Name: Tannerella forsythia CCUG 21028 A
Creator: BacDive
License: https://creativecommons.org/licenses/by/4.0/

Strain identifier

BacDive ID: 143693

Type strain:

Species: Tannerella forsythia

Culture col. no.: CCUG 21028 A, ATCC 43037, CCUG 33064, JCM 10827, CCUG 33226, CIP 105219, KCTC 5666

Strain history: M. Umeda <-- ATCC 43037 <-- A. C. R. Tanner FDC 338.

NCBI tax ID(s): 28112 (species)

SI-ID 41611

ATCC 43037, CCUG 21028 A, CCUG 33226, CIP 105219, JCM 10827, CIP 106219, DSM 18712, CCUG 33064

Other strains from Tannerella forsythia

T. forsythia P1F20A, W10960, WW10960, DSM 102835
T. forsythia CIP 105220, FDC 42
T. forsythia CCUG 51269
T. forsythia CCUG 57306

Section

Tannerella forsythia CCUG 21028 A is an anaerobe, Gram-negative bacterium that was isolated from Human periodontal pocket.

Gram-negative
anaerobe
16S sequence
Bacteria
genome sequence

Information on the name and the taxonomic classification. Name and taxonomic classification

	Last LPSN update	14-12-2023 (DD-MM-YYYY)
	Domain	"Bacteria"
	Phylum	*Bacteroidota*
	Class	*Bacteroidia*
	Order	*Bacteroidales*
	Family	*Tannerellaceae*
	Genus	*Tannerella*
	Species	**Tannerella forsythia**
	Full Scientific Name (LPSN)	Tannerella forsythia corrig. (Tanner et al. 1986) Sakamoto et al. 2002

	Synonym	Tannerella forsythensis
	Synonym	Bacteroides forsythus

Information on morphological and physiological properties Morphology

[Ref.: #69480]	Gram stain	negative Confidence in %97.548

[Ref.: #69480]	Motility	no Confidence in %90.217

[Ref.: #47258]

Incubation period

7 days

Information on culture and growth conditions Culture and growth conditions

	Temperatures	Kind of temperature		Temperature
[Ref.: #47258]			growth	37 °C
[Ref.: #67770]			growth	37 °C

Information on physiology and metabolism Physiology and metabolism

[Ref.: #47258]	Oxygen tolerance	anaerobe
[Ref.: #69480]	Oxygen tolerance	anaerobe Confidence in %98.651

[Ref.: #69480]	Ability of spore formation	no Confidence in %94.398
[Ref.: #69481]	Ability of spore formation	no Confidence in %99

[Ref.: #67770]

Observation

quinones: MK-10, MK-11

Information on isolation source, the sampling and environmental conditions Isolation, sampling and environmental information

[Ref.: #47258]	Sample type/isolated from	Human periodontal pocket
[Ref.: #47258]	Geographic location (country and/or sea, region)	Massachusetts
[Ref.: #47258]	Country	USA
[Ref.: #47258]	Country ISO 3 Code	USA
[Ref.: #47258]	Continent	North America

[Ref.: #67770]	Sample type/isolated from	Periodontal pockets
* marker position based on {}

Isolation sources categories

#Host	#Human	-
#Host Body-Site	#Oral cavity and airways	#Periodontal pocket

What are isolation sources categories?

[Ref.: #69479]

Global distribution of 16S sequence AB547708 (>99% sequence identity) for Tannerella forsythia subclade from Microbeatlas

Aquatic Samples	902
Soil Samples	571
Animal Samples	72607
Plant Samples	260
Total Samples	74340

Information on genomic background e.g. entries in nucleic sequence databass Sequence information

16S Sequence information:

	Sequence accession description	Seq. accession number	Sequence length (bp)	Sequence database	Associated NCBI tax ID
[Ref.: #67770]	Tannerella forsythia gene for 16S ribosomal RNA, partial sequence, strain: JCM 10827	AB547708	1486	GenBank ENA	28112 tax ID
[Ref.: #67770]	Bacteroides forsythus 16S ribosomal RNA gene, complete sequence	L16495	1466	GenBank ENA	28112 tax ID
[Ref.: #67770]	Bacteroides forsythus gene for 16S rRNA, partial sequence, strain:ATCC43037	AB035460	1466	GenBank ENA	28112 tax ID
[Ref.: #124043]	Bacteroides forsythus strain ATCC 43037 16S-23S intergenic spacer region, complete sequence	AF466818	740	GenBank ENA	28112 tax ID	*

Genome sequence information:

Only first 5 entries are displayed. Click here to see all.

	Sequence accession description	Seq. accession number	Assembly level	Sequence database	Associated NCBI tax ID
[Ref.: #67770]	Tannerella forsythia ATCC 43037	GCA_006385365	scaffold	GenBank ENA	28112 tax ID
[Ref.: #66792]	Tannerella forsythia 3313	1307832.4	complete	PATRIC	1307832 tax ID	*
[Ref.: #66792]	Tannerella forsythia ATCC 43037	203275.8	complete	PATRIC	203275 tax ID	*
[Ref.: #66792]	Tannerella forsythia KS16	1307833.4	complete	PATRIC	1307833 tax ID	*
[Ref.: #66792]	Tannerella forsythia strain ATCC 43037	28112.57	wgs	PATRIC	28112 tax ID	*
[Ref.: #66792]	Tannerella forsythia strain ATCC 43037	28112.6	wgs	PATRIC	28112 tax ID	*

[Ref.: #67770]

GC-content

46 mol%

thermal denaturation, midpoint method (Tm)

Data predicted using genome information as a basis Genome-based predictions

	Trait	Prediction	Confidence in %	In training data
	Predictions from GenomeNet Sporulation v. 1 based on: Tannerella forsythia KS16 PATRIC: 1307833.4
[Ref.: #69481]	spore-forming	no	99	no

	Trait	Prediction	Confidence in %	In training data
	Predictions from Diaspora project based on: Tannerella forsythia 3313 PATRIC: 1307832.4
[Ref.: #69480]	motile	no	90.217	no
[Ref.: #69480]	gram-positive	no	97.548	no
[Ref.: #69480]	anaerobic	yes	98.651	yes
[Ref.: #69480]	halophile	no	85.9	no
[Ref.: #69480]	spore-forming	no	94.398	no
[Ref.: #69480]	thermophile	no	97.509	yes
[Ref.: #69480]	glucose-util	yes	86.454	no
[Ref.: #69480]	aerobic	no	97.747	yes
[Ref.: #69480]	flagellated	no	98.208	no
[Ref.: #69480]	glucose-ferment	no	51.584	no

Availability in culture collections External links

[Ref.: #47258]

Culture collection no.

CCUG 21028 A, ATCC 43037, CCUG 33064, JCM 10827, CCUG 33226, CIP 105219, KCTC 5666

[Ref.: #99022]

SI-ID 41611

Literature:

Only first 10 entries are displayed. Click here to see all.

	Title	Authors	Journal	DOI	Year
Pathogenicity	Presence of Specific Periodontal Pathogens in Prostate Gland Diagnosed With Chronic Inflammation and Adenocarcinoma.	Alluri LSC, Paes Batista da Silva A, Verma S, Fu P, Shen DL, MacLennan G, Gupta S, Bissada NF	Cureus	10.7759/cureus.17742	2021	*
Genetics	Tannerella forsythia strains display different cell-surface nonulosonic acids: biosynthetic pathway characterization and first insight into biological implications.	Friedrich V, Janesch B, Windwarder M, Maresch D, Braun ML, Megson ZA, Vinogradov E, Goneau MF, Sharma A, Altmann F, Messner P, Schoenhofen IC, Schaffer C	Glycobiology	10.1093/glycob/cww129	2017	*
Metabolism	Dentilisin involvement in coaggregation between Treponema denticola and Tannerella forsythia.	Sano Y, Okamoto-Shibayama K, Tanaka K, Ito R, Shintani S, Yakushiji M, Ishihara K	Anaerobe	10.1016/j.anaerobe.2014.08.008	2014	*
Pathogenicity	Mixture of periodontopathogenic bacteria influences interaction with KB cells.	Kirschbaum M, Schultze-Mosgau S, Pfister W, Eick S	Anaerobe	10.1016/j.anaerobe.2010.03.009	2010	*
Phylogeny	Reclassification of Bacteroides forsythus (Tanner et al. 1986) as Tannerella forsythensis corrig., gen. nov., comb. nov.	Sakamoto M, Suzuki M, Umeda M, Ishikawa I, Benno Y	Int J Syst Evol Microbiol	10.1099/00207713-52-3-841	2002	*
Enzymology	Molecular detection of Bacteroides forsythus in human periodontitis.	Lotufo RF, Flynn J, Chen C, Slots J	Oral Microbiol Immunol	10.1111/j.1399-302x.1994.tb00052.x	1994	*
Pathogenicity	Tannerella forsythia strains differentially induce interferon gamma-induced protein 10 (IP-10) expression in macrophages due to lipopolysaccharide heterogeneity.	Chinthamani S, Settem RP, Honma K, Stafford GP, Sharma A	Pathog Dis	10.1093/femspd/ftac008	2022	*
Phylogeny	Tannerella serpentiformis sp. nov., isolated from the human mouth.	Ansbro K, Wade WG, Stafford GP	Int J Syst Evol Microbiol	10.1099/ijsem.0.004229	2020	*
Phylogeny	Comparative genome characterization of the periodontal pathogen Tannerella forsythia.	Zwickl NF, Stralis-Pavese N, Schaffer C, Dohm JC, Himmelbauer H	BMC Genomics	10.1186/s12864-020-6535-y	2020	*
Metabolism	Immune response profiling of primary monocytes and oral keratinocytes to different Tannerella forsythia strains and their cell surface mutants.	Bloch S, Zwicker S, Bostanci N, Sjoling A, Bostrom EA, Belibasakis GN, Schaffer C	Mol Oral Microbiol	10.1111/omi.12208	2018	*
Pathogenicity	Energy dispersive spectroscopy-scanning transmission electron microscope observations of free radical production in human polymorphonuclear leukocytes phagocytosing non-opsonized Tannerella forsythia.	Moriguchi K, Hasegawa Y, Higuchi N, Murakami Y, Yoshimura F, Nakata K, Honda M	Microsc Res Tech	10.1002/jemt.22819	2017	*
Metabolism	A pseudaminic acid or a legionaminic acid derivative transferase is strain-specifically implicated in the general protein O-glycosylation system of the periodontal pathogen Tannerella forsythia.	Tomek MB, Janesch B, Maresch D, Windwarder M, Altmann F, Messner P, Schaffer C	Glycobiology	10.1093/glycob/cwx019	2017	*
Genetics	Draft Genome Sequence of Tannerella forsythia Type Strain ATCC 43037.	Friedrich V, Pabinger S, Chen T, Messner P, Dewhirst FE, Schaffer C	Genome Announc	10.1128/genomeA.00660-15	2015	*
Cultivation	Outer membrane vesicles of Tannerella forsythia: biogenesis, composition, and virulence.	Friedrich V, Gruber C, Nimeth I, Pabinger S, Sekot G, Posch G, Altmann F, Messner P, Andrukhov O, Schaffer C	Mol Oral Microbiol	10.1111/omi.12104	2015	*
Enzymology	Characterization of an alpha-l-fucosidase from the periodontal pathogen Tannerella forsythia.	Megson ZA, Koerdt A, Schuster H, Ludwig R, Janesch B, Frey A, Naylor K, Wilson IB, Stafford GP, Messner P, Schaffer C	Virulence	10.1080/21505594.2015.1010982	2015	*
Pathogenicity	Chronic oral infection with major periodontal bacteria Tannerella forsythia modulates systemic atherosclerosis risk factors and inflammatory markers.	Chukkapalli SS, Rivera-Kweh MF, Velsko IM, Chen H, Zheng D, Bhattacharyya I, Gangula PR, Lucas AR, Kesavalu L	Pathog Dis	10.1093/femspd/ftv009	2015	*
Metabolism	A hybrid two-component system of Tannerella forsythia affects autoaggregation and post-translational modification of surface proteins.	Niwa D, Nishikawa K, Nakamura H	FEMS Microbiol Lett	10.1111/j.1574-6968.2011.02256.x	2011	*
Pathogenicity	Potential of the Tannerella forsythia S-layer to delay the immune response.	Sekot G, Posch G, Messner P, Matejka M, Rausch-Fan X, Andrukhov O, Schaffer C	J Dent Res	10.1177/0022034510384622	2010	*
Enzymology	A novel matrix metalloprotease-like enzyme (karilysin) of the periodontal pathogen Tannerella forsythia ATCC 43037.	Karim AY, Kulczycka M, Kantyka T, Dubin G, Jabaiah A, Daugherty PS, Thogersen IB, Enghild JJ, Nguyen KA, Potempa J	Biol Chem	10.1515/BC.2010.009	2010	*
Pathogenicity	Loss of adherence ability to human gingival epithelial cells in S-layer protein-deficient mutants of Tannerella forsythensis.	Sakakibara J, Nagano K, Murakami Y, Higuchi N, Nakamura H, Shimozato K, Yoshimura F	Microbiology (Reading)	10.1099/mic.0.29275-0	2007	*
Phylogeny	Isolation and identification of a cytopathic activity in Tannerella forsythia.	Nakajima T, Tomi N, Fukuyo Y, Ishikura H, Ohno Y, Arvind R, Arai T, Ishikawa I, Arakawa S	Biochem Biophys Res Commun	10.1016/j.bbrc.2006.10.012	2006	*
Enzymology	[Separation of Bacteroides forsythus ATCC43037 proteins by horizontal two-dimensional gel electrophoresis].	Huang DM, Zhou XD, Kuboniwa M, Amano A	Hua Xi Kou Qiang Yi Xue Za Zhi		2004	*
Enzymology	Cloning of the Tannerella forsythensis (Bacteroides forsythus) siaHI gene and purification of the sialidase enzyme.	Ishikura H, Arakawa S, Nakajima T, Tsuchida N, Ishikawa I	J Med Microbiol	10.1099/jmm.0.05349-0	2003	*
Genetics	Distribution of Bacteroides forsythus genotypes in a Japanese periodontitis population.	Huang Y, Umeda M, Takeuchi Y, Ishizuka M, Yano-Higuchi K, Ishikawa I	Oral Microbiol Immunol	10.1034/j.1399-302x.2003.00060.x	2003	*
Enzymology	[Cloning and sequence analysis of a sialidase gene (siaHI) from Bacteroides forsythus ATCC 43037].	Ishikura H	Kokubyo Gakkai Zasshi	10.5357/koubyou.69.119	2002	*
Genetics	Bacteroides forsythus prtH genotype in periodontitis patients: occurrence and association with periodontal disease.	Tan KS, Song KP, Ong G	J Periodontal Res	10.1034/j.1600-0765.2001.360608.x	2001	*
Pathogenicity	Adherence of Bacteroides forsythus to host cells.	Munemasa T, Takemoto T, Dahlen G, Hino T, Shiba H, Ogawa T, Kurihara H	Microbios		2000	*
Phylogeny	Characterization of Bacteroides forsythus strains from cat and dog bite wounds in humans and comparison with monkey and human oral strains.	Hudspeth MK, Hunt Gerardo S, Maiden MF, Citron DM, Goldstein EJ	J Clin Microbiol	10.1128/JCM.37.6.2003-2006.1999	1999	*
Enzymology	Cloning, expression, and sequencing of a cell surface antigen containing a leucine-rich repeat motif from Bacteroides forsythus ATCC 43037.	Sharma A, Sojar HT, Glurich I, Honma K, Kuramitsu HK, Genco RJ	Infect Immun	10.1128/IAI.66.12.5703-5710.1998	1998	*
Enzymology	Cloning, expression, and sequencing of a protease gene from Bacteroides forsythus ATCC 43037 in Escherichia coli.	Saito T, Ishihara K, Kato T, Okuda K	Infect Immun	10.1128/iai.65.11.4888-4891.1997	1997	*
	Identification of protein targets in red complex organisms binding with resveratrol.	Pothapur KK, Vishnu Priya V, Rengasamy G, Jayaseelan VP	Bioinformation	10.6026/97320630016837	2020	*
	Protein targets in the red complex organisms binding with an herbal compound silymarin.	Faiz N, Pothapur KK, Vishnupriya V, Gayathri R, Priyadharsini JV	Bioinformation	10.6026/97320630016759	2020	*
	Identification of aspirin and diclofenac binding proteins in the red complex pathogens.	Babu G, Priya VV, Krishnaa PK, Gayathri R, Priyadharsini JV	Bioinformation	10.6026/97320630017192	2021	*
	Effect of azithromycin on a red complex polymicrobial biofilm.	Ong HS, Oettinger-Barak O, Dashper SG, Darby IB, Tan KH, Reynolds EC	J Oral Microbiol	10.1080/20002297.2017.1339579	2017	*
	A General Protein O-Glycosylation Gene Cluster Encodes the Species-Specific Glycan of the Oral Pathogen Tannerella forsythia: O-Glycan Biosynthesis and Immunological Implications.	Tomek MB, Maresch D, Windwarder M, Friedrich V, Janesch B, Fuchs K, Neumann L, Nimeth I, Zwickl NF, Dohm JC, Everest-Dass A, Kolarich D, Himmelbauer H, Altmann F, Schaffer C	Front Microbiol	10.3389/fmicb.2018.02008	2018	*
	KLIKK proteases of Tannerella forsythia: putative virulence factors with a unique domain structure.	Ksiazek M, Mizgalska D, Eick S, Thogersen IB, Enghild JJ, Potempa J	Front Microbiol	10.3389/fmicb.2015.00312	2015	*
	Glucose toxicity effect and accumulation of methylglyoxal by the periodontal anaerobe Bacteroides forsythus.	Maiden MF, Pham C, Kashket S	Anaerobe	10.1016/j.anaerobe.2003.12.001	2004	*

References

#20215

Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 )

#47258 Culture Collection University of Gothenburg (CCUG) ; Curators of the CCUG; CCUG 21028 A

#66792

Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) .

#67770 Japan Collection of Microorganism (JCM) ; Curators of the JCM;

#69479

João F Matias Rodrigues, Janko Tackmann,Gregor Rot, Thomas SB Schmidt, Lukas Malfertheiner, Mihai Danaila,Marija Dmitrijeva, Daniela Gaio, Nicolas Näpflin and Christian von Mering. University of Zurich.: MicrobeAtlas 1.0 beta .

#69480

Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Predictions based on genome sequence made in the Diaspora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) .

#69481

Xiao-Yin To, René Mreches, Martin Binder, Alice C. McHardy, Philipp C. Münch: Predictions based on the model GenomeNet Sporulation v. 1 . ( DOI 10.21203/rs.3.rs-2527258/v1 )

#99022

Reimer, L.C., Lissin, A.,Schober, I., Witte,J.F., Podstawka, A., Lüken, H., Bunk, B.,Overmann, J.: StrainInfo: A central database for resolving microbial strain identifiers . ( DOI 10.60712/SI-ID41611.1 )

#124043

Dr. Isabel Schober, Dr. Julia Koblitz: Data extracted from sequence databases, automatically matched based on designation and taxonomy .

* These data were automatically processed and therefore are not curated

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Tannerella forsythia KS16

Tannerella forsythia 3313

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