook <- LMG <- NCIMB <- E Peterson

Links

Lysobacter enzymogenes Reichenbach Ly e 1 is an aerobe, Gram-negative bacterium that was isolated from soil.

Gram-negative aerobe genome sequence 16S sequence Bacteria

Name and taxonomic classification

SI-ID 13719

LMG 8762,ATCC 29487,CCRC 11654,DSM 2043,NCIB 9924,NCIMB 9924,VKM B-2235,BCRC 11654,KCTC 12131,CCUG 7833

@ref 20215

Last LPSN update 2026-02-09 11:22:14

Domain Bacteria

Phylum Pseudomonadota

Class Gammaproteobacteria

Order Lysobacterales

Family Lysobacteraceae

Genus Lysobacter

Species Lysobacter enzymogenes

Full scientific name Lysobacter enzymogenes Christensen and Cook 1978 (Approved Lists 1980)

BacDive ID	Other strains from **Lysobacter enzymogenes** (1)	Type strain
17478	L. enzymogenes U 410, DSM 10690

Morphology

Cell morphology

@ref	Gram stain	Confidence
67771	negative
125439	negative	92
125438	negative	97.25

Culture and growth conditions

Culture medium

@ref	Name	Growth	Medium link	Composition
685	CY-AGAR (DSMZ Medium 67)		Medium recipe at MediaDive	Name: CY-AGAR (DSMZ Medium 67) Composition: Agar 15.0 g/l Casitone 3.0 g/l CaCl2 x 2 H2O 1.36 g/l Yeast extract 1.0 g/l Distilled water
43356	MacConkey Agar

Culture temp

@ref	Growth	Type	Temperature (°C)
685	positive	growth	28
45040	positive	growth	30
67771	positive	growth	30

Physiology and metabolism

Oxygen tolerance

@ref	Oxygen tolerance	Confidence
45040	aerobe
67771	aerobe
125439	obligate aerobe	99.2

Compound production

@ref	Compound
685	nucleases, extracellular
685	protease
20216	Nucleases
20216	Proteases

Metabolite utilization

@ref	Chebi-ID	Metabolite	Utilization activity	Kind of utilization tested
68369	17128 ChEBI	adipate	-	assimilation	from API 20NE
43356	2509 ChEBI	agar	-	degradation
43356	58187 ChEBI	alginate	+	degradation
43356	28938 ChEBI	ammonium	+	nitrogen source
68369	29016 ChEBI	arginine	-	hydrolysis	from API 20NE
43356	22653 ChEBI	asparagine	+	nitrogen source
43356	85146 ChEBI	carboxymethylcellulose	+	degradation
43356	62968 ChEBI	cellulose	-	degradation
43356	17029 ChEBI	chitin	+	degradation
43356	16947 ChEBI	citrate	+	assimilation
68369	17634 ChEBI	D-glucose	+	assimilation	from API 20NE
68369	17634 ChEBI	D-glucose	-	fermentation	from API 20NE
68369	16899 ChEBI	D-mannitol	-	assimilation	from API 20NE
68369	27689 ChEBI	decanoate	-	assimilation	from API 20NE
68369	4853 ChEBI	esculin	+	hydrolysis	from API 20NE
43356	5291 ChEBI	gelatin	+	degradation
68369	5291 ChEBI	gelatin	+	hydrolysis	from API 20NE
68369	24265 ChEBI	gluconate	-	assimilation	from API 20NE
43356	17234 ChEBI	glucose	-	fermentation
68369	30849 ChEBI	L-arabinose	-	assimilation	from API 20NE
43356	6364 ChEBI	laminarin	+	degradation
68369	25115 ChEBI	malate	+	assimilation	from API 20NE
68369	17306 ChEBI	maltose	+	assimilation	from API 20NE
68369	59640 ChEBI	N-acetylglucosamine	+	assimilation	from API 20NE
68369	17632 ChEBI	nitrate	-	reduction	from API 20NE
43356	68837 ChEBI	pectate	+	degradation
43356	28017 ChEBI	starch	-	degradation
68369	27897 ChEBI	tryptophan	-	energy source	from API 20NE
43356	53424 ChEBI	tween 20	+	degradation
43356	53426 ChEBI	tween 80	+	degradation
68369	16199 ChEBI	urea	-	hydrolysis	from API 20NE

Metabolite production

@ref	Chebi-ID	Metabolite	Production
43356	15688 ChEBI	acetoin
68369	35581 ChEBI	indole		from API 20NE

Metabolite tests

@ref	Chebi-ID	Metabolite	Indole test	Voges-proskauer-test	Methylred-test
43356	15688 ChEBI	acetoin		-
43356	17234 ChEBI	glucose			-
68369	35581 ChEBI	indole	-			from API 20NE

Enzymes

@ref	Value	Activity	Ec
68369	arginine dihydrolase	-	3.5.3.6	from API 20NE
68369	beta-glucosidase	+	3.2.1.21	from API 20NE
43356	catalase	+	1.11.1.6
43356	cytochrome oxidase	+	1.9.3.1
68369	cytochrome oxidase	+	1.9.3.1	from API 20NE
68369	gelatinase	+		from API 20NE
68369	urease	-	3.5.1.5	from API 20NE

Pathway annotation

Computationally determined by

@ref	pathway	enzyme coverage	annotated reactions
66794	biotin biosynthesis	100	4 of 4
66794	UDP-GlcNAc biosynthesis	100	3 of 3
66794	CDP-diacylglycerol biosynthesis	100	2 of 2
66794	sulfopterin metabolism	100	4 of 4
66794	coenzyme A metabolism	100	4 of 4
66794	ppGpp biosynthesis	100	4 of 4
66794	formaldehyde oxidation	100	3 of 3
66794	cis-vaccenate biosynthesis	100	2 of 2
66794	methylglyoxal degradation	100	5 of 5
66794	adipate degradation	100	2 of 2
66794	aminopropanol phosphate biosynthesis	100	2 of 2
66794	palmitate biosynthesis	100	22 of 22
66794	folate polyglutamylation	100	1 of 1
66794	anapleurotic synthesis of oxalacetate	100	1 of 1
66794	aspartate and asparagine metabolism	100	9 of 9
66794	suberin monomers biosynthesis	100	2 of 2
66794	enterobactin biosynthesis	100	3 of 3
66794	photosynthesis	92.86	13 of 14
66794	pentose phosphate pathway	90.91	10 of 11
66794	propionate fermentation	90	9 of 10
66794	Entner Doudoroff pathway	90	9 of 10
66794	threonine metabolism	90	9 of 10
66794	valine metabolism	88.89	8 of 9
66794	chorismate metabolism	88.89	8 of 9
66794	molybdenum cofactor biosynthesis	88.89	8 of 9
66794	serine metabolism	88.89	8 of 9
66794	lipid A biosynthesis	88.89	8 of 9
66794	CO2 fixation in Crenarchaeota	88.89	8 of 9
66794	isoleucine metabolism	87.5	7 of 8
66794	gluconeogenesis	87.5	7 of 8
66794	tetrahydrofolate metabolism	85.71	12 of 14
66794	heme metabolism	85.71	12 of 14
66794	reductive acetyl coenzyme A pathway	85.71	6 of 7
66794	glutathione metabolism	85.71	12 of 14
66794	ubiquinone biosynthesis	85.71	6 of 7
66794	phenylalanine metabolism	84.62	11 of 13
66794	leucine metabolism	84.62	11 of 13
66794	purine metabolism	84.04	79 of 94
66794	NAD metabolism	83.33	15 of 18
66794	cellulose degradation	80	4 of 5
66794	peptidoglycan biosynthesis	80	12 of 15
66794	vitamin K metabolism	80	4 of 5
66794	tryptophan metabolism	78.95	30 of 38
66794	glutamate and glutamine metabolism	78.57	22 of 28
66794	citric acid cycle	78.57	11 of 14
66794	d-mannose degradation	77.78	7 of 9
66794	methionine metabolism	76.92	20 of 26
66794	alanine metabolism	75.86	22 of 29
66794	pyrimidine metabolism	75.56	34 of 45
66794	C4 and CAM-carbon fixation	75	6 of 8
66794	glycogen biosynthesis	75	3 of 4
66794	butanoate fermentation	75	3 of 4
66794	CMP-KDO biosynthesis	75	3 of 4
66794	dTDPLrhamnose biosynthesis	75	6 of 8
66794	acetate fermentation	75	3 of 4
66794	flavin biosynthesis	73.33	11 of 15
66794	vitamin B6 metabolism	72.73	8 of 11
66794	proline metabolism	72.73	8 of 11
66794	histidine metabolism	72.41	21 of 29
66794	propanol degradation	71.43	5 of 7
66794	cardiolipin biosynthesis	71.43	5 of 7
66794	lipid metabolism	70.97	22 of 31
66794	glycolysis	70.59	12 of 17
66794	vitamin B1 metabolism	69.23	9 of 13
66794	L-lactaldehyde degradation	66.67	2 of 3
66794	octane oxidation	66.67	2 of 3
66794	arginine metabolism	66.67	16 of 24
66794	cyanate degradation	66.67	2 of 3
66794	acetoin degradation	66.67	2 of 3
66794	lysine metabolism	64.29	27 of 42
66794	6-hydroxymethyl-dihydropterin diphosphate biosynthesis	62.5	5 of 8
66794	ketogluconate metabolism	62.5	5 of 8
66794	urea cycle	61.54	8 of 13
66794	cysteine metabolism	61.11	11 of 18
66794	non-pathway related	60.53	23 of 38
66794	starch degradation	60	6 of 10
66794	metabolism of amino sugars and derivatives	60	3 of 5
66794	myo-inositol biosynthesis	60	6 of 10
66794	glycogen metabolism	60	3 of 5
66794	lipoate biosynthesis	60	3 of 5
66794	D-cycloserine biosynthesis	60	3 of 5
66794	degradation of aromatic, nitrogen containing compounds	58.33	7 of 12
66794	isoprenoid biosynthesis	57.69	15 of 26
66794	degradation of sugar alcohols	56.25	9 of 16
66794	arachidonic acid metabolism	55.56	10 of 18
66794	d-xylose degradation	54.55	6 of 11
66794	phosphatidylethanolamine bioynthesis	53.85	7 of 13
66794	sulfate reduction	53.85	7 of 13
66794	3-phenylpropionate degradation	53.33	8 of 15
66794	toluene degradation	50	2 of 4
66794	glycolate and glyoxylate degradation	50	3 of 6
66794	cyclohexanol degradation	50	2 of 4
66794	ethanol fermentation	50	1 of 2
66794	quinate degradation	50	1 of 2
66794	phenol degradation	50	10 of 20
66794	tyrosine metabolism	50	7 of 14
66794	ribulose monophosphate pathway	50	1 of 2
66794	androgen and estrogen metabolism	50	8 of 16
66794	carnitine metabolism	50	4 of 8
66794	metabolism of disaccharids	45.45	5 of 11
66794	ascorbate metabolism	45.45	10 of 22
66794	degradation of hexoses	44.44	8 of 18
66794	polyamine pathway	43.48	10 of 23
66794	oxidative phosphorylation	41.76	38 of 91
66794	vitamin B12 metabolism	41.18	14 of 34
66794	3-chlorocatechol degradation	40	2 of 5
66794	glycine metabolism	40	4 of 10
66794	gallate degradation	40	2 of 5
66794	arachidonate biosynthesis	40	2 of 5
66794	glycine betaine biosynthesis	40	2 of 5
66794	ethylmalonyl-CoA pathway	40	2 of 5
66794	bacilysin biosynthesis	40	2 of 5
66794	chlorophyll metabolism	38.89	7 of 18
66794	phenylpropanoid biosynthesis	38.46	5 of 13
66794	cholesterol biosynthesis	36.36	4 of 11
66794	degradation of pentoses	35.71	10 of 28
66794	acetyl CoA biosynthesis	33.33	1 of 3
66794	(5R)-carbapenem carboxylate biosynthesis	33.33	1 of 3
66794	nitrate assimilation	33.33	3 of 9
66794	methane metabolism	33.33	1 of 3
66794	4-hydroxymandelate degradation	33.33	3 of 9
66794	IAA biosynthesis	33.33	1 of 3
66794	sphingosine metabolism	33.33	2 of 6
66794	sulfoquinovose degradation	33.33	1 of 3
66794	pantothenate biosynthesis	33.33	2 of 6
66794	selenocysteine biosynthesis	33.33	2 of 6
66794	coenzyme M biosynthesis	30	3 of 10
66794	benzoyl-CoA degradation	28.57	2 of 7
66794	aclacinomycin biosynthesis	28.57	2 of 7
66794	alginate biosynthesis	25	1 of 4
66794	lactate fermentation	25	1 of 4
66794	vitamin E metabolism	25	1 of 4
66794	catecholamine biosynthesis	25	1 of 4
66794	degradation of sugar acids	24	6 of 25

API 20NE

@ref	Reduction of nitratesNO3	TRP	GLU_ Ferm	ADH (Arg)	URE	ESC	GEL	PNPG	GLU_ Assim	ARA	MNE	MAN	NAG	MAL	GNT	CAP	ADI	MLT	CIT	PAC	OX
685	-	-	-	-	-	+	+	+	+	-	-	-	+	+	-	-	-	+	+	-	+
685	-	-	-	-	-	+	+	+	+	-	+	-	+	+	-	-	-	+	+	-	+

Isolation, sampling and environmental information

Isolation source categories

Cat1	Cat2	Cat3
#Environmental	#Terrestrial	#Soil

Isolation

@ref	Sample type	Geographic location	Country	Country ISO 3 Code	Continent
685	soil	Ontario, Ottawa	Canada	CAN	North America
67771	From soil	Central Experimental Farm Ottawa Ontario Canada	Canada	CAN	North America
45040	Soil	Ontario,Ottawa	Canada	CAN	North America

Taxonmaps

69479

Global distribution of 16S sequence AJ298291 (>99% sequence identity) for Lysobacter from Microbeatlas

Aquatic Samples	116
Soil Samples	486
Animal Samples	135
Plant Samples	290
Total Samples	1027

Interaction and safety

Risk assessment

@ref	Biosafety level	Biosafety level comment
685	1	Risk group (German classification) According to TRBA 466

Sequence information

Genome sequences

@ref	Description	Assembly level	INSDC accession	BV-BRC accession	IMG accession	NCBI tax ID	Score
66792	IMG-taxon 2675903697 annotated assembly for Lysobacter enzymogenes ATCC 29487	scaffold	GCA_900106525	69.16	2675903697	69	52.66

16S sequences

@ref	Description	Accession	Length	NCBI tax ID
685	Lysobacter enzymogenes 16S rRNA gene, strain DSM 2043T	AJ298291	1509	69
124043	Lysobacter enzymogenes genomic DNA containing 16S-23S intergenic spacer region, strain LMG 8762	LM994048	526	69
124043	Lysobacter enzymogenes strain DSM 2043 16S ribosomal RNA gene, partial sequence.	KT851480	1170	69

GC content

@ref	GC-content (mol%)	Method
43356	69-70.1	high performance liquid chromatography (HPLC)

Genome-based predictions

Predictions

Predictions from Deep Learning for Genome Sequence Data. R package version 0.3.1 based on: Lysobacter enzymogenes ATCC 29487
NCBI: GCA_900106525

@ref	Trait	Model	Prediction	Confidence in %	In training data
125439	spore_formation	BacteriaNetⓘ	no	86.00	no
125439	motility	BacteriaNetⓘ	yes	81.60	no
125439	gram_stain	BacteriaNetⓘ	negative	92.00	no
125439	oxygen_tolerance	BacteriaNetⓘ	obligate aerobe	99.20	no

Predictions from bacterial phenotypic traits through improved machine learning using high-quality, curated datasets based on: Lysobacter enzymogenes ATCC 29487
NCBI: GCA_900106525.1

@ref	Trait	Model	Prediction	Confidence in %	In training data
125438	gram-positive	gram-positiveⓘ	no	97.25	yes
125438	anaerobic	anaerobicⓘ	no	97.55	yes
125438	aerobic	aerobicⓘ	yes	82.46	no
125438	spore-forming	spore-formingⓘ	no	87.93	no
125438	thermophilic	thermophileⓘ	no	97.98	yes
125438	flagellated	motile2+ⓘ	yes	68.19	no

Literature

Topic	Title	Authors	Journal	DOI	Year
	Quantitative Analysis of Lysobacter Predation.	Seccareccia I, Kost C, Nett M.	Appl Environ Microbiol	10.1128/aem.01781-15	2015
	Antibiotic-Lysobacter enzymogenes proteases combination as a novel virulence attenuating therapy.	Suaifan GARY, Abdel Rahman DMA, Abu-Odeh AM, Abu Jbara F, Shehadeh MB, Darwish RM.	PLoS One	10.1371/journal.pone.0282705	2023
Genetics	Phylogenomics insights into order and families of Lysobacterales.	Kumar S, Bansal K, Patil PP, Patil PB.	Access Microbiol	10.1099/acmi.0.000015	2019
	Characteristics and Biological Activity of Exopolysaccharide Produced by Lysobacter sp. MMG2 Isolated from the Roots of Tagetes patula.	Kim I, Chhetri G, So Y, Kim J, Seo T.	Microorganisms	10.3390/microorganisms10071257	2022
	Nucleotide sequence and characterization of the gene for secreted alkaline phosphatase from Lysobacter enzymogenes.	Au S, Roy KL, von Tigerstrom RG.	J Bacteriol	10.1128/jb.173.15.4551-4557.1991	1991
	Distribution of multicopy single-stranded DNA among myxobacteria and related species.	Dhundale AR, Furuichi T, Inouye S, Inouye M.	J Bacteriol	10.1128/jb.164.2.914-917.1985	1985
Enzymology	Production of two phosphatases by Lysobacter enzymogenes and purification and characterization of the extracellular enzyme.	von Tigerstrom RG.	Appl Environ Microbiol	10.1128/aem.47.4.693-698.1984	1984
	Heterologous Production of Phenazines in the Biocontrol Agent Lysobacter enzymogenes C3.	Li X, Pan C, Wang H, Shen Y, Li Y, Du L.	J Agric Food Chem	10.1021/acs.jafc.4c09518	2025
Phylogeny	Characterization of a bacterial strain T226 and its efficacy in controlling post-harvest citrus anthracnose.	Wang Q, Song J, Zeng Q, Ye X, Shi G, Hu C.	Front Microbiol	10.3389/fmicb.2025.1678436	2025
Transcriptome	Transcriptomic Analyses of Tomato Exhibiting Induced Resistance to Ralstonia solanacearum by Lysobacter enzymogenes JCK1421.	Park J, Jung H, Jeong T, Park AR, Mannaa M, Lee D, Kim JC, Seo YS.	Plants (Basel)	10.3390/plants14223415	2025
	Mechanism of Lysobacter enzymogenes resistance toward fungi induced by fungal-derived signal alpha-terpinene.	Zhu M, Li Y, Nan F, Wang J, Gao B, Song H, Bian Z, Wang X, Zhu Y, Wang Y.	Appl Environ Microbiol	10.1128/aem.01471-25	2025
	Hfq modulates system-wide regulatory networks controlling biocontrol property in Lysobacter enzymogenes.	Cheng X, Chen W, Zhao Y, Zhao Y, Liu F, Xu G.	Synth Syst Biotechnol	10.1016/j.synbio.2025.08.013	2026
	Unveiling the Role of Diffusible Signal Factor-Family Quorum Sensing Signals in Regulating Behavior of Xanthomonas and Lysobacter.	Li K, Ma C, Xiong C, Zhou X, Mao Y, Wang Y, Liu F.	Phytopathology	10.1094/phyto-07-23-0264-r	2024
	Antifungal Compound from the Predatory Bacterium Lysobacter enzymogenes Inhibits a Plant Pathogenic Fungus by Targeting the AAA ATPase VpVeb1.	Hou R, Li K, Guo B, Zhao Y, Li C, Tang B, Sun W, Wang B, Chen W, Sheng C, Kan J, Zhao Y, Liu F.	J Agric Food Chem	10.1021/acs.jafc.3c06262	2023
	Identification and Biosynthetic Study of the Siderophore Lysochelin in the Biocontrol Agent Lysobacter enzymogenes.	Miller AL, Li S, Eichhorn CD, Zheng Y, Du L.	J Agric Food Chem	10.1021/acs.jafc.3c01250	2023
	Identification of Pyrrole-2-Carboxylic Acid from the Biocontrol Agent Lysobacter Involved in Interactions with Fusarial Fungi.	Jayasekera V, Han Y, Du L.	Microorganisms	10.3390/microorganisms13061202	2025
Genetics	[Effects of organic fertilizer from traditional Chinese medicine residues on growth and soil microbial community of Salvia miltiorrhiza by metagenomic technique].	Wang ZH, Liu S, Yang G, Lu ZY, Zhu RQ, Li Y, Shen Y, Kang LP, Chen ML.	Zhongguo Zhong Yao Za Zhi	10.19540/j.cnki.cjcmm.20231213.101	2024
	Twitching Motility Assays of Lysobacter enzymogenes OH11 Under a Light Microscope.	Wang B, Shao X, Qian G.	Methods Mol Biol	10.1007/978-1-0716-3060-0_19	2023
	The natural polycyclic tetramate macrolactam HSAF inhibit Fusarium graminearum through altering cell membrane integrity by targeting FgORP1.	Chen W, Tang B, Hou R, Sun W, Han C, Guo B, Zhao Y, Li C, Sheng C, Zhao Y, Liu F.	Int J Biol Macromol	10.1016/j.ijbiomac.2024.129744	2024
	Regulatory Effects of Diverse DSF Family Quorum-Sensing Signals in Plant-Associated Bacteria.	Li K, Ma C, Zhou X, Xiong C, Wang B, Wang Y, Liu F.	Mol Plant Microbe Interact	10.1094/mpmi-05-23-0074-cr	2024
	The posttranscriptional regulator CsrA affects multidrug resistance and biocontrol activity in Lysobacter enzymogenes.	Yu M, Zhao Y.	J Appl Microbiol	10.1093/jambio/lxad045	2023
	Biosynthesis of Odd-Carbon Unsaturated Fatty Dicarboxylic Acids Through Engineering the HSAF Biosynthetic Gene in Lysobacter enzymogenes.	Khetrapal V, Dussault P, Du L.	Mol Biotechnol	10.1007/s12033-022-00520-1	2022
	The Role of Phyllosphere Microbes and Viruses in Biocontrol of Pathogenic Fungi.	Bi L, Islam ZF, Chan LH, Hu HW.	Microb Biotechnol	10.1111/1751-7915.70251	2025
	Identification and Characterization of the 28-N-Methyltransferase Involved in HSAF Analogue Biosynthesis.	Luo J, Li X, Wang H, Du L, Shen Y, Li Y.	Biochemistry	10.1021/acs.biochem.2c00575	2022
	Ultrahigh-throughput screening of environmental bacteria for proteolytic activity using droplet-based microfluidics.	Nakamura A, Suzuki Y, Homma N, Shida Y, Sato R, Takaku H, Ogasawara W.	Appl Environ Microbiol	10.1128/aem.00109-25	2025
	Lysobacter enzymogenes antagonizes soilborne bacteria using the type IV secretion system.	Shen X, Wang B, Yang N, Zhang L, Shen D, Wu H, Dong Y, Niu B, Chou SH, Puopolo G, Fan J, Qian G.	Environ Microbiol	10.1111/1462-2920.15662	2021
	A novel and high-efficient method for the preparation of heat-stable antifungal factor from Lysobacter enzymogenes by high-speed counter-current chromatography.	Sun W, Tang B, Dong L, Xu J, Zhao Y, Liu F.	Front Microbiol	10.3389/fmicb.2023.1227244	2023
	Iron ions regulate antifungal HSAF biosynthesis in Lysobacter enzymogenes by manipulating the DNA-binding affinity of the ferric uptake regulator (Fur).	Tang B, Wang B, Xu Z, Hou R, Zhang M, Chen X, Liu Y, Liu F.	Microbiol Spectr	10.1128/spectrum.00617-23	2023
	Efficient direct preparation of antifungal Alteramide B from Lysobacter enzymogenes fermentation broth by macroporous resin adsorption.	Tang B, Chen X, Laborda P, Liu F.	Bioresour Technol	10.1016/j.biortech.2020.124220	2021
Enzymology	Characterization of Lysobacter enzymogenes B25, a potential biological control agent of plant-parasitic nematodes, and its mode of action.	Martinez-Servat S, Pinyol-Escala L, Daura-Pich O, Almazan M, Hernandez I, Lopez-Garcia B, Fernandez C.	AIMS Microbiol	10.3934/microbiol.2023010	2023
	Spectinomycin resistance in Lysobacter enzymogenes is due to its rRNA target but also relies on cell-wall recycling and purine biosynthesis.	Yu M, Zhao Y.	Front Microbiol	10.3389/fmicb.2022.988110	2022
	Characterization of a Disease-Suppressive Isolate of Lysobacter enzymogenes with Broad Antagonistic Activity against Bacterial, Oomycetal and Fungal Pathogens in Different Crops.	Drenker C, El Mazouar D, Bucker G, Weisshaupt S, Wienke E, Koch E, Kunz S, Reineke A, Rondot Y, Linkies A.	Plants (Basel)	10.3390/plants12030682	2023
	Old role with new feature: T2SS ATPase as a cyclic-di-GMP receptor to regulate antibiotic production.	Liu H, Xu G, Guo B, Liu F.	Appl Environ Microbiol	10.1128/aem.00418-24	2024
	Two-step localization driven by peptidoglycan hydrolase in interbacterial predation.	Song H, Zhu Y, Qu Z, Zhu M, Li X, Zhao L, Wang K, Zhang R, Cui L, Li Y, Bian Z, Zhang W, Chen Y, Du L, Wang JL, Zhao X, Deng L, Wang Y.	ISME J	10.1093/ismejo/wraf208	2025
Pathogenicity	Lysobacter enzymogenes LE16 autolysates have potential as biocontrol agents-Lysobacter sp. autolysates as biofungicide.	Chen DM, Yang HJ, Huang JG, Yuan L.	J Appl Microbiol	10.1111/jam.14752	2020
	Type IV secretion system effector sabotages multiple defense systems in a competing bacterium.	Wang B, Xu F, Zhang Z, Shen D, Wang L, Wu H, Yan Q, Cui C, Wang P, Wei Q, Shao X, Wang M, Qian G.	ISME J	10.1093/ismejo/wrae121	2024
	Assembly of an active microbial consortium by engineering compatible combinations containing foreign and native biocontrol bacteria of kiwifruit.	Lin L, Li L, Tao M, Wu Q, Zhou L, Wang B, Wang L, Shao X, Zhong C, Qian G.	Comput Struct Biotechnol J	10.1016/j.csbj.2023.07.021	2023
	Lysobacter enzymogenes Employs Diverse Genes for Inhibiting Hypha Growth and Spore Germination of Soybean Fungal Pathogens.	Yu M, Zhang G, Jiang J, Du L, Zhao Y.	Phytopathology	10.1094/phyto-09-19-0356-r	2020
	Antifungal weapons of Lysobacter, a mighty biocontrol agent.	Lin L, Xu K, Shen D, Chou SH, Gomelsky M, Qian G.	Environ Microbiol	10.1111/1462-2920.15674	2021
	Identification of atypical T4SS effector proteins mediating bacterial defense.	Shen X, Yang Z, Li Z, Xiong D, Liao J, He W, Shen D, Shao X, Niu B, He Y, Gao YG, Qian G.	mLife	10.1002/mlf2.12084	2023
Metabolism	Knockout of Diguanylate Cyclase Genes in Lysobacter enzymogenes to Improve Production of Antifungal Factor and Increase Its Application in Seed Coating.	Ren X, Ren S, Xu G, Dou W, Chou SH, Chen Y, Qian G.	Curr Microbiol	10.1007/s00284-020-01902-x	2020
Pathogenicity	Cell permeability, beta-lactamase activity, and transport contribute to high level of resistance to ampicillin in Lysobacter enzymogenes.	Yu M, Zhao Y.	Appl Microbiol Biotechnol	10.1007/s00253-019-10266-7	2020
	Characterization of soybean chitinase genes induced by rhizobacteria involved in the defense against Fusarium oxysporum.	Chen JY, Sang H, Chilvers MI, Wu CH, Chang HX.	Front Plant Sci	10.3389/fpls.2024.1341181	2024
Metabolism	Optimization of culture conditions for promoting heat-stable antifungal factor production level in Lysobacter enzymogenes.	Wang C, Xu H, Zhang Y, Wu S, Chen D, Qian G, Hu B, Fan J.	FEMS Microbiol Lett	10.1093/femsle/fnz007	2019
Metabolism	A novel heterologous expression strategy for the quorum-quenching enzyme MomL in Lysobacter enzymogenes to the inhibit pathogenicity of Pectobacterium.	Wang Y, Feng T, Li H, Yu Y, Han Y, Zhang J, Li X, Li Y, Zhang XH.	Appl Microbiol Biotechnol	10.1007/s00253-019-10166-w	2019
	Microbial Consortium of Streptomyces spp. from Mining Environments Enhances Phytoremediation Potential of Lemna minor L.	Djebaili R, Farda B, Gialdini O, Vaccarelli I, Rezaee Danesh Y, Pellegrini M.	Plants (Basel)	10.3390/plants14223467	2025
	Lysobacter enzymogenes prevents Phytophthora infection by inhibiting pathogen growth and eliciting plant immune responses.	Lin L, Yang Z, Tao M, Shen D, Cui C, Wang P, Wang L, Jing M, Qian G, Shao X.	Front Plant Sci	10.3389/fpls.2023.1116147	2023
	ClpP mediates antagonistic interaction of Lysobacter enzymogenes with a crop fungal pathogen	Yang M, Ren S, Shen D, Chou SH, Qian G.	Biol Control		2019
	Control of Wheat Fusarium Head Blight by Heat-Stable Antifungal Factor (HSAF) from Lysobacter enzymogenes.	Zhao Y, Cheng C, Jiang T, Xu H, Chen Y, Ma Z, Qian G, Liu F.	Plant Dis	10.1094/pdis-09-18-1517-re	2019
Metabolism	A non-flagellated, predatory soil bacterium reprograms a chemosensory system to control antifungal antibiotic production via cyclic di-GMP signalling.	Xu K, Shen D, Han S, Chou SH, Qian G.	Environ Microbiol	10.1111/1462-2920.15191	2021
Metabolism	Improving the production of a novel antifungal alteramide B in Lysobacter enzymogenes OH11 by strengthening metabolic flux and precursor supply.	Tang B, Laborda P, Sun C, Xu G, Zhao Y, Liu F.	Bioresour Technol	10.1016/j.biortech.2018.10.085	2019
	Increment in protease activity of Lysobacter enzymogenes strain by ultra violet radiation.	Kalahroudi RJ, Valizadeh V, Atyabi SM, Keramati M, Cohan RA, Aghai A, Norouzian D.	Iran J Microbiol	10.18502/ijm.v12i6.5035	2020
Metabolism	Spermidine plays a significant role in stabilizing a master transcription factor Clp to promote antifungal activity in Lysobacter enzymogenes.	Zhao Y, Zhang T, Ning Y, Shen D, Yang N, Li Y, Chou SH, Yang L, Qian G.	Appl Microbiol Biotechnol	10.1007/s00253-018-09596-9	2019
Metabolism	Two direct gene targets contribute to Clp-dependent regulation of type IV pilus-mediated twitching motility in Lysobacter enzymogenes OH11.	Chen J, Shen D, Odhiambo BO, Xu D, Han S, Chou SH, Qian G.	Appl Microbiol Biotechnol	10.1007/s00253-018-9196-x	2018
	Separation of Heat-Stable Antifungal Factor From Lysobacter enzymogenes Fermentation Broth via Photodegradation and Macroporous Resin Adsorption.	Tang B, Wu L, Wang J, Sun W, Zhao Y, Liu F.	Front Microbiol	10.3389/fmicb.2021.663065	2021
	Insights into the distinct cooperation between the transcription factor Clp and LeDSF signaling in the regulation of antifungal factors in Lysobacter enzymogenes OH11	Xu G, Shi X, Wang R, Xu H, Du L, Chou SH, Liu H, Liu Y, Qian G, Liu F.	Biol Control	10.1016/j.biocontrol.2016.08.006	2018
	A new bacteriolytic amidase Ami of Lysobacter capsici XL1.	Kudryakova I, Afoshin A, Tarlachkov S, Pavlenko S, Suzina N, Shishkova N, Leontyevskaya E, Leontyevskaya N.	Sci Rep	10.1038/s41598-025-07691-2	2025
	Response of Pine Rhizosphere Microbiota to Foliar Treatment with Resistance-Inducing Bacteria against Pine Wilt Disease.	Han G, Mannaa M, Kim N, Jeon HW, Jung H, Lee HH, Kim J, Park J, Park AR, Kim JC, Seo YS.	Microorganisms	10.3390/microorganisms9040688	2021
	A Novel and Efficient Platform for Discovering Noncanonical Quorum-Quenching Proteins.	Liao J, Li Z, Xiong D, Shen D, Wang L, Shao X, Li T, Qian G.	Microbiol Spectr	10.1128/spectrum.03437-22	2023
Metabolism	Type IV pilus biogenesis genes and their roles in biofilm formation in the biological control agent Lysobacter enzymogenes OH11.	Xia J, Chen J, Chen Y, Qian G, Liu F.	Appl Microbiol Biotechnol	10.1007/s00253-017-8619-4	2018
	Functional divergence of flagellar type III secretion system: A case study in a non-flagellated, predatory bacterium.	Fulano AM, Shen D, Zhang EH, Shen X, Chou SH, Minamino T, Puopolo G, Qian G.	Comput Struct Biotechnol J	10.1016/j.csbj.2020.10.029	2020
	Polycyclic Tetramate Macrolactams-A Group of Natural Bioactive Metallophores.	Ding L, Zhang SD, Haidar AK, Bajimaya M, Guo Y, Larsen TO, Gram L.	Front Chem	10.3389/fchem.2021.772858	2021
Metabolism	LeTetR Positively Regulates 3-Hydroxylation of the Antifungal HSAF and Its Analogs in Lysobacter enzymogenes OH11.	Yu L, Khetrapal V, Liu F, Du L.	Molecules	10.3390/molecules25102286	2020
	Diguanylate Cyclase and Phosphodiesterase Interact To Maintain the Specificity of Cyclic di-GMP Signaling in the Regulation of Antibiotic Synthesis in Lysobacter enzymogenes.	Xu G, Zhou L, Qian G, Liu F.	Appl Environ Microbiol	10.1128/aem.01895-21	2022
Metabolism	An Antifungal Polycyclic Tetramate Macrolactam, Heat-Stable Antifungal Factor (HSAF), Is a Novel Oxidative Stress Modulator in Lysobacter enzymogenes.	Yu L, Li H, Zhou Z, Liu F, Du L.	Appl Environ Microbiol	10.1128/aem.03105-20	2021
	Soil microbiome bacteria protect plants against filamentous fungal infections via intercellular contacts.	Lin L, Shen D, Shao X, Yang Y, Li L, Zhong C, Jiang J, Wang M, Qian G.	Proc Natl Acad Sci U S A	10.1073/pnas.2418766122	2025
Metabolism	Evidence of an Unidentified Extracellular Heat-Stable Factor Produced by Lysobacter enzymogenes (OH11) that Degrade Fusarium graminearum PH1 Hyphae.	Odhiambo BO, Xu G, Qian G, Liu F.	Curr Microbiol	10.1007/s00284-017-1206-1	2017
	Draft Genome Sequence and Assembly of a Lysobacter enzymogenes Strain with Biological Control Activity against Root Knot Nematodes.	Hernandez I, Fernandez C.	Genome Announc	10.1128/genomea.00271-17	2017
	Soil bacterium manipulates antifungal weapons by sensing intracellular type IVA secretion system effectors of a competitor.	Wang B, Zhang Z, Xu F, Yang Z, Li Z, Shen D, Wang L, Wu H, Li T, Yan Q, Wei Q, Shao X, Qian G.	ISME J	10.1038/s41396-023-01533-7	2023
	ChpA Controls Twitching Motility and Broadly Affects Gene Expression in the Biological Control Agent Lysobacter enzymogenes.	Zhou M, Shen D, Xu G, Liu F, Qian G.	Curr Microbiol	10.1007/s00284-017-1202-5	2017
	5-Methylindole kills various bacterial pathogens and potentiates aminoglycoside against methicillin-resistant Staphylococcus aureus.	Li Z, Sun F, Fu X, Chen Y.	PeerJ	10.7717/peerj.14010	2022
Enzymology	Specific detection of Lysobacter antibioticus strains in agricultural soil using PCR and real-time PCR.	Lina F, Ting W, Lanfang W, Jun Y, Qi L, Yating W, Xing W, Guanghai J.	FEMS Microbiol Lett	10.1093/femsle/fny219	2018
	Construction of a hybrid gene cluster to reveal coupled ring formation-hydroxylation in the biosynthesis of HSAF and analogues from Lysobacter enzymogenes.	Li X, Wang H, Li Y, Du L.	Medchemcomm	10.1039/c9md00154a	2019
Metabolism	4-Hydroxybenzoic acid is a diffusible factor that connects metabolic shikimate pathway to the biosynthesis of a unique antifungal metabolite in Lysobacter enzymogenes.	Su Z, Chen H, Wang P, Tombosa S, Du L, Han Y, Shen Y, Qian G, Liu F.	Mol Microbiol	10.1111/mmi.13619	2017
	Functional diversity of c-di-GMP receptors in prokaryotic and eukaryotic systems.	Khan F, Jeong GJ, Tabassum N, Kim YM.	Cell Commun Signal	10.1186/s12964-023-01263-5	2023
Metabolism	A YajQ-LysR-like, cyclic di-GMP-dependent system regulating biosynthesis of an antifungal antibiotic in a crop-protecting bacterium, Lysobacter enzymogenes.	Han S, Shen D, Wang YC, Chou SH, Gomelsky M, Gao YG, Qian G.	Mol Plant Pathol	10.1111/mpp.12890	2020
	First report of a tropical Lysobacter enzymogenes producing bifunctional endoglucanase activity towards carboxymethylcellulose and chitosan	Saraihom S, Kobayashi DY, Lotrakul P, Prasongsuk S, Eveleigh DE, Punnapayak H.	Ann Microbiol		2016
Metabolism	Direct Regulation of Extracellular Chitinase Production by the Transcription Factor LeClp in Lysobacter enzymogenes OH11.	Xu H, Chen H, Shen Y, Du L, Chou SH, Liu H, Qian G, Liu F.	Phytopathology	10.1094/phyto-01-16-0001-r	2016
Metabolism	Coordinated control of the type IV pili and c-di-GMP-dependent antifungal antibiotic production in Lysobacter by the response regulator PilR.	Xu K, Shen D, Yang N, Chou SH, Gomelsky M, Qian G.	Mol Plant Pathol	10.1111/mpp.13046	2021
Metabolism	The predatory soil bacterium Lysobacter reprograms quorum sensing system to regulate antifungal antibiotic production in a cyclic-di-GMP-independent manner.	Li K, Xu G, Wang B, Wu G, Hou R, Liu F.	Commun Biol	10.1038/s42003-021-02660-7	2021
	Exploring bioactive molecules released during inter- and intraspecific competition: A paradigm for novel antiparasitic drug discovery and design for human use.	Ruenchit P.	Curr Res Parasitol Vector Borne Dis	10.1016/j.crpvbd.2025.100256	2025
	The Wsp chemosensory system modulates c-di-GMP-dependent biofilm formation by integrating DSF quorum sensing through the WspR-RpfG complex in Lysobacter.	Xu K, Wang L, Xiong D, Chen H, Tong X, Shao X, Li T, Qian G.	NPJ Biofilms Microbiomes	10.1038/s41522-022-00365-1	2022
Enzymology	Two forms of phosphomannomutase in gammaproteobacteria: The overlooked membrane-bound form of AlgC is required for twitching motility of Lysobacter enzymogenes.	Qian G, Fei S, Galperin MY.	Environ Microbiol	10.1111/1462-2920.14615	2019
	Loss of Flagella-Related Genes Enables a Nonflagellated, Fungal-Predating Bacterium To Strengthen the Synthesis of an Antifungal Weapon.	Xiong D, Yang Z, He X, He W, Shen D, Wang L, Lin L, Murero A, Minamino T, Shao X, Qian G.	Microbiol Spectr	10.1128/spectrum.04149-22	2023
Metabolism	PilG is Involved in the Regulation of Twitching Motility and Antifungal Antibiotic Biosynthesis in the Biological Control Agent Lysobacter enzymogenes.	Zhou X, Qian G, Chen Y, Du L, Liu F, Yuen GY.	Phytopathology	10.1094/phyto-12-14-0361-r	2015
Enzymology	Bioactive Polycyclic Tetramate Macrolactams from Lysobacter enzymogenes and Their Absolute Configurations by Theoretical ECD Calculations.	Xu L, Wu P, Wright SJ, Du L, Wei X.	J Nat Prod	10.1021/acs.jnatprod.5b00099	2015
Phylogeny	The combinations Lysobacter enzymogenes subsp. enzymogenes Christensen and Cook 1978, L. enzymogenes subsp. cookii Christensen 1978 and Streptococcus casseliflavus (Mundt and Graham 1968) Vaughan et al. 1979 were in accordance with the International Code of Nomenclature of Bacteria at the time of publication in the International Journal of Systematic Bacteriology, but are not to be considered to be included on the Approved Lists of Bacterial Names. Opinion 95: Judicial Commission of the International Committee on Systematics of Prokaryotes.	Tindall BJ.	Int J Syst Evol Microbiol	10.1099/ijs.0.069211-0	2014
	Clp is a "busy" transcription factor in the bacterial warrior, Lysobacter enzymogenes.	Xu K, Lin L, Shen D, Chou SH, Qian G.	Comput Struct Biotechnol J	10.1016/j.csbj.2021.06.020	2021
Metabolism	LetR is a TetR family transcription factor from Lysobacter controlling antifungal antibiotic biosynthesis.	Wang P, Chen H, Qian G, Liu F.	Appl Microbiol Biotechnol	10.1007/s00253-017-8117-8	2017
	A cell-cell communication signal from Enterobacter cloacae interfering with the signaling systems and virulence in Shigella sonnei.	Chen X, Wang M, Zhao Z, Ling X, Peng G, Cui B, Wang Q, Gu B, Deng Y.	Appl Environ Microbiol	10.1128/aem.00510-25	2025
Metabolism	Outer Membrane Vesicle-Mediated Codelivery of the Antifungal HSAF Metabolites and Lytic Polysaccharide Monooxygenase in the Predatory Lysobacter enzymogenes.	Yue H, Jiang J, Taylor AJ, Leite AL, Dodds ED, Du L.	ACS Chem Biol	10.1021/acschembio.1c00260	2021
Metabolism	Systematic optimization for production of the anti-MRSA antibiotics WAP-8294A in an engineered strain of Lysobacter enzymogenes.	Chen X, Li S, Yu L, Miller A, Du L.	Microb Biotechnol	10.1111/1751-7915.13484	2019
Metabolism	Two Functional Fatty Acyl Coenzyme A Ligases Affect Free Fatty Acid Metabolism To Block Biosynthesis of an Antifungal Antibiotic in Lysobacter enzymogenes.	Li K, Hou R, Xu H, Wu G, Qian G, Wang H, Liu F.	Appl Environ Microbiol	10.1128/aem.00309-20	2020
	Fighting Tomato Fungal Diseases with a Biocontrol Product Based on Amoeba Lysate.	Troussieux S, Gilgen A, Souche JL.	Plants (Basel)	10.3390/plants12203603	2023
	Spermidine-Regulated Biosynthesis of Heat-Stable Antifungal Factor (HSAF) in Lysobacter enzymogenes OH11.	Chen Y, Yu L, Liu F, Du L.	Front Microbiol	10.3389/fmicb.2018.02984	2018
	The Homologous Components of Flagellar Type III Protein Apparatus Have Acquired a Novel Function to Control Twitching Motility in a Non-Flagellated Biocontrol Bacterium.	Fulano AM, Shen D, Kinoshita M, Chou SH, Qian G.	Biomolecules	10.3390/biom10050733	2020
Metabolism	Atomic resolution structure of a lysine-specific endoproteinase from Lysobacter enzymogenes suggests a hydroxyl group bound to the oxyanion hole.	Asztalos P, Muller A, Holke W, Sobek H, Rudolph MG.	Acta Crystallogr D Biol Crystallogr	10.1107/s1399004714008463	2014
	Benchmarking of Quantitative Proteomics Workflows for Limited Proteolysis Mass Spectrometry.	Koudelka T, Bassot C, Piazza I.	Mol Cell Proteomics	10.1016/j.mcpro.2025.100945	2025
	Dual regulatory role of cyclic di-GMP via the DgcY/HhmR complex in salt response of Halomonas hydrothermalis Y2.	Zhang Y, Wang W, Liu Y, Li C, Liu J, Feng L, Gao Y, Peng Y, Wang W, Li C, Xu P, Yang C.	mBio	10.1128/mbio.01498-25	2025
	Glucoselipid Biosurfactant Biosynthesis Operon of Rouxiella badensis DSM 100043^T: Screening, Identification, and Heterologous Expression in Escherichia coli.	Harahap AFP, Treinen C, Zyl LJV, Williams WT, Conrad J, Pfannstiel J, Klaiber I, Grether J, Hiller E, Vahidinasab M, Perino EHB, Lilge L, Burger A, Trindade M, Hausmann R.	Microorganisms	10.3390/microorganisms13071664	2025
Metabolism	Interspecies and Intraspecies Signals Synergistically Regulate Lysobacter enzymogenes Twitching Motility.	Feng T, Han Y, Li B, Li Z, Yu Y, Sun Q, Li X, Du L, Zhang XH, Wang Y.	Appl Environ Microbiol	10.1128/aem.01742-19	2019
	Vorinostat Treatment of Gastric Cancer Cells Leads to ROS-Induced Cell Inhibition and a Complex Pattern of Molecular Alterations in Nrf2-Dependent Genes.	Lorenz L, Zenz T, Oliinyk D, Meier-Rosar F, Jenke R, Aigner A, Buch T.	Pharmaceuticals (Basel)	10.3390/ph17081080	2024
Genetics	Metabolomic and genomic insights into Micromonospora carbonacea subsp. caeruleus for anti-colorectal compound.	Kongsaya T, Emthomya N, Ngamcharungchit C, Aroonsri A, Uawisetwathana U, Pruksatrakul T, Euanorasetr J, Intra B.	Appl Microbiol Biotechnol	10.1007/s00253-025-13427-z	2025
	Biological soil disinfestation compatible with renewable energy production for sustainable agriculture.	Chen S, Hirano T, Hayashi Y, Tamura H.	J Pestic Sci	10.1584/jpestics.d22-010	2022
	Functionality and translation fidelity characterization of mRNA vaccines using platform based mass spectrometry detection.	Stiving AQ, Roose BW, Tubbs C, Haverick M, Gruber A, Rustandi RR, Kuiper J, Schombs M, Schuessler H, Li X.	NPJ Vaccines	10.1038/s41541-025-01082-4	2025
	Metabolomic Analyses Reveal That IAA from Serratia marcescens Lkbn100 Promotes Plant Defense during Infection of Fusarium graminearum in Sorghum.	Yan J, Qi N, Xu J, Hu L, Jiang Y, Bai Y.	Plants (Basel)	10.3390/plants13162184	2024
	Aerospace Technology Improves Fermentation Potential of Microorganisms.	Chi Y, Wang X, Li F, Zhang Z, Tan P.	Front Microbiol	10.3389/fmicb.2022.896556	2022
	Wheat Seed Coating with Streptomyces sp. Strain DEF39 Spores Protects against Fusarium Head Blight.	Mattei V, Motta A, Saracchi M, Kunova A, Cortesi P, Pizzatti C, Pasquali M.	Microorganisms	10.3390/microorganisms10081536	2022
Metabolism	Efficient production of heat-stable antifungal factor through integrating statistical optimization with a two-stage temperature control strategy in Lysobacter enzymogenes OH11.	Tang B, Sun C, Zhao Y, Xu H, Xu G, Liu F.	BMC Biotechnol	10.1186/s12896-018-0478-2	2018
	Exploration of the Biocontrol Activity of Bacillus atrophaeus Strain HF1 against Pear Valsa Canker Caused by Valsa pyri.	Yuan H, Shi B, Wang Z, Qin G, Hou H, Tu H, Wang L.	Int J Mol Sci	10.3390/ijms242015477	2023
Metabolism	LesR is a novel upstream regulator that controls downstream Clp expression to modulate antibiotic HSAF biosynthesis and cell aggregation in Lysobacter enzymogenes OH11.	Xu H, Wang R, Zhao Y, Fu ZQ, Qian G, Liu F.	Microb Cell Fact	10.1186/s12934-017-0818-2	2017
	Tetracycline induces wsp operon expression to promote biofilm formation in Pseudomonas putida.	Mu K, He M, Chen H, Liu T, Fan Y, Tao Y, Feng H, Huang Q, Xiao Y, Chen W.	Appl Environ Microbiol	10.1128/aem.01071-24	2025
	Novel indole-mediated potassium ion import system confers a survival advantage to the Xanthomonadaceae family.	Zhu Y, Han Y, Liu G, Bian Z, Yan X, Li Y, Long H, Yu G, Wang Y.	ISME J	10.1038/s41396-022-01219-6	2022
	Bacterial quorum sensing quenching activity of Lysobacter leucyl aminopeptidase acts by interacting with autoinducer synthase.	Liao J, Shen D, Lin L, Chen H, Jin Y, Chou SH, Yu XQ, Li T, Qian G.	Comput Struct Biotechnol J	10.1016/j.csbj.2021.11.017	2021
	Lsp family proteins regulate antibiotic biosynthesis in Lysobacter enzymogenes OH11.	Wang R, Xu H, Zhao Y, Zhang J, Yuen GY, Qian G, Liu F.	AMB Express	10.1186/s13568-017-0421-2	2017
Pathogenicity	Biosynthesis of the Polycyclic System in the Antifungal HSAF and Analogues from Lysobacter enzymogenes.	Li Y, Wang H, Liu Y, Jiao Y, Li S, Shen Y, Du L.	Angew Chem Int Ed Engl	10.1002/anie.201802488	2018
Metabolism	Indole-Induced Reversion of Intrinsic Multiantibiotic Resistance in Lysobacter enzymogenes.	Han Y, Wang Y, Yu Y, Chen H, Shen Y, Du L.	Appl Environ Microbiol	10.1128/aem.00995-17	2017
	PlzR regulates type IV pili assembly in Pseudomonas aeruginosa via PilZ binding.	Hendrix H, Itterbeek A, Longin H, Delanghe L, Vriens E, Vallino M, Lammens EM, Haque F, Yusuf A, Noben JP, Boon M, Koch MD, van Noort V, Lavigne R.	Nat Commun	10.1038/s41467-024-52732-5	2024
Transcriptome	Evaluating the Mode of Antifungal Action of Heat-Stable Antifungal Factor (HSAF) in Neurospora crassa.	Liu X, Jiang X, Sun H, Du J, Luo Y, Huang J, Qin L.	J Fungi (Basel)	10.3390/jof8030252	2022
Enzymology	Genetic Basis and Expression Pattern Indicate the Biocontrol Potential and Soil Adaption of Lysobacter capsici CK09.	Yang P, Qu C, Yuan M, Xi B, Jia X, Zhang B, Zhang L.	Microorganisms	10.3390/microorganisms11071768	2023
Metabolism	Heterologous production of active form of beta-lytic protease by Bacillus subtilis and improvement of staphylolytic activity by protein engineering.	Hioki T, Yamashita D, Tohata M, Endo K, Kawahara A, Okuda M.	Microb Cell Fact	10.1186/s12934-021-01724-x	2021
Metabolism	An intrinsic mechanism for coordinated production of the contact-dependent and contact-independent weapon systems in a soil bacterium.	Yang M, Ren S, Shen D, Yang N, Wang B, Han S, Shen X, Chou SH, Qian G.	PLoS Pathog	10.1371/journal.ppat.1008967	2020
Pathogenicity	Vesicular Delivery of the Antifungal Antibiotics of Lysobacter enzymogenes C3.	Meers PR, Liu C, Chen R, Bartos W, Davis J, Dziedzic N, Orciuolo J, Kutyla S, Pozo MJ, Mithrananda D, Panzera D, Wang S.	Appl Environ Microbiol	10.1128/aem.01353-18	2018
	Genetic Insights and Molecular Breeding Approaches for Downy Mildew Resistance in Cucumber (Cucumis sativus L.): Current Progress and Future Prospects.	Mirzwa-Mroz E, Zieniuk B, Yin Z, Pawelkowicz M.	Int J Mol Sci	10.3390/ijms252312726	2024
Metabolism	Unusual acylation of chloramphenicol in Lysobacter enzymogenes, a biocontrol agent with intrinsic resistance to multiple antibiotics.	Zhang W, Huffman J, Li S, Shen Y, Du L.	BMC Biotechnol	10.1186/s12896-017-0377-y	2017
	A response regulator controls Acinetobacter baumannii virulence by acting as an indole receptor.	Cui B, Guo Q, Li X, Song S, Wang M, Wang G, Yan A, Zhou J, Deng Y.	PNAS Nexus	10.1093/pnasnexus/pgad274	2023
	Diffusible signal factors (DSFs) bind and repress VirF, the leading virulence activator of Shigella flexneri.	Trirocco R, Pasqua M, Tramonti A, Colonna B, Paiardini A, Prosseda G.	Sci Rep	10.1038/s41598-023-40023-w	2023
Transcriptome	Transcriptional and Antagonistic Responses of Biocontrol Strain Lysobacter enzymogenes OH11 to the Plant Pathogenic Oomycete Pythium aphanidermatum.	Zhao Y, Qian G, Chen Y, Du L, Liu F.	Front Microbiol	10.3389/fmicb.2017.01025	2017
Metabolism	OX4 Is an NADPH-Dependent Dehydrogenase Catalyzing an Extended Michael Addition Reaction To Form the Six-Membered Ring in the Antifungal HSAF.	Li X, Wang H, Shen Y, Li Y, Du L.	Biochemistry	10.1021/acs.biochem.9b00280	2019
Genetics	Genome Mining of Marine-Derived Streptomyces sp. SCSIO 40010 Leads to Cytotoxic New Polycyclic Tetramate Macrolactams.	Liu W, Zhang W, Jin H, Zhang Q, Chen Y, Jiang X, Zhang G, Zhang L, Zhang W, She Z, Zhang C.	Mar Drugs	10.3390/md17120663	2019
Metabolism	Involvement of both PKS and NRPS in antibacterial activity in Lysobacter enzymogenes OH11.	Zhang J, Du L, Liu F, Xu F, Hu B, Venturi V, Qian G.	FEMS Microbiol Lett	10.1111/1574-6968.12457	2014
	Caenorhabditis elegans RIG-I-like receptor DRH-1 signals via CARDs to activate antiviral immunity in intestinal cells.	Batachari LE, Dai AY, Troemel ER.	Proc Natl Acad Sci U S A	10.1073/pnas.2402126121	2024
	Specific detection of Lysobacter enzymogenes (Christensen and Cook 1978) strain 3.1T8 with TaqMan PCR.	Nijhuis EH, Pastoor R, Postma J.	J Appl Microbiol	10.1111/j.1365-2672.2009.04519.x	2010
	Adapting the inoculation methods of kiwifruit canker disease to identify efficient biocontrol bacteria from branch microbiome.	Shao X, Wu Q, Li L, He W, He X, Cheng D, Murero A, Lin L, Wang L, Zhong C, Huang L, Qian G.	Mol Plant Pathol	10.1111/mpp.13399	2024
Metabolism	Heat-Stable Antifungal Factor (HSAF) Biosynthesis in Lysobacter enzymogenes Is Controlled by the Interplay of Two Transcription Factors and a Diffusible Molecule.	Su Z, Han S, Fu ZQ, Qian G, Liu F.	Appl Environ Microbiol	10.1128/aem.01754-17	2018
	Roles of a solo LuxR in the biological control agent Lysobacter enzymogenes strain OH11.	Qian G, Xu F, Venturi V, Du L, Liu F.	Phytopathology	10.1094/phyto-07-13-0188-r	2014
	Activation of a Cryptic Gene Cluster in Lysobacter enzymogenes Reveals a Module/Domain Portable Mechanism of Nonribosomal Peptide Synthetases in the Biosynthesis of Pyrrolopyrazines.	Li S, Wu X, Zhang L, Shen Y, Du L.	Org Lett	10.1021/acs.orglett.7b01611	2017
Metabolism	Hfq regulates antibacterial antibiotic biosynthesis and extracellular lytic-enzyme production in Lysobacter enzymogenes OH11.	Xu G, Zhao Y, Du L, Qian G, Liu F.	Microb Biotechnol	10.1111/1751-7915.12246	2015
	Use of the tetrazolium salt MTT to measure cell viability effects of the bacterial antagonist Lysobacter enzymogenes on the filamentous fungus Cryphonectria parasitica.	Patel N, Oudemans PV, Hillman BI, Kobayashi DY.	Antonie Van Leeuwenhoek	10.1007/s10482-013-9907-3	2013
	A survey of elastase-producing bacteria and characteristics of the most potent producer, Priestia megaterium gasm32.	AlShaikh-Mubarak GA, Kotb E, Alabdalall AH, Aldayel MF.	PLoS One	10.1371/journal.pone.0282963	2023
	Exploring the potential of endophytes and their metabolites for bio-control activity.	Sharma A, Kaushik N, Sharma A, Marzouk T, Djebali N.	3 Biotech	10.1007/s13205-022-03321-0	2022
Enzymology	Transcriptomic Analysis Followed by the Isolation of Extracellular Bacteriolytic Proteases from Lysobacter capsici VKM B-2533^T.	Afoshin A, Kudryakova I, Tarlachkov S, Leontyevskaya E, Zelenov D, Rudenko P, Leontyevskaya Vasilyeva N.	Int J Mol Sci	10.3390/ijms241411652	2023
Phylogeny	Exploring the Evolutionary History of Kinetic Stability in the alpha-Lytic Protease Family.	Nixon CF, Lim SA, Sailer ZR, Zheludev IN, Gee CL, Kelch BA, Harms MJ, Marqusee S.	Biochemistry	10.1021/acs.biochem.0c00720	2021
	Characterization of the Soil Bacterial Community from Selected Boxwood Gardens across the United States.	Li X, Kong P, Daughtrey M, Kosta K, Schirmer S, Howle M, Likins M, Hong C.	Microorganisms	10.3390/microorganisms10081514	2022
	Stimulants of Toll-like receptors 2 and 4 are elevated in saliva of periodontitis patients compared with healthy subjects.	Lappin DF, Sherrabeh S, Erridge C.	J Clin Periodontol	10.1111/j.1600-051x.2011.01702.x	2011
Phylogeny	Lysobacter enzymogenes subsp. enzymogenes Christensen and Cook 1978, L. enzymogenes subsp. cookii Christensen 1978 and Streptococcus casseliflavus (Mundt and Graham 1968) Vaughan et al. 1978 should have been cited in the Approved Lists of Bacterial Names. Request for an opinion.	Tindall BJ, Euzeby JP.	Int J Syst Evol Microbiol	10.1099/ijs.0.64339-0	2006
	Investigating Antibody Reactivity to the Intestinal Microbiome in Severe Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): A Feasibility Study.	Seton KA, Defernez M, Telatin A, Tiwari SK, Savva GM, Hayhoe A, Noble A, de Carvalho-KoK ALS, James SA, Bansal A, Wileman T, Carding SR.	Int J Mol Sci	10.3390/ijms242015316	2023
	XanFur, a novel Fur protein induced by H₂O₂, positively regulated by the global transcriptional regulator Clp and required for the full virulence of Xanthomonas oryzae pv. oryzae in rice.	Zhang Y-Q, Song X-Y, Liu F.	Microbiol Spectr	10.1128/spectrum.01187-23	2023
Metabolism	Transcriptomic analysis reveals new regulatory roles of Clp signaling in secondary metabolite biosynthesis and surface motility in Lysobacter enzymogenes OH11.	Wang Y, Zhao Y, Zhang J, Zhao Y, Shen Y, Su Z, Xu G, Du L, Huffman JM, Venturi V, Qian G, Liu F.	Appl Microbiol Biotechnol	10.1007/s00253-014-6072-1	2014
	Discovery of Highly Active Recombinant PNGase H⁺ Variants Through the Rational Exploration of Unstudied Acidobacterial Genomes.	Guo RR, Comamala G, Yang HH, Gramlich M, Du YM, Wang T, Zeck A, Rand KD, Liu L, Voglmeir J.	Front Bioeng Biotechnol	10.3389/fbioe.2020.00741	2020
	PilG and PilH antagonistically control flagellum-dependent and pili-dependent motility in the phytopathogen Xanthomonas campestris pv. campestris.	Qi YH, Huang L, Liu GF, Leng M, Lu GT.	BMC Microbiol	10.1186/s12866-020-1712-3	2020
Metabolism	Identification of a small molecule signaling factor that regulates the biosynthesis of the antifungal polycyclic tetramate macrolactam HSAF in Lysobacter enzymogenes.	Han Y, Wang Y, Tombosa S, Wright S, Huffman J, Yuen G, Qian G, Liu F, Shen Y, Du L.	Appl Microbiol Biotechnol	10.1007/s00253-014-6120-x	2015
	A 4-Hydroxybenzoic Acid-Mediated Signaling System Controls the Physiology and Virulence of Shigella sonnei.	Wang M, Zeng J, Zhu Y, Chen X, Guo Q, Tan H, Cui B, Song S, Deng Y.	Microbiol Spectr	10.1128/spectrum.04835-22	2023
Phylogeny	Stenotrophomonas and Lysobacter: ubiquitous plant-associated gamma-proteobacteria of developing significance in applied microbiology.	Hayward AC, Fegan N, Fegan M, Stirling GR.	J Appl Microbiol	10.1111/j.1365-2672.2009.04471.x	2010
	Lysobacter enzymogenes uses two distinct cell-cell signaling systems for differential regulation of secondary-metabolite biosynthesis and colony morphology.	Qian G, Wang Y, Liu Y, Xu F, He YW, Du L, Venturi V, Fan J, Hu B, Liu F.	Appl Environ Microbiol	10.1128/aem.01841-13	2013
	Antagonistic Strain Bacillus amyloliquefaciens XZ34-1 for Controlling Bipolaris sorokiniana and Promoting Growth in Wheat.	Yi Y, Shan Y, Liu S, Yang Y, Liu Y, Yin Y, Hou Z, Luan P, Li R.	Pathogens	10.3390/pathogens10111526	2021
Metabolism	Facile method for site-specific gene integration in Lysobacter enzymogenes for yield improvement of the anti-MRSA antibiotics WAP-8294A and the antifungal antibiotic HSAF.	Wang Y, Qian G, Liu F, Li YZ, Shen Y, Du L.	ACS Synth Biol	10.1021/sb4000806	2013
	Antibacterial and antibiofilm effects of Pseudomonas aeruginosa derived outer membrane vesicles against Streptococcus mutans.	Gurunathan S, Thangaraj P, Das J, Kim JH.	Heliyon	10.1016/j.heliyon.2023.e22606	2023
Pathogenicity	Bacterial Quorum-Sensing Signal DSF Inhibits LPS-Induced Inflammations by Suppressing Toll-like Receptor Signaling and Preventing Lysosome-Mediated Apoptosis in Zebrafish.	Zhu H, Wang Z, Wang W, Lu Y, He YW, Tian J.	Int J Mol Sci	10.3390/ijms23137110	2022
	The fliR gene contributes to the virulence of S. marcescens in a Drosophila intestinal infection model.	Sina Rahme B, Lestradet M, Di Venanzio G, Ayyaz A, Yamba MW, Lazzaro M, Liegeois S, Garcia Vescovi E, Ferrandon D.	Sci Rep	10.1038/s41598-022-06780-w	2022
Metabolism	Induction of cell wall thickening by the antifungal compound dihydromaltophilin disrupts fungal growth and is mediated by sphingolipid biosynthesis.	Li S, Calvo AM, Yuen GY, Du L, Harris SD.	J Eukaryot Microbiol	10.1111/j.1550-7408.2008.00384.x	2009
	Isolation and Characterization of NpCI, a New Metallocarboxypeptidase Inhibitor from the Marine Snail Nerita peloronta with Anti-Plasmodium falciparum Activity.	Cabrera-Munoz A, Sierra-Gomez Y, Covaleda-Cortes G, Reytor ML, Gonzalez-Gonzalez Y, Bautista JM, Aviles FX, Alonso-Del-Rivero M.	Mar Drugs	10.3390/md21020094	2023
Transcriptome	The Perception of Rhizosphere Bacterial Communication Signals Leads to Transcriptome Reprogramming in Lysobacter capsici AZ78, a Plant Beneficial Bacterium.	Bejarano A, Perazzolli M, Pertot I, Puopolo G.	Front Microbiol	10.3389/fmicb.2021.725403	2021
	Circulating SOD2 Is a Candidate Response Biomarker for Neoadjuvant Therapy in Breast Cancer.	Juliachs M, Pujals M, Bellio C, Meo-Evoli N, Duran JM, Zamora E, Pares M, Sunol A, Mendez O, Sanchez-Pla A, Canals F, Saura C, Villanueva J.	Cancers (Basel)	10.3390/cancers14163858	2022
	Biocontrol activity and action mechanism of Paenibacillus polymyxa strain Nl4 against pear Valsa canker caused by Valsa pyri.	Yuan H, Yuan M, Shi B, Wang Z, Huang T, Qin G, Hou H, Wang L, Tu H.	Front Microbiol	10.3389/fmicb.2022.950742	2022
	Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle.	Masania J, Wijten P, Keipert S, Ost M, Klaus S, Rabbani N, Thornalley PJ.	Redox Biol	10.1016/j.redox.2022.102574	2023
	Mutagenesis of beta-1,3-Glucanase Genes in Lysobacter enzymogenes Strain C3 Results in Reduced Biological Control Activity Toward Bipolaris Leaf Spot of Tall Fescue and Pythium Damping-Off of Sugar Beet.	Palumbo JD, Yuen GY, Jochum CC, Tatum K, Kobayashi DY.	Phytopathology	10.1094/phyto-95-0701	2005
	Secretory molecules from secretion systems fine-tune the host-beneficial bacteria (PGPRs) interaction.	Gupta G, Chauhan PS, Jha PN, Verma RK, Singh S, Yadav VK, Sahoo DK, Patel A.	Front Microbiol	10.3389/fmicb.2024.1355750	2024
	LC_Glucose-Inhibited Division Protein Is Required for Motility, Biofilm Formation, and Stress Response in Lysobacter capsici X2-3.	Zhao D, Wang H, Li Z, Han S, Han C, Liu A.	Front Microbiol	10.3389/fmicb.2022.840792	2022
	Biological Control of Oomycete Soilborne Diseases Caused by Phytophthora capsici, Phytophthora infestans, and Phytophthora nicotianae in Solanaceous Crops.	Volynchikova E, Kim KD.	Mycobiology	10.1080/12298093.2022.2136333	2022
Metabolism	Signaling specificity in the c-di-GMP-dependent network regulating antibiotic synthesis in Lysobacter.	Xu G, Han S, Huo C, Chin KH, Chou SH, Gomelsky M, Qian G, Liu F.	Nucleic Acids Res	10.1093/nar/gky803	2018
	Production of antifungal compounds by Lysobacter enzymogenes isolate 3.1T8 under different conditions in relation to its efficacy as a biocontrol agent of Pythium aphanidermatum in cucumber.	Folman LB, Klein MJEMde, Postma J, Veen JAvan.	Biol Control	10.1016/j.biocontrol.2004.03.008	2004
Metabolism	Transcriptomics Analysis of the Chinese Pear Pathotype of Alternaria alternata Gives Insights into Novel Mechanisms of HSAF Antifungal Activities.	He F, Li B, Ai G, Kange AM, Zhao Y, Zhang X, Jia Y, Dou D, Liu F, Cao H.	Int J Mol Sci	10.3390/ijms19071841	2018
	Comparison of strains of Lysobacter enzymogenes and PGPR for induction of resistance against Bipolaris sorokiniana in tall fescue	Kilic-Ekici O, Yuen GY.	Biol Control	10.1016/j.biocontrol.2004.01.014	2004
	Characterization of Collagen from Sakhalin Taimen Skin as Useful Biomass.	Nagai T, Saito M, Tanoue Y, Kai N, Suzuki N.	Food Technol Biotechnol	10.17113/ftb.58.04.20.6734	2020
	Effects of continuous cropping of sweet potatoes on the bacterial community structure in rhizospheric soil.	Gao Z, Hu Y, Han M, Xu J, Wang X, Liu L, Tang Z, Jiao W, Jin R, Liu M, Guan Z, Ma Z.	BMC Microbiol	10.1186/s12866-021-02120-6	2021
Genetics	Isolation, identification, and biochemical characterization of a novel bifunctional phosphomannomutase/phosphoglucomutase from the metagenome of the brown alga Laminaria digitata.	Jackson SA, Duan M, Zhang P, Ihua MW, Stengel DB, Duan D, Dobson ADW.	Front Microbiol	10.3389/fmicb.2022.1000634	2022
	Bactericidal effectors of the Stenotrophomonas maltophilia type IV secretion system: functional definition of the nuclease TfdA and structural determination of TfcB.	Cobe BL, Dey S, Minasov G, Inniss N, Satchell KJF, Cianciotto NP.	mBio	10.1128/mbio.01198-24	2024
	Diversity and Activity of Lysobacter Species from Disease Suppressive Soils.	Gomez Exposito R, Postma J, Raaijmakers JM, De Bruijn I.	Front Microbiol	10.3389/fmicb.2015.01243	2015
Metabolism	Biosynthesis of HSAF, a tetramic acid-containing macrolactam from Lysobacter enzymogenes.	Lou L, Qian G, Xie Y, Hang J, Chen H, Zaleta-Rivera K, Li Y, Shen Y, Dussault PH, Liu F, Du L.	J Am Chem Soc	10.1021/ja105732c	2011
	Characterisation of Lysobacter enzymogenes (Christensen and Cook 1978) strain 3.1T8, a powerful antagonist of fungal diseases of cucumber.	Folman LB, Postma J, van Veen JA.	Microbiol Res	10.1078/0944-5013-00185	2003
Pathogenicity	Allelic variations in the chpG effector gene within Clavibacter michiganensis populations determine pathogen host range.	Verma RK, Roman-Reyna V, Raanan H, Coaker G, Jacobs JM, Teper D.	PLoS Pathog	10.1371/journal.ppat.1012380	2024
Metabolism	Lysobacter PilR, the Regulator of Type IV Pilus Synthesis, Controls Antifungal Antibiotic Production via a Cyclic di-GMP Pathway.	Chen Y, Xia J, Su Z, Xu G, Gomelsky M, Qian G, Liu F.	Appl Environ Microbiol	10.1128/aem.03397-16	2017
Genetics	Microbiome and metagenomic analysis of Lake Hillier Australia reveals pigment-rich polyextremophiles and wide-ranging metabolic adaptations.	Sierra MA, Ryon KA, Tierney BT, Foox J, Bhattacharya C, Afshin E, Butler D, Green SJ, Thomas WK, Ramsdell J, Bivens NJ, McGrath K, Mason CE, Tighe SW.	Environ Microbiome	10.1186/s40793-022-00455-9	2022
	Synovial Fluid in Knee Osteoarthritis Extends Proinflammatory Niche for Macrophage Polarization.	Kulkarni P, Srivastava V, Tootsi K, Electricwala A, Kharat A, Bhonde R, Koks S, Martson A, Harsulkar A.	Cells	10.3390/cells11244115	2022
	Discovery of novel small molecule modulators of Clavibacter michiganensis subsp. michiganensis.	Xu X, Kumar A, Deblais L, Pina-Mimbela R, Nislow C, Fuchs JR, Miller SA, Rajashekara G.	Front Microbiol	10.3389/fmicb.2015.01127	2015
Phylogeny	Taxonomic positioning of two biological control agents for plant diseases as Lysobacter enzymogenes based on phylogenetic analysis of 16S rDNA, fatty acid composition and phenotypic characteristics.	Sullivan RF, Holtman MA, Zylstra GJ, White JF, Kobayashi DY.	J Appl Microbiol	10.1046/j.1365-2672.2003.01932.x	2003
	Ice nucleation in a Gram-positive bacterium isolated from precipitation depends on a polyketide synthase and non-ribosomal peptide synthetase.	Failor KC, Liu H, Llontop MEM, LeBlanc S, Eckshtain-Levi N, Sharma P, Reed A, Yang S, Tian L, Lefevre CT, Menguy N, Du L, Monteil CL, Vinatzer BA.	ISME J	10.1038/s41396-021-01140-4	2022
Pathogenicity	Fusarium Head Blight on Wheat: Biology, Modern Detection and Diagnosis and Integrated Disease Management.	Alisaac E, Mahlein AK.	Toxins (Basel)	10.3390/toxins15030192	2023
	The AHL Quorum-Sensing System Negatively Regulates Growth and Autolysis in Lysobacter brunescens.	Ling J, Zhou L, Wu G, Zhao Y, Jiang T, Liu F.	Front Microbiol	10.3389/fmicb.2019.02748	2019
	Crystal Structure of Inhibitor-Bound Bacterial Oligopeptidase B in the Closed State: Similarity and Difference between Protozoan and Bacterial Enzymes.	Petrenko DE, Karlinsky DM, Gordeeva VD, Arapidi GP, Britikova EV, Britikov VV, Nikolaeva AY, Boyko KM, Timofeev VI, Kuranova IP, Mikhailova AG, Bocharov EV, Rakitina TV.	Int J Mol Sci	10.3390/ijms24032286	2023
Enzymology	Structural investigations and identification of the extracellular bacteriolytic endopeptidase L1 from Lysobacter sp. XL1.	Muranova TA, Krasovskaya LA, Tsfasman IM, Stepnaya OA, Kulaev IS.	Biochemistry (Mosc)	10.1023/b:biry.0000029847.40511.26	2004
	Influence of Lysobacter enzymogenes Strain C3 on Nematodes.	Chen J, Moore WH, Yuen GY, Kobayashi D, Caswell-Chen EP.	J Nematol		2006
Transcriptome	Transcriptomics of the rice blast fungus Magnaporthe oryzae in response to the bacterial antagonist Lysobacter enzymogenes reveals candidate fungal defense response genes.	Mathioni SM, Patel N, Riddick B, Sweigard JA, Czymmek KJ, Caplan JL, Kunjeti SG, Kunjeti S, Raman V, Hillman BI, Kobayashi DY, Donofrio NM.	PLoS One	10.1371/journal.pone.0076487	2013
Enzymology	Exploring the microbiota dynamics related to vegetable biomasses degradation and study of lignocellulose-degrading bacteria for industrial biotechnological application.	Ventorino V, Aliberti A, Faraco V, Robertiello A, Giacobbe S, Ercolini D, Amore A, Fagnano M, Pepe O.	Sci Rep	10.1038/srep08161	2015
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Pathogenicity	Alteramide B is a microtubule antagonist of inhibiting Candida albicans.	Ding Y, Li Y, Li Z, Zhang J, Lu C, Wang H, Shen Y, Du L.	Biochim Biophys Acta	10.1016/j.bbagen.2016.06.025	2016
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Enzymology	Lysobacter strain with high lysyl endopeptidase production.	Chohnan S, Nonaka J, Teramoto K, Taniguchi K, Kameda Y, Tamura H, Kurusu Y, Norioka S, Masaki T, Sakiyama F.	FEMS Microbiol Lett	10.1111/j.1574-6968.2002.tb11279.x	2002
Metabolism	Mast Cells Differentiated in Synovial Fluid and Resident in Osteophytes Exalt the Inflammatory Pathology of Osteoarthritis.	Kulkarni P, Harsulkar A, Martson AG, Suutre S, Martson A, Koks S.	Int J Mol Sci	10.3390/ijms23010541	2022
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Metabolism	Identification and characterization of the anti-methicillin-resistant Staphylococcus aureus WAP-8294A2 biosynthetic gene cluster from Lysobacter enzymogenes OH11.	Zhang W, Li Y, Qian G, Wang Y, Chen H, Li YZ, Liu F, Shen Y, Du L.	Antimicrob Agents Chemother	10.1128/aac.05370-11	2011
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	Recruitment of the rhizo-microbiome army: assembly determinants and engineering of the rhizosphere microbiome as a key to unlocking plant potential.	Park I, Seo YS, Mannaa M.	Front Microbiol	10.3389/fmicb.2023.1163832	2023
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Genetics	Genome-scale metabolic reconstruction and in silico analysis of the rice leaf blight pathogen, Xanthomonas oryzae.	Koduru L, Kim HY, Lakshmanan M, Mohanty B, Lee YQ, Lee CH, Lee DY.	Mol Plant Pathol	10.1111/mpp.12914	2020
Pathogenicity	5-Methylindole Potentiates Aminoglycoside Against Gram-Positive Bacteria Including Staphylococcus aureus Persisters Under Hypoionic Conditions.	Sun F, Bian M, Li Z, Lv B, Gao Y, Wang Y, Fu X.	Front Cell Infect Microbiol	10.3389/fcimb.2020.00084	2020
Metabolism	Characterization of N-Acylhomoserine Lactones Produced by Bacteria Isolated from Industrial Cooling Water Systems.	Okutsu N, Morohoshi T, Xie X, Kato N, Ikeda T.	Sensors (Basel)	10.3390/s16010044	2015
Enzymology	Two energetically disparate folding pathways of alpha-lytic protease share a single transition state.	Derman AI, Agard DA.	Nat Struct Biol	10.1038/75172	2000
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Metabolism	Biosynthetic mechanism for sunscreens of the biocontrol agent Lysobacter enzymogenes.	Wang Y, Qian G, Li Y, Wang Y, Wang Y, Wright S, Li Y, Shen Y, Liu F, Du L.	PLoS One	10.1371/journal.pone.0066633	2013
	Synthesis of a 2,4,6,8,10-dodecapentanoic acid thioester as a substrate for biosynthesis of Heat Stable Antifungal Factor (HSAF).	Olson AS, Chen H, Du L, Dussault PH.	RSC Adv	10.1039/c4ra14829k	2015
Metabolism	Sensing of intracellular Hcp levels controls T6SS expression in Vibrio cholerae.	Manera K, Caro F, Li H, Pei TT, Hersch SJ, Mekalanos JJ, Dong TG.	Proc Natl Acad Sci U S A	10.1073/pnas.2104813118	2021
Pathogenicity	Critical Assessment of Streptomyces spp. Able to Control Toxigenic Fusaria in Cereals: A Literature and Patent Review.	Colombo EM, Kunova A, Cortesi P, Saracchi M, Pasquali M.	Int J Mol Sci	10.3390/ijms20246119	2019
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Enzymology	beta-Lactamase of Lysobacter enzymogenes: cloning, characterization and expression of the gene and comparison of the enzyme to other lactamases.	Boras GJ, Au S, Roy KL, von Tigerstrom RG.	J Gen Microbiol	10.1099/00221287-139-6-1245	1993
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Genetics	Streptomyces spp. From the Marine Sponge Antho dichotoma: Analyses of Secondary Metabolite Biosynthesis Gene Clusters and Some of Their Products.	Guerrero-Garzon JF, Zehl M, Schneider O, Ruckert C, Busche T, Kalinowski J, Bredholt H, Zotchev SB.	Front Microbiol	10.3389/fmicb.2020.00437	2020
Phylogeny	Structural comparison strengthens the higher-order classification of proteases related to chymotrypsin.	Monttinen HAM, Ravantti JJ, Poranen MM.	PLoS One	10.1371/journal.pone.0216659	2019
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Metabolism	AmpI Functions as an Iron Exporter To Alleviate beta-Lactam-Mediated Reactive Oxygen Species Stress in Stenotrophomonas maltophilia.	Huang YW, Huang HH, Huang KH, Chen WC, Lin YT, Hsu CC, Yang TC.	Antimicrob Agents Chemother	10.1128/aac.02467-18	2019
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Enzymology	The alpha-lytic protease gene of Lysobacter enzymogenes. The nucleotide sequence predicts a large prepro-peptide with homology to pro-peptides of other chymotrypsin-like enzymes.	Epstein DM, Wensink PC.	J Biol Chem	10.1016/s0021-9258(18)37430-1	1988
Metabolism	Phosphate-starvation induced changes in Thiobacillus ferrooxidans.	Seeger M, Jerez CA.	FEMS Microbiol Lett	10.1111/j.1574-6968.1993.tb06070.x	1993
Enzymology	Protease evolution in Streptomyces griseus. Discovery of a novel dimeric enzymes.	Sidhu SS, Kalmar GB, Willis LG, Borgford TJ.	J Biol Chem	10.1074/jbc.270.13.7594	1995
Enzymology	Streptomyces griseus protease C. A novel enzyme of the chymotrypsin superfamily.	Sidhu SS, Kalmar GB, Willis LG, Borgford TJ.	J Biol Chem	10.1016/s0021-9258(17)32141-5	1994
Enzymology	Characterization of the gene encoding the glutamic-acid-specific protease of Streptomyces griseus.	Sidhu SS, Kalmar GB, Borgford TJ.	Biochem Cell Biol	10.1139/o93-067	1993
Metabolism	Common biosynthetic origins for polycyclic tetramate macrolactams from phylogenetically diverse bacteria.	Blodgett JA, Oh DC, Cao S, Currie CR, Kolter R, Clardy J.	Proc Natl Acad Sci U S A	10.1073/pnas.1001513107	2010
Enzymology	A clp gene homologue belonging to the Crp gene family globally regulates lytic enzyme production, antimicrobial activity, and biological control activity expressed by Lysobacter enzymogenes strain C3.	Kobayashi DY, Reedy RM, Palumbo JD, Zhou JM, Yuen GY.	Appl Environ Microbiol	10.1128/aem.71.1.261-269.2005	2005
Enzymology	The use of Tween 20 in a sensitive turbidimetric assay of lipolytic enzymes.	von Tigerstrom RG, Stelmaschuk S.	Can J Microbiol	10.1139/m89-079	1989
Metabolism	Photolabeling a Nicotinic Acetylcholine Receptor (nAChR) with an (alpha4)3(beta2)2 nAChR-Selective Positive Allosteric Modulator.	Hamouda AK, Deba F, Wang ZJ, Cohen JB.	Mol Pharmacol	10.1124/mol.116.103341	2016
Metabolism	Mapping of an internal protease cleavage site in the Ssy5p component of the amino acid sensor of Saccharomyces cerevisiae and functional characterization of the resulting pro- and protease domains by gain-of-function genetics.	Poulsen P, Lo Leggio L, Kielland-Brandt MC.	Eukaryot Cell	10.1128/ec.5.3.601-608.2006	2006
Enzymology	Purification and characterization of a novel zinc-proteinase from cultures of Aeromonas hydrophila.	Loewy AG, Santer UV, Wieczorek M, Blodgett JK, Jones SW, Cheronis JC.	J Biol Chem	10.1016/s0021-9258(18)52979-3	1993
Enzymology	Use of endoproteinase Lys-C from Lysobacter enzymogenes in protein sequence analysis.	Jekel PA, Weijer WJ, Beintema JJ.	Anal Biochem	10.1016/0003-2697(83)90308-1	1983
Genetics	Diverse Cone-Snail Species Harbor Closely Related Streptomyces Species with Conserved Chemical and Genetic Profiles, Including Polycyclic Tetramic Acid Macrolactams.	Quezada M, Licona-Cassani C, Cruz-Morales P, Salim AA, Marcellin E, Capon RJ, Barona-Gomez F.	Front Microbiol	10.3389/fmicb.2017.02305	2017
	The complete amino acid sequence of the major Kunitz trypsin inhibitor from the seeds of Prosopsis juliflora.	Negreiros AN, Carvalho MM, Xavier Filho J, Blanco-Labra A, Shewry PR, Richardson M.	Phytochemistry	10.1016/s0031-9422(00)98207-4	1991
Metabolism	Characterization of Rarobacter faecitabidus protease I, a yeast-lytic serine protease having mannose-binding activity.	Shimoi H, Tadenuma M.	J Biochem	10.1093/oxfordjournals.jbchem.a123628	1991
Pathogenicity	Indole Reverses Intrinsic Antibiotic Resistance by Activating a Novel Dual-Function Importer.	Wang Y, Tian T, Zhang J, Jin X, Yue H, Zhang XH, Du L, Bai F.	mBio	10.1128/mbio.00676-19	2019
Enzymology	Identification of bacteria on the surface of clinically infected and non-infected prosthetic hip joints removed during revision arthroplasties by 16S rRNA gene sequencing and by microbiological culture.	Dempsey KE, Riggio MP, Lennon A, Hannah VE, Ramage G, Allan D, Bagg J.	Arthritis Res Ther	10.1186/ar2201	2007
Metabolism	Mining of unexplored habitats for novel chitinases--chiA as a helper gene proxy in metagenomics.	Cretoiu MS, Kielak AM, Abu Al-Soud W, Abu Al-Soud W, Sorensen SJ, van Elsas JD.	Appl Microbiol Biotechnol	10.1007/s00253-012-4057-5	2012
	Quantitative proteomics using ultralow flow capillary electrophoresis-mass spectrometry.	Faserl K, Kremser L, Muller M, Teis D, Lindner HH.	Anal Chem	10.1021/acs.analchem.5b00312	2015
	The alpha-lytic protease pro-region does not require a physical linkage to activate the protease domain in vivo.	Silen JL, Agard DA.	Nature	10.1038/341462a0	1989
Metabolism	An immunologically related family of apolipoproteins associated with triacylglycerol storage in the Cruciferae.	Au DM, Kang AS, Murphy DJ.	Arch Biochem Biophys	10.1016/0003-9861(89)90511-0	1989
Metabolism	Structural analysis of specificity: alpha-lytic protease complexes with analogues of reaction intermediates.	Bone R, Frank D, Kettner CA, Agard DA.	Biochemistry	10.1021/bi00445a015	1989
	Molecular analysis of the gene encoding alpha-lytic protease: evidence for a preproenzyme.	Silen JL, McGrath CN, Smith KR, Agard DA.	Gene	10.1016/0378-1119(88)90434-9	1988
	Serine protease mechanism: structure of an inhibitory complex of alpha-lytic protease and a tightly bound peptide boronic acid.	Bone R, Shenvi AB, Kettner CA, Agard DA.	Biochemistry	10.1021/bi00398a012	1987
	A photoreactive analog of allopregnanolone enables identification of steroid-binding sites in a nicotinic acetylcholine receptor.	Yu Z, Chiara DC, Savechenkov PY, Bruzik KS, Cohen JB.	J Biol Chem	10.1074/jbc.ra118.007172	2019
Metabolism	Extracellular nucleases of Lysobacter enzymogenes: production of the enzymes and purification and characterization of an endonuclease.	von Tigerstrom RG.	Can J Microbiol	10.1139/m80-175	1980
Metabolism	Positive and Negative Allosteric Modulation of an alpha1beta3gamma2 gamma-Aminobutyric Acid Type A (GABAA) Receptor by Binding to a Site in the Transmembrane Domain at the gamma+-beta- Interface.	Jayakar SS, Zhou X, Savechenkov PY, Chiara DC, Desai R, Bruzik KS, Miller KW, Cohen JB.	J Biol Chem	10.1074/jbc.m115.672006	2015
Metabolism	N-terminus of the protein kinase CLK1 induces SR protein hyperphosphorylation.	Aubol BE, Plocinik RM, Keshwani MM, McGlone ML, Hagopian JC, Ghosh G, Fu XD, Adams JA.	Biochem J	10.1042/bj20140494	2014
Proteome	Crystal Structure of Human Leukocyte Cell-derived Chemotaxin 2 (LECT2) Reveals a Mechanistic Basis of Functional Evolution in a Mammalian Protein with an M23 Metalloendopeptidase Fold.	Zheng H, Miyakawa T, Sawano Y, Asano A, Okumura A, Yamagoe S, Tanokura M.	J Biol Chem	10.1074/jbc.m116.720375	2016
Metabolism	BspK, a Serine Protease from the Predatory Bacterium Bdellovibrio bacteriovorus with Utility for Analysis of Therapeutic Antibodies.	Bratanis E, Molina H, Naegeli A, Collin M, Lood R.	Appl Environ Microbiol	10.1128/aem.03037-16	2017
	Refined structure of alpha-lytic protease at 1.7 A resolution. Analysis of hydrogen bonding and solvent structure.	Fujinaga M, Delbaere LT, Brayer GD, James MN.	J Mol Biol	10.1016/0022-2836(85)90296-7	1985
	Indigenous populations of three closely related Lysobacter spp. in agricultural soils using real-time PCR.	Postma J, Schilder MT, van Hoof RA.	Microb Ecol	10.1007/s00248-011-9847-2	2011
	Twitching and Swimming Motility Play a Role in Ralstonia solanacearum Pathogenicity.	Corral J, Sebastia P, Coll NS, Barbe J, Aranda J, Valls M.	mSphere	10.1128/msphere.00740-19	2020
Enzymology	p-Hydroxybenzoate hydroxylase from Pseudomonas fluorescens. 1. Completion of the elucidation of the primary structure.	Hofsteenge J, Weijer WJ, Jekel PA, Beintema JJ.	Eur J Biochem	10.1111/j.1432-1033.1983.tb07433.x	1983
Metabolism	Genetic determinants of reutericyclin biosynthesis in Lactobacillus reuteri.	Lin XB, Lohans CT, Duar R, Zheng J, Vederas JC, Walter J, Ganzle M.	Appl Environ Microbiol	10.1128/aem.03691-14	2015
Enzymology	Structure of mouse submaxillary gland renin.	Misono KS, Chang JJ, Inagami T.	Clin Exp Hypertens A	10.3109/10641968309048833	1983
Metabolism	Identification and biosynthesis of a novel xanthomonadin-dialkylresorcinol-hybrid from Azoarcus sp. BH72.	Schoner TA, Fuchs SW, Reinhold-Hurek B, Bode HB.	PLoS One	10.1371/journal.pone.0090922	2014
	Preparation and characterization of salmon calcitonin-biotin conjugates.	Cetin M, Youn YS, Capan Y, Lee KC.	AAPS PharmSciTech	10.1208/s12249-008-9165-2	2008
Metabolism	Wheat microbiome bacteria can reduce virulence of a plant pathogenic fungus by altering histone acetylation.	Chen Y, Wang J, Yang N, Wen Z, Sun X, Chai Y, Ma Z.	Nat Commun	10.1038/s41467-018-05683-7	2018
Enzymology	The amino acid sequence of the trimethoprim-resistant dihydrofolate reductase specified in Escherichia coli by R-plasmid R67.	Stone D, Smith SL.	J Biol Chem	10.1016/s0021-9258(19)86600-0	1979
Genetics	Underexplored bacteria as reservoirs of novel antimicrobial lipopeptides.	Clements-Decker T, Kode M, Khan S, Khan W.	Front Chem	10.3389/fchem.2022.1025979	2022
Metabolism	Tuning of pK_a values activates substrates in flavin-dependent aromatic hydroxylases.	Pitsawong W, Chenprakhon P, Dhammaraj T, Medhanavyn D, Sucharitakul J, Tongsook C, van Berkel WJH, Chaiyen P, Miller AF.	J Biol Chem	10.1074/jbc.ra119.011884	2020
	Structural basis for pH-insensitive inhibition of immunoglobulin G recycling by an anti-neonatal Fc receptor antibody.	Kenniston JA, Taylor BM, Conley GP, Cosic J, Kopacz KJ, Lindberg AP, Comeau SR, Atkins K, Bullen J, TenHoor C, Adelman BA, Sexton DJ, Sexton DJ, Edwards TE, Nixon AE.	J Biol Chem	10.1074/jbc.m117.807396	2017
Enzymology	Cloning and expression analysis of genes encoding lytic endopeptidases L1 and L5 from Lysobacter sp. strain XL1.	Lapteva YS, Zolova OE, Shlyapnikov MG, Tsfasman IM, Muranova TA, Stepnaya OA, Kulaev IS, Granovsky IE.	Appl Environ Microbiol	10.1128/aem.01621-12	2012
Metabolism	Identifying barbiturate binding sites in a nicotinic acetylcholine receptor with [3H]allyl m-trifluoromethyldiazirine mephobarbital, a photoreactive barbiturate.	Hamouda AK, Stewart DS, Chiara DC, Savechenkov PY, Bruzik KS, Cohen JB.	Mol Pharmacol	10.1124/mol.113.090985	2014
Metabolism	The PilB-PilZ-FimX regulatory complex of the Type IV pilus from Xanthomonas citri.	Llontop EE, Cenens W, Favaro DC, Sgro GG, Salinas RK, Guzzo CR, Farah CS.	PLoS Pathog	10.1371/journal.ppat.1009808	2021
Phylogeny	Biocontrol and plant growth-promoting activity of rhizobacteria from Chinese fields with contaminated soils.	Wang X, Mavrodi DV, Ke L, Mavrodi OV, Yang M, Thomashow LS, Zheng N, Weller DM, Zhang J.	Microb Biotechnol	10.1111/1751-7915.12158	2015
Enzymology	Cryptic polyketide synthase genes in non-pathogenic Clostridium SPP.	Behnken S, Hertweck C.	PLoS One	10.1371/journal.pone.0029609	2012
Pathogenicity	Fungal Innate Immunity Induced by Bacterial Microbe-Associated Molecular Patterns (MAMPs).	Ipcho S, Sundelin T, Erbs G, Kistler HC, Newman MA, Olsson S.	G3 (Bethesda)	10.1534/g3.116.027987	2016
Enzymology	The Lysobacter capsici AZ78 Genome Has a Gene Pool Enabling it to Interact Successfully with Phytopathogenic Microorganisms and Environmental Factors.	Puopolo G, Tomada S, Sonego P, Moretto M, Engelen K, Perazzolli M, Pertot I.	Front Microbiol	10.3389/fmicb.2016.00096	2016
Proteome	Cysteine sulfenic acid as an intermediate in disulfide bond formation and nonenzymatic protein folding.	Rehder DS, Borges CR.	Biochemistry	10.1021/bi1008694	2010
	Scavenger Receptor A Mediates the Clearance and Immunological Screening of MDA-Modified Antigen by M2-Type Macrophages.	Warnecke A, Abele S, Musunuri S, Bergquist J, Harris RA.	Neuromolecular Med	10.1007/s12017-017-8461-y	2017
	Modeling and structural analysis of PA clan serine proteases.	Laskar A, Rodger EJ, Chatterjee A, Mandal C.	BMC Res Notes	10.1186/1756-0500-5-256	2012
Metabolism	Mapping general anesthetic binding site(s) in human alpha1beta3 gamma-aminobutyric acid type A receptors with [³H]TDBzl-etomidate, a photoreactive etomidate analogue.	Chiara DC, Dostalova Z, Jayakar SS, Zhou X, Miller KW, Cohen JB.	Biochemistry	10.1021/bi201772m	2012
Metabolism	The multifactorial basis for plant health promotion by plant-associated bacteria.	Kim YC, Leveau J, McSpadden Gardener BB, Pierson EA, Pierson LS, Ryu CM.	Appl Environ Microbiol	10.1128/aem.01867-10	2011
Metabolism	Tau interactome analyses in CRISPR-Cas9 engineered neuronal cells reveal ATPase-dependent binding of wild-type but not P301L Tau to non-muscle myosins.	Wang X, Williams D, Muller I, Lemieux M, Dukart R, Maia IBL, Wang H, Woerman AL, Schmitt-Ulms G.	Sci Rep	10.1038/s41598-019-52543-5	2019
Phylogeny	Phylogenetic and multivariate analyses to determine the effects of different tillage and residue management practices on soil bacterial communities.	Ceja-Navarro JA, Rivera-Orduna FN, Patino-Zuniga L, Vila-Sanjurjo A, Crossa J, Govaerts B, Dendooven L.	Appl Environ Microbiol	10.1128/aem.02726-09	2010
Metabolism	MRG15-mediated tethering of PALB2 to unperturbed chromatin protects active genes from genotoxic stress.	Bleuyard JY, Fournier M, Nakato R, Couturier AM, Katou Y, Ralf C, Hester SS, Dominguez D, Rhodes D, Humphrey TC, Shirahige K, Esashi F.	Proc Natl Acad Sci U S A	10.1073/pnas.1620208114	2017
	Splicing kinase SRPK1 conforms to the landscape of its SR protein substrate.	Aubol BE, Jamros MA, McGlone ML, Adams JA.	Biochemistry	10.1021/bi4010864	2013
	Revisiting the Cellulosimicrobium cellulans yeast-lytic beta-1,3-glucanases toolbox: a review.	Ferrer P.	Microb Cell Fact	10.1186/1475-2859-5-10	2006
Genetics	Comparative genome analysis reveals an absence of leucine-rich repeat pattern-recognition receptor proteins in the kingdom Fungi.	Soanes DM, Talbot NJ.	PLoS One	10.1371/journal.pone.0012725	2010
	Enantiomeric barbiturates bind distinct inter- and intrasubunit binding sites in a nicotinic acetylcholine receptor (nAChR).	Yu Z, Cohen JB.	J Biol Chem	10.1074/jbc.m117.808592	2017
	Desformylflustrabromine (dFBr) and [3H]dFBr-Labeled Binding Sites in a Nicotinic Acetylcholine Receptor.	Hamouda AK, Wang ZJ, Stewart DS, Jain AD, Glennon RA, Cohen JB.	Mol Pharmacol	10.1124/mol.115.098913	2015
	Broad Spectrum Antimicrobial Activity of Forest-Derived Soil Actinomycete, Nocardia sp. PB-52.	Sharma P, Kalita MC, Thakur D.	Front Microbiol	10.3389/fmicb.2016.00347	2016
Metabolism	Cyclin-dependent kinase 5 regulates PSD-95 ubiquitination in neurons.	Bianchetta MJ, Lam TT, Jones SN, Morabito MA.	J Neurosci	10.1523/jneurosci.2388-11.2011	2011
Metabolism	Control of glucosylceramide production and morphogenesis by the Bar1 ceramide synthase in Fusarium graminearum.	Rittenour WR, Chen M, Cahoon EB, Harris SD.	PLoS One	10.1371/journal.pone.0019385	2011
Metabolism	Characterization of an endoprotease (PrpL) encoded by a PvdS-regulated gene in Pseudomonas aeruginosa.	Wilderman PJ, Vasil AI, Johnson Z, Wilson MJ, Cunliffe HE, Lamont IL, Vasil ML.	Infect Immun	10.1128/iai.69.9.5385-5394.2001	2001
Metabolism	Catalytic mechanism of serine proteases: reexamination of the pH dependence of the histidyl 1J13C2-H coupling constant in the catalytic triad of alpha-lytic protease.	Bachovchin WW, Kaiser R, Richards JH, Roberts JD.	Proc Natl Acad Sci U S A	10.1073/pnas.78.12.7323	1981
	Molecular cloning and nucleotide sequence of the beta-lytic protease gene from Achromobacter lyticus.	Li SL, Norioka S, Sakiyama F.	J Bacteriol	10.1128/jb.172.11.6506-6511.1990	1990
Metabolism	Hydrolase and glycosynthase activity of endo-1,3-beta-glucanase from the thermophile Pyrococcus furiosus.	van Lieshout J, Faijes M, Nieto J, van der Oost J, Planas A.	Archaea	10.1155/2004/731548	2004
Metabolism	Physostigmine and galanthamine bind in the presence of agonist at the canonical and noncanonical subunit interfaces of a nicotinic acetylcholine receptor.	Hamouda AK, Kimm T, Cohen JB.	J Neurosci	10.1523/jneurosci.3483-12.2013	2013
	Quantification of cysteine oxidation in human estrogen receptor by mass spectrometry.	Atsriku C, Benz CC, Scott GK, Gibson BW, Baldwin MA.	Anal Chem	10.1021/ac062154o	2007
Metabolism	Regulating SR protein phosphorylation through regions outside the kinase domain of SRPK1.	Plocinik RM, Li S, Liu T, Hailey KL, Whitesides J, Ma CT, Fu XD, Gosh G, Woods VL, Jennings PA, Adams JA.	J Mol Biol	10.1016/j.jmb.2011.04.077	2011
Metabolism	Multiple propofol-binding sites in a gamma-aminobutyric acid type A receptor (GABAAR) identified using a photoreactive propofol analog.	Jayakar SS, Zhou X, Chiara DC, Dostalova Z, Savechenkov PY, Bruzik KS, Dailey WP, Miller KW, Eckenhoff RG, Cohen JB.	J Biol Chem	10.1074/jbc.m114.581728	2014
Metabolism	[(3)H]chlorpromazine photolabeling of the torpedo nicotinic acetylcholine receptor identifies two state-dependent binding sites in the ion channel.	Chiara DC, Hamouda AK, Ziebell MR, Mejia LA, Garcia G, Cohen JB.	Biochemistry	10.1021/bi901271w	2009
Metabolism	Correct folding of alpha-lytic protease is required for its extracellular secretion from Escherichia coli.	Fujishige A, Smith KR, Silen JL, Agard DA.	J Cell Biol	10.1083/jcb.118.1.33	1992
Metabolism	Proteinase K-resistant material in ARR/VRQ sheep brain affected with classical scrapie is composed mainly of VRQ prion protein.	Jacobs JG, Bossers A, Rezaei H, van Keulen LJ, McCutcheon S, Sklaviadis T, Lantier I, Berthon P, Lantier F, van Zijderveld FG, Langeveld JP.	J Virol	10.1128/jvi.00448-11	2011
Enzymology	Evolution of the regulatory isozymes of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase present in the Escherichia coli genealogy.	Ahmad S, Rightmire B, Jensen RA.	J Bacteriol	10.1128/jb.165.1.146-154.1986	1986
	Identification of propofol binding sites in a nicotinic acetylcholine receptor with a photoreactive propofol analog.	Jayakar SS, Dailey WP, Eckenhoff RG, Cohen JB.	J Biol Chem	10.1074/jbc.m112.435909	2013
	alpha-lytic protease can exist in two separately stable conformations with different His57 mobilities and catalytic activities.	Haddad KC, Sudmeier JL, Bachovchin DA, Bachovchin WW.	Proc Natl Acad Sci U S A	10.1073/pnas.0409279102	2005
	The unique biosynthetic route from lupinus beta-conglutin gene to blad.	Monteiro S, Freitas R, Rajasekhar BT, Teixeira AR, Ferreira RB.	PLoS One	10.1371/journal.pone.0008542	2010
	Specificity of intersubunit general anesthetic-binding sites in the transmembrane domain of the human alpha1beta3gamma2 gamma-aminobutyric acid type A (GABAA) receptor.	Chiara DC, Jayakar SS, Zhou X, Zhang X, Savechenkov PY, Bruzik KS, Miller KW, Cohen JB.	J Biol Chem	10.1074/jbc.m113.479725	2013
Enzymology	Analysis of prepro-alpha-lytic protease expression in Escherichia coli reveals that the pro region is required for activity.	Silen JL, Frank D, Fujishige A, Bone R, Agard DA.	J Bacteriol	10.1128/jb.171.3.1320-1325.1989	1989
	Insights into affinity and specificity in the complexes of alpha-lytic protease and its inhibitor proteins: binding free energy from molecular dynamics simulation.	Deng NJ, Cieplak P.	Phys Chem Chem Phys	10.1039/b820961h	2009
Metabolism	Functional analysis of the Burkholderia cenocepacia ZmpA metalloprotease.	Kooi C, Corbett CR, Sokol PA.	J Bacteriol	10.1128/jb.187.13.4421-4429.2005	2005
	Unusual sulfonolipids are characteristic of the Cytophaga-Flexibacter group.	Godchaux W, Leadbetter ER.	J Bacteriol	10.1128/jb.153.3.1238-1246.1983	1983
Metabolism	Amino-terminal protein fusions to the TraR quorum-sensing transcription factor enhance protein stability and autoinducer-independent activity.	Chai Y, Winans SC.	J Bacteriol	10.1128/jb.187.4.1219-1226.2005	2005
	Unusual 1H NMR chemical shifts support (His) C(epsilon) 1...O==C H-bond: proposal for reaction-driven ring flip mechanism in serine protease catalysis.	Ash EL, Sudmeier JL, Day RM, Vincent M, Torchilin EV, Haddad KC, Bradshaw EM, Sanford DG, Bachovchin WW.	Proc Natl Acad Sci U S A	10.1073/pnas.97.19.10371	2000
Metabolism	Biochemical and genetic characterization of coagulin, a new antilisterial bacteriocin in the pediocin family of bacteriocins, produced by Bacillus coagulans I(4).	Le Marrec C, Hyronimus B, Bressollier P, Verneuil B, Urdaci MC.	Appl Environ Microbiol	10.1128/aem.66.12.5213-5220.2000	2000
Metabolism	Mechanism of dephosphorylation of the SR protein ASF/SF2 by protein phosphatase 1.	Ma CT, Ghosh G, Fu XD, Adams JA.	J Mol Biol	10.1016/j.jmb.2010.08.024	2010
	Regiospecific phosphorylation control of the SR protein ASF/SF2 by SRPK1.	Ma CT, Hagopian JC, Ghosh G, Fu XD, Adams JA.	J Mol Biol	10.1016/j.jmb.2009.05.060	2009
Enzymology	Molecular modeling of family GH16 glycoside hydrolases: potential roles for xyloglucan transglucosylases/hydrolases in cell wall modification in the poaceae.	Strohmeier M, Hrmova M, Fischer M, Harvey AJ, Fincher GB, Pleiss J.	Protein Sci	10.1110/ps.04828404	2004
Metabolism	Adaptable molecular interactions guide phosphorylation of the SR protein ASF/SF2 by SRPK1.	Hagopian JC, Ma CT, Meade BR, Albuquerque CP, Ngo JC, Ghosh G, Jennings PA, Fu XD, Adams JA.	J Mol Biol	10.1016/j.jmb.2008.07.055	2008
	The Haemophilus influenzae HtrA protein is a protective antigen.	Loosmore SM, Yang YP, Oomen R, Shortreed JM, Coleman DC, Klein MH.	Infect Immun	10.1128/iai.66.3.899-906.1998	1998
Metabolism	Insights from bacterial subtilases into the mechanisms of intramolecular chaperone-mediated activation of furin.	Shinde U, Thomas G.	Methods Mol Biol	10.1007/978-1-61779-204-5_4	2011
Enzymology	Comparison of the phosphatases of Lysobacter enzymogenes with those of related bacteria.	von Tigerstrom RG, Stelmaschuk S	J Gen Microbiol	10.1099/00221287-133-11-3121	1987
Metabolism	Enhancing proteolytic activity of Lysobacter enzymogenes using cold atmospheric plasma.	Tabar FF, Valizadeh V, Keramati M, Davoudi M, Molasalehi S, Fakhabi NS, Atyabi SM, Cohan RA, Norouzian D	Arch Microbiol	10.1007/s00203-022-02936-4	2022
Genetics	Comparative genomics provides insights into the potential biocontrol mechanism of two Lysobacter enzymogenes strains with distinct antagonistic activities.	Xu S, Zhang Z, Xie X, Shi Y, Chai A, Fan T, Li B, Li L	Front Microbiol	10.3389/fmicb.2022.966986	2022
	Description of Luteimonas pelagia sp. nov., isolated from marine sediment, and emended descriptions of Luteimonas aquatica, Luteimonas composti, Luteimonas mephitis, Lysobacter enzymogenes and Lysobacter panaciterrae.	Lin SY, Hameed A, Shahina M, Liu YC, Hsu YH, Wen CZ, Young CC.	Int J Syst Evol Microbiol	10.1099/ijsem.0.000769	2016
Phylogeny	Reclassification of Pseudomonas sp. PB-6250T as Lysobacter firmicutimachus sp. nov.	Miess H, van Trappen S, Cleenwerck I, De Vos P, Gross H	Int J Syst Evol Microbiol	10.1099/ijsem.0.001329	2016
Phylogeny	Lysobacter terrestris sp. nov., isolated from soil.	Woo CY, Kim J	Int J Syst Evol Microbiol	10.1099/ijsem.0.005204	2022
Phylogeny	Lysobacter silvisoli sp. nov., isolated from forest soil.	Zhang XJ, Yao Q, Wang YH, Yang SZ, Feng GD, Zhu HH	Int J Syst Evol Microbiol	10.1099/ijsem.0.003105	2018
Phylogeny	Lysobacter cavernae sp. nov., a novel bacterium isolated from a cave sample.	Chen W, Zhao YL, Cheng J, Zhou XK, Salam N, Fang BZ, Li QQ, Hozzein WN, Li WJ	Antonie Van Leeuwenhoek	10.1007/s10482-016-0704-7	2016
Phylogeny	Lysobacter agri sp. nov., a bacterium isolated from soil.	Singh H, Won K, Du J, Yang JE, Akter S, Kim KY, Yi TH	Antonie Van Leeuwenhoek	10.1007/s10482-015-0510-7	2015
Phylogeny	Lysobacter korlensis sp. nov. and Lysobacter bugurensis sp. nov., isolated from soil.	Zhang L, Bai J, Wang Y, Wu GL, Dai J, Fang CX	Int J Syst Evol Microbiol	10.1099/ijs.0.024448-0	2010
Phylogeny	Lysobacter soli sp. nov., isolated from soil of a ginseng field.	Srinivasan S, Kim MK, Sathiyaraj G, Kim HB, Kim YJ, Yang DC	Int J Syst Evol Microbiol	10.1099/ijs.0.016428-0	2009
Phylogeny	'Lysobacter enzymogenes ssp. cookii ' Christensen 1978 should be recognized as an independent species, Lysobacter cookii sp. nov.	Kawamura Y, Tomida J, Morita Y, Naka T, Mizuno S, Fujiwara N	FEMS Microbiol Lett	10.1111/j.1574-6968.2009.01703.x	2009
Phylogeny	Lysobacter oryzae sp. nov., isolated from the rhizosphere of rice (Oryza sativa L.).	Aslam Z, Yasir M, Jeon CO, Chung YR	Int J Syst Evol Microbiol	10.1099/ijs.0.000588-0	2009
Phylogeny	Lysobacter niabensis sp. nov. and Lysobacter niastensis sp. nov., isolated from greenhouse soils in Korea.	Weon HY, Kim BY, Kim MK, Yoo SH, Kwon SW, Go SJ, Stackebrandt E	Int J Syst Evol Microbiol	10.1099/ijs.0.64473-0	2007
Phylogeny	Two novel species, Lysobacter daejeonensis sp. nov. and Lysobacter yangpyeongensis sp. nov., isolated from Korean greenhouse soils.	Weon HY, Kim BY, Baek YK, Yoo SH, Kwon SW, Stackebrandt E, Go SJ	Int J Syst Evol Microbiol	10.1099/ijs.0.64095-0	2006
Phylogeny	Lysobacter koreensis sp. nov., isolated from a ginseng field.	Lee JW, Im WT, Kim MK, Yang DC	Int J Syst Evol Microbiol	10.1099/ijs.0.63955-0	2006
Phylogeny	Lysobacter selenitireducens sp. nov., isolated from river sediment.	Mao S, Li S, Guo B, Mu W, Hou X, Liu H, Wei S, Liu A, Kong L, Chen Z	Int J Syst Evol Microbiol	10.1099/ijsem.0.005550	2022

References

#685	Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 2043
#20215	Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 )
#20216	Curators of the HKI: Collection Description Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie e. V. Hans-Knöll-Institut (HKI) . Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie e. V. Hans-Knöll-Institut (HKI):
#43356	R.F. Sullivan, M.A. Holtman, G.J. Zylstra, J.F. White Jr, D.Y. Kobayashi: Taxonomic positioning of two biological control agents for plant diseases as Lysobacter enzymogenes based on phylogenetic analysis of 16S rDNA, fatty acid composition and phenotypic characteristics. J. app. Microbiol. 94: 1079 - 1086 2003 ( DOI 10.1046/j.1365-2672.2003.01932 )
#45040	Culture Collection University of Gothenburg (CCUG) ; Curators of the CCUG; CCUG 7833
#66792	Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) .
#66794	Antje Chang, Lisa Jeske, Sandra Ulbrich, Julia Hofmann, Julia Koblitz, Ida Schomburg, Meina Neumann-Schaal, Dieter Jahn, Dietmar Schomburg: BRENDA, the ELIXIR core data resource in 2021: new developments and updates. Nucleic Acids Res. 49: D498 - D508 2020 ( DOI 10.1093/nar/gkaa1025 , PubMed 33211880 )
#67771	Korean Collection for Type Cultures (KCTC) ; Curators of the KCTC;
#68369	Automatically annotated from API 20NE .
#69479	João F Matias Rodrigues, Janko Tackmann,Gregor Rot, Thomas SB Schmidt, Lukas Malfertheiner, Mihai Danaila,Marija Dmitrijeva, Daniela Gaio, Nicolas Näpflin and Christian von Mering. University of Zurich.: MicrobeAtlas 1.0 beta .
#124043	Isabel Schober, Julia Koblitz: Data extracted from sequence databases, automatically matched based on designation and taxonomy .
#125438	Julia Koblitz, Lorenz Christian Reimer, Rüdiger Pukall, Jörg Overmann: Predicting bacterial phenotypic traits through improved machine learning using high-quality, curated datasets. 2024 ( DOI 10.1101/2024.08.12.607695 )
#125439	Philipp Münch, René Mreches, Martin Binder, Hüseyin Anil Gündüz, Xiao-Yin To, Alice McHardy: deepG: Deep Learning for Genome Sequence Data. R package version 0.3.1 .
#126262	A. Lissin, I. Schober, J. F. Witte, H. Lüken, A. Podstawka, J. Koblitz, B. Bunk, P. Dawyndt, P. Vandamme, P. de Vos, J. Overmann, L. C. Reimer: StrainInfo—the central database for linked microbial strain identifiers. ( DOI 10.1093/database/baaf059 )

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Lysobacter enzymogenes (DSM 2043, ATCC 29487, VKM B-2235)

Name and taxonomic classification

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Physiology and metabolism

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Genome browser: GCA_900106525

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