Strain identifier
BacDive ID: 5765
Type strain: 
Species: Fusobacterium nucleatum
Strain Designation: 1612A
Strain history: CIP <- 1984, ATCC <- W.E.C. Moore: strain VPI 4355 <- A.R. Prévot, Inst. Pasteur, Paris, France: strain 1612A
NCBI tax ID(s): 190304 (strain), 851 (species)
version 8.1 (current version)
General
@ref: 6013
BacDive-ID: 5765
DSM-Number: 15643
keywords: genome sequence, 16S sequence, Bacteria, anaerobe, mesophilic, Gram-negative
description: Fusobacterium nucleatum 1612A is an anaerobe, mesophilic, Gram-negative bacterium that was isolated from cervico-facial lesion.
NCBI tax id
| NCBI tax id | Matching level |
|---|---|
| 851 | species |
| 190304 | strain |
strain history
| @ref | history |
|---|---|
| 6013 | <- J. Tang, ATCC <- W. E. C. Moore <- A. Prevot |
| 67770 | Tokyo Med. Dent. Univ. <-- Tama Biochem. Co., Ltd. <-- ATCC 25586 <-- W. E. C. Moore VPI 4355 <-- A. Prévot 1210. |
| 121367 | CIP <- 1984, ATCC <- W.E.C. Moore: strain VPI 4355 <- A.R. Prévot, Inst. Pasteur, Paris, France: strain 1612A |
doi: 10.13145/bacdive5765.20230509.8.1
Name and taxonomic classification
LPSN
- @ref: 20215
- description: domain/bacteria
- keyword: phylum/fusobacteriota
- domain: Bacteria
- phylum: Fusobacteriota
- class: Fusobacteriia
- order: Fusobacteriales
- family: Fusobacteriaceae
- genus: Fusobacterium
- species: Fusobacterium nucleatum
- full scientific name: Fusobacterium nucleatum Knorr 1922 (Approved Lists 1980)
@ref: 6013
domain: Bacteria
phylum: Fusobacteria
class: Fusobacteriia
order: Fusobacteriales
family: Fusobacteriaceae
genus: Fusobacterium
species: Fusobacterium nucleatum subsp. nucleatum
full scientific name: Fusobacterium nucleatum subsp. nucleatum (Knorr 1922) Dzink et al. 1990
strain designation: 1612A
type strain: yes
Morphology
cell morphology
| @ref | gram stain | confidence | cell shape | motility |
|---|---|---|---|---|
| 69480 | negative | 99.75 | ||
| 121367 | negative | rod-shaped | no |
colony morphology
| @ref | incubation period |
|---|---|
| 6013 | 1-2 days |
| 121367 |
Culture and growth conditions
culture medium
| @ref | name | growth | link | composition |
|---|---|---|---|---|
| 6013 | COLUMBIA BLOOD MEDIUM (DSMZ Medium 693) | yes | https://mediadive.dsmz.de/medium/693 | Name: COLUMBIA BLOOD MEDIUM (DSMZ Medium 693) Composition: Defibrinated sheep blood 50.0 g/l Columbia agar base |
| 6013 | PYG MEDIUM (MODIFIED) (DSMZ Medium 104) | yes | https://mediadive.dsmz.de/medium/104 | Name: PYG MEDIUM (modified) (DSMZ Medium 104) Composition: Yeast extract 10.0 g/l Peptone 5.0 g/l Trypticase peptone 5.0 g/l Beef extract 5.0 g/l Glucose 5.0 g/l L-Cysteine HCl x H2O 0.5 g/l NaHCO3 0.4 g/l NaCl 0.08 g/l K2HPO4 0.04 g/l KH2PO4 0.04 g/l MgSO4 x 7 H2O 0.02 g/l CaCl2 x 2 H2O 0.01 g/l Hemin 0.005 g/l Ethanol 0.0038 g/l Resazurin 0.001 g/l Tween 80 Vitamin K1 NaOH Distilled water |
| 35308 | MEDIUM 20 - for Anaerobic bacteria | yes | Agar (15.000 g);Glucose (5.000 g);Yeast extract (20.000 g);Tryptone (30.000 g);Cysteine hydrochloride (0.500 g);distilled water (1000.000 ml);Hemin solution -M00149 (25.000 ml) | |
| 121367 | CIP Medium 45 | yes | https://catalogue-crbip.pasteur.fr/fiche_milieu.xhtml?crbip=45 | |
| 121367 | CIP Medium 20 | yes | https://catalogue-crbip.pasteur.fr/fiche_milieu.xhtml?crbip=20 |
culture temp
| @ref | growth | type | temperature | range |
|---|---|---|---|---|
| 6013 | positive | growth | 37 | mesophilic |
| 35308 | positive | growth | 37 | mesophilic |
| 67770 | positive | growth | 37 | mesophilic |
Physiology and metabolism
oxygen tolerance
| @ref | oxygen tolerance | confidence |
|---|---|---|
| 6013 | anaerobe | |
| 69480 | anaerobe | 99.612 |
| 121367 | anaerobe |
spore formation
- @ref: 69480
- spore formation: no
- confidence: 99.99
metabolite utilization
| @ref | metabolite | utilization activity | kind of utilization tested | Chebi-ID |
|---|---|---|---|---|
| 68371 | Potassium 5-ketogluconate | - | builds acid from | |
| 68371 | Potassium 2-ketogluconate | - | builds acid from | |
| 68371 | gluconate | - | builds acid from | 24265 |
| 68371 | L-arabitol | - | builds acid from | 18403 |
| 68371 | D-arabitol | - | builds acid from | 18333 |
| 68371 | L-fucose | - | builds acid from | 18287 |
| 68371 | D-fucose | - | builds acid from | 28847 |
| 68371 | D-tagatose | - | builds acid from | 16443 |
| 68371 | D-lyxose | - | builds acid from | 62318 |
| 68371 | turanose | - | builds acid from | 32528 |
| 68371 | gentiobiose | - | builds acid from | 28066 |
| 68371 | xylitol | - | builds acid from | 17151 |
| 68371 | glycogen | - | builds acid from | 28087 |
| 68371 | starch | - | builds acid from | 28017 |
| 68371 | raffinose | - | builds acid from | 16634 |
| 68371 | melezitose | - | builds acid from | 6731 |
| 68371 | inulin | - | builds acid from | 15443 |
| 68371 | trehalose | - | builds acid from | 27082 |
| 68371 | sucrose | - | builds acid from | 17992 |
| 68371 | melibiose | - | builds acid from | 28053 |
| 68371 | lactose | - | builds acid from | 17716 |
| 68371 | maltose | - | builds acid from | 17306 |
| 68371 | cellobiose | - | builds acid from | 17057 |
| 68371 | salicin | - | builds acid from | 17814 |
| 68371 | esculin | - | builds acid from | 4853 |
| 68371 | arbutin | - | builds acid from | 18305 |
| 68371 | amygdalin | - | builds acid from | 27613 |
| 68371 | N-acetylglucosamine | - | builds acid from | 59640 |
| 68371 | methyl alpha-D-glucopyranoside | - | builds acid from | 320061 |
| 68371 | methyl alpha-D-mannoside | - | builds acid from | 43943 |
| 68371 | D-sorbitol | - | builds acid from | 17924 |
| 68371 | D-mannitol | - | builds acid from | 16899 |
| 68371 | myo-inositol | - | builds acid from | 17268 |
| 68371 | galactitol | - | builds acid from | 16813 |
| 68371 | L-rhamnose | - | builds acid from | 62345 |
| 68371 | L-sorbose | - | builds acid from | 17266 |
| 68371 | D-mannose | - | builds acid from | 16024 |
| 68371 | D-fructose | - | builds acid from | 15824 |
| 68371 | D-glucose | - | builds acid from | 17634 |
| 68371 | D-galactose | - | builds acid from | 12936 |
| 68371 | methyl beta-D-xylopyranoside | - | builds acid from | 74863 |
| 68371 | ribitol | - | builds acid from | 15963 |
| 68371 | L-xylose | - | builds acid from | 65328 |
| 68371 | D-xylose | - | builds acid from | 65327 |
| 68371 | D-ribose | - | builds acid from | 16988 |
| 68371 | L-arabinose | - | builds acid from | 30849 |
| 68371 | D-arabinose | - | builds acid from | 17108 |
| 68371 | erythritol | - | builds acid from | 17113 |
| 68371 | glycerol | - | builds acid from | 17754 |
| 121367 | D-arabinose | - | degradation | 17108 |
| 121367 | D-fructose | - | degradation | 15824 |
| 121367 | D-glucose | - | degradation | 17634 |
| 121367 | D-xylose | - | degradation | 65327 |
| 121367 | cellobiose | - | degradation | 17057 |
| 121367 | lactose | - | degradation | 17716 |
| 121367 | maltose | - | degradation | 17306 |
| 121367 | salicin | - | degradation | 17814 |
| 121367 | sucrose | - | degradation | 17992 |
| 121367 | esculin | - | hydrolysis | 4853 |
| 121367 | nitrate | - | reduction | 17632 |
| 121367 | nitrite | - | reduction | 16301 |
| 121367 | nitrate | + | respiration | 17632 |
| 68380 | urea | - | hydrolysis | 16199 |
| 68380 | arginine | - | hydrolysis | 29016 |
| 68380 | D-mannose | - | fermentation | 16024 |
| 68380 | raffinose | - | fermentation | 16634 |
| 68380 | L-glutamate | - | degradation | 29985 |
metabolite production
- @ref: 121367
- Chebi-ID: 35581
- metabolite: indole
- production: yes
enzymes
| @ref | value | activity | ec |
|---|---|---|---|
| 68382 | alpha-fucosidase | - | 3.2.1.51 |
| 68382 | alpha-mannosidase | - | 3.2.1.24 |
| 68382 | N-acetyl-beta-glucosaminidase | - | 3.2.1.52 |
| 68382 | beta-glucosidase | - | 3.2.1.21 |
| 68382 | alpha-glucosidase | + | 3.2.1.20 |
| 68382 | beta-glucuronidase | - | 3.2.1.31 |
| 68382 | beta-galactosidase | - | 3.2.1.23 |
| 68382 | alpha-galactosidase | - | 3.2.1.22 |
| 68382 | naphthol-AS-BI-phosphohydrolase | + | |
| 68382 | acid phosphatase | + | 3.1.3.2 |
| 68382 | alpha-chymotrypsin | - | 3.4.21.1 |
| 68382 | trypsin | - | 3.4.21.4 |
| 68382 | cystine arylamidase | - | 3.4.11.3 |
| 68382 | valine arylamidase | - | |
| 68382 | leucine arylamidase | + | 3.4.11.1 |
| 68382 | lipase (C 14) | - | |
| 68382 | esterase lipase (C 8) | + | |
| 68382 | esterase (C 4) | + | |
| 68382 | alkaline phosphatase | - | 3.1.3.1 |
| 68380 | serine arylamidase | - | |
| 68380 | glutamyl-glutamate arylamidase | - | |
| 68380 | histidine arylamidase | - | |
| 68380 | glycin arylamidase | - | |
| 68380 | alanine arylamidase | - | 3.4.11.2 |
| 68380 | tyrosine arylamidase | - | |
| 68380 | pyrrolidonyl arylamidase | - | 3.4.19.3 |
| 68380 | leucine arylamidase | - | 3.4.11.1 |
| 68380 | phenylalanine arylamidase | - | |
| 68380 | leucyl glycin arylamidase | - | 3.4.11.1 |
| 68380 | proline-arylamidase | - | 3.4.11.5 |
| 68380 | L-arginine arylamidase | - | |
| 68380 | alkaline phosphatase | - | 3.1.3.1 |
| 68380 | alpha-fucosidase | - | 3.2.1.51 |
| 68380 | glutamate decarboxylase | - | 4.1.1.15 |
| 68380 | N-acetyl-beta-glucosaminidase | - | 3.2.1.52 |
| 68380 | beta-glucuronidase | - | 3.2.1.31 |
| 68380 | alpha-arabinosidase | - | 3.2.1.55 |
| 68380 | beta-glucosidase | - | 3.2.1.21 |
| 68380 | alpha-glucosidase | - | 3.2.1.20 |
| 68380 | beta-Galactosidase 6-phosphate | - | |
| 68380 | beta-galactosidase | - | 3.2.1.23 |
| 68380 | alpha-galactosidase | - | 3.2.1.22 |
| 68380 | arginine dihydrolase | - | 3.5.3.6 |
| 68380 | urease | - | 3.5.1.5 |
| 121367 | oxidase | - | |
| 121367 | beta-galactosidase | + | 3.2.1.23 |
| 121367 | alcohol dehydrogenase | - | 1.1.1.1 |
| 121367 | gelatinase | - | |
| 121367 | amylase | - | |
| 121367 | DNase | - | |
| 121367 | caseinase | - | 3.4.21.50 |
| 121367 | catalase | - | 1.11.1.6 |
| 121367 | tween esterase | - | |
| 121367 | lecithinase | + | |
| 121367 | lipase | - | |
| 121367 | lysine decarboxylase | - | 4.1.1.18 |
| 121367 | ornithine decarboxylase | - | 4.1.1.17 |
| 121367 | protease | + | |
| 121367 | urease | - | 3.5.1.5 |
fatty acid profile
fatty acids
@ref fatty acid percentage ECL 65615 C12:0 0.7 12 65615 C14:0 29.4 14 65615 C15:0 0.9 15 65615 C16:0 19 16 65615 C18:0 2 18 65615 C13:0 3OH/C15:1 i I/H 2.4 14.469 65615 C13:1 at 12-13 0.7 12.931 65615 C14:0 3OH/C16:1 ISO I 5.4 15.485 65615 C16:0 3OH 7.1 17.52 65615 C16:0 aldehyde 1.7 14.949 65615 C16:1 ω7c 8.1 15.819 65615 C16:1 ω7c DMA 0.8 16.288 65615 C17:1 ISO I/C16:0 DMA 6.7 16.481 65615 C18:1 ω7c /12t/9t 1.9 17.824 65615 C18:1 ω9c 5.3 17.769 65615 C18:2 ω6,9c/C18:0 ANTE 8 17.724 - type of FA analysis: whole cell analysis
- method/protocol: CCUG
API zym
| @ref | Control | Alkaline phosphatase | Esterase | Esterase Lipase | Lipase | Leucine arylamidase | Valine arylamidase | Cystine arylamidase | Trypsin | alpha- Chymotrypsin | Acid phosphatase | Naphthol-AS-BI-phosphohydrolase | alpha- Galactosidase | beta- Galactosidase | beta- Glucuronidase | alpha- Glucosidase | beta- Glucosidase | N-acetyl-beta- glucosaminidase | alpha- Mannosidase | alpha- Fucosidase |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 121367 | - | - | + | + | - | + | - | - | - | - | + | + | - | - | - | + | - | - | - | - |
API 50CHac
| @ref | GLY | ERY | DARA | LARA | RIB | DXYL | LXYL | ADO | MDX | GAL | GLU | FRU | MNE | SBE | RHA | DUL | INO | MAN | SOR | MDM | MDG | NAG | AMY | ARB | ESC | SAL | CEL | MAL | LAC | MEL | SAC | TRE | INU | MLZ | RAF | AMD | GLYG | XLT | GEN | TUR | LYX | TAG | DFUC | LFUC | DARL | LARL | GNT | 2KG | 5KG |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 121367 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
API rID32A
| @ref | URE | ADH Arg | alpha GAL | beta GAL | beta GP | alpha GLU | beta GLU | alpha ARA | beta GUR | beta NAG | MNE | RAF | GDC | alpha FUC | NIT | IND | PAL | ArgA | ProA | LGA | PheA | LeuA | PyrA | TyrA | AlaA | GlyA | HisA | GGA | SerA |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 6013 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | + | - | - | - | - | - | - | - | - | - | - | - | - | - |
| 6013 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | + | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| 6013 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | + | - | - | - | - | - | - | - | - | - | - | - | - | - |
| 6013 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | + | - | - | - | - | - | - | - | - | - | - | - | - | - |
| 6013 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | + | - | - | - | - | - | - | - | - | - | - | - | - | - |
| 6013 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | + | - | - | - | - | - | - | - | - | - | - | - | - | - |
| 6013 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | + | - | - | - | - | - | - | - | - | - | - | - | - | - |
| 6013 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | + | - | - | - | - | - | - | - | - | - | - | - | - | - |
| 6013 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | + | - | - | - | - | - | - | - | - | - | - | - | - | - |
| 6013 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | + | - | - | - | - | - | - | - | - | - | - | - | - | - |
Isolation, sampling and environmental information
isolation
| @ref | sample type |
|---|---|
| 6013 | cervico-facial lesion |
| 67770 | Cervico-facial lesion |
| 121367 | Human, Cervico-facial lesion |
isolation source categories
| Cat1 | Cat2 | Cat3 |
|---|---|---|
| #Host Body-Site | #Oral cavity and airways | #Throat |
| #Host Body-Site | #Other | #Wound |
taxonmaps
- @ref: 69479
- File name: preview.99_1338.png
- url: https://microbeatlas.org/index.html?action=taxon&taxon_id=90_140;96_436;97_498;98_572;99_1338&stattab=map
- Last taxonomy: Fusobacterium nucleatum
- 16S sequence: GQ301038
- Sequence Identity:
- Total samples: 3612
- soil counts: 15
- aquatic counts: 188
- animal counts: 3393
- plant counts: 16
Safety information
risk assessment
| @ref | biosafety level | biosafety level comment |
|---|---|---|
| 6013 | 2 | Risk group (German classification) |
| 121367 | 1 | Risk group (French classification) |
Sequence information
16S sequences
| @ref | description | accession | length | database | NCBI tax ID |
|---|---|---|---|---|---|
| 20218 | Fusobacterium nucleatum subsp. nucleatum gene for 16S ribosomal RNA, partial sequence, strain: JCM 8532 | AB573068 | 1481 | ena | 190304 |
| 20218 | Fusobacterium nucleatum subsp. nucleatum strain ATCC 25586 16S ribosomal RNA gene, partial sequence; internal transcribed spacer 1, complete sequence; and 23S ribosomal RNA gene, partial sequence | AF342829 | 745 | ena | 190304 |
| 20218 | Fusobacterium nucleatum subsp. nucleatum 16S ribosomal RNA gene | AJ133496 | 1479 | ena | 190304 |
| 20218 | Fusobacterium nucleatum subsp. nucleatum strain ATCC 25586 16S ribosomal RNA gene, partial sequence | GQ301038 | 1442 | ena | 190304 |
| 20218 | Fusobacterium nucleatum subsp. nucleatum ATCC 25586 clone C1_short_clone2 16S ribosomal RNA gene, partial sequence; 16S-23S ribosomal RNA intergenic spacer, complete sequence; and 23S ribosomal RNA gene, partial sequence | JQ724660 | 1023 | ena | 190304 |
| 20218 | Fusobacterium nucleatum subsp. nucleatum ATCC 25586 clone C1_short_clone4 16S ribosomal RNA gene, partial sequence; 16S-23S ribosomal RNA intergenic spacer, complete sequence; and 23S ribosomal RNA gene, partial sequence | JQ724661 | 1023 | ena | 190304 |
| 20218 | Fusobacterium nucleatum subsp. nucleatum ATCC 25586 clone C1_short_clone5 16S ribosomal RNA gene, partial sequence; 16S-23S ribosomal RNA intergenic spacer, complete sequence; and 23S ribosomal RNA gene, partial sequence | JQ724662 | 1023 | ena | 190304 |
| 20218 | Fusobacterium nucleatum subsp. nucleatum ATCC 25586 clone A1_long_clone7 16S ribosomal RNA gene, partial sequence; 16S-23S ribosomal RNA intergenic spacer, complete sequence; and 23S ribosomal RNA gene, partial sequence | JQ724663 | 1199 | ena | 190304 |
| 20218 | Fusobacterium nucleatum subsp. nucleatum ATCC 25586 clone C1_short_clone8 16S ribosomal RNA gene, partial sequence; 16S-23S ribosomal RNA intergenic spacer, complete sequence; and 23S ribosomal RNA gene, partial sequence | JQ724664 | 1023 | ena | 190304 |
| 20218 | Fusobacterium nucleatum subsp. nucleatum ATCC 25586 clone C1_short_clone13 16S ribosomal RNA gene, partial sequence; 16S-23S ribosomal RNA intergenic spacer, complete sequence; and 23S ribosomal RNA gene, partial sequence | JQ724665 | 1023 | ena | 190304 |
| 20218 | Fusobacterium nucleatum subsp. nucleatum ATCC 25586 clone C1_short_clone14 16S ribosomal RNA gene, partial sequence; 16S-23S ribosomal RNA intergenic spacer, complete sequence; and 23S ribosomal RNA gene, partial sequence | JQ724666 | 1022 | ena | 190304 |
| 20218 | Fusobacterium nucleatum subsp. nucleatum ATCC 25586 clone C1_short_clone15 16S ribosomal RNA gene, partial sequence; 16S-23S ribosomal RNA intergenic spacer, complete sequence; and 23S ribosomal RNA gene, partial sequence | JQ724667 | 1023 | ena | 190304 |
| 20218 | Fusobacterium nucleatum subsp. nucleatum ATCC 25586 clone A1_long_clone16 16S ribosomal RNA gene, partial sequence; 16S-23S ribosomal RNA intergenic spacer, complete sequence; and 23S ribosomal RNA gene, partial sequence | JQ724668 | 1200 | ena | 190304 |
| 20218 | Fusobacterium nucleatum subsp. nucleatum ATCC 25586 clone C1_short_clone17 16S ribosomal RNA gene, partial sequence; 16S-23S ribosomal RNA intergenic spacer, complete sequence; and 23S ribosomal RNA gene, partial sequence | JQ724669 | 1023 | ena | 190304 |
| 20218 | Fusobacterium nucleatum subsp. nucleatum small subunit ribosomal RNA gene sequence | M58683 | 1522 | ena | 190304 |
| 20218 | Fusobacterium nucleatum subsp. nucleatum small subunit ribosomal RNA | X55401 | 1331 | ena | 190304 |
| 6013 | Fusobacterium nucleatum subsp. nucleatum ATCC 25586, section 65 of 197 of the complete genome | AE010523 | 11396 | ena | 190304 |
Genome sequences
| @ref | description | accession | assembly level | database | NCBI tax ID |
|---|---|---|---|---|---|
| 66792 | Fusobacterium nucleatum subsp. nucleatum ATCC 25586 | GCA_000007325 | complete | ncbi | 190304 |
| 66792 | Fusobacterium nucleatum subsp. nucleatum ATCC 25586 | 190304.8 | complete | patric | 190304 |
| 66792 | Fusobacterium nucleatum nucleatum ATCC 25586 | 637000117 | complete | img | 190304 |
Genome-based predictions
predictions
| trait | prediction | confidence | training_data |
|---|---|---|---|
| spore-forming | yes | 80 | no |
| motile | no | 92.065 | no |
| flagellated | no | 95.373 | no |
| gram-positive | no | 92.793 | no |
| anaerobic | yes | 99.578 | yes |
| halophile | no | 72.118 | no |
| spore-forming | no | 89.148 | no |
| glucose-util | yes | 81.822 | no |
| aerobic | no | 98.745 | no |
| thermophile | no | 98.178 | no |
| glucose-ferment | yes | 59.372 | no |
External links
@ref: 6013
culture collection no.: DSM 15643, ATCC 25586, CCUG 32989, CIP 101130, JCM 8532, LMG 13131, VPI 4355, BCRC 10681, CCUG 33059, KCTC 2640
straininfo link
- @ref: 75244
- straininfo: 92417
literature
| topic | Pubmed-ID | title | authors | journal | DOI | year | mesh | topic2 |
|---|---|---|---|---|---|---|---|---|
| Phylogeny | 2223601 | Proposal of three subspecies of Fusobacterium nucleatum Knorr 1922: Fusobacterium nucleatum subsp. nucleatum subsp. nov., comb. nov.; Fusobacterium nucleatum subsp. polymorphum subsp. nov., nom. rev., comb. nov.; and Fusobacterium nucleatum subsp. vincentii subsp. nov., nom. rev., comb. nov. | Dzink JL, Sheenan MT, Socransky SS | Int J Syst Bacteriol | 10.1099/00207713-40-1-74 | 1990 | Bacterial Proteins/analysis, DNA, Bacterial/genetics, Electrophoresis, Polyacrylamide Gel, Fusobacterium/analysis/*classification/genetics, Nucleic Acid Hybridization, Sequence Homology, Nucleic Acid, Species Specificity | Enzymology |
| Metabolism | 2323539 | Diisopropylfluorophosphate-binding proteins in the outer membrane of Fusobacterium nucleatum: strain variations. | Brokstad KA, Bakken V, Vasstrand EN, Jensen HB | FEMS Microbiol Lett | 10.1016/0378-1097(90)90289-3 | 1990 | Bacterial Outer Membrane Proteins/*metabolism, Fusobacterium/*metabolism, Isoflurophate/*metabolism, Molecular Weight, Species Specificity | Phylogeny |
| Cultivation | 2349450 | Growth conditions and outer membrane proteins of Fusobacterium nucleatum. | Bakken V, Hogh BT, Jensen HB | Scand J Dent Res | 10.1111/j.1600-0722.1990.tb00964.x | 1990 | Autoradiography, Bacterial Outer Membrane Proteins/*analysis/biosynthesis, Culture Media, Electrophoresis, Polyacrylamide Gel, Fusobacterium/*growth & development | Enzymology |
| Enzymology | 2636259 | Purification and partial characterization of a major outer-membrane protein of Fusobacterium nucleatum. | Bakken V, Aaro S, Jensen HB | J Gen Microbiol | 10.1099/00221287-135-12-3253 | 1989 | Amino Acid Sequence, Amino Acids/analysis, Bacterial Outer Membrane Proteins/immunology/*isolation & purification, Chromatography, Gel, Cross Reactions, Electrophoresis, Polyacrylamide Gel, Fusobacterium/*analysis/immunology, Molecular Sequence Data, Molecular Weight | Genetics |
| Enzymology | 2643582 | Structural analysis of lipopolysaccharides from Eikenella corrodens by use of murine monoclonal antibodies. | Kato T, Takazoe I, Okuda K | Infect Immun | 10.1128/iai.57.2.656-659.1989 | 1989 | Animals, *Antibodies, Monoclonal, Antigen-Antibody Reactions, Antigens, Bacterial/immunology/*isolation & purification, Bacteroides/*immunology, Carbohydrate Conformation, Eikenella corrodens/*immunology, Female, Lipopolysaccharides/immunology/*isolation & purification, Mice, Mice, Inbred BALB C | Phylogeny |
| Phylogeny | 3818097 | Production of monoclonal antibodies that recognize specific and cross-reactive antigens of Fusobacterium nucleatum. | Bird PS, Seymour GJ | Infect Immun | 10.1128/iai.55.3.771-777.1987 | 1987 | Animals, Antibodies, Bacterial/*immunology, Antibodies, Monoclonal/*immunology, Antigens, Bacterial/immunology, Cross Reactions, Enzyme-Linked Immunosorbent Assay, Fusobacterium/*immunology, Hybridomas, Mice, Mice, Inbred BALB C, Species Specificity | Biotechnology |
| Phylogeny | 6735473 | Immunoglobulin G response to subgingival gram-negative bacteria in human subjects. | Naito Y, Okuda K, Takazoe I | Infect Immun | 10.1128/iai.45.1.47-51.1984 | 1984 | Adult, *Antibody Formation, Bacteroides/immunology, Enzyme-Linked Immunosorbent Assay, Fusobacterium/immunology, Gingiva/*microbiology, Gram-Negative Bacteria/*immunology/isolation & purification, Humans, Immunoglobulin G/*analysis, Periodontitis/*microbiology, Reference Values, Species Specificity | Pathogenicity |
| Metabolism | 6811551 | Pathway of lysine degradation in Fusobacterium nucleatum. | Barker HA, Kahn JM, Hedrick L | J Bacteriol | 10.1128/jb.152.1.201-207.1982 | 1982 | Acetates/metabolism, Amino Acid Isomerases/metabolism, Amino Acid Oxidoreductases/metabolism, Ammonia-Lyases/metabolism, Butyrates/metabolism, Fermentation, Fusobacterium/enzymology/*metabolism, *Intramolecular Transferases, Lysine/*metabolism, Oxo-Acid-Lyases/metabolism | Enzymology |
| Pathogenicity | 7560233 | Effect of periodontal treatments on serum IgG antibody titers against periodontopathic bacteria. | Horibe M, Watanabe H, Ishikawa I | J Clin Periodontol | 10.1111/j.1600-051x.1995.tb00798.x | 1995 | Adult, Aggregatibacter actinomycetemcomitans/immunology, Alveolar Bone Loss/microbiology/surgery/therapy, Antibodies, Bacterial/*blood, Bacteria/*immunology, Capnocytophaga/immunology, Dental Scaling, Eikenella corrodens/immunology, Female, Fusobacterium nucleatum/immunology, Humans, Immunoglobulin G/*blood, Male, Middle Aged, Periodontal Pocket/microbiology/surgery/therapy, Periodontitis/*microbiology/surgery/*therapy, Porphyromonas gingivalis/immunology, Prevotella/immunology, Prevotella intermedia/immunology, Root Planing | |
| Enzymology | 7588760 | The Fusobacterium nucleatum major outer-membrane protein (FomA) forms trimeric, water-filled channels in lipid bilayer membranes. | Kleivdal H, Benz R, Jensen HB | Eur J Biochem | 10.1111/j.1432-1033.1995.310_1.x | 1995 | Bacterial Outer Membrane Proteins/*chemistry/isolation & purification, Cross-Linking Reagents, Diffusion, Electric Conductivity, Fusobacterium nucleatum/*chemistry, Ion Channels/*chemistry, Lipid Bilayers/*chemistry, Membrane Lipids/*chemistry, Molecular Structure, Porins/chemistry/isolation & purification, Protein Conformation, Water/chemistry | Phylogeny |
| Enzymology | 7988882 | Sizing the Fusobacterium nucleatum genome by pulsed-field gel electrophoresis. | Bolstad AI | FEMS Microbiol Lett | 10.1111/j.1574-6968.1994.tb07214.x | 1994 | Chromosome Mapping, Electrophoresis, Gel, Pulsed-Field, Fusobacterium nucleatum/classification/*genetics, *Genome, Bacterial, Restriction Mapping | Genetics |
| Genetics | 8041356 | Sequence variability of the 40-kDa outer membrane proteins of Fusobacterium nucleatum strains and a model for the topology of the proteins. | Bolstad AI, Tommassen J, Jensen HB | Mol Gen Genet | 10.1007/BF00280193 | 1994 | Amino Acid Sequence, Bacterial Outer Membrane Proteins/chemistry/*genetics, Base Sequence, DNA, Bacterial, Fusobacterium/*metabolism, Genetic Variation, Molecular Sequence Data, Protein Conformation, Sequence Homology, Amino Acid | Metabolism |
| Metabolism | 8502161 | Methylation of adenine and cytosine in some strains of Fusobacterium nucleatum. | Bolstad AI, Jensen HB | Microb Pathog | 10.1006/mpat.1993.1012 | 1993 | Adenine/*metabolism, Blotting, Southern, Cytosine/*metabolism, DNA, Bacterial/metabolism, Electrophoresis, Agar Gel, Fusobacterium nucleatum/*metabolism, Methylation, Polymerase Chain Reaction | Enzymology |
| 8941767 | Induction of systemic murine B-cell responses by Fusobacterium nucleatum and Porphyromonas gingivalis. | Nunes IP, Jonsson R, Jensen HB, Bakken V | Oral Microbiol Immunol | 10.1111/j.1399-302x.1996.tb00349.x | 1996 | Animals, Antibodies, Bacterial/*biosynthesis/blood, Antigens, Bacterial/chemistry/*immunology, B-Lymphocytes/*immunology, Bacterial Outer Membrane Proteins/chemistry/immunology, Bacterial Proteins/chemistry/immunology, Ecosystem, Enzyme-Linked Immunosorbent Assay/methods, Female, Fusobacterium nucleatum/*immunology, Immunoblotting, Lymphocyte Activation, Mice, Mice, Inbred BALB C, Porphyromonas gingivalis/*immunology, Spleen/cytology/immunology, Statistics, Nonparametric | ||
| Pathogenicity | 8999284 | Extraction and characterization of the smooth-type lipopolysaccharide from Fusobacterium nucleatum JCM 8532 and its biological activities. | Onoue S, Niwa M, Isshiki Y, Kawahara K | Microbiol Immunol | 10.1111/j.1348-0421.1996.tb01075.x | 1996 | Adult, Carbohydrates/analysis, Fibroblasts/pathology, Fusobacterium nucleatum/*chemistry, Gingivitis/etiology, Glucosamine/analogs & derivatives/analysis, Humans, Lipopolysaccharides/*chemistry/*isolation & purification/pharmacology, O Antigens/analysis/isolation & purification/pharmacology, Sugar Acids/analysis | Enzymology |
| Enzymology | 9467390 | Arbitrarily primed polymerase chain reaction fingerprinting and clonal analysis of oral Fusobacterium nucleatum isolates. | George KS, Reynolds MA, Falkler WA Jr | Oral Microbiol Immunol | 10.1111/j.1399-302x.1997.tb00382.x | 1997 | Bacterial Typing Techniques, Clone Cells, DNA Fingerprinting/*methods, DNA Primers, DNA Restriction Enzymes, DNA, Bacterial/*analysis, Electrophoresis, Gel, Pulsed-Field, Evaluation Studies as Topic, Fusobacterium nucleatum/classification/*genetics/isolation & purification, Genotype, Humans, Mouth/microbiology, Periodontitis/microbiology, *Random Amplified Polymorphic DNA Technique | Phylogeny |
| Pathogenicity | 9835745 | [A comparative in-vitro study of the bactericidal efficacy of sodium hypochlorite and chlorhexidine gluconate plus cetrimide on root canal anaerobic bacterial flora]. | D'Arcangelo C, Varvara G | Minerva Stomatol | 1998 | Anti-Bacterial Agents/*pharmacology, Bacteria, Anaerobic/*drug effects, Cetrimonium, Cetrimonium Compounds/*pharmacology, Chlorhexidine/*analogs & derivatives/pharmacology, Dental Pulp Cavity/*microbiology, Humans, Microbial Sensitivity Tests/methods/statistics & numerical data, Root Canal Irrigants/*pharmacology, Sodium Hypochlorite/*pharmacology, Time Factors | ||
| Pathogenicity | 10338189 | Abscess forming ability of streptococcus milleri group: synergistic effect with Fusobacterium nucleatum. | Nagashima H, Takao A, Maeda N | Microbiol Immunol | 10.1111/j.1348-0421.1999.tb02395.x | 1999 | Abscess/*microbiology/pathology, Animals, Disease Models, Animal, Fusobacterium/*pathogenicity, Fusobacterium Infections/microbiology, Humans, Mice, Mice, Inbred BALB C, Phagocytosis, Streptococcal Infections/microbiology, Streptococcus/*pathogenicity | |
| Pathogenicity | 11358538 | Kinetics of coaggregation of Porphyromonas gingivalis with Fusobacterium nucleatum using an automated microtiter plate assay. | Metzger Z, Featherstone LG, Ambrose WW, Trope M, Arnold RR | Oral Microbiol Immunol | 10.1034/j.1399-302x.2001.016003163.x | 2001 | Automation, Bacterial Adhesion/drug effects, *Bacteriological Techniques, Dose-Response Relationship, Drug, Fusobacterium nucleatum/classification/*cytology/drug effects, Galactose/administration & dosage/pharmacology, Humans, Kinetics, Porphyromonas gingivalis/classification/*cytology/drug effects, Sensitivity and Specificity, Statistics as Topic, Titrimetry | Enzymology |
| Metabolism | 11889109 | Genome sequence and analysis of the oral bacterium Fusobacterium nucleatum strain ATCC 25586. | Kapatral V, Anderson I, Ivanova N, Reznik G, Los T, Lykidis A, Bhattacharyya A, Bartman A, Gardner W, Grechkin G, Zhu L, Vasieva O, Chu L, Kogan Y, Chaga O, Goltsman E, Bernal A, Larsen N, D'Souza M, Walunas T, Pusch G, Haselkorn R, Fonstein M, Kyrpides N, Overbeek R | J Bacteriol | 10.1128/JB.184.7.2005-2018.2002 | 2002 | Amino Acids/metabolism, Bacterial Outer Membrane Proteins/metabolism, Biological Transport, Cell Division, Coenzymes/metabolism, DNA Repair, DNA Replication, DNA Transposable Elements, DNA, Bacterial/analysis, Drug Resistance, Bacterial, Fusobacterium nucleatum/*genetics/metabolism, *Genome, Bacterial, Lipid Metabolism, Lipopolysaccharides/metabolism, Mutagenesis, Insertional, Nucleotides/metabolism, *Protein Biosynthesis, Protons, Signal Transduction/physiology, *Transcription, Genetic, Virulence | Genetics |
| Pathogenicity | 11938715 | In vitro effect of intracanal medicaments on strict anaerobes by means of the broth dilution method. | Rosa OP, Torres SA, Ferreira CM, Ferreira FB | Pesqui Odontol Bras | 10.1590/s1517-74912002000100006 | 2002 | Bacteria, Anaerobic/*drug effects, Indicator Dilution Techniques, Reproducibility of Results, Root Canal Therapy/*methods, Therapeutic Irrigation | |
| Pathogenicity | 11985513 | Effect of Fusobacterium nucleatum on the T and B cell responses to Porphyromonas gingivalis in a mouse model. | Gemmell E, Bird PS, Carter CL, Drysdale KE, Seymour GJ | Clin Exp Immunol | 10.1046/j.1365-2249.2002.01852.x | 2002 | Animals, Antibodies, Bacterial/blood/immunology, Antibody Specificity, Antigens, Bacterial/immunology, B-Lymphocytes/*immunology, Bacteroidaceae Infections/blood/*immunology, Cross Reactions, Female, Fusobacterium Infections/blood/*immunology, Fusobacterium nucleatum/*immunology, Humans, Immunity, Mice, Mice, Inbred BALB C, Porphyromonas gingivalis/*immunology, T-Lymphocyte Subsets/*immunology | |
| Pathogenicity | 12238802 | Activity of endodontic antibacterial agents against selected anaerobic bacteria. | Ferreira CM, da Silva Rosa OP, Torres SA, Ferreira FB, Bernardinelli N | Braz Dent J | 10.1590/s0103-64402002000200008 | 2002 | Bacteria, Anaerobic/*drug effects, Bacteroides fragilis/drug effects, Calcium Hydroxide/pharmacology, Camphor/pharmacology, Castor Oil/pharmacology, Chlorhexidine/*analogs & derivatives/pharmacology, Chlorophenols/pharmacology, Clostridium perfringens/drug effects, Culture Media, Detergents/pharmacology, Disinfectants/*pharmacology, Drug Combinations, Fusobacterium nucleatum/drug effects, Humans, Microbial Sensitivity Tests, Prevotella/drug effects, Root Canal Irrigants/*pharmacology, Spectrophotometry | Cultivation |
| Pathogenicity | 12479628 | In vitro effect of laser irradiation on cementum-bound endotoxin isolated from periodontally diseased roots. | Liu CM, Shyu YC, Pei SC, Lan WH, Hou LT | J Periodontol | 10.1902/jop.2002.73.11.1260 | 2002 | Adult, Aggregatibacter actinomycetemcomitans/chemistry, Bacteroides/chemistry, Chi-Square Distribution, Dental Cementum/*microbiology, Endotoxins/*radiation effects, Humans, In Vitro Techniques, Interleukin-1/biosynthesis, *Laser Therapy, Limulus Test, Monocytes/metabolism, Neodymium, Periodontitis/*microbiology/*therapy, Porphyromonas gingivalis/chemistry, Statistics, Nonparametric, Treatment Failure | Metabolism |
| Pathogenicity | 12636253 | Serum antibodies of periodontitis patients compared to the lipopolysaccharides of Porphyromonas gingivalis and Fusobacterium nucleatum. | Onoue S, Imai T, Kumada H, Umemoto T, Kaca W, Isshiki Y, Kaneko A, Kawahara K | Microbiol Immunol | 10.1111/j.1348-0421.2003.tb02785.x | 2003 | Adult, Antibodies, Bacterial/*blood, Bacteroidaceae Infections/blood/*immunology/microbiology, Female, Fusobacterium Infections/blood/*immunology, Fusobacterium nucleatum/*immunology, Humans, Lipopolysaccharides/immunology, Male, Middle Aged, Periodontitis/blood/*immunology/microbiology, Porphyromonas gingivalis/*immunology | |
| Metabolism | 12799352 | Genome analysis of F. nucleatum sub spp vincentii and its comparison with the genome of F. nucleatum ATCC 25586. | Kapatral V, Ivanova N, Anderson I, Reznik G, Bhattacharyya A, Gardner WL, Mikhailova N, Lapidus A, Larsen N, D'Souza M, Walunas T, Haselkorn R, Overbeek R, Kyrpides N | Genome Res | 10.1101/gr.566003 | 2003 | ATP-Binding Cassette Transporters/metabolism, Amino Acids/biosynthesis, Bacterial Proteins/biosynthesis/metabolism, Bacteriophages/genetics, Carbon/metabolism, Cell Division/genetics, DNA Repair/genetics, DNA Replication/genetics, DNA Transposable Elements, Drug Resistance, Bacterial/genetics, Energy Metabolism/genetics, Fusobacterium nucleatum/enzymology/*genetics/metabolism/pathogenicity, *Genome, Bacterial, Heat-Shock Proteins, Lipids/biosynthesis, Lipopolysaccharides/chemistry/metabolism, Membrane Proteins/genetics, Peptide Biosynthesis/genetics, Peptide Hydrolases/metabolism, Phosphotransferases/metabolism, RNA, Bacterial/genetics, RNA, Ribosomal/genetics, RNA, Transfer/genetics, Signal Transduction/genetics, Species Specificity | Genetics |
| Metabolism | 15993836 | Protein secretion systems in Fusobacterium nucleatum: genomic identification of Type 4 piliation and complete Type V pathways brings new insight into mechanisms of pathogenesis. | Desvaux M, Khan A, Beatson SA, Scott-Tucker A, Henderson IR | Biochim Biophys Acta | 10.1016/j.bbamem.2005.05.002 | 2005 | Amino Acid Motifs, Amino Acid Sequence, Bacterial Physiological Phenomena, Base Sequence, Biofilms, Computational Biology/methods, Fimbriae, Bacterial/*metabolism, Fusobacterium/metabolism, Fusobacterium nucleatum/*genetics/*pathogenicity, Molecular Sequence Data, Open Reading Frames, Phylogeny, Protein Binding, Protein Conformation, Protein Sorting Signals, Protein Structure, Secondary, Protein Structure, Tertiary, Protein Transport, Sequence Homology, Amino Acid, Software, Virulence | Genetics |
| Metabolism | 16030227 | Identification and characterization of a novel adhesin unique to oral fusobacteria. | Han YW, Ikegami A, Rajanna C, Kawsar HI, Zhou Y, Li M, Sojar HT, Genco RJ, Kuramitsu HK, Deng CX | J Bacteriol | 10.1128/JB.187.15.5330-5340.2005 | 2005 | Adhesins, Bacterial/chemistry/genetics/*metabolism, Amino Acid Sequence, Animals, CHO Cells, Cell Line, Cricetinae, Fusobacterium nucleatum/genetics/growth & development/*metabolism, Gene Deletion, Humans, Molecular Sequence Data, Molecular Weight, Mutation, Sequence Alignment, Species Specificity | Pathogenicity |
| Pathogenicity | 16125361 | Enhanced pathogenicity of Fusobacterium nucleatum adapted to oxidative stress. | Silva VL, Diniz CG, Cara DC, Santos SG, Nicoli JR, Carvalho MA, Farias LM | Microb Pathog | 10.1016/j.micpath.2005.07.002 | 2005 | *Adaptation, Physiological, Animals, Body Weight, Fusobacterium Infections/pathology, Fusobacterium nucleatum/growth & development/*pathogenicity/ultrastructure, Humans, Liver/pathology, Mice, Organ Size, *Oxidative Stress, Spleen/pathology | Stress |
| Phylogeny | 16145547 | Development of strain-specific PCR primers based on a DNA probe Fu12 for the identification of fusobacterium nucleatum subsp. nucleatum ATCC 25586T. | Kim HS, Song SK, Yoo SY, Jin DC, Shin HS, Lim CK, Kim MS, Kim JS, Choe SJ, Kook JK | J Microbiol | 2257 | 2005 | Blotting, Southern, DNA Probes/chemistry/*genetics, DNA, Bacterial/chemistry/genetics/isolation & purification, Fusobacterium Infections/microbiology, Fusobacterium nucleatum/*genetics/isolation & purification, Humans, Luminescent Measurements, Periodontitis/microbiology, Polymerase Chain Reaction/*methods, Sensitivity and Specificity, Sequence Analysis, DNA, Species Specificity | Enzymology |
| Pathogenicity | 16673792 | Antimicrobial effect in vitro of chlorhexidine and calcium hydroxide impregnated gutta-percha points. | Bozza FL, Molgatini SL, Perez SB, Tejerina DP, Perez Tito RI, Kaplan AE | Acta Odontol Latinoam | 2005 | Anti-Infective Agents, Local/*pharmacology, Calcium Hydroxide/*pharmacology, Candida albicans/drug effects, Chlorhexidine/*pharmacology, Colony Count, Microbial, Culture Media, Enterococcus faecalis/drug effects, Fusobacterium nucleatum/drug effects, *Gutta-Percha, Humans, Hydrogen-Ion Concentration, Materials Testing, Oxygen, Porphyromonas gingivalis/drug effects, Prevotella intermedia/drug effects, *Root Canal Filling Materials, Staphylococcus aureus/drug effects, Streptococcus mutans/drug effects, Temperature, Time Factors | Cultivation | |
| Metabolism | 16806047 | Antimicrobial actions of benzimidazoles against the oral anaerobes Fusobacterium nucleatum and Prevotella intermedia. | Sheng J, Nguyen PT, Baldeck JD, Olsson J, Marquis RE | Arch Oral Biol | 10.1016/j.archoralbio.2006.05.002 | 2006 | 2-Pyridinylmethylsulfinylbenzimidazoles/*pharmacology, Amino Acids/metabolism, Aminopeptidases/antagonists & inhibitors, Anaerobiosis/physiology, Anti-Infective Agents/*pharmacology, Enzyme Inhibitors/pharmacology, Fermentation, Fructose/metabolism, Fusobacterium nucleatum/*drug effects/metabolism, Glucose, Glutamic Acid/metabolism, Humans, Hydrogen-Ion Concentration, Lansoprazole, Lysine/metabolism, Mouth/*microbiology, Oxygen/metabolism, Prevotella intermedia/*drug effects/metabolism, Serine/metabolism | Pathogenicity |
| Metabolism | 17120973 | Effects of sonicated Prevotella intermedia, Fusobacterium nucleatum and Lactobacillus casei extracts on interleukin-8 production by human dental pulp cells. | Thaweboon B, Thaweboon S, Choonharuangdej S, Suppakpatana P | Southeast Asian J Trop Med Public Health | 2006 | Adolescent, Adult, Bacterial Infections/*metabolism, Cell Survival, Cells, Cultured, Dental Pulp/metabolism/*microbiology, *Fusobacteria, Humans, Interleukin-8/*biosynthesis, *Lactobacillus casei, *Prevotella intermedia | Pathogenicity | |
| Enzymology | 17584449 | Physiological alterations of a Fusobacterium nucleatum strain exposed to oxidative stress. | da Silva VL, Diniz CG, dos Santos SG, Gomes RM, Nicoli JR, Magalhaes PP, Mendes EN, de Carvalho MA, Farias LM | J Appl Microbiol | 10.1111/j.1365-2672.2006.03236.x | 2007 | Adaptation, Physiological, Bacterial Proteins/metabolism, Bacterial Typing Techniques/methods, Electrophoresis, Gel, Two-Dimensional/methods, Fusobacterium nucleatum/classification/genetics/*physiology, Genetic Variation, Oxidative Stress/*physiology, Polymerase Chain Reaction/methods | Stress |
| Pathogenicity | 18312575 | Interactions between salivary Bifidobacterium adolescentis and other oral bacteria: in vitro coaggregation and coadhesion assays. | Nagaoka S, Hojo K, Murata S, Mori T, Ohshima T, Maeda N | FEMS Microbiol Lett | 10.1111/j.1574-6968.2008.01092.x | 2008 | Bacteria/drug effects/genetics/isolation & purification, *Bacterial Adhesion/drug effects, *Bacterial Physiological Phenomena/drug effects, Bifidobacterium/drug effects/genetics/isolation & purification/*physiology, Biofilms/drug effects/growth & development, Endopeptidase K/pharmacology, Fusobacterium nucleatum/drug effects/genetics/physiology, Hot Temperature, Humans, In Situ Hybridization, Fluorescence, Mouth/*microbiology, Saliva/*microbiology | Enzymology |
| Metabolism | 18793368 | Stimulation of epithelial cell matrix metalloproteinase (MMP-2, -9, -13) and interleukin-8 secretion by fusobacteria. | Gursoy UK, Kononen E, Uitto VJ | Oral Microbiol Immunol | 10.1111/j.1399-302X.2008.00453.x | 2008 | Blotting, Western, Cell Line, Epithelial Cells, Fusobacterium/classification/*physiology, Fusobacterium necrophorum/physiology, Fusobacterium nucleatum/physiology, Humans, Interleukin-8/analysis/*metabolism, Keratinocytes/*enzymology/microbiology, Matrix Metalloproteinase 1/analysis/metabolism, Matrix Metalloproteinase 13/analysis/metabolism, Matrix Metalloproteinase 9/analysis/metabolism, Matrix Metalloproteinases/analysis/*metabolism, Mouth/microbiology, Time Factors | Pathogenicity |
| Pathogenicity | 20350156 | Biofilm formation enhances the oxygen tolerance and invasiveness of Fusobacterium nucleatum in an oral mucosa culture model. | Gursoy UK, Pollanen M, Kononen E, Uitto VJ | J Periodontol | 10.1902/jop.2010.090664 | 2010 | Aerobiosis/physiology, Bacterial Adhesion/physiology, Bacterial Physiological Phenomena, Biofilms/*growth & development, Cell Proliferation, Cell Survival, Collagen, Colony Count, Microbial, Coloring Agents, Epithelial Cells/microbiology, Fibroblasts/microbiology, Fusobacterium nucleatum/*physiology, Humans, Keratinocytes/microbiology, Ki-67 Antigen/analysis, L-Lactate Dehydrogenase/analysis, Microbial Viability, Mouth Mucosa/cytology/*microbiology, *Oxygen, Tissue Culture Techniques | Enzymology |
| Pathogenicity | 20380884 | Mixture of periodontopathogenic bacteria influences interaction with KB cells. | Kirschbaum M, Schultze-Mosgau S, Pfister W, Eick S | Anaerobe | 10.1016/j.anaerobe.2010.03.009 | 2010 | *Bacterial Adhesion, Bacteroidetes/growth & development/*pathogenicity, Coculture Techniques, Epithelial Cells/immunology/*microbiology, Fusobacterium nucleatum/growth & development/*pathogenicity, Humans, Interleukins/*metabolism, KB Cells, Periodontal Diseases/*microbiology, Treponema denticola/growth & development/*pathogenicity | Metabolism |
| Metabolism | 20413556 | Production of hydrogen sulfide by two enzymes associated with biosynthesis of homocysteine and lanthionine in Fusobacterium nucleatum subsp. nucleatum ATCC 25586. | Yoshida Y, Ito S, Kamo M, Kezuka Y, Tamura H, Kunimatsu K, Kato H | Microbiology (Reading) | 10.1099/mic.0.039180-0 | 2010 | Alanine/*analogs & derivatives/biosynthesis, Ammonia/metabolism, Aspartate Aminotransferases/chemistry/genetics/*metabolism, Bacterial Proteins/chemistry/genetics/*metabolism, Cysteine Synthase/chemistry/genetics/*metabolism, Fusobacterium nucleatum/chemistry/enzymology/genetics/*metabolism, Homocysteine/*biosynthesis, Hydrogen Sulfide/*metabolism, Kinetics, Pyruvic Acid/metabolism, Substrate Specificity, Sulfides | Enzymology |
| Metabolism | 20472741 | Production of indole from L-tryptophan and effects of these compounds on biofilm formation by Fusobacterium nucleatum ATCC 25586. | Sasaki-Imamura T, Yano A, Yoshida Y | Appl Environ Microbiol | 10.1128/AEM.00166-10 | 2010 | Base Sequence, Biofilms/*drug effects/growth & development, Fusobacterium nucleatum/*drug effects/enzymology/*growth & development, Indoles/metabolism/*pharmacology, Molecular Sequence Data, Plankton/drug effects/growth & development, Recombinant Proteins/genetics/metabolism, Tryptophan/*metabolism/pharmacology, Tryptophanase/genetics/metabolism | Pathogenicity |
| Metabolism | 20847052 | Fusobacterium nucleatum-associated beta-defensin inducer (FAD-I): identification, isolation, and functional evaluation. | Gupta S, Ghosh SK, Scott ME, Bainbridge B, Jiang B, Lamont RJ, McCormick TS, Weinberg A | J Biol Chem | 10.1074/jbc.M110.133140 | 2010 | Bacterial Proteins/genetics/*isolation & purification/*metabolism, Blotting, Western, Cell Wall/metabolism, Cells, Cultured, Cloning, Molecular, Epithelial Cells/*metabolism, Fusobacterium Infections/genetics/*metabolism/microbiology, Fusobacterium nucleatum/genetics/isolation & purification, Gingiva/cytology/*metabolism, Humans, Immunity, Innate, Recombinant Proteins/genetics/*isolation & purification/*metabolism, Signal Transduction, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization, Toll-Like Receptor 2, beta-Defensins/*metabolism | Enzymology |
| Pathogenicity | 20849395 | Antimicrobial activity of sodium citrate against Streptococcus pneumoniae and several oral bacteria. | Nagaoka S, Murata S, Kimura K, Mori T, Hojo K | Lett Appl Microbiol | 10.1111/j.1472-765X.2010.02932.x | 2010 | Anti-Bacterial Agents/*pharmacology, Bacteria/*drug effects/isolation & purification, Bacterial Infections/microbiology, Citrates/*pharmacology, Humans, Microbial Sensitivity Tests, Mouth Diseases/*microbiology, Pneumococcal Infections/*microbiology, Sodium Citrate, Streptococcus pneumoniae/*drug effects/isolation & purification | Enzymology |
| Metabolism | 21383473 | Myrsinoic acid B inhibits the production of hydrogen sulfide by periodontal pathogens in vitro. | Ito S, Shimura S, Tanaka T, Yaegaki K | J Breath Res | 10.1088/1752-7155/4/2/026005 | 2010 | Alkenes/*pharmacology, Benzofurans/*pharmacology, Chlorides/pharmacology, Enzyme Inhibitors/*pharmacology, Fusobacterium nucleatum/*metabolism, Humans, Hydrogen Sulfide/*metabolism, Porphyromonas gingivalis/*metabolism, Sulfhydryl Compounds/*metabolism, Treponema denticola/metabolism, Zinc Compounds/pharmacology | Pathogenicity |
| Metabolism | 21493682 | Identification and enzymic analysis of a novel protein associated with production of hydrogen sulfide and L-serine from L-cysteine in Fusobacterium nucleatum subsp. nucleatum ATCC 25586. | Yoshida Y, Suwabe K, Nagano K, Kezuka Y, Kato H, Yoshimura F | Microbiology (Reading) | 10.1099/mic.0.048934-0 | 2011 | Bacterial Proteins/genetics/*metabolism, Chromatography, Gas, Chromatography, High Pressure Liquid, Cysteine/*metabolism, Cysteine Synthase/genetics/metabolism, Escherichia coli/genetics/growth & development/metabolism, Fusobacterium nucleatum/enzymology/genetics/*metabolism, Hydrogen Sulfide/*metabolism, Kinetics, Serine/*biosynthesis | Enzymology |
| Pathogenicity | 21692631 | A novel organotypic dento-epithelial culture model: effect of Fusobacterium nucleatum biofilm on B-defensin-2, -3, and LL-37 expression. | Gursoy UK, Pollanen M, Kononen E, Uitto VJ | J Periodontol | 10.1902/jop.2011.110177 | 2011 | Antimicrobial Cationic Peptides/*biosynthesis, Biofilms/growth & development, Coculture Techniques, Epithelium/*metabolism, Fusobacterium nucleatum/*physiology, Humans, *Organ Culture Techniques, Tooth/cytology, beta-Defensins/*biosynthesis | Metabolism |
| Metabolism | 21798982 | Identification of an L-methionine gamma-lyase involved in the production of hydrogen sulfide from L-cysteine in Fusobacterium nucleatum subsp. nucleatum ATCC 25586. | Suwabe K, Yoshida Y, Nagano K, Yoshimura F | Microbiology (Reading) | 10.1099/mic.0.051813-0 | 2011 | Bacterial Proteins/chemistry/genetics/*metabolism, Carbon-Sulfur Lyases/chemistry/genetics/*metabolism, Cysteine/*metabolism, Fusobacterium nucleatum/chemistry/*enzymology/genetics/metabolism, Hydrogen Sulfide/*metabolism, Kinetics | Enzymology |
| Pathogenicity | 21945879 | Synergy in biofilm formation between Fusobacterium nucleatum and Prevotella species. | Okuda T, Kokubu E, Kawana T, Saito A, Okuda K, Ishihara K | Anaerobe | 10.1016/j.anaerobe.2011.09.003 | 2011 | Amino Acids/pharmacology, Bacterial Adhesion/drug effects, Biofilms/drug effects/*growth & development, Carbohydrates/pharmacology, Chelating Agents/pharmacology, Coculture Techniques, Edetic Acid/pharmacology, Endopeptidase K/chemistry, Fusobacterium nucleatum/*physiology, Homoserine/analogs & derivatives/biosynthesis, Hot Temperature, Lactones, Prevotella/*physiology, Symbiosis/*physiology | Stress |
| 22203875 | In Vitro Antibacterial Activity of Galls of Quercus infectoria Olivier against Oral Pathogens. | Basri DF, Tan LS, Shafiei Z, Zin NM | Evid Based Complement Alternat Med | 10.1155/2012/632796 | 2011 | |||
| Pathogenicity | 22443519 | Human neutrophil defensins and their effect on epithelial cells. | Gursoy UK, Kononen E, Luukkonen N, Uitto VJ | J Periodontol | 10.1902/jop.2012.120017 | 2012 | Adult, Anti-Infective Agents/analysis/*pharmacology, Bacterial Adhesion/drug effects, Basement Membrane/pathology, Cell Adhesion/drug effects, Cell Death/drug effects, Cell Movement/drug effects, Cell Proliferation/drug effects, Cell Survival/drug effects, Chronic Periodontitis/pathology, Coated Materials, Biocompatible/chemistry, Dose-Response Relationship, Drug, Epithelial Attachment/drug effects/pathology, Epithelial Cells/drug effects/pathology, Female, Fibronectins/chemistry, Fusobacterium nucleatum/drug effects, Gingiva/*drug effects/pathology, Gingival Pocket/pathology, Humans, Keratinocytes/drug effects, Male, Middle Aged, Neutrophils/*physiology, Prevotella intermedia/drug effects, alpha-Defensins/analysis/*pharmacology | |
| Phylogeny | 22493171 | Fretibacterium fastidiosum gen. nov., sp. nov., isolated from the human oral cavity. | Vartoukian SR, Downes J, Palmer RM, Wade WG | Int J Syst Evol Microbiol | 10.1099/ijs.0.041038-0 | 2012 | Acetic Acid/metabolism, Bacteria/*classification/genetics/isolation & purification, Base Composition, Coculture Techniques, DNA, Bacterial/genetics, Fatty Acids/analysis, Humans, Molecular Sequence Data, Mouth/*microbiology, Periodontal Pocket/microbiology, *Phylogeny, Propionates/metabolism, RNA, Ribosomal, 16S/genetics, Sequence Analysis, DNA | Metabolism |
| Pathogenicity | 23023263 | Morphological, biochemical, physiological and molecular aspects of the response of Fusobacterium nucleatum exposed to subinhibitory concentrations of antimicrobials. | de Souza Filho JA, Diniz CG, Barbosa NB, de Freitas MC, Lopes Neves MS, da Gama Mazzei RN, Gameiro J, Coelho CM, da Silva VL | Anaerobe | 10.1016/j.anaerobe.2012.09.007 | 2012 | Anti-Bacterial Agents/*pharmacology, Bacterial Proteins/analysis, Bacterial Typing Techniques, Biofilms/drug effects/growth & development, Carbohydrate Metabolism/drug effects, Enzymes/metabolism, Fusobacterium nucleatum/cytology/*drug effects/genetics/physiology, Genotype, Microbial Sensitivity Tests, Polymorphism, Genetic, Proteome/analysis | Metabolism |
| 23049613 | Antibacterial Activity of Myristica fragrans against Oral Pathogens. | Shafiei Z, Shuhairi NN, Md Fazly Shah Yap N, Harry Sibungkil CA, Latip J | Evid Based Complement Alternat Med | 10.1155/2012/825362 | 2012 | |||
| Pathogenicity | 23404558 | Regulation of visfatin by microbial and biomechanical signals in PDL cells. | Nogueira AV, Nokhbehsaim M, Eick S, Bourauel C, Jager A, Jepsen S, Cirelli JA, Deschner J | Clin Oral Investig | 10.1007/s00784-013-0935-1 | 2013 | Biomechanical Phenomena, Enzyme-Linked Immunosorbent Assay, Fusobacterium nucleatum/isolation & purification/pathogenicity, Humans, Nicotinamide Phosphoribosyltransferase/*metabolism, Periodontal Ligament/*cytology/metabolism/microbiology, Real-Time Polymerase Chain Reaction | Metabolism |
| Pathogenicity | 24458367 | In vitro activity of Carvacrol against titanium-adherent oral biofilms and planktonic cultures. | Ciandrini E, Campana R, Federici S, Manti A, Battistelli M, Falcieri E, Papa S, Baffone W | Clin Oral Investig | 10.1007/s00784-013-1179-9 | 2014 | Anti-Infective Agents/*pharmacology, Bacteria/classification/*drug effects, Bacterial Adhesion/drug effects, Biofilms/*drug effects, Cymenes, Flow Cytometry, In Vitro Techniques, Microbial Sensitivity Tests, Monoterpenes/*pharmacology, Plankton/*drug effects, *Titanium | Phylogeny |
| Metabolism | 24976684 | Biomechanical loading modulates proinflammatory and bone resorptive mediators in bacterial-stimulated PDL cells. | Nogueira AV, Nokhbehsaim M, Eick S, Bourauel C, Jager A, Jepsen S, Rossa C Jr, Deschner J, Cirelli JA | Mediators Inflamm | 10.1155/2014/425421 | 2014 | Cells, Cultured, Cyclooxygenase 2/metabolism, Dinoprostone/metabolism, Enzyme-Linked Immunosorbent Assay, Fusobacterium nucleatum/*pathogenicity, Humans, Osteoprotegerin/metabolism, Periodontal Ligament/cytology/*metabolism/*microbiology, RANK Ligand/metabolism, Reverse Transcriptase Polymerase Chain Reaction | Pathogenicity |
| Pathogenicity | 25132418 | Increased proliferation and decreased membrane permeability as defense mechanisms of Fusobacterium nucleatum against human neutrophilic peptide-1. | Keskin M, Kononen E, Soderling E, Isik G, Firatli E, Uitto VJ, Gursoy UK | Anaerobe | 10.1016/j.anaerobe.2014.08.001 | 2014 | Biofilms/*growth & development, Cell Membrane/*physiology, Child, Female, Fusobacterium nucleatum/*drug effects/growth & development/metabolism/*physiology, Humans, Male, Middle Aged, *Permeability, Polysaccharides, Bacterial/metabolism, alpha-Defensins/*metabolism | Metabolism |
| Pathogenicity | 25357190 | Identification and characterization of fusolisin, the Fusobacterium nucleatum autotransporter serine protease. | Doron L, Coppenhagen-Glazer S, Ibrahim Y, Eini A, Naor R, Rosen G, Bachrach G | PLoS One | 10.1371/journal.pone.0111329 | 2014 | Amino Acid Sequence, Bacterial Proteins/chemistry/*metabolism, Fusobacterium nucleatum/*enzymology/growth & development, Humans, Hydrolysis, Molecular Sequence Data, Molecular Weight, Proteolysis/drug effects, Sequence Alignment, Sequence Analysis, Protein, Serine Proteases/chemistry/*metabolism, Substrate Specificity/drug effects, Time Factors, Tosyl Compounds/pharmacology, Type V Secretion Systems/chemistry/*metabolism | Metabolism |
| Pathogenicity | 25384405 | Essential oils and isolated compounds from Lippia alba leaves and flowers: antimicrobial activity and osteoclast apoptosis. | Juiz PJ, Lucchese AM, Gambari R, Piva R, Penolazzi L, Di Ciano M, Uetanabaro AP, Silva F, Avila-Campos MJ | Int J Mol Med | 10.3892/ijmm.2014.1995 | 2014 | Anti-Infective Agents/chemistry/pharmacology, Apoptosis/drug effects, Cells, Cultured, Flowers/*chemistry, Humans, Lippia/*chemistry, Oils, Volatile/chemistry/*pharmacology, Osteoclasts/drug effects, Plant Extracts/chemistry/*pharmacology, Plant Leaves/*chemistry | |
| Pathogenicity | 26347298 | Identification of an antibacterial protein by functional screening of a human oral metagenomic library. | Arivaradarajan P, Warburton PJ, Paramasamy G, Nair SP, Allan E, Mullany P | FEMS Microbiol Lett | 10.1093/femsle/fnv142 | 2015 | Aldehyde Oxidoreductases/genetics, Amino Acid Sequence, Anti-Bacterial Agents/*chemistry/isolation & purification/pharmacology, Bacillus subtilis/drug effects, Bacteria/drug effects, Bacterial Proteins/*chemistry/isolation & purification/*pharmacology, Chromosomes, Artificial, Bacterial, Cloning, Molecular, Dental Plaque/*microbiology, Escherichia coli/genetics, Escherichia coli K12/drug effects, Genetic Vectors, Genomic Library, Humans, Lactobacillus casei/drug effects, *Metagenome, Molecular Sequence Data, Mutagenesis, Neisseria/*chemistry, Plasmids, Pseudomonas aeruginosa/drug effects, Saliva/*microbiology, Sequence Analysis, DNA, Staphylococcus aureus/drug effects, Staphylococcus epidermidis/drug effects | Enzymology |
| Biotechnology | 26538799 | The Effect of Bamboo Leaf Extract Solution and Sodium Copper Chlorophyllin Solution on Growth and Volatile Sulfur Compounds Production of Oral Malodor Associated Some Anaerobic Periodontal Bacteria. | Majbauddin A, Kodani I, Ryoke K | Yonago Acta Med | 2015 | |||
| Pathogenicity | 26923748 | Morphological and functional adaptations of Fusobacterium nucleatum exposed to human neutrophil Peptide-1. | Musrati AA, Fteita D, Paranko J, Kononen E, Gursoy UK | Anaerobe | 10.1016/j.anaerobe.2016.02.008 | 2016 | *Adaptation, Physiological, Bacterial Adhesion, Biofilms/*drug effects/growth & development, Cell Membrane/*drug effects/metabolism/ultrastructure, Cell Membrane Permeability/drug effects, Cytoplasmic Granules/drug effects/metabolism/ultrastructure, Dose-Response Relationship, Drug, Fusobacterium Infections/microbiology, Fusobacterium nucleatum/*drug effects/isolation & purification/metabolism/ultrastructure, Humans, Microscopy, Electron, Transmission, Neutrophils/metabolism, Plankton/*drug effects/metabolism/ultrastructure, Recombinant Proteins/biosynthesis/pharmacology, alpha-Defensins/biosynthesis/*pharmacology | Metabolism |
| Metabolism | 26930710 | FAD-I, a Fusobacterium nucleatum Cell Wall-Associated Diacylated Lipoprotein That Mediates Human Beta Defensin 2 Induction through Toll-Like Receptor-1/2 (TLR-1/2) and TLR-2/6. | Bhattacharyya S, Ghosh SK, Shokeen B, Eapan B, Lux R, Kiselar J, Nithianantham S, Young A, Pandiyan P, McCormick TS, Weinberg A | Infect Immun | 10.1128/IAI.01311-15 | 2016 | Amino Acid Substitution, Anti-Infective Agents/metabolism, Bacterial Proteins/genetics/immunology/*metabolism, Cells, Cultured, Cysteine/genetics/metabolism, Diglycerides/metabolism, Epithelial Cells/immunology/microbiology, Escherichia coli/genetics/metabolism, Fusobacterium nucleatum/*immunology, Humans, Protein Biosynthesis, Protein Multimerization, Protein Processing, Post-Translational, RNA, Messenger/biosynthesis, Recombinant Proteins/genetics/immunology/metabolism, Toll-Like Receptor 1/*metabolism, Toll-Like Receptor 2/*metabolism, Toll-Like Receptor 6/*metabolism, Transcription, Genetic, Transcriptional Activation, beta-Defensins/*biosynthesis | Pathogenicity |
| 27032997 | A dual-species microbial model for studying the dynamics between oral streptococci and periodontal pathogens during biofilm development on titanium surfaces by flow cytometry. | Manti A, Ciandrini E, Campana R, Dominici S, Ciacci C, Federici S, Sisti D, Rocchi MB, Papa S, Baffone W | Res Microbiol | 10.1016/j.resmic.2016.03.004 | 2016 | Biofilms/*growth & development, Enzyme-Linked Immunosorbent Assay, Flow Cytometry, Fusobacterium nucleatum/growth & development/*physiology, Gentian Violet/analysis, *Microbial Interactions, Mouth/*microbiology, Porphyromonas gingivalis/growth & development/*physiology, Staining and Labeling, Streptococcus/growth & development/*physiology, *Titanium | ||
| Enzymology | 27118478 | Copaifera reticulata oleoresin: Chemical characterization and antibacterial properties against oral pathogens. | Bardaji DK, da Silva JJ, Bianchi TC, de Souza Eugenio D, de Oliveira PF, Leandro LF, Rogez HL, Venezianni RC, Ambrosio SR, Tavares DC, Bastos JK, Martins CH | Anaerobe | 10.1016/j.anaerobe.2016.04.017 | 2016 | Anti-Bacterial Agents/chemistry/isolation & purification/*pharmacology, Bridged Bicyclo Compounds/isolation & purification, Cell Line, Cell Survival/drug effects, Dental Caries/microbiology, Fabaceae/*chemistry, Fibroblasts/cytology/drug effects, Humans, Lactobacillus casei/drug effects/growth & development/isolation & purification, Microbial Sensitivity Tests, Monocyclic Sesquiterpenes, Periodontitis/microbiology, Plant Extracts/chemistry/isolation & purification/*pharmacology, Porphyromonas gingivalis/*drug effects/growth & development/isolation & purification, Prevotella nigrescens/*drug effects/growth & development/isolation & purification, Sesquiterpenes/isolation & purification, Streptococcus mutans/drug effects/growth & development/isolation & purification, Streptococcus salivarius/drug effects/growth & development/isolation & purification, Terpenes/isolation & purification | Phylogeny |
| Metabolism | 27613803 | Discovery and characterization of de novo sialic acid biosynthesis in the phylum Fusobacterium. | Lewis AL, Robinson LS, Agarwal K, Lewis WG | Glycobiology | 10.1093/glycob/cww068 | 2016 | Chromatography, High Pressure Liquid, Fusobacterium/*metabolism, Mass Spectrometry, N-Acetylneuraminic Acid/*biosynthesis/chemistry | |
| Phylogeny | 27722787 | Bacterial invasion into radicular dentine-an in vitro study. | Stauffacher S, Lussi A, Nietzsche S, Neuhaus KW, Eick S | Clin Oral Investig | 10.1007/s00784-016-1960-7 | 2016 | Actinomyces/isolation & purification, Bacterial Load, Coculture Techniques, Dental Pulp Cavity/*microbiology, Dentin/*microbiology, Fusobacterium nucleatum/isolation & purification, Humans, In Vitro Techniques, Microscopy, Electron, Scanning, Porphyromonas gingivalis/isolation & purification, Prevotella intermedia/isolation & purification, Species Specificity, Streptococcus gordonii/isolation & purification, Streptococcus sanguis/isolation & purification | Enzymology |
| Pathogenicity | 27762731 | Strain-Specific Impact of Fusobacterium nucleatum on Neutrophil Function. | Kurgan S, Kansal S, Nguyen D, Stephens D, Koroneos Y, Hasturk H, Van Dyke TE, Kantarci A | J Periodontol | 10.1902/jop.2016.160212 | 2016 | Apoptosis, Biofilms, Cell Differentiation, Cell Line, Cells, Cultured, Cytokines/metabolism, Flow Cytometry, Fusobacterium nucleatum/*physiology, Host-Pathogen Interactions, Humans, Neutrophils/metabolism/*physiology, Phagocytosis/*physiology, Real-Time Polymerase Chain Reaction | Metabolism |
| Proteome | 28154519 | Mining the Proteome of Fusobacterium nucleatum subsp. nucleatum ATCC 25586 for Potential Therapeutics Discovery: An In Silico Approach. | Habib AM, Islam MS, Sohel M, Mazumder MH, Sikder MO, Shahik SM | Genomics Inform | 10.5808/GI.2016.14.4.255 | 2016 | ||
| Enzymology | 29021252 | A chemical and biological toolbox for Type Vd secretion: Characterization of the phospholipase A1 autotransporter FplA from Fusobacterium nucleatum. | Casasanta MA, Yoo CC, Smith HB, Duncan AJ, Cochrane K, Varano AC, Allen-Vercoe E, Slade DJ | J Biol Chem | 10.1074/jbc.M117.819144 | 2017 | Bacterial Proteins, Fusobacterium nucleatum/*enzymology/pathogenicity, Membrane Proteins, Phosphatidylinositols, Phospholipases A1/*chemistry/metabolism/physiology, Type V Secretion Systems/*chemistry, Virulence | Metabolism |
| Metabolism | 29343611 | Structural insights into the catalytic mechanism of cysteine (hydroxyl) lyase from the hydrogen sulfide-producing oral pathogen, Fusobacterium nucleatum. | Kezuka Y, Ishida T, Yoshida Y, Nonaka T | Biochem J | 10.1042/BCJ20170838 | 2018 | Catalysis, Catalytic Domain, Crystallography, X-Ray, Cysteine/*chemistry/metabolism, Cysteine Synthase/*chemistry/genetics/metabolism, Fusobacterium nucleatum/*enzymology/pathogenicity, Humans, Hydrogen Sulfide/chemistry/metabolism, Hydroxyl Radical/chemistry, Kinetics, Models, Molecular, *Protein Conformation, Schiff Bases/chemistry | Enzymology |
| Cultivation | 29364345 | Two mechanisms of oral malodor inhibition by zinc ions. | Suzuki N, Nakano Y, Watanabe T, Yoneda M, Hirofuji T, Hanioka T | J Appl Oral Sci | 10.1590/1678-7757-2017-0161 | 2018 | Acetates/chemistry, Anti-Bacterial Agents/chemistry/*pharmacology, Bacteria/drug effects/growth & development, Chlorides/chemistry, Culture Media, Halitosis/*drug therapy/microbiology, Hydrogen Sulfide/analysis/*antagonists & inhibitors/chemistry/metabolism, Microbial Sensitivity Tests, Reproducibility of Results, Statistics, Nonparametric, Time Factors, Volatilization, Zinc/chemistry/*pharmacology | Pathogenicity |
| Genetics | 29976645 | Fusobacterium Genomics Using MinION and Illumina Sequencing Enables Genome Completion and Correction. | Todd SM, Settlage RE, Lahmers KK, Slade DJ | mSphere | 10.1128/mSphere.00269-18 | 2018 | Computational Biology/*methods, Fusobacterium nucleatum/*genetics, *Genome, Bacterial, Sequence Analysis, DNA/*methods, Whole Genome Sequencing/*methods | Transcriptome |
| 30356383 | Antimicrobial Activity of Piper marginatum Jacq and Ilex guayusa Loes on Microorganisms Associated with Periodontal Disease. | Gamboa F, Munoz CC, Numpaque G, Sequeda-Castaneda LG, Gutierrez SJ, Tellez N | Int J Microbiol | 10.1155/2018/4147383 | 2018 | |||
| Phylogeny | 31501282 | Utilizing Whole Fusobacterium Genomes To Identify, Correct, and Characterize Potential Virulence Protein Families. | Umana A, Sanders BE, Yoo CC, Casasanta MA, Udayasuryan B, Verbridge SS, Slade DJ | J Bacteriol | 10.1128/JB.00273-19 | 2019 | Adhesins, Bacterial/classification/*genetics/metabolism, Amino Acid Sequence, Bacterial Adhesion, Cell Line, Computational Biology/methods, Epithelial Cells/microbiology/pathology, Fusobacterium/classification/*genetics/metabolism/*pathogenicity, Fusobacterium Infections/microbiology/pathology, Gene Expression, *Genome, Bacterial, Gingiva/microbiology/pathology, HCT116 Cells, Humans, Phylogeny, Sequence Alignment, Sequence Homology, Amino Acid, Type V Secretion Systems/classification/*genetics/metabolism, Virulence, Virulence Factors/classification/*genetics/metabolism | Metabolism |
| 32259029 | Pleural fluid penetration of moxifloxacin and doripenem: An experimental model of empyema. | Calik M, Calik SG, Dagli M, Kesli R, Esme H | North Clin Istanb | 10.14744/nci.2019.05902 | 2019 | |||
| Metabolism | 32271108 | Protocol of proceedings with Fusobacterium nucleatum and optimization of ABTS method for detection of reactive oxygen species. | Kedziora A, Lesiow MK, Krupa K, Korzeniowska-Kowal A, Adamski R, Komarnicka UK, Stokowa-Soltys K, Bugla-Ploskonska G, Jezowska-Bojczuk M | Future Microbiol | 10.2217/fmb-2019-0010 | 2020 | Benzothiazoles/chemistry, Copper/pharmacology, Fusobacterium nucleatum/*chemistry/drug effects/*metabolism, Hydrogen Peroxide/pharmacology, Reactive Oxygen Species/*analysis/*metabolism, Spectrophotometry/*methods, Sulfonic Acids/chemistry | Pathogenicity |
| Pathogenicity | 32416351 | Thymoquinone inhibits biofilm formation and virulence properties of periodontal bacteria. | Tantivitayakul P, Kaypetch R, Muadchiengka T | Arch Oral Biol | 10.1016/j.archoralbio.2020.104744 | 2020 | *Benzoquinones/pharmacology, Biofilms, *Fusobacterium nucleatum/drug effects, *Porphyromonas gingivalis/drug effects, Virulence | |
| Pathogenicity | 32549271 | New Pyrimidinone-Fused 1,4-Naphthoquinone Derivatives Inhibit the Growth of Drug Resistant Oral Bacteria. | Kim K, Kim D, Lee H, Lee TH, Kim KY, Kim H | Biomedicines | 10.3390/biomedicines8060160 | 2020 | ||
| 33088065 | Comparative evaluation of apical bacterial extrusion following root canal instrumentation using different endodontic file systems: An in vitro study. | Vankayala B, Anantula K, Saladi H, Gudugunta L, Basavarajaiah JM, Yadav SS | J Conserv Dent | 10.4103/JCD.JCD_221_19 | 2020 | |||
| Pathogenicity | 34259502 | Disruption of Metallostasis in the Anaerobic Human Pathogen Fusobacterium nucleatum by the Zinc Ionophore PBT2. | Van Zuylen EM, Ferguson SA, Hughes A, Rennison D, Brimble MA, Cook GM | ACS Infect Dis | 10.1021/acsinfecdis.0c00887 | 2021 | Anaerobiosis, Biofilms, *Fusobacterium nucleatum, Humans, Ionophores, *Zinc | |
| Transcriptome | 35085920 | Transcriptome analysis of Fusobacterium nucleatum reveals differential gene expression patterns in the biofilm versus planktonic cells. | Zhao T, Chen J, Liu S, Yang J, Wu J, Miao L, Sun W | Biochem Biophys Res Commun | 10.1016/j.bbrc.2021.11.075 | 2022 | Bacterial Proteins/genetics/*metabolism, Biofilms/*growth & development, Fusobacterium nucleatum/genetics/*metabolism, Gene Expression Profiling, Gene Expression Regulation, Bacterial, Humans, Plankton/genetics/growth & development/*metabolism, *Transcriptome, Virulence | Metabolism |
| Metabolism | 35359716 | Fusobacterium nucleatum Accelerates Atherosclerosis via Macrophage-Driven Aberrant Proinflammatory Response and Lipid Metabolism. | Zhou J, Liu L, Wu P, Zhao L, Wu Y | Front Microbiol | 10.3389/fmicb.2022.798685 | 2022 | Pathogenicity | |
| 35505575 | A murine periodontitis model using coaggregation between human pathogens and a predominant mouse oral commensal bacterium. | Liu M, Choi Y | J Periodontal Implant Sci | 10.5051/jpis.2104360218 | 2022 | |||
| 35618163 | Chalcones with potential antibacterial and antibiofilm activities against periodontopathogenic bacteria. | Satokata AAC, Souza JH, Silva LLO, Santiago MB, Ramos SB, Assis LR, Theodoro RDS, Oliveira LRE, Regasini LO, Martins CHG | Anaerobe | 10.1016/j.anaerobe.2022.102588 | 2022 |
Reference
| @id | authors | catalogue | doi/url | title | journal | pubmed |
|---|---|---|---|---|---|---|
| 6013 | Curators of the DSMZ | Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSM 15643) | https://www.dsmz.de/collection/catalogue/details/culture/DSM-15643 | |||
| 20215 | Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M. | 10.1099/ijsem.0.004332 | List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ | |||
| 20218 | Verslyppe, B., De Smet, W., De Baets, B., De Vos, P., Dawyndt P. | 10.1016/j.syapm.2013.11.002 | StrainInfo introduces electronic passports for microorganisms. | Syst Appl Microbiol. 37: 42-50 2014 | 24321274 | |
| 35308 | Curators of the CIP | https://brclims.pasteur.fr/brcWeb/souche/detail/1/12672 | ||||
| 65615 | Curators of the CCUG | Culture Collection University of Gothenburg (CCUG) (CCUG 32989) | https://www.ccug.se/strain?id=32989 | |||
| 66792 | Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann | https://diaspora-project.de/progress.html#genomes | Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) | |||
| 67770 | Curators of the JCM | https://jcm.brc.riken.jp/en/ | ||||
| 68371 | Automatically annotated from API 50CH acid | |||||
| 68380 | Automatically annotated from API rID32A | |||||
| 68382 | Automatically annotated from API zym | |||||
| 69479 | João F Matias Rodrigues, Janko Tackmann,Gregor Rot, Thomas SB Schmidt, Lukas Malfertheiner, Mihai Danaila,Marija Dmitrijeva, Daniela Gaio, Nicolas Näpflin and Christian von Mering. University of Zurich. | https://microbeatlas.org/ | MicrobeAtlas 1.0 beta | |||
| 69480 | Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann | https://diaspora-project.de/progress.html#genomes | Predictions based on genome sequence made in the Diaspora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) | |||
| 75244 | Reimer, L.C., Lissin, A.,Schober, I., Witte,J.F., Podstawka, A., Lüken, H., Bunk, B.,Overmann, J. | 10.60712/SI-ID92417.1 | StrainInfo: A central database for resolving microbial strain identifiers | |||
| 121367 | Curators of the CIP | Collection of Institut Pasteur (CIP 101130) | https://catalogue-crbip.pasteur.fr/fiche_catalogue.xhtml?crbip=CIP%20101130 |