Fusobacterium nucleatum subsp. nucleatum 1612A is an anaerobe, Gram-negative, rod-shaped bacterium that was isolated from cervico-facial lesion.
Gram-negative rod-shaped anaerobe genome sequence 16S sequence Bacteria
SI-ID 92417
| @ref 20215 |
|
Last LPSN update
2026-02-09 11:19:02 |
| Domain Bacteria |
| Phylum Fusobacteriota |
| Class Fusobacteriia |
| Order Fusobacteriales |
| Family Fusobacteriaceae |
| Genus Fusobacterium |
| Species Fusobacterium nucleatum subsp. nucleatum |
| Full scientific name Fusobacterium nucleatum subsp. nucleatum (Knorr 1922) Dzink et al. 1990 |
| BacDive ID | Other strains from Fusobacterium nucleatum subsp. nucleatum (1) | Type strain |
|---|---|---|
| 165390 | F. nucleatum subsp. nucleatum JCM 6328 |
| @ref | Name | Growth | Medium link | Composition | |
|---|---|---|---|---|---|
| 6013 | COLUMBIA BLOOD MEDIUM (DSMZ Medium 693) | Medium recipe at MediaDive  | Name: COLUMBIA BLOOD MEDIUM (DSMZ Medium 693) Composition: Defibrinated sheep blood 50.0 g/l Columbia agar base | ||
| 6013 | PYG MEDIUM (MODIFIED) (DSMZ Medium 104) | Medium recipe at MediaDive | Name: PYG MEDIUM (modified) (DSMZ Medium 104) Composition: Yeast extract 10.0 g/l Peptone 5.0 g/l Trypticase peptone 5.0 g/l Beef extract 5.0 g/l Glucose 5.0 g/l L-Cysteine HCl x H2O 0.5 g/l NaHCO3 0.4 g/l NaCl 0.08 g/l K2HPO4 0.04 g/l KH2PO4 0.04 g/l MgSO4 x 7 H2O 0.02 g/l CaCl2 x 2 H2O 0.01 g/l Hemin 0.005 g/l Ethanol 0.0038 g/l Resazurin 0.001 g/l Tween 80 Vitamin K1 NaOH Distilled water | ||
| 35308 | MEDIUM 20 - for Anaerobic bacteria | Agar (15.000 g);Glucose (5.000 g);Yeast extract (20.000 g);Tryptone (30.000 g);Cysteine hydrochloride (0.500 g);distilled water (1000.000 ml);Hemin solution -M00149 (25.000 ml) | |||
| 121367 | CIP Medium 45 | Medium recipe at CIP | |||
| 121367 | CIP Medium 20 | Medium recipe at CIP |
| @ref | Chebi-ID | Metabolite | Utilization activity | Kind of utilization tested | |
|---|---|---|---|---|---|
| 68371 | 27613 ChEBI | amygdalin | - | builds acid from | from API 50CH acid |
| 68371 | 18305 ChEBI | arbutin | - | builds acid from | from API 50CH acid |
| 68380 | 29016 ChEBI | arginine | - | hydrolysis | from API rID32A |
| 121367 | 17057 ChEBI | cellobiose | - | degradation | |
| 68371 | 17057 ChEBI | cellobiose | - | builds acid from | from API 50CH acid |
| 121367 | 17108 ChEBI | D-arabinose | - | degradation | |
| 68371 | 17108 ChEBI | D-arabinose | - | builds acid from | from API 50CH acid |
| 68371 | 18333 ChEBI | D-arabitol | - | builds acid from | from API 50CH acid |
| 121367 | 15824 ChEBI | D-fructose | - | degradation | |
| 68371 | 15824 ChEBI | D-fructose | - | builds acid from | from API 50CH acid |
| 68371 | 28847 ChEBI | D-fucose | - | builds acid from | from API 50CH acid |
| 68371 | 12936 ChEBI | D-galactose | - | builds acid from | from API 50CH acid |
| 121367 | 17634 ChEBI | D-glucose | - | degradation | |
| 68371 | 17634 ChEBI | D-glucose | - | builds acid from | from API 50CH acid |
| 68371 | 62318 ChEBI | D-lyxose | - | builds acid from | from API 50CH acid |
| 68371 | 16899 ChEBI | D-mannitol | - | builds acid from | from API 50CH acid |
| 68380 | 16024 ChEBI | D-mannose | - | fermentation | from API rID32A |
| 68371 | 16024 ChEBI | D-mannose | - | builds acid from | from API 50CH acid |
| 68371 | 16988 ChEBI | D-ribose | - | builds acid from | from API 50CH acid |
| 68371 | 17924 ChEBI | D-sorbitol | - | builds acid from | from API 50CH acid |
| 68371 | 16443 ChEBI | D-tagatose | - | builds acid from | from API 50CH acid |
| 121367 | 65327 ChEBI | D-xylose | - | degradation | |
| 68371 | 65327 ChEBI | D-xylose | - | builds acid from | from API 50CH acid |
| 68371 | 17113 ChEBI | erythritol | - | builds acid from | from API 50CH acid |
| 121367 | 4853 ChEBI | esculin | - | hydrolysis | |
| 68371 | 4853 ChEBI | esculin | - | builds acid from | from API 50CH acid |
| 68371 | 16813 ChEBI | galactitol | - | builds acid from | from API 50CH acid |
| 68371 | 28066 ChEBI | gentiobiose | - | builds acid from | from API 50CH acid |
| 68371 | 24265 ChEBI | gluconate | - | builds acid from | from API 50CH acid |
| 68371 | 17754 ChEBI | glycerol | - | builds acid from | from API 50CH acid |
| 68371 | 28087 ChEBI | glycogen | - | builds acid from | from API 50CH acid |
| 68371 | 15443 ChEBI | inulin | - | builds acid from | from API 50CH acid |
| 68371 | 30849 ChEBI | L-arabinose | - | builds acid from | from API 50CH acid |
| 68371 | 18403 ChEBI | L-arabitol | - | builds acid from | from API 50CH acid |
| 68371 | 18287 ChEBI | L-fucose | - | builds acid from | from API 50CH acid |
| 68380 | 29985 ChEBI | L-glutamate | - | degradation | from API rID32A |
| 68371 | 62345 ChEBI | L-rhamnose | - | builds acid from | from API 50CH acid |
| 68371 | 17266 ChEBI | L-sorbose | - | builds acid from | from API 50CH acid |
| 68371 | 65328 ChEBI | L-xylose | - | builds acid from | from API 50CH acid |
| 121367 | 17716 ChEBI | lactose | - | degradation | |
| 68371 | 17716 ChEBI | lactose | - | builds acid from | from API 50CH acid |
| 121367 | 17306 ChEBI | maltose | - | degradation | |
| 68371 | 17306 ChEBI | maltose | - | builds acid from | from API 50CH acid |
| 68371 | 6731 ChEBI | melezitose | - | builds acid from | from API 50CH acid |
| 68371 | 28053 ChEBI | melibiose | - | builds acid from | from API 50CH acid |
| 68371 | 320061 ChEBI | methyl alpha-D-glucopyranoside | - | builds acid from | from API 50CH acid |
| 68371 | 43943 ChEBI | methyl alpha-D-mannoside | - | builds acid from | from API 50CH acid |
| 68371 | 74863 ChEBI | methyl beta-D-xylopyranoside | - | builds acid from | from API 50CH acid |
| 68371 | 17268 ChEBI | myo-inositol | - | builds acid from | from API 50CH acid |
| 68371 | 59640 ChEBI | N-acetylglucosamine | - | builds acid from | from API 50CH acid |
| 121367 | 17632 ChEBI | nitrate | - | reduction | |
| 121367 | 17632 ChEBI | nitrate | + | respiration | |
| 121367 | 16301 ChEBI | nitrite | - | reduction | |
| 68371 | Potassium 2-ketogluconate | - | builds acid from | from API 50CH acid | |
| 68371 | Potassium 5-ketogluconate | - | builds acid from | from API 50CH acid | |
| 68371 | 16634 ChEBI | raffinose | - | builds acid from | from API 50CH acid |
| 68380 | 16634 ChEBI | raffinose | - | fermentation | from API rID32A |
| 68371 | 15963 ChEBI | ribitol | - | builds acid from | from API 50CH acid |
| 121367 | 17814 ChEBI | salicin | - | degradation | |
| 68371 | 17814 ChEBI | salicin | - | builds acid from | from API 50CH acid |
| 68371 | 28017 ChEBI | starch | - | builds acid from | from API 50CH acid |
| 121367 | 17992 ChEBI | sucrose | - | degradation | |
| 68371 | 17992 ChEBI | sucrose | - | builds acid from | from API 50CH acid |
| 68371 | 27082 ChEBI | trehalose | - | builds acid from | from API 50CH acid |
| 68371 | 32528 ChEBI | turanose | - | builds acid from | from API 50CH acid |
| 68380 | 16199 ChEBI | urea | - | hydrolysis | from API rID32A |
| 68371 | 17151 ChEBI | xylitol | - | builds acid from | from API 50CH acid |
| @ref | Value | Activity | Ec | |
|---|---|---|---|---|
| 68382 | acid phosphatase | + | 3.1.3.2 | from API zym |
| 68380 | alanine arylamidase | - | 3.4.11.2 | from API rID32A |
| 121367 | alcohol dehydrogenase | - | 1.1.1.1 | |
| 68382 | alkaline phosphatase | - | 3.1.3.1 | from API zym |
| 68380 | alkaline phosphatase | - | 3.1.3.1 | from API rID32A |
| 68380 | alpha-arabinosidase | - | 3.2.1.55 | from API rID32A |
| 68382 | alpha-chymotrypsin | - | 3.4.21.1 | from API zym |
| 68382 | alpha-fucosidase | - | 3.2.1.51 | from API zym |
| 68380 | alpha-fucosidase | - | 3.2.1.51 | from API rID32A |
| 68382 | alpha-galactosidase | - | 3.2.1.22 | from API zym |
| 68380 | alpha-galactosidase | - | 3.2.1.22 | from API rID32A |
| 68382 | alpha-glucosidase | + | 3.2.1.20 | from API zym |
| 68380 | alpha-glucosidase | - | 3.2.1.20 | from API rID32A |
| 68382 | alpha-mannosidase | - | 3.2.1.24 | from API zym |
| 121367 | amylase | - | ||
| 68380 | arginine dihydrolase | - | 3.5.3.6 | from API rID32A |
| 68382 | beta-galactosidase | - | 3.2.1.23 | from API zym |
| 121367 | beta-galactosidase | + | 3.2.1.23 | |
| 68380 | beta-galactosidase | - | 3.2.1.23 | from API rID32A |
| 68380 | beta-Galactosidase 6-phosphate | - | from API rID32A | |
| 68382 | beta-glucosidase | - | 3.2.1.21 | from API zym |
| 68380 | beta-glucosidase | - | 3.2.1.21 | from API rID32A |
| 68382 | beta-glucuronidase | - | 3.2.1.31 | from API zym |
| 68380 | beta-glucuronidase | - | 3.2.1.31 | from API rID32A |
| 121367 | caseinase | - | 3.4.21.50 | |
| 121367 | catalase | - | 1.11.1.6 | |
| 68382 | cystine arylamidase | - | 3.4.11.3 | from API zym |
| 121367 | DNase | - | ||
| 68382 | esterase (C 4) | + | from API zym | |
| 68382 | esterase lipase (C 8) | + | from API zym | |
| 121367 | gelatinase | - | ||
| 68380 | glutamate decarboxylase | - | 4.1.1.15 | from API rID32A |
| 68380 | glutamyl-glutamate arylamidase | - | from API rID32A | |
| 68380 | glycin arylamidase | - | from API rID32A | |
| 68380 | histidine arylamidase | - | from API rID32A | |
| 68380 | L-arginine arylamidase | - | from API rID32A | |
| 121367 | lecithinase | + | ||
| 68382 | leucine arylamidase | + | 3.4.11.1 | from API zym |
| 68380 | leucine arylamidase | - | 3.4.11.1 | from API rID32A |
| 68380 | leucyl glycin arylamidase | - | 3.4.11.1 | from API rID32A |
| 121367 | lipase | - | ||
| 68382 | lipase (C 14) | - | from API zym | |
| 121367 | lysine decarboxylase | - | 4.1.1.18 | |
| 68382 | N-acetyl-beta-glucosaminidase | - | 3.2.1.52 | from API zym |
| 68380 | N-acetyl-beta-glucosaminidase | - | 3.2.1.52 | from API rID32A |
| 68382 | naphthol-AS-BI-phosphohydrolase | + | from API zym | |
| 121367 | ornithine decarboxylase | - | 4.1.1.17 | |
| 121367 | oxidase | - | ||
| 68380 | phenylalanine arylamidase | - | from API rID32A | |
| 68380 | proline-arylamidase | - | 3.4.11.5 | from API rID32A |
| 121367 | protease | + | ||
| 68380 | pyrrolidonyl arylamidase | - | 3.4.19.3 | from API rID32A |
| 68380 | serine arylamidase | - | from API rID32A | |
| 68382 | trypsin | - | 3.4.21.4 | from API zym |
| 121367 | tween esterase | - | ||
| 68380 | tyrosine arylamidase | - | from API rID32A | |
| 121367 | urease | - | 3.5.1.5 | |
| 68380 | urease | - | 3.5.1.5 | from API rID32A |
| 68382 | valine arylamidase | - | from API zym |
Metadata FA analysis  | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| @ref | 65615 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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| @ref | ControlQ | GLY | ERY | DARA | LARA | RIB | DXYL | LXYL | ADO | MDX | GAL | GLU | FRU | MNE | SBE | RHA | DUL | INO | MAN | SOR | MDM | MDG | NAG | AMY | ARB | ESC | SAL | CEL | MAL | LAC | MEL | SAC | TRE | INU | MLZ | RAF | AMD | GLYG | XLT | GEN | TUR | LYX | TAG | DFUC | LFUC | DARL | LARL | GNT | 2KG | 5KG | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 121367 | not determinedn.d. | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| @ref | URE | ADH (Arg) | alpha GAL | beta GAL | beta-Galactosidase 6-phosphatebeta GP | alpha GLU | beta GLU | alpha ARA | beta GUR | beta-N-Acetyl-beta-glucosaminidasebeta NAG | MNE | RAF | GDC | alpha FUC | Reduction of nitrateNIT | IND | PAL | L-arginine arylamidaseArgA | ProA | LGA | Phenylalanine arylamidasePheA | Leucine arylamidaseLeuA | PyrA | Tyrosine arylamidaseTyrA | Alanine arylamidaseAlaA | Glycin arylamidaseGlyA | Histidine arylamidaseHisA | Glutamyl-glutamate arylamidaseGGA | Serine arylamidaseSerA | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 6013 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | + | - | - | - | - | - | - | - | - | - | - | - | - | - | |
| 6013 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | + | - | - | - | - | - | - | - | - | - | - | - | - | - | - | |
| 6013 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | + | - | - | - | - | - | - | - | - | - | - | - | - | - | |
| 6013 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | + | - | - | - | - | - | - | - | - | - | - | - | - | - | |
| 6013 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | + | - | - | - | - | - | - | - | - | - | - | - | - | - | |
| 6013 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | + | - | - | - | - | - | - | - | - | - | - | - | - | - | |
| 6013 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | + | - | - | - | - | - | - | - | - | - | - | - | - | - | |
| 6013 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | + | - | - | - | - | - | - | - | - | - | - | - | - | - | |
| 6013 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | + | - | - | - | - | - | - | - | - | - | - | - | - | - | |
| 6013 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | + | - | - | - | - | - | - | - | - | - | - | - | - | - |
| Cat1 | Cat2 | Cat3 | |
|---|---|---|---|
| #Host Body-Site | #Oral cavity and airways | #Throat | |
| #Host Body-Site | #Other | #Wound |
Global distribution of 16S sequence GQ301038 (>99% sequence identity) for Fusobacterium nucleatum from Microbeatlas 
 Aquatic Samples |
188 |
 Soil Samples |
15 |
 Animal Samples |
3393 |
 Plant Samples |
16 |
| Total Samples | 3612 |
| @ref | Description | Assembly level | INSDC accession | BV-BRC accession | IMG accession | NCBI tax ID | Score | |
|---|---|---|---|---|---|---|---|---|
| 124043 | ASM3119179v1 assembly for Fusobacterium nucleatum LMG 13131 | complete | GCA_031191795   | 851.486  | 8116893199  | 851 | 99.3 | |
| 124043 | ASM301929v1 assembly for Fusobacterium nucleatum subsp. nucleatum ATCC 25586 | complete | GCA_003019295 | 76856.6 | 2849012876 | 190304 | 99.23 | |
| 124043 | Fn25586 assembly for Fusobacterium nucleatum subsp. nucleatum ATCC 25586 | complete | GCA_050920715 | 190304 | 98.57 | | ||
| 124043 | Fn3 assembly for Fusobacterium nucleatum subsp. nucleatum ATCC 25586 | complete | GCA_964642115 | 190304 | 97.68 | | ||
| 124043 | ASM3790034v1 assembly for Fusobacterium nucleatum subsp. nucleatum ATCC 25586 | complete | GCA_037900345 | 190304 | 97.36 | | ||
| 66792 | ASM732v1 assembly for Fusobacterium nucleatum subsp. nucleatum ATCC 25586 | complete | GCA_000007325 | 190304.8 | 637000117 | 190304 | 74.75 | |
| @ref | Description | Accession | Length | Database | NCBI tax ID | |
|---|---|---|---|---|---|---|
| 20218 | Fusobacterium nucleatum subsp. nucleatum gene for 16S ribosomal RNA, partial sequence, strain: JCM 8532 | AB573068 | 1481 |  | 190304 | |
| 20218 | Fusobacterium nucleatum subsp. nucleatum strain ATCC 25586 16S ribosomal RNA gene, partial sequence; internal transcribed spacer 1, complete sequence; and 23S ribosomal RNA gene, partial sequence | AF342829 | 745 | | 190304 | |
| 20218 | Fusobacterium nucleatum subsp. nucleatum 16S ribosomal RNA gene | AJ133496 | 1479 | | 190304 | |
| 20218 | Fusobacterium nucleatum subsp. nucleatum strain ATCC 25586 16S ribosomal RNA gene, partial sequence | GQ301038 | 1442 | | 190304 | |
| 20218 | Fusobacterium nucleatum subsp. nucleatum small subunit ribosomal RNA gene sequence | M58683 | 1522 | | 190304 | |
| 20218 | Fusobacterium nucleatum subsp. nucleatum small subunit ribosomal RNA | X55401 | 1331 | | 190304 | |
| Topic | Title | Authors | Journal | DOI | Year | |
|---|---|---|---|---|---|---|
| Identification of anaerobic bacterial strains by pyrolysis-gas chromatography-ion mobility spectrometry. | Kobelt T, Klose J, Mukherjee R, Lippmann M, Szafranski SP, Stiesch M, Zimmermann S. | Front Bioeng Biotechnol | 10.3389/fbioe.2025.1582565 | 2025 | | |
| The inhibitory effects of ginsenosides on periodontitis pathogenic bacteria. | Lei Q, Chen J, Yuan Y, Hu C, Lin Z, Yang S, Mayo KH, Zhou Y, Sun L, Song W. | Front Microbiol | 10.3389/fmicb.2025.1573969 | 2025 | | |
| Antibacterial potential of silver and zinc loaded plasma-electrolytic oxidation coatings for dental titanium implants. | Paiwand S, Schafer S, Kopp A, Beikler T, Fiedler I, Gosau M, Fuest S, Smeets R. | Int J Implant Dent | 10.1186/s40729-025-00595-w | 2025 | | |
| Influence of species composition and cultivation condition on peri-implant biofilm dysbiosis in vitro. | Heine N, Bittroff K, Szafranski SP, Duitscher M, Behrens W, Vollmer C, Mikolai C, Kommerein N, Debener N, Frings K, Heisterkamp A, Scheper T, Torres-Mapa ML, Bahnemann J, Stiesch M, Doll-Nikutta K. | Front Oral Health | 10.3389/froh.2025.1649419 | 2025 | | |
| Detection of Fusobacterium nucleatum in Patients with Colitis-Associated Colorectal Cancer. | Dregelies T, Haumaier F, Sterlacci W, Backert S, Vieth M. | Curr Microbiol | 10.1007/s00284-023-03398-7 | 2023 | | |
| Lactobacillus probiotic cell-free supernatants and vitamin D influence interleukin-6 production and mitigate oral periodontopathogens-induced cytotoxicity in FaDu cells. | Zanetta P, De Giorgis V, Barberis E, Manfredi M, Amoruso A, Pane M, Azzimonti B. | Front Microbiol | 10.3389/fmicb.2025.1578267 | 2025 | | |
| Optically accessible, 3D-printed flow chamber with integrated sensors for the monitoring of oral multispecies biofilm growth in vitro. | Debener N, Heine N, Legutko B, Denkena B, Prasanthan V, Frings K, Torres-Mapa ML, Heisterkamp A, Stiesch M, Doll-Nikutta K, Bahnemann J. | Front Bioeng Biotechnol | 10.3389/fbioe.2024.1483200 | 2024 | | |
| Growth Conditions Influence Lactobacillus Cell-Free Supernatant Impact on Viability, Biofilm Formation, and Co-Aggregation of the Oral Periodontopathogens Fusobacterium nucleatum and Porphyromonas gingivalis. | Zanetta P, Squarzanti DF, di Coste A, Amoruso A, Pane M, Azzimonti B. | Biomedicines | 10.3390/biomedicines11030859 | 2023 | | |
| Growth rate alterations of human colorectal cancer cells by 157 gut bacteria. | Taddese R, Garza DR, Ruiter LN, de Jonge MI, Belzer C, Aalvink S, Nagtegaal ID, Dutilh BE, Boleij A. | Gut Microbes | 10.1080/19490976.2020.1799733 | 2020 | | |
| Genetics | Application of shotgun metagenomics to smoked salmon experimentally spiked: Comparison between sequencing and microbiological data using different bioinformatic approaches. | Cesare A, Oliveri C, Lucchi A, Pasquali F, Manfreda G. | Ital J Food Saf | 10.4081/ijfs.2019.8462 | 2019 | |
| In Vitro Antibacterial Effectiveness of a Naturopathic Oral Care Product on Oral Pathogens. | Beyer A, Dalton M, Doll K, Winkel A, Stumpp NS, Stiesch M. | Oral Health Prev Dent | 10.3290/j.ohpd.a44938 | 2020 | | |
| Metabolism | Fusobacterium nucleatum Extracellular Vesicles Modulate Gut Epithelial Cell Innate Immunity via FomA and TLR2. | Martin-Gallausiaux C, Malabirade A, Habier J, Wilmes P. | Front Immunol | 10.3389/fimmu.2020.583644 | 2020 | |
| Marginal Adaptation and Microbial Leakage at Conometric Prosthetic Connections for Implant-Supported Single Crowns: An In Vitro Investigation. | Gehrke P, Hartjen P, Smeets R, Gosau M, Peters U, Beikler T, Fischer C, Stolzer C, Geis-Gerstorfer J, Weigl P, Schafer S. | Int J Mol Sci | 10.3390/ijms22020881 | 2021 | | |
| The presence of bacteria varies between colorectal adenocarcinomas, precursor lesions and non-malignant tissue. | Bundgaard-Nielsen C, Baandrup UT, Nielsen LP, Sorensen S. | BMC Cancer | 10.1186/s12885-019-5571-y | 2019 | | |
| Evaluation of microbiota associated with Herpesviruses in active sites of generalized aggressive periodontitis. | Passariello C, Gigola P, Testarelli L, Puttini M, Schippa S, Petti S. | Ann Stomatol (Roma) | 10.11138/ads/2017.8.2.071 | 2017 | | |
| Metabolism | SIMMER employs similarity algorithms to accurately identify human gut microbiome species and enzymes capable of known chemical transformations. | Bustion AE, Nayak RR, Agrawal A, Turnbaugh PJ, Pollard KS. | Elife | 10.7554/elife.82401 | 2023 | |
| Metabolism | Molecular and Low-Resolution Structural Characterization of the Na+-Translocating Glutaconyl-CoA Decarboxylase From Clostridium symbiosum. | Vitt S, Prinz S, Hellwig N, Morgner N, Ermler U, Buckel W. | Front Microbiol | 10.3389/fmicb.2020.00480 | 2020 | |
| Quantitative molecular detection of putative periodontal pathogens in clinically healthy and periodontally diseased subjects. | Gohler A, Hetzer A, Holtfreter B, Geisel MH, Schmidt CO, Steinmetz I, Kocher T. | PLoS One | 10.1371/journal.pone.0099244 | 2014 | | |
| Enzymology | Comprehensive Laboratory Evaluation of a Specific Lateral Flow Assay for the Presumptive Identification of Francisella tularensis in Suspicious White Powders and Aerosol Samples. | Pillai SP, DePalma L, Prentice KW, Ramage JG, Chapman C, Sarwar J, Parameswaran N, Petersen J, Yockey B, Young J, Singh A, Pillai CA, Manickam G, Thirunavkkarasu N, Avila JR, Sharma S, Morse SA, Venkateswaran K, Anderson K, Hodge DR. | Health Secur | 10.1089/hs.2019.0151 | 2020 | |
| Enzymology | Comprehensive Laboratory Evaluation of a Lateral Flow Assay for the Detection of Yersinia pestis. | Prentice KW, DePalma L, Ramage JG, Sarwar J, Parameswaran N, Petersen J, Yockey B, Young J, Joshi M, Thirunavvukarasu N, Singh A, Chapman C, Avila JR, Pillai CA, Manickam G, Sharma SK, Morse SA, Venkateswaran KV, Anderson K, Hodge DR, Pillai SP. | Health Secur | 10.1089/hs.2019.0094 | 2019 | |
| Development of an in vitro Model of Human Gut Microbiota for Screening the Reciprocal Interactions With Antibiotics, Drugs, and Xenobiotics. | El Houari A, Ecale F, Mercier A, Crapart S, Laparre J, Soulard B, Ramnath M, Berjeaud JM, Rodier MH, Crepin A. | Front Microbiol | 10.3389/fmicb.2022.828359 | 2022 | | |
| Adhesion of Porphyromonas gingivalis and Biofilm Formation on Different Types of Orthodontic Brackets. | Papaioannou W, Panagopoulos A, Koletsi-Kounari H, Kontou E, Makou M. | Int J Dent | 10.1155/2012/471380 | 2012 | | |
| Enzymology | Comprehensive Laboratory Evaluation of a Highly Specific Lateral Flow Assay for the Presumptive Identification of Bacillus anthracis Spores in Suspicious White Powders and Environmental Samples. | Ramage JG, Prentice KW, DePalma L, Venkateswaran KS, Chivukula S, Chapman C, Bell M, Datta S, Singh A, Hoffmaster A, Sarwar J, Parameswaran N, Joshi M, Thirunavkkarasu N, Krishnan V, Morse S, Avila JR, Sharma S, Estacio PL, Stanker L, Hodge DR, Pillai SP. | Health Secur | 10.1089/hs.2016.0041 | 2016 | |
| Metabolism | Methotrexate impacts conserved pathways in diverse human gut bacteria leading to decreased host immune activation. | Nayak RR, Alexander M, Deshpande I, Stapleton-Gray K, Rimal B, Patterson AD, Ubeda C, Scher JU, Turnbaugh PJ. | Cell Host Microbe | 10.1016/j.chom.2020.12.008 | 2021 | |
| Ferulic acid suppresses Porphyromonas gingivalis biofilm formation via the inhibition of autoinducer-2 production and receptor activity. | Ando D, Lwin HY, Aoki-Nonaka Y, Matsugishi-Nasu A, Minato Y, Warita Y, Takahashi N, Tabeta K. | Arch Oral Biol | 10.1016/j.archoralbio.2025.106365 | 2025 | | |
| Antibody responses to 11 Fusobacterium proteins and colorectal cancer-specific and overall survival in the EPIC cohort. | Michaud DS, Platz EA, Garrett WS, Waterboer T, Kaaks R, Pasanisi F, Abilleira E, Pala V, Milani L, Castilla J, Rodriguez Palacios D, Tumino R, Masala G, Farras M, Sanchez MJ, Papier K, Severi G, Tsilidis KK, Jenab M, Butt J, Hughes DJ. | Cancer Epidemiol Biomarkers Prev | 10.1158/1055-9965.epi-25-1084 | 2025 | | |
| The Relationship Between the Growth of Fusobacterium nucleatum ATCC 25586 in Glucose-Enriched Media and Protein Activity through Fourier Transform Infrared (FTIR). | Saputri D, Muhammad Alibasyah Z, Nuzulul Ismi S, Arfirosa A. | Rep Biochem Mol Biol | 10.61186/rbmb.13.3.310 | 2024 | | |
| Microbial Coaggregation in the Oral Cavity: Molecular Interactions and Current Insights. | Oogai Y, Tanaka Y, Nakata M. | Int J Mol Sci | 10.3390/ijms262110552 | 2025 | | |
| Oral Fusobacterium nucleatum resists the acidic pH of the stomach due to membrane erucic acid synthesized via enoyl-CoA hydratase-related protein FnFabM. | Li X, Zhang S, Sheng H, Zhen Y, Wu B, Li Z, Chen D, Zhou H. | J Oral Microbiol | 10.1080/20002297.2025.2453964 | 2025 | | |
| Genetics | Closed genome sequence of Fretibacterium fastidiosum, a potential contributor to periodontal disease. | Mori A, Kudoh M, Kuboniwa M, Ruckert-Reed C, Busche T, Eisenhut M, Fukusaki E, Brautigam A, Laker B. | Microbiol Resour Announc | 10.1128/mra.00004-25 | 2025 | |
| The Effect of Bovine Lactoferrin on Fusobacterium nucleatum: A Study on Its Antibacterial and Immunomodulatory Properties in Periodontitis Management. | Khatib HMA. | Cureus | 10.7759/cureus.90279 | 2025 | | |
| Impact of oral pathogens on inflammatory mediator expression in oral cells. | Hodar PS, Shah M, Fu Y, P Shah P, Haldia A, Agrawal A, Mehta M. | Bioinformation | 10.6026/973206300211506 | 2025 | | |
| The Relationship Between the Growth of Fusobacterium nucleatum ATCC 25586 in Glucose-Enriched Media and Protein Activity through Fourier Transform Infrared (FTIR) | Saputri D, Muhammad Alibasyah Z, Nuzulul Ismi S, Arfirosa A. | Rep Biochem Mol Biol | 2024 | | ||
| Antibiofilm potential of plant extracts: inhibiting oral microorganisms and Streptococcus mutans. | Bartels N, Argyropoulou A, Al-Ahmad A, Hellwig E, Skaltsounis AL, Wittmer A, Vach K, Karygianni L. | Front Dent Med | 10.3389/fdmed.2025.1535753 | 2025 | | |
| Antimicrobial Efficacy of Nano-Hydroxyapatite-Coated Implants Against Peri-Implantitis-Associated Bacteria. | Sharma N, Shukla J, Jain S, Vyas R, Verma T, Navlani B. | J Pharm Bioallied Sci | 10.4103/jpbs.jpbs_169_25 | 2025 | | |
| Limosilactobacillus reuteri-Fusobacterium nucleatum Interactions Modulate Biofilm Composition and Immunogenicity. | Yang L, Sriram G, Chew RJJ, Tan KS. | J Periodontal Res | 10.1111/jre.70021 | 2025 | | |
| Discovery, characterization, and structure of a cofactor-independent histidine racemase from the oral pathogen Fusobacterium nucleatum. | Lamer T, Chen P, Venter MJ, van Belkum MJ, Wijewardane A, Wu C, Lemieux MJ, Vederas JC. | J Biol Chem | 10.1016/j.jbc.2024.107896 | 2024 | | |
| Unleashing nature's defense: potent antimicrobial power of plant extracts against oral pathogens and Streptococcus mutans biofilms. | Hickl J, Argyropoulou A, Al-Ahmad A, Hellwig E, Skaltsounis AL, Wittmer A, Vach K, Karygianni L. | Front Oral Health | 10.3389/froh.2024.1469174 | 2024 | | |
| Fusobacterium lineage profiling facilitates the clarification of the associations between non-nucleatum Fusobacterium and colorectal cancer. | Wu Y, Ji G, Han D, Zhang Y, Zhu X, Li H, Li M, Gao Y, Xie R, Xu M, Lu L, Deng Z, Wei Q, Qin H, Bi D. | NPJ Biofilms Microbiomes | 10.1038/s41522-025-00826-3 | 2025 | | |
| Engineering Short Antimicrobial Peptides to Specifically Target Fusobacterium nucleatum in the Mixed Microbial Population. | Liu Z, Wang Y, Zhang C, Yang Y, Zhang J. | ACS Infect Dis | 10.1021/acsinfecdis.4c00387 | 2024 | | |
| Antimicrobial efficacy of blueM gel and calcium hydroxide against F. nucleatum and E. faecalis biofilm: an ex-vivo study. | Alharbi YR, Srivastava S, Alsalhi H, Almohimeed K, Alduraibi M, Nabil A. | Saudi Dent J | 10.1007/s44445-025-00042-x | 2025 | | |
| Fusobacterium nucleatum enhances oxaliplatin resistance in colon cancer by increasing PVT1 expression. | Gao K, Zhang J, Liu C, Yang Y, Wang J, Zhang J, Ma H, Wang F, Zhao L, Wang G. | J Transl Med | 10.1186/s12967-025-07226-3 | 2025 | | |
| Fusobacterium nucleatum increases CTGF expression through TLR2-YAP signaling axis in cancer-associated fibroblasts, thereby promoting colorectal cancer progression. | Wang H, Lin B, Wang Z, Yang J, Guo X, Li W, Li B, Shi S, Zhou Y, Han R, Wei Y, Liu Y. | Cancer Cell Int | 10.1186/s12935-025-04023-2 | 2025 | | |
| Dysbiosis modulates CD8+ tissue-resident memory cells through a mechanism requiring polyamine metabolism during HIV infection. | Jayaraman S, Mahalingam S, Lederman MM, Faddoul F, Paes da Silva A, Asaad R, Shriver LP, Bhaskaran N, Schneider E, Heine G, Taylor T, Horne S, Yoon A, Zhu Z, Zhang L, Burgener A, Lewin G, Pandiyan P. | iScience | 10.1016/j.isci.2025.113679 | 2025 | | |
| Fusobacterium nucleatum Infection Drives Glutathione Depletion in Gastric Cancer: Integrated Multi-Omics and Experimental Validation | Nie S, Gong Y, Wang A, Guo R, Chen X, Yuan Y. | Microorganisms | 2025 | | ||
| Benzyl isothiocyanate exhibits antibacterial and antibiofilm activity against Fusobacterium nucleatum while preserving viability of human bone marrow mesenchymal stem cells: an in vitro study. | Almobarak AA, Alqedairi A, Binrayes A, Lambarte RA, Niazy AA, Aljarbou F. | Front Cell Infect Microbiol | 10.3389/fcimb.2025.1683203 | 2025 | | |
| Comparison of oral and gut microbiome highlights role of oral bacteria in systemic inflammation in HIV | Fulcher J, Newman K, Pham B, Li F, Cho G, Elliott J, Tobin N, Shoptaw S, Gorbach P, Aldrovandi G. | bioRxiv | 2025 | | ||
| Phylogeny | The rise and evolving role of Fusobacterium nucleatum subspecies. | Wolf M, Steinberg T, Scholz KJ, Kruse A, Rezasoltani S, Conrads G, Al-Ahmad A, Cieplik F. | Curr Res Microb Sci | 10.1016/j.crmicr.2025.100414 | 2025 | |
| Fusobacterium nucleatum mechanism of action in alveolar bone destruction: Scoping review. | Idrus E, Harsono TS, Lestari W, Suniarti DF. | J Indian Soc Periodontol | 10.4103/jisp.jisp_269_23 | 2024 | | |
| In-Vitro Effect of Manuka Honey / Propolis Toothpastes on Bacteria and Biofilm Associated with Caries and Gingivitis. | Jungbauer G, Lechner R, Stahli A, Sculean A, Eick S. | Oral Health Prev Dent | 10.3290/j.ohpd.c_1910 | 2025 | | |
| Fusobacterium nucleatum Promotes the Growth and Metastasis of Colorectal Cancer by Activating E-Cadherin/Krüppel-Like Factor 4/Integrin alpha5 Signaling in a Calcium-Dependent Manner. | Yan X, Qu X, Wang J, Lu L, Wu W, Mao J, Li D, Wang Y, Wei Q, Liu J. | MedComm (2020) | 10.1002/mco2.70137 | 2025 | | |
| Evaluation of Cytotoxicity and Antimicrobial Activity of Experimental Composites Containing Chitosan-Silver Oxide Particles Against Two Main Pathogenic Bacteria in Periodontal Disease. | Nasrabadi N, Ramezanian N, Ghorbanian P, Forouzanfar A, Mohammadipour HS. | Protein Pept Lett | 10.2174/0109298665240242231016103321 | 2024 | | |
| Ethanolamine-induced assembly of microcompartments is required for Fusobacterium nucleatum virulence. | Franklin DS, Chen Y-W, Chen Y, Wittchen M, Agnew A, Luu A, Whitelegge JP, Zhou ZH, Tauch A, Das A, Ton-That H. | mBio | 10.1128/mbio.03405-24 | 2025 | | |
| Probing antibacterial drugs for Fusobacterium nucleatum subsp. nucleatum ATCC 25586 targeting UDP-N-acetylglucosamine 1-carboxyltransferase. | Saputri D, Mubarak Z, Mudatsir M, Setyawati I, Setiawan AG, Abrar M. | J Adv Pharm Technol Res | 10.4103/japtr.japtr_129_23 | 2023 | | |
| The Involvement of Oral Pathogenic Bacteria, Fusobacterium nucleatum Subspecies animalis in the Pathogenesis of Human Esophageal Adenocarcinoma | Kitano T, Okumura S, Matsumoto T, Tsunoda S, Nishigori T, Obama K, Hara E. | Gastro Hep Adv | 2025 | | ||
| Pathogenicity | Can Fusobacterium utilize nucleomodulins in the pathophysiology of CRC? | Anand S, Korgaonkar S, Bose C. | Front Cell Infect Microbiol | 10.3389/fcimb.2025.1644443 | 2025 | |
| Lavandula angustifolia Essential Oil Inhibits the Ability of Fusobacterium nucleatum to Produce Volatile Sulfide Compounds, a Key Components in Oral Malodor. | Rosner O, Livne S, Bsharat M, Dviker S, Jeffet U, Matalon S, Sterer N. | Molecules | 10.3390/molecules29132982 | 2024 | | |
| Phylogeny | Effects of oral gavage with periodontal pathogens and plaque biofilm on gut microbiota ecology and intestinal tissue architecture in mice: a mechanistic study. | Huang L, Ge S, Yang K, Duan L, Gao L, Li YZ, Yi YS. | Front Cell Infect Microbiol | 10.3389/fcimb.2025.1589055 | 2025 | |
| Pathogenicity | Investigating the Impact of Fusobacterium nucleatum on Oxidative Stress, Chemoresistance, and Inflammation in Inflammatory Bowel Disease and Colorectal Cancer: Rationale and Design of a Clinical Trial | Consolo P, Giorgi C, Crisafulli C, Fiorica F, Pinton P, Maurea N, Missiroli S, Quagliariello V, Mantoan B, Ottaiano A, Pellicano G, Orru G, Scano A, Cacciola I, Pollicino T, Di Mauro G, Berretta S, Bignucolo A, Toscano E, Ciappina G, Berretta M. | Int J Mol Sci | 2025 | | |
| Assessment of a Light-Curable Hydrogel to Be Used for Root Canal Obturation. | Bhandari S, Kuehne S, Camilleri J. | J Dent Res | 10.1177/00220345241287504 | 2025 | | |
| Identification of a Fusobacterial RNA-binding protein involved in host small RNA-mediated growth inhibition. | Dong PT, Yang M, Hu J, Cen L, Zhou P, Xu D, Xiong P, Li J, He X. | Int J Oral Sci | 10.1038/s41368-025-00378-4 | 2025 | | |
| Pathogenicity | Dual oxic-anoxic co-culture enables direct study of anaerobe-host interactions at the airway epithelial interface. | Moore PJ, Hoffman K, Ahmed S, Fletcher JR, Wiggen TD, Lucas SK, Arif SJ, Gilbertsen AJ, Kent LA, Fiege JK, Langlois RA, O'Grady SM, Hunter RC. | mBio | 10.1128/mbio.01338-24 | 2025 | |
| Enhancing fibroblast-epithelial cell communications: Serpine2 as a key molecule in Fusobacterium nucleatum-promoted colon cancer. | Li X, Luo S, Jiang Y, Ma Q, You F, Kuang Q, Fu X, Zheng C. | Front Immunol | 10.3389/fimmu.2025.1563922 | 2025 | | |
| Fusobacterium nucleatum-derived extracellular vesicles carrying virulence factor DNA trigger AIM2 inflammasome activation to facilitate UC progression. | Zhao Y, Wu R, Duan Y, Kong X, Zhang Y, You Y, Zhang J, Wang Y, Zhou L, Duan L. | Cell Mol Biol Lett | 10.1186/s11658-025-00817-4 | 2025 | | |
| Functional annotation of uncharacterized proteins from Fusobacterium nucleatum: identification of virulence factors. | Rauthan K, Joshi S, Kumar L, Goel D, Kumar S. | Genomics Inform | 10.5808/gi.22065 | 2023 | | |
| Fusobacterium nucleatum interacts with cancer-associated fibroblasts to promote colorectal cancer. | Karta J, Meyers M, Rodriguez F, Koncina E, Gilson C, Klein E, Gabola M, Benzarti M, Perez Escriva P, Molina Tijeras JA, Correia Tavares Bernardino C, Ponath F, Carpentier A, Pujabet MA, Schmoetten M, Tsenkova M, Saoud P, Gaigneaux A, Ternes D, Alonso L, Zugel N, Willemssen E, Koppes P, Leonard D, Casanova LP, Haan S, Mittelbronn M, Meiser J, Pozdeev VI, Vogel J, Nuciforo PG, Wilmes P, Letellier E. | EMBO J | 10.1038/s44318-025-00542-w | 2025 | | |
| An antisense oligomer conjugate with unpredicted bactericidal activity against Fusobacterium nucleatum. | Cosi V, Jung J, Popella L, Ponath F, Ghosh C, Barquist L, Vogel J. | mBio | 10.1128/mbio.00524-25 | 2025 | | |
| Metabolism | Characteristic metabolite profile of 10 colorectal cancer-related bacteria. | Liu Y, Mei W, Huang X, Yao X, Kong C, Chen Y. | Front Oncol | 10.3389/fonc.2025.1604876 | 2025 | |
| Antibacterial effect of femtosecond laser against Enterococcus faecalis and Fusobacterium nucleatum biofilms on dentin: an in vitro study. | Liu P, Liu R, Luo Y, Fan W, Fan B. | BMC Oral Health | 10.1186/s12903-025-05709-9 | 2025 | | |
| Pathogenicity | Oral Pathobiont-Derived Outer Membrane Vesicles in the Oral-Gut Axis. | Catalan EA, Seguel-Fuentes E, Fuentes B, Aranguiz-Varela F, Castillo-Godoy DP, Rivera-Asin E, Bocaz E, Fuentes JA, Bravo D, Schinnerling K, Melo-Gonzalez F. | Int J Mol Sci | 10.3390/ijms252011141 | 2024 | |
| Genetics | Interspecies interactions mediated by arginine metabolism enhance the stress tolerance of Fusobacterium nucleatum against Bifidobacterium animalis. | Zhou Z, Yang M, Fang H, Niu Y, Lu J, Ma Y, Zhang B, Zhu H, Chen P. | Microbiol Spectr | 10.1128/spectrum.02235-24 | 2025 | |
| Pathogenicity | Anti-Inflammatory Properties of Yellow Passion Fruit Bagasse Extract and Its Potential Role in Periodontal Wound Healing In Vitro. | Nogueira AVB, Faria LV, Lopes MES, Vigano J, Martinez J, Eick S, Cirelli JA, Deschner J. | Biomedicines | 10.3390/biomedicines13051134 | 2025 | |
| Pathogenicity | Fusobacterium nucleatum in Health and Disease. | Yang X, Zhang S, Ning T, Wu J. | MedComm (2020) | 10.1002/mco2.70465 | 2025 | |
| Apelin Counteracts the Effects of Fusobacterium nucleatum on the Migration of Periodontal Ligament Cells In Vitro. | Cores Ziskoven P, Nogueira AVB, Eick S, Deschner J. | Int J Mol Sci | 10.3390/ijms251910729 | 2024 | | |
| Fusobacterium nucleatum promotes colorectal cancer liver metastasis via miR-5692a/IL-8 axis by inducing epithelial-mesenchymal transition. | Yu Y, Yin H, Wu B, Zhao W, Wang Y, Aili A, Yang M, Yu Q, Yuan X. | J Biomed Sci | 10.1186/s12929-024-01097-4 | 2025 | | |
| Multi-omics analysis reveals the interplay between intratumoral bacteria and glioma. | Li T, Zhao Z, Peng M, Zhang L, Wang C, Luo F, Zeng M, Sun K, Fang Z, Luo Y, Xie Y, Lv C, Wang J, Huang J-D, Zhou H, Sun H. | mSystems | 10.1128/msystems.00457-24 | 2025 | | |
| In Vitro Eradication of Planktonic, Saliva and Biofilm Bacteria Using Lingonberry Extract as a Photosensitizer for Visible Light Plus Water-Filtered Infrared-A Irradiation. | Klein M, Al-Ahmad A, Follo M, Hellwig E, Vach K, Chrubasik-Hausmann S. | Nutrients | 10.3390/nu15234988 | 2023 | | |
| Development of a conditional plasmid for gene deletion in non-model Fusobacterium nucleatum strains. | Zhou P, G C B, Wu C. | Appl Environ Microbiol | 10.1128/aem.01816-24 | 2025 | | |
| The Role of Fusobacterium nucleatum in Colorectal Cancer Cell Proliferation and Migration. | Wu Z, Ma Q, Guo Y, You F. | Cancers (Basel) | 10.3390/cancers14215350 | 2022 | | |
| The surface protein Gbp of Fusobacterium nucleatum inhibits osteogenic differentiation by inactivating the Wnt/beta-catenin pathway via binding to Annexin A2. | Dong R, Li M, Gu XF, Gao H, Wei Z, Qi H, Zhang J, Feng Q. | J Transl Med | 10.1186/s12967-025-06569-1 | 2025 | | |
| Fusobacterium nucleatum downregulated MLH1 expression in colorectal cancer by activating autophagy-lysosome pathway | Ding T, Wu M, Zhao L, Liu H, Cao X, Guo J, Zhu X, Zhao L, Zhang H, Gao Y, Wei Q. | Front Immunol | 2025 | | ||
| The Influence of Selected Titanium Alloy Micro-Texture Parameters on Bacterial Adhesion. | Szymanska J, Krzywicka M, Kobus Z, Malm A, Grzegorczyk A. | Materials (Basel) | 10.3390/ma17194765 | 2024 | | |
| Secretory IgA dysfunction underlies poor prognosis in Fusobacterium-infected colorectal cancer. | Choi I, Kim KA, Kim SC, Park D, Nam KT, Cha JH, Baek S, Cha J, Jo HY, Jung M, Zeng MY, Matei I, Bullman S, Ahn JB, Han YD, Kim HS, Lee I. | Gut Microbes | 10.1080/19490976.2025.2528428 | 2025 | | |
| Pathogenicity | The Effect of Acute High-Altitude Exposure on Oral Pathogenic Bacteria and Salivary Oxi-Inflammatory Markers. | Pignatelli P, Mrakic-Sposta S, Bondi D, D'Antonio DL, Piattelli A, Santangelo C, Verratti V, Curia MC. | J Clin Med | 10.3390/jcm13206266 | 2024 | |
| Guanylate-binding protein 5-mediated autophagy can promote the clearance of intracellular F. nucleatum in dental pulp cells during pulpitis. | Huang M, Yang B, Yang X, Hou J, Li X. | BMC Oral Health | 10.1186/s12903-024-05295-2 | 2024 | | |
| Synergistic antimicrobial and probiotic activity of lactic acid bacteria isolated from Tarkhineh against Candida albicans. | Kiani A, Nami Y, Barghi A, Salehian M, Goudarzi F, Haghshenas B. | Sci Rep | 10.1038/s41598-025-07549-7 | 2025 | | |
| Elucidating the genotoxicity of Fusobacterium nucleatum-secreted mutagens in colorectal cancer carcinogenesis. | Xu W, Zhang Y, Chen D, Huang D, Zhao Y, Hu W, Lin L, Liu Y, Wang S, Zeng J, Xie C, Chan H, Li Q, Chen H, Liu X, Wong SH, Yu J, Chan FKL, Chan MTV, Ng SC, Wu WKK, Zhang L. | Gut Pathog | 10.1186/s13099-024-00640-w | 2024 | | |
| The Pathogenicity of Fusobacterium nucleatum Modulated by Dietary Fibers-A Possible Missing Link between the Dietary Composition and the Risk of Colorectal Cancer. | Nawab S, Bao Q, Ji LH, Luo Q, Fu X, Fan S, Deng Z, Ma W. | Microorganisms | 10.3390/microorganisms11082004 | 2023 | | |
| Integrated spatial multi-omics profiling of Fusobacterium nucleatum in breast cancer unveils its role in tumour microenvironment modulation and cancer progression. | Zhao F, An R, Ma Y, Yu S, Gao Y, Wang Y, Yu H, Xie X, Zhang J. | Clin Transl Med | 10.1002/ctm2.70273 | 2025 | | |
| Efficacy of Antimicrobial Peptide GH12 on a Multispecies Endodontic Biofilm Model: An In-vitro Study. | Sinha A, Taneja S, Shetty DC, Bhalla VK. | Eur Endod J | 10.14744/eej.2024.75983 | 2024 | | |
| Transcriptome | Integrative methylome and transcriptome analysis reveals epigenetic regulation of Fusobacterium nucleatum in laryngeal cancer. | Yuan X, Lau HC, Huang H, Hsueh CY, Gong H, Zhou L. | Microb Genom | 10.1099/mgen.0.001221 | 2024 | |
| A randomised, double-blind clinical study into the effect of zinc citrate trihydrate toothpaste on oral plaque microbiome ecology and function. | Adams SE, Cawley AK, Arnold D, Hoptroff MJ, Slomka V, Matheson JR, Marriott RE, Gemmell MR, Marsh PD. | Sci Rep | 10.1038/s41598-025-92545-0 | 2025 | | |
| The Impact of Silver Nanoparticles' Size on Biofilm Eradication. | Fakeeha G, AlHarbi S, Auda S, Balto H. | Int Dent J | 10.1016/j.identj.2024.08.007 | 2025 | | |
| Rapid detection of FadA in Fusobacterium nucleatum using the quantitative LAMP colorimetric phenol red method in stool samples from colorectal cancer patients. | Zuraik AA, Daboul Y, Awama MA, Yazigi H, Kayasseh MA, Georges M. | Sci Rep | 10.1038/s41598-024-62846-x | 2024 | | |
| Use of CRISPR interference for efficient and rapid gene inactivation in Fusobacterium nucleatum. | Zhou P, G C B, Stolte F, Wu C. | Appl Environ Microbiol | 10.1128/aem.01665-23 | 2024 | | |
| Fusobacterium nucleatum-induced imbalance in microbiome-derived butyric acid levels promotes the occurrence and development of colorectal cancer. | Wu QL, Fang XT, Wan XX, Ding QY, Zhang YJ, Ji L, Lou YL, Li X. | World J Gastroenterol | 10.3748/wjg.v30.i14.2018 | 2024 | | |
| Metabolism | Lipid accumulation inhibition strategies alleviate Fusobacterium nucleatum-infected colorectal cancer. | Zhou Z, Niu Y, Ma Y, Zhang D, Wang Y, Ji R, Zhao J, Ma C, Zhu H, Liu Y, Tu L, Lu J, Zhang B, Zhang H, Ma X, Chen P. | Microbiome | 10.1186/s40168-025-02133-7 | 2025 | |
| Stratification of Fusobacterium nucleatum by local health status in the oral cavity defines its subspecies disease association. | Krieger M, AbdelRahman YM, Choi D, Palmer EA, Yoo A, McGuire S, Kreth J, Merritt J. | Cell Host Microbe | 10.1016/j.chom.2024.02.010 | 2024 | | |
| Enzymology | Fusobacterium nucleatum: strategies for adapting to aerobic stress. | McGregor AK, Wolthers KR. | J Bacteriol | 10.1128/jb.00090-25 | 2025 | |
| Highly accurate measurement of the relative abundance of oral pathogenic bacteria using colony-forming unit-based qPCR. | Hwang J, Lee JH, Kim YJ, Hwang I, Kim YY, Kim HS, Park DY. | J Periodontal Implant Sci | 10.5051/jpis.2304520226 | 2024 | | |
| Enzymology | Revealing the potent probiotic properties and alcohol degradation capabilities of Lactiplantibacillus plantarum BGI-J9 by combining complete genomic and phenotypic analysis. | Fan Y, Ma Z, Wei B, Wen Y, Xu X, Rao X, Wu Z, Liu Y, Zhang H, Zhong Y, Zou Y, Xiao L. | Front Microbiol | 10.3389/fmicb.2025.1664033 | 2025 | |
| Analysis of Chemical Structure and Antibiofilm Properties of Exopolysaccharides from Lactiplantibacillus plantarum EIR/IF-1 Postbiotics. | Karaca B, Haliscelik O, Gursoy M, Kiran F, Loimaranta V, Soderling E, Gursoy UK. | Microorganisms | 10.3390/microorganisms10112200 | 2022 | | |
| Phylogeny | Lower fecal microbiota transplantation ameliorates ulcerative colitis by eliminating oral-derived Fusobacterium nucleatum and virulence factor. | Li DH, Li ZW, Sun Q, Wang L, Ning SB. | Gut Pathog | 10.1186/s13099-024-00633-9 | 2024 | |
| Microbes translocation from oral cavity to nasopharyngeal carcinoma in patients. | Liao Y, Wu YX, Tang M, Chen YW, Xie JR, Du Y, Wang TM, He YQ, Xue WQ, Zheng XH, Liu QY, Zheng MQ, Jia YJ, Tong XT, Zhou T, Li XZ, Yang DW, Diao H, Jia WH. | Nat Commun | 10.1038/s41467-024-45518-2 | 2024 | | |
| Fusobacterium nucleatum elicits subspecies-specific responses in human neutrophils. | Muchova M, Kuehne SA, Grant MM, Smith PP, Nagi M, Chapple ILC, Hirschfeld J. | Front Cell Infect Microbiol | 10.3389/fcimb.2024.1449539 | 2024 | | |
| Host-microbe computational proteomic landscape in oral cancer revealed key functional and metabolic pathways between Fusobacterium nucleatum and cancer progression. | Munoz-Grez CP, Vidal MA, Rojas TB, Ferrada LE, Zuniga FA, Vera AA, Sanhueza SA, Quiroga RA, Cabrera CD, Antilef BE, Cartes RA, Acevedo MP, Fraga MA, Alarcon-Zapata PF, Hernandez MA, Salas-Burgos AM, Tapia-Belmonte F, Yanez ML, Riquelme EM, Gonzalez WA, Rivera CA, Onate AA, Lamperti LI, Nova-Lamperti E. | Int J Oral Sci | 10.1038/s41368-024-00326-8 | 2025 | | |
| Characterization of Lactococcus lactis subspecies lactis strain Y-PDH01-07 isolated from traditional Indonesian fermented milk (dadih) as an oral probiotic candidate. | Astuti AK, Yasmon A, Louisa M, Wuyung PE, Washio J, Takahashi N, Wimardhani YS. | Sci Prog | 10.1177/00368504251383108 | 2025 | | |
| Exploring Antioxidant, Antimicrobial and Anti-Inflammatory Effects of Juglans regia and Pfaffia paniculata Extracts: Implications for Intestinal Dysbiosis and Colorectal Cancer Risk Associated with Oral Pathogens. | Miranda DG, Ramos LP, Attik N, Silva NVHF, Camargo PC, de Araujo GF, Lopes NFDS, Marcucci MC, Pacheco-Soares C, Godoi BH, Caires GA, Vigerelli H, Carrouel F. | Pharmaceutics | 10.3390/pharmaceutics17060693 | 2025 | | |
| Metabolism | Dasatinib and Quercetin Limit Gingival Senescence, Inflammation, and Bone Loss. | Rattanaprukskul K, Xia XJ, Hysa M, Jiang M, Hung M, Suslavich SF, Sahingur SE. | J Dent Res | 10.1177/00220345241299789 | 2025 | |
| Genetics | Isolation and characterization of novel Fusobacterium nucleatum bacteriophages. | Wang Y, Liu Z, Chen Q, Yi L, Xu Z, Cai M, Qin J, Zhang Y, Du G, Hong J, Guo X, Liu C. | Front Microbiol | 10.3389/fmicb.2022.945315 | 2022 | |
| Evaluation of Osteoconductive and Antimicrobial Properties of Novel Graphene on Dental Implants: An In Vitro Study. | Rayannavar S, Mv SK, Bembalgi M, Shankargouda S, Acharya A, Doddamani M, Hiremath V, Shah MA. | Cureus | 10.7759/cureus.54172 | 2024 | | |
| Reexamining the role of Fusobacterium nucleatum subspecies in clinical and experimental studies. | Krieger M, Guo M, Merritt J. | Gut Microbes | 10.1080/19490976.2024.2415490 | 2024 | | |
| Pathogenicity | Regulation of gingival keratinocyte monocyte chemoattractant protein-1-induced protein (MCPIP)-1 and mucosa-associated lymphoid tissue lymphoma translocation protein (MALT)-1 expressions by periodontal bacteria, lipopolysaccharide, and interleukin-1beta. | Firatli Y, Firatli E, Loimaranta V, Elmanfi S, Gursoy UK. | J Periodontol | 10.1002/jper.22-0093 | 2023 | |
| Assessing the quality of the anaerobic environment - a method developed to support EUCAST disk diffusion of anaerobic bacteria. | Justesen US, Ahman J, Matuschek E, Kahlmeter G. | Eur J Clin Microbiol Infect Dis | 10.1007/s10096-023-04622-9 | 2023 | | |
| Engineered bacterial membrane biomimetic covalent organic framework as nano-immunopotentiator for cancer immunotherapy. | Yang QC, Wang YY, Wang S, Song A, Wang WD, Zhang L, Sun ZJ. | Bioact Mater | 10.1016/j.bioactmat.2025.01.018 | 2025 | | |
| Fusobacterium nucleatum subsp. nucleatum RadD binds Siglec-7 and inhibits NK cell-mediated cancer cell killing. | Galaski J, Rishiq A, Liu M, Bsoul R, Bergson A, Lux R, Bachrach G, Mandelboim O. | iScience | 10.1016/j.isci.2024.110157 | 2024 | | |
| Leucine restriction ameliorates Fusobacterium nucleatum-driven malignant progression and radioresistance in nasopharyngeal carcinoma. | Guo S, Xing S, Wu Z, Chen F, Pan X, Li Q, Liu W, Zhang G. | Cell Rep Med | 10.1016/j.xcrm.2024.101753 | 2024 | | |
| 3D Printed Bigel: A Novel Delivery System for Cannabidiol-Rich Hemp Extract. | Gosciniak A, Kocaj F, Stasilowicz-Krzemien A, Szymanski M, Karpinski TM, Cielecka-Piontek J. | Gels | 10.3390/gels10120770 | 2024 | | |
| A new member of the flavodoxin superfamily from Fusobacterium nucleatum that functions in heme trafficking and reduction of anaerobilin. | McGregor AK, Chan ACK, Schroeder MD, Do LTM, Saini G, Murphy MEP, Wolthers KR. | J Biol Chem | 10.1016/j.jbc.2023.104902 | 2023 | | |
| Fusobacterium nucleatum Infection Induces Malignant Proliferation of Esophageal Squamous Cell Carcinoma Cell by Putrescine Production. | Ding N, Cheng Y, Liu H, Wu Y, Weng Y, Cui H, Cheng C, Zhang W, Cui Y. | Microbiol Spectr | 10.1128/spectrum.02759-22 | 2023 | | |
| Pathogenicity | Viridans Streptococcal Biofilm Evades Immune Detection and Contributes to Inflammation and Rupture of Atherosclerotic Plaques. | Karhunen PJ, Pessi T, Horkko S, Karhunen V, Goebeler S, Louhelainen AM, Martiskainen M, Haapaniemi T, Lappetelainen J, Ijas T, Lyytikainen LP, Raitoharju E, Sioris T, Tuomisto S, Huhtala H, Wang C, Monaco C, Oksala N, Lehtimaki T, Laaksonen R. | J Am Heart Assoc | 10.1161/jaha.125.041521 | 2025 | |
| Periodontitis promotes tumor growth and immune evasion via PD-1/PD-L1. | Wang S, Nie F, Yin Q, Tian H, Gong P, Ju J, Liu J, Yang P, Yang C. | Cancer Immunol Immunother | 10.1007/s00262-024-03865-5 | 2024 | | |
| Effects of Labrador Tea, Peppermint, and Winter Savory Essential Oils on Fusobacterium nucleatum. | Ben Lagha A, Vaillancourt K, Maquera Huacho P, Grenier D. | Antibiotics (Basel) | 10.3390/antibiotics9110794 | 2020 | | |
| Fusobacterium nucleatum promotes colorectal cancer through neogenesis of tumor stem cells. | Wang Q, Hu T, Zhang Q, Zhang Y, Dong X, Jin Y, Li J, Guo Y, Guo F, Chen Z, Zhong P, Yang Y, Ma Y. | J Clin Invest | 10.1172/jci181595 | 2025 | | |
| Pathogenicity | Synergistic induction of PGE2 by oral pathogens and TNF promotes gingival fibroblast-driven stromal-immune cross-talk in periodontitis. | Nieboga E, Schuster A, Drapala DM, Melnykova M, Gut A, Lipska W, Kwitniewski M, Migaczewski M, Czesnikiewicz-Guzik M, Kaczmarzyk T, Potempa J, Grabiec AM. | mBio | 10.1128/mbio.00046-25 | 2025 | |
| Xylityl Sesquicaprylate Efficacy as an Antiseptic Ingredient for Oral Care Products (Mouthwash): An In Vitro Screening Investigation against Eight Microorganisms. | Nogueira C, Mussi L, Baby AR, Zupeli R, Magalhaes WV. | Molecules | 10.3390/molecules28010028 | 2022 | | |
| Targeting Fusobacterium nucleatum through chemical modifications of host-derived transfer RNA fragments. | Yang M, Dong PT, Cen L, Shi W, He X, Li J. | ISME J | 10.1038/s41396-023-01398-w | 2023 | | |
| Antibacterial Efficacy and Surface Characteristics of Boron Nitride Coated Dental Implant: An In-Vitro Study. | Raval A, S Yadav N, Narwani S, Somkuwar K, Verma V, Almubarak H, Alqahtani SM, Tasleem R, Luke AM, Kuriadom ST, Karobari MI. | J Funct Biomater | 10.3390/jfb14040201 | 2023 | | |
| Phylogeny | Enrichment of Prevotella intermedia in human colorectal cancer and its additive effects with Fusobacterium nucleatum on the malignant transformation of colorectal adenomas. | Lo CH, Wu DC, Jao SW, Wu CC, Lin CY, Chuang CH, Lin YB, Chen CH, Chen YT, Chen JH, Hsiao KH, Chen YJ, Chen YT, Wang JY, Li LH. | J Biomed Sci | 10.1186/s12929-022-00869-0 | 2022 | |
| Fusobacterium nucleatum triggers senescence phenotype in gingival epithelial cells. | Albuquerque-Souza E, Shelling B, Jiang M, Xia XJ, Rattanaprukskul K, Sahingur SE. | Mol Oral Microbiol | 10.1111/omi.12432 | 2024 | | |
| Effect of three oral pathogens on the TMA-TMAO metabolic pathway. | Wang X, Chen L, Teng Y, Xie W, Huang L, Wu J, Wang H, Xie S. | Front Cell Infect Microbiol | 10.3389/fcimb.2024.1413787 | 2024 | | |
| Effect of Bacterial Infection on Ghrelin Receptor Regulation in Periodontal Cells and Tissues. | Nogueira AVB, Nokhbehsaim M, Damanaki A, Eick S, Beisel-Memmert S, Kirschneck C, Schroder A, Cirelli T, Leguizamon NDP, Cirelli JA, Deschner J. | Int J Mol Sci | 10.3390/ijms23063039 | 2022 | | |
| Interspecies metabolite transfer fuels the methionine metabolism of Fusobacterium nucleatum to stimulate volatile methyl mercaptan production. | Hara T, Sakanaka A, Lamont RJ, Amano A, Kuboniwa M. | mSystems | 10.1128/msystems.00764-23 | 2024 | | |
| Assessment of the Effect on Periodontitis of Antibiotic Therapy and Bacterial Lysate Treatment. | Ancuta DL, Alexandru DM, Muselin F, Cristina RT, Coman C. | Int J Mol Sci | 10.3390/ijms25105432 | 2024 | | |
| Fusobacterium nucleatum infection-induced neurodegeneration and abnormal gut microbiota composition in Alzheimer's disease-like rats. | Yan C, Diao Q, Zhao Y, Zhang C, He X, Huang R, Li Y. | Front Neurosci | 10.3389/fnins.2022.884543 | 2022 | | |
| Effect of sodium hypochlorite gel on bacteria associated with periodontal disease. | Irani D, Jungbauer G, Sculean A, Eick S. | Clin Oral Investig | 10.1007/s00784-023-05446-9 | 2024 | | |
| Fusobacterium nucleatum promotes liver metastasis in colorectal cancer by regulating the hepatic immune niche and altering gut microbiota. | Yin H, Miao Z, Wang L, Su B, Liu C, Jin Y, Wu B, Han H, Yuan X. | Aging (Albany NY) | 10.18632/aging.203914 | 2022 | | |
| Fusobacterium nucleatum subsp. polymorphum recovered from malignant and potentially malignant oral disease exhibit heterogeneity in adhesion phenotypes and adhesin gene copy number, shaped by inter-subspecies horizontal gene transfer and recombination-derived mosaicism. | Crowley C, Selvaraj A, Hariharan A, Healy CM, Moran GP. | Microb Genom | 10.1099/mgen.0.001217 | 2024 | | |
| Detection of Fusobacterium nucleatum DNA in primary care patient stool samples does not predict progression of colorectal neoplasia. | Aitchison A, Pearson JF, Purcell RV, Frizelle FA, Keenan JI. | PLoS One | 10.1371/journal.pone.0269541 | 2022 | | |
| Evaluation of the antibacterial activity of Elsholtzia ciliate essential oil against halitosis-related Fusobacterium nucleatum and Porphyromonas gingivalis. | Li F, Wang C, Xu J, Wang X, Cao M, Wang S, Zhang T, Xu Y, Wang J, Pan S, Hu W. | Front Microbiol | 10.3389/fmicb.2023.1219004 | 2023 | | |
| Fusobacterium nucleatum Subspecies Differ in Biofilm Forming Ability in vitro. | Muchova M, Balacco DL, Grant MM, Chapple ILC, Kuehne SA, Hirschfeld J. | Front Oral Health | 10.3389/froh.2022.853618 | 2022 | | |
| Clinical and microbiological assessment in a subpopulation of young Argentine patients with severe periodontitis. | Pontarolo C, Bozza FL, Galli FG, Bonta H, Molgatini SL, Caride F, Gliosca LA. | Acta Odontol Latinoam | 10.54589/aol.36/1/24 | 2023 | | |
| Phytochemical Composition and Bioactivities of Some Hydrophytes: Antioxidant, Antiparasitic, Antibacterial, and Anticancer Properties and Mechanisms. | Alharthi F, Althagafi HA, Jafri I, Oyouni AAA, Althaqafi MM, Al-Hijab LYA, Al-Hazmi NE, Elagib SM, Naguib DM. | Plants (Basel) | 10.3390/plants13152148 | 2024 | | |
| Exploring the interplay between Fusobacterium nucleatum with the expression of microRNA, and inflammatory mediators in colorectal cancer. | Bostanghadiri N, Razavi S, Shariati A, Talebi M, Mirkalantari S, Emami Razavi A, Darban-Sarokhalil D. | Front Microbiol | 10.3389/fmicb.2023.1302719 | 2023 | | |
| Beneficial effects of non-invasive physical plasma on human periodontal ligament cells in vitro. | Eggers B, Seher L, Marciniak J, Pauck T, Deschner J, Eick S, Stope MB, Kramer FJ, Kuchler EC, Kirschneck C, Nokhbehsaim M, Beisel-Memmert S. | Front Med (Lausanne) | 10.3389/fmed.2024.1443368 | 2024 | | |
| Porphyromonas gingivalis diffusible signaling molecules enhance Fusobacterium nucleatum biofilm formation via gene expression modulation. | Yamaguchi-Kuroda Y, Kikuchi Y, Kokubu E, Ishihara K. | J Oral Microbiol | 10.1080/20002297.2023.2165001 | 2023 | | |
| Fabrication of N-halamine coatings with long-lasting bacterial inhibition and bacterial biofilm disruption functions for invisible aligner applications. | Zhou Z, Liu X, Mei L, Guo X, Gao Y, Hao Y. | Mater Today Bio | 10.1016/j.mtbio.2025.102112 | 2025 | | |
| The role of CXCL2-mediated crosstalk between tumor cells and macrophages in Fusobacterium nucleatum-promoted oral squamous cell carcinoma progression. | Nie F, Zhang J, Tian H, Zhao J, Gong P, Wang H, Wang S, Yang P, Yang C. | Cell Death Dis | 10.1038/s41419-024-06640-7 | 2024 | | |
| Antibacterial activity and biocompatibility of silver coating via aerosol deposition on titanium and zirconia surfaces. | Choi S, Jo YH, Han JS, Yoon HI, Lee JH, Yeo IL. | Int J Implant Dent | 10.1186/s40729-023-00488-w | 2023 | | |
| Strain-level detection of Fusobacterium nucleatum in colorectal cancer specimens by targeting the CRISPR-Cas region. | Shimomura Y, Sugi Y, Kume A, Tanaka W, Yoshihara T, Matsuura T, Komiya Y, Ogata Y, Suda W, Hattori M, Higurashi T, Nakajima A, Matsumoto M. | Microbiol Spectr | 10.1128/spectrum.05123-22 | 2023 | | |
| In vitro assessment of the antimicrobial activity of tetracycline hydrochloride diluted in three different vehicles against Porphyromonas gingivalis, Prevotella intermedia, and Fusobacterium nucleatum. | Escalante-Herrera A, Chaves M, Villamil JC, Roa NS. | J Indian Soc Periodontol | 10.4103/jisp.jisp_661_20 | 2022 | | |
| Fusobacterium nucleatum facilitates proliferation and autophagy by activating miR-361-3p/NUDT1 axis through oxidative stress in hypopharyngeal squamous cell carcinoma. | Lau HC, Yuan X, Huang H, Zhang M, Hsueh CY, Gong H. | BMC Cancer | 10.1186/s12885-023-11439-4 | 2023 | | |
| The Anti-Biofilm Properties of Phloretin and Its Analogs against Porphyromonas gingivalis and Its Complex Flora. | Wu D, Hao L, Liu X, Li X, Zhao G. | Foods | 10.3390/foods13131994 | 2024 | | |
| Apelin Enhances the Effects of Fusobacterium nucleatum on Periodontal Ligament Cells In Vitro. | Cores Ziskoven P, Nogueira AVB, Gutierrez LS, Weusmann J, Eick S, Buduneli N, Deschner J. | Int J Mol Sci | 10.3390/ijms24054733 | 2023 | | |
| Induction of Experimental Peri-Implantitis with Strains Selected from the Human Oral Microbiome. | Ancuta DL, Alexandru DM, Crivineanu M, Coman C. | Biomedicines | 10.3390/biomedicines12040715 | 2024 | | |
| Transcriptome | Fusobacterium nucleatum promotes colon cancer progression by changing the mucosal microbiota and colon transcriptome in a mouse model. | Wu N, Feng YQ, Lyu N, Wang D, Yu WD, Hu YF. | World J Gastroenterol | 10.3748/wjg.v28.i18.1981 | 2022 | |
| Exacerbation of diabetes due to F. Nucleatum LPS-induced SGLT2 overexpression in the renal proximal tubular epithelial cells. | Seki A, Kajiwara K, Teramachi J, Egusa M, Miyawaki T, Sawa Y. | BMC Nephrol | 10.1186/s12882-025-03965-z | 2025 | | |
| Study of the inflammatory activating process in the early stage of Fusobacterium nucleatum infected PDLSCs. | Wang Y, Wang L, Sun T, Shen S, Li Z, Ma X, Gu X, Zhang X, Peng A, Xu X, Feng Q. | Int J Oral Sci | 10.1038/s41368-022-00213-0 | 2023 | | |
| Fusobacterium nucleatum-triggered purine metabolic reprogramming drives tumorigenesis in head and neck carcinoma. | Li F, Huang H, Xu J, Tao L, Zhou L, Hsueh C, Gong H, Zhang M. | Discov Oncol | 10.1007/s12672-023-00727-x | 2023 | | |
| Electrospun Nanofibers with Pomegranate Peel Extract as a New Concept for Treating Oral Infections. | Paczkowska-Walendowska M, Ignacyk M, Miklaszewski A, Plech T, Karpinski TM, Kwiatek J, Swora-Cwynar E, Walendowski M, Cielecka-Piontek J. | Materials (Basel) | 10.3390/ma17112558 | 2024 | | |
| Salivary pellicle modulates biofilm formation on titanium surfaces. | Martinez-Hernandez M, Reyes-Grajeda JP, Hannig M, Almaguer-Flores A. | Clin Oral Investig | 10.1007/s00784-023-05230-9 | 2023 | | |
| Metabolism | Fucose ameliorates the proinflammatory property of Fusobacterium nucleatum in colitis via altering its metabolism. | Duan C, Hou L, Deng X, Wu J, Qian W, Han C, Hou X. | Front Cell Infect Microbiol | 10.3389/fcimb.2023.1190602 | 2023 | |
| The effect of surface material, roughness and wettability on the adhesion and proliferation of Streptococcus gordonii, Fusobacterium nucleatum and Porphyromonas gingivalis. | Choi S, Jo YH, Luke Yeo IS, Yoon HI, Lee JH, Han JS. | J Dent Sci | 10.1016/j.jds.2022.09.010 | 2023 | | |
| Fucosyltransferases Regulated by Fusobacterium Nucleatum and Act as Novel Biomarkers in Colon Adenocarcinoma. | Wang P, Liu X, Yu J, Meng Z, Lv Z, Shang C, Geng Q, Wang D, Xue D, Li L. | J Inflamm Res | 10.2147/jir.s396484 | 2023 | | |
| Frankincense (Boswellia serrata) Extract Effects on Growth and Biofilm Formation of Porphyromonas gingivalis, and Its Intracellular Infection in Human Gingival Epithelial Cells. | Vang D, Moreira-Souza ACA, Zusman N, Moncada G, Matshik Dakafay H, Asadi H, Ojcius DM, Almeida-da-Silva CLC. | Curr Issues Mol Biol | 10.3390/cimb46040187 | 2024 | | |
| The Impact of Lactobacillus reuteri on Oral and Systemic Health: A Comprehensive Review of Recent Research. | Liu Z, Cao Q, Wang W, Wang B, Yang Y, Xian CJ, Li T, Zhai Y. | Microorganisms | 10.3390/microorganisms13010045 | 2024 | | |
| Locally producing antibacterial peptide to deplete intratumoral pathogen for preventing metastatic breast cancer. | Geng S, Xiang T, Shi Y, Cao M, Wang D, Wang J, Li X, Song H, Zhang Z, Shi J, Liu J, Li A, Sun K. | Acta Pharm Sin B | 10.1016/j.apsb.2025.01.002 | 2025 | | |
| Intratumoral Fusobacterium nucleatum Recruits Tumor-Associated Neutrophils to Promote Gastric Cancer Progression and Immune Evasion. | Zhang T, Li Y, Zhai E, Zhao R, Qian Y, Huang Z, Liu Y, Zhao Z, Xu X, Liu J, Li Z, Liang Z, Wei R, Ye L, Ma J, Wu Q, Chen J, Cai S. | Cancer Res | 10.1158/0008-5472.can-24-2580 | 2025 | | |
| Akkermansia muciniphila inhibited the periodontitis caused by Fusobacterium nucleatum. | Song B, Xian W, Sun Y, Gou L, Guo Q, Zhou X, Ren B, Cheng L. | NPJ Biofilms Microbiomes | 10.1038/s41522-023-00417-0 | 2023 | | |
| Genetics | A newly developed PCR-based method revealed distinct Fusobacterium nucleatum subspecies infection patterns in colorectal cancer. | Bi D, Zhu Y, Gao Y, Li H, Zhu X, Wei R, Xie R, Wei Q, Qin H. | Microb Biotechnol | 10.1111/1751-7915.13900 | 2021 | |
| Antibacterial and Bactericidal Effects of the Er: YAG Laser on Oral Bacteria: A Systematic Review of Microbiological Evidence. | Fiegler-Rudol J, Skaba D, Kawczyk-Krupka A, Wiench R. | J Funct Biomater | 10.3390/jfb16060209 | 2025 | | |
| Fusobacterium nucleatum Metabolically Integrates Commensals and Pathogens in Oral Biofilms. | Sakanaka A, Kuboniwa M, Shimma S, Alghamdi SA, Mayumi S, Lamont RJ, Fukusaki E, Amano A. | mSystems | 10.1128/msystems.00170-22 | 2022 | | |
| Phenotype | High-Frequency Ultrasound for Detecting Periodontal Inflammation: A Preclinical Diagnostic Accuracy Study. | Samal A, Majzoub J, Rodriguez Betancourt A, Webber L, Mazzocco J, Wang HL, Castilho R, Fenno JC, Chan HL, Kripfgans OD. | J Periodontal Res | 10.1111/jre.13376 | 2025 | |
| Clinical Significance of Fusobacterium nucleatum and Microsatellite Instability in Evaluating Colorectal Cancer Prognosis. | Xie Y, Jiao X, Zeng M, Fan Z, Li X, Yuan Y, Zhang Q, Xia Y, Xia Y. | Cancer Manag Res | 10.2147/cmar.s382464 | 2022 | | |
| Evaluation of Fusobacterium nucleatum Enoyl-ACP Reductase (FabK) as a Narrow-Spectrum Drug Target. | Rutherford JT, Avad K, Dureja C, Norseeda K, Gc B, Wu C, Sun D, Hevener KE, Hurdle JG. | ACS Infect Dis | 10.1021/acsinfecdis.3c00710 | 2024 | | |
| Fusobacterium nucleatum induces excess methyltransferase-like 3-mediated microRNA-4717-3p maturation to promote colorectal cancer cell proliferation. | Xu Q, Lu X, Li J, Feng Y, Tang J, Zhang T, Mao Y, Lan Y, Luo H, Zeng L, Xiang Y, Hu L, Zhang Y, Li Q, Deng L, He X, Tang B, Mao X, Zeng D. | Cancer Sci | 10.1111/cas.15536 | 2022 | | |
| Implementing the Design of Experiments (DoE) Concept into the Development of Mucoadhesive Tablets Containing Orange Peel Extract as a Potential Concept for the Treatment of Oral Infections. | Paczkowska-Walendowska M, Karpinski TM, Garbiec E, Walendowski M, Cielecka-Piontek J. | Materials (Basel) | 10.3390/ma17215234 | 2024 | | |
| Periodontopathic Bacterium Fusobacterium nucleatum Affects Matrix Metalloproteinase-9 Expression in Human Alveolar Epithelial Cells and Mouse Lung. | Suzuki R, Kamio N, Sugimoto K, Maruoka S, Gon Y, Kaneko T, Yonehara Y, Imai K. | In Vivo | 10.21873/invivo.12749 | 2022 | | |
| Fusobacterium nucleatum induces a tumor microenvironment with diminished adaptive immunity against colorectal cancers. | Kim HS, Kim CG, Kim WK, Kim KA, Yoo J, Min BS, Paik S, Shin SJ, Lee H, Lee K, Kim H, Shin EC, Kim TM, Ahn JB. | Front Cell Infect Microbiol | 10.3389/fcimb.2023.1101291 | 2023 | | |
| Pathogenicity | Non-Invasive Physical Plasma Reduces the Inflammatory Response in Microbially Prestimulated Human Gingival Fibroblasts | Eggers B, Stope M, Marciniak J, Mustea A, Eick S, Deschner J, Nokhbehsaim M, Kramer F. | Int J Mol Sci | 2023 | | |
| Enzymology | Enhanced Fusobacterium nucleatum Genetics Using Host DNA Methyltransferases To Bypass Restriction-Modification Systems. | Umana A, Nguyen TTD, Sanders BE, Williams KJ, Wozniak B, Slade DJ. | J Bacteriol | 10.1128/jb.00279-22 | 2022 | |
| In vitro activity of anti-rheumatic drugs on release of pro-inflammatory cytokines from oral cells in interaction with microorganisms. | Stahli A, Scherler C, Zappala G, Sculean A, Eick S. | Front Oral Health | 10.3389/froh.2022.960732 | 2022 | | |
| Fn-Dps, a novel virulence factor of Fusobacterium nucleatum, disrupts erythrocytes and promotes metastasis in colorectal cancer. | Wu Y, Guo S, Chen F, Li Y, Huang Y, Liu W, Zhang G. | PLoS Pathog | 10.1371/journal.ppat.1011096 | 2023 | | |
| Utilizing a naturopathic mouthwash with selective antimicrobial effects against multispecies oral biofilms for prevention of dysbiosis | Siddiqui D, Tsai Y, Giron Bastidas J, Jazaeri M, Kotsakis G. | Front Oral Health | 2025 | | ||
| A comparative assessment of pomegranate extract, sodium hypochlorite, chlorhexidine, Myrrh (Commiphora molmol), tulsi extract against Enterococcus faecalis, Fusobacterium nucleatum and Staphylococci epidermidis. | Sisodiya M, Ahmed S, Sengupta R, Priyanka, Saha AK, Verma G. | J Oral Maxillofac Pathol | 10.4103/0973-029x.325252 | 2021 | | |
| Optimized Antimicrobial Peptide Jelleine-I Derivative Br-J-I Inhibits Fusobacterium Nucleatum to Suppress Colorectal Cancer Progression. | Jia F, Yu Q, Wang R, Zhao L, Yuan F, Guo H, Guo H, Shen Y, He F. | Int J Mol Sci | 10.3390/ijms24021469 | 2023 | | |
| A Probiotic Formula for Modulation of Colorectal Cancer Risk via Reducing CRC-Associated Bacteria. | Liang JQ, Zeng Y, Lau EYT, Sun Y, Huang Y, Zhou T, Xu Z, Yu J, Ng SC, Chan FKL. | Cells | 10.3390/cells12091244 | 2023 | | |
| Fusobacterium nucleatum and its metabolite hydrogen sulfide alter gut microbiota composition and autophagy process and promote colorectal cancer progression. | Wang M, Wang Z, Lessing DJ, Guo M, Chu W. | Microbiol Spectr | 10.1128/spectrum.02292-23 | 2023 | | |
| Fusobacterium nucleatum induces colon anastomosis leak by activating epithelial cells to express MMP9. | Shi S, Liu Y, Wang Z, Jin X, Yan W, Guo X, Lin B, Wang H, Li B, Zheng J, Wei Y. | Front Microbiol | 10.3389/fmicb.2022.1031882 | 2022 | | |
| Effects of Green Tea Extract Epigallocatechin-3-Gallate on Oral Diseases: A Narrative Review. | Li Y, Cheng L, Li M. | Pathogens | 10.3390/pathogens13080634 | 2024 | | |
| Sodium New Houttuyfonate Inhibits Cancer-Promoting Fusobacterium nucleatum (Fn) to Reduce Colorectal Cancer Progression. | Jia F, Yu Q, Zhao L, Shen Y, Guo H, Guo H, He F. | Cancers (Basel) | 10.3390/cancers14246111 | 2022 | | |
| Oral Porphyromonas gingivalis and Fusobacterium nucleatum Abundance in Subjects in Primary and Secondary Cardiovascular Prevention, with or without Heterozygous Familial Hypercholesterolemia. | Curia MC, Pignatelli P, D'Antonio DL, D'Ardes D, Olmastroni E, Scorpiglione L, Cipollone F, Catapano AL, Piattelli A, Bucci M, Magni P. | Biomedicines | 10.3390/biomedicines10092144 | 2022 | | |
| Intracellular Fusobacterium nucleatum infection attenuates antitumor immunity in esophageal squamous cell carcinoma. | Li Y, Xing S, Chen F, Li Q, Dou S, Huang Y, An J, Liu W, Zhang G. | Nat Commun | 10.1038/s41467-023-40987-3 | 2023 | | |
| Genetics | Pangenomic Study of Fusobacterium nucleatum Reveals the Distribution of Pathogenic Genes and Functional Clusters at the Subspecies and Strain Levels. | Ma X, Sun T, Zhou J, Zhi M, Shen S, Wang Y, Gu X, Li Z, Gao H, Wang P, Feng Q. | Microbiol Spectr | 10.1128/spectrum.05184-22 | 2023 | |
| Metabolism | Genetic Determinants of Hydrogen Sulfide Biosynthesis in Fusobacterium nucleatum Are Required for Bacterial Fitness, Antibiotic Sensitivity, and Virulence. | Chen YW, Camacho MI, Chen Y, Bhat AH, Chang C, Peluso EA, Wu C, Das A, Ton-That H. | mBio | 10.1128/mbio.01936-22 | 2022 | |
| Fusobacterium nucleatum triggers proinflammatory cell death via Z-DNA binding protein 1 in apical periodontitis. | Liu H, Liu Y, Fan W, Fan B. | Cell Commun Signal | 10.1186/s12964-022-01005-z | 2022 | | |
| Antibiofilm activity and NMR-based metabolomic characterization of cell-free supernatant of Limosilactobacillus reuteri DSM 17938. | Vitale I, Spano M, Puca V, Carradori S, Cesa S, Marinacci B, Sisto F, Roos S, Grompone G, Grande R. | Front Microbiol | 10.3389/fmicb.2023.1128275 | 2023 | | |
| A polyvalent vaccine for selectively killing tumor-associated bacteria to prevent cancer metastasis. | Kang Z, Chen L, Li P, Zheng Z, Shen J, Xiao Z, Miao Y, Yang Y, Chen Q. | Sci Adv | 10.1126/sciadv.adt0341 | 2025 | | |
| A Comparative Analysis of the Efficacy of Bacterial Lysate versus Antibiotic Therapy in the Treatment of Experimental Peri-Implantitis in Rats. | Ancuta DL, Alexandru DM, Tucureanu C, Coman C. | Microorganisms | 10.3390/microorganisms12081537 | 2024 | | |
| Fusobacterium nucleatum promotes colorectal cancer metastasis by excretion of miR-122-5p from cells via exosomes. | Zhang M, Wang Y, Yu L, Zhang Y, Wang Y, Shang Z, Xin Y, Li X, Ning N, Zhang Y, Zhang X. | iScience | 10.1016/j.isci.2023.107686 | 2023 | | |
| Galleria mellonella as an experimental model for studying periodontopathogens. | Santos TA, Scorzoni L, Santos AC, Junqueira JC, Anbinder AL. | J Indian Soc Periodontol | 10.4103/jisp.jisp_631_19 | 2020 | | |
| Pathogenicity | Outer Membrane Vesicles From Fusobacterium nucleatum Switch M0-Like Macrophages Toward the M1 Phenotype to Destroy Periodontal Tissues in Mice. | Chen G, Sun Q, Cai Q, Zhou H. | Front Microbiol | 10.3389/fmicb.2022.815638 | 2022 | |
| Hypochlorous acid solution serves as a potential anti-biofilm therapy for periodontitis via targeting quorum sensing of periodontal pathogens. | Lv X, Han X, Yang Y, Ma Y, Wang Y, Zhang K, Wang F, Yang C, Yan K, Wang X. | J Oral Microbiol | 10.1080/20002297.2025.2557959 | 2025 | | |
| Structural Basis of the Inhibition of L-Methionine gamma-Lyase from Fusobacterium nucleatum. | Bu T, Lan J, Jo I, Zhang J, Bai X, He S, Jin X, Wang L, Jin Y, Jin X, Zhang L, Piao H, Ha NC, Quan C, Nam KH, Xu Y. | Int J Mol Sci | 10.3390/ijms24021651 | 2023 | | |
| Metabolism | Nano-mupirocin as tumor-targeted antibiotic: Physicochemical, immunotoxicological and pharmacokinetic characterization, and effect on gut microbiome. | Cern A, Skoczen SL, Snapp KS, Hod A, Zilbersheid D, Bavli Y, Alon-Maimon T, Bachrach G, Wei X, Berman B, Yassour M, Cedrone E, Neun BW, Dobrovolskaia MA, Clogston JD, Stern ST, Barenholz Y. | J Control Release | 10.1016/j.jconrel.2024.07.045 | 2024 | |
| Fusobacterium nucleatum exacerbates chronic obstructive pulmonary disease in elastase-induced emphysematous mice. | Suzuki R, Kamio N, Kaneko T, Yonehara Y, Imai K. | FEBS Open Bio | 10.1002/2211-5463.13369 | 2022 | | |
| Pathogenicity | A concerted probiotic activity to inhibit periodontitis-associated bacteria. | Jansen PM, Abdelbary MMH, Conrads G. | PLoS One | 10.1371/journal.pone.0248308 | 2021 | |
| Identification of Fusobacterium Species Using Matrix-Assisted Laser Desorption/Ionization-Time-of-Flight Mass Spectrometry by Updating ASTA CoreDB. | Yun SY, Lee Y, Hong J, Kim DC, Lee H, Yong D, Lim YK, Kook JK, Lee K. | Yonsei Med J | 10.3349/ymj.2022.0271 | 2022 | | |
| Antibacterial, Antiparasitic, and Cytotoxic Activities of Chemical Characterized Essential Oil of Chrysopogon zizanioides Roots. | Oliveira TAS, Vieira TM, Esperandim VR, Martins CHG, Magalhaes LG, Miranda MLD, Crotti AEM. | Pharmaceuticals (Basel) | 10.3390/ph15080967 | 2022 | | |
| Pathogenicity | Fusobacterium nucleatum mediates endothelial damage and increased permeability following single species and polymicrobial infection. | Farrugia C, Stafford GP, Gains AF, Cutts AR, Murdoch C. | J Periodontol | 10.1002/jper.21-0671 | 2022 | |
| Modulation of Intratumoral Fusobacterium nucleatum to Enhance Sonodynamic Therapy for Colorectal Cancer with Reduced Phototoxic Skin Injury. | Qu X, Yin F, Pei M, Chen Q, Zhang Y, Lu S, Zhang X, Liu Z, Li X, Chen H, Zhang Y, Qin H. | ACS Nano | 10.1021/acsnano.3c01308 | 2023 | | |
| Impact of Fusobacterium nucleatum in the gastrointestinal tract on natural killer cells. | Kim YJ, Kim BK, Park SJ, Kim JH. | World J Gastroenterol | 10.3748/wjg.v27.i29.4879 | 2021 | | |
| An Extracytoplasmic Function Sigma/Anti-Sigma Factor System Regulates beta-Glucanase Expression in Tannerella forsythia in Response to Fusobacterium nucleatum Sensing. | Honma K, Sasaki H, Hamada N, Sharma A. | J Bacteriol | 10.1128/jb.00313-22 | 2022 | | |
| Fusobacterium nucleatum Acts as a Pro-carcinogenic Bacterium in Colorectal Cancer: From Association to Causality. | Wang S, Liu Y, Li J, Zhao L, Yan W, Lin B, Guo X, Wei Y. | Front Cell Dev Biol | 10.3389/fcell.2021.710165 | 2021 | | |
| Fusobacterium nucleatum outer membrane vesicles activate autophagy to promote oral cancer metastasis. | Chen G, Gao C, Jiang S, Cai Q, Li R, Sun Q, Xiao C, Xu Y, Wu B, Zhou H. | J Adv Res | 10.1016/j.jare.2023.04.002 | 2024 | | |
| Induction of Periodontitis Using Bacterial Strains Isolated from the Human Oral Microbiome in an Experimental Rat Model. | Ancuta DL, Alexandru DM, Crivineanu M, Coman C. | Biomedicines | 10.3390/biomedicines11082098 | 2023 | | |
| Intracellular Fusobacterium nucleatum infection increases METTL3-mediated m6A methylation to promote the metastasis of esophageal squamous cell carcinoma. | Guo S, Chen F, Li L, Dou S, Li Q, Huang Y, Li Z, Liu W, Zhang G. | J Adv Res | 10.1016/j.jare.2023.08.014 | 2024 | | |
| Probiotic Species in the Management of Periodontal Diseases: An Overview. | Zhang Y, Ding Y, Guo Q. | Front Cell Infect Microbiol | 10.3389/fcimb.2022.806463 | 2022 | | |
| Natural Compounds in the Battle against Microorganisms-Linalool. | Maczka W, Duda-Madej A, Grabarczyk M, Winska K. | Molecules | 10.3390/molecules27206928 | 2022 | | |
| Amidinoquinoxaline N-oxides: synthesis and activity against anaerobic bacteria. | Gruber N, Fernandez-Canigia L, Kilimciler NB, Stipa P, Bisceglia JA, Garcia MB, Gonzalez Maglio DH, Paz ML, Orelli LR. | RSC Adv | 10.1039/d3ra01184d | 2023 | | |
| Fusobacterium nucleatum Promotes the Progression of Colorectal Cancer Through Cdk5-Activated Wnt/beta-Catenin Signaling. | Li X, Huang J, Yu T, Fang X, Lou L, Xin S, Ji L, Jiang F, Lou Y. | Front Microbiol | 10.3389/fmicb.2020.545251 | 2020 | | |
| Fusobacterium nucleatum-triggered neutrophil extracellular traps facilitate colorectal carcinoma progression. | Kong X, Zhang Y, Xiang L, You Y, Duan Y, Zhao Y, Li S, Wu R, Zhang J, Zhou L, Duan L. | J Exp Clin Cancer Res | 10.1186/s13046-023-02817-8 | 2023 | | |
| Pathogenicity | Periodontitis: etiology, conventional treatments, and emerging bacteriophage and predatory bacteria therapies. | Lasica A, Golec P, Laskus A, Zalewska M, Gedaj M, Popowska M. | Front Microbiol | 10.3389/fmicb.2024.1469414 | 2024 | |
| A distinct Fusobacterium nucleatum clade dominates the colorectal cancer niche. | Zepeda-Rivera M, Minot SS, Bouzek H, Wu H, Blanco-Miguez A, Manghi P, Jones DS, LaCourse KD, Wu Y, McMahon EF, Park SN, Lim YK, Kempchinsky AG, Willis AD, Cotton SL, Yost SC, Sicinska E, Kook JK, Dewhirst FE, Segata N, Bullman S, Johnston CD. | Nature | 10.1038/s41586-024-07182-w | 2024 | | |
| Bovine Milk and Yogurt Affect Oral Microorganisms and Biofilms In-Vitro. | Tennert C, Sarra G, Stahli A, Sculean A, Eick S. | Oral Health Prev Dent | 10.3290/j.ohpd.b3920023 | 2023 | | |
| Keystone pathobionts associated with colorectal cancer promote oncogenic reprograming. | Jones J, Shi Q, Nath RR, Brito IL. | PLoS One | 10.1371/journal.pone.0297897 | 2024 | | |
| The Role of Porphyromonas gingivalis in Oral Carcinogenesis and Progression by Remodelling the Tumour Microenvironment: A Narrative Review. | Starska-Kowarska K. | Cancers (Basel) | 10.3390/cancers17213478 | 2025 | | |
| Fusobacterium nucleatum stimulates cell proliferation and promotes PD-L1 expression via IFIT1-related signal in colorectal cancer. | Gao Y, Zou T, Xu P, Wang Y, Jiang Y, Chen YX, Chen H, Hong J, Fang JY. | Neoplasia | 10.1016/j.neo.2022.100850 | 2023 | | |
| Antimicrobial and Antibiofilm Effect of Brazilian Green Propolis Aqueous Extract against Dental Anaerobic Bacteria. | de Sa Assis MA, de Paula Ramos L, Abu Hasna A, de Queiroz TS, Pereira TC, Nagai de Lima PM, Berretta AA, Marcucci MC, Talge Carvalho CA, de Oliveira LD. | Molecules | 10.3390/molecules27238128 | 2022 | | |
| Deep Ultraviolet Light-Emitting Diode Light Therapy for Fusobacterium nucleatum. | Fukuda S, Ito S, Nishikawa J, Takagi T, Kubota N, Otsuyama KI, Tsuneoka H, Nojima J, Harada K, Mishima K, Suehiro Y, Yamasaki T, Sakaida I. | Microorganisms | 10.3390/microorganisms9020430 | 2021 | | |
| Gut microbial metabolite 4-hydroxybenzeneacetic acid drives colorectal cancer progression via accumulation of immunosuppressive PMN-MDSCs. | Liao Q, Zhou X, Wu L, Yang Y, Zhu X, Liao H, Zhang Y, Lian W, Zhang F, Wang H, Ding Y, Zhao L. | J Clin Invest | 10.1172/jci181243 | 2025 | | |
| Construction and validation of a novel angiogenesis pattern to predict prognosis and immunotherapy efficacy in colorectal cancer. | Li Z, Liu Y, Guo P, Wei Y. | Aging (Albany NY) | 10.18632/aging.205189 | 2023 | | |
| Clinical impact of Fn-induced high expression of KIR2DL1 in CD8 T lymphocytes in oesophageal squamous cell carcinoma. | Wang X, Liu Y, Lu Y, Chen S, Xing Y, Yang H, Wang X, Zhang Y, Pan T, Li J, Wang M, Zhang N, Liang M, Zhou F. | Ann Med | 10.1080/07853890.2021.2016942 | 2022 | | |
| Antimicrobial Action, Genotoxicity, and Morphological Analysis of Three Calcium Silicate-Based Cements. | Abu Hasna A, Theodoro AL, Pereira LM, Ramos LP, Campos TMB, Ala Rachi M, Al-Nahalwi T, de Oliveira LD, Carvalho CAT. | Biomed Res Int | 10.1155/2022/2155226 | 2022 | | |
| Genetics | Chlorhexidine digluconate mouthwash alters the oral microbial composition and affects the prevalence of antimicrobial resistance genes. | Bartsch S, Kohnert E, Kreutz C, Woelber JP, Anderson A, Burkhardt AS, Hellwig E, Buchalla W, Hiller KA, Ratka-Krueger P, Cieplik F, Al-Ahmad A. | Front Microbiol | 10.3389/fmicb.2024.1429692 | 2024 | |
| Synergistic antimicrobial potential of EGCG and fosfomycin against biofilms associated with endodontic infections. | Duque C, Souza ACA, Aida KL, Pereira JA, Caiaffa KS, Santos VRD, Cosme-Silva L, Prakki A. | J Appl Oral Sci | 10.1590/1678-7757-2022-0282 | 2023 | | |
| Subgingival Periopathogens Assessment and Clinical Periodontal Evaluation of Gastric Cancer Patients-A Cross Sectional Pilot Study. | Nicolae FM, Didilescu AC, Surlin P, Ungureanu BS, Surlin VM, Patrascu S, Ramboiu S, Jelihovschi I, Iancu LS, Ghilusi M, Cucu M, Gheonea DI. | Pathogens | 10.3390/pathogens11030360 | 2022 | | |
| Quantification of Fusobacterium nucleatum at Depths of Root Dentinal Tubules in the Tooth Using Real-time Polymerase Chain Reaction: An In Vitro Study. | Ganesh A, Veronica AK, Ashok R, Varadan P, Deivanayagam K. | Cureus | 10.7759/cureus.4711 | 2019 | | |
| Staphylococcus aureus Overcomes Anaerobe-Derived Short-Chain Fatty Acid Stress via FadX and the CodY Regulon. | Fletcher JR, Villareal AR, Penningroth MR, Hunter RC. | J Bacteriol | 10.1128/jb.00064-22 | 2022 | | |
| Porphyromonas gingivalis outer membrane vesicles inhibit the invasion of Fusobacterium nucleatum into oral epithelial cells by downregulating FadA and FomA. | Zhang Z, Liu S, Zhang S, Li Y, Shi X, Liu D, Pan Y. | J Periodontol | 10.1002/jper.21-0144 | 2022 | | |
| Biofilm Formation on the Surfaces of CAD/CAM Dental Polymers. | Vulovic S, Nikolic-Jakoba N, Radunovic M, Petrovic S, Popovac A, Todorovic M, Milic-Lemic A. | Polymers (Basel) | 10.3390/polym15092140 | 2023 | | |
| Fusobacterium nucleatum Causes Microbial Dysbiosis and Exacerbates Visceral Hypersensitivity in a Colonization-Independent Manner. | Gu X, Song LJ, Li LX, Liu T, Zhang MM, Li Z, Wang P, Li M, Zuo XL. | Front Microbiol | 10.3389/fmicb.2020.01281 | 2020 | | |
| Fusobacterium nucleatum Affects Cell Apoptosis by Regulating Intestinal Flora and Metabolites to Promote the Development of Colorectal Cancer. | Yu T, Ji L, Lou L, Ye S, Fang X, Li C, Jiang F, Gao H, Lou Y, Li X. | Front Microbiol | 10.3389/fmicb.2022.841157 | 2022 | | |
| Fusobacterium nucleatum Caused DNA Damage and Promoted Cell Proliferation by the Ku70/p53 Pathway in Oral Cancer Cells. | Geng F, Zhang Y, Lu Z, Zhang S, Pan Y. | DNA Cell Biol | 10.1089/dna.2019.5064 | 2020 | | |
| FadA-positive Fusobacterium nucleatum is prevalent in biopsy specimens of Iranian patients with colorectal cancer. | Kashani N, Bezmin Abadi AT, Rahimi F, Forootan M. | New Microbes New Infect | 10.1016/j.nmni.2020.100651 | 2020 | | |
| Antibacterial Activity of 2-Hydroxyisocaproic Acid (HICA) Against Obligate Anaerobic Bacterial Species Associated With Periodontal Disease. | Sakko M, Rautemaa-Richardson R, Sakko S, Richardson M, Sorsa T. | Microbiol Insights | 10.1177/11786361211050086 | 2021 | | |
| Diagnostic accuracy of Fusobacterium nucleatum IgA and IgG ELISA test in colorectal cancer. | Kurt M, Yumuk Z. | Sci Rep | 10.1038/s41598-021-81171-1 | 2021 | | |
| Fn-OMV potentiates ZBP1-mediated PANoptosis triggered by oncolytic HSV-1 to fuel antitumor immunity. | Wang S, Song A, Xie J, Wang YY, Wang WD, Zhang MJ, Wu ZZ, Yang QC, Li H, Zhang J, Sun ZJ. | Nat Commun | 10.1038/s41467-024-48032-7 | 2024 | | |
| MicroRNA-31 induced by Fusobacterium nucleatum infection promotes colorectal cancer tumorigenesis. | Tang B, Lu X, Tong Y, Feng Y, Mao Y, Dun G, Li J, Xu Q, Tang J, Zhang T, Deng L, He X, Lan Y, Luo H, Zeng L, Xiang Y, Li Q, Zeng D, Mao X. | iScience | 10.1016/j.isci.2023.106770 | 2023 | | |
| Phylogeny | Antibiotic exposure enriches streptococci carrying resistance genes in periodontitis plaque biofilms. | Zhang Q, Zhen M, Wang X, Zhao F, Dong Y, Wang X, Gao S, Wang J, Shi W, Zhang Y. | PeerJ | 10.7717/peerj.18835 | 2025 | |
| Anti-biofilm Activity of Oral Health-care Products Containing Chlorhexidine Digluconate and Citrox. | Jeyakumar J, Sculean A, Eick S. | Oral Health Prev Dent | 10.3290/j.ohpd.a45437 | 2020 | | |
| Metabolism | Expression of the SARS-CoV-2 Receptor ACE2 and Proinflammatory Cytokines Induced by the Periodontopathic Bacterium Fusobacterium nucleatum in Human Respiratory Epithelial Cells. | Takahashi Y, Watanabe N, Kamio N, Yokoe S, Suzuki R, Sato S, Iinuma T, Imai K. | Int J Mol Sci | 10.3390/ijms22031352 | 2021 | |
| Gut bacteria promote proliferation in benign S/RG/C2 colorectal tumour cells, and promote proliferation, migration and invasion in malignant HCT116 cells. | Robson JL, Thorn RMS, Williams AC, Collard TJ, Qualtrough D. | Sci Rep | 10.1038/s41598-023-44130-6 | 2023 | | |
| Substrate Specificity and Allosteric Regulation of a D-Lactate Dehydrogenase from a Unicellular Cyanobacterium are Altered by an Amino Acid Substitution. | Ito S, Takeya M, Osanai T. | Sci Rep | 10.1038/s41598-017-15341-5 | 2017 | | |
| Unveiling the intratumor microbiome in liver cancer: Current insights and prospective applications. | Ke X, Jiang S, Wei Q, Sun M, Sun H, Pang M, Liu M, Sun L, Yang H, Mao Y. | Clin Mol Hepatol | 10.3350/cmh.2024.1039 | 2025 | | |
| Metabolism | Heat-Killed Fusobacterium nucleatum Triggers Varying Heme-Related Inflammatory and Stress Responses Depending on Primary Human Respiratory Epithelial Cell Type. | Koike R, Cueno ME, Nodomi K, Tamura M, Kamio N, Tanaka H, Kotani A, Imai K. | Molecules | 10.3390/molecules25173839 | 2020 | |
| Evaluation of the microbiota-sparing properties of the anti-staphylococcal antibiotic afabicin. | Nowakowska J, Cameron DR, De Martino A, Kuhn J, Le Fresne-Languille S, Leuillet S, Amouzou Y, Wittke F, Carton T, Le Vacon F, Chaves RL, Nicolas-Metral V, Vuagniaux G. | J Antimicrob Chemother | 10.1093/jac/dkad181 | 2023 | | |
| Association of perturbation of oral bacterial with incident of Alzheimer's disease: A pilot study. | Taati Moghadam M, Amirmozafari N, Mojtahedi A, Bakhshayesh B, Shariati A, Shariati A, Masjedian Jazi F. | J Clin Lab Anal | 10.1002/jcla.24483 | 2022 | | |
| Biological and chemical properties of five mineral oxides and of mineral trioxide aggregate repair high plasticity: an in vitro study. | Abu Hasna A, de Paula Ramos L, Campos TMB, de Castro Lopes SLP, Rachi MA, de Oliveira LD, Carvalho CAT. | Sci Rep | 10.1038/s41598-022-17854-0 | 2022 | | |
| Phylogeny | Optimal 16S rRNA gene amplicon sequencing analysis for oral microbiota to avoid the potential bias introduced by trimming length, primer, and database. | Nagai T, Shiba T, Komatsu K, Watanabe T, Nemoto T, Maekawa S, Kobayashi R, Matsumura S, Ohsugi Y, Katagiri S, Takeuchi Y, Iwata T. | Microbiol Spectr | 10.1128/spectrum.03512-23 | 2024 | |
| Direct, Broad-Spectrum Antimicrobial Activity of Ag+-Doped Hydroxyapatite against Fastidious Anaerobic Periodontal and Aerobic Dental Bacteria. | Hu R, Deng L, Hao X, Chen J, Zhou X, Sahai N. | Materials (Basel) | 10.3390/ma17194688 | 2024 | | |
| Association between colorectal cancer and Fusobacterium nucleatum and Bacteroides fragilis bacteria in Iranian patients: a preliminary study. | Shariati A, Shariati A, Razavi S, Ghaznavi-Rad E, Jahanbin B, Akbari A, Norzaee S, Darban-Sarokhalil D. | Infect Agent Cancer | 10.1186/s13027-021-00381-4 | 2021 | | |
| Antimicrobial and Osteogenic Effects of Collagen Membrane Decorated with Chitosan-Nano-Hydroxyapatite. | Lazarevic M, Petrovic S, Pierfelice TV, Ignjatovic N, Piattelli A, Vlajic Tovilovic T, Radunovic M. | Biomolecules | 10.3390/biom13040579 | 2023 | | |
| Metabolism | Lactobacillus rhamnosus attenuates intestinal inflammation induced by Fusobacterium nucleatum infection by restoring the autophagic flux. | Duan C, Tang X, Wang W, Qian W, Fu X, Deng X, Zhou S, Han C, Hou X. | Int J Mol Med | 10.3892/ijmm.2020.4780 | 2021 | |
| Dual-functional probiotic hydrogel with puerarin integration for microbiota-neuroimmune regulation in antibiotic-free periodontitis therapy. | Wang Y, Qu Y, Liu X, Huang J, Mao C, Wang C, Zhu S, Zheng Y, Li Z, Cui Z, Jiang H, Lv Y, Shen J, Wu S. | Bioact Mater | 10.1016/j.bioactmat.2025.07.004 | 2025 | | |
| Anti-Early Stage of Bacterial Recolonization Effect of Curcuma longa Extract as Photodynamic Adjunctive Treatment. | Hormdee D, Rinsathorn W, Puasiri S, Jitprasertwong P. | Int J Dent | 10.1155/2020/8823708 | 2020 | | |
| The In-Vitro Activity of a Cold Atmospheric Plasma Device Utilizing Ambient Air against Bacteria and Biofilms Associated with Periodontal or Peri-Implant Diseases. | Jungbauer G, Favaro L, Muller S, Sculean A, Eick S. | Antibiotics (Basel) | 10.3390/antibiotics11060752 | 2022 | | |
| The gut microbial metabolite formate exacerbates colorectal cancer progression. | Ternes D, Tsenkova M, Pozdeev VI, Meyers M, Koncina E, Atatri S, Schmitz M, Karta J, Schmoetten M, Heinken A, Rodriguez F, Delbrouck C, Gaigneaux A, Ginolhac A, Nguyen TTD, Grandmougin L, Frachet-Bour A, Martin-Gallausiaux C, Pacheco M, Neuberger-Castillo L, Miranda P, Zuegel N, Ferrand JY, Gantenbein M, Sauter T, Slade DJ, Thiele I, Meiser J, Haan S, Wilmes P, Letellier E. | Nat Metab | 10.1038/s42255-022-00558-0 | 2022 | | |
| Siglec-7 Mediates Immunomodulation by Colorectal Cancer-Associated Fusobacterium nucleatum ssp. animalis. | Lamprinaki D, Garcia-Vello P, Marchetti R, Hellmich C, McCord KA, Bowles KM, Macauley MS, Silipo A, De Castro C, Crocker PR, Juge N. | Front Immunol | 10.3389/fimmu.2021.744184 | 2021 | | |
| Streptococcus sobrinus as a Predominant Oral Bacteria Related to the Occurrence of Dental Caries in Polish Children at 12 Years Old. | Korona-Glowniak I, Skawinska-Bednarczyk A, Wrobel R, Pietrak J, Tkacz-Ciebiera I, Maslanko-Switala M, Krawczyk D, Bakiera A, Borek A, Malm A, Mielnik-Blaszczak M. | Int J Environ Res Public Health | 10.3390/ijerph192215005 | 2022 | | |
| Influence of resin modified glass ionomer cement incorporating protein-repellent and antimicrobial agents on supragingival microbiome around brackets: an in-vivo split-mouth 3-month study. | Ma Y, Su C, Yang H, Xu HHK, Bai Y, Xu Y, Che X, Zhang N. | PeerJ | 10.7717/peerj.14820 | 2023 | | |
| Antimicrobial Efficiency of Pistacia lentiscus L. Derivates against Oral Biofilm-Associated Diseases-A Narrative Review. | Milia EP, Sardellitti L, Eick S. | Microorganisms | 10.3390/microorganisms11061378 | 2023 | | |
| Phylogeny | Impact of preoperative antibiotics and other variables on integrated microbiome-host transcriptomic data generated from colorectal cancer resections. | Malik SA, Zhu C, Li J, LaComb JF, Denoya PI, Kravets I, Miller JD, Yang J, Kramer M, McCombie WR, Robertson CE, Frank DN, Li E. | World J Gastroenterol | 10.3748/wjg.v27.i14.1465 | 2021 | |
| Nisin and Nisin Probiotic Disrupt Oral Pathogenic Biofilms and Restore Their Microbiome Composition towards Healthy Control Levels in a Peri-Implantitis Setting. | Radaic A, Brody H, Contreras F, Hajfathalian M, Lucido L, Kamarajan P, Kapila YL. | Microorganisms | 10.3390/microorganisms10071336 | 2022 | | |
| The Bio-Aging of Biofilms on Behalf of Various Oral Status on Different Titanium Implant Materials. | Liao M, Shi Y, Chen E, Shou Y, Dai D, Xian W, Ren B, Xiao S, Cheng L. | Int J Mol Sci | 10.3390/ijms24010332 | 2022 | | |
| Nitroreductase-instructed supramolecular assemblies for microbiome regulation to enhance colorectal cancer treatments. | Chen J, Zhang P, Zhao Y, Zhao J, Wu X, Zhang R, Cha R, Yao Q, Gao Y. | Sci Adv | 10.1126/sciadv.add2789 | 2022 | | |
| Antimicrobial and Anti-inflammatory Lingonberry Mouthwash - A Clinical Pilot Study in the Oral Cavity. | Parnanen P, Nikula-Ijas P, Sorsa T. | Microorganisms | 10.3390/microorganisms7090331 | 2019 | | |
| Study of an arginine- and tryptophan-rich antimicrobial peptide in peri-implantitis. | Zhang Q, Jiang Y, He X, Liu L, Zhang X. | Front Bioeng Biotechnol | 10.3389/fbioe.2024.1486213 | 2024 | | |
| Genetics | Identification and Validation of Potential Candidate Genes of Colorectal Cancer in Response to Fusobacterium nucleatum Infection. | Zhang J, Wang Z, Lv H, Li G. | Front Genet | 10.3389/fgene.2021.690990 | 2021 | |
| Breast cancer colonization by Fusobacterium nucleatum accelerates tumor growth and metastatic progression. | Parhi L, Alon-Maimon T, Sol A, Nejman D, Shhadeh A, Fainsod-Levi T, Yajuk O, Isaacson B, Abed J, Maalouf N, Nissan A, Sandbank J, Yehuda-Shnaidman E, Ponath F, Vogel J, Mandelboim O, Granot Z, Straussman R, Bachrach G. | Nat Commun | 10.1038/s41467-020-16967-2 | 2020 | | |
| Pathogenicity | The dental infections in patients undergoing preoperative dental examination before surgical treatment of saccular intracranial aneurysm. | Pyysalo MJ, Pyysalo LM, Hiltunen J, Jarnstedt J, Helminen M, Karhunen PJ, Pessi T. | BMC Res Notes | 10.1186/s13104-018-3704-z | 2018 | |
| Pathogenicity | The Pathogenic Effects of Fusobacterium nucleatum on the Proliferation, Osteogenic Differentiation, and Transcriptome of Osteoblasts. | Gao H, Sun T, Yang F, Yuan J, Yang M, Kang W, Tang D, Zhang J, Feng Q. | Front Cell Dev Biol | 10.3389/fcell.2020.00807 | 2020 | |
| Structural insight into the high reduction potentials observed for Fusobacterium nucleatum flavodoxin. | Mothersole RG, Macdonald M, Kolesnikov M, Murphy MEP, Wolthers KR. | Protein Sci | 10.1002/pro.3661 | 2019 | | |
| The Potential of Colonic Tumor Tissue Fusobacterium nucleatum to Predict Staging and Its Interplay with Oral Abundance in Colon Cancer Patients. | Pignatelli P, Iezzi L, Pennese M, Raimondi P, Cichella A, Bondi D, Grande R, Cotellese R, Di Bartolomeo N, Innocenti P, Piattelli A, Curia MC. | Cancers (Basel) | 10.3390/cancers13051032 | 2021 | | |
| A Study of Zn-Ca Nanocomposites and Their Antibacterial Properties. | Torres-Ramos MI, Martin-Camacho UJ, Gonzalez JL, Yanez-Acosta MF, Becerra-Solano L, Gutierrez-Mercado YK, Macias-Carballo M, Gomez CM, Gonzalez-Vargas OA, Rivera-Mayorga JA, Perez-Larios A. | Int J Mol Sci | 10.3390/ijms23137258 | 2022 | | |
| Genetics | FusoPortal: an Interactive Repository of Hybrid MinION-Sequenced Fusobacterium Genomes Improves Gene Identification and Characterization. | Sanders BE, Umana A, Lemkul JA, Slade DJ. | mSphere | 10.1128/msphere.00228-18 | 2018 | |
| In Vitro Activity of Propolis on Oral Microorganisms and Biofilms. | Stahli A, Schroter H, Bullitta S, Serralutzu F, Dore A, Nietzsche S, Milia E, Sculean A, Eick S. | Antibiotics (Basel) | 10.3390/antibiotics10091045 | 2021 | | |
| The Antibacterial Potential of Brazilian Red Propolis against the Formation and Eradication of Biofilm of Helicobacter pylori. | Santiago MB, Tanimoto MH, Ambrosio MALV, Veneziani RCS, Bastos JK, Sabino-Silva R, Martins CHG. | Antibiotics (Basel) | 10.3390/antibiotics13080719 | 2024 | | |
| Oral Administration of Lactobacillus acidophilus LA5 Prevents Alveolar Bone Loss and Alters Oral and Gut Microbiomes in a Murine Periodontitis Experimental Model | Cataruci A, Kawamoto D, Shimabukuro N, Ishikawa K, Ando-Suguimoto E, Ribeiro R, Nicastro G, Albuquerque-Souza E, de Souza R, Mayer M. | Microorganisms | 2024 | | ||
| Pathogenicity | A cocoa (Theobroma cacao L.) extract impairs the growth, virulence properties, and inflammatory potential of Fusobacterium nucleatum and improves oral epithelial barrier function. | Ben Lagha A, Maquera Huacho P, Grenier D. | PLoS One | 10.1371/journal.pone.0252029 | 2021 | |
| Antioxidant and Antibacterial Activities of Nano-probiotics Versus Free Probiotics Against Gastrointestinal Pathogenic Bacteria. | Al-Hazmi NE, Naguib DM. | Indian J Microbiol | 10.1007/s12088-023-01140-2 | 2024 | | |
| Fusobacterium nucleatum promotes epithelial-mesenchymal transiton through regulation of the lncRNA MIR4435-2HG/miR-296-5p/Akt2/SNAI1 signaling pathway. | Zhang S, Li C, Liu J, Geng F, Shi X, Li Q, Lu Z, Pan Y. | FEBS J | 10.1111/febs.15233 | 2020 | | |
| Genetics | MinION Sequencing of colorectal cancer tumour microbiomes-A comparison with amplicon-based and RNA-Sequencing. | Taylor WS, Pearson J, Miller A, Schmeier S, Frizelle FA, Purcell RV. | PLoS One | 10.1371/journal.pone.0233170 | 2020 | |
| Metabolism | Fusobacterium nucleatum promotes colorectal cancer metastasis by modulating KRT7-AS/KRT7. | Chen S, Su T, Zhang Y, Lee A, He J, Ge Q, Wang L, Si J, Zhuo W, Wang L. | Gut Microbes | 10.1080/19490976.2019.1695494 | 2020 | |
| Pan-Cancer Analysis of Prognostic and Immune Infiltrates for CXCs. | Li L, Yao W, Yan S, Dong X, Lv Z, Jing Q, Wang Q, Ma B, Hao C, Xue D, Wang D. | Cancers (Basel) | 10.3390/cancers13164153 | 2021 | | |
| Loureirin A is a narrow-spectrum antimicrobial agent against Helicobacter pylori. | Tong Q, Yin C, Hang X, Bai Y, Zhang C, Xu J, Huang Y, Ge Y, Chen T, Zeng L, Jia J, Bi H. | Antimicrob Agents Chemother | 10.1128/aac.00314-24 | 2024 | | |
| Comparison of the Antibacterial Efficacy of Commiphora molmol and Sodium Hypochlorite as Root Canal Irrigants against Enterococcus faecalis and Fusobacterium nucleatum. | Al-Madi EM, Almohaimede AA, Al-Obaida MI, Awaad AS. | Evid Based Complement Alternat Med | 10.1155/2019/6916795 | 2019 | | |
| Tobacco-enhanced biofilm formation by Porphyromonas gingivalis and other oral microbes. | Tan J, Lamont GJ, Scott DA. | Mol Oral Microbiol | 10.1111/omi.12450 | 2024 | | |
| Pathogenicity | Compounds from Olea europaea and Pistacia lentiscus inhibit oral microbial growth. | Karygianni L, Cecere M, Argyropoulou A, Hellwig E, Skaltsounis AL, Wittmer A, Tchorz JP, Al-Ahmad A. | BMC Complement Altern Med | 10.1186/s12906-019-2461-4 | 2019 | |
| Ozone ultrafine bubble water exhibits bactericidal activity against pathogenic bacteria in the oral cavity and upper airway and disinfects contaminated healthcare equipment. | Takizawa F, Domon H, Hiyoshi T, Tamura H, Shimizu K, Maekawa T, Tabeta K, Ushida A, Terao Y. | PLoS One | 10.1371/journal.pone.0284115 | 2023 | | |
| Bactericidal Effect of Different Anti-Microbial Agents on Fusobacterium Nucleatum Biofilm. | Ashok R, Ganesh A, Deivanayagam K. | Cureus | 10.7759/cureus.1335 | 2017 | | |
| Differential involvement of the canonical and noncanonical inflammasomes in the immune response against infection by the periodontal bacteria Porphyromonas gingivalis and Fusobacterium nucleatum. | De Andrade KQ, Almeida-da-Silva CLC, Ojcius DM, Coutinho-Silva R. | Curr Res Microb Sci | 10.1016/j.crmicr.2021.100023 | 2021 | | |
| An In Vitro study to Compare Dental Laser with other Treatment Modalities on Biofilm Ablation from Implant and Tooth Surfaces. | Vaddamanu SK, Vyas R, Kavita K, Sushma R, Rani RP, Dixit A, Badiyani BK. | J Pharm Bioallied Sci | 10.4103/jpbs.jpbs_98_22 | 2022 | | |
| Disinfection and Biocompatibility of Titanium Surfaces Treated with Glycine Powder Airflow and Triple Antibiotic Mixture: An In Vitro Study. | Alovisi M, Carossa M, Mandras N, Roana J, Costalonga M, Cavallo L, Pira E, Putzu MG, Bosio D, Roato I, Mussano F, Scotti N. | Materials (Basel) | 10.3390/ma15144850 | 2022 | | |
| Enzymology | Fusobacterium nucleatum in biopsied tissues from colorectal cancer patients and alcohol consumption in Korea. | Kim M, Lee ST, Choi S, Lee H, Kwon SS, Byun JH, Kim YA, Rhee KJ, Choi JR, Kim TI, Lee K. | Sci Rep | 10.1038/s41598-020-76467-7 | 2020 | |
| Metabolism | Fusobacterium nucleatum promotes colorectal cancer metastasis through miR-1322/CCL20 axis and M2 polarization. | Xu C, Fan L, Lin Y, Shen W, Qi Y, Zhang Y, Chen Z, Wang L, Long Y, Hou T, Si J, Chen S. | Gut Microbes | 10.1080/19490976.2021.1980347 | 2021 | |
| Antimicrobial and Other Biomedical Properties of Extracts from Plantago major, Plantaginaceae. | Zhakipbekov K, Turgumbayeva A, Issayeva R, Kipchakbayeva A, Kadyrbayeva G, Tleubayeva M, Akhayeva T, Tastambek K, Sainova G, Serikbayeva E, Tolenova K, Makhatova B, Anarbayeva R, Shimirova Z, Tileuberdi Y. | Pharmaceuticals (Basel) | 10.3390/ph16081092 | 2023 | | |
| Enterobacterial LPS-inducible LINC00152 is regulated by histone lactylation and promotes cancer cells invasion and migration. | Wang J, Liu Z, Xu Y, Wang Y, Wang F, Zhang Q, Ni C, Zhen Y, Xu R, Liu Q, Fang W, Huang P, Liu X. | Front Cell Infect Microbiol | 10.3389/fcimb.2022.913815 | 2022 | | |
| Metformin abrogates Fusobacterium nucleatum-induced chemoresistance in colorectal cancer by inhibiting miR-361-5p/sonic hedgehog signaling-regulated stemness. | Hong XL, Yu TC, Huang XW, Wang JL, Sun TT, Yan TT, Zhou CB, Chen HM, Su WY, Du W, Xiong H. | Br J Cancer | 10.1038/s41416-022-02044-6 | 2023 | | |
| Identification of Veillonella parvula and Streptococcus gordonii adhesins mediating co-aggregation and its impact on physiology and mixed biofilm structure. | Dorison L, Bechon N, Martin-Gallausiaux C, Chamorro-Rodriguez S, Vitrenko Y, Ouazahrou R, Villa R, Deschamps J, Briandet R, Gribaldo S, Ghigo J-M, Beloin C. | mBio | 10.1128/mbio.02171-24 | 2024 | | |
| Oral Pathogen Fusobacterium nucleatum Coaggregates With Pseudomonas aeruginosa to Modulate the Inflammatory Cytotoxicity of Pulmonary Epithelial Cells. | Li Q, Wang H, Tan L, Zhang S, Lin L, Tang X, Pan Y. | Front Cell Infect Microbiol | 10.3389/fcimb.2021.643913 | 2021 | | |
| Profiling Fusobacterium infection at high taxonomic resolution reveals lineage-specific correlations in colorectal cancer. | Bi D, Zhu Y, Gao Y, Li H, Zhu X, Wei R, Xie R, Cai C, Wei Q, Qin H. | Nat Commun | 10.1038/s41467-022-30957-6 | 2022 | | |
| Pathogenicity | Perillyl alcohol has antibacterial effects and reduces ROS production in macrophages. | Figueiredo RDA, Ortega AC, Gonzalez Maldonado LA, Castro RD, Avila-Campos MJ, Rossa C, Aquino SG. | J Appl Oral Sci | 10.1590/1678-7757-2019-0519 | 2020 | |
| [NLRC4 plays a regulatory role in F. nucleatum-induced pyroptosis in macrophages]. | Jiang W, Deng Z, Zhao W. | Nan Fang Yi Ke Da Xue Xue Bao | 10.12122/j.issn.1673-4254.2022.10.17 | 2022 | | |
| Succession of oral bacterial colonizers on dental implant materials: An in vitro biofilm model. | Siddiqui DA, Fidai AB, Natarajan SG, Rodrigues DC. | Dent Mater | 10.1016/j.dental.2021.12.021 | 2022 | | |
| Comparison of Antibacterial Activities of ProRoot MTA, OrthoMTA, and RetroMTA Against Three Anaerobic Endodontic Bacteria. | Khedmat S, Aminipor M, Pourhajibagher M, Kharazifar MJ, Bahador A. | J Dent (Tehran) | 2018 | | ||
| Activity of five antimicrobial peptides against periodontal as well as non-periodontal pathogenic strains. | Enigk K, Jentsch H, Rodloff AC, Eschrich K, Stingu CS. | J Oral Microbiol | 10.1080/20002297.2020.1829405 | 2020 | | |
| Injectable thermosensitive antibiotic-laden chitosan hydrogel for regenerative endodontics. | Reis-Prado AHD, Rahimnejad M, Dal-Fabbro R, Toledo PTA, Anselmi C, Oliveira PHC, Fenno JC, Cintra LTA, Benetti F, Bottino MC. | Bioact Mater | 10.1016/j.bioactmat.2024.12.026 | 2025 | | |
| The Effects of Antimicrobial Peptide Nal-P-113 on Inhibiting Periodontal Pathogens and Improving Periodontal Status. | Wang H, Ai L, Zhang Y, Cheng J, Yu H, Li C, Zhang D, Pan Y, Lin L. | Biomed Res Int | 10.1155/2018/1805793 | 2018 | | |
| Porphyromonas gingivalis Tyrosine Kinase Is a Fitness Determinant in Polymicrobial Infections. | Perpich JD, Yakoumatos L, Stocke KS, Lewin GR, Ramos A, Yoder-Himes DR, Whiteley M, Lamont RJ. | Infect Immun | 10.1128/iai.00170-22 | 2022 | | |
| Gelatin methacryloyl hydrogel as an injectable scaffold with multi-therapeutic effects to promote antimicrobial disinfection and angiogenesis for regenerative endodontics. | Dubey N, Ribeiro JS, Zhang Z, Xu J, Ferreira JA, Qu L, Mei L, Fenno JC, Schwendeman A, Schwendeman SP, Nor JE, Bottino MC. | J Mater Chem B | 10.1039/d2tb02788g | 2023 | | |
| Eubacterium rectale contributes to colorectal cancer initiation via promoting colitis. | Wang Y, Wan X, Wu X, Zhang C, Liu J, Hou S. | Gut Pathog | 10.1186/s13099-020-00396-z | 2021 | | |
| Metabolism | The proteins of Fusobacterium spp. involved in hydrogen sulfide production from L-cysteine. | Basic A, Blomqvist M, Dahlen G, Svensater G. | BMC Microbiol | 10.1186/s12866-017-0967-9 | 2017 | |
| Systematic Review of Zinc's Benefits and Biological Effects on Oral Health. | Caruso S, Valenti C, Marinucci L, Di Pasquale F, Truppa C, Di Benedetto G, Caruso S, Pagano S. | Materials (Basel) | 10.3390/ma17040800 | 2024 | | |
| Oral commensal bacteria differentially modulate epithelial cell death. | White T, Alimova Y, Alves VTE, Emecen-Huja P, Al-Sabbagh M, Villasante A, Ebersole JL, Gonzalez OA. | Arch Oral Biol | 10.1016/j.archoralbio.2020.104926 | 2020 | | |
| Interaction of periodontitis and orthodontic tooth movement-an in vitro and in vivo study. | Rath-Deschner B, Nogueira AVB, Beisel-Memmert S, Nokhbehsaim M, Eick S, Cirelli JA, Deschner J, Jager A, Damanaki A. | Clin Oral Investig | 10.1007/s00784-021-03988-4 | 2022 | | |
| Comparative Metatranscriptomics of Periodontitis Supports a Common Polymicrobial Shift in Metabolic Function and Identifies Novel Putative Disease-Associated ncRNAs. | Ram-Mohan N, Meyer MM. | Front Microbiol | 10.3389/fmicb.2020.00482 | 2020 | | |
| Application of a modified multifunctional short peptide in the treatment of periodontitis. | Zhang X, Song M, Wang H, Zhang Q, Liu Z, Deng J. | Sci Rep | 10.1038/s41598-024-69933-z | 2024 | | |
| Proteomics of Fusobacterium nucleatum within a model developing oral microbial community. | Hendrickson EL, Wang T, Beck DA, Dickinson BC, Wright CJ, J Lamont R, Hackett M. | Microbiologyopen | 10.1002/mbo3.204 | 2014 | | |
| Effects of Osmotic Stress and Sodium Hypochlorite on Endodontic Microbiota: An In-Vitro Study. | Naicker D, Zilm P, Nagendrababu V, Rossi-Fedele G. | Eur Endod J | 10.14744/eej.2020.70883 | 2020 | | |
| hTAS2R38 polymorphisms modulate oral microbiota and influence the prevalence and treatment outcome of halitosis. | Mei H, Qi C, Liu J, Yang S, Zhou J, Lu Y, Zheng L, Li J, Zhao L, Xu X. | Microbiome | 10.1186/s40168-025-02087-w | 2025 | | |
| Cuprorivaite/hardystonite/alginate composite hydrogel with thermionic effect for the treatment of peri-implant lesion. | Xia Y, Zhang Z, Zhou K, Lin Z, Shu R, Xu Y, Zeng Z, Chang J, Xie Y. | Regen Biomater | 10.1093/rb/rbae028 | 2024 | | |
| Pathogenicity | An Ayurvedic herbal extract inhibits oral epithelial cell IL-8 responses to host and bacterial agonists. | Chang AM, Bamashmous S, Darveau RP, Rajapakse S. | BMC Complement Med Ther | 10.1186/s12906-020-2850-8 | 2020 | |
| Characterization of extracellular polymeric matrix, and treatment of Fusobacterium nucleatum and Porphyromonas gingivalis biofilms with DNase I and proteinase K. | Ali Mohammed MM, Nerland AH, Al-Haroni M, Bakken V. | J Oral Microbiol | 10.3402/jom.v5i0.20015 | 2013 | | |
| Data-driven prediction of colonization outcomes for complex microbial communities. | Wu L, Wang XW, Tao Z, Wang T, Zuo W, Zeng Y, Liu YY, Dai L. | Nat Commun | 10.1038/s41467-024-46766-y | 2024 | | |
| Origanum vulgare ethanolic extracts as a promising source of compounds with antimicrobial, anti-biofilm, and anti-virulence activity against dental plaque bacteria. | Idir F, Van Ginneken S, Coppola GA, Grenier D, Steenackers HP, Bendali F. | Front Microbiol | 10.3389/fmicb.2022.999839 | 2022 | | |
| Genetic and molecular determinants of polymicrobial interactions in Fusobacterium nucleatum. | Wu C, Chen YW, Scheible M, Chang C, Wittchen M, Lee JH, Luong TT, Tiner BL, Tauch A, Das A, Ton-That H. | Proc Natl Acad Sci U S A | 10.1073/pnas.2006482118 | 2021 | | |
| Fusobacterium nucleatum enhances the efficacy of PD-L1 blockade in colorectal cancer. | Gao Y, Bi D, Xie R, Li M, Guo J, Liu H, Guo X, Fang J, Ding T, Zhu H, Cao Y, Xing M, Zheng J, Xu Q, Xu Q, Wei Q, Qin H. | Signal Transduct Target Ther | 10.1038/s41392-021-00795-x | 2021 | | |
| Fusobacterium nucleatum promotes the progression of colorectal cancer by interacting with E-cadherin. | Ma CT, Luo HS, Gao F, Tang QC, Chen W. | Oncol Lett | 10.3892/ol.2018.8947 | 2018 | | |
| The Proteome of Community Living Candida albicans Is Differentially Modulated by the Morphologic and Structural Features of the Bacterial Cohabitants. | Truong T, Pang LM, Rajan S, Wong SSW, Fung YME, Samaranayake L, Seneviratne CJ. | Microorganisms | 10.3390/microorganisms8101541 | 2020 | | |
| Advances in modeling periodontal host-microbe interactions: insights from organotypic and organ-on-chip systems. | Makkar H, Sriram G. | Lab Chip | 10.1039/d4lc00871e | 2025 | | |
| Serine/Glycine Lipid Recovery in Lipid Extracts From Healthy and Diseased Dental Samples: Relationship to Chronic Periodontitis. | Nichols FC, Bhuse K, Clark RB, Provatas AA, Carrington E, Wang YH, Zhu Q, Davey ME, Dewhirst FE. | Front Oral Health | 10.3389/froh.2021.698481 | 2021 | | |
| Metabolism | Regulation of Anti-Apoptotic SOD2 and BIRC3 in Periodontal Cells and Tissues. | Rath-Deschner B, Nogueira AVB, Memmert S, Nokhbehsaim M, Augusto Cirelli J, Eick S, Miosge N, Kirschneck C, Kesting M, Deschner J, Jager A, Damanaki A. | Int J Mol Sci | 10.3390/ijms22020591 | 2021 | |
| Pathogenicity | Mediterranean herb extracts inhibit microbial growth of representative oral microorganisms and biofilm formation of Streptococcus mutans. | Hickl J, Argyropoulou A, Sakavitsi ME, Halabalaki M, Al-Ahmad A, Hellwig E, Aligiannis N, Skaltsounis AL, Wittmer A, Vach K, Karygianni L. | PLoS One | 10.1371/journal.pone.0207574 | 2018 | |
| Gut Bacteria-derived Membrane Vesicles Induce Colonic Dysplasia by Inducing DNA Damage in Colon Epithelial Cells. | Miyakawa Y, Otsuka M, Shibata C, Seimiya T, Yamamoto K, Ishibashi R, Kishikawa T, Tanaka E, Isagawa T, Takeda N, Kamio N, Imai K, Fujishiro M. | Cell Mol Gastroenterol Hepatol | 10.1016/j.jcmgh.2024.01.010 | 2024 | | |
| Safe-by-Design Antibacterial Peroxide-Substituted Biomimetic Apatites: Proof of Concept in Tropical Dentistry. | Ana ID, Lestari A, Lagarrigue P, Soulie J, Anggraeni R, Maube-Bosc F, Thouron C, Duployer B, Tenailleau C, Drouet C. | J Funct Biomater | 10.3390/jfb13030144 | 2022 | | |
| Immunomodulation Mediated by Azithromycin in Experimental Periapical Inflammation. | Andrada AC, Azuma MM, Furusho H, Hirai K, Xu S, White RR, Sasaki H. | J Endod | 10.1016/j.joen.2020.07.028 | 2020 | | |
| Enzymology | Crystal structures and kinetic analyses of N-acetylmannosamine-6-phosphate 2-epimerases from Fusobacterium nucleatum and Vibrio cholerae. | Manjunath L, Guntupalli SR, Currie MJ, North RA, Dobson RCJ, Nayak V, Subramanian R. | Acta Crystallogr F Struct Biol Commun | 10.1107/s2053230x18008543 | 2018 | |
| Identification and characterization of non-coding RNA networks in infected macrophages revealing the pathogenesis of F. nucleatum-associated diseases. | Zhou J, Liu L, Wu P, Zhao L, Wu Y. | BMC Genomics | 10.1186/s12864-022-09052-z | 2022 | | |
| The role of Fusobacterium nucleatum in colorectal cancer: from carcinogenesis to clinical management. | Sun CH, Li BB, Wang B, Zhao J, Zhang XY, Li TT, Li WB, Tang D, Qiu MJ, Wang XC, Zhu CM, Qian ZR. | Chronic Dis Transl Med | 10.1016/j.cdtm.2019.09.001 | 2019 | | |
| In vitro activity of hyaluronic acid and human serum on periodontal biofilm and periodontal ligament fibroblasts. | Zhu X, von Werdt L, Zappala G, Sculean A, Eick S, Stahli A. | Clin Oral Investig | 10.1007/s00784-023-05121-z | 2023 | | |
| Phylogeny | Fusobacterium nucleatum subspecies identification by matrix-assisted laser desorption ionization-time of flight mass spectrometry. | Nie S, Tian B, Wang X, Pincus DH, Welker M, Gilhuley K, Lu X, Han YW, Tang YW. | J Clin Microbiol | 10.1128/jcm.00239-15 | 2015 | |
| Insights into the Phytochemical and Multifunctional Biological Profile of Spices from the Genus Piper. | Luca SV, Gawel-Beben K, Strzepek-Gomolka M, Czech K, Trifan A, Zengin G, Korona-Glowniak I, Minceva M, Gertsch J, Skalicka-Wozniak K. | Antioxidants (Basel) | 10.3390/antiox10101642 | 2021 | | |
| Enzymology | Crystal structures and kinetics of N-acetylneuraminate lyase from Fusobacterium nucleatum. | Kumar JP, Rao H, Nayak V, Ramaswamy S. | Acta Crystallogr F Struct Biol Commun | 10.1107/s2053230x18012992 | 2018 | |
| Oral Microbiota-Driven Cell Migration in Carcinogenesis and Metastasis. | Bai H, Yang J, Meng S, Liu C. | Front Cell Infect Microbiol | 10.3389/fcimb.2022.864479 | 2022 | | |
| Draft Genome Sequence of Fusobacterium nucleatum subsp. nucleatum ChDC F316, Isolated from a Human Peri-implantitis Lesion in the Republic of Korea. | Park SN, Cho E, Kim HS, Kim DS, Jung J, Baek JH, Kyong Lim Y, Jo E, Chang YH, Hwan Shin J, Choi SH, Kang J, Choi Y, Park HS, Kim H, Kook JK. | Genome Announc | 10.1128/genomea.01041-13 | 2013 | | |
| Pathogenicity | Ta-Coated Titanium Surface With Superior Bacteriostasis And Osseointegration. | Zhang XM, Li Y, Gu YX, Zhang CN, Lai HC, Shi JY. | Int J Nanomedicine | 10.2147/ijn.s218640 | 2019 | |
| Evaluation of Predation Capability of Periodontopathogens Bacteria by Bdellovibrio Bacteriovorus HD100. An in Vitro Study. | Patini R, Cattani P, Marchetti S, Isola G, Quaranta G, Gallenzi P. | Materials (Basel) | 10.3390/ma12122008 | 2019 | | |
| Mouthwash Effects on LGG-Integrated Experimental Oral Biofilms. | Jiang Q, Kainulainen V, Stamatova I, Janket SJ, Meurman JH, Korpela R. | Dent J (Basel) | 10.3390/dj8030096 | 2020 | | |
| Conceptual Perspectives: Bacterial Antimicrobial Peptide Induction as a Novel Strategy for Symbiosis with the Human Host. | Ghosh SK, Feng Z, Fujioka H, Lux R, McCormick TS, Weinberg A. | Front Microbiol | 10.3389/fmicb.2018.00302 | 2018 | | |
| Influence of oral bacteria on adhesion of Streptococcus mutans and Streptococcus sanguinis to dental materials. | Nabert-Georgi C, Rodloff AC, Jentsch H, Reissmann DR, Schaumann R, Stingu CS. | Clin Exp Dent Res | 10.1002/cre2.107 | 2018 | | |
| Periodontal Treatment During the Blanking Period Improves the Outcome of Atrial Fibrillation Ablation. | Miyauchi S, Ouhara K, Shintani T, Tokuyama T, Okubo Y, Okamura S, Miyamoto S, Oguri N, Uotani Y, Takemura T, Tari M, Hiyama T, Miyauchi M, Kajiya M, Mizuno N, Nakano Y. | J Am Heart Assoc | 10.1161/jaha.123.033740 | 2024 | | |
| Fap2 of Fusobacterium nucleatum is a galactose-inhibitable adhesin involved in coaggregation, cell adhesion, and preterm birth. | Coppenhagen-Glazer S, Sol A, Abed J, Naor R, Zhang X, Han YW, Bachrach G. | Infect Immun | 10.1128/iai.02838-14 | 2015 | | |
| Antibacterial and Anti-Inflammatory Properties of Peptide KN-17. | Zhang Q, Yu S, Hu M, Liu Z, Yu P, Li C, Zhang X. | Microorganisms | 10.3390/microorganisms10112114 | 2022 | | |
| Enzymology | Confocal Raman microscopy to identify bacteria in oral subgingival biofilm models. | Kriem LS, Wright K, Ccahuana-Vasquez RA, Rupp S. | PLoS One | 10.1371/journal.pone.0232912 | 2020 | |
| Bioinspired hydrogel for sustained minocycline release: A superior periodontitis solution. | Liu S, Zheng W, Wang L, Zhang Y, Feng K, Zhang Y, Yang H, Xiao Y, Sun C, Liu X, Lu B, Yin X. | Mater Today Bio | 10.1016/j.mtbio.2025.101638 | 2025 | | |
| Metabolism | Colorectal cancer-associated anaerobic bacteria proliferate in tumor spheroids and alter the microenvironment. | Kasper SH, Morell-Perez C, Wyche TP, Sana TR, Lieberman LA, Hett EC. | Sci Rep | 10.1038/s41598-020-62139-z | 2020 | |
| Antimicrobial FiteBac® K21 promotes antimicrobial Potency and wound healing. | Bapat RA, Libat R, Yuin OS, Parolia A, Ilyas MS, Khan AS, Kay MK, Pichika MR, Saxena K, Seow LL, Sidhu P, Daood U. | Heliyon | 10.1016/j.heliyon.2023.e19282 | 2023 | | |
| Correlation between the Antimicrobial Activity and Metabolic Profiles of Cell Free Supernatants and Membrane Vesicles Produced by Lactobacillus reuteri DSM 17938. | Maccelli A, Carradori S, Puca V, Sisto F, Lanuti P, Crestoni ME, Lasalvia A, Muraro R, Bysell H, Di Sotto A, Roos S, Grande R. | Microorganisms | 10.3390/microorganisms8111653 | 2020 | | |
| The effect of metronidazole plus amoxicillin or metronidazole plus penicillin V on periodontal pathogens in an in vitro biofilm model. | Dabija-Wolter G, Al-Zubaydi SS, Mohammed MMA, Bakken V, Bolstad AI. | Clin Exp Dent Res | 10.1002/cre2.96 | 2018 | | |
| Synthesis and Characterization of Bioactive Glass and Zinc Oxide Nanoparticles with Enamel Remineralization and Antimicrobial Capabilities. | Nagasaki R, Nagano K, Nezu T, Iijima M. | Materials (Basel) | 10.3390/ma16216878 | 2023 | | |
| Regulation of tryptophan-indole metabolic pathway in Porphyromonas gingivalis virulence and microbiota dysbiosis in periodontitis. | Ding J, Tan L, Wu L, Li J, Zhang Y, Shen Z, Zhang C, Zhao C, Gao L. | NPJ Biofilms Microbiomes | 10.1038/s41522-025-00669-y | 2025 | | |
| Transcriptome | Characterization of Fusobacterium varium Fv113-g1 isolated from a patient with ulcerative colitis based on complete genome sequence and transcriptome analysis. | Sekizuka T, Ogasawara Y, Ohkusa T, Kuroda M. | PLoS One | 10.1371/journal.pone.0189319 | 2017 | |
| Enzymology | Effects of statins on multispecies oral biofilm identify simvastatin as a drug candidate targeting Porphyromonas gingivalis. | Kaminska M, Aliko A, Hellvard A, Bielecka E, Binder V, Marczyk A, Potempa J, Delaleu N, Kantyka T, Mydel P. | J Periodontol | 10.1002/jper.18-0179 | 2019 | |
| Pathogenicity | Diaminopimelic acid (DAP) analogs bearing isoxazoline moiety as selective inhibitors against meso-diaminopimelate dehydrogenase (m-Ddh) from Porphyromonas gingivalis. | Ma H, Stone VN, Wang H, Kellogg GE, Xu P, Zhang Y. | Bioorg Med Chem Lett | 10.1016/j.bmcl.2017.06.056 | 2017 | |
| Differential immune responses of 3D gingival and periodontal connective tissue equivalents to microbial colonization. | Makkar H, Atkuru S, Tang YL, Sethi T, Lim CT, Tan KS, Sriram G. | J Tissue Eng | 10.1177/20417314221111650 | 2022 | | |
| Pathogenicity | The DNA Glycosylase NEIL2 Suppresses Fusobacterium-Infection-Induced Inflammation and DNA Damage in Colonic Epithelial Cells. | Sayed IM, Chakraborty A, Abd El-Hafeez AA, Sharma A, Sahan AZ, Huang WJM, Sahoo D, Ghosh P, Hazra TK, Das S. | Cells | 10.3390/cells9091980 | 2020 | |
| Enzymology | Perturbed human sub-networks by Fusobacterium nucleatum candidate virulence proteins. | Zanzoni A, Spinelli L, Braham S, Brun C. | Microbiome | 10.1186/s40168-017-0307-1 | 2017 | |
| Activatable prodrug for controlled release of an antimicrobial peptide via the proteases overexpressed in Candida albicans and Porphyromonas gingivalis. | Amer L, Retout M, Jokerst JV. | Theranostics | 10.7150/thno.91165 | 2024 | | |
| Metabolism | Identification and characterization of a novel Fusobacterium nucleatum adhesin involved in physical interaction and biofilm formation with Streptococcus gordonii. | Lima BP, Shi W, Lux R. | Microbiologyopen | 10.1002/mbo3.444 | 2017 | |
| Metabolism | Persistent Exposure to Fusobacterium nucleatum Triggers Chemokine/Cytokine Release and Inhibits the Proliferation and Osteogenic Differentiation Capabilities of Human Gingiva-Derived Mesenchymal Stem Cells. | Kang W, Ji X, Zhang X, Tang D, Feng Q. | Front Cell Infect Microbiol | 10.3389/fcimb.2019.00429 | 2019 | |
| Metabolism | Fusobacterium nucleatum host-cell binding and invasion induces IL-8 and CXCL1 secretion that drives colorectal cancer cell migration. | Casasanta MA, Yoo CC, Udayasuryan B, Sanders BE, Umana A, Zhang Y, Peng H, Duncan AJ, Wang Y, Li L, Verbridge SS, Slade DJ. | Sci Signal | 10.1126/scisignal.aba9157 | 2020 | |
| A comparative antimicrobial analysis of various root canal irrigating solutions on endodontic pathogens: an in vitro study. | Misuriya A, Bhardwaj A, Bhardwaj A, Aggrawal S, Kumar PP, Gajjarepu S. | J Contemp Dent Pract | 10.5005/jp-journals-10024-1506 | 2014 | | |
| Genetics | Clusters of hairpins induce intrinsic transcription termination in bacteria. | Gupta S, Pal D. | Sci Rep | 10.1038/s41598-021-95435-3 | 2021 | |
| Transcriptome | Intrahepatic Microbial Heterogeneity in Multifocal Hepatocellular Carcinoma and Its Association with Host Genomic and Transcriptomic Alterations. | Lu Y, Xu L, Chen W, Liu W, Zhang Y, Zhou Q, Wang N, Zhang Y, Bai H, Xu S, Huang P, Fu K, Xie W, Liu X, Wang X, Wong CC, Kuang M, Yu J. | Cancer Discov | 10.1158/2159-8290.cd-24-1259 | 2025 | |
| Enzymology | Feasibility of investigating the association between bacterial pathogens and oral leukoplakia in low and middle income countries: A population-based pilot study in India. | Shridhar K, Aggarwal A, Rawal I, Gupta R, Masih S, Mehrotra R, Gillespie TW, Dhillon PK, Michaud DS, Prabhakaran D, Goodman M. | PLoS One | 10.1371/journal.pone.0251017 | 2021 | |
| Enzymology | Evaluation of Liquid-Based Swab Transport Systems against the New Approved CLSI M40-A2 Standard. | Gizzie N, Adukwu E. | J Clin Microbiol | 10.1128/jcm.03337-15 | 2016 | |
| Pathogenicity | Hypoxia-induced endothelial cell responses - possible roles during periodontal disease. | Mendes RT, Nguyen D, Stephens D, Pamuk F, Fernandes D, Hasturk H, Van Dyke TE, Kantarci A. | Clin Exp Dent Res | 10.1002/cre2.135 | 2018 | |
| Periodontitis salivary microbiota exacerbates colitis-induced anxiety-like behavior via gut microbiota. | Qian J, Lu J, Cheng S, Zou X, Tao Q, Wang M, Wang N, Zheng L, Liao W, Li Y, Yan F. | NPJ Biofilms Microbiomes | 10.1038/s41522-023-00462-9 | 2023 | | |
| Metabolism | Metformin elicits antitumour effect by modulation of the gut microbiota and rescues Fusobacterium nucleatum-induced colorectal tumourigenesis. | Huang X, Hong X, Wang J, Sun T, Yu T, Yu Y, Fang J, Xiong H. | EBioMedicine | 10.1016/j.ebiom.2020.103037 | 2020 | |
| Periodontal Pathogens Promote Oral Squamous Cell Carcinoma by Regulating ATR and NLRP3 Inflammasome. | Yao Y, Shen X, Zhou M, Tang B. | Front Oncol | 10.3389/fonc.2021.722797 | 2021 | | |
| Transcriptome | Time-Course Transcriptome Analysis for Drug Repositioning in Fusobacterium nucleatum-Infected Human Gingival Fibroblasts. | Kang W, Jia Z, Tang D, Zhao X, Shi J, Jia Q, He K, Feng Q. | Front Cell Dev Biol | 10.3389/fcell.2019.00204 | 2019 | |
| Pharmacological and analytical aspects of alkannin/shikonin and their derivatives: An update from 2008 to 2022. | Kaur K, Sharma R, Singh A, Attri S, Arora S, Kaur S, Bedi N. | Chin Herb Med | 10.1016/j.chmed.2022.08.001 | 2022 | | |
| Anti-Inflammatory and Anti-Bacterial Potential of Mulberry Leaf Extract on Oral Microorganisms. | Kim D, Kang KH. | Int J Environ Res Public Health | 10.3390/ijerph19094984 | 2022 | | |
| Pterostilbene complexed with cyclodextrin exerts antimicrobial and anti-inflammatory effects. | Lim YRI, Preshaw PM, Lim LP, Ong MMA, Lin HS, Tan KS. | Sci Rep | 10.1038/s41598-020-66031-8 | 2020 | | |
| Enzymology | Unculturable and culturable periodontal-related bacteria are associated with periodontal inflammation during pregnancy and with preterm low birth weight delivery. | Ye C, Xia Z, Tang J, Khemwong T, Kapila Y, Kuraji R, Huang P, Wu Y, Kobayashi H. | Sci Rep | 10.1038/s41598-020-72807-9 | 2020 | |
| Pathogenicity | In-vitro effects of different hyaluronic acids on periodontal biofilm-immune cell interaction. | Zhu X, Sculean A, Eick S. | Front Cell Infect Microbiol | 10.3389/fcimb.2024.1414861 | 2024 | |
| Pathogenicity | Oral infection of mice with Fusobacterium nucleatum results in macrophage recruitment to the dental pulp and bone resorption. | Johnson L, Almeida-da-Silva CLC, Takiya CM, Figliuolo V, Rocha GM, Weissmuller G, Scharfstein J, Coutinho-Silva R, Ojcius DM. | Biomed J | 10.1016/j.bj.2018.05.001 | 2018 | |
| TLR2/TLR4 activation induces Tregs and suppresses intestinal inflammation caused by Fusobacterium nucleatum in vivo. | Jia YP, Wang K, Zhang ZJ, Tong YN, Han D, Hu CY, Li Q, Xiang Y, Mao XH, Tang B. | PLoS One | 10.1371/journal.pone.0186179 | 2017 | | |
| Multiplex real-time PCR detection and relative quantification of periodontal pathogens. | Coffey J, Choudhry M, Shlossman M, Makin IRS, Singh VK. | Clin Exp Dent Res | 10.1002/cre2.37 | 2016 | | |
| Pathogenicity | Fusobacterium nucleatum promotes chemoresistance to 5-fluorouracil by upregulation of BIRC3 expression in colorectal cancer. | Zhang S, Yang Y, Weng W, Guo B, Cai G, Ma Y, Cai S. | J Exp Clin Cancer Res | 10.1186/s13046-018-0985-y | 2019 | |
| Transcriptome | Gene expression of bacterial collagenolytic proteases in root caries. | Dame-Teixeira N, Parolo CCF, Maltz M, Rup AG, Devine DA, Do T. | J Oral Microbiol | 10.1080/20002297.2018.1424475 | 2018 | |
| Fusobacterium nucleatum biofilm induces epithelial migration in an organotypic model of dento-gingival junction. | Pollanen MT, Gursoy UK, Kononen E, Uitto VJ. | J Periodontol | 10.1902/jop.2012.110535 | 2012 | | |
| Rapid synthesis of bismuth-organic frameworks as selective antimicrobial materials against microbial biofilms. | Huang R, Zhou Z, Lan X, Tang FK, Cheng T, Sun H, Cham-Fai Leung K, Li X, Jin L. | Mater Today Bio | 10.1016/j.mtbio.2022.100507 | 2023 | | |
| Anaerobic co-culture of mesenchymal stem cells and anaerobic pathogens - a new in vitro model system. | Kriebel K, Biedermann A, Kreikemeyer B, Lang H. | PLoS One | 10.1371/journal.pone.0078226 | 2013 | | |
| Pathogenicity | Periodontal pathogens promote cancer aggressivity via TLR/MyD88 triggered activation of Integrin/FAK signaling that is therapeutically reversible by a probiotic bacteriocin. | Kamarajan P, Ateia I, Shin JM, Fenno JC, Le C, Zhan L, Chang A, Darveau R, Kapila YL. | PLoS Pathog | 10.1371/journal.ppat.1008881 | 2020 | |
| High-level antimicrobial efficacy of representative Mediterranean natural plant extracts against oral microorganisms. | Karygianni L, Cecere M, Skaltsounis AL, Argyropoulou A, Hellwig E, Aligiannis N, Wittmer A, Al-Ahmad A. | Biomed Res Int | 10.1155/2014/839019 | 2014 | | |
| Pathogenicity | Fusobacterium spp. target human CEACAM1 via the trimeric autotransporter adhesin CbpF. | Brewer ML, Dymock D, Brady RL, Singer BB, Virji M, Hill DJ. | J Oral Microbiol | 10.1080/20002297.2018.1565043 | 2019 | |
| Metabolism | ANGPTL4-Mediated Promotion of Glycolysis Facilitates the Colonization of Fusobacterium nucleatum in Colorectal Cancer. | Zheng X, Liu R, Zhou C, Yu H, Luo W, Zhu J, Liu J, Zhang Z, Xie N, Peng X, Xu X, Cheng L, Yuan Q, Huang C, Zhou X. | Cancer Res | 10.1158/0008-5472.can-21-2273 | 2021 | |
| Nigella sativa and Thymoquinone: A Natural Blessing for Periodontal Therapy. | Mekhemar M, Hassan Y, Dorfer C. | Antioxidants (Basel) | 10.3390/antiox9121260 | 2020 | | |
| Metabolism | Osteocytes play an important role in experimental periodontitis in healthy and diabetic mice through expression of RANKL. | Graves DT, Alshabab A, Albiero ML, Mattos M, Correa JD, Chen S, Yang Y. | J Clin Periodontol | 10.1111/jcpe.12851 | 2018 | |
| Localization and density of Porphyromonas gingivalis and Tannerella forsythia in gingival and subgingival granulation tissues affected by chronic or aggressive periodontitis. | Rajakaruna GA, Negi M, Uchida K, Sekine M, Furukawa A, Ito T, Kobayashi D, Suzuki Y, Akashi T, Umeda M, Meinzer W, Izumi Y, Eishi Y. | Sci Rep | 10.1038/s41598-018-27766-7 | 2018 | | |
| Determination of antibacterial activity of green coffee bean extract on periodontogenic bacteria like Porphyromonas gingivalis, Prevotella intermedia, Fusobacterium nucleatum and Aggregatibacter actinomycetemcomitans: An in vitro study. | Bharath N, Sowmya NK, Mehta DS. | Contemp Clin Dent | 10.4103/0976-237x.156036 | 2015 | | |
| Genetics | Comparative Genome Analysis of Fusobacterium nucleatum. | Ang MY, Dutta A, Wee WY, Dymock D, Paterson IC, Choo SW. | Genome Biol Evol | 10.1093/gbe/evw199 | 2016 | |
| Hidden noise in immunologic parameters might explain rapid progression in early-onset periodontitis. | Papantonopoulos G, Delatola C, Takahashi K, Laine ML, Loos BG. | PLoS One | 10.1371/journal.pone.0224615 | 2019 | | |
| Characterization of aid1, a novel gene involved in Fusobacterium nucleatum interspecies interactions. | Kaplan A, Kaplan CW, He X, McHardy I, Shi W, Lux R. | Microb Ecol | 10.1007/s00248-014-0400-y | 2014 | | |
| Characterization of Fusobacterium nucleatum ATCC 23726 adhesins involved in strain-specific attachment to Porphyromonas gingivalis | Park J, Shokeen B, Haake S, Lux R. | International journal of oral science | 10.1038/ijos.2016.27 | 2016 | | |
| Three-Dimensional In Vitro Oral Mucosa Models of Fungal and Bacterial Infections. | Tabatabaei F, Moharamzadeh K, Tayebi L. | Tissue Eng Part B Rev | 10.1089/ten.teb.2020.0016 | 2020 | | |
| Pyroptosis-Related Signature as Potential Biomarkers for Predicting Prognosis and Therapy Response in Colorectal Cancer Patients. | Li Z, Liu Y, Lin B, Yan W, Yi H, Wang H, Wei Y. | Front Genet | 10.3389/fgene.2022.925338 | 2022 | | |
| Pathogenicity | The in Vitro Antimicrobial Efficacy of PDT against Periodontopathogenic Bacteria. | Haag PA, Steiger-Ronay V, Schmidlin PR. | Int J Mol Sci | 10.3390/ijms161126027 | 2015 | |
| Metabolism | Fusobacterium nucleatum promotes colorectal cancer by inducing Wnt/beta-catenin modulator Annexin A1. | Rubinstein MR, Baik JE, Lagana SM, Han RP, Raab WJ, Sahoo D, Dalerba P, Wang TC, Han YW. | EMBO Rep | 10.15252/embr.201847638 | 2019 | |
| Porphyromonas gingivalis suppresses invasion of Fusobacterium nucleatum into gingival epithelial cells. | Jung YJ, Jun HK, Choi BK. | J Oral Microbiol | 10.1080/20002297.2017.1320193 | 2017 | | |
| Pathogenicity | Tea polyphenols inhibit the growth and virulence properties of Fusobacterium nucleatum. | Ben Lagha A, Haas B, Grenier D. | Sci Rep | 10.1038/srep44815 | 2017 | |
| Malva sylvestris Inhibits Inflammatory Response in Oral Human Cells. An In Vitro Infection Model. | Benso B, Rosalen PL, Alencar SM, Murata RM. | PLoS One | 10.1371/journal.pone.0140331 | 2015 | | |
| Enzymology | Purification, crystallization and preliminary X-ray analysis of two hydrogen sulfide-producing enzymes from Fusobacterium nucleatum. | Kezuka Y, Abe N, Yoshida Y, Nonaka T. | Acta Crystallogr Sect F Struct Biol Cryst Commun | 10.1107/s1744309112042546 | 2012 | |
| Improving the Hydrophobicity of Plasticized Polyvinyl Chloride for Use in an Endotracheal Tube | Marcut L, Mohan A, Corneschi I, Grosu E, Paltanea G, Avram I, Badaluta A, Vasilievici G, Nicolae C, Ditu L. | Materials (Basel) | 2023 | | ||
| Antibacterial activity and cytocompatibility of an implant coating consisting of TiO2 nanotubes combined with a GL13K antimicrobial peptide. | Li T, Wang N, Chen S, Lu R, Li H, Zhang Z. | Int J Nanomedicine | 10.2147/ijn.s128775 | 2017 | | |
| Enzymology | 2-oxoglutarate:acceptor oxidoreductase-catalyzed redox cycling effectively targets coccoid forms of Helicobacter pylori. | Hang X, Lan W, Yanqiang H, Huang H, Zhang M, Zeng L, Shi T, Bai Y, Yang Z, Hu S, Wang J, Dong L, Tong Q, Jia J, Bi S, Xia Q, Gao Y, Bi H. | Nat Commun | 10.1038/s41467-025-62477-4 | 2025 | |
| Anti-Infection of Oral Microorganisms from Herbal Medicine of Piper crocatum Ruiz & Pav. | Kurnia D, Lestari S, Mayanti T, Gartika M, Nurdin D. | Drug Des Devel Ther | 10.2147/dddt.s453375 | 2024 | | |
| Fusobacterium nucleatum-Induced Impairment of Autophagic Flux Enhances the Expression of Proinflammatory Cytokines via ROS in Caco-2 Cells. | Tang B, Wang K, Jia YP, Zhu P, Fang Y, Zhang ZJ, Mao XH, Li Q, Zeng DZ. | PLoS One | 10.1371/journal.pone.0165701 | 2016 | | |
| Adjusting the Dose of Ag-Ion Implantation on TiN-Ag-Modified SLA-Ti Creates Different Micronanostructures: Implications on Bacteriostasis, Biocompatibility, and Osteogenesis in Dental Implants. | Ma M, Zhao M, Ji R, Guo Y, Li D, Zeng S. | ACS Omega | 10.1021/acsomega.3c04769 | 2023 | | |
| Antibiotic Susceptibility and Resistance Genes in Oral Clinical Isolates of Prevotella intermedia, Prevotella nigrescens, and Prevotella melaninogenica. | Castillo Y, Delgadillo NA, Neuta Y, Hernandez A, Acevedo T, Cardenas E, Montano A, Lafaurie GI, Castillo DM. | Antibiotics (Basel) | 10.3390/antibiotics11070888 | 2022 | | |
| Pathogenicity | Influence of the long-term use of oral hygiene products containing stannous ions on the salivary microbiome - a randomized controlled trial. | Anderson AC, Al-Ahmad A, Schlueter N, Frese C, Hellwig E, Binder N. | Sci Rep | 10.1038/s41598-020-66412-z | 2020 | |
| Disruption of Cross-Feeding Inhibits Pathogen Growth in the Sputa of Patients with Cystic Fibrosis. | Flynn JM, Cameron LC, Wiggen TD, Dunitz JM, Harcombe WR, Hunter RC. | mSphere | 10.1128/msphere.00343-20 | 2020 | | |
| Accuracy of commercial kits and published primer pairs for the detection of periodontopathogens. | Santigli E, Leitner E, Wimmer G, Kessler HH, Feierl G, Grube M, Eberhard K, Klug B. | Clin Oral Investig | 10.1007/s00784-016-1748-9 | 2016 | | |
| Biofilms in Diabetic Foot Ulcers: Significance and Clinical Relevance. | Pouget C, Dunyach-Remy C, Pantel A, Schuldiner S, Sotto A, Lavigne JP. | Microorganisms | 10.3390/microorganisms8101580 | 2020 | | |
| Enzymology | High occurrence of Fusobacterium nucleatum and Clostridium difficile in the intestinal microbiota of colorectal carcinoma patients. | Fukugaiti MH, Ignacio A, Fernandes MR, Ribeiro Junior U, Nakano V, Avila-Campos MJ. | Braz J Microbiol | 10.1590/s1517-838246420140665 | 2015 | |
| Evaluation of holy basil mouthwash as an adjunctive plaque control agent in a four day plaque regrowth model. | Hosamane M, Acharya AB, Vij C, Trivedi D, Setty SB, Thakur SL. | J Clin Exp Dent | 10.4317/jced.51479 | 2014 | | |
| Genetics | Target identification in Fusobacterium nucleatum by subtractive genomics approach and enrichment analysis of host-pathogen protein-protein interactions. | Kumar A, Thotakura PL, Tiwary BK, Krishna R. | BMC Microbiol | 10.1186/s12866-016-0700-0 | 2016 | |
| Enzymology | High frequency of enterotoxigenic Bacteroides fragilis and Enterococcus faecalis in the paraffin-embedded tissues of Iranian colorectal cancer patients. | Khodaverdi N, Zeighami H, Jalilvand A, Haghi F, Hesami N. | BMC Cancer | 10.1186/s12885-021-09110-x | 2021 | |
| Periapical bacterial disinfection is critical for dental pulp regenerative cell therapy in apical periodontitis in dogs. | Iohara K, Tominaga M, Watanabe H, Nakashima M. | Stem Cell Res Ther | 10.1186/s13287-023-03628-6 | 2024 | | |
| A Simple Fecal Bacterial Marker Panel for the Diagnosis of Crohn's Disease. | Guo S, Lu Y, Xu B, Wang W, Xu J, Zhang G. | Front Microbiol | 10.3389/fmicb.2019.01306 | 2019 | | |
| Pathogenicity | Antimicrobial and Attractant Roles for Chemerin in the Oral Cavity during Inflammatory Gum Disease. | Godlewska U, Brzoza P, Sroka A, Majewski P, Jentsch H, Eckert M, Eick S, Potempa J, Zabel BA, Cichy J. | Front Immunol | 10.3389/fimmu.2017.00353 | 2017 | |
| The Pharmaceutical Ability of Pistacia lentiscus L. Leaves Essential Oil Against Periodontal Bacteria and Candida sp. and Its Anti-Inflammatory Potential. | Milia E, Usai M, Szotakova B, Elstnerova M, Kralova V, D'hallewin G, Spissu Y, Barberis A, Marchetti M, Bortone A, Campanella V, Mastandrea G, Langhansova L, Eick S. | Antibiotics (Basel) | 10.3390/antibiotics9060281 | 2020 | | |
| Pathogenicity | Anti-Biofilm Property of Bioactive Upconversion Nanocomposites Containing Chlorin e6 against Periodontal Pathogens. | Zhang T, Ying D, Qi M, Li X, Fu L, Sun X, Wang L, Zhou Y. | Molecules | 10.3390/molecules24152692 | 2019 | |
| Human Tumor-Infiltrating MAIT Cells Display Hallmarks of Bacterial Antigen Recognition in Colorectal Cancer. | Li S, Simoni Y, Becht E, Loh CY, Li N, Lachance D, Koo SL, Lim TP, Tan EKW, Mathew R, Nguyen A, Golovato J, Berkson JD, Prlic M, Lee B, Minot SS, Nagarajan N, Dey N, Tan DSW, Tan IB, Newell EW. | Cell Rep Med | 10.1016/j.xcrm.2020.100039 | 2020 | | |
| Enzymology | Cancer-associated fecal microbial markers in colorectal cancer detection. | Eklof V, Lofgren-Burstrom A, Zingmark C, Edin S, Larsson P, Karling P, Alexeyev O, Rutegard J, Wikberg ML, Palmqvist R. | Int J Cancer | 10.1002/ijc.31011 | 2017 | |
| Modulation of Neutrophil Extracellular Trap and Reactive Oxygen Species Release by Periodontal Bacteria. | Hirschfeld J, White PC, Milward MR, Cooper PR, Chapple ILC. | Infect Immun | 10.1128/iai.00297-17 | 2017 | | |
| Comparative evaluation of the efficacy of a herbal mouthwash and chlorhexidine mouthwash on select periodontal pathogens: An in vitro and ex vivo study. | Pathan MM, Bhat KG, Joshi VM. | J Indian Soc Periodontol | 10.4103/jisp.jisp_382_16 | 2017 | | |
| Engineering of Injectable Antibiotic-laden Fibrous Microparticles Gelatin Methacryloyl Hydrogel for Endodontic Infection Ablation. | Ribeiro JS, Munchow EA, Bordini EAF, Rodrigues NS, Dubey N, Sasaki H, Fenno JC, Schwendeman S, Bottino MC. | Int J Mol Sci | 10.3390/ijms23020971 | 2022 | | |
| Enzymology | Fusobacterium nucleatum infection is prevalent in human colorectal carcinoma. | Castellarin M, Warren RL, Freeman JD, Dreolini L, Krzywinski M, Strauss J, Barnes R, Watson P, Allen-Vercoe E, Moore RA, Holt RA. | Genome Res | 10.1101/gr.126516.111 | 2012 | |
| Evaluation of biofilm colonization on multi-part dental implants in a rat model. | Blank E, Grischke J, Winkel A, Eberhard J, Kommerein N, Doll K, Yang I, Stiesch M. | BMC Oral Health | 10.1186/s12903-021-01665-2 | 2021 | | |
| In vitro culture of previously uncultured oral bacterial phylotypes. | Thompson H, Rybalka A, Moazzez R, Dewhirst FE, Wade WG. | Appl Environ Microbiol | 10.1128/aem.02156-15 | 2015 | | |
| Pathogenicity | Regulation of somatostatin receptor 2 by proinflammatory, microbial and obesity-related signals in periodontal cells and tissues. | Memmert S, Damanaki A, Nokhbehsaim M, Nogueira AVB, Eick S, Cirelli JA, Jager A, Deschner J. | Head Face Med | 10.1186/s13005-018-0185-1 | 2019 | |
| Neutrophil elastase aggravates periodontitis by disrupting gingival epithelial barrier via cleaving cell adhesion molecules. | Hiyoshi T, Domon H, Maekawa T, Tamura H, Isono T, Hirayama S, Sasagawa K, Takizawa F, Tabeta K, Terao Y. | Sci Rep | 10.1038/s41598-022-12358-3 | 2022 | | |
| Biological Properties of Aloysia gratissima (Gillies & Hook.) Tronc. (Verbenaceae). | Alijar Souza M, Petry F, Vidor Morgan L, Dal Magro J, Muller LG. | Evid Based Complement Alternat Med | 10.1155/2022/1119435 | 2022 | | |
| Bifidobacterium animalis subsp lactis HN019 presents antimicrobial potential against periodontopathogens and modulates the immunological response of oral mucosa in periodontitis patients. | Invernici MM, Furlaneto FAC, Salvador SL, Ouwehand AC, Salminen S, Mantziari A, Vinderola G, Ervolino E, Santana SI, Silva PHF, Messora MR. | PLoS One | 10.1371/journal.pone.0238425 | 2020 | | |
| Activation and Biological Properties of Human beta Defensin 4 in Stem Cells Derived From Human Exfoliated Deciduous Teeth. | Zhai Y, Wang Y, Rao N, Li J, Li X, Fang T, Zhao Y, Ge L. | Front Physiol | 10.3389/fphys.2019.01304 | 2019 | | |
| Mammalian cell response and bacterial adhesion on titanium healing abutments: effect of multiple implantation and sterilization cycles. | Jain SS, Siddiqui DA, Wheelis SE, Palmer KL, Wilson TG, Rodrigues DC. | Clin Oral Investig | 10.1007/s00784-020-03574-0 | 2021 | | |
| Pathogenicity | Berberine may rescue Fusobacterium nucleatum-induced colorectal tumorigenesis by modulating the tumor microenvironment. | Yu YN, Yu TC, Zhao HJ, Sun TT, Chen HM, Chen HY, An HF, Weng YR, Yu J, Li M, Qin WX, Ma X, Shen N, Hong J, Fang JY. | Oncotarget | 10.18632/oncotarget.5166 | 2015 | |
| Enzymology | Indoleamine 2,3-dioxygenase expression regulates the survival and proliferation of Fusobacterium nucleatum in THP-1-derived macrophages. | Xue Y, Xiao H, Guo S, Xu B, Liao Y, Wu Y, Zhang G. | Cell Death Dis | 10.1038/s41419-018-0389-0 | 2018 | |
| Transcriptome | Worlds Apart - Transcriptome Profiles of Key Oral Microbes in the Periodontal Pocket Compared to Single Laboratory Culture Reflect Synergistic Interactions. | Deng ZL, Sztajer H, Jarek M, Bhuju S, Wagner-Dobler I. | Front Microbiol | 10.3389/fmicb.2018.00124 | 2018 | |
| Immunization with alkyl hydroperoxide reductase subunit C reduces Fusobacterium nucleatum load in the intestinal tract. | Guo SH, Wang HF, Nian ZG, Wang YD, Zeng QY, Zhang G. | Sci Rep | 10.1038/s41598-017-11127-x | 2017 | | |
| The oral microbiota is a reservoir for antimicrobial resistance: resistome and phenotypic resistance characteristics of oral biofilm in health, caries, and periodontitis. | Anderson AC, von Ohle C, Frese C, Boutin S, Bridson C, Schoilew K, Peikert SA, Hellwig E, Pelz K, Wittmer A, Wolff D, Al-Ahmad A. | Ann Clin Microbiol Antimicrob | 10.1186/s12941-023-00585-z | 2023 | | |
| Selective Inhibition of the Periodontal Pathogen Porphyromonas gingivalis by Third-Generation Zafirlukast Derivatives. | Howard KC, Garneau-Tsodikova S. | J Med Chem | 10.1021/acs.jmedchem.2c01471 | 2022 | | |
| Phylogeny | Age and sex-related variations in murine laryngeal microbiota. | An R, Venkatraman A, Binns J, Saric C, Rey FE, Thibeault SL. | PLoS One | 10.1371/journal.pone.0300672 | 2024 | |
| Antimycobacterial and PknB Inhibitory Activities of Venezuelan Medicinal Plants. | Aranaga CA, Fraile S, Torres A, Falco A, Michelangeli F, Takiff H. | Int J Microbiol | 10.1155/2020/8823764 | 2020 | | |
| Pathogenicity | Cytotoxicity and Antimicrobial Activity of Oral Rinses In Vitro. | Muller HD, Eick S, Moritz A, Lussi A, Gruber R. | Biomed Res Int | 10.1155/2017/4019723 | 2017 | |
| Interplay between P. gingivalis, F. nucleatum and A. actinomycetemcomitans in murine alveolar bone loss, arthritis onset and progression. | Ebbers M, Lubcke PM, Volzke J, Kriebel K, Hieke C, Engelmann R, Lang H, Kreikemeyer B, Muller-Hilke B. | Sci Rep | 10.1038/s41598-018-33129-z | 2018 | | |
| Scaling and root planning, and locally delivered minocycline reduces the load of Prevotella intermedia in an interdependent pattern, correlating with symptomatic improvements of chronic periodontitis: a short-term randomized clinical trial. | Deng S, Wang Y, Sun W, Chen H, Wu G. | Ther Clin Risk Manag | 10.2147/tcrm.s93982 | 2015 | | |
| Transcriptome | Relationship between oral anaerobic bacteria and otitis media with effusion. | Topcuoglu N, Keskin F, Ciftci S, Paltura C, Kulekci M, Ustek D, Kulekci G. | Int J Med Sci | 10.7150/ijms.4382 | 2012 | |
| Evaluation of antibody level against Fusobacterium nucleatum in the serological diagnosis of colorectal cancer. | Wang HF, Li LF, Guo SH, Zeng QY, Ning F, Liu WL, Zhang G. | Sci Rep | 10.1038/srep33440 | 2016 | | |
| Interactions between Lactobacillus rhamnosus GG and oral micro-organisms in an in vitro biofilm model. | Jiang Q, Stamatova I, Kainulainen V, Korpela R, Meurman JH. | BMC Microbiol | 10.1186/s12866-016-0759-7 | 2016 | | |
| Metabolism | Regulation of Ghrelin Receptor by Periodontal Bacteria In Vitro and In Vivo. | Nokhbehsaim M, Damanaki A, Nogueira AVB, Eick S, Memmert S, Zhou X, Nanayakkara S, Gotz W, Cirelli JA, Jager A, Deschner J. | Mediators Inflamm | 10.1155/2017/4916971 | 2017 | |
| Detection of hydrogen cyanide from oral anaerobes by cavity ring down spectroscopy. | Chen W, Roslund K, Fogarty CL, Pussinen PJ, Halonen L, Groop PH, Metsala M, Lehto M. | Sci Rep | 10.1038/srep22577 | 2016 | | |
| Pathogenicity | Biofilm-induced profiles of immune response gene expression by oral epithelial cells. | Ebersole JL, Peyyala R, Gonzalez OA. | Mol Oral Microbiol | 10.1111/omi.12251 | 2019 | |
| Metabolism | Forward Genetic Dissection of Biofilm Development by Fusobacterium nucleatum: Novel Functions of Cell Division Proteins FtsX and EnvC. | Wu C, Al Mamun AAM, Luong TT, Hu B, Gu J, Lee JH, D'Amore M, Das A, Ton-That H. | mBio | 10.1128/mbio.00360-18 | 2018 | |
| Artificial Intelligence Applied to Improve Scientific Reviews: The Antibacterial Activity of Cistus Plants as Proof of Concept. | Alvarez-Martinez FJ, Borras-Rocher F, Micol V, Barrajon-Catalan E. | Antibiotics (Basel) | 10.3390/antibiotics12020327 | 2023 | | |
| Coaggregation and biofilm growth of Granulicatella spp. with Fusobacterium nucleatum and Aggregatibacter actinomycetemcomitans. | Karched M, Bhardwaj RG, Asikainen SE. | BMC Microbiol | 10.1186/s12866-015-0439-z | 2015 | | |
| Oral community interactions of Filifactor alocis in vitro. | Wang Q, Wright CJ, Dingming H, Uriarte SM, Lamont RJ. | PLoS One | 10.1371/journal.pone.0076271 | 2013 | | |
| Enzymology | Association between periodontal condition and subgingival microbiota in women during pregnancy: a longitudinal study. | Borgo PV, Rodrigues VA, Feitosa AC, Xavier KC, Avila-Campos MJ. | J Appl Oral Sci | 10.1590/1678-775720140164 | 2014 | |
| Periodontal Application of Manuka Honey: Antimicrobial and Demineralising Effects In Vitro. | Safii SH, Tompkins GR, Duncan WJ. | Int J Dent | 10.1155/2017/9874535 | 2017 | | |
| Enzymology | beta-Glucanase Activity of the Oral Bacterium Tannerella forsythia Contributes to the Growth of a Partner Species, Fusobacterium nucleatum, in Cobiofilms. | Honma K, Ruscitto A, Sharma A. | Appl Environ Microbiol | 10.1128/aem.01759-17 | 2018 | |
| Multifunctional Silver(I) Complexes with Metronidazole Drug Reveal Antimicrobial Properties and Antitumor Activity against Human Hepatoma and Colorectal Adenocarcinoma Cells. | Zyro D, Radko L, Sliwinska A, Checinska L, Kusz J, Korona-Glowniak I, Przekora A, Wojcik M, Posyniak A, Ochocki J. | Cancers (Basel) | 10.3390/cancers14040900 | 2022 | | |
| Pathogenicity | Non-Invasive Photodynamic Therapy against -Periodontitis-causing Bacteria. | Park D, Choi EJ, Weon KY, Lee W, Lee SH, Choi JS, Park GH, Lee B, Byun MR, Baek K, Choi JW. | Sci Rep | 10.1038/s41598-019-44498-4 | 2019 | |
| Pathogenicity | Standard Sample Storage Conditions Have an Impact on Inferred Microbiome Composition and Antimicrobial Resistance Patterns. | Poulsen CS, Kaas RS, Aarestrup FM, Pamp SJ. | Microbiol Spectr | 10.1128/spectrum.01387-21 | 2021 | |
| Mesoporous Hydroxyapatite/Chitosan Loaded With Recombinant-Human Amelogenin Could Enhance Antibacterial Effect and Promote Periodontal Regeneration. | Liao Y, Li H, Shu R, Chen H, Zhao L, Song Z, Zhou W. | Front Cell Infect Microbiol | 10.3389/fcimb.2020.00180 | 2020 | | |
| Role of FAD-I in Fusobacterial Interspecies Interaction and Biofilm Formation. | Shokeen B, Park J, Duong E, Rambhia S, Paul M, Weinberg A, Shi W, Lux R. | Microorganisms | 10.3390/microorganisms8010070 | 2020 | | |
| Diurnal oscillations in human salivary microRNA and microbial transcription: Implications for human health and disease. | Hicks SD, Khurana N, Williams J, Dowd Greene C, Uhlig R, Middleton FA. | PLoS One | 10.1371/journal.pone.0198288 | 2018 | | |
| Composition and Antibacterial Activity of the Essential Oils of Orthosiphon stamineus Benth and Ficus deltoidea Jack against Pathogenic Oral Bacteria. | Azizan N, Mohd Said S, Zainal Abidin Z, Jantan I. | Molecules | 10.3390/molecules22122135 | 2017 | | |
| Metabolism | Strain-specific colonization patterns and serum modulation of multi-species oral biofilm development. | Biyikoglu B, Ricker A, Diaz PI. | Anaerobe | 10.1016/j.anaerobe.2012.06.003 | 2012 | |
| Metabolism | Fusobacterium nucleatum infection of gingival epithelial cells leads to NLRP3 inflammasome-dependent secretion of IL-1beta and the danger signals ASC and HMGB1. | Bui FQ, Johnson L, Roberts J, Hung SC, Lee J, Atanasova KR, Huang PR, Yilmaz O, Ojcius DM. | Cell Microbiol | 10.1111/cmi.12560 | 2016 | |
| Photoinactivation Using Visible Light Plus Water-Filtered Infrared-A (vis+wIRA) and Chlorine e6 (Ce6) Eradicates Planktonic Periodontal Pathogens and Subgingival Biofilms. | Al-Ahmad A, Walankiewicz A, Hellwig E, Follo M, Tennert C, Wittmer A, Karygianni L. | Front Microbiol | 10.3389/fmicb.2016.01900 | 2016 | | |
| Pathogenicity | Action of essential oils from Brazilian native and exotic medicinal species on oral biofilms. | Bersan SM, Galvao LC, Goes VF, Sartoratto A, Figueira GM, Rehder VL, Alencar SM, Duarte RM, Rosalen PL, Duarte MC. | BMC Complement Altern Med | 10.1186/1472-6882-14-451 | 2014 | |
| An experimental murine model to study periodontitis. | Marchesan J, Girnary MS, Jing L, Miao MZ, Zhang S, Sun L, Morelli T, Schoenfisch MH, Inohara N, Offenbacher S, Jiao Y. | Nat Protoc | 10.1038/s41596-018-0035-4 | 2018 | | |
| Bifidobacterium Strains Present Distinct Effects on the Control of Alveolar Bone Loss in a Periodontitis Experimental Model. | Shimabukuro N, Cataruci ACS, Ishikawa KH, de Oliveira BE, Kawamoto D, Ando-Suguimoto ES, Albuquerque-Souza E, Nicoli JR, Ferreira CM, de Lima J, Bueno MR, da Silva LBR, Silva PHF, Messora MR, Camara NOS, Simionato MRL, Mayer MPA. | Front Pharmacol | 10.3389/fphar.2021.713595 | 2021 | | |
| Metabolism | Arginine-Ornithine Antiporter ArcD Controls Arginine Metabolism and Interspecies Biofilm Development of Streptococcus gordonii. | Sakanaka A, Kuboniwa M, Takeuchi H, Hashino E, Amano A. | J Biol Chem | 10.1074/jbc.m115.644401 | 2015 | |
| Arthritic role of Porphyromonas gingivalis in collagen-induced arthritis mice. | Jung H, Jung SM, Rim YA, Park N, Nam Y, Lee J, Park SH, Ju JH. | PLoS One | 10.1371/journal.pone.0188698 | 2017 | | |
| Prevalence of target anaerobes associated with chronic periodontitis. | Alazemi AM, Jamal W, Al Khabbaz A, Rotimi VO. | Access Microbiol | 10.1099/acmi.0.000177 | 2020 | | |
| Berberine-Functionalized Bismuth-Doped Carbon Dots in a Pathogen-Responsive Hydrogel System: A Multifaceted Approach to Combating Periodontal Diseases. | Li X, Huang R, Li P, Tang FK, He J, Sun H, Wang X, Wang M, Lan X, Wang X, Wong SSW, Jin L, Leung KC, Wong HM, Wang S, Guo L, Ding PH, Yu X. | ACS Nano | 10.1021/acsnano.5c00561 | 2025 | | |
| Enzymology | Bacteriological analysis of necrotic pulp and fistulae in primary teeth. | Fabris AS, Nakano V, Avila-Campos MJ. | J Appl Oral Sci | 10.1590/1678-775720130358 | 2014 | |
| Fusobacterium nucleatum apoptosis-inducing outer membrane protein. | Kaplan CW, Lux R, Huynh T, Jewett A, Shi W, Haake SK. | J Dent Res | 10.1177/154405910508400803 | 2005 | | |
| Locoregional Effects of Microbiota in a Preclinical Model of Colon Carcinogenesis. | Tomkovich S, Yang Y, Winglee K, Gauthier J, Muhlbauer M, Sun X, Mohamadzadeh M, Liu X, Martin P, Wang GP, Oswald E, Fodor AA, Jobin C. | Cancer Res | 10.1158/0008-5472.can-16-3472 | 2017 | | |
| Antimicrobial Activity and Chemical Composition of Essential Oils from Verbenaceae Species Growing in South America. | Perez Zamora CM, Torres CA, Nunez MB. | Molecules | 10.3390/molecules23030544 | 2018 | | |
| Identification of Substances Produced by Cercospora brachiata in Absence of Light and Evaluation of Antibacterial Activity. | Felisbino JKRP, Vieira BS, de Oliveira A, da Silva NA, Martins CHG, Santiago MB, Munoz RAA, Cunha LCS, Sousa RMF. | J Fungi (Basel) | 10.3390/jof7090680 | 2021 | | |
| Metabolism | Bioorthogonal non-canonical amino acid tagging reveals translationally active subpopulations of the cystic fibrosis lung microbiota. | Valentini TD, Lucas SK, Binder KA, Cameron LC, Motl JA, Dunitz JM, Hunter RC. | Nat Commun | 10.1038/s41467-020-16163-2 | 2020 | |
| Metabolism | The Fusobacterium nucleatum outer membrane protein RadD is an arginine-inhibitable adhesin required for inter-species adherence and the structured architecture of multispecies biofilm. | Kaplan CW, Lux R, Haake SK, Shi W. | Mol Microbiol | 10.1111/j.1365-2958.2008.06503.x | 2009 | |
| Kampo Therapies and the Use of Herbal Medicines in the Dentistry in Japan. | Watanabe S, Toyama T, Sato T, Suzuki M, Morozumi A, Sakagami H, Hamada N. | Medicines (Basel) | 10.3390/medicines6010034 | 2019 | | |
| Copper-containing nanoparticles: Mechanism of antimicrobial effect and application in dentistry-a narrative review. | Ma X, Zhou S, Xu X, Du Q. | Front Surg | 10.3389/fsurg.2022.905892 | 2022 | | |
| Modulation of pathogenic oral biofilms towards health with nisin probiotic. | Radaic A, Ye C, Parks B, Gao L, Kuraji R, Malone E, Kamarajan P, Zhan L, Kapila YL. | J Oral Microbiol | 10.1080/20002297.2020.1809302 | 2020 | | |
| Toxicological Effects of Copaiba Oil (Copaifera spp.) and Its Active Components. | Cardinelli CC, Silva JEAE, Ribeiro R, Veiga-Junior VF, Santos EPD, de Freitas ZMF. | Plants (Basel) | 10.3390/plants12051054 | 2023 | | |
| Enzymology | Isolation of a novel bacteriophage specific for the periodontal pathogen Fusobacterium nucleatum. | Machuca P, Daille L, Vines E, Berrocal L, Bittner M. | Appl Environ Microbiol | 10.1128/aem.01135-10 | 2010 | |
| Metabolism | Fusobacterium nucleatum envelope protein FomA is immunogenic and binds to the salivary statherin-derived peptide. | Nakagaki H, Sekine S, Terao Y, Toe M, Tanaka M, Ito HO, Kawabata S, Shizukuishi S, Fujihashi K, Kataoka K. | Infect Immun | 10.1128/iai.01224-09 | 2010 | |
| Antibacterial Effect of Copaifera duckei Dwyer Oleoresin and Its Main Diterpenes against Oral Pathogens and Their Cytotoxic Effect. | Abrao F, Alves JA, Andrade G, de Oliveira PF, Ambrosio SR, Veneziani RCS, Tavares DC, Bastos JK, Martins CHG. | Front Microbiol | 10.3389/fmicb.2018.00201 | 2018 | | |
| Pathogenicity | The Kampo medicine Rokumigan possesses antibiofilm, anti-inflammatory, and wound healing properties. | Liao J, Azelmat J, Zhao L, Yoshioka M, Hinode D, Grenier D. | Biomed Res Int | 10.1155/2014/436206 | 2014 | |
| Combined Release of Antiseptic and Antibiotic Drugs from Visible Light Polymerized Biodegradable Nanocomposite Hydrogels for Periodontitis Treatment. | Bako J, Toth F, Gall J, Kovacs R, Csik A, Varga I, Sculean A, Zelko R, Hegedus C. | Pharmaceutics | 10.3390/pharmaceutics14050957 | 2022 | | |
| Chemical Constituents and Antileishmanial and Antibacterial Activities of Essential Oils from Scheelea phalerata. | Oliveira DM, Furtado FB, Gomes AAS, Belut BR, Nascimento EA, Morais SAL, Martins CHG, Santos VCO, da Silva CV, Teixeira TL, Cunha LCS, Oliveira A, de Aquino FJT. | ACS Omega | 10.1021/acsomega.9b01962 | 2020 | | |
| Abnormal pregnancy outcomes in mice using an induced periodontitis model and the haematogenous migration of Fusobacterium nucleatum sub-species to the murine placenta. | Stockham S, Stamford JE, Roberts CT, Fitzsimmons TR, Marchant C, Bartold PM, Zilm PS. | PLoS One | 10.1371/journal.pone.0120050 | 2015 | | |
| Metabolism | Signal peptide of FadA adhesin from Fusobacterium nucleatum plays a novel structural role by modulating the filament's length and width. | Temoin S, Wu KL, Wu V, Shoham M, Han YW. | FEBS Lett | 10.1016/j.febslet.2011.10.047 | 2012 | |
| Beneficial Role of Antioxidant Secondary Metabolites from Medicinal Plants in Maintaining Oral Health. | Kumar M, Prakash S, Radha, Kumari N, Pundir A, Punia S, Saurabh V, Choudhary P, Changan S, Dhumal S, Pradhan PC, Alajil O, Singh S, Sharma N, Ilakiya T, Singh S, Mekhemar M. | Antioxidants (Basel) | 10.3390/antiox10071061 | 2021 | | |
| Medicinal Uses, Phytochemistry, and Pharmacological Activities of Quercus Species. | Taib M, Rezzak Y, Bouyazza L, Lyoussi B. | Evid Based Complement Alternat Med | 10.1155/2020/1920683 | 2020 | | |
| Phylogeny | Comparison of oral microbiota in tumor and non-tumor tissues of patients with oral squamous cell carcinoma. | Pushalkar S, Ji X, Li Y, Estilo C, Yegnanarayana R, Singh B, Li X, Saxena D. | BMC Microbiol | 10.1186/1471-2180-12-144 | 2012 | |
| Antimicrobial Photodynamic Therapy to Control Clinically Relevant Biofilm Infections. | Hu X, Huang YY, Wang Y, Wang X, Hamblin MR. | Front Microbiol | 10.3389/fmicb.2018.01299 | 2018 | | |
| Metabolism | Subgingival Plaque in Periodontal Health Antagonizes at Toll-Like Receptor 4 and Inhibits E-Selectin Expression on Endothelial Cells. | To TT, Gumus P, Nizam N, Buduneli N, Darveau RP. | Infect Immun | 10.1128/iai.00693-15 | 2016 | |
| The effect of supragingival glycine air polishing on periodontitis during maintenance therapy: a randomized controlled trial. | Lu H, Lu H, He L, Zhao Y, Meng H. | PeerJ | 10.7717/peerj.4371 | 2018 | | |
| Bactericidal effects of 310 nm ultraviolet light-emitting diode irradiation on oral bacteria. | Takada A, Matsushita K, Horioka S, Furuichi Y, Sumi Y. | BMC Oral Health | 10.1186/s12903-017-0382-5 | 2017 | | |
| Phenotype | Human Primary Epithelial Cells Acquire an Epithelial-Mesenchymal-Transition Phenotype during Long-Term Infection by the Oral Opportunistic Pathogen, Porphyromonas gingivalis. | Lee J, Roberts JS, Atanasova KR, Chowdhury N, Han K, Yilmaz O. | Front Cell Infect Microbiol | 10.3389/fcimb.2017.00493 | 2017 | |
| Enzymology | Genetic and biochemical characterization of FUS-1 (OXA-85), a narrow-spectrum class D beta-lactamase from Fusobacterium nucleatum subsp. polymorphum. | Voha C, Docquier JD, Rossolini GM, Fosse T. | Antimicrob Agents Chemother | 10.1128/aac.00058-06 | 2006 | |
| In Vitro and In Vivo Properties of CUO246, a Novel Bacterial DNA Gyrase/Topoisomerase IV Inhibitor. | Blais J, Dean CR, Lapointe G, Leeds JA, Ma S, Morris L, Moser HE, Osborne CS, Prosen KR, Richie D, Skepper C, Thompson K, Vo J, Yue Q, Rivkin A. | Antimicrob Agents Chemother | 10.1128/aac.00921-22 | 2022 | | |
| Metabolism | Diverse Toll-like receptors mediate cytokine production by Fusobacterium nucleatum and Aggregatibacter actinomycetemcomitans in macrophages. | Park SR, Kim DJ, Han SH, Kang MJ, Lee JY, Jeong YJ, Lee SJ, Kim TH, Ahn SG, Yoon JH, Park JH. | Infect Immun | 10.1128/iai.01226-13 | 2014 | |
| Pathogenicity | A Rapid and Quantitative Flow Cytometry Method for the Analysis of Membrane Disruptive Antimicrobial Activity. | O'Brien-Simpson NM, Pantarat N, Attard TJ, Walsh KA, Reynolds EC. | PLoS One | 10.1371/journal.pone.0151694 | 2016 | |
| Role of Cathepsin S in Periodontal Inflammation and Infection. | Memmert S, Damanaki A, Nogueira AVB, Eick S, Nokhbehsaim M, Papadopoulou AK, Till A, Rath B, Jepsen S, Gotz W, Piperi C, Basdra EK, Cirelli JA, Jager A, Deschner J. | Mediators Inflamm | 10.1155/2017/4786170 | 2017 | | |
| Pathogenicity | Resolving the Contradictory Functions of Lysine Decarboxylase and Butyrate in Periodontal and Intestinal Diseases. | Levine M, Lohinai ZM. | J Clin Med | 10.3390/jcm10112360 | 2021 | |
| Triterpenoid Saponins from Washnut (Sapindus mukorossi Gaertn.)-A Source of Natural Surfactants and Other Active Components. | Sochacki M, Vogt O. | Plants (Basel) | 10.3390/plants11182355 | 2022 | | |
| Screening for antibacterial and antibiofilm activity in Thai medicinal plant extracts against oral microorganisms. | Teanpaisan R, Kawsud P, Pahumunto N, Puripattanavong J. | J Tradit Complement Med | 10.1016/j.jtcme.2016.06.007 | 2017 | | |
| Pathogenicity | Nanoparticle-encapsulated chlorhexidine against oral bacterial biofilms. | Seneviratne CJ, Leung KC, Wong CH, Lee SF, Li X, Leung PC, Lau CB, Wat E, Jin L. | PLoS One | 10.1371/journal.pone.0103234 | 2014 | |
| Axenic culture of a candidate division TM7 bacterium from the human oral cavity and biofilm interactions with other oral bacteria. | Soro V, Dutton LC, Sprague SV, Nobbs AH, Ireland AJ, Sandy JR, Jepson MA, Micaroni M, Splatt PR, Dymock D, Jenkinson HF. | Appl Environ Microbiol | 10.1128/aem.01827-14 | 2014 | | |
| Interleukin-1 and estrogen protect against disseminating dentoalveolar infections. | Youssef H, Stashenko P. | Int J Oral Sci | 10.1038/ijos.2016.61 | 2017 | | |
| Pathogenicity | Fusobacterium nucleatum Promotes Chemoresistance to Colorectal Cancer by Modulating Autophagy. | Yu T, Guo F, Yu Y, Sun T, Ma D, Han J, Qian Y, Kryczek I, Sun D, Nagarsheth N, Chen Y, Chen H, Hong J, Zou W, Fang JY. | Cell | 10.1016/j.cell.2017.07.008 | 2017 | |
| Pathogenicity | Quercetin Preserves Oral Cavity Health by Mitigating Inflammation and Microbial Dysbiosis. | Mooney EC, Holden SE, Xia XJ, Li Y, Jiang M, Banson CN, Zhu B, Sahingur SE. | Front Immunol | 10.3389/fimmu.2021.774273 | 2021 | |
| Bimix antimicrobial scaffolds for regenerative endodontics. | Palasuk J, Kamocki K, Hippenmeyer L, Platt JA, Spolnik KJ, Gregory RL, Bottino MC. | J Endod | 10.1016/j.joen.2014.07.017 | 2014 | | |
| Associations of streptococci and fungi amounts in the oral cavity with nutritional and oral health status in institutionalized elders: a cross sectional study. | Sato H, Yano A, Shimoyama Y, Sato T, Sugiyama Y, Kishi M. | BMC Oral Health | 10.1186/s12903-021-01926-0 | 2021 | | |
| Leaves and Fruits Preparations of Pistacia lentiscus L.: A Review on the Ethnopharmacological Uses and Implications in Inflammation and Infection. | Milia E, Bullitta SM, Mastandrea G, Szotakova B, Schoubben A, Langhansova L, Quartu M, Bortone A, Eick S. | Antibiotics (Basel) | 10.3390/antibiotics10040425 | 2021 | | |
| Short-term microbiological effects of scaling and root planing and essential-oils mouthwash in Chinese adults. | He JY, Qi GG, Huang WJ, Sun XD, Tong Y, Peng CM, Zhou XP, Chen H. | J Zhejiang Univ Sci B | 10.1631/jzus.b1200350 | 2013 | | |
| Pathogenicity | Oral epithelial cell responses to multispecies microbial biofilms. | Peyyala R, Kirakodu SS, Novak KF, Ebersole JL. | J Dent Res | 10.1177/0022034512472508 | 2013 | |
| Metabolism | Nucleases from Prevotella intermedia can degrade neutrophil extracellular traps. | Doke M, Fukamachi H, Morisaki H, Arimoto T, Kataoka H, Kuwata H. | Mol Oral Microbiol | 10.1111/omi.12171 | 2017 | |
| In Vitro Evaluation of Antimicrobial Activity of Minocycline Formulations for Topical Application in Periodontal Therapy. | Schmid JL, Kirchberg M, Sarembe S, Kiesow A, Sculean A, Mader K, Buchholz M, Eick S. | Pharmaceutics | 10.3390/pharmaceutics12040352 | 2020 | | |
| Metabolism | Fusobacterium nucleatum increases collagenase 3 production and migration of epithelial cells. | Uitto VJ, Baillie D, Wu Q, Gendron R, Grenier D, Putnins EE, Kanervo A, Firth JD. | Infect Immun | 10.1128/iai.73.2.1171-1179.2005 | 2005 | |
| Assessing and removing the effect of unwanted technical variations in microbiome data. | Fachrul M, Meric G, Inouye M, Pamp SJ, Salim A. | Sci Rep | 10.1038/s41598-022-26141-x | 2022 | | |
| Genetics | The efficiency of Nextera XT tagmentation depends on G and C bases in the binding motif leading to uneven coverage in bacterial species with low and neutral GC-content. | Segerman B, Astvaldsson A, Mustafa L, Skarin J, Skarin H. | Front Microbiol | 10.3389/fmicb.2022.944770 | 2022 | |
| Metabolism | Methylene Blue-Mediated Photodynamic Therapy Induces Macrophage Apoptosis via ROS and Reduces Bone Resorption in Periodontitis. | Jiang C, Yang W, Wang C, Qin W, Ming J, Zhang M, Qian H, Jiao T. | Oxid Med Cell Longev | 10.1155/2019/1529520 | 2019 | |
| Interactions of anaerobic bacteria with dental stem cells: an in vitro study. | Biedermann A, Kriebel K, Kreikemeyer B, Lang H. | PLoS One | 10.1371/journal.pone.0110616 | 2014 | | |
| Metabolism | DNA methylation differentially regulates cytokine secretion in gingival epithelia in response to bacterial challenges. | Drury JL, Chung WO. | Pathog Dis | 10.1093/femspd/ftu005 | 2015 | |
| Pathogenicity | Antimicrobial activity of diterpenes from Viguiera arenaria against endodontic bacteria. | Carvalho TC, Simao MR, Ambrosio SR, Furtado NA, Veneziani RC, Heleno VC, Da Costa FB, Gomes BP, Souza MG, Borges dos Reis E, Martins CH. | Molecules | 10.3390/molecules160100543 | 2011 | |
| Minigene as a Novel Regulatory Element in Toxin-Antitoxin Systems. | Kedzierska B, Potrykus K. | Int J Mol Sci | 10.3390/ijms222413389 | 2021 | | |
| Metabolism | Binding of pro-matrix metalloproteinase 9 by Fusobacterium nucleatum subsp. nucleatum as a mechanism to promote the invasion of a reconstituted basement membrane. | Gendron R, Plamondon P, Grenier D. | Infect Immun | 10.1128/iai.72.10.6160-6163.2004 | 2004 | |
| Identification of intracellular bacteria from multiple single-cell RNA-seq platforms using CSI-Microbes. | Robinson W, Stone JK, Schischlik F, Gasmi B, Kelly MC, Seibert C, Dadkhah K, Gertz EM, Lee JS, Zhu K, Ma L, Wang XW, Sahinalp SC, Patro R, Leiserson MDM, Harris CC, Schaffer AA, Ruppin E. | Sci Adv | 10.1126/sciadv.adj7402 | 2024 | | |
| Metabolism | The role of acidification in the inhibition of Neisseria gonorrhoeae by vaginal lactobacilli during anaerobic growth. | Graver MA, Wade JJ. | Ann Clin Microbiol Antimicrob | 10.1186/1476-0711-10-8 | 2011 | |
| Pathogenicity | Antibacterial effects of blackberry extract target periodontopathogens. | Gonzalez OA, Escamilla C, Danaher RJ, Dai J, Ebersole JL, Mumper RJ, Miller CS. | J Periodontal Res | 10.1111/j.1600-0765.2012.01506.x | 2013 | |
| Graphene oxide and mineralized collagen-functionalized dental implant abutment with effective soft tissue seal and romotely repeatable photodisinfection. | Gao Y, Kang K, Luo B, Sun X, Lan F, He J, Wu Y. | Regen Biomater | 10.1093/rb/rbac024 | 2022 | | |
| Metabolism | Reactivation of latent HIV-1 by a wide variety of butyric acid-producing bacteria. | Imai K, Yamada K, Tamura M, Ochiai K, Okamoto T. | Cell Mol Life Sci | 10.1007/s00018-012-0936-2 | 2012 | |
| Genetics | Comparative In silico Analysis of Butyrate Production Pathways in Gut Commensals and Pathogens. | Anand S, Kaur H, Mande SS. | Front Microbiol | 10.3389/fmicb.2016.01945 | 2016 | |
| Genetics | Multilaboratory assessment of metagenomic next-generation sequencing for unbiased microbe detection. | Han D, Diao Z, Lai H, Han Y, Xie J, Zhang R, Li J. | J Adv Res | 10.1016/j.jare.2021.09.011 | 2022 | |
| Genetics | Bacterial Protein Interaction Networks: Connectivity is Ruled by Gene Conservation, Essentiality and Function. | Dilucca M, Cimini G, Giansanti A. | Curr Genomics | 10.2174/1389202922666210219110831 | 2021 | |
| Metabolism | Fusobacterium nucleatum outer membrane proteins Fap2 and RadD induce cell death in human lymphocytes. | Kaplan CW, Ma X, Paranjpe A, Jewett A, Lux R, Kinder-Haake S, Shi W. | Infect Immun | 10.1128/iai.00567-10 | 2010 | |
| Pathogenicity | The oralome and its dysbiosis: New insights into oral microbiome-host interactions. | Radaic A, Kapila YL. | Comput Struct Biotechnol J | 10.1016/j.csbj.2021.02.010 | 2021 | |
| Modeling of diffusion transport through oral biofilms with the inverse problem method. | Ma R, Liu J, Jiang YT, Liu Z, Tang ZS, Ye DX, Zeng J, Huang ZW. | Int J Oral Sci | 10.4248/ijos10075 | 2010 | | |
| TIR domain-containing adaptor SARM is a late addition to the ongoing microbe-host dialog. | Zhang Q, Zmasek CM, Cai X, Godzik A. | Dev Comp Immunol | 10.1016/j.dci.2010.11.013 | 2011 | | |
| A variable gene in a conserved region of the Helicobacter pylori genome: isotopic gene replacement or rapid evolution? | Menard A, Danchin A, Dupouy S, Megraud F, Lehours P. | DNA Res | 10.1093/dnares/dsn006 | 2008 | | |
| Selective bacterial degradation of the extracellular matrix attaching the gingiva to the tooth. | Fouillen A, Grenier D, Barbeau J, Baron C, Moffatt P, Nanci A. | Eur J Oral Sci | 10.1111/eos.12623 | 2019 | | |
| Antimicrobial nisin acts against saliva derived multi-species biofilms without cytotoxicity to human oral cells. | Shin JM, Ateia I, Paulus JR, Liu H, Fenno JC, Rickard AH, Kapila YL. | Front Microbiol | 10.3389/fmicb.2015.00617 | 2015 | | |
| Genetics | In Silico Analysis of Putrefaction Pathways in Bacteria and Its Implication in Colorectal Cancer. | Kaur H, Das C, Mande SS. | Front Microbiol | 10.3389/fmicb.2017.02166 | 2017 | |
| Pathogenicity | Endodontic Infection-induced Inflammation Resembling Osteomyelitis of the Jaws in Toll-like Receptor 2/Interleukin 10 Double-knockout Mice. | Sasaki H, Furusho H, Rider DB, Dobeck JM, Kuo WP, Fujimura A, Yoganathan S, Hirai K, Xu S, Sasaki K, Stashenko P. | J Endod | 10.1016/j.joen.2018.10.007 | 2019 | |
| Oral microbiota and host innate immune response in bisphosphonate-related osteonecrosis of the jaw. | Pushalkar S, Li X, Kurago Z, Ramanathapuram LV, Matsumura S, Fleisher KE, Glickman R, Yan W, Li Y, Saxena D. | Int J Oral Sci | 10.1038/ijos.2014.46 | 2014 | | |
| Metabolism | Distribution of glucan-branching enzymes among prokaryotes. | Suzuki E, Suzuki R. | Cell Mol Life Sci | 10.1007/s00018-016-2243-9 | 2016 | |
| Enzymology | Mammalian-like type II glutaminyl cyclases in Porphyromonas gingivalis and other oral pathogenic bacteria as targets for treatment of periodontitis. | Taudte N, Linnert M, Rahfeld JU, Piechotta A, Ramsbeck D, Buchholz M, Kolenko P, Parthier C, Houston JA, Veillard F, Eick S, Potempa J, Schilling S, Demuth HU, Stubbs MT. | J Biol Chem | 10.1016/j.jbc.2021.100263 | 2021 | |
| Phylogeny | Molecular profiling of oral microbiota in jawbone samples of bisphosphonate-related osteonecrosis of the jaw. | Wei X, Pushalkar S, Estilo C, Wong C, Farooki A, Fornier M, Bohle G, Huryn J, Li Y, Doty S, Saxena D. | Oral Dis | 10.1111/j.1601-0825.2012.01916.x | 2012 | |
| Antibody and T cell responses to Fusobacterium nucleatum and Treponema denticola in health and chronic periodontitis. | Shin J, Kho SA, Choi YS, Kim YC, Rhyu IC, Choi Y. | PLoS One | 10.1371/journal.pone.0053703 | 2013 | | |
| Short- and medium-chain fatty acids exhibit antimicrobial activity for oral microorganisms. | Huang CB, Alimova Y, Myers TM, Ebersole JL. | Arch Oral Biol | 10.1016/j.archoralbio.2011.01.011 | 2011 | | |
| Bacterial infection promotes tumorigenesis of colorectal cancer via regulating CDC42 acetylation. | Wang DN, Ni JJ, Li JH, Gao YQ, Ni FJ, Zhang ZZ, Fang JY, Lu J, Yao YF. | PLoS Pathog | 10.1371/journal.ppat.1011189 | 2023 | | |
| Metabolism | Porphyromonas gingivalis induces penetration of lipopolysaccharide and peptidoglycan through the gingival epithelium via degradation of junctional adhesion molecule 1. | Takeuchi H, Sasaki N, Yamaga S, Kuboniwa M, Matsusaki M, Amano A. | PLoS Pathog | 10.1371/journal.ppat.1008124 | 2019 | |
| Large-Scale Molecular Evolutionary Analysis Uncovers a Variety of Polynucleotide Kinase Clp1 Family Proteins in the Three Domains of Life. | Saito M, Sato A, Nagata S, Tamaki S, Tomita M, Suzuki H, Kanai A. | Genome Biol Evol | 10.1093/gbe/evz195 | 2019 | | |
| Metabolism | Epithelial interleukin-8 responses to oral bacterial biofilms. | Peyyala R, Kirakodu S, Novak KF, Ebersole JL. | Clin Vaccine Immunol | 10.1128/cvi.05162-11 | 2011 | |
| Metabolism | Porphyromonas gingivalis initiates a mesenchymal-like transition through ZEB1 in gingival epithelial cells. | Sztukowska MN, Ojo A, Ahmed S, Carenbauer AL, Wang Q, Shumway B, Jenkinson HF, Wang H, Darling DS, Lamont RJ. | Cell Microbiol | 10.1111/cmi.12554 | 2016 | |
| Metabolism | Association of purine asymmetry, strand-biased gene distribution and PolC within Firmicutes and beyond: a new appraisal. | Saha SK, Goswami A, Dutta C. | BMC Genomics | 10.1186/1471-2164-15-430 | 2014 | |
| Metabolism | Epigenetic regulation of human beta-defensin 2 and CC chemokine ligand 20 expression in gingival epithelial cells in response to oral bacteria. | Yin L, Chung WO. | Mucosal Immunol | 10.1038/mi.2010.83 | 2011 | |
| Effects of tongue cleaning on bacterial flora in tongue coating and dental plaque: a crossover study. | Matsui M, Chosa N, Shimoyama Y, Minami K, Kimura S, Kishi M. | BMC Oral Health | 10.1186/1472-6831-14-4 | 2014 | | |
| A five-species transcriptome array for oral mixed-biofilm studies. | Redanz S, Standar K, Podbielski A, Kreikemeyer B. | PLoS One | 10.1371/journal.pone.0027827 | 2011 | | |
| Serum antibodies to periodontal pathogens are a risk factor for Alzheimer's disease. | Sparks Stein P, Steffen MJ, Smith C, Jicha G, Ebersole JL, Abner E, Dawson D. | Alzheimers Dement | 10.1016/j.jalz.2011.04.006 | 2012 | | |
| MicroRNA-138 Inhibits Periodontal Progenitor Differentiation under Inflammatory Conditions. | Zhou X, Luan X, Chen Z, Francis M, Gopinathan G, Li W, Lu X, Li S, Wu C, Diekwisch TG. | J Dent Res | 10.1177/0022034515613043 | 2016 | | |
| Metabolism | Sonoporation is an efficient tool for intracellular fluorescent dextran delivery and one-step double-crossover mutant construction in Fusobacterium nucleatum. | Han YW, Ikegami A, Chung P, Zhang L, Deng CX. | Appl Environ Microbiol | 10.1128/aem.00428-07 | 2007 | |
| Purification and Anti-pathogenic Properties of Immunoglobulin Concentrates from Porcine Blood. | Jung TH, Choi JH, Koh KC, Jeon WM, Han KS. | Korean J Food Sci Anim Resour | 10.5851/kosfa.2017.37.5.743 | 2017 | | |
| Metabolism | Ubiquitous sialometabolism present among oral fusobacteria. | Yoneda S, Loeser B, Feng J, Dmytryk J, Qi F, Merritt J. | PLoS One | 10.1371/journal.pone.0099263 | 2014 | |
| Fusobacterium nucleatum and Tannerella forsythia induce synergistic alveolar bone loss in a mouse periodontitis model. | Settem RP, El-Hassan AT, Honma K, Stafford GP, Sharma A. | Infect Immun | 10.1128/iai.06276-11 | 2012 | | |
| Pathogenicity | In-vitro antibiofilm activity of chlorhexidine digluconate on polylactide-based and collagen-based membranes. | Rudolf JL, Moser C, Sculean A, Eick S. | BMC Oral Health | 10.1186/s12903-019-0979-y | 2019 | |
| Antibiotic effects on bacterial profile in osteonecrosis of the jaw. | Ji X, Pushalkar S, Li Y, Glickman R, Fleisher K, Saxena D. | Oral Dis | 10.1111/j.1601-0825.2011.01848.x | 2012 | | |
| Regulation and Molecular Basis of Environmental Muropeptide Uptake and Utilization in Fastidious Oral Anaerobe Tannerella forsythia. | Ruscitto A, Honma K, Veeramachineni VM, Nishikawa K, Stafford GP, Sharma A. | Front Microbiol | 10.3389/fmicb.2017.00648 | 2017 | | |
| Pathogenicity | Effect of an oxygenating agent on oral bacteria in vitro and on dental plaque composition in healthy young adults. | Fernandez y Mostajo M, van der Reijden WA, Buijs MJ, Beertsen W, Van der Weijden F, Crielaard W, Zaura E. | Front Cell Infect Microbiol | 10.3389/fcimb.2014.00095 | 2014 | |
| Interactions between periodontal bacteria and human oral epithelial cells: Fusobacterium nucleatum adheres to and invades epithelial cells. | Han YW, Shi W, Huang GT, Kinder Haake S, Park NH, Kuramitsu H, Genco RJ. | Infect Immun | 10.1128/iai.68.6.3140-3146.2000 | 2000 | | |
| Antimicrobial Activity of Chemokine CXCL10 for Dermal and Oral Microorganisms. | Holdren GO, Rosenthal DJ, Yang J, Bates AM, Fischer CL, Zhang Y, Brogden NK, Brogden KA. | Antibiotics (Basel) | 10.3390/antibiotics3040527 | 2014 | | |
| Metabolism | Oral microbial biofilm stimulation of epithelial cell responses. | Peyyala R, Kirakodu SS, Novak KF, Ebersole JL. | Cytokine | 10.1016/j.cyto.2011.12.016 | 2012 | |
| Pathogenicity | In vitro-activity of oily calcium hydroxide suspension on microorganisms as well as on human alveolar osteoblasts and periodontal ligament fibroblasts. | Eick S, Strugar T, Miron RJ, Sculean A. | BMC Oral Health | 10.1186/1472-6831-14-9 | 2014 | |
| Metabolism | The surface layer of Tannerella forsythia contributes to serum resistance and oral bacterial coaggregation. | Shimotahira N, Oogai Y, Kawada-Matsuo M, Yamada S, Fukutsuji K, Nagano K, Yoshimura F, Noguchi K, Komatsuzawa H. | Infect Immun | 10.1128/iai.00983-12 | 2013 | |
| Pathogenicity | Chemical composition, cytotoxic and antimicrobial activity of essential oils from Cassia bakeriana Craib. against aerobic and anaerobic oral pathogens. | Cunha LC, de Morais SA, Martins CH, Martins MM, Chang R, de Aquino FJ, de Oliveira A, Moraes Tda S, Machado FC, da Silva CV, do Nascimento EA. | Molecules | 10.3390/molecules18044588 | 2013 | |
| Seasonal variation of the chemical composition and antimicrobial and cytotoxic activities of the essential oils from Inga laurina (Sw.) Willd. | Furtado FB, de Aquino FJ, Nascimento EA, de M Martins C, de Morais SA, Chang R, Cunha LC, Leandro LF, Martins CH, Martins MM, da Silva CV, Machado FC, de Oliveira A. | Molecules | 10.3390/molecules19044560 | 2014 | | |
| Effects of azithromycin, metronidazole, amoxicillin, and metronidazole plus amoxicillin on an in vitro polymicrobial subgingival biofilm model. | Soares GM, Teles F, Starr JR, Feres M, Patel M, Martin L, Teles R. | Antimicrob Agents Chemother | 10.1128/aac.04974-14 | 2015 | | |
| Metabolism | Fusobacterium nucleatum and human beta-defensins modulate the release of antimicrobial chemokine CCL20/macrophage inflammatory protein 3alpha. | Ghosh SK, Gupta S, Jiang B, Weinberg A. | Infect Immun | 10.1128/iai.05586-11 | 2011 | |
| Metabolism | Porphyromonas gingivalis promotes invasion of oral squamous cell carcinoma through induction of proMMP9 and its activation. | Inaba H, Sugita H, Kuboniwa M, Iwai S, Hamada M, Noda T, Morisaki I, Lamont RJ, Amano A. | Cell Microbiol | 10.1111/cmi.12211 | 2014 | |
| F. nucleatum facilitates oral squamous cell carcinoma progression via GLUT1-driven lactate production. | Sun J, Tang Q, Yu S, Xie M, Zheng W, Chen G, Yin Y, Huang X, Wo K, Lei H, Zhang J, Wan Q, Chen L. | EBioMedicine | 10.1016/j.ebiom.2023.104444 | 2023 | | |
| The peptidylarginine deiminase gene is a conserved feature of Porphyromonas gingivalis. | Gabarrini G, de Smit M, Westra J, Brouwer E, Vissink A, Zhou K, Rossen JW, Stobernack T, van Dijl JM, van Winkelhoff AJ. | Sci Rep | 10.1038/srep13936 | 2015 | | |
| Enzymology | pH gradient and distribution of streptococci, lactobacilli, prevotellae, and fusobacteria in carious dentine. | Kianoush N, Nguyen KA, Browne GV, Simonian M, Hunter N. | Clin Oral Investig | 10.1007/s00784-013-1009-0 | 2014 | |
| Metabolism | A novel acyl-CoA beta-transaminase characterized from a metagenome. | Perret A, Lechaplais C, Tricot S, Perchat N, Vergne C, Pelle C, Bastard K, Kreimeyer A, Vallenet D, Zaparucha A, Weissenbach J, Salanoubat M. | PLoS One | 10.1371/journal.pone.0022918 | 2011 | |
| Clindamycin-modified Triple Antibiotic Nanofibers: A Stain-free Antimicrobial Intracanal Drug Delivery System. | Karczewski A, Feitosa SA, Hamer EI, Pankajakshan D, Gregory RL, Spolnik KJ, Bottino MC. | J Endod | 10.1016/j.joen.2017.08.024 | 2018 | | |
| Piper betle (L): Recent Review of Antibacterial and Antifungal Properties, Safety Profiles, and Commercial Applications. | Nayaka NMDMW, Sasadara MMV, Sanjaya DA, Yuda PESK, Dewi NLKAA, Cahyaningsih E, Hartati R. | Molecules | 10.3390/molecules26082321 | 2021 | | |
| Putative periodontopathic bacteria and herpes viruses interactions in the subgingival plaque of patients with aggressive periodontitis and healthy controls. | Elamin A, Ali RW, Bakken V. | Clin Exp Dent Res | 10.1002/cre2.80 | 2017 | | |
| Phylogeny | Characterization of Mucosa-Associated Microbiota in Matched Cancer and Non-neoplastic Mucosa From Patients With Colorectal Cancer. | Leung PHM, Subramanya R, Mou Q, Lee KT, Islam F, Gopalan V, Lu CT, Lam AK. | Front Microbiol | 10.3389/fmicb.2019.01317 | 2019 | |
| Polybacterial challenge effects on cytokine/chemokine production by macrophages and dendritic cells. | Huang CB, Altimova Y, Strange S, Ebersole JL. | Inflamm Res | 10.1007/s00011-010-0242-0 | 2011 | | |
| Pathogenicity | Efficacy of the de novo-derived antimicrobial peptide WLBU2 against oral bacteria. | Novak KF, Diamond WJ, Kirakodu S, Peyyala R, Anderson KW, Montelaro RC, Mietzner TA. | Antimicrob Agents Chemother | 10.1128/aac.00924-06 | 2007 | |
| Hierarchical micro/nanostructured titanium with balanced actions to bacterial and mammalian cells for dental implants. | Zhu Y, Cao H, Qiao S, Wang M, Gu Y, Luo H, Meng F, Liu X, Lai H. | Int J Nanomedicine | 10.2147/ijn.s92110 | 2015 | | |
| Communication: Antimicrobial Activity of SMAP28 with a Targeting Domain for Porphyromonas gingivalis. | Bratt CL, Kohlgraf KG, Yohnke K, Kummet C, Dawson DV, Brogden KA. | Probiotics Antimicrob Proteins | 10.1007/s12602-009-9028-5 | 2010 | | |
| Supernatants from oral epithelial cells and gingival fibroblasts modulate human immunodeficiency virus type 1 promoter activation induced by periodontopathogens in monocytes/macrophages. | Gonzalez OA, Ebersole JL, Huang CB. | Mol Oral Microbiol | 10.1111/j.2041-1014.2009.00552.x | 2010 | | |
| Antimicrobial activity of n-6, n-7 and n-9 fatty acids and their esters for oral microorganisms. | Huang CB, George B, Ebersole JL. | Arch Oral Biol | 10.1016/j.archoralbio.2010.05.009 | 2010 | | |
| Suppression of T-cell chemokines by Porphyromonas gingivalis. | Jauregui CE, Wang Q, Wright CJ, Takeuchi H, Uriarte SM, Lamont RJ. | Infect Immun | 10.1128/iai.00264-13 | 2013 | | |
| HIV-1 reactivation induced by the periodontal pathogens Fusobacterium nucleatum and Porphyromonas gingivalis involves Toll-like receptor 2 [corrected] and 9 activation in monocytes/macrophages. | Gonzalez OA, Li M, Ebersole JL, Huang CB. | Clin Vaccine Immunol | 10.1128/cvi.00009-10 | 2010 | | |
| Pathogenicity | Reduced Glutathione Mediates Resistance to H2S Toxicity in Oral Streptococci. | Ooi XJ, Tan KS. | Appl Environ Microbiol | 10.1128/aem.03946-15 | 2016 | |
| Genetics | Genome sequence of Fusobacterium nucleatum subspecies polymorphum - a genetically tractable fusobacterium. | Karpathy SE, Qin X, Gioia J, Jiang H, Liu Y, Petrosino JF, Yerrapragada S, Fox GE, Haake SK, Weinstock GM, Highlander SK. | PLoS One | 10.1371/journal.pone.0000659 | 2007 | |
| Enzymology | Characterization and in vitro properties of oral lactobacilli in breastfed infants. | Vestman NR, Timby N, Holgerson PL, Kressirer CA, Claesson R, Domellof M, Ohman C, Tanner AC, Hernell O, Johansson I. | BMC Microbiol | 10.1186/1471-2180-13-193 | 2013 | |
| Metabolism | PerC Manipulates Metabolism and Surface Antigens in Enteropathogenic Escherichia coli. | Mellies JL, Platenkamp A, Osborn J, Ben-Avi L. | Front Cell Infect Microbiol | 10.3389/fcimb.2017.00032 | 2017 | |
| Design, Synthesis, and Characterization of TNP-2198, a Dual-Targeted Rifamycin-Nitroimidazole Conjugate with Potent Activity against Microaerophilic and Anaerobic Bacterial Pathogens. | Ma Z, He S, Yuan Y, Zhuang Z, Liu Y, Wang H, Chen J, Xu X, Ding C, Molodtsov V, Lin W, Robertson GT, Weiss WJ, Pulse M, Nguyen P, Duncan L, Doyle T, Ebright RH, Lynch AS. | J Med Chem | 10.1021/acs.jmedchem.1c02045 | 2022 | | |
| Efficient gene transfer and targeted mutagenesis in Fusobacterium nucleatum. | Kinder Haake S, Yoder S, Gerardo SH. | Plasmid | 10.1016/j.plasmid.2005.06.002 | 2006 | | |
| Proteomics of Streptococcus gordonii within a model developing oral microbial community. | Hendrickson EL, Wang T, Dickinson BC, Whitmore SE, Wright CJ, Lamont RJ, Hackett M. | BMC Microbiol | 10.1186/1471-2180-12-211 | 2012 | | |
| The vaginal microflora in relation to gingivitis. | Persson R, Hitti J, Verhelst R, Vaneechoutte M, Persson R, Hirschi R, Weibel M, Rothen M, Temmerman M, Paul K, Eschenbach D. | BMC Infect Dis | 10.1186/1471-2334-9-6 | 2009 | | |
| Oral bacteria induce a differential activation of human immunodeficiency virus-1 promoter in T cells, macrophages and dendritic cells. | Huang CB, Emerson KA, Gonzalez OA, Ebersole JL. | Oral Microbiol Immunol | 10.1111/j.1399-302x.2009.00533.x | 2009 | | |
| Pathogenicity | Effects of a mouthwash with chlorine dioxide on oral malodor and salivary bacteria: a randomized placebo-controlled 7-day trial. | Shinada K, Ueno M, Konishi C, Takehara S, Yokoyama S, Zaitsu T, Ohnuki M, Wright FA, Kawaguchi Y. | Trials | 10.1186/1745-6215-11-14 | 2010 | |
| Metabolism | Evolution of acetoclastic methanogenesis in Methanosarcina via horizontal gene transfer from cellulolytic Clostridia. | Fournier GP, Gogarten JP. | J Bacteriol | 10.1128/jb.01382-07 | 2008 | |
| An in vitro biofilm model of subgingival plaque. | Walker C, Sedlacek MJ. | Oral Microbiol Immunol | 10.1111/j.1399-302x.2007.00336.x | 2007 | | |
| Pathogenicity | Genetic determinant of intrinsic quinolone resistance in Fusobacterium canifelinum. | Conrads G, Citron DM, Goldstein EJ. | Antimicrob Agents Chemother | 10.1128/aac.49.1.434-437.2005 | 2005 | |
| Metabolism | Regulation of NAMPT in human gingival fibroblasts and biopsies. | Damanaki A, Nokhbehsaim M, Eick S, Gotz W, Winter J, Wahl G, Jager A, Jepsen S, Deschner J. | Mediators Inflamm | 10.1155/2014/912821 | 2014 | |
| Enzymology | Degradation of Incretins and Modulation of Blood Glucose Levels by Periodontopathic Bacterial Dipeptidyl Peptidase 4. | Ohara-Nemoto Y, Nakasato M, Shimoyama Y, Baba TT, Kobayakawa T, Ono T, Yaegashi T, Kimura S, Nemoto TK. | Infect Immun | 10.1128/iai.00277-17 | 2017 | |
| Genetics | Metagenomics-Based Proficiency Test of Smoked Salmon Spiked with a Mock Community. | Sala C, Mordhorst H, Grutzke J, Brinkmann A, Petersen TN, Poulsen C, Cotter PD, Crispie F, Ellis RJ, Castellani G, Amid C, Hakhverdyan M, Guyader SL, Manfreda G, Mossong J, Nitsche A, Ragimbeau C, Schaeffer J, Schlundt J, Tay MYF, Aarestrup FM, Hendriksen RS, Pamp SJ, De Cesare A. | Microorganisms | 10.3390/microorganisms8121861 | 2020 | |
| Injectable MMP-Responsive Nanotube-Modified Gelatin Hydrogel for Dental Infection Ablation. | Ribeiro JS, Bordini EAF, Ferreira JA, Mei L, Dubey N, Fenno JC, Piva E, Lund RG, Schwendeman A, Bottino MC. | ACS Appl Mater Interfaces | 10.1021/acsami.9b22964 | 2020 | | |
| Pathogenicity | Antibacterial activity of sphingoid bases and fatty acids against Gram-positive and Gram-negative bacteria. | Fischer CL, Drake DR, Dawson DV, Blanchette DR, Brogden KA, Wertz PW. | Antimicrob Agents Chemother | 10.1128/aac.05151-11 | 2012 | |
| Cathelicidin LL-37 in Health and Diseases of the Oral Cavity. | Tokajuk J, Deptula P, Piktel E, Daniluk T, Chmielewska S, Wollny T, Wolak P, Fiedoruk K, Bucki R. | Biomedicines | 10.3390/biomedicines10051086 | 2022 | | |
| Metabolism | Toll-like receptor 2 and NALP2 mediate induction of human beta-defensins by fusobacterium nucleatum in gingival epithelial cells. | Ji S, Shin JE, Kim YS, Oh JE, Min BM, Choi Y. | Infect Immun | 10.1128/iai.00449-08 | 2009 | |
| Pathogenic bacterial species associated with endodontic infection evade innate immune control by disabling neutrophils. | Matsui A, Jin JO, Johnston CD, Yamazaki H, Houri-Haddad Y, Rittling SR. | Infect Immun | 10.1128/iai.02256-14 | 2014 | | |
| Autoaggregation response of Fusobacterium nucleatum. | Merritt J, Niu G, Okinaga T, Qi F. | Appl Environ Microbiol | 10.1128/aem.00916-09 | 2009 | | |
| Phylogeny | Phylogenetic and comparative genomics of the family Leptotrichiaceae and introduction of a novel fingerprinting MLVA for Streptobacillus moniliformis. | Eisenberg T, Fawzy A, Nicklas W, Semmler T, Ewers C. | BMC Genomics | 10.1186/s12864-016-3206-0 | 2016 | |
| Genetics | The bioinformatics resource for oral pathogens. | Chen T, Abbey K, Deng WJ, Cheng MC. | Nucleic Acids Res | 10.1093/nar/gki361 | 2005 | |
| Enzymology | A new type of Na(+)-driven ATP synthase membrane rotor with a two-carboxylate ion-coupling motif. | Schulz S, Iglesias-Cans M, Krah A, Yildiz O, Leone V, Matthies D, Cook GM, Faraldo-Gomez JD, Meier T. | PLoS Biol | 10.1371/journal.pbio.1001596 | 2013 | |
| Oxygen and hydrogen peroxide in the early evolution of life on earth: in silico comparative analysis of biochemical pathways. | Slesak I, Slesak H, Kruk J. | Astrobiology | 10.1089/ast.2011.0704 | 2012 | | |
| Pathogenicity | Innate immune response to oral bacteria and the immune evasive characteristics of periodontal pathogens. | Ji S, Choi Y. | J Periodontal Implant Sci | 10.5051/jpis.2013.43.1.3 | 2013 | |
| Enzymology | Highly specific protease-based approach for detection of porphyromonas gingivalis in diagnosis of periodontitis. | Kaman WE, Galassi F, de Soet JJ, Bizzarro S, Loos BG, Veerman EC, van Belkum A, Hays JP, Bikker FJ. | J Clin Microbiol | 10.1128/jcm.05313-11 | 2012 | |
| Metabolism | Novel model for multispecies biofilms that uses rigid gas-permeable lenses. | Peyyala R, Kirakodu SS, Ebersole JL, Novak KF. | Appl Environ Microbiol | 10.1128/aem.00039-11 | 2011 | |
| Metabolism | Mutation of His-157 in the second pore loop drastically reduces the activity of the Synechocystis Ktr-type transporter. | Zulkifli L, Uozumi N. | J Bacteriol | 10.1128/jb.00886-06 | 2006 | |
| Understanding bacterial biofilms: From definition to treatment strategies. | Zhao A, Sun J, Liu Y. | Front Cell Infect Microbiol | 10.3389/fcimb.2023.1137947 | 2023 | | |
| Proteomics of Porphyromonas gingivalis within a model oral microbial community. | Kuboniwa M, Hendrickson EL, Xia Q, Wang T, Xie H, Hackett M, Lamont RJ. | BMC Microbiol | 10.1186/1471-2180-9-98 | 2009 | | |
| Phylogeny | Phylogenetic construction of 17 bacterial phyla by new method and carefully selected orthologs. | Horiike T, Miyata D, Hamada K, Saruhashi S, Shinozawa T, Kumar S, Chakraborty R, Komiyama T, Tateno Y. | Gene | 10.1016/j.gene.2008.10.006 | 2009 | |
| A small molecule, odanacatib, inhibits inflammation and bone loss caused by endodontic disease. | Hao L, Chen W, McConnell M, Zhu Z, Li S, Reddy M, Eleazer PD, Wang M, Li YP. | Infect Immun | 10.1128/iai.01713-14 | 2015 | | |
| Veillonella, Firmicutes: Microbes disguised as Gram negatives. | Vesth T, Ozen A, Andersen SC, Kaas RS, Lukjancenko O, Bohlin J, Nookaew I, Wassenaar TM, Ussery DW. | Stand Genomic Sci | 10.4056/sigs.2981345 | 2013 | | |
| Enzymology | Isolation and characterization of a cyanophage infecting the toxic cyanobacterium Microcystis aeruginosa. | Yoshida T, Takashima Y, Tomaru Y, Shirai Y, Takao Y, Hiroishi S, Nagasaki K. | Appl Environ Microbiol | 10.1128/aem.72.2.1239-1247.2006 | 2006 | |
| Application of bacteriocins in food preservation and infectious disease treatment for humans and livestock: a review. | Ng ZJ, Zarin MA, Lee CK, Tan JS. | RSC Adv | 10.1039/d0ra06161a | 2020 | | |
| Metabolism | Impact of Porphyromonas gingivalis Peptidylarginine Deiminase on Bacterial Biofilm Formation, Epithelial Cell Invasion, and Epithelial Cell Transcriptional Landscape. | Aliko A, Kaminska M, Bergum B, Gawron K, Benedyk M, Lamont RJ, Malicki S, Delaleu N, Potempa J, Mydel P. | Sci Rep | 10.1038/s41598-018-32603-y | 2018 | |
| Inhibiting periapical lesions through AAV-RNAi silencing of cathepsin K. | Gao B, Chen W, Hao L, Zhu G, Feng S, Ci H, Zhou X, Stashenko P, Li YP. | J Dent Res | 10.1177/0022034512468757 | 2013 | | |
| Metabolism | Restriction-modification mediated barriers to exogenous DNA uptake and incorporation employed by Prevotella intermedia. | Johnston CD, Skeete CA, Fomenkov A, Roberts RJ, Rittling SR. | PLoS One | 10.1371/journal.pone.0185234 | 2017 | |
| Metabolism | Acquisition of plasmin activity by Fusobacterium nucleatum subsp. nucleatum and potential contribution to tissue destruction during periodontitis. | Darenfed H, Grenier D, Mayrand D. | Infect Immun | 10.1128/iai.67.12.6439-6444.1999 | 1999 | |
| Pathogenicity | In vitro determination of direct antimicrobial effect of calcium hydroxide. | Estrela C, Pimenta FC, Ito IY, Bammann LL. | J Endod | 10.1016/s0099-2399(98)80205-7 | 1998 | |
| Proteolytic Activities of Oral Bacteria on ProMMP-9 and the Effect of Synthetic Proteinase Inhibitors. | Jie Bao G, Kari K, Tervahartiala T, Sorsa T, Meurman JH. | Open Dent J | 10.2174/1874210600802010096 | 2008 | | |
| Interaction of oral bacteria with gingival epithelial cell multilayers. | Dickinson BC, Moffatt CE, Hagerty D, Whitmore SE, Brown TA, Graves DT, Lamont RJ. | Mol Oral Microbiol | 10.1111/j.2041-1014.2011.00609.x | 2011 | | |
| Use of insertion sequence element IS1126 in a genotyping and transmission study of Porphyromonas gingivalis. | Park OJ, Min KM, Choe SJ, Choi BK, Kim KK. | J Clin Microbiol | 10.1128/jcm.42.2.535-541.2004 | 2004 | | |
| Development and characterization of novel ZnO-loaded electrospun membranes for periodontal regeneration. | Munchow EA, Albuquerque MT, Zero B, Kamocki K, Piva E, Gregory RL, Bottino MC. | Dent Mater | 10.1016/j.dental.2015.06.004 | 2015 | | |
| Artificial neural networks for the diagnosis of aggressive periodontitis trained by immunologic parameters. | Papantonopoulos G, Takahashi K, Bountis T, Loos BG. | PLoS One | 10.1371/journal.pone.0089757 | 2014 | | |
| Metabolism | The genome sequence of Methanosphaera stadtmanae reveals why this human intestinal archaeon is restricted to methanol and H2 for methane formation and ATP synthesis. | Fricke WF, Seedorf H, Henne A, Kruer M, Liesegang H, Hedderich R, Gottschalk G, Thauer RK. | J Bacteriol | 10.1128/jb.188.2.642-658.2006 | 2006 | |
| Metabolism | Streptococcus gordonii programs epithelial cells to resist ZEB2 induction by Porphyromonas gingivalis. | Ohshima J, Wang Q, Fitzsimonds ZR, Miller DP, Sztukowska MN, Jung YJ, Hayashi M, Whiteley M, Lamont RJ. | Proc Natl Acad Sci U S A | 10.1073/pnas.1900101116 | 2019 | |
| Metabolism | Black Tea Extract and Its Theaflavin Derivatives Inhibit the Growth of Periodontopathogens and Modulate Interleukin-8 and beta-Defensin Secretion in Oral Epithelial Cells. | Lombardo Bedran TB, Morin MP, Palomari Spolidorio D, Grenier D. | PLoS One | 10.1371/journal.pone.0143158 | 2015 | |
| Phylogeny | Are putative periodontal pathogens reliable diagnostic markers? | Riep B, Edesi-Neuss L, Claessen F, Skarabis H, Ehmke B, Flemmig TF, Bernimoulin JP, Gobel UB, Moter A. | J Clin Microbiol | 10.1128/jcm.01387-08 | 2009 | |
| Enzymology | Polymerase chain reaction-amplified nonradioactive probes for identification of Fusobacterium nucleatum. | Bolstad AI, Jensen HB. | J Clin Microbiol | 10.1128/jcm.31.3.528-532.1993 | 1993 | |
| Dysbiotic oral microbiota and infected salivary glands in Sjögren's syndrome. | Alam J, Lee A, Lee J, Kwon DI, Park HK, Park JH, Jeon S, Baek K, Lee J, Park SH, Choi Y. | PLoS One | 10.1371/journal.pone.0230667 | 2020 | | |
| RNA interference-mediated silencing of Atp6i prevents both periapical bone erosion and inflammation in the mouse model of endodontic disease. | Ma J, Chen W, Zhang L, Tucker B, Zhu G, Sasaki H, Hao L, Wang L, Ci H, Jiang H, Stashenko P, Li YP. | Infect Immun | 10.1128/iai.00756-12 | 2013 | | |
| Metabolism | Enterotoxigenic Bacteroides fragilis induces the stemness in colorectal cancer via upregulating histone demethylase JMJD2B. | Liu QQ, Li CM, Fu LN, Wang HL, Tan J, Wang YQ, Sun DF, Gao QY, Chen YX, Fang JY. | Gut Microbes | 10.1080/19490976.2020.1788900 | 2020 | |
| Subgingival microbiota in adult Down syndrome periodontitis. | Khocht A, Yaskell T, Janal M, Turner BF, Rams TE, Haffajee AD, Socransky SS. | J Periodontal Res | 10.1111/j.1600-0765.2011.01459.x | 2012 | | |
| Genetics | Microbial community profiling of human saliva using shotgun metagenomic sequencing. | Hasan NA, Young BA, Minard-Smith AT, Saeed K, Li H, Heizer EM, McMillan NJ, Isom R, Abdullah AS, Bornman DM, Faith SA, Choi SY, Dickens ML, Cebula TA, Colwell RR. | PLoS One | 10.1371/journal.pone.0097699 | 2014 | |
| Genetics | Mash Screen: high-throughput sequence containment estimation for genome discovery. | Ondov BD, Starrett GJ, Sappington A, Kostic A, Koren S, Buck CB, Phillippy AM. | Genome Biol | 10.1186/s13059-019-1841-x | 2019 | |
| In Vitro-Activity of Er:YAG Laser in Comparison with other Treatment Modalities on Biofilm Ablation from Implant and Tooth Surfaces. | Eick S, Meier I, Spoerle F, Bender P, Aoki A, Izumi Y, Salvi GE, Sculean A. | PLoS One | 10.1371/journal.pone.0171086 | 2017 | | |
| Pathogenicity | The oral commensal, Streptococcus gordonii, synergizes with Tat protein to induce HIV-1 promoter activation in monocytes/macrophages. | Gonzalez OA, Ebersole JL, Huang CB. | Cell Immunol | 10.1016/j.cellimm.2011.03.008 | 2011 | |
| Metabolism | Interplay of protease-activated receptors and NOD pattern recognition receptors in epithelial innate immune responses to bacteria. | Chung WO, An JY, Yin L, Hacker BM, Rohani MG, Dommisch H, DiJulio DH. | Immunol Lett | 10.1016/j.imlet.2010.02.006 | 2010 | |
| Pathogenicity | In Vitro and In Vivo Activity of Peptidomimetic Compounds That Target the Periodontal Pathogen Porphyromonas gingivalis. | Tan J, Patil PC, Luzzio FA, Demuth DR. | Antimicrob Agents Chemother | 10.1128/aac.00400-18 | 2018 | |
| Optimizing qPCR for the Quantification of Periodontal Pathogens in a Complex Plaque Biofilm. | Kirakodu SS, Govindaswami M, Novak MJ, Ebersole JL, Novak KF. | Open Dent J | 10.2174/1874210600802010049 | 2008 | | |
| Metabolism | Differential utilization of nuclear factor-kappaB signaling pathways for gingival epithelial cell responses to oral commensal and pathogenic bacteria. | Chung WO, Dale BA. | Oral Microbiol Immunol | 10.1111/j.1399-302x.2007.00398.x | 2008 | |
| Pathogenicity | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. | Tanaka K, Mikamo H, Nakao K, Ichiishi T, Goto T, Yamagishi Y, Watanabe K. | Antimicrob Agents Chemother | 10.1128/aac.00595-08 | 2009 | |
| Pathogenic microbes and community service through manipulation of innate immunity. | Hajishengallis G, Krauss JL, Liang S, McIntosh ML, Lambris JD. | Adv Exp Med Biol | 10.1007/978-1-4614-0106-3_5 | 2012 | | |
| Molecular analysis of the diversity of vaginal microbiota associated with bacterial vaginosis. | Ling Z, Kong J, Liu F, Zhu H, Chen X, Wang Y, Li L, Nelson KE, Xia Y, Xiang C. | BMC Genomics | 10.1186/1471-2164-11-488 | 2010 | | |
| Pathogenicity | Beneficial effects of adiponectin on periodontal ligament cells under normal and regenerative conditions. | Nokhbehsaim M, Keser S, Nogueira AV, Cirelli JA, Jepsen S, Jager A, Eick S, Deschner J. | J Diabetes Res | 10.1155/2014/796565 | 2014 | |
| Pathogenicity | Antimicrobial evaluation of diterpenes from Copaifera langsdorffii oleoresin against periodontal anaerobic bacteria. | Souza AB, de Souza MG, Moreira MA, Moreira MR, Furtado NA, Martins CH, Bastos JK, dos Santos RA, Heleno VC, Ambrosio SR, Veneziani RC. | Molecules | 10.3390/molecules16119611 | 2011 | |
| Macrophage polarization in response to oral commensals and pathogens. | Huang CB, Alimova Y, Ebersole JL. | Pathog Dis | 10.1093/femspd/ftw011 | 2016 | | |
| Pathogenicity | In vitro antimicrobial activity of razupenem (SMP-601, PTZ601) against anaerobic bacteria. | Tran CM, Tanaka K, Yamagishi Y, Goto T, Mikamo H, Watanabe K. | Antimicrob Agents Chemother | 10.1128/aac.01038-10 | 2011 | |
| Quantitative and qualitative analysis of microorganisms in root-filled teeth with persistent infection: Monitoring of the endodontic retreatment. | Endo MS, Ferraz CCR, Zaia AA, Almeida JFA, Gomes BPFA. | Eur J Dent | 10.4103/1305-7456.115414 | 2013 | | |
| Gingival epithelial cell transcriptional responses to commensal and opportunistic oral microbial species. | Hasegawa Y, Mans JJ, Mao S, Lopez MC, Baker HV, Handfield M, Lamont RJ. | Infect Immun | 10.1128/iai.01957-06 | 2007 | | |
| Co-localized or randomly distributed? Pair cross correlation of in vivo grown subgingival biofilm bacteria quantified by digital image analysis. | Schillinger C, Petrich A, Lux R, Riep B, Kikhney J, Friedmann A, Wolinsky LE, Gobel UB, Daims H, Moter A. | PLoS One | 10.1371/journal.pone.0037583 | 2012 | | |
| Metabolism | Differential and coordinated expression of defensins and cytokines by gingival epithelial cells and dendritic cells in response to oral bacteria. | Yin L, Chino T, Horst OV, Hacker BM, Clark EA, Dale BA, Chung WO. | BMC Immunol | 10.1186/1471-2172-11-37 | 2010 | |
| Effect of bacteria on the wound healing behavior of oral epithelial cells. | Bhattacharya R, Xu F, Dong G, Li S, Tian C, Ponugoti B, Graves DT. | PLoS One | 10.1371/journal.pone.0089475 | 2014 | | |
| Pathogenicity | Differential effects of periopathogens on host protease inhibitors SLPI, elafin, SCCA1, and SCCA2. | Yin L, Swanson B, An J, Hacker BM, Silverman GA, Dale BA, Chung WO. | J Oral Microbiol | 10.3402/jom.v2i0.5070 | 2010 | |
| Molecular sensing by the aptamer domain of the FMN riboswitch: a general model for ligand binding by conformational selection. | Vicens Q, Mondragon E, Batey RT. | Nucleic Acids Res | 10.1093/nar/gkr565 | 2011 | | |
| Metabolism | Mobilization and prevalence of a Fusobacterial plasmid. | Claypool BM, Yoder SC, Citron DM, Finegold SM, Goldstein EJ, Haake SK. | Plasmid | 10.1016/j.plasmid.2009.09.001 | 2010 | |
| Enzymology | Short-chain fatty acids from periodontal pathogens suppress histone deacetylases, EZH2, and SUV39H1 to promote Kaposi's sarcoma-associated herpesvirus replication. | Yu X, Shahir AM, Sha J, Feng Z, Eapen B, Nithianantham S, Das B, Karn J, Weinberg A, Bissada NF, Ye F. | J Virol | 10.1128/jvi.03326-13 | 2014 | |
| Functional constituents of wild and cultivated Goji (L. barbarum L.) leaves: phytochemical characterization, biological profile, and computational studies. | Mocan A, Zengin G, Simirgiotis M, Schafberg M, Mollica A, Vodnar DC, Crisan G, Rohn S. | J Enzyme Inhib Med Chem | 10.1080/14756366.2016.1243535 | 2017 | | |
| Metabolism | Identification of the binding domain of Streptococcus oralis glyceraldehyde-3-phosphate dehydrogenase for Porphyromonas gingivalis major fimbriae. | Nagata H, Iwasaki M, Maeda K, Kuboniwa M, Hashino E, Toe M, Minamino N, Kuwahara H, Shizukuishi S. | Infect Immun | 10.1128/iai.00439-09 | 2009 | |
| Phylogeny | Evolutionary relationships of Fusobacterium nucleatum based on phylogenetic analysis and comparative genomics. | Mira A, Pushker R, Legault BA, Moreira D, Rodriguez-Valera F. | BMC Evol Biol | 10.1186/1471-2148-4-50 | 2004 | |
| Metabolism | Dentilisin activity affects the organization of the outer sheath of Treponema denticola. | Ishihara K, Kuramitsu HK, Miura T, Okuda K. | J Bacteriol | 10.1128/jb.180.15.3837-3844.1998 | 1998 | |
| Taxonomy, biology, and periodontal aspects of Fusobacterium nucleatum. | Bolstad AI, Jensen HB, Bakken V. | Clin Microbiol Rev | 10.1128/cmr.9.1.55 | 1996 | | |
| Metabolism | Role of Porphyromonas gingivalis SerB in gingival epithelial cell cytoskeletal remodeling and cytokine production. | Hasegawa Y, Tribble GD, Baker HV, Mans JJ, Handfield M, Lamont RJ. | Infect Immun | 10.1128/iai.00156-08 | 2008 | |
| Metabolism | Elevated CD14 (Cluster of Differentiation 14) and Toll-Like Receptor (TLR) 4 Signaling Deteriorate Periapical Inflammation in TLR2 Deficient Mice. | Rider D, Furusho H, Xu S, Trachtenberg AJ, Kuo WP, Hirai K, Susa M, Bahammam L, Stashenko P, Fujimura A, Sasaki H. | Anat Rec (Hoboken) | 10.1002/ar.23383 | 2016 | |
| Photodynamic treatment of endodontic polymicrobial infection in vitro. | Fimple JL, Fontana CR, Foschi F, Ruggiero K, Song X, Pagonis TC, Tanner AC, Kent R, Doukas AG, Stashenko PP, Soukos NS. | J Endod | 10.1016/j.joen.2008.03.011 | 2008 | | |
| Filament formation of Fusobacterium nucleatum cells induced by mecillinam. | Onoe T, Umemoto T, Sagawa H, Suginaka H. | Antimicrob Agents Chemother | 10.1128/aac.19.3.487 | 1981 | | |
| Treponema denticola suppresses expression of human {beta}-defensin-3 in gingival epithelial cells through inhibition of the toll-like receptor 2 axis. | Shin JE, Kim YS, Oh JE, Min BM, Choi Y. | Infect Immun | 10.1128/iai.00808-09 | 2010 | | |
| Genetics | DciA is an ancestral replicative helicase operator essential for bacterial replication initiation. | Brezellec P, Vallet-Gely I, Possoz C, Quevillon-Cheruel S, Ferat JL. | Nat Commun | 10.1038/ncomms13271 | 2016 | |
| Metabolism | Activation of hypoxia-inducible factor 1 attenuates periapical inflammation and bone loss. | Hirai K, Furusho H, Hirota K, Sasaki H. | Int J Oral Sci | 10.1038/s41368-018-0015-0 | 2018 | |
| Enzymology | Comparative analyses imply that the enigmatic Sigma factor 54 is a central controller of the bacterial exterior. | Francke C, Groot Kormelink T, Hagemeijer Y, Overmars L, Sluijter V, Moezelaar R, Siezen RJ. | BMC Genomics | 10.1186/1471-2164-12-385 | 2011 | |
| Hemagglutinating activity of lipopolysaccharides from subgingival plaque bacteria. | Okuda K, Kato T. | Infect Immun | 10.1128/iai.55.12.3192-3196.1987 | 1987 | | |
| Metabolism | Cariogenic actinomyces identified with a beta-glucosidase-dependent green color reaction to Gardenia jasminoides extract. | Chen L, Ma L, Park NH, Shi W. | J Clin Microbiol | 10.1128/jcm.39.8.3009-3012.2001 | 2001 | |
| Conservation of coevolving protein interfaces bridges prokaryote-eukaryote homologies in the twilight zone. | Rodriguez-Rivas J, Marsili S, Juan D, Valencia A. | Proc Natl Acad Sci U S A | 10.1073/pnas.1611861114 | 2016 | | |
| Filifactor alocis--involvement in periodontal biofilms. | Schlafer S, Riep B, Griffen AL, Petrich A, Hubner J, Berning M, Friedmann A, Gobel UB, Moter A. | BMC Microbiol | 10.1186/1471-2180-10-66 | 2010 | | |
| Microbial Biofilm Decontamination on Dental Implant Surfaces: A Mini Review. | Dhaliwal JS, Abd Rahman NA, Ming LC, Dhaliwal SKS, Knights J, Albuquerque Junior RF. | Front Cell Infect Microbiol | 10.3389/fcimb.2021.736186 | 2021 | | |
| Pathogenicity | Antimicrobial Activities of Methanol, Ethanol and Supercritical CO2 Extracts of Philippine Piper betle L. on Clinical Isolates of Gram Positive and Gram Negative Bacteria with Transferable Multiple Drug Resistance. | Valle DL, Cabrera EC, Puzon JJ, Rivera WL. | PLoS One | 10.1371/journal.pone.0146349 | 2016 | |
| Pathogenicity | Novel riboswitch-binding flavin analog that protects mice against Clostridium difficile infection without inhibiting cecal flora. | Blount KF, Megyola C, Plummer M, Osterman D, O'Connell T, Aristoff P, Quinn C, Chrusciel RA, Poel TJ, Schostarez HJ, Stewart CA, Walker DP, Wuts PG, Breaker RR. | Antimicrob Agents Chemother | 10.1128/aac.01282-15 | 2015 | |
| Leptin effects on the regenerative capacity of human periodontal cells. | Nokhbehsaim M, Keser S, Nogueira AV, Jager A, Jepsen S, Cirelli JA, Bourauel C, Eick S, Deschner J. | Int J Endocrinol | 10.1155/2014/180304 | 2014 | | |
| Pathogenicity | In vaginal fluid, bacteria associated with bacterial vaginosis can be suppressed with lactic acid but not hydrogen peroxide. | O'Hanlon DE, Moench TR, Cone RA. | BMC Infect Dis | 10.1186/1471-2334-11-200 | 2011 | |
| Metabolism | Lifestyle, dietary factors, and antibody levels to oral bacteria in cancer-free participants of a European cohort study. | Michaud DS, Izard J, Rubin Z, Johansson I, Weiderpass E, Tjonneland A, Olsen A, Overvad K, Boutron-Ruault MC, Clavel-Chapelon F, Dossus L, Kaaks R, Katzke VA, Boeing H, Foerster J, Trichopoulou A, Naska A, Ziara G, Vineis P, Grioni S, Palli D, Tumino R, Mattiello A, Peeters PH, Siersema PD, Barricarte A, Huerta JM, Molina-Montes E, Dorronsoro M, Quiros JR, Duell EJ, Ohlsson B, Jeppsson B, Johansson A, Lif P, Khaw KT, Wareham N, Travis RC, Key TJ, Freisling H, Duarte-Salles T, Stepien M, Riboli E, Bueno-de-Mesquita HB. | Cancer Causes Control | 10.1007/s10552-013-0265-2 | 2013 | |
| Enzymology | Genetic profiling of the oral microbiota associated with severe early-childhood caries. | Li Y, Ge Y, Saxena D, Caufield PW. | J Clin Microbiol | 10.1128/jcm.01622-06 | 2007 | |
| Induction of apoptotic cell death in peripheral blood mononuclear and polymorphonuclear cells by an oral bacterium, Fusobacterium nucleatum. | Jewett A, Hume WR, Le H, Huynh TN, Han YW, Cheng G, Shi W. | Infect Immun | 10.1128/iai.68.4.1893-1898.2000 | 2000 | | |
| Metabolism | Early Cytokine Response to Infection with Pathogenic vs Non-Pathogenic Organisms in a Mouse Model of Endodontic Infection. | Matsui A, Stephens D, Kantarci A, Rittling SR. | PLoS One | 10.1371/journal.pone.0132752 | 2015 | |
| The OxyR homologue in Tannerella forsythia regulates expression of oxidative stress responses and biofilm formation. | Honma K, Mishima E, Inagaki S, Sharma A. | Microbiology (Reading) | 10.1099/mic.0.027920-0 | 2009 | | |
| A Biofilm Pocket Model to Evaluate Different Non-Surgical Periodontal Treatment Modalities in Terms of Biofilm Removal and Reformation, Surface Alterations and Attachment of Periodontal Ligament Fibroblasts. | Hagi TT, Klemensberger S, Bereiter R, Nietzsche S, Cosgarea R, Flury S, Lussi A, Sculean A, Eick S. | PLoS One | 10.1371/journal.pone.0131056 | 2015 | | |
| Glyceraldehyde-3-phosphate dehydrogenase of Streptococcus oralis functions as a coadhesin for Porphyromonas gingivalis major fimbriae. | Maeda K, Nagata H, Yamamoto Y, Tanaka M, Tanaka J, Minamino N, Shizukuishi S. | Infect Immun | 10.1128/iai.72.3.1341-1348.2004 | 2004 | | |
| Metabolism | Noncanonical activation of beta-catenin by Porphyromonas gingivalis. | Zhou Y, Sztukowska M, Wang Q, Inaba H, Potempa J, Scott DA, Wang H, Lamont RJ. | Infect Immun | 10.1128/iai.00302-15 | 2015 | |
| Biological effects of a root conditioning agent for dentin surface modification in vitro. | Lee JY, Seol YJ, Park JR, Park YJ, Chung CP. | J Periodontal Implant Sci | 10.5051/jpis.2010.40.6.257 | 2010 | | |
| Maresin 1 Biosynthesis and Proresolving Anti-infective Functions with Human-Localized Aggressive Periodontitis Leukocytes. | Wang CW, Colas RA, Dalli J, Arnardottir HH, Nguyen D, Hasturk H, Chiang N, Van Dyke TE, Serhan CN. | Infect Immun | 10.1128/iai.01131-15 | 2015 | | |
| Pathogenicity | Antibacterial activity of the human host defence peptide LL-37 and selected synthetic cationic lipids against bacteria associated with oral and upper respiratory tract infections. | Leszczynska K, Namiot D, Byfield FJ, Cruz K, Zendzian-Piotrowska M, Fein DE, Savage PB, Diamond S, McCulloch CA, Janmey PA, Bucki R. | J Antimicrob Chemother | 10.1093/jac/dks434 | 2013 | |
| Comparison of three transport systems (Starplex StarSwab II, the new Copan Vi-Pak Amies Agar Gel collection and transport swabs, and BBL Port-A-Cul) for maintenance of anaerobic and fastidious aerobic organisms. | Hindiyeh M, Acevedo V, Carroll KC. | J Clin Microbiol | 10.1128/jcm.39.1.377-380.2001 | 2001 | | |
| In search of RNase P RNA from microbial genomes. | Li Y, Altman S. | RNA | 10.1261/rna.7970404 | 2004 | | |
| IL-17 receptor A signaling is protective in infection-stimulated periapical bone destruction. | AlShwaimi E, Berggreen E, Furusho H, Rossall JC, Dobeck J, Yoganathan S, Stashenko P, Sasaki H. | J Immunol | 10.4049/jimmunol.1202194 | 2013 | | |
| Phylogeny | Evolutionary analyses of non-genealogical bonds produced by introgressive descent. | Bapteste E, Lopez P, Bouchard F, Baquero F, McInerney JO, Burian RM. | Proc Natl Acad Sci U S A | 10.1073/pnas.1206541109 | 2012 | |
| Serum antibodies to Porphyromonas gingivalis chaperone HtpG predict health in periodontitis susceptible patients. | Shelburne CE, Shelburne PS, Dhople VM, Sweier DG, Giannobile WV, Kinney JS, Coulter WA, Mullally BH, Lopatin DE. | PLoS One | 10.1371/journal.pone.0001984 | 2008 | | |
| Humoral immune responses to S-layer-like proteins of Bacteroides forsythus. | Yoneda M, Hirofuji T, Motooka N, Nozoe K, Shigenaga K, Anan H, Miura M, Kabashima H, Matsumoto A, Maeda K. | Clin Diagn Lab Immunol | 10.1128/cdli.10.3.383-387.2003 | 2003 | | |
| Inducible expression of human beta-defensin 2 by Fusobacterium nucleatum in oral epithelial cells: multiple signaling pathways and role of commensal bacteria in innate immunity and the epithelial barrier. | Krisanaprakornkit S, Kimball JR, Weinberg A, Darveau RP, Bainbridge BW, Dale BA. | Infect Immun | 10.1128/iai.68.5.2907-2915.2000 | 2000 | | |
| Metabolism | Metabolic Modeling of Cystic Fibrosis Airway Communities Predicts Mechanisms of Pathogen Dominance. | Henson MA, Orazi G, Phalak P, O'Toole GA. | mSystems | 10.1128/msystems.00026-19 | 2019 | |
| Enzymology | Cultivation of a Synergistetes strain representing a previously uncultivated lineage. | Vartoukian SR, Palmer RM, Wade WG. | Environ Microbiol | 10.1111/j.1462-2920.2009.02135.x | 2010 | |
| Comparison of the Copan ESwab system with two Amies agar swab transport systems for maintenance of microorganism viability. | Van Horn KG, Audette CD, Sebeck D, Tucker KA. | J Clin Microbiol | 10.1128/jcm.02047-07 | 2008 | | |
| Whole-genome mutational biases in bacteria. | Lind PA, Andersson DI. | Proc Natl Acad Sci U S A | 10.1073/pnas.0804445105 | 2008 | | |
| Phylogeny | Annotation-based inference of transporter function. | Lee TJ, Paulsen I, Karp P. | Bioinformatics | 10.1093/bioinformatics/btn180 | 2008 | |
| Pathogenicity | In vitro antianaerobic activity of DX-619, a new des-fluoro(6) quinolone. | Tanaka K, Mikamo H, Nakao K, Watanabe K. | Antimicrob Agents Chemother | 10.1128/aac.00639-06 | 2006 | |
| Antimicrobial barrier of an in vitro oral epithelial model. | Kimball JR, Nittayananta W, Klausner M, Chung WO, Dale BA. | Arch Oral Biol | 10.1016/j.archoralbio.2006.05.007 | 2006 | | |
| Metabolism | Insights into the evolution of sialic acid catabolism among bacteria. | Almagro-Moreno S, Boyd EF. | BMC Evol Biol | 10.1186/1471-2148-9-118 | 2009 | |
| Genetics | Protective role of the vulture facial skin and gut microbiomes aid adaptation to scavenging. | Zepeda Mendoza ML, Roggenbuck M, Manzano Vargas K, Hansen LH, Brunak S, Gilbert MTP, Sicheritz-Ponten T. | Acta Vet Scand | 10.1186/s13028-018-0415-3 | 2018 | |
| Functional Promiscuity of Homologues of the Bacterial ArsA ATPases. | Castillo R, Saier MH. | Int J Microbiol | 10.1155/2010/187373 | 2010 | | |
| Genetic characterization of the Bifidobacterium breve UCC 2003 hrcA locus. | Ventura M, Canchaya C, Bernini V, Del Casale A, Dellaglio F, Neviani E, Fitzgerald GF, van Sinderen D. | Appl Environ Microbiol | 10.1128/aem.71.12.8998-9007.2005 | 2005 | | |
| Metabolism | Toll-like receptor 4-deficient mice have reduced bone destruction following mixed anaerobic infection. | Hou L, Sasaki H, Stashenko P. | Infect Immun | 10.1128/iai.68.8.4681-4687.2000 | 2000 | |
| Enzymology | BactQuant: an enhanced broad-coverage bacterial quantitative real-time PCR assay. | Liu CM, Aziz M, Kachur S, Hsueh PR, Huang YT, Keim P, Price LB. | BMC Microbiol | 10.1186/1471-2180-12-56 | 2012 | |
| Phylogeny | Comparative genomic analyses of the bacterial phosphotransferase system. | Barabote RD, Saier MH. | Microbiol Mol Biol Rev | 10.1128/mmbr.69.4.608-634.2005 | 2005 | |
| Fast algorithms for computing sequence distances by exhaustive substring composition. | Apostolico A, Denas O. | Algorithms Mol Biol | 10.1186/1748-7188-3-13 | 2008 | | |
| Genetics | Genome-wide gene order distances support clustering the gram-positive bacteria. | House CH, Pellegrini M, Fitz-Gibbon ST. | Front Microbiol | 10.3389/fmicb.2014.00785 | 2014 | |
| Metabolism | Ethanolamine utilization in Vibrio alginolyticus. | Khatri N, Khatri I, Subramanian S, Raychaudhuri S. | Biol Direct | 10.1186/1745-6150-7-45 | 2012 | |
| Metabolism | GEM System: automatic prototyping of cell-wide metabolic pathway models from genomes. | Arakawa K, Yamada Y, Shinoda K, Nakayama Y, Tomita M. | BMC Bioinformatics | 10.1186/1471-2105-7-168 | 2006 | |
| Interleukin-6 deficiency increases inflammatory bone destruction. | Balto K, Sasaki H, Stashenko P. | Infect Immun | 10.1128/iai.69.2.744-750.2001 | 2001 | | |
| Metabolism | CoMetGeNe: mining conserved neighborhood patterns in metabolic and genomic contexts. | Zaharia A, Labedan B, Froidevaux C, Denise A. | BMC Bioinformatics | 10.1186/s12859-018-2542-2 | 2019 | |
| Phylogeny | PCR assay for species-specific identification of Bacteroides thetaiotaomicron. | Teng LJ, Hsueh PR, Tsai JC, Chiang FL, Chen CY, Ho SW, Luh KT. | J Clin Microbiol | 10.1128/jcm.38.4.1672-1675.2000 | 2000 | |
| QC-Chain: fast and holistic quality control method for next-generation sequencing data. | Zhou Q, Su X, Wang A, Xu J, Ning K. | PLoS One | 10.1371/journal.pone.0060234 | 2013 | | |
| High-density microarray of small-subunit ribosomal DNA probes. | Wilson KH, Wilson WJ, Radosevich JL, DeSantis TZ, Viswanathan VS, Kuczmarski TA, Andersen GL. | Appl Environ Microbiol | 10.1128/aem.68.5.2535-2541.2002 | 2002 | | |
| Increased susceptibility of RAG-2 SCID mice to dissemination of endodontic infections. | Teles R, Wang CY, Stashenko P. | Infect Immun | 10.1128/iai.65.9.3781-3787.1997 | 1997 | | |
| Enzymology | Molecular evolution of urea amidolyase and urea carboxylase in fungi. | Strope PK, Nickerson KW, Harris SD, Moriyama EN. | BMC Evol Biol | 10.1186/1471-2148-11-80 | 2011 | |
| Phylogeny | Use of PCR and sodium dodecyl sulfate-polyacrylamide gel electrophoresis techniques for differentiation of Prevotella intermedia sensu stricto and Prevotella nigrescens. | Premaraj T, Kato N, Fukui K, Kato H, Watanabe K. | J Clin Microbiol | 10.1128/jcm.37.4.1057-1061.1999 | 1999 | |
| Metagenomic analysis of the medicinal leech gut microbiota. | Maltz MA, Bomar L, Lapierre P, Morrison HG, McClure EA, Sogin ML, Graf J. | Front Microbiol | 10.3389/fmicb.2014.00151 | 2014 | | |
| Subgingival biofilm formation. | Kuboniwa M, Lamont RJ. | Periodontol 2000 | 10.1111/j.1600-0757.2009.00311.x | 2010 | | |
| Genetics | Porphyromonas gingivalis invades human trophoblasts and inhibits proliferation by inducing G1 arrest and apoptosis. | Inaba H, Kuboniwa M, Bainbridge B, Yilmaz O, Katz J, Shiverick KT, Amano A, Lamont RJ. | Cell Microbiol | 10.1111/j.1462-5822.2009.01344.x | 2009 | |
| B-Cell deficiency predisposes mice to disseminating anaerobic infections: protection by passive antibody transfer. | Hou L, Sasakj H, Stashenko P. | Infect Immun | 10.1128/iai.68.10.5645-5651.2000 | 2000 | | |
| Enzymology | Quantitative analysis of diverse Lactobacillus species present in advanced dental caries. | Byun R, Nadkarni MA, Chhour KL, Martin FE, Jacques NA, Hunter N. | J Clin Microbiol | 10.1128/jcm.42.7.3128-3136.2004 | 2004 | |
| Phylogeny | Diversity and morphology of members of the phylum "synergistetes" in periodontal health and disease. | Vartoukian SR, Palmer RM, Wade WG. | Appl Environ Microbiol | 10.1128/aem.02763-08 | 2009 | |
| Metabolism | Prokaryote phylogeny based on ribosomal proteins and aminoacyl tRNA synthetases by using the compositional distance approach. | Wei H, Qi J, Hao B. | Sci China C Life Sci | 10.1360/03yc0137 | 2004 | |
| Genetics | Comparative genomics of gene-family size in closely related bacteria. | Pushker R, Mira A, Rodriguez-Valera F. | Genome Biol | 10.1186/gb-2004-5-4-r27 | 2004 | |
| Pathogenicity | Activity of a peptidyl prodrug, alafosfalin, against anaerobic bacteria. | Grappel SF, Giovenella AJ, Nisbet LJ. | Antimicrob Agents Chemother | 10.1128/aac.27.6.961 | 1985 | |
| Identification by subtractive hybridization of a novel insertion sequence specific for virulent strains of Porphyromonas gingivalis. | Sawada K, Kokeguchi S, Hongyo H, Sawada S, Miyamoto M, Maeda H, Nishimura F, Takashiba S, Murayama Y. | Infect Immun | 10.1128/iai.67.11.5621-5625.1999 | 1999 | | |
| Pathogenicity | Induction of {beta}-defensin resistance in the oral anaerobe Porphyromonas gingivalis. | Shelburne CE, Coulter WA, Olguin D, Lantz MS, Lopatin DE. | Antimicrob Agents Chemother | 10.1128/aac.49.1.183-187.2005 | 2005 | |
| Metabolism | Molecular characterization and substrate preference of a polycyclic aromatic hydrocarbon dioxygenase from Cycloclasticus sp. strain A5. | Kasai Y, Shindo K, Harayama S, Misawa N. | Appl Environ Microbiol | 10.1128/aem.69.11.6688-6697.2003 | 2003 | |
| Genetics | Operon prediction for sequenced bacterial genomes without experimental information. | Bergman NH, Passalacqua KD, Hanna PC, Qin ZS. | Appl Environ Microbiol | 10.1128/aem.01686-06 | 2007 | |
| Plasma antibodies to oral bacteria and risk of pancreatic cancer in a large European prospective cohort study. | Michaud DS, Izard J, Wilhelm-Benartzi CS, You DH, Grote VA, Tjonneland A, Dahm CC, Overvad K, Jenab M, Fedirko V, Boutron-Ruault MC, Clavel-Chapelon F, Racine A, Kaaks R, Boeing H, Foerster J, Trichopoulou A, Lagiou P, Trichopoulos D, Sacerdote C, Sieri S, Palli D, Tumino R, Panico S, Siersema PD, Peeters PH, Lund E, Barricarte A, Huerta JM, Molina-Montes E, Dorronsoro M, Quiros JR, Duell EJ, Ye W, Sund M, Lindkvist B, Johansen D, Khaw KT, Wareham N, Travis RC, Vineis P, Bueno-de-Mesquita HB, Riboli E. | Gut | 10.1136/gutjnl-2012-303006 | 2013 | | |
| Metabolism | Co-evolution of tRNA 3' trailer sequences with 3' processing enzymes in bacteria. | Li Z, Gong X, Joshi VH, Li M. | RNA | 10.1261/rna.7287505 | 2005 | |
| Phylogeny | Uncultivated phylotypes and newly named species associated with primary and persistent endodontic infections. | Siqueira JF, Rocas IN. | J Clin Microbiol | 10.1128/jcm.43.7.3314-3319.2005 | 2005 | |
| Metabolism | Fidaxomicin preserves the intestinal microbiome during and after treatment of Clostridium difficile infection (CDI) and reduces both toxin reexpression and recurrence of CDI. | Louie TJ, Cannon K, Byrne B, Emery J, Ward L, Eyben M, Krulicki W. | Clin Infect Dis | 10.1093/cid/cis338 | 2012 | |
| Enzymology | Localization of propionibacterium acnes in granulomas supports a possible etiologic link between sarcoidosis and the bacterium. | Negi M, Takemura T, Guzman J, Uchida K, Furukawa A, Suzuki Y, Iida T, Ishige I, Minami J, Yamada T, Kawachi H, Costabel U, Eishi Y. | Mod Pathol | 10.1038/modpathol.2012.80 | 2012 | |
| Enzymology | Isolation of a major cell envelope protein from Fusobacterium nucleatum. | DiRienzo JM, Rosan B. | Infect Immun | 10.1128/iai.44.2.386-393.1984 | 1984 | |
| Pathogenicity | In vitro activity of FK037, a new parenteral cephalosporin, against anaerobic bacteria. | Kato N, Kato H, Tanaka Y, Bando K, Watanabe K, Ueno K. | Antimicrob Agents Chemother | 10.1128/aac.37.5.957 | 1993 | |
| Nutraceuticals in Periodontal Health: A Systematic Review on the Role of Vitamins in Periodontal Health Maintenance. | Varela-Lopez A, Navarro-Hortal MD, Giampieri F, Bullon P, Battino M, Quiles JL. | Molecules | 10.3390/molecules23051226 | 2018 | | |
| Genetics | A comprehensive benchmarking study of protocols and sequencing platforms for 16S rRNA community profiling. | D'Amore R, Ijaz UZ, Schirmer M, Kenny JG, Gregory R, Darby AC, Shakya M, Podar M, Quince C, Hall N. | BMC Genomics | 10.1186/s12864-015-2194-9 | 2016 | |
| Enzymology | Lactobacilli are prominent in the initial stages of polymicrobial infection of dental pulp. | Nadkarni MA, Simonian MR, Harty DW, Zoellner H, Jacques NA, Hunter N. | J Clin Microbiol | 10.1128/jcm.01912-09 | 2010 | |
| Metabolism | Granulocyte-macrophage colony-stimulating factor amplification of interleukin-1beta and tumor necrosis factor alpha production in THP-1 human monocytic cells stimulated with lipopolysaccharide of oral microorganisms. | Baqui AA, Meiller TF, Chon JJ, Turng BF, Falkler WA. | Clin Diagn Lab Immunol | 10.1128/cdli.5.3.341-347.1998 | 1998 | |
| Genetics | Prediction of functional modules based on comparative genome analysis and Gene Ontology application. | Wu H, Su Z, Mao F, Olman V, Xu Y. | Nucleic Acids Res | 10.1093/nar/gki573 | 2005 | |
| Genetics | The genome of Erysipelothrix rhusiopathiae, the causative agent of swine erysipelas, reveals new insights into the evolution of firmicutes and the organism's intracellular adaptations. | Ogawa Y, Ooka T, Shi F, Ogura Y, Nakayama K, Hayashi T, Shimoji Y. | J Bacteriol | 10.1128/jb.01500-10 | 2011 | |
| In vitro enrofloxacin binding in human fecal slurries. | Ahn Y, Linder SW, Veach BT, Steve Yan S, Haydee Fernandez A, Pineiro SA, Cerniglia CE. | Regul Toxicol Pharmacol | 10.1016/j.yrtph.2011.11.013 | 2012 | | |
| Pathogenicity | A lactotransferrin single nucleotide polymorphism demonstrates biological activity that can reduce susceptibility to caries. | Fine DH, Toruner GA, Velliyagounder K, Sampathkumar V, Godboley D, Furgang D. | Infect Immun | 10.1128/iai.01063-12 | 2013 | |
| Genetics | Lateral transfer of genes and gene fragments in prokaryotes. | Chan CX, Beiko RG, Darling AE, Ragan MA. | Genome Biol Evol | 10.1093/gbe/evp044 | 2009 | |
| Metabolism | Treponema denticola does not induce production of common innate immune mediators from primary gingival epithelial cells. | Brissette CA, Pham TT, Coats SR, Darveau RP, Lukehart SA. | Oral Microbiol Immunol | 10.1111/j.1399-302x.2008.00452.x | 2008 | |
| Evaluation of the AnaeroPack system for growth of anaerobic bacteria. | Van Horn KG, Warren K, Baccaglini EJ. | J Clin Microbiol | 10.1128/jcm.35.8.2170-2173.1997 | 1997 | | |
| Metabolism | Short chain fatty acids potently induce latent HIV-1 in T-cells by activating P-TEFb and multiple histone modifications. | Das B, Dobrowolski C, Shahir AM, Feng Z, Yu X, Sha J, Bissada NF, Weinberg A, Karn J, Ye F. | Virology | 10.1016/j.virol.2014.10.033 | 2015 | |
| A database of bacterial lipoproteins (DOLOP) with functional assignments to predicted lipoproteins. | Babu MM, Priya ML, Selvan AT, Madera M, Gough J, Aravind L, Sankaran K. | J Bacteriol | 10.1128/jb.188.8.2761-2773.2006 | 2006 | | |
| Evaluation of the AnaeroPack system for growth of clinically significant anaerobes. | Delaney ML, Onderdonk AB. | J Clin Microbiol | 10.1128/jcm.35.3.558-562.1997 | 1997 | | |
| Enzymology | Characterization, distribution, and expression of novel genes among eight clinical isolates of Streptococcus pneumoniae. | Shen K, Gladitz J, Antalis P, Dice B, Janto B, Keefe R, Hayes J, Ahmed A, Dopico R, Ehrlich N, Jocz J, Kropp L, Yu S, Nistico L, Greenberg DP, Barbadora K, Preston RA, Post JC, Ehrlich GD, Hu FZ. | Infect Immun | 10.1128/iai.74.1.321-330.2006 | 2006 | |
| Gamma interferon (IFN-gamma) and IFN-gamma-inducing cytokines interleukin-12 (IL-12) and IL-18 do not augment infection-stimulated bone resorption in vivo. | Sasaki H, Balto K, Kawashima N, Eastcott J, Hoshino K, Akira S, Stashenko P. | Clin Diagn Lab Immunol | 10.1128/cdli.11.1.106-110.2004 | 2004 | | |
| Altered intestinal microbiota-host mitochondria crosstalk in new onset Crohn's disease. | Mottawea W, Chiang CK, Muhlbauer M, Starr AE, Butcher J, Abujamel T, Deeke SA, Brandel A, Zhou H, Shokralla S, Hajibabaei M, Singleton R, Benchimol EI, Jobin C, Mack DR, Figeys D, Stintzi A. | Nat Commun | 10.1038/ncomms13419 | 2016 | | |
| Evidence for a hybrid genomic island in verocytotoxin-producing Escherichia coli CL3 (serotype O113:H21) containing segments of EDL933 (serotype O157:H7) O islands 122 and 48. | Shen S, Mascarenhas M, Rahn K, Kaper JB, Karmali MA. | Infect Immun | 10.1128/iai.72.3.1496-1503.2004 | 2004 | | |
| Metabolism | Expression of the peptide antibiotic human beta-defensin 1 in cultured gingival epithelial cells and gingival tissue. | Krisanaprakornkit S, Weinberg A, Perez CN, Dale BA. | Infect Immun | 10.1128/iai.66.9.4222-4228.1998 | 1998 | |
| Pathogenicity | In vitro model of colonization resistance by the enteric microbiota: effects of antimicrobial agents used in food-producing animals. | Wagner RD, Johnson SJ, Cerniglia CE. | Antimicrob Agents Chemother | 10.1128/aac.00852-07 | 2008 | |
| Genetics | Modal codon usage: assessing the typical codon usage of a genome. | Davis JJ, Olsen GJ. | Mol Biol Evol | 10.1093/molbev/msp281 | 2010 | |
| Metabolism | Evolutionary primacy of sodium bioenergetics. | Mulkidjanian AY, Galperin MY, Makarova KS, Wolf YI, Koonin EV. | Biol Direct | 10.1186/1745-6150-3-13 | 2008 | |
| Annotation of Protein Domains Reveals Remarkable Conservation in the Functional Make up of Proteomes Across Superkingdoms. | Nasir A, Naeem A, Khan MJ, Nicora HD, Caetano-Anolles G. | Genes (Basel) | 10.3390/genes2040869 | 2011 | | |
| Enzymology | Antimicrobial Polymers in the Nano-World. | Alvarez-Paino M, Munoz-Bonilla A, Fernandez-Garcia M. | Nanomaterials (Basel) | 10.3390/nano7020048 | 2017 | |
| Comparison of four commercial brucella agar media for growth of anaerobic organisms. | Mangels JI, Douglas BP. | J Clin Microbiol | 10.1128/jcm.27.10.2268-2271.1989 | 1989 | | |
| Enzymology | Quantitative microbiological study of human carious dentine by culture and real-time PCR: association of anaerobes with histopathological changes in chronic pulpitis. | Martin FE, Nadkarni MA, Jacques NA, Hunter N. | J Clin Microbiol | 10.1128/jcm.40.5.1698-1704.2002 | 2002 | |
| Enzymology | Bacteriological study of periodontal lesions in two sisters with juvenile periodontitis and their mother. | Okuda K, Naito Y, Ohta K, Fukumoto Y, Kimura Y, Ishikawa I, Kinoshita S, Takazoe I. | Infect Immun | 10.1128/iai.45.1.118-121.1984 | 1984 | |
| Genetics | Minimum contradiction matrices in whole genome phylogenies. | Thuillard M. | Evol Bioinform Online | 10.4137/ebo.s909 | 2008 | |
| Enzymology | PCR detection and quantitation of predominant anaerobic bacteria in human and animal fecal samples. | Wang RF, Cao WW, Cerniglia CE. | Appl Environ Microbiol | 10.1128/aem.62.4.1242-1247.1996 | 1996 | |
| Enzymology | Detection of Porphyromonas gingivalis from saliva by PCR by using a simple sample-processing method. | Matto J, Saarela M, Alaluusua S, Oja V, Jousimies-Somer H, Asikainen S. | J Clin Microbiol | 10.1128/jcm.36.1.157-160.1998 | 1998 | |
| Intestinal microbiota as modulators of the immune system and neuroimmune system: impact on the host health and homeostasis. | Maranduba CM, De Castro SB, de Souza GT, Rossato C, da Guia FC, Valente MA, Rettore JV, Maranduba CP, de Souza CM, do Carmo AM, Macedo GC, Silva Fde S. | J Immunol Res | 10.1155/2015/931574 | 2015 | | |
| Metabolism | Ability of bacteria associated with chronic inflammatory disease to stimulate E-selectin expression and promote neutrophil adhesion. | Darveau RP, Cunningham MD, Bailey T, Seachord C, Ratcliffe K, Bainbridge B, Dietsch M, Page RC, Aruffo A. | Infect Immun | 10.1128/iai.63.4.1311-1317.1995 | 1995 | |
| Metabolism | Inhibition of microsomal prostaglandin E synthase-1 by aminothiazoles decreases prostaglandin E2 synthesis in vitro and ameliorates experimental periodontitis in vivo. | Kats A, Bage T, Georgsson P, Jonsson J, Quezada HC, Gustafsson A, Jansson L, Lindberg C, Nasstrom K, Yucel-Lindberg T. | FASEB J | 10.1096/fj.12-214445 | 2013 | |
| Metabolism | Development and characterization of a highly specific and sensitive SYBR green reverse transcriptase PCR assay for detection of the 2009 pandemic H1N1 influenza virus on the basis of sequence signatures. | Medina RA, Rojas M, Tuin A, Huff S, Ferres M, Martinez-Valdebenito C, Godoy P, Garcia-Sastre A, Fofanov Y, SantaLucia J. | J Clin Microbiol | 10.1128/jcm.01142-10 | 2011 | |
| Genetics | Coverage of whole proteome by structural genomics observed through protein homology modeling database. | Yura K, Yamaguchi A, Go M. | J Struct Funct Genomics | 10.1007/s10969-006-9010-3 | 2006 | |
| The sequence of the single 16S rRNA gene of the thermophilic eubacterium Rhodothermus marinus reveals a distant relationship to the group containing Flexibacter, Bacteroides, and Cytophaga species. | Andresson OS, Fridjonsson OH. | J Bacteriol | 10.1128/jb.176.20.6165-6169.1994 | 1994 | | |
| Transcriptional regulatory network discovery via multiple method integration: application to e. coli K12. | Sun J, Tuncay K, Haidar AA, Ensman L, Stanley F, Trelinski M, Ortoleva P. | Algorithms Mol Biol | 10.1186/1748-7188-2-2 | 2007 | | |
| Metabolism | A genomic timescale of prokaryote evolution: insights into the origin of methanogenesis, phototrophy, and the colonization of land. | Battistuzzi FU, Feijao A, Hedges SB. | BMC Evol Biol | 10.1186/1471-2148-4-44 | 2004 | |
| Detection of bacterial growth by gas absorption. | Waters JR. | J Clin Microbiol | 10.1128/jcm.30.5.1205-1209.1992 | 1992 | | |
| Identification of SmtB/ArsR cis elements and proteins in archaea using the Prokaryotic InterGenic Exploration Database (PIGED). | Bose M, Slick D, Sarto MJ, Murphy P, Roberts D, Roberts J, Barber RD. | Archaea | 10.1155/2006/837139 | 2006 | | |
| The use of monoclonal antibodies to detect Bacteroides gingivalis in biological samples. | Chen P, Bochacki V, Reynolds HS, Beanan J, Tatakis DN, Zambon JJ, Genco RJ. | Infect Immun | 10.1128/iai.54.3.798-803.1986 | 1986 | | |
| Metabolism | A guild of 45 CRISPR-associated (Cas) protein families and multiple CRISPR/Cas subtypes exist in prokaryotic genomes. | Haft DH, Selengut J, Mongodin EF, Nelson KE. | PLoS Comput Biol | 10.1371/journal.pcbi.0010060 | 2005 | |
| Diversity in domain architectures of Ser/Thr kinases and their homologues in prokaryotes. | Krupa A, Srinivasan N. | BMC Genomics | 10.1186/1471-2164-6-129 | 2005 | | |
| Phylogeny | Proteome-wide functional classification and identification of prokaryotic transmembrane proteins by transmembrane topology similarity comparison. | Arai M, Okumura K, Satake M, Shimizu T. | Protein Sci | 10.1110/ps.04814404 | 2004 | |
| Compilation of small ribosomal subunit RNA structures. | Neefs JM, Van de Peer Y, De Rijk P, Chapelle S, De Wachter R. | Nucleic Acids Res | 10.1093/nar/21.13.3025 | 1993 | | |
| Enzymology | Purification and characterization of allophanate hydrolase (AtzF) from Pseudomonas sp. strain ADP. | Shapir N, Sadowsky MJ, Wackett LP. | J Bacteriol | 10.1128/jb.187.11.3731-3738.2005 | 2005 | |
| Enzymology | Comparison of randomly cloned and whole genomic DNA probes for the detection of Porphyromonas gingivalis and Bacteroides forsythus. | Wong M, DiRienzo JM, Lai CH, Listgarten MA. | J Periodontal Res | 10.1111/j.1600-0765.1996.tb00460.x | 1996 | |
| Composition of peptidoglycans in Bacteroidaceae: determination and distribution of lanthionine. | Vasstrand EN, Jensen HB, Miron T, Hofstad T. | Infect Immun | 10.1128/iai.36.1.114-122.1982 | 1982 | | |
| Enzymology | Extraction, purification, and characterization of major outer membrane proteins from Wolinella recta ATCC 33238. | Kennell WL, Holt SC. | Infect Immun | 10.1128/iai.59.10.3740-3749.1991 | 1991 | |
| Metabolism | Reconstructing the mosaic glycolytic pathway of the anaerobic eukaryote Monocercomonoides. | Liapounova NA, Hampl V, Gordon PM, Sensen CW, Gedamu L, Dacks JB. | Eukaryot Cell | 10.1128/ec.00258-06 | 2006 | |
| Metabolism | Absence of alphavbeta6 integrin is linked to initiation and progression of periodontal disease. | Ghannad F, Nica D, Fulle MI, Grenier D, Putnins EE, Johnston S, Eslami A, Koivisto L, Jiang G, McKee MD, Hakkinen L, Larjava H. | Am J Pathol | 10.2353/ajpath.2008.071068 | 2008 | |
| Enzymology | Use of synthetic oligonucleotide DNA probes for identification and direct detection of Bacteroides forsythus in plaque samples. | Moncla BJ, Motley ST, Braham P, Ewing L, Adams TH, Vermeulen NM. | J Clin Microbiol | 10.1128/jcm.29.10.2158-2162.1991 | 1991 | |
| Biotechnology | Detection of Salmonella spp. in oysters by PCR. | Bej AK, Mahbubani MH, Boyce MJ, Atlas RM. | Appl Environ Microbiol | 10.1128/aem.60.1.368-373.1994 | 1994 | |
| Enzymology | Detection of Mycobacterium tuberculosis by PCR amplification with pan-Mycobacterium primers and hybridization to an M. tuberculosis-specific probe. | Tevere VJ, Hewitt PL, Dare A, Hocknell P, Keen A, Spadoro JP, Young KK. | J Clin Microbiol | 10.1128/jcm.34.4.918-923.1996 | 1996 | |
| Phylogeny | Micromethod system for identification of anaerobic bacteria. | Starr SE, Thompson FS, Dowell VR, Balows A. | Appl Microbiol | 10.1128/am.25.5.713-717.1973 | 1973 | |
| Xenobiotic efflux in bacteria and fungi: a genomics update. | Barabote RD, Thekkiniath J, Strauss RE, Vediyappan G, Fralick JA, San Francisco MJ. | Adv Enzymol Relat Areas Mol Biol | 10.1002/9780470920541.ch6 | 2011 | | |
| Enzymology | Development of a differential medium for bile salt hydrolase-active Lactobacillus spp. | Dashkevicz MP, Feighner SD. | Appl Environ Microbiol | 10.1128/aem.55.1.11-16.1989 | 1989 | |
| Enzymology | Evaluation of an immunofluorescent-antibody test for rapid identification of Pseudomonas aeruginosa in blood cultures. | Counts GW, Schwartz RW, Ulness BK, Hamilton DJ, Rosok MJ, Cunningham MD, Tam MR, Darveau RP. | J Clin Microbiol | 10.1128/jcm.26.6.1161-1165.1988 | 1988 | |
| Enzymology | Identification of Bacteroides forsythus in subgingival plaque from patients with advanced periodontitis. | Gersdorf H, Meissner A, Pelz K, Krekeler G, Gobel UB. | J Clin Microbiol | 10.1128/jcm.31.4.941-946.1993 | 1993 | |
| Phylogeny | Systematic analysis of compositional order of proteins reveals new characteristics of biological functions and a universal correlate of macroevolution. | Persi E, Horn D. | PLoS Comput Biol | 10.1371/journal.pcbi.1003346 | 2013 | |
| Pathogenicity | In vitro susceptibilities of suspected periodontopathic anaerobes as determined by membrane transfer assay. | Caufield PW, Allen DN, Childers NK. | Antimicrob Agents Chemother | 10.1128/aac.31.12.1989 | 1987 | |
| Enzymology | 6-phospho-alpha-D-glucosidase from Fusobacterium mortiferum: cloning, expression, and assignment to family 4 of the glycosylhydrolases. | Bouma CL, Reizer J, Reizer A, Robrish SA, Thompson J. | J Bacteriol | 10.1128/jb.179.13.4129-4137.1997 | 1997 | |
| Cultivation | Comparison of media in the Anaerobe-Tek and Presumpto plate systems and evaluation of the Anaerobe-Tek system for identification of commonly encountered anaerobes. | Lombard GL, Whaley DN, Dowell VR. | J Clin Microbiol | 10.1128/jcm.16.6.1066-1072.1982 | 1982 | |
| Genetics | Fine-structured multi-scaling long-range correlations in completely sequenced genomes--features, origin, and classification. | Knoch TA, Goker M, Lohner R, Abuseiris A, Grosveld FG. | Eur Biophys J | 10.1007/s00249-009-0489-y | 2009 | |
| The TetR family of transcriptional repressors. | Ramos JL, Martinez-Bueno M, Molina-Henares AJ, Teran W, Watanabe K, Zhang X, Gallegos MT, Brennan R, Tobes R. | Microbiol Mol Biol Rev | 10.1128/mmbr.69.2.326-356.2005 | 2005 | | |
| Phylogeny | DNA probes for identification of clinically important Bacteroides species. | Kuritza AP, Getty CE, Shaughnessy P, Hesse R, Salyers AA. | J Clin Microbiol | 10.1128/jcm.23.2.343-349.1986 | 1986 | |
| Phylogeny | New medium for selection and presumptive identification of the Bacteroides fragilis group. | Livingston SJ, Kominos SD, Yee RB. | J Clin Microbiol | 10.1128/jcm.7.5.448-453.1978 | 1978 | |
| Lymphoproliferative responses to oral bacteria in humans with varying severities of periodontal disease. | Patters MR, Chen P, McKenna J, Genco RJ. | Infect Immun | 10.1128/iai.28.3.777-784.1980 | 1980 | | |
| Metabolism | Rickettsia phylogenomics: unwinding the intricacies of obligate intracellular life. | Gillespie JJ, Williams K, Shukla M, Snyder EE, Nordberg EK, Ceraul SM, Dharmanolla C, Rainey D, Soneja J, Shallom JM, Vishnubhat ND, Wattam R, Purkayastha A, Czar M, Crasta O, Setubal JC, Azad AF, Sobral BS. | PLoS One | 10.1371/journal.pone.0002018 | 2008 | |
| Enzymology | Identification and characterization of the major cell envelope proteins of oral strains of Actinobacillus actinomycetemcomitans. | Di Rienzo JM, Spieler EL. | Infect Immun | 10.1128/iai.39.1.253-261.1983 | 1983 | |
| Genetics | Genomics of bacteria and archaea: the emerging dynamic view of the prokaryotic world. | Koonin EV, Wolf YI. | Nucleic Acids Res | 10.1093/nar/gkn668 | 2008 | |
| Metabolism | How phosphotransferase system-related protein phosphorylation regulates carbohydrate metabolism in bacteria. | Deutscher J, Francke C, Postma PW. | Microbiol Mol Biol Rev | 10.1128/mmbr.00024-06 | 2006 | |
| Evaluation of Periodontitis and Fusobacterium nucleatum Among Colorectal Cancer Patients: An Observational Cross-Sectional Study. | Antonacci A, Bizzoca C, Barile G, Andriola V, Vincenti L, Bartolomeo N, Abbinante A, Orru G, Corsalini M. | Healthcare (Basel) | 10.3390/healthcare12212189 | 2024 | | |
| Extracellular vesicles from Aggregatibacter actinomycetemcomitans exhibit potential antitumorigenic effects in oral cancer: a comparative in vitro study. | Metsaniitty M, Hasnat S, Ohman C, Salo T, Eklund KK, Oscarsson J, Salem A. | Arch Microbiol | 10.1007/s00203-024-03976-8 | 2024 | | |
| Changes in the oral status and periodontal pathogens in a Sardinian rural community from pre-industrial to modern time. | Casula E, Contu MP, Demontis C, Coghe F, Steri GC, Scano A, Ferrando ML, Orru G. | Sci Rep | 10.1038/s41598-022-20193-9 | 2022 | | |
| Enzymology | Optimization of quantitative polymerase chain reactions for detection and quantification of eight periodontal bacterial pathogens. | Decat E, Cosyn J, De Bruyn H, Miremadi R, Saerens B, Van Mechelen E, Vermeulen S, Vaneechoutte M, Deschaght P. | BMC Res Notes | 10.1186/1756-0500-5-664 | 2012 | |
| Agarooligosaccharides as a novel concept in prebiotics: selective inhibition of Ruminococcus gnavus and Fusobacterium nucleatum while preserving Bifidobacteria, Lactobacillales in vitro, and inhibiting Lachnospiraceae in vivo. | Fujii T, Karasawa K, Takahashi H, Shirai I, Funasaka K, Ohno E, Hirooka Y, Tochio T. | Microbiology (Reading) | 10.1099/mic.0.001510 | 2024 | | |
| Clostridium butyricum-altered lung microbiome is associated with enhanced anti-influenza effects via G-protein-coupled receptor120. | Hagihara M, Yamashita M, Ariyoshi T, Minemura A, Yoshida C, Higashi S, Oka K, Takahashi M, Ota A, Maenaka A, Iwasaki K, Hirai J, Shibata Y, Umemura T, Mori T, Kato H, Asai N, Mikamo H. | iScience | 10.1016/j.isci.2025.113502 | 2025 | | |
| Development of Chimera AMP-Endolysin with Wider Spectra Against Gram-Negative Bacteria Using High-Throughput Assay. | Kogawa M, Yoda T, Matsuhashi A, Matsushita A, Otsuka Y, Shibagaki S, Hosokawa M, Tsuda S. | Viruses | 10.3390/v17020200 | 2025 | | |
| Pathogenicity | Growth stimulation of Bifidobacterium from human colon using daikenchuto in an in vitro model of human intestinal microbiota. | Sasaki K, Sasaki D, Sasaki K, Nishidono Y, Yamamori A, Tanaka K, Kondo A. | Sci Rep | 10.1038/s41598-021-84167-z | 2021 | |
| Metabolism | Gut bacteria identified in colorectal cancer patients promote tumourigenesis via butyrate secretion. | Okumura S, Konishi Y, Narukawa M, Sugiura Y, Yoshimoto S, Arai Y, Sato S, Yoshida Y, Tsuji S, Uemura K, Wakita M, Matsudaira T, Matsumoto T, Kawamoto S, Takahashi A, Itatani Y, Miki H, Takamatsu M, Obama K, Takeuchi K, Suematsu M, Ohtani N, Fukunaga Y, Ueno M, Sakai Y, Nagayama S, Hara E. | Nat Commun | 10.1038/s41467-021-25965-x | 2021 | |
| Bacterial syntenies: an exact approach with gene quorum. | Denielou YP, Sagot MF, Boyer F, Viari A. | BMC Bioinformatics | 10.1186/1471-2105-12-193 | 2011 | | |
| Microbial oncogenesis: the impact of Fusobacterium nucleatum on oral cancer pathways. | Srivastava S, Kumar S. | Med Oncol | 10.1007/s12032-025-03150-0 | 2025 | | |
| Fusobacterium nucleatum Increases Growth of Motile Bacterium Treponema denticola without Contact In Vitro. | Kikuchi Y, Kokubu E, Ishihara K. | Bull Tokyo Dent Coll | 10.2209/tdcpublication.2025-0015 | 2025 | | |
| Fusobacterium nucleatum-reprogrammed adipocytes promote tumor cisplatin resistance through the CCL2-CCR2 axis in the necrotic metastatic neck nodes of head and neck carcinoma. | Li F, Yuan X, Lau HC, Zhu Y, Gong H, Huang H, Hsueh CY, Zhang M. | Cell Commun Signal | 10.1186/s12964-025-02550-z | 2025 | | |
| Understanding the potential of probiotics in oral cancer prevention: a short review on microbial modulation. | Rivera C. | Discov Oncol | 10.1007/s12672-025-04020-x | 2025 | | |
| Fusobacterium nucleatum-targeted polymeric micelles disrupting biofilm-immune crosstalk for precision colorectal cancer immunotherapy. | Wu T, Zhang F, Liu H, Ma F, Yu Y, Sun D, Ren J, Wang W, Elsabahy M, Gao H. | J Control Release | 10.1016/j.jconrel.2025.114400 | 2025 | | |
| Eliminating intratumoral bacteria with cGAS-STING-activating nanodrug-bacteria biohybrids potentiates cancer immunotherapy | Zhou X, Pan X, Shen Z, Kang R, Pang Y, Luo L, Liu F, Yu S, Zhang J, Shen Q. | Biomaterials. | 2026 | | ||
| Periodontitis, Fusobacterium nucleatum, and Colorectal Carcinoma. A Review. | Straka M, Borecova P, Straka M. | Neuro Endocrinol Lett | 2025 | | ||
| Sorafenib and ponatinib as effective inhibitors of Fusobacterium nucleatum FtsZ: An in silico and in vitro study. | Fang H, Jin Y, Yang M, Li Y, Shu Y, Si Z, Cheng Z, Zhao F, Zhu H, Liu Y, Chen P. | Int J Biol Macromol | 10.1016/j.ijbiomac.2025.148363 | 2025 | | |
| Development of an Aptamer/CRISPR-Cas12a-Based Dual-Modal Biosensor for Fusobacterium nucleatum Detection in Non-Invasive Colorectal Cancer Screening. | Wang X, Feng S, Chen H, Zhou B, Fan T, Qin Y, Zhao L, Jiang Y, Chen Y. | Anal Chem | 10.1021/acs.analchem.5c04132 | 2025 | | |
| Combination effects of Nd:YAP laser and DNase I on dual-species biofilm removal in a simulated lateral canal model: An in vitro study. | Ye J, Wen T, Liu Q, Ma B, Yang Y, Wang Y, Yu S, Yan J, Zhang J, Liu Y. | Eur J Oral Sci | 10.1111/eos.70051 | 2025 | | |
| Dual Targeting Biomimetic Nanoplatform Eradicates Oncogenic Bacteria While Reinvigorating Anti-Tumor Immunity in Breast Cancer. | Yang L, Zhang Y, Chen T, Han J, Wang H, Zhang M, Bao Q, Diao Z, Zhang T, Jiang Y, Huang S, Zhang L. | ACS Appl Mater Interfaces | 10.1021/acsami.5c16642 | 2025 | | |
| Pathogenicity | The Role of Non-Helicobacter Pylori Bacteria in the Pathogenesis of Gastric Diseases. | Tiwari R, Tiwari G, Gupta A, Ramachandran V. | Zhongguo Ying Yong Sheng Li Xue Za Zhi | 10.62958/j.cjap.2025.027 | 2025 | |
| Genetics | Porphyromonas gingivalis and Fusobacterium nucleatum synergistically strengthen the effect of promoting oral squamous cell carcinoma progression. | Song X, Wang J, Gu Z, Qiu X, Yuan M, Ke H, Deng R. | Infect Agent Cancer | 10.1186/s13027-025-00689-5 | 2025 | |
| Antimicrobial and antibiofilm effects of a leucine-substituted rice peptide against Porphyromonas gingivalis and Fusobacterium nucleatum. | Aoki-Nonaka Y, Matsugishi-Nasu A, Lwin HY, Minato Y, Ando D, Warita Y, Takahashi N, Tabeta K. | Microb Pathog | 10.1016/j.micpath.2025.108052 | 2025 | | |
| Intratumoral microbiome in breast cancer: A hidden player in tumor development, progression and treatment response. | Canzian J, Jacobs F, Floreani A, Miggiano C, Tiberio P, Pozzi C, Santoro A, Zambelli A, Rescigno M, De Sanctis R. | Crit Rev Oncol Hematol | 10.1016/j.critrevonc.2025.105035 | 2025 | | |
| Fusobacterium nucleatum: ecology, pathogenesis and clinical implications. | Jiang SS, Chen YX, Fang JY. | Nat Rev Microbiol | 10.1038/s41579-025-01237-z | 2025 | | |
| Structural basis of Fusobacterium nucleatum adhesin Fap2 interaction with receptors on cancer and immune cells. | Schopf F, Marongiu GL, Milaj K, Sprink T, Kikhney J, Moter A, Roderer D. | Nat Commun | 10.1038/s41467-025-63451-w | 2025 | | |
| Mediated electron transfer in five prevalent human oral microbial species. | Hernandez-Villamor D, Jeaidi A, Boydens R, Rabaey K, Van de Wiele T, Prevoteau A. | Bioelectrochemistry | 10.1016/j.bioelechem.2025.109149 | 2025 | | |
| Prognostic impact of Fusobacterium nucleatum on survival in colorectal cancer: A systematic review and meta-analysis. | Wang T, Lin S, Ji Y, Puqiong C, Gao J, Li S. | J Cancer Res Ther | 10.4103/jcrt.jcrt_38_24 | 2025 | | |
| Fusobacterium nucleatum and Gastric Cancer: An Emerging Connection. | Sorino J, Della Mura M, Ingravallo G, Cazzato G, Pizzimenti C, Zuccala V, Pepe L, Germana E, Martini M, Ieni A, Fiorentino V. | Int J Mol Sci | 10.3390/ijms26167915 | 2025 | | |
| Fusobacterium nucleatum enhances amphetamine-induced behavioral responses through a butyrate-driven epigenetic mechanism. | Mabry SJ, Cao X, Zhu Y, Rowe C, Patel S, Gonzalez-Arancibia C, Romanazzi T, Saleeby DP, Elam A, Lee HT, Turkmen S, Lauzon SN, Hernandez CE, Sun H, Wu H, Carter AM, Galli A. | Sci Signal | 10.1126/scisignal.adx7729 | 2025 | | |
| Co-Infection by Porphyromonas gingivalis and Fusobacterium nucleatum Increases PD-L1 Expression in Esophageal Cancer Tissues. | Lin X, Chen X, Chen M, Li Y, Deng Y, Xian B, Li Z. | Microbiologyopen | 10.1002/mbo3.70050 | 2025 | | |
| Proteome | Characterization of the OMP biogenesis machinery in Fusobacterium nucleatum. | Cottom CO, Heinz E, Erramilli S, Kossiakoff A, Slade DJ, Noinaj N. | Structure | 10.1016/j.str.2025.08.008 | 2025 | |
| Binding of Fusobacterium nucleatum autotransporter adhesin CbpF to human CEACAM1 and CEACAM5: A Velcro model for bacterium adhesion. | Shen F, Li L, Yang D, Tang Z, Zhang L, Liu K, Hou W, Lu Z, Fang JY, Qi J, Zhao X, Gao GF. | Proc Natl Acad Sci U S A | 10.1073/pnas.2516574122 | 2025 | | |
| Fusobacterium nucleatum Infection Drives Glutathione Depletion in Gastric Cancer: Integrated Multi-Omics and Experimental Validation. | Nie S, Gong Y, Wang A, Guo R, Chen X, Yuan Y. | Microorganisms | 10.3390/microorganisms13081907 | 2025 | | |
| The interactions of Fusobacterium nucleatum and Porphyromonas gingivalis with microRNAs: contributions to oral squamous cell carcinoma. | Khoshbayan A, Narimisa N, Razavi S, Shariati A, Tavakoli-Yaraki M, Darban-Sarokhalil D, Emami Razavi A. | Mol Biol Rep | 10.1007/s11033-025-10926-0 | 2025 | | |
| Fusobacterium nucleatum promotes bladder cancer progression and immune escape by activating the IL22/STAT3/PD-L1 signaling cascade. | Yang Y, Chen Y, Liu Q, Guan L, Liang G. | Tissue Cell | 10.1016/j.tice.2025.103065 | 2025 | | |
| The oral microbiota change in oral cancer - a preliminary study. | Swiatkowski W, Bakiera A, Rahnama-Hezavah M, Grywalska E, Niedzielski A, Korona-Glowniak I. | Ann Agric Environ Med | 10.26444/aaem/209080 | 2025 | | |
| Engineered tumor-symbiotic bacterial membrane nanovesicles enable precise immuno-chemotherapy of colorectal cancer. | Lu S, Miao Y, Wang D, Xu D, Liu R, Liu X, Zhang Y, Zhang X, Qin H. | J Control Release | 10.1016/j.jconrel.2025.114291 | 2025 | | |
| The in vitro antibacterial efficacy of advanced platelet-rich fibrin plus supplemented with metronidazole against Fusobacterium nucleatum. | Huynh-Pham AT, Le SH, Nguyen BT. | Clin Oral Investig | 10.1007/s00784-025-06431-0 | 2025 | | |
| Role of Fusobacterium nucleatum in the pathogenesis of oral squamous cell carcinoma: A systematic review of molecular mechanisms and signalling pathways. | El-Dwaikat B, El Karim I, Longley DB, Moynagh PN, Lundy FT. | Arch Oral Biol | 10.1016/j.archoralbio.2025.106369 | 2025 | | |
| Research progress on gut microbiota in colorectal cancer immunotherapy. | Li J, Yue Y, Pan J, Liang F. | Biochim Biophys Acta Rev Cancer | 10.1016/j.bbcan.2025.189476 | 2025 | | |
| Pathogenicity | Technology-Enabled Integration of Single-Cell Transcriptomics and Microbiome Data Identifies RNA-Targetable Host-Microbiota Networks in Colorectal Adenoma. | Ma B, Hu H, Lin Y, Wang Z, Song Q. | SLAS Technol | 10.1016/j.slast.2025.100365 | 2025 | |
| Immune responses of multi-epitope recombinant vaccine candidate strains against Fusobacterium nucleatum in mice. | Xu HW, Li P, Zhu SL. | Microb Pathog | 10.1016/j.micpath.2025.107824 | 2025 | | |
| Pathogenicity | Gut commensal microbiota drive tailored macrophage responses. | Jones J, Garcia-Martinez KY, Lee YY, Rhee M, Nath RR, Takahashi S, Grodner B, De Vlaminck I, Leifer CA, Brito IL. | Cell Rep | 10.1016/j.celrep.2025.116157 | 2025 | |
| Enzymology | Direct iron-protein coordination is dispensable for heme trafficking and the tetrapyrrole reductase activity of HmuF from Fusobacterium nucleatum. | McGregor AK, Do LTM, Gauvin A, Wolthers KR. | Arch Biochem Biophys | 10.1016/j.abb.2025.110520 | 2025 | |
| Efficacy of Photodynamic Therapy in Controlling Gingival Inflammation in Orthodontic Patients: A Network Meta-Analysis. | Vieira RA, Martins-Pfeifer C, Carvalho FG, Munchow EA, Campos MJDS, Lacerda-Santos R. | Eur J Dent | 10.1055/s-0045-1812493 | 2025 | | |
| SmartGel OV: A Natural Origanum vulgare-Based Adjunct for Periodontitis with Clinical and Microbiological Evaluation. | Radu CM, Radu CC, Zaha DC. | Medicina (Kaunas) | 10.3390/medicina61081423 | 2025 | | |
| Inhibitory potential of probiotic strains against pathogens associated with osteomyelitis of the jaws: a quantitative MIC and MBC analysis. | Baazeem M, Niazy A, Rabea S, Alomiery AA. | Cell Mol Biol (Noisy-le-grand) | 10.14715/cmb/2025.71.6.9 | 2025 | | |
| Effectiveness of Botanical Oral Health Products in Reducing Pathogenic Bacterial Overgrowth and Improving Gingival Health: A Case Report. | Ebrahimian A, Manske S, D'Adamo CR, Klos-Maki K. | Altern Ther Health Med | 2025 | | ||
| Rare intra-tumoral colonization of Fusobacterium nucleatum in endometrial cancer. | Dos Reis MB, Basso DAA, Bonatelli M, Berardinelli GN, Teixeira GR, Reis RD, Reis RM. | Int J Gynecol Cancer | 10.1016/j.ijgc.2025.101979 | 2025 | | |
| Gut microbiota and chemoradiotherapy response in rectal cancer: Biomarker opportunities. | Taoum C, Devaux A, Rouanet P, Colombo PE, Boucher D, Bonnet M. | Crit Rev Oncol Hematol | 10.1016/j.critrevonc.2025.104974 | 2025 | | |
| Guanxinning attenuates diabetic myocardial ischemia-reperfusion injury by targeting oral Fusobacterium nucleatum and modulating PTEN signaling. | Li Y, Xu Q, Liu Y, Liu L, Wang W, Zhu M, Cui J, Yang H, Liu Y. | Front Pharmacol | 10.3389/fphar.2025.1581413 | 2025 | | |
| Gut microbiota-mediated oncogenesis in hepatocellular carcinoma: a new avenue for therapeutic intervention. | Ramesh A, Subbarayan R, Srinivasan D, Balakrishnan R, Shrestha R, Chauhan A. | Int J Surg | 10.1097/js9.0000000000003851 | 2025 | | |
| Pathogenicity | Investigating the Impact of Fusobacterium nucleatum on Oxidative Stress, Chemoresistance, and Inflammation in Inflammatory Bowel Disease and Colorectal Cancer: Rationale and Design of a Clinical Trial. | Consolo P, Giorgi C, Crisafulli C, Fiorica F, Pinton P, Maurea N, Missiroli S, Quagliariello V, Mantoan B, Ottaiano A, Pellicano GF, Orru G, Scano A, Cacciola I, Pollicino T, Di Mauro G, Berretta S, Bignucolo A, Toscano E, Ciappina G, Berretta M. | Int J Mol Sci | 10.3390/ijms26167823 | 2025 | |
| Orally Deliverable Engineered Porphyrin Nanohybrids Activate the cGAS-STING Axis and Enable Fusobacterium-Specific Targeting for Robust Immune Remodeling and Colorectal Cancer Regression. | Liang R, Lin F, Mo X, Long J, Tang W, Luo T, Huang Y. | ACS Appl Mater Interfaces | 10.1021/acsami.5c09122 | 2025 | | |
| Intratumoral bacterial microbiota in gastrointestinal adenocarcinoma: From computational insights to clinical practice. | Yousefi-Hashemabad MJ, Hosseini Kakroudi M, Pourashory M, Forouzan K, Yazdanpanah N, Saleki K, Rezaei N. | Microb Pathog | 10.1016/j.micpath.2025.108174 | 2025 | | |
| Targeting Microbiome-Derived Exosomes to Overcome Cancer Therapy Resistance: Mechanisms, Implications, and Opportunities. | Singh V, Shirbhate E, Kore R, Veerasamy R, Sharma PC, Tiwari AK, Rajak H. | Mini Rev Med Chem | 10.2174/0113895575416455251014053321 | 2025 | | |
| Infectious Carcinogens Derived from Intestinal Microflora: Mechanisms of Microbial Transitions from Eubionts to Pathobionts. | Pai YC, Huang CY, Lin LY, Li YH, Yu LC. | J Physiol Investig | 10.4103/ejpi.ejpi-d-25-00045 | 2025 | | |
| Metabolic fingerprinting of periodontal bacteria: a multi-scale mass spectrometry and vibrational spectroscopy approach. | Albahri J, Smaje D, Xu Y, Robinson S, Allison H, Whitehead KA, Muhamadali H. | Analyst | 10.1039/d5an00507h | 2025 | | |
| Mediator Complex Subunit 27-Enriched Small Extracellular Vesicles Mediate the Crosstalk between Periodontal Bacteria and HPV-Driven Head and Neck Cancer. | Qin TX, Ng WH, Ng SK, Zhu YY, Chek MF, Tang KD. | J Proteome Res | 10.1021/acs.jproteome.5c00373 | 2025 | | |
| Metronidazole-Loaded Cyclodextrin Nanogels for Antibacterial Therapy and Microbiota Regulation in Periodontitis. | Ji Y, Zhang R, Xu D, van der Wel PCA, Lasorsa A, Li G, Guo F, Zhou Q, van Rijn P. | Adv Healthc Mater | 10.1002/adhm.202502965 | 2025 | | |
| Cerebrovascular Vasospasms, Cerebral Sinus Venous Thrombosis, and Rapid Empyema Reaccumulation in a Child with a Coinfection of Fusobacterium nucleatum and Prevotella loescheii. | Geiser R, Zorio O, Appavu B. | J Child Neurol | 10.1177/08830738251339048 | 2025 | | |
| Intracellular Bacteria in Stem Cells of the Apical Papilla: A "Trojan Horse" for Regenerative Endodontic Failure. | Kalimuthu S, Neelakantan P. | J Endod | 10.1016/j.joen.2025.10.007 | 2025 | | |
| Fusobacterium nucleatum downregulated MLH1 expression in colorectal cancer by activating autophagy-lysosome pathway. | Ding T, Wu M, Zhao L, Liu H, Cao X, Guo J, Zhu X, Zhao L, Zhang H, Gao Y, Wei Q. | Front Immunol | 10.3389/fimmu.2025.1586146 | 2025 | | |
| Effect of a Probiotic Combination on Clinical and Microbiological Oral Parameters in Head and Neck Cancer Patients: A Randomised Clinical Trial. | Pereira Riveros T, Jane Salas E, Lozano Borbalas A, Aguilera FR, Vinuesa Aumedes T. | Cancers (Basel) | 10.3390/cancers17152459 | 2025 | | |
| Fusobacterium nucleatum is not significantly present in eutopic endometrium from patients with minimal-mild and moderate-severe endometriosis. | Graciano-Espana MC, Barnhart K, Gonzalez-Monfort M, Arenas-Barrero M, Legro RS, Thomas TR, Rush MA, Vilella F, Fernandez-Sanchez M, Simon C, Moreno I. | Fertil Steril | 10.1016/j.fertnstert.2025.06.035 | 2025 | | |
| Highly Sensitive DNA Testing of Fusobacterium nucleatum in Colorectal Tumors. | Hullar MAJ, Kahsai OJ, Hill C, Levy L, Malen RC, Curtis KR, Ammar H, Sillah A, Reedy AM, Lampe JW, Ogino S, Potter JD, Newcomb PA, Phipps AI. | Cancer Epidemiol Biomarkers Prev | 10.1158/1055-9965.epi-24-1020 | 2025 | | |
| Papilla preservation flap surgery and endoscope-assisted subgingival debridement for Step 3 therapy: A 12-month pilot study on subgingival microbial community dynamics in deep periodontal pockets. | Ho KD, Wang M, Ho KR, Tong WM, Tonetti MS, Leung WK. | J Dent | 10.1016/j.jdent.2025.106058 | 2025 | | |
| Integrated oral-gut microbiota therapy: a novel perspective on preventing bacterial translocation for systemic disease management. | Zhu J, Jiang Z, Yu F, Gao L, Wang X, Wang Q. | Front Cell Infect Microbiol | 10.3389/fcimb.2025.1641816 | 2025 | | |
| Fusobacterium nucleatum enhances cholesterol biosynthesis in colorectal cancer via miR-130a-3p-mediated AMPK inhibition, a process counteracted by butyrate. | Sun Y, Lu J, Tung Lau EY, Zeng Y, Lam Li SW, Au TH, Ye S, Zhou T, Chan FK, Liang JQ. | Cancer Lett | 10.1016/j.canlet.2025.217810 | 2025 | | |
| Potential role of intratumoral Fusobacterium nucleatum and interleukin-1 beta in breast cancer cell growth. | Chang CM, Lam LY, Lam HYP, Kao PY, Hsu ST, Wu WJ, Chang KC, Huang CY. | J Microbiol Immunol Infect | 10.1016/j.jmii.2025.05.008 | 2025 | | |
| Fusobacterium nucleatum exacerbates colitis via STAT3 activation induced by Acetyl-CoA accumulation. | Xiang Z, Li X, Wang X, Deng B, He H, Xu M, Wu X, Tan C, Liu Y, Yu B, Zhang J, Dong W. | Gut Microbes | 10.1080/19490976.2025.2489070 | 2025 | | |
| Anti-inflammatory and antimicrobial evaluation of Ceratonia siliqua-mediated calcium hydroxide nanoparticles synthesized using a one-pot technique in vitro study. | AlDhalaan N, Devanesan S, Alghamdi OG, AlWadaan MA, Al-Badah A, Seif SA. | Microb Pathog | 10.1016/j.micpath.2025.107991 | 2025 | | |
| High-throughput competitive binding assay for targeting RNA tertiary structures with small molecules: application to pseudoknots and G-quadruplexes. | Wintermans SEL, Hoffmann JS, van Kuijk V, Durmus Y, Tacoma MD, Broekhuizen I, Janssen APA, van den Elst H, van Doodewaerd BR, Geurink PP, Artola M, Olsthoorn RCL. | Nucleic Acids Res | 10.1093/nar/gkaf819 | 2025 | | |
| Oral Microbiome and Adverse Pregnancy Outcomes. | Dodson B, Suner T, Haar ELV, Han YW. | Am J Reprod Immunol | 10.1111/aji.70107 | 2025 | | |
| Microbiome-Mediated Modulation of the Tumour Immune Microenvironment in Oesophageal Squamous Cell Carcinoma. | Bai L, Zhu A. | Adv Biol (Weinh) | 10.1002/adbi.202400823 | 2025 | | |
| Determination of Fusobacterium nucleatum levels in patients with periodontal disease and oral squamous cell carcinoma. | Shunmugavelu K, Shakthi Chakravarthy BG, Priya S. | GMS Hyg Infect Control | 10.3205/dgkh000589 | 2025 | | |
| Microbiota-driven epigenetic modifications in gastrointestinal cancer: Implications for pathogenesis and therapeutic strategies | Rahimi-kolour H, Eshaghi HS, Shams E, Sanjabi F, Nobili S, Raeisi H, Sadeghi A, Nazemalhosseini-Mojarad E, Fatemi N. | World J Microbiol Biotechnol. | 2025 | | ||
| Unraveling the Role of Gut Microbiota in Colorectal Cancer: A Global Perspectives and Biomarkers as Early Screening Tool for Colorectal Cancer. | Upadhyay U, Dhar E, Bomrah S, Syed-Abdul S. | Stud Health Technol Inform | 10.3233/shti251018 | 2025 | | |
| Targeted next-generation sequencing reveals pathogen mono- and co-detection patterns in pediatric Mycoplasma pneumoniae pneumonia. | Wu G, Zheng Y, Yuan K, Bao Y, Li L, Li Y, Wang W, Wang H. | Infect Genet Evol | 10.1016/j.meegid.2025.105832 | 2025 | | |
| Coaggregation of oral pathogens by postbiotic lactobacilli. | Golletz P, Jensen SD, Collignon M, Hall C, Khamas AB, Mollebjerg A, Schlafer S, Meyer RL, Tykwinska K. | J Oral Microbiol | 10.1080/20002297.2025.2508483 | 2025 | | |
| Analysis of factors affecting fluctuations in urinary oxygen tension and relationship to obligate anaerobic bacterial growth. | Sato Y, Ichihara K, Kobayashi R, Nirasawa S, Katayama Y, Murai R, Takahashi S. | J Infect Chemother | 10.1016/j.jiac.2025.102757 | 2025 | | |
| Development of an injectable salicylic acid-choline eutectic hydrogel for enhanced treatment of periodontitis. | Zhang J, Meng L, Jia Y, Li J, Xu X, Xu X. | Mater Horiz | 10.1039/d4mh01563k | 2025 | | |
| Mechanisms of Osteoblast-Like Cells and Bacterial Responses to Copper in Titanium-Copper Alloys. | Khalid J, Stephen AS, Rawlinson SCF, Allaker RP. | J Biomed Mater Res A | 10.1002/jbm.a.37991 | 2025 | | |
| The current report on drug development focuses on "The new dimension" of cancer hallmarks. | Ucche S, Larasati YA, Maharani D, Widyardhita MH, Widayanti WR, Hermawan A. | Gene | 10.1016/j.gene.2025.149750 | 2025 | | |
| Outer membrane vesicle-coated ferrocene nanoparticles induce dual ferroptosis for cancer immunotherapy. | Shen Z, Pang Y, Kang R, Zhou X, Li C, Yu S, Luo L, Liu F, Zhang J, Shen Q. | J Control Release | 10.1016/j.jconrel.2025.114203 | 2025 | | |
| Metabolism | NIR-activated nanodisguisers for targeted bactericidal action and enhanced electron transfer in periodontitis treatment. | Qi M, Ding Q, Shi Y, Wang K, Liu J, Zhou J, Zhang W, Liu C, Liang S, Dong B, Kim JS, Wang L. | Biomaterials | 10.1016/j.biomaterials.2025.123487 | 2026 | |
| A Systematic Review and Meta-Analysis of Animal Models on the Possible Link Between Periodontitis and Inflammatory Bowel Diseases. | Akash H, Pandis N, Manschiebel W, Burisch J, Bertl K, Stavropoulos A. | Inflamm Bowel Dis | 10.1093/ibd/izaf087 | 2025 | | |
| Influence of Fusobacterium nucleatum on Tumor Necrosis Factor Alpha Therapy in Ulcerative Colitis. | Senyuz B, Unal NG, Yakut BD, Uzel A, Gunduz C, Susluer SY. | Mediators Inflamm | 10.1155/mi/5035877 | 2025 | | |
| Gut and oral microbial profile associations to oral cancer. | Nayyar J, Bedu-Ferrari C, Patangia D, Hurley E, Feeley L, Ross RP, Stanton C, Brady P. | J Dent | 10.1016/j.jdent.2025.105848 | 2025 | | |
| Bacteriophages for periodontal pathogens control: A systematic review. | Dallepiane FG, Nogueira MAC, Menezes Dos Anjos L, Melo GS, Henriques B, Fongaro G, Cruz ACC. | J Dent | 10.1016/j.jdent.2025.105960 | 2025 | | |
| Antibacterial and anticancer activities of rhizobacterial lipopeptides against carcinogenic bacteria. | Al-Hazmi NE. | Antonie Van Leeuwenhoek | 10.1007/s10482-025-02131-7 | 2025 | | |
| The influence of periodontal disease and periodontal treatment on colorectal cancer. | Rebersak UP, Brecelj E, Schara R. | Radiol Oncol | 10.2478/raon-2025-0025 | 2025 | | |
| Clinical Characteristics and Prognosis of Patients with Severe Pneumonia with Neurological Dysfunction: A Regional Multicenter Retrospective Study in Mainland China. | Zhu Y, Jia Y, Zhang C, Li H, Ding P, Huang L, Wang G, Cai H, Yu W. | Infect Drug Resist | 10.2147/idr.s537406 | 2025 | | |
| Periodontal Microbial Profiles Across Periodontal Conditions in Pediatric Subjects: A Narrative Review. | Di Spirito F, Di Palo MP, De Benedetto G, Piedepalumbo F, Galdi M, Cannata D, Cafa N, Contaldo M. | Microorganisms | 10.3390/microorganisms13081813 | 2025 | | |
| Fusobacterium nucleatum-derived 3-indolepropionic acid promotes colorectal cancer progression via aryl hydrocarbon receptor activation in macrophages. | Song Q, Jin Z, Zhang H, Hong K, Zhu B, Yin H, Yu B. | Chem Biol Interact | 10.1016/j.cbi.2025.111495 | 2025 | | |
| Gut microbiota as a mediator of cancer development and management: From colitis to colitis-associated dysplasia and carcinoma. | Dan W, Xiong C, Zhou G, Chen J, Pan F. | Biochim Biophys Acta Rev Cancer | 10.1016/j.bbcan.2025.189381 | 2025 | | |
| Oral Bacterial and Fungal Microbiome and Subsequent Risk for Pancreatic Cancer. | Meng Y, Wu F, Kwak S, Wang C, Usyk M, Freedman ND, Huang WY, Um CY, Gonda TA, Oberstein PE, Li H, Hayes RB, Ahn J. | JAMA Oncol | 10.1001/jamaoncol.2025.3377 | 2025 | | |
| Isolated Facial Vein Thrombophlebitis Caused by Fusobacterium nucleatum: A Lemierre-Variant Case. | Oska N, Peterson D, Brothers K, Maramraju R, Ayyad A, Hohmann B. | Case Rep Infect Dis | 10.1155/crdi/9938125 | 2025 | | |
| Eliminating intratumoral bacteria with cGAS-STING-activating nanodrug-bacteria biohybrids potentiates cancer immunotherapy. | Zhou X, Pan X, Shen Z, Kang R, Pang Y, Luo L, Liu F, Yu S, Zhang J, Shen Q. | Biomaterials | 10.1016/j.biomaterials.2025.123629 | 2026 | | |
| Nano-omics and nanomedicine target microbial carcinogenesis: Tumor microenvironment reprograming to clinical translation. | Kawuribi V, Xie Y, Xu H, Zhang Y, Zheng S. | Crit Rev Oncol Hematol | 10.1016/j.critrevonc.2025.104866 | 2025 | | |
| Metagenomic Signatures of Colorectal Cancer in the Jordanian Population: A Regional Case-Control Analysis Using 16S rRNA Profiling. | Alanagreh L, Mustafa MA, Al-Zghoul MB, Massadeh MI, Batiha O, Sughayer M, Almashakbeh RT, Abu Suilike HB, Tout FS, Alzoughool F. | Microorganisms | 10.3390/microorganisms13081963 | 2025 | | |
| The Involvement of Oral Pathogenic Bacteria, Fusobacterium nucleatum Subspecies animalis in the Pathogenesis of Human Esophageal Adenocarcinoma. | Kitano T, Okumura S, Matsumoto T, Tsunoda S, Nishigori T, Obama K, Hara E. | Gastro Hep Adv | 10.1016/j.gastha.2025.100660 | 2025 | | |
| Pathogenicity | Gram-negative intratumoral bacteria mediate lymph node metastasis through LPS-TLR4/MAPK signaling pathway in cervical cancer. | Liu Y, Ma P, Liu D, Liu Y, Ran Z, Yang L, Xu L, Yin W, Chen F, Li L, Lu Y. | J Infect | 10.1016/j.jinf.2025.106532 | 2025 | |
| Anti-inflammatory, antioxidant, and antimicrobial evaluation of morin. | Sales LS, Hewitt B, Muchova M, Brighenti FL, Kuehne SA, Grant MM, Milward MR. | Arch Oral Biol | 10.1016/j.archoralbio.2025.106343 | 2025 | | |
| Pathogenicity | Examining the Role of Virulence Proteins From Pathogenic Anaerobes in the Initiation of Colorectal Cancer. | Gopalakrishnan V, Saravanan V, Mahendran MIMS, Boopathy V, Vaithianathan R, Srinivasan S, Krishnamurthy S. | APMIS | 10.1111/apm.70041 | 2025 | |
| Oral Microbiome as a Biomarker and Therapeutic Target in Head and Neck Cancer: Current Insights and Future Directions. | Ahmad S, Jayamanne D, Bergamin S, Lawless A, Guminski A, Lee A, Yuile A, Wheeler H, Eade T, Back M, Molloy M, Oh B. | Cancers (Basel) | 10.3390/cancers17162667 | 2025 | | |
| Microbiota-driven epigenetic modifications in gastrointestinal cancer: Implications for pathogenesis and therapeutic strategies. | Rahimi-Kolour H, Eshaghi HS, Shams E, Sanjabi F, Nobili S, Raeisi H, Sadeghi A, Nazemalhosseini-Mojarad E, Fatemi N. | World J Microbiol Biotechnol | 10.1007/s11274-025-04457-w | 2025 | | |
| Systematic review of silver and vanadium-based antibiofilm agents: mechanisms and efficacy in oral biofilms. | Carvalho-Silva JM, Dos Reis AC. | Future Microbiol | 10.1080/17460913.2025.2520080 | 2025 | | |
| Fusobacterium nucleatum modulates the Wnt/beta-catenin pathway in colorectal cancer development. | Mondal T, Chattopadhyay D, Saha Mondal P, Das S, Mondal A, Das A, Samanta S, Saha T. | Int J Biol Macromol | 10.1016/j.ijbiomac.2025.140196 | 2025 | | |
| Carcinogenetic mechanisms employed by the oral microbiome: A narrative review. | Menghani SV. | Am J Med Sci | 10.1016/j.amjms.2025.01.001 | 2025 | | |
| Prognostic Impact of Non-Impacted Third Molar Extraction on Non-Surgical Periodontal Therapy for Adjacent Second Molars: A Prospective Split-Mouth Study. | Gao R, Qu HL, Tian Y, Sun LJ, He XT, Tian BM, Yin Y, Chen FM, Wu RX. | J Clin Periodontol | 10.1111/jcpe.70010 | 2025 | | |
| Multifunctional Three-Layer Collagen-Based Membrane for Periodontal Guided Tissue Regeneration. | Takallu S, Karimi Z, Khorshidi H, Bazargani A, Bigham-Sadegh A, Torabi Nezhad S, Mirzaei E. | ACS Biomater Sci Eng | 10.1021/acsbiomaterials.5c00613 | 2025 | | |
| Combination of neovestitol and vestitol impair the subgingival multispecies biofilm development. | Pingueiro JMS, Feres M, Macedo TT, Paulo Gomes APA, Vilela FMS, Bueno MR, da Silva LDA, Silva APS, Alencar SM, Rosalen PL, Bueno-Silva B. | Biofouling | 10.1080/08927014.2025.2551066 | 2025 | | |
| Multi-omics network toxicology reveals the role of benzo[a]pyrene in ovarian cancer: Integrating gut microbiota dynamics and Mendelian randomization. | Huang J, Yang Q, Zeng L, Deng K. | Ecotoxicol Environ Saf | 10.1016/j.ecoenv.2025.118601 | 2025 | | |
| In Vitro Comparison of Antibacterial Properties of Various Mouth Rinses in Public Health Settings. | Prajapati UH, Mall BB, Sharma R, George B, Raj A, Sayeeganesh N. | J Pharm Bioallied Sci | 10.4103/jpbs.jpbs_835_25 | 2025 | | |
| A Dual-Network Thermosensitive Tricalcium Silicate-Based Pulp Capping Agent Based on Sodium Alginate and Modified Chitosan. | Song J, Zhou Y, Hu H, Ran S, Zhang Y. | ACS Appl Bio Mater | 10.1021/acsabm.5c00670 | 2025 | | |
| Potential of novel antibacterial bio-adhesive for the treatment of periodontitis. | Xu Y, Zhou Y, Meng S, Zhou C, Yang N, Bao L, Lu W. | Biomed Mater | 10.1088/1748-605x/adc6df | 2025 | | |
| Emerging New Treatments for Colon Cancer. | Adedayo SI, Riethmacher E. | Curr Med Chem | 10.2174/0109298673372776250505155945 | 2025 | | |
| Bacterial translocation signatures and subgingival microbiome in individuals with periodontitis. | Britos M, Hernandez M, Fernandez A, Pellegrini E, Chaparro L, Chaparro A, Suarez LJ, Hoare A, Hernandez-Rios P. | Clin Oral Investig | 10.1007/s00784-025-06363-9 | 2025 | | |
| Multifunctional nanodrug for simultaneously combating chemoresistance and immunosuppression in Fusobacterium nucleatum-associated colorectal cancer. | Li X, Wu M, Wu Y, Xin Y, Gao L, Elsabahy M, Wang X, Zhang J, Qu X, Gao H. | Acta Biomater | 10.1016/j.actbio.2025.02.013 | 2025 | | |
| Dental extraction-associated cerebral abscess caused by Parvimonas micra. | Asagiri H, Tsutsumi S, Uwabe K, Sugiyama N, Ueno H, Ishii H. | Surg Neurol Int | 10.25259/sni_932_2025 | 2025 | | |
| Diagnostic utility of next-generation sequencing in neurological infections: Two cases in point. | Kandikuppa RT, Krishna V, Sethuraman N, Sridhar A, Paramasivam S. | Diagn Microbiol Infect Dis | 10.1016/j.diagmicrobio.2025.116713 | 2025 | | |
| Activation of the tumor cell-intrinsic STING pathway induced by Fusobacterium nucleatum is associated with poor prognosis in esophageal cancer patients. | Nakajima S, Saito K, Fukai S, Sakuma M, Matsuishi A, Kanoda R, Maruyama Y, Suzuki H, Okayama H, Saito M, Mimura K, Nirei A, Kikuchi T, Hanayama H, Saze Z, Momma T, Nishiyama K, Suzutani T, Kono K. | Esophagus | 10.1007/s10388-025-01112-z | 2025 | | |
| The intervention of B. longum metabolites in Fnevs' carcinogenic capacity: A potential double-edged sword. | Xu J, Wu X, Yang L, Xu X. | Exp Cell Res | 10.1016/j.yexcr.2025.114407 | 2025 | | |
| Investigation of the relationship between Fusobacterium nucleatum presence and inflammatory mediator expression in Kazakhstani patients with colorectal cancer. | Kulmambetova G, Kurentay B, Gusmaulemova A, Bayanbek D, Mamlin M, Khamzina S, Shalekenov S, Kozhakhmetov A. | Front Microbiol | 10.3389/fmicb.2025.1699745 | 2025 | | |
| Phylogeny | Diagnosis of Pelvic Actinomycosis and Fusobacterium Infection Using 16S rRNA Gene Analysis for Formalin-Fixed Paraffin-Embedded (FFPE) Tissue After Intrauterine Device (IUD) Removal. | Kitakura E, Onuma T, Orisaka M, Yoshida Y. | Cureus | 10.7759/cureus.91208 | 2025 | |
| Case report: Laboratory diagnosis methods on brain abscess pathogens caused by anaerobic species and Streptococci constellatus. | Li Y, Jiang X, Ji J, Yao B, Zhao F, Zhang J, Yu Y, Fu Y. | IDCases | 10.1016/j.idcr.2025.e02373 | 2025 | | |
| Evaluation of Microbiological Flora in Endo-Perio Lesions before and after Treatment. | Bagde H, Karki RS, Husain S, Khan S, Haripriya V, Purwar P. | J Pharm Bioallied Sci | 10.4103/jpbs.jpbs_271_25 | 2025 | | |
| Multi-cohort analysis reveals colorectal cancer tumor location-associated fecal microbiota and their clinical impact. | Lin Y, Lau HC, Liu C, Ding X, Sun Y, Rong J, Zhang X, Wang L, Yuan K, Miao Y, Wu WK, Wong SH, Sung JJ, Yu J. | Cell Host Microbe | 10.1016/j.chom.2025.03.012 | 2025 | | |
| Fusobacterium nucleatum-driven CX3CR1+ PD-L1+ phagocytes route to tumor tissues and reshape tumor microenvironment. | Chen F, Guo S, Li Y, Lu Y, Liu L, Chen S, An J, Zhang G. | Gut Microbes | 10.1080/19490976.2024.2442037 | 2025 | | |
| Hypopituitarism secondary to internal carotid artery pseudoaneurysm following Lemierre's syndrome caused by Fusobacteriumnucleatum. | Gruetzmacher C, Nakaguma M, Jallad RS, Craveiro FL, da Silva Tenorio AP, Padula M, Batista RL. | Anaerobe | 10.1016/j.anaerobe.2025.102942 | 2025 | | |
| Pathogenicity | Oral Microbiome-Mediated Carcinogenesis in Oral Cavity Cancer: A Narrative Review. | Semiz V, Aksoy RA, Altun Z. | Cureus | 10.7759/cureus.83242 | 2025 | |
| Fusobacterium nucleatum-Induced Pyopneumothorax: A Rare but Serious Clinical Entity. | Chen Y, Yu C, Chai J, Chai M, Xiao Y, Loong H, Xu D, Wang L. | Infect Drug Resist | 10.2147/idr.s530213 | 2025 | | |
| Oral microbiota in colorectal cancer: Unraveling mechanisms and application potential. | Zhang X, Chen Y, Xia Y, Lin S, Zhou X, Pang X, Yu J, Sun L. | Life Sci | 10.1016/j.lfs.2025.123462 | 2025 | | |
| Computational Screening of Novel Nitroimidazole Candidates: Targeting Key Enzymes of Oral Anaerobes for Anti-parasitic Potential. | Lanez T, Lanez M, Lanez R, Laanez E, Talbi-Lanez B. | Curr Drug Discov Technol | 10.2174/0115701638326365241029080310 | 2025 | | |
| Bacteria-tumor symbiosis destructible novel nanocatalysis drug delivery systems for effective tumor therapy. | Zang J, Yin F, Liu Z, Li F, Zhang Y. | Nanomedicine (Lond) | 10.1080/17435889.2024.2443388 | 2025 | | |
| Pathogenicity | Tumor-infiltrating bacteria disrupt cancer epithelial cell interactions and induce cell-cycle arrest. | Galeano Nino JL, Ponath F, Ajisafe VA, Becker CR, Kempchinsky AG, Zepeda-Rivera MA, Gomez JA, Wu H, Terrazas JG, Bouzek H, Cromwell E, Chanana P, Wong M, Damania A, White MG, You YN, Kopetz S, Ajami NJ, Wargo JA, Johnston CD, Bullman S. | Cancer Cell | 10.1016/j.ccell.2025.09.010 | 2025 | |
| Genome sequences of eight Fusobacterium watanabei sp. isolates. | Zepeda-Rivera MA, Ponath F, Lewis KN, Gavate RP, Dewhirst FE, Tomida J, Kawamura Y, Tanaka K, Bullman S, Johnston CD. | Microbiol Resour Announc | 10.1128/mra.00132-25 | 2025 | | |
| Multi-omics characterization of gut microbiota and fecal and plasma metabolites in patients with primary Sjögren's syndrome. | Liu Y, Wang Q, Zhang Y, Duo R, Bian X, Tian J, Hao J, Zheng J, Shen H. | Clin Rheumatol | 10.1007/s10067-025-07642-2 | 2025 | | |
| Fusobacteriumnucleatum: Pathophysiological and Clinical Involvement in Inflammatory Bowel Diseases, Colorectal Cancer and Cardiovascular Diseases. | Quagliariello V, Forte P, Ciappina G, Colarusso L, Giorgi C, Fiorica F, Bottari A, Di Mauro G, Maurea N, Berretta M. | Cancers (Basel) | 10.3390/cancers17203348 | 2025 | | |
| Tumor and intratumoral pathogen cascade-targeting photothermal nanotherapeutics for boosted immunotherapy of colorectal cancer. | Xin Y, Yu Y, Wu M, Su M, Elsabahy M, Qu X, Gao H. | J Control Release | 10.1016/j.jconrel.2025.01.048 | 2025 | | |
| Fusobacterium nucleatum Enrichment in Colorectal Tumor Tissue: Associations With Tumor Characteristics and Survival Outcomes. | Phipps AI, Hill CM, Lin G, Malen RC, Reedy AM, Kahsai O, Ammar H, Curtis K, Ma N, Randolph TW, Ma J, Ogino S, Newcomb PA, Hullar MA. | Gastro Hep Adv | 10.1016/j.gastha.2025.100644 | 2025 | | |
| Pathogenicity | Decrease from main root canal and intratubular Fusobacterium nucleatum and its endotoxin after ultrasonic activation of conventional and alternative irrigation solutions. | Barros MC, Feliz Pedrinha V, Eduardo Oliveira F, Marcucci MC, Gomes BPFA, Oliveira LD, Andrade FB. | Biofouling | 10.1080/08927014.2024.2426765 | 2024 | |
| Dentures and the oral microbiome: Unraveling the hidden impact on edentulous and partially edentulous patients - a systematic review and meta-analysis. | Madhan Kumar S, Natarajan S, Ks S, Sundarajan SK, Natarajan P, Arockiam AS. | Evid Based Dent | 10.1038/s41432-025-01149-0 | 2025 | | |
| Letter to the Editor - "Intratumoral Fusobacterium nucleatum associates with advanced-stage colorectal cancer and poor prognosis in a Chinese cohort". | Shi Y, Yan F, Wang W, Li X. | Int J Surg | 10.1097/js9.0000000000002655 | 2025 | | |
| Effectiveness of Nano-hydroxyapatite-coated Implants against Peri-implantitis Bacteria. | Fazal I, Bangia V, Yadav A, Batra D, Kar S, Gupta S. | J Pharm Bioallied Sci | 10.4103/jpbs.jpbs_162_25 | 2025 | | |
| Integrated Microbiota-Bile Acid Analysis as Potential NonInvasive Biomarkers for Ulcerative Colitis Staging Diagnose. | He T, Wang Y, Zhao L, Che Y, Zhang L, Zeng Y, Shen H, Hao H, Cao L. | FASEB J | 10.1096/fj.202501078r | 2025 | | |
| Pathogenicity | The Oral-Gut Microbiota Axis Across the Lifespan: New Insights on a Forgotten Interaction. | Azzolino D, Carnevale-Schianca M, Santacroce L, Colella M, Felicetti A, Terranova L, Castrejon-Perez RC, Garcia-Godoy F, Lucchi T, Passarelli PC. | Nutrients | 10.3390/nu17152538 | 2025 | |
| Bacterial DNA in patients with ruptured intracranial aneurysms: Investigating the potential role of periodontal and gut microbiota. | Rabelo NN, Brenner LO, Coelho ACSDS, Telles JPM, Dourado JPO, Hora DABD, Pallos D, Braz-Silva PH, Teixeira MJ, Figueiredo EG. | Clin Neurol Neurosurg | 10.1016/j.clineuro.2025.108771 | 2025 | | |
| Tumor Tissue Microbiota in Colorectal Cancer: PCR Profile of FFPE Blocks in Associations with Metastatic Status. | Shakhpazyan NK, Mikhaleva LM, Sadykhov NK, Midiber KY, Buchaka AS, Gioeva ZV, Mikhalev AI, Bedzhanyan AL. | Cells | 10.3390/cells14191508 | 2025 | | |
| The Gut Microbiome in Early-Onset Colorectal Cancer: Distinct Signatures, Targeted Prevention and Therapeutic Strategies. | Lauricella S, Brucchi F, Cirocchi R, Cassini D, Vitellaro M. | J Pers Med | 10.3390/jpm15110552 | 2025 | | |
| The role of intratumoral microbiome in the occurrence, proliferation, metastasis of colorectal cancer and its underlying therapeutic strategies. | Liao K, Wen J, Liu Z, Zhang B, Zhang X, Fu Y, Zhang W, Hu H, Ai K, Zhu W, Xia M, Lai Y, Qian Y, Xu Y, Sun F, Zhang L, Zhong Q, Huang B, Wang X. | Ageing Res Rev | 10.1016/j.arr.2025.102820 | 2025 | | |
| PMA-qPCR to quantify viable cells in multispecies oral biofilm after disinfectant treatments. | Schwendener S, Flury M, Jenzer J, Thurnheer T, Karygianni L. | Biofilm | 10.1016/j.bioflm.2025.100281 | 2025 | | |
| Hydrophobic 2-methacryloyloxyethyl phosphorylcholine polymer inhibits peri-implantitis-causing bacterial adhesion on titanium materials. | Akizuki M, Murakami K, Sekine K, Murakami A, Kobayashi K, Matsuda M, Matsumoto H, Harata E, Hamada K, Enggardipta RA, Fujii H, Yumoto H. | J Appl Microbiol | 10.1093/jambio/lxaf033 | 2025 | | |
| Pathogenicity | Integrated metagenomics and transcriptomics analysis reveals pathways associated with oral periapical lesions formation and progression. | Altaie AM, Venkatachalam T, Patil K, Al-Marzooq F, Rawat SS, Qabbani AA, Alsaegh MA, Samaranayake LP, Soliman SSM, Hamoudi R. | Curr Res Microb Sci | 10.1016/j.crmicr.2025.100443 | 2025 | |
| Different impacts of intestinal microbiota and lifestyle factors on advanced adenoma and colorectal cancer risk. | Zha L, Shimomura Y, Kitamura T, Komukai S, Narii N, Komatsu M, Shiba S, Mizutani S, Yamada T, Yachida S, Sobue T. | Eur J Cancer Prev | 10.1097/cej.0000000000000974 | 2025 | | |
| Fusobacterium nucleatum in the oral cavity is associated with cerebral small vessel disease in patients with ischemic stroke. | Aoki S, Nishi H, Shiga Y, Nezu T, Eto F, Imamura E, Shimomura R, Kawada-Matsuo M, Komatsuzawa H, Kawaguchi H, Maruyama H. | J Stroke Cerebrovasc Dis | 10.1016/j.jstrokecerebrovasdis.2024.108183 | 2025 | | |
| Bridging oral and systemic health: exploring pathogenesis, biomarkers, and diagnostic innovations in periodontal disease. | Foroughi M, Torabinejad M, Angelov N, Ojcius DM, Parang K, Ravnan M, Lam J. | Infection | 10.1007/s15010-025-02568-y | 2025 | | |
| The Oral Microbiome and Cancer. | Deng J, Sun C, Xu G, Wang B, Tzortzopoulou E, Deng D, Giovannetti E. | Adv Exp Med Biol | 10.1007/978-3-031-79146-8_10 | 2025 | | |
| The role of Fusobacterium nucleatum in the pathogenesis of colon cancer. | Hong BY, Chhaya A, Robles A, Cervantes J, Tiwari S. | J Investig Med | 10.1177/10815589241277829 | 2024 | | |
| The periodontal pathogen Fusobacterium nucleatum is associated with disease severity in multiple sclerosis. | Naito H, Nakamori M, Nishi H, Toko M, Muguruma T, Yamada H, Sugimoto T, Yamazaki Y, Ochi K, Kawaguchi H, Maruyama H. | Sci Rep | 10.1038/s41598-025-22266-x | 2025 | | |
| Fusobacterium nucleatum promotes PD-L1 expression in cancer cells to evade CD8+ T cell killing in breast cancer. | Guo J, Zhu P, Li J, Xu L, Tang Y, Liu X, Guo S, Xia J. | Hum Immunol | 10.1016/j.humimm.2024.111168 | 2024 | | |
| Clinical and Microbiological Effectiveness of Diode Laser for Treating Patients with Stage II Grade A Periodontitis Patients: Split-Mouth Study. | Abd El Mageed MH, Yousief SA, Alanazi S, Edrees MF, Abushama AA, Mwafey IM, Mekkey MAM, Barakat A, Abdelglel AMS, ElHaddad SA. | Photobiomodul Photomed Laser Surg | 10.1089/photob.2024.0118 | 2025 | | |
| Oral health promotion of flavonoids from Scutellaria baicalensis. | Cai BX, Wu QY, Huang JL, Wu J, Yu Y, Xiao L, Cai XH. | J Asian Nat Prod Res | 10.1080/10286020.2024.2428797 | 2025 | | |
| Dynamic changes of dental plaque and saliva microbiota in OSCC progression. | Zhang M, Zhang H, Hong A, Huang J, Yang L, Long Y, Yu Z. | Clin Oral Investig | 10.1007/s00784-025-06391-5 | 2025 | | |
| Engineering nanoplatforms of bacterial outer membrane vesicles to overcome cancer therapy resistance. | Chai QQ, Li D, Zhang M, Gu YW, Li AX, Wu X, Liu XY, Liu JY. | Drug Resist Updat | 10.1016/j.drup.2025.101277 | 2025 | | |
| Remodeling the Inflammatory and Immunosuppressive Tumor Microenvironment for Enhancing Antiangiogenic Gene Therapy of Colorectal Cancer. | Jiazhen N, Meihui S, De-E L, Na L, Youtao X, Qixian C, Yunjian Y, Feihe M, Mahmoud E, Hui G. | Adv Healthc Mater | 10.1002/adhm.202402887 | 2025 | | |
| The antibacterial and antibiofilm role of cannabidiol against periodontopathogenic bacteria. | Santos ALO, Santiago MB, Silva NBS, Souza SL, Almeida JMD, Martins CHG. | J Appl Microbiol | 10.1093/jambio/lxae316 | 2025 | | |
| Microbiological Insights and Diagnostic Approaches in Endo-Perio Lesions. | Kumari R, Suhagia B, Maheshwari R, Singh M. | J Pharm Bioallied Sci | 10.4103/jpbs.jpbs_533_25 | 2025 | | |
| Antibacterial efficacy and molecular docking analysis of Zingiber offinale and Allium sativum against Fusobacterium nucleatum - An in vitro study. | Jayakumar S, Subramanian A, Sabarinathan S, Shalini H, John BM, Saravanan R. | J Conserv Dent Endod | 10.4103/jcde.jcde_416_25 | 2025 | | |
| [Fusobacterium nucleatum upregulates ABCG2 by activating the E-cadherin/beta-catenin signaling pathway to promote oxaliplatin resistance in colorectal cancer]. | Xu FQ, Li BW, Liu Y, Wei YW. | Zhonghua Zhong Liu Za Zhi | 10.3760/cma.j.cn112152-20240719-00297 | 2025 | | |
| Utilizing a naturopathic mouthwash with selective antimicrobial effects against multispecies oral biofilms for prevention of dysbiosis. | Siddiqui DA, Tsai YC, Giron Bastidas J, Jazaeri MS, Kotsakis GA. | Front Oral Health | 10.3389/froh.2025.1529061 | 2025 | | |
| Synthesis of Surface-Charged IGF-1 Loaded PLGA Nanoparticles and Assess Dual Antimicrobial and Osteogenic Effects for Peri- Implant Bone Health: An In-Vitro Study. | Raza FB, Vaidyanathan AK, Kandasamy R, Krishnaswami V, Vijayaraghavalu S. | Int J Oral Maxillofac Implants | 10.11607/jomi.11268 | 2025 | | |
| Abscesses of the spine and iliac fossa caused by infection with the opportunistic bacterium Fusobacterium nucleatum. | Gu Y, Zhou Y, Hu T, Zhao H, Wang Y, He Y. | IDCases | 10.1016/j.idcr.2025.e02205 | 2025 | | |
| Periodontitis and Oral Bacteria Related to Rheumatoid Arthritis: A Case-Control Study. | Hashimoto H, Nonoyama T, Takami Y, Hashimoto S, Shimazaki Y. | Int Dent J | 10.1016/j.identj.2025.103856 | 2025 | | |
| Detection of Amyloid-beta Peptides in Gingival Crevicular Fluid and Its Effect on Oral Pathogens. | Liao Y, Chen HW, Qiu C, Shen H, He ZY, Song ZC, Zhou W. | Mol Oral Microbiol | 10.1111/omi.12488 | 2025 | | |
| Association of Fusobacterium nucleatum Levels by ddPCR in Oral Rinse Samples With Periodontal Disease in Oral Squamous Cell Carcinoma Patients and in Controls. | Fernandes BB, Datorre JG, Vazquez FL, Peters ACC, Coracin FL, Reis RM, Arantes LMRB, Gama RR. | J Oral Pathol Med | 10.1111/jop.13580 | 2024 | | |
| Fusobacterium nucleatum as an Emerging Culprit in Brain Abscesses: A Narrative Synthesis of 25 Years of Clinical and Diagnostic Data. | Ismail F, Mansoor U, Mehmood Qadri H, Zaman M, Ali A, Asif MA, Kaleem M, Khan H, Bashir RA, Irshad S, Bashir A. | Cureus | 10.7759/cureus.89421 | 2025 | | |
| Gelatin methacryloyl @MP196/exos hydrogel induced neutrophil apoptosis and macrophage M2 polarization to inhibit periodontal bone loss. | Zhuo H, Zhang S, Wang H, Deng J, Zhang X. | Colloids Surf B Biointerfaces | 10.1016/j.colsurfb.2024.114466 | 2025 | | |
| Unveiling the Hidden Links: Periodontal Disease, Fusobacterium Nucleatum, and Cancers. | Akbari E, Epstein JB, Samim F. | Curr Oncol Rep | 10.1007/s11912-024-01591-w | 2024 | | |
| The influence of microorganisms on bone homeostasis in apical periodontitis. | Pan D, Hao Y, Tao Y, Li B, Cheng L. | Arch Oral Biol | 10.1016/j.archoralbio.2024.106153 | 2025 | | |
| Comparative insights into Fusobacterium nucleatum and Helicobacter pylori in human cancers. | Gusmaulemova A, Kurentay B, Bayanbek D, Kulmambetova G. | Front Microbiol | 10.3389/fmicb.2025.1677795 | 2025 | | |
| Saccharibacteria (TM7) in saliva and subgingival microbiome as a predictor for gingivitis in individuals with type2 diabetes evaluated by qPCR. | Bachtiar BM, Tahapary DL, Fath T, Theodorea CF, Haerani N, Soeroso Y, Shahab SN, Wildan A, Runtu FMJG, Tadjoedin FM, Ayuningtyas D, Amir L, Bachtiar EW. | Front Dent Med | 10.3389/fdmed.2025.1550936 | 2025 | | |
| Pathogenicity | Polymicrobial Pyogenic Liver Abscess Without Classical Risk Factors: A Case Report of Streptococcus constellatus and Fusobacterium nucleatum Infection. | Barron DW, Wallace SG, Rappaport DE, Kelley JM, Martini WA. | Cureus | 10.7759/cureus.90195 | 2025 | |
| Detection and quantification of Fusobacterium nucleatum and Porphyromonas gingivalis in salivary samples of gutka and non-gutka users- 'A pilot study'. | Annegowda VM, Satelur KP, Shekar BCT, Rao K. | J Oral Maxillofac Pathol | 10.4103/jomfp.jomfp_17_25 | 2025 | | |
| New Electron-Transfer Chain to a Flavodiiron Protein in Fusobacterium nucleatum Couples Butyryl-CoA Oxidation to O2 Reduction. | Bystrom LT, Wolthers KR. | Biochemistry | 10.1021/acs.biochem.4c00279 | 2024 | | |
| Periodontal Status and Gingival Crevicular Fluid Fusobacterium nucleatum and Cathepsin K Assessment in Patients with Gastric Cancer. | Nicolae FM, Cucu M, Ramboiu S, Boldeanu VM, Turcu-Stiolica A, Surlin VM, Gheorghe DN, Popescu DM, Strambu VDE, Petre R, Didilescu AC, Surlin P. | J Clin Med | 10.3390/jcm14196768 | 2025 | | |
| Rare Case of Focal Organising Pneumonia With Extension to Interlobar Space and Adjacent Lobe Initially Suspected as Lung Cancer. | Koike S, Shiina T, Takasuna K, Kato A, Komatsu K, Nakamura T. | Respirol Case Rep | 10.1002/rcr2.70144 | 2025 | | |
| The Norepinephrine-QseC Axis Aggravates F. nucleatum-associated Colitis Through Interkingdom Signaling. | Zhang L, Chen G, Zeng X, Yue H, Zheng Q, Hu Q, Tian Q, Liang L, Zhao X, Yang Z, Bai H, Liu Y, Zhao M, Fu X. | Inflamm Bowel Dis | 10.1093/ibd/izae063 | 2024 | | |
| Impact of Fusobacterium nucleatum on immune cell interactions and gene expression in colorectal cancer: a retrospective cohort study. | Heregger R, Huemer F, Greil R, Canadas-Ortega M, Posselt G, Ijsselsteijn ME, Plattner C, Rieder D, Trajanoski Z, Krogsdam A, Klieser E, Neureiter D, Wessler S, Weiss L. | Front Immunol | 10.3389/fimmu.2025.1629014 | 2025 | | |
| Identification and characterisation of vaginal bacteria-glycan interactions implicated in reproductive tract health and pregnancy outcomes. | Tajadura-Ortega V, Chai W, Roberts LA, Zhang Y, Di Maio A, Decout AC, Pinheiro BA, Palma AS, De Nicola G, Riaposova L, Gimeno-Molina B, Lee YS, Cao H, Piskarev V, Akune Y, Costa TRD, Amin H, Sykes L, Bennett PR, Marchesi JR, Feizi T, Liu Y, MacIntyre DA. | Nat Commun | 10.1038/s41467-025-60404-1 | 2025 | | |
| An Overview of the Dichotomous Role of Microbiota in Cancer Progression and Management. | Jain P, Mohapatra S, Farooq U, Hassan N, Mirza MA, Iqbal Z. | Curr Cancer Drug Targets | 10.2174/0115680096282503240124104029 | 2025 | | |
| From Biofilm to Breath: The Role of Lacticaseibacillus paracasei ET-22 Postbiotics in Combating Oral Malodor. | Liu Y, Fang B, Wuri G, Lan H, Wang R, Sun Y, Zhao W, Hung WL, Zhang M. | J Agric Food Chem | 10.1021/acs.jafc.4c07381 | 2024 | | |
| Matrix-Insensitive Sensor Arrays via Peptide-Coated Nanoparticles: Rapid Saliva Screening for Pathogens in Oral and Respiratory Diseases. | Lam B, Amer L, Thompson E, Clark AE, Garretson AF, Carlin AF, Chen C, Retout M, Jokerst JV. | ACS Appl Mater Interfaces | 10.1021/acsami.4c15662 | 2024 | | |
| Phylogeny | Alterations of oral microbiota in young children with autism: Unraveling potential biomarkers for early detection. | Tang JW, Hau CC, Tong WM, Watt RM, Yiu CKY, Shum KK. | J Dent | 10.1016/j.jdent.2024.105486 | 2025 | |
| Gastric cancer-associated bacteria exhibit distinct butyrate and pyruvate metabolism: a metabolomic analysis of F. nucleatum, N. subflava, and H. pylori. | Niikura R, Hayakawa Y, Mukai T, Kato Y, Yoshida N, Fujishiro M. | BMC Microbiol | 10.1186/s12866-025-04466-7 | 2025 | | |
| Nicotine promotes pathogenic bacterial growth and biofilm formation in peri-implant. | Hu R, Qian H, Wang X, Peng B, Huang D. | J Med Microbiol | 10.1099/jmm.0.001897 | 2024 | | |
| The role of Fusobacterium nucleatum in cancer and its implications for clinical applications. | Luo W, Han J, Peng X, Zhou X, Gong T, Zheng X. | Mol Oral Microbiol | 10.1111/omi.12475 | 2024 | | |
| The relationship between pathogenic bacteria and different stages of colorectal cancer. | Nezhadi J, Kafil HS, Sadrkabir M, Mahdavi F, Moaddab SY, Nouri R, Mohammadzadeh-Asl Y, Sattarpour S, Rezaee MA. | Lett Appl Microbiol | 10.1093/lambio/ovaf017 | 2025 | | |
| Letter to the Editor: Colorectal cancer the immune microenvironment and the gut microbiota - new perspectives, challenges, and opportunities. | Zhao X, Li X, Wu G, Wu G. | Int J Surg | 10.1097/js9.0000000000002755 | 2025 | | |
| Fusobacterium nucleatum: a transboundary pathogen in host-microbiota networks. | Gao X, Cao F, Li Y, Huang J, Hu X, Li Z. | Gut Pathog | 10.1186/s13099-025-00775-4 | 2025 | | |
| Pathogenicity | Allyl isothiocyanate suppressed periodontal tissue destruction in mice via bacteriostatic and anti-inflammatory activities against Porphyromonas gingivalis. | Minato Y, Aoki-Nonaka Y, Lwin HY, Ando D, Warita Y, Matsugishi-Nasu A, Hiyoshi T, Takahashi N, Tabeta K. | Arch Oral Biol | 10.1016/j.archoralbio.2024.106118 | 2025 | |
| Fusobacterium nucleatum facilitates anti-PD-1 therapy in microsatellite stable colorectal cancer. | Wang X, Fang Y, Liang W, Wong CC, Qin H, Gao Y, Liang M, Song L, Zhang Y, Fan M, Liu C, Lau HC, Xu L, Li X, Song W, Wang J, Wang N, Yang T, Mo M, Zhang X, Fang J, Liao B, Sung JJY, Yu J. | Cancer Cell | 10.1016/j.ccell.2024.08.019 | 2024 | | |
| The intratumoral microbiota in breast cancer: from basic research to clinical translation. | Xu Y, Wang MC. | Gut Microbes | 10.1080/19490976.2025.2560695 | 2025 | | |
| Genetics | The Impact of Fusobacterium nucleatum and the Genotypic Biomarker KRAS on Colorectal Cancer Pathogenesis. | Dewan A, Tattoli I, Mascellino MT. | Int J Mol Sci | 10.3390/ijms26146958 | 2025 | |
| Subgingival Bacterial Microbiota Profile of People Living With HIV-1 Under HAART: A Systematic Review. | de Macedo TP, Goncalves C, Goncalves LS, Vidal PPP, Lima-Junior JDC, Vettore MV, Souza RC. | Spec Care Dentist | 10.1111/scd.70121 | 2025 | | |
| The Decontamination Effect of an Oscillating Chitosan Brush Compared With an Ultrasonic PEEK-Tip: An In Vitro Study Using a Dynamic Biofilm Model. | Khan SN, Ribeiro-Vidal H, Virto L, Bravo E, Nuevo P, Koldsland OC, Hjortsjo C, Sanz M. | Clin Oral Implants Res | 10.1111/clr.14360 | 2025 | | |
| Activatable Photoacoustic Probe for Imaging Infection: Gold Nanorod Dissociation In Vivo Reports Bacterial Protease Activity. | Retout M, Lepeintre V, Amer L, Yim W, Jokerst JV. | ACS Nano | 10.1021/acsnano.4c17874 | 2025 | | |
| The Molecular Interplay Between Oral Microbiome and Oral Cancer Pathogenesis. | Urzica RN, Cretu B, Caruntu A, Bucurica S, Farcasiu AT, Ciupescu LM, Scheau C, Caruntu C. | Int J Mol Sci | 10.3390/ijms262010212 | 2025 | | |
| The role and challenges of intratumoral microbiota in colorectal cancer immunotherapy. | Hao M, Xu H, Li M, Jiao D. | Front Pharmacol | 10.3389/fphar.2025.1634703 | 2025 | | |
| Fusobacterium nucleatum subsp. animalis comes to the spotlight in oral diseases. | C BG, Zhou P, Wu C. | Cell Host Microbe | 10.1016/j.chom.2024.03.009 | 2024 | | |
| Epithelial-mesenchymal transition in oral cancer cells induced by prolonged and persistent Fusobacterium nucleatum stimulation. | Nakano S, Kasai M, Nakamura K, Akasaka T, Yoshida Y, Suzuki S, Ohiro Y, Hasebe A. | J Oral Biosci | 10.1016/j.job.2024.05.006 | 2024 | | |
| Enhancing Colorectal Cancer Screening with Droplet Digital PCR Analysis of Fusobacterium nucleatum in Fecal Immunochemical Test Samples. | Datorre JG, Dos Reis MB, de Carvalho AC, Porto J, Rodrigues GH, Lima AB, Reis MT, Hirai W, Hashimoto CL, Guimaraes DP, Reis RM. | Cancer Prev Res (Phila) | 10.1158/1940-6207.capr-23-0331 | 2024 | | |
| Metronidazole-laden silk fibroin methacrylated scaffolds for managing periapical lesions. | Silverberg A, Cardoso LM, de Carvalho ABG, Dos Reis-Prado AH, Fenno JC, Dal-Fabbro R, Bottino MC. | Odontology | 10.1007/s10266-024-01023-y | 2025 | | |
| Association between Bacteroides fragilis and Fusobacterium nucleatum infection and colorectal cancer in Vietnamese patients. | Nguyen Duy T, Le Huy H, Dao Thanh Q, Ngo Thi H, Ngo Thi Minh H, Nguyen Dang M, Le Huu S, Ngo Tat T. | Anaerobe | 10.1016/j.anaerobe.2024.102880 | 2024 | | |
| Fusobacterium nucleatum-infected periodontitis promotes renal interstitial fibrosis in rats through the TGF-beta/SMAD2/3 and beta-catenin signaling pathways. | Chen P, Lin X, Zhang C, Xie Y, Guo Z, Ren F. | Gene | 10.1016/j.gene.2024.148729 | 2024 | | |
| Metabolism | Sialic acid metabolism of oral bacteria and its potential role in colorectal cancer and Alzheimer's disease. | Zhu J, Li M, Li J, Wu J. | Carbohydr Res | 10.1016/j.carres.2024.109172 | 2024 | |
| Cryptogenic Fusobacterium liver abscesses in two healthy, young adult males. | Josephs CA, Tucker AB, Everhart J, Fuerstenau N, Templeton-Jager T. | IDCases | 10.1016/j.idcr.2025.e02304 | 2025 | | |
| Digital PCR outperforms quantitative real-time PCR for the detection and quantification of major periodontal pathobionts. | Munjakovic H, Povsic K, Poljak M, Seme K, Gaspersic R, Skubic L. | J Oral Microbiol | 10.1080/20002297.2025.2537439 | 2025 | | |
| A Case of Acute Coalescent Mastoiditis With Early Diagnosis of Lupus Anticoagulant-Hypoprothrombinemia Syndrome Prompting Immediate Surgical Drainage. | Saito Y, Hasegawa M, Araki K. | Cureus | 10.7759/cureus.84336 | 2025 | | |
| Fusobacterium nucleatum and IL-32 co-predict nodal metastasis preoperatively in head and neck cancer. | Wang Z, Huang H, Yuan X, Hsueh C, Zhang M. | Transl Cancer Res | 10.21037/tcr-2024-2539 | 2025 | | |
| Tumor-associated microbiota: Multi-cancer landscape, mechanistic insights and clinical translation (Review). | Yang J, Dong Y, Chen Y, Liang H, Rong S, Liu Z, Lang Q. | Oncol Lett | 10.3892/ol.2025.15273 | 2025 | | |
| HutZ from Aliivibrio fischeri Inhibits HutW-Mediated Anaerobilin Formation by Sequestering Heme. | McGregor AK, Wolthers KR. | Biochemistry | 10.1021/acs.biochem.4c00624 | 2024 | | |
| Periodontal pathogen Fusobacterium nucleatum infection accelerates hepatic steatosis in high-fat diet-fed ApoE knockout mice by inhibiting Nrf2/Keap1 signaling. | Wu P, Bie M, Zhou J, Wang J, Zhao L. | J Periodontal Res | 10.1111/jre.13278 | 2024 | | |
| Intratumoral Fusobacterium nucleatum is associated with better cancer-specific survival in head and neck cancer patients. | Datorre JG, Dos Reis MB, Sorroche BP, Teixeira GR, Hatano SS, de Carvalho AC, Gama RR, Rebolho Batista Arantes LM, Reis RM. | J Oral Microbiol | 10.1080/20002297.2025.2487644 | 2025 | | |
| Chemical Synthesis of a Densely Functionalized Aminodisaccharide from Fusobacterium nucleatum ATCC 23726 O-Antigen. | Ding M, Qin C, Sun W, Tian G, Zou X, Hu J, Yin J. | Org Lett | 10.1021/acs.orglett.4c01344 | 2024 | | |
| Dencichine attenuates the virulence of Fusobacterium nucleatum by targeting hydrogen sulfide-producing enzyme. | Wang M, Chu W. | Int Microbiol | 10.1007/s10123-024-00539-1 | 2025 | | |
| The adhesin RadD enhances Fusobacterium nucleatum tumour colonization and colorectal carcinogenesis. | Zhang L, Leng XX, Qi J, Wang N, Han JX, Tao ZH, Zhuang ZY, Ren Y, Xie YL, Jiang SS, Li JL, Chen H, Zhou CB, Cui Y, Chen X, Wang Z, Zhang ZZ, Hong J, Chen HY, Jiang W, Chen YX, Zhao X, Yu J, Fang JY. | Nat Microbiol | 10.1038/s41564-024-01784-w | 2024 | | |
| Chemical, Antibacterial, and Cytotoxic Properties of Four Different Endodontic Sealer Leachates Over Time. | Chen JH, Raman V, Kuehne SA, Camilleri J, Hirschfeld J. | J Endod | 10.1016/j.joen.2024.08.015 | 2024 | | |
| A microfluidic co-culture model for investigating colonocytes-microbiota interactions in colorectal cancer. | Penarete-Acosta D, Stading R, Emerson L, Horn M, Chakraborty S, Han A, Jayaraman A. | Lab Chip | 10.1039/d4lc00013g | 2024 | | |
| Identification of oral bacteria as a new forensic tool for saliva detection. | Betser-Cohen G, Mayuoni-Kirsehenbaum L, Zubeidat K, Horev Y, Berchoer LE, Cohen A, Aframian D, Amiel M, Hovav AH. | Forensic Sci Int | 10.1016/j.forsciint.2024.112112 | 2024 | | |
| The gut microbiome and gastrointestinal cancers: mechanisms, biomarkers and therapeutic opportunities. | Makkar SK, Bishnupuri KS. | Front Physiol | 10.3389/fphys.2025.1676796 | 2025 | | |
| HPV status impacts oncobacteria abundance and prognostic relevance in head and neck squamous cell carcinoma. | Kerr TD, Silver NL, Duggal R, Dai J, Simmons H, Singh S, Shah AA, Fredenburg KM, Stacy AR, McGrail DJ. | Oncogene | 10.1038/s41388-025-03463-4 | 2025 | | |
| A gene delivery system with autophagy blockade for enhanced anti-angiogenic therapy against Fusobacterium nucleatum-associated colorectal cancer. | Li N, Yu Y, Chen Q, Niu J, Gao C, Qu X, Zhang J, Gao H. | Acta Biomater | 10.1016/j.actbio.2024.05.051 | 2024 | | |
| Metabolism | Antimicrobial effects of epigallocatechin-3-gallate, a catechin abundant in green tea, on periodontal disease-associated bacteria. | Higuchi M, Abiko Y, Washio J, Takahashi N. | Arch Oral Biol | 10.1016/j.archoralbio.2024.106063 | 2024 | |
| "Photo-Thermo-Electric" Dental Implant for Anti-Infection and Enhanced Osteoimmunomodulation. | Chen B, Wang W, Hu M, Liang Y, Wang N, Li C, Li Y. | ACS Nano | 10.1021/acsnano.4c05859 | 2024 | | |
| tNGS Reveals Predominant Mixed Viral Infections in a Multicenter Retrospective Study. | Zhang X, Tang R, Li X, Li L. | Infect Drug Resist | 10.2147/idr.s544262 | 2025 | | |
| Oral Microbiome as a Biomarker and Therapeutic Target in Head and Neck Cancer: Current Insights and Future Directions | Ahmad S, Jayamanne D, Bergamin S, Lawless A, Guminski A, Lee A, Yuile A, Wheeler H, Eade T, Back M, Molloy M, Oh B. | Cancers (Basel) | 2025 | | ||
| Phylogeny | Development of a multiplex PCR assay and quantification of microbial markers by ddPCR for identification of saliva and vaginal fluid. | Dass M, Ghai M. | Forensic Sci Int | 10.1016/j.forsciint.2024.112147 | 2024 | |
| Oral microbiota interactions with titanium implants: A pilot in-vivo and in-vitro study on the impact of peri-implantitis. | Sekar P, Rizvi Z, Abdullah N, Samsudin AR, Kheder W. | PLoS One | 10.1371/journal.pone.0321428 | 2025 | | |
| The outer membrane autotransporters Fap2 and CmpA facilitate specific coaggregation between Fusobacterium nucleatum and Aggregatibacter actinomycetemcomitans serotypes b and d. | Tanaka Y, Oogai Y, Matsumoto A, Noguchi K, Nakata M. | Appl Environ Microbiol | 10.1128/aem.01132-25 | 2025 | | |
| From obesity to cancer: Gut microbiome mechanisms, biomarkers, and U.S. public health strategies. | Moseeb HM, Aizaz MM, Aiza K, Hafsa TH, Sania M, Kamran Z, Shamama ZT, Usama AM, Maroof QP, Feroze F, Ahmed R, Ammara N, Mahima G. | Oncoscience | 10.18632/oncoscience.634 | 2025 | | |
| Tailoring zirconia surface topography via femtosecond laser-induced nanoscale features: effects on osteoblast cells and antibacterial properties. | Ghalandarzadeh A, Ganjali M, Hosseini M. | Biomed Mater | 10.1088/1748-605x/ad606f | 2024 | | |
| Pathogenicity | Effect of toxins from different periodontitis-associated bacteria on human platelet function. | Kobsar A, Wiebecke S, Weber K, Koessler A, Kuhn S, Boeck M, Zeller-Hahn J, Koessler J. | Mol Oral Microbiol | 10.1111/omi.12480 | 2024 | |
| Chemical Synthesis of an Orthogonally Protected 5,7-Diamino-3,5,7,9-tetradeoxy-d-glycero-l-gluco-2-nonulosonic Acid from N-Acetylneuraminic Acid. | Ding M, Sun W, Tian G, Zou X, Hu J, Qin C, Yin J. | Org Lett | 10.1021/acs.orglett.4c01861 | 2024 | | |
| Red-complex bacteria exhibit distinctly different interactions with human periodontal ligament stromal cells compared to Fusobacterium nucleatum. | Kendlbacher FL, Bloch S, Hager-Mair FF, Schaffer C, Andrukhov O. | Arch Oral Biol | 10.1016/j.archoralbio.2024.106004 | 2024 | | |
| Effect of 5-aminolevulinic acid-mediated photodynamic therapy against Fusobacterium nucleatum in periodontitis prevention. | Wang C, Nambu T, Takigawa H, Maruyama H, Mashimo C, Okinaga T. | J Photochem Photobiol B | 10.1016/j.jphotobiol.2024.112926 | 2024 | | |
| Significance of Fusobacterium nucleatum Combined with SFRP2 and SDC2 Gene Methylation Detection in Early Screening of Colorectal Cancer. | Zhong F, Wei X, Huang M, Yan H, Fu L, Liu X, Ru H, Mo X, Su Z, Yan L. | Pol J Microbiol | 10.33073/pjm-2025-018 | 2025 | | |
| An emerging antibacterial nanovaccine for enhanced chemotherapy by selectively eliminating tumor-colonizing bacteria. | Chen L, Kang Z, Shen J, Zhao R, Miao Y, Zhang L, Zheng Z, Zhang Z, Liu N, Wang C, Fang H, Zhou J, Wang Y, Liu Z, Yang Y, Chen Q. | Sci Bull (Beijing) | 10.1016/j.scib.2024.06.016 | 2024 | | |
| Effect of Chemotherapy on Fusobacterium nucleatum Abundance in Colorectal Cancer Patients: A Study on Relapsing Patients. | Zuraik AA, Daboul Y, Awama MA, Yazigi H, Kayasseh MA, Georges M. | Indian J Microbiol | 10.1007/s12088-024-01279-6 | 2024 | | |
| A Metal Chelation Therapy to Effectively Eliminate Breast Cancer and Intratumor Bacteria While Suppressing Tumor Metastasis by Copper Depletion and Zinc Ions Surge. | Xie Y, Wang J, Li L, Wang M, Sun J, Chang J, Lin J, Li C. | Angew Chem Int Ed Engl | 10.1002/anie.202417592 | 2025 | | |
| Oral and fecal microbiome alterations in pancreatic cancer: insights into potential diagnostic biomarkers. | Tavanaeian S, Feizabadi MM, Falsafi S, Aghdaei HA, Houri H. | BMC Microbiol | 10.1186/s12866-025-04344-2 | 2025 | | |
| Spatial Heterogeneity of Intratumoral Microbiota: A New Frontier in Cancer Immunotherapy Resistance. | Tan Q, Cao X, Zou F, Wang H, Xiong L, Deng S. | Biomedicines | 10.3390/biomedicines13051261 | 2025 | | |
| Screening inhibitors against the Ef-Tu of Fusobacterium nucleatum: a docking, ADMET and PBPK assessment study. | Alzamami A, Alturki NA, Khan K, Basharat Z, Mashraqi MM. | Mol Divers | 10.1007/s11030-024-10815-x | 2024 | | |
| Periodontal Pathobionts and Respiratory Diseases: Mechanisms of Interaction and Implications for Interdisciplinary Care. | Kim B, Han N. | Biomedicines | 10.3390/biomedicines13071741 | 2025 | | |
| Parallel Alterations in Gut and Tumor Microbiota in Pediatric Oncology: Potential Impacts on Disease Progression and Treatment Response. | Szabo PJ, Sagi V, Kassai LK, Kiss-Miki RM, Makra N, Szabo D, Garami M. | Cancers (Basel) | 10.3390/cancers17213426 | 2025 | | |
| Electrochemiluminescence Resonance Energy Transfer Biosensor for the Human-Associated Clade of Streptococcus suis Based on Prereduction-Enhanced Yttrium MOFs. | Hu C, Xiang H, Yin Y, Li J, Zhang Y, Huang X, Guo Y, He Y, Gao Y, Ren K, Han H, Wang W, Li J. | Anal Chem | 10.1021/acs.analchem.4c06560 | 2025 | | |
| Antimicrobial, antibiofilm, cytotoxicity, and substantivity of aged garlic extract against oral bacteria: an in-vitro study. | Sunil M, Kurangi B, Dodamani S, Khalil M, Chopra A. | BMC Complement Med Ther | 10.1186/s12906-025-05012-8 | 2025 | | |
| Fusobacterium Nucleatum in Colorectal Cancer: Relationship Among Immune Modulation, Potential Biomarkers and Therapeutic Implications. | Incognito D, Ciappina G, Gelsomino C, Picone A, Consolo P, Scano A, Franchina T, Maurea N, Quagliariello V, Berretta S, Ottaiano A, Berretta M. | Int J Mol Sci | 10.3390/ijms26199710 | 2025 | | |
| Phylogeny | Baseline Fusobacterium Abundance Predicts Ustekinumab Response in Crohn's Disease: A Prospective Microbiome Cohort Study. | Wang C, Hao Y, Liu Y, He L, Xu S, Zhang M, Wang X, Wang H. | Microb Biotechnol | 10.1111/1751-7915.70250 | 2025 | |
| Pathogenicity | Radicular Cysts and Periapical Granulomas: Data Documentation for 696 Cases and Findings on Fibrosis, and Porphyromonas gingivalis and Fusobacterium nucleatum in These Lesions. | Virkkunen S, Kaarela T, Laine M, Suominen A, Hagstrom J, Sorsa T, Haglund C. | Clin Exp Dent Res | 10.1002/cre2.70098 | 2025 | |
| The ways Fusobacterium nucleatum translocate to breast tissue and contribute to breast cancer development. | Guo X, Yu K, Huang R. | Mol Oral Microbiol | 10.1111/omi.12446 | 2024 | | |
| Fusobacterium nucleatum in Colorectal Cancer: Ally Mechanism and Targeted Therapy Strategies. | Lu J, Wei W, Zheng D. | Research (Wash D C) | 10.34133/research.0640 | 2025 | | |
| Biomimetic Nanovehicle-Enabled Targeted Depletion of Intratumoral Fusobacterium nucleatum Synergizes with PD-L1 Blockade against Breast Cancer. | Geng S, Guo P, Li X, Shi Y, Wang J, Cao M, Zhang Y, Zhang K, Li A, Song H, Zhang Z, Shi J, Liu J, Yang Y. | ACS Nano | 10.1021/acsnano.3c12687 | 2024 | | |
| Far-ultraviolet irradiation at 222 nm destroys and sterilizes the biofilms formed by periodontitis pathogens. | Nishikawa J, Fujii T, Fukuda S, Yoneda S, Tamura Y, Shimizu Y, Yanai A, Kobayashi Y, Harada K, Kawasaki K, Mishima K, Watanabe K, Mizukami Y, Yoshiyama H, Suehiro Y, Yamasaki T, Takami T. | J Microbiol Immunol Infect | 10.1016/j.jmii.2024.05.005 | 2024 | | |
| Evaluation of oral hygiene and gingival parameters in pediatric nephrotic syndrome within an interdisciplinary care model. | Piekoszewska-Zietek P, Panczyk-Tomaszewska M, Olczak-Kowalczyk D. | Sci Rep | 10.1038/s41598-025-06687-2 | 2025 | | |
| miR-135b Aggravates Fusobacterium nucleatum-Induced Cisplatin Resistance in Colorectal Cancer by Targeting KLF13. | Zeng W, Pan J, Ye G. | J Microbiol | 10.1007/s12275-023-00100-1 | 2024 | | |
| Microbiota and metabolite profiles of saliva, oral swab and cancer tissue from patients with oral squamous cell carcinoma (OSCC). | Wu K, Xu B, Zhou X, Guo H, Du G, Zhang C, Chen F, Chen X. | Infect Agent Cancer | 10.1186/s13027-025-00662-2 | 2025 | | |
| Clinical and Microbiological Study on Local Application of an Ozonated Olive Oil Gel in the Periodontal Pockets: A Randomized Double-Blind Trial | Grassi R, Ciccone F, De Falco D, Castaldi M, Agneta M, Nardi G, Petruzzi M. | J Clin Med | 2025 | | ||
| Pacemaker Infection and Parvimonas micra-Induced Prosthetic Aortic Valve Endocarditis With Periannular Abscess: A Case Report. | Boukobza M, Aubry P, Laissy JP. | Cureus | 10.7759/cureus.93749 | 2025 | | |
| Pathogenicity | Fusobacterium nucleatum and Its Impact on Colorectal Cancer Chemoresistance: A Meta-Analysis of In Vitro Co-Culture Infections. | Risoen KR, Shaw CA, Chien J, Weimer BC. | Cancers (Basel) | 10.3390/cancers17193247 | 2025 | |
| Amoxicillin-metronidazole disk for antimicrobial susceptibility testing of subgingival bacteria. | Jensen AB, Frandsen Lau E, Norskov-Lauritsen N. | J Oral Microbiol | 10.1080/20002297.2025.2508479 | 2025 | | |
| Characterisation of novel Fusobacterium nucleatum bacteriophages and their efficacy in disrupting pathogenic dual-species biofilms. | Kabwe M, Tucci J, Dashper S, Binte Mohamed Yakob Adil SS, Petrovski S. | J Oral Microbiol | 10.1080/20002297.2025.2584952 | 2025 | | |
| Comparative evaluation of light-emitting diode versus diode laser in photoactivated disinfection for endodontic retreatment: An in vivo study | Yeli M, Naik B, Kulkarni R, Bhat K, Moogi P, Tapashetti S, Karunakar P. | J Conserv Dent Endod | 2025 | | ||
| An integrated preventive and therapeutic magnetic nanoparticle loaded with rhamnolipid and vancomycin for combating subgingival biofilms. | Kang W, Zou T, Liang Y, Lei H, Zhang R, Kang J, Sun Z, Li X, Ge S, Zhang C. | Dent Mater | 10.1016/j.dental.2024.08.005 | 2024 | | |
| Pathogenicity | Oral Microbiome-Mediated Carcinogenesis in Oral Cavity Cancer: A Narrative Review | Semiz V, Aksoy R, Altun Z. | Cureus | | ||
| Antimicrobial Silk Fibroin Methacrylated Scaffolds for Regenerative Endodontics. | Narayanam R, Cardoso LM, Dos Reis-Prado AH, de Carvalho ABG, Anselmi C, Mahmoud AH, Fenno JC, Dal-Fabbro R, Bottino MC. | J Endod | 10.1016/j.joen.2024.08.004 | 2024 | | |
| Serum IgG titer findings for Fusobacterium nucleatum associated with clinical outcome following surgery in patients with esophageal squamous cell carcinoma. | Yoshikawa T, Nishi H, Emi M, Hamai Y, Ibuki Y, Kurokawa T, Hirohata R, Ohsawa M, Kitasaki N, Komatsuzawa H, Kawaguchi H, Okada M. | PLoS One | 10.1371/journal.pone.0336219 | 2025 | | |
| Antibacterial tellurium-containing polycarbonate drug carriers to eliminate intratumor bacteria for synergetic chemotherapy against colorectal cancer. | Hu J, Ran S, Huang Z, Liu Y, Hu H, Zhou Y, Ding X, Yin J, Zhang Y. | Acta Biomater | 10.1016/j.actbio.2024.06.042 | 2024 | | |
| Gut Microbiome Alterations in Colorectal Cancer: Mechanisms, Therapeutic Strategies, and Precision Oncology Perspectives. | Tudorache M, Treteanu AR, Gradisteanu Pircalabioru G, Lixandru-Petre IO, Bolocan A, Andronic O. | Cancers (Basel) | 10.3390/cancers17142294 | 2025 | | |
| Visualization of a Cell Wall Hydrolase Inhibitor in Fusobacterium nucleatum by Immunofluorescence Microscopy. | To K, Britton T, Ton-That H. | Methods Mol Biol | 10.1007/978-1-0716-3491-2_3 | 2024 | | |
| A New Method for Gene Deletion to Investigate Cell Wall Biogenesis in Fusobacterium nucleatum. | Bibek GC, Zhou P, Wu C. | Methods Mol Biol | 10.1007/978-1-0716-3491-2_6 | 2024 | | |
| Regulation of Gut Microbiota and Microbial Metabolome of Kefir Supernatant against Fusobacterium nucleatum and DSS-Coinduced Colitis. | Zeng X, Li J, Wang X, Liu L, Shen S, Li N, Wang Z, Yuan Y, Yue T. | J Agric Food Chem | 10.1021/acs.jafc.3c08050 | 2024 | | |
| Gut Microbiome-Mediated Genetic and Epigenetic Alterations in Colorectal Cancer: Population-Specific Insights. | Turcu S, Grama F, Gazouli M. | Biomedicines | 10.3390/biomedicines13092262 | 2025 | | |
| Fusobacterium nucleatum-Induced Empyema Masquerading as Lung Cancer: A Diagnostic Challenge. | Fadel AR, Ahmed YN. | Cureus | 10.7759/cureus.75003 | 2024 | | |
| Impact of Sociodemographic, Clinical, and Genetic Factors and Fusobacterium nucleatum on Premature Birth Outcomes in Women from Kazakhstan: A Case-Control Study. | Zhurabekova G, Balmagambetova A, Oralkhan Z, Sarsenova M, Toichiyeva G, Altynbay N, Malik A, Tastambek K, Berdalinova A. | Iran J Med Sci | 10.30476/ijms.2025.102996.3613 | 2025 | | |
| Fusobacterium nucleatum confirmed in gastric biopsies of patients without Helicobacter pylori. | Kamali N, Talebi Bezmin Abadi A, Rahimi F, Forootan M. | BMC Res Notes | 10.1186/s13104-025-07165-8 | 2025 | | |
| Associations between serum biomarkers and gut microbial imbalance in predicting chemotherapy response in colorectal cancer: A retrospective analysis. | Ling MZ, Wan Z, Hu B, Zhao MJ, Gong HS, Li G. | World J Gastrointest Oncol | 10.4251/wjgo.v17.i8.108870 | 2025 | | |
| Resveratrol is an inhibitory polyphenol of epithelial-mesenchymal transition induced by Fusobacterium nucleatum. | Min J, Mashimo C, Nambu T, Maruyama H, Takigawa H, Okinaga T. | Arch Oral Biol | 10.1016/j.archoralbio.2024.105897 | 2024 | | |
| Chemical Synthesis of the Trisaccharide Repeating Unit of the O-Antigen of Fusobacterium nucleatum ATCC 51191. | Sun W, Tian G, Ding M, Zou X, Hu J, Yin J. | Org Lett | 10.1021/acs.orglett.3c03981 | 2024 | | |
| The Oral-Gut-Systemic Axis: Emerging Insights into Periodontitis, Microbiota Dysbiosis, and Systemic Disease Interplay. | Harrandah AM. | Diagnostics (Basel) | 10.3390/diagnostics15212784 | 2025 | | |
| Leveraging immunoinformatics for developing a multi-epitope subunit vaccine against Helicobacter pylori and Fusobacterium nucleatum. | Tamanna T, Rahman MS. | J Biomol Struct Dyn | 10.1080/07391102.2023.2292295 | 2025 | | |
| Fusobacterium nucleatum exacerbates the progression of pulpitis by regulating the STING-dependent pathway. | Zhou L, Mao HQ, Li JQ, Chen Z, Zhang L. | FASEB J | 10.1096/fj.202301648r | 2024 | | |
| Ceramic conversion treated titanium implant abutments with gold for enhanced antimicrobial activity. | Aly YM, Zhang Z, Ali N, Milward MR, Poologasundarampillai G, Dong H, Kuehne SA, Camilleri J. | Dent Mater | 10.1016/j.dental.2024.05.029 | 2024 | | |
| Role of Anti-coagulation in Lemierre's Syndrome With Empyema. | Paing L, Shahzad K, Hlaing T, Htwe T, Siddiqui S. | Cureus | 10.7759/cureus.92256 | 2025 | | |
| Fisetin Inhibits Periodontal Pathogen-Induced EMT in Oral Squamous Cell Carcinoma via the Wnt/beta-Catenin Pathway. | Zhang R, Takigawa H, Maruyama H, Nambu T, Mashimo C, Okinaga T. | Nutrients | 10.3390/nu17223522 | 2025 | | |
| Emerging strategies for combating Fusobacterium nucleatum in colorectal cancer treatment: Systematic review, improvements and future challenges. | Liu H, Yu Y, Dong A, Elsabahy M, Yang YW, Gao H. | Exploration (Beijing) | 10.1002/exp.20230092 | 2024 | | |
| Pathogenicity | Elevated levels of circulating microbial-associated uremic toxins are associated with metastatic duodenopancreatic neuroendocrine tumors in patients with Multiple Endocrine Neoplasia Type 1. | Ballaro R, Wasylishen AR, Pieterman CRC, Olsen C, Irajizad E, Wu R, Katayama H, Liu H, Cai Y, Leon-Letelier RA, Dennison JB, Waguespack S, Do KA, Agarwal SK, Walter M, Welch J, Weinstein L, Blau JE, Jha S, Nilubol N, Vriens MR, van Leeuwaarde RS, van Treijen MJC, Valk GD, Perrier ND, Hanash SM, Fahrmann JF. | Cancer Lett | 10.1016/j.canlet.2025.217537 | 2025 | |
| Mixed oral biofilms are controlled by the interspecies interactions of Fusobacterium nucleatum. | Valadbeigi H, Khoshnood S, Negahdari B, Maleki A, Mohammadinejat M, Haddadi MH. | Oral Dis | 10.1111/odi.14822 | 2024 | | |
| Pyogenic liver abscess and sepsis caused by mixed anaerobic bacteria in an immunocompetent adult: a case report. | Fan Z, Mei M, Chen C. | Front Med (Lausanne) | 10.3389/fmed.2025.1486256 | 2025 | | |
| Fabrication of hyaluronic acid-inulin coated Enterococcus faecium for colon-targeted delivery to fight Fusobacterium nucleatum. | Zhu P, Meng L, Shu Y, Xu Y, Liu W, Bi Y, Xu J, Meng L, Li Y. | Carbohydr Polym | 10.1016/j.carbpol.2024.121797 | 2024 | | |
| Fusobacterium nucleatum induces oxaliplatin resistance by inhibiting ferroptosis through E-cadherin/beta-catenin/GPX4 axis in colorectal cancer. | Li B, Wei Z, Wang Z, Xu F, Yang J, Lin B, Chen Y, Wenren H, Wu L, Guo X, Liu Y, Wei Y. | Free Radic Biol Med | 10.1016/j.freeradbiomed.2024.04.226 | 2024 | | |
| First reported Tannerella forsythia infection in a patient with extensive bronchiectasis: a case report. | Fu C, Sun Y, Chen C. | Front Med (Lausanne) | 10.3389/fmed.2025.1571506 | 2025 | | |
| Engineering lauric acid-based nanodrug delivery systems for restoring chemosensitivity and improving biocompatibility of 5-FU and OxPt against Fn-associated colorectal tumor. | Su M, Wen X, Yu Y, Li N, Li X, Qu X, Elsabahy M, Gao H. | J Mater Chem B | 10.1039/d4tb00103f | 2024 | | |
| [Banxia Xiexin Decoction inhibiting colitis-associated colorectal cancer infected with Fusobacterium nucleatum by regulating Wnt/beta-catenin pathway]. | Jiang YF, Huang YQ, Hu YE, Yang Y, Zheng C, You FM, Zhao ZY. | Zhongguo Zhong Yao Za Zhi | 10.19540/j.cnki.cjcmm.20231114.701 | 2024 | | |
| Systematic Review: The Relationship Between the Faecal Microbiome and Colorectal Neoplasia in Shotgun Metagenomic Studies. | Manning S, Hackney E, Dunneram Y, Hull MA, Mitra S, Stewart CJ, Louca P, Meader N, Sharp L, Rees C. | Aliment Pharmacol Ther | 10.1111/apt.70252 | 2025 | | |
| Enzymology | Structural and Functional Analyses of the Flavoprotein Disulfide Reductase FN0820 of Fusobacterium nucleatum. | Shin H, Baek Y, Lee D, Xu Y, Kwon Y, Jo I, Ha NC. | J Microbiol | 10.1007/s12275-023-00095-9 | 2023 | |
| Efficacy of toothpaste containing Brazilian green propolis extracts with an optimal kaempferide/betuletol ratio for improving oral microbiota: A randomized, controlled, paired crossover study. | Amano S, Matsumoto M, Morimoto M, Kawamoto H, Takeshita F, Yasui T, Sakagami H. | J Ethnopharmacol | 10.1016/j.jep.2024.118762 | 2025 | | |
| Banxia Xiexin Decoction delays colitis-to-cancer transition by inhibiting E-cadherin/beta-catenin pathway via Fusobacterium nucleatum FadA. | Jiang Y, Huang Y, Hu Y, Yang Y, You F, Hu Q, Li X, Zhao Z. | J Ethnopharmacol | 10.1016/j.jep.2024.117932 | 2024 | | |
| Production and characterization of the lipopeptide with anti-adhesion for oral biofilm on the surface of titanium for dental implants. | Carvalho FS, Tarabal VS, Livio DF, Cruz LF, Monteiro APF, Parreira AG, Guimaraes PPG, Scheuerman K, Chagas RCR, da Silva JA, Goncalves DB, Granjeiro JM, Sinisterra RD, Segura MEC, Granjeiro PA. | Arch Microbiol | 10.1007/s00203-024-04078-1 | 2024 | | |
| Host-Gut Microbiota Metabolic Interactions and Their Role in Precision Diagnosis and Treatment of Gastrointestinal Cancers. | Cao C, Yue S, Lu A, Liang C. | Pharmacol Res | 10.1016/j.phrs.2024.107321 | 2024 | | |
| Glycolanguage of the oral microbiota. | Hager-Mair FF, Bloch S, Schaffer C. | Mol Oral Microbiol | 10.1111/omi.12456 | 2024 | | |
| Sulfated Chitosan-Modified CuS Nanocluster: A Versatile Nanoformulation for Simultaneous Antibacterial and Bone Regenerative Therapy in Periodontitis. | Chen X, Huang N, Wang D, Zhang M, Deng X, Guo F, Yi B, Yuan C, Zhou Q. | ACS Nano | 10.1021/acsnano.4c00137 | 2024 | | |
| Association of Fusobacterium nucleatum infection with the clinicopathological characteristics in colorectal cancer patients. | Pang SW, Armon S, Chook JB, Chew J, Peh KB, Lim WW, Peh SC, Teow SY. | Mol Biol Rep | 10.1007/s11033-023-09150-5 | 2024 | | |
| Fusobacterium nucleatum dysregulates inflammatory cytokines and NLRP3 inflammasomes in oral cells. | Sun J, Feng S, Ding T, Wang T, Du L, Kang W, Ge S. | Oral Dis | 10.1111/odi.14899 | 2024 | | |
| Discovery of New Fusobacterium nucleatum Inhibitors to Attenuate Migratory Capability of Colon Cancer Cells by the Drug Repositioning Strategy. | Pan Z, Zhou C, Bai X, Wang F, Hong J, Fang JY, Huang Y, Sheng C. | J Med Chem | 10.1021/acs.jmedchem.3c00281 | 2023 | | |
| Potential and application of Fusobacterium nucleatum in the diagnosis and treatment of colorectal cancer. | He X, Zhao Q, Zhang J, Shi J, Wan N, Tang B, Tian B, Li P. | Front Microbiol | 10.3389/fmicb.2025.1652702 | 2025 | | |
| Revisiting berberine for the prevention and treatment of Fusobacterium nucleatum-induced colorectal cancer from a dynamic perspective. | Bi D, Yang X, Yong J, Huang J, Liu Z, Gong R. | Front Microbiol | 10.3389/fmicb.2025.1637272 | 2025 | | |
| Role of the Microbiome in the Diagnosis and Management of Gastroesophageal Cancers. | Mascaretti F, Haider S, Amoroso C, Caprioli F, Ramai D, Ghidini M. | J Gastrointest Cancer | 10.1007/s12029-024-01021-x | 2024 | | |
| Genetics | Gut-Microbiome Signatures Predicting Response to Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer: A Systematic Review. | Domilescu I, Miutescu B, Horhat FG, Popescu A, Nica C, Ghiuchici AM, Gadour E, Sirbu I, Hutanu D. | Metabolites | 10.3390/metabo15060412 | 2025 | |
| Associations between periodontitis and serum anti-malondialdehyde-acetaldehyde antibody concentrations in rheumatoid arthritis: A case-control study. | Lee JA, Mikuls TR, Sayles HR, Thiele GM, Duryee MJ, Payne JB. | J Periodontol | 10.1002/jper.23-0604 | 2024 | | |
| Effects of Lactiplantibacillus plantarum CCFM1214 and Ligilactobacillus salivarius CCFM1215 on halitosis: a double-blind, randomized controlled trial. | Ding L, Wang Y, Jiang Z, Tang X, Mao B, Zhao J, Chen W, Zhang Q, Cui S. | Food Funct | 10.1039/d4fo02280g | 2024 | | |
| Structural insight into the role of thiolase from Fusobacterium nucleatum. | He S, Bai X, Xu Y. | Biochem Biophys Res Commun | 10.1016/j.bbrc.2023.149151 | 2023 | | |
| Phylogeny | Pleural space infection microbiology as assessed using a clinical sequencing-based assay: Fusobacterium nucleatum group, Streptococcus intermedius, and other oral normal microbiota are the most common bacteria identified in community-acquired pleural space infections. | Alvarez Otero J, Mandrekar J, Wolf MJ, Starkey JC, Carmona EM, Dyrhovden R, Kommedal O, Patel R. | J Clin Microbiol | 10.1128/jcm.00694-24 | 2024 | |
| Autoinducer-2 produced by oral microbial flora and alveolar bone loss in periodontitis. | Li C, Zhou H, Gou H, Fan Z, Zhang Y, Tang P, Huang J, Xu Y, Li L. | J Periodontal Res | 10.1111/jre.13247 | 2024 | | |
| Exploring odontogenic brain abscesses: a comprehensive review. | Wu X, Qin N, Peng X, Wang L. | Acta Neurol Belg | 10.1007/s13760-024-02569-y | 2024 | | |
| [Advances on the treatment of Fusobacterium nucleatum-promoted colorectal cancers using nanomaterials]. | Wang H, Hou X, Liu J, Yang C. | Sheng Wu Gong Cheng Xue Bao | 10.13345/j.cjb.220811 | 2023 | | |
| Does a link exist between oral microbiota and oral squamous cell carcinoma? A review of current insights. | Santacroce L, Jirillo E, Bottalico L, Topi S, Passarelli PC, Mancini A, D'Addona A, Garcia Godoy F, Folliero V, Colella M. | J Oral Microbiol | 10.1080/20002297.2025.2569934 | 2025 | | |
| Enzymology | Antibacterial activity of mulberry extracts and purified fractions against oral pathogenic bacteria. | Shirai T, Satoh Y, Ishihara K. | J Oral Biosci | 10.1016/j.job.2023.12.009 | 2024 | |
| The presence and relative abundance of salivary Fusobacterium nucleatum are not associated with colorectal cancer: a systematic review and meta-analysis. | Gutmacher E, Sarai BZ, Martinekova P, Kiss-Dala S, Agocs G, Hegyi P, Brody A, Zsembery A. | Sci Rep | 10.1038/s41598-025-07465-w | 2025 | | |
| Phylogeny | Oropharyngeal microbiome dysbiosis in esophageal squamous cell carcinoma: taxonomic shifts, metabolic reprogramming, and geographic disparities in a high-incidence cohort. | Liu Y, Wu E, Cheng F, Zhang M, Rou Q, Nuertai Z, Xu M, Xu S, Li M, Zhang L, Nasiroula A. | PeerJ | 10.7717/peerj.20009 | 2025 | |
| Role of curcumin in oral infection and inflammation. | Shunmugavelu K, Bhaskar G. | GMS Hyg Infect Control | 10.3205/dgkh000575 | 2025 | | |
| Fusobacterium nucleatum Is Associated with Tumor Characteristics, Immune Microenvironment, and Survival in Appendiceal Cancer. | Sherry C, Dadgar N, Park H, Knotts C, Grayhack E, Blodgett R, Xiao K, Omstead AN, Donnenberg AD, Bartlett DL, Donnenberg V, Goel A, Zaidi AH, Wagner PL. | Microorganisms | 10.3390/microorganisms13071644 | 2025 | | |
| Periodontal and microbiological evaluation in cleft lip/palate patients undergoing orthodontic treatment: An in vitro study. | Yadav S, Yadav K, Madhad V, Kumar A, Saha A, Agrawal N. | Bioinformation | 10.6026/973206300211286 | 2025 | | |
| Fusobacterium nucleatum is enriched in invasive biofilms in colorectal cancer. | Queen J, Cing Z, Minsky H, Nandi A, Southward T, Ferri J, McMann M, Iyadorai T, Vadivelu J, Roslani A, Loke MF, Wanyiri J, White JR, Drewes JL, Sears CL. | NPJ Biofilms Microbiomes | 10.1038/s41522-025-00717-7 | 2025 | | |
| Advancements in understanding tumor-resident bacteria and their application in cancer therapy. | Luo YC, Huang XT, Wang R, Lin YJ, Sun JX, Li KF, Wang DY, Yan Y, Qiao YK. | Mil Med Res | 10.1186/s40779-025-00623-1 | 2025 | | |
| Effect of Mouth Rinsing and Antiseptic Solutions on Periodontitis Bacteria in an In Vitro Oral Human Biofilm Model. | Strenge JT, Smeets R, Geffken M, Beikler T, Stuermer EK. | Dent J (Basel) | 10.3390/dj13070324 | 2025 | | |
| Transcriptome | Single-cell and bulk transcriptomics reveal Fusobacterium nucleatum promotes colorectal cancer metastasis by upregulating LAMC2 in in vitro and in vivo models. | Ran S, Ye J, Wang H, Liu F, Ou S, Chen Z, Song Y, Liu SL, Huang R. | Sci Rep | 10.1038/s41598-025-26249-w | 2025 | |
| Fusobacterium nucleatum putatively affects the alveoli by disrupting the alveolar epithelial cell tight junction, enlarging the alveolar space, and increasing paracellular permeability. | Karahashi Y, Cueno ME, Kamio N, Takahashi Y, Takeshita I, Soda K, Maruoka S, Gon Y, Sato S, Imai K. | Biochem Biophys Res Commun | 10.1016/j.bbrc.2023.10.026 | 2023 | | |
| From the Pancreas to the Groin: A Scrotal Abscess Following Pancreatic Fully Covered Self-Expandable Metal Stent Placement. | Alp J, Mallery JS, Trikudanathan G, Freeman ML. | Cureus | 10.7759/cureus.87075 | 2025 | | |
| Unraveling the Role of Fusobacterium nucleatum in Colorectal Cancer: Molecular Mechanisms and Pathogenic Insights. | Galasso L, Termite F, Mignini I, Esposto G, Borriello R, Vitale F, Nicoletti A, Paratore M, Ainora ME, Gasbarrini A, Zocco MA. | Cancers (Basel) | 10.3390/cancers17030368 | 2025 | | |
| Fusobacterium nucleatum Bacteremia Presenting as Isolated Superior Mesenteric Vein Thrombophlebitis. | Agarwal A, Yetiskul E, Patel R, Qaqish F, Qandil H, Mobarakai N. | Case Rep Infect Dis | 10.1155/2024/5349136 | 2024 | | |
| Chitosan from sea urchin (Diadema setosum) spines for orthodontic miniscrews: Antibacterial effects against key oral pathogens. | Mansjur KQ, Erwansyah E, Pawinru AS, Nasir M, Djais AI, Sumule VC, Attaya NS, Arinawaty DY, Hutami IR, Permana AD. | J Oral Biol Craniofac Res | 10.1016/j.jobcr.2025.02.014 | 2025 | | |
| Remotely Controllable Supramolecular Nanomedicine for Drug-Resistant Colorectal Cancer Therapy Caused by Fusobacterium nucleatum. | Yan X, Xin Y, Yu Y, Li X, Li B, Elsabahy M, Zhang J, Ma F, Gao H. | Small Methods | 10.1002/smtd.202301309 | 2024 | | |
| Microbial Analysis in Chronic Rhinosinusitis Patients with Chronic Kidney Disease and End-Stage Renal Disease. | Lo SW, Ding MC, Tsai YT, Tsai MS, Liu CY, Hsu CM, Yang YH, Chang GH. | Laryngoscope | 10.1002/lary.31389 | 2024 | | |
| Preventive and Therapeutic Potential of Streptococcus cristatus CA119 in Experimental Periodontitis in Rats. | Zhao D, Li MH, Pan T, Guo J, Li J, Shi C, Wang N, Huang H, Wang C, Yang G. | Probiotics Antimicrob Proteins | 10.1007/s12602-024-10254-y | 2025 | | |
| Size-tunable nanogels for cascaded release of metronidazole and chemotherapeutic agents to combat Fusobacterium nucleatum-infected colorectal cancer. | Xie S, Wei L, Liu Y, Meng J, Cao W, Qiu B, Li X. | J Control Release | 10.1016/j.jconrel.2023.11.018 | 2024 | | |
| Effects of nanomodified titanium surfaces considering bacterial colonization and viability of osteoblasts and fibroblasts. | Astasov-Frauenhoffer M, Marot L, Sanchez F, Steiner R, Lohberger B, Bornstein MM, Wagner RS, Kuhl S, Mukaddam K. | J Biomed Mater Res A | 10.1002/jbm.a.37768 | 2024 | | |
| Proteomics of Periodontitis-Associated Bacteria and Its Link to Oral Squamous Cell Carcinoma: A Contemporaneous Review. | Yeong S, Cheah C, Tilakaratne A, Tilakaratne WM. | Int Dent J | 10.1016/j.identj.2025.103980 | 2025 | | |
| Stroke Caused by Vasculitis Induced by Periodontitis-Associated Oral Bacteria after Wisdom Teeth Extraction. | Kiramira D, Uphaus T, Othman A, Heermann R, Deschner J, Muller-Heupt LK. | Brain Sci | 10.3390/brainsci14060550 | 2024 | | |
| The EUCAST Disk Diffusion Method for Antimicrobial Susceptibility Testing of Oral Anaerobes. | Jensen AB, Lau EF, Greve T, Norskov-Lauritsen N. | APMIS | 10.1111/apm.70002 | 2025 | | |
| Histopathological study of the localization/distribution of Fusobacterium nucleatum in esophageal cancer. | Sasaki-Higashimoto I, Fujishima F, Ishida H, Taniyama Y, Ozawa Y, Nakamura T, Nakaya N, Sato C, Okamoto H, Tsunokake J, Kunimitsu A, Mozumi T, Kamei T, Suzuki T. | Pathol Int | 10.1111/pin.13505 | 2025 | | |
| Effects of metronidazole on colorectal cancer occurrence and colorectal cancer liver metastases by regulating Fusobacterium nucleatum in mice. | Wang M, Li Y, Yang X, Liu Z, Wang K, Gong D, Li J. | Immun Inflamm Dis | 10.1002/iid3.1067 | 2023 | | |
| Impact of Periodontitis on the Leakage of Oral Bacteria to the Gut. | Buetas E, Jordan-Lopez M, Lopez-Roldan A, Mira A, Carda-Dieguez M. | J Dent Res | 10.1177/00220345231221709 | 2024 | | |
| Tomato-fruit-derived extracellular vesicles inhibit Fusobacterium nucleatum via lipid-mediated mechanism. | Lee BH, Wu SC, Chien HY, Shen TL, Hsu WH. | Food Funct | 10.1039/d3fo01608k | 2023 | | |
| Gallium-doped zirconia coatings modulate microbiological outcomes in dental implant surfaces. | D'Agostino A, Misiti G, Scalia AC, Pavarini M, Fiorati A, Cochis A, Rimondini L, Borrini VF, Manfredi M, Andena L, De Nardo L, Chiesa R. | J Biomed Mater Res A | 10.1002/jbm.a.37727 | 2024 | | |
| Gut Microbiota as a Key Modulator of Chronic Disease: Implications for Diabetes, Autoimmunity, and Cancer. | Inayat N, Zahir A, Hashmat AJ, Khan A, Ahmad A, Sikander M, Zakir S, Ahmad S, Awan SK, Raza SS, Varrassi G. | Cureus | 10.7759/cureus.84687 | 2025 | | |
| Microbiota of Peri-Implant Healthy Tissues, Peri-Implant Mucositis, and Peri-Implantitis: A Comprehensive Review. | Di Spirito F, Giordano F, Di Palo MP, D'Ambrosio F, Scognamiglio B, Sangiovanni G, Caggiano M, Gasparro R. | Microorganisms | 10.3390/microorganisms12061137 | 2024 | | |
| Global prevalence of Fusobacterium nucleatum and Bacteroides fragilis in patients with colorectal cancer: an overview of case reports/case series and meta-analysis of prevalence studies. | Sameni F, Elkhichi PA, Dadashi A, Sadeghi M, Goudarzi M, Eshkalak MP, Dadashi M. | BMC Gastroenterol | 10.1186/s12876-025-03664-x | 2025 | | |
| Delivery of short chain fatty acid butyrate to overcome Fusobacterium nucleatum-induced chemoresistance. | Chen L, Zhao R, Kang Z, Cao Z, Liu N, Shen J, Wang C, Pan F, Zhou X, Liu Z, Yang Y, Chen Q. | J Control Release | 10.1016/j.jconrel.2023.09.028 | 2023 | | |
| SmartGel OV: A Natural Origanum vulgare-Based Adjunct for Periodontitis with Clinical and Microbiological Evaluation | Radu C, Radu C, Zaha D. | Medicina (Kaunas) | 2025 | | ||
| A Rare Case of Pyopneumothorax Due to Streptococcus intermedius in a Previously Healthy Woman. | Zohouri M, Zahid A, Silvestre A, Rabbani K, Dargan K, Thomas J. | Case Rep Pulmonol | 10.1155/crpu/1665286 | 2025 | | |
| Effect of Nitrogen Doping on the Photocatalytic Properties and Antibiofilm Efficacy of Reduced TiO2 Nanoparticles. | Tsai YH, Milbrandt NB, Prado RC, Ponce NB, Alam MM, Qiu SR, Yu X, Burda C, Kim TKJ, Samia ACS. | ACS Appl Bio Mater | 10.1021/acsabm.4c00459 | 2024 | | |
| Tinidazole mouth rinse for the treatment of oral lichen planus: an observational pilot study. | Shao R, Wang Z, Yang C, Pan L, Chen X, Du G. | BMC Oral Health | 10.1186/s12903-024-04881-8 | 2024 | | |
| Amphiphilic polymeric nanodrug integrated with superparamagnetic iron oxide nanoparticles for synergistic antibacterial and antitumor therapy of colorectal cancer. | Li X, Niu J, Deng L, Yu Y, Zhang L, Chen Q, Zhao J, Wang B, Gao H. | Acta Biomater | 10.1016/j.actbio.2023.11.019 | 2024 | | |
| Development of a loop-mediated isothermal amplification assay for detecting Porphyromonas endodontalis. | Whitaker EJ, Shah LN, Miloradovic IR, Yesilsoy CJ, Badve SA. | J Conserv Dent Endod | 10.4103/jcde.jcde_859_24 | 2025 | | |
| Phenotype | Characteristics of gut microbiota in high-methylated colorectal cancer. | Saito T, Karasawa H, Ouchi K, Ono T, Kajiwara T, Kohyama A, Ikeda-Ohtsubo W, Fukuda S, Fujishima F, Ozawa Y, Suzuki H, Watanabe K, Ishioka C, Kamei T, Ohnuma S, Abe T, Unno M. | Int J Clin Oncol | 10.1007/s10147-025-02812-3 | 2025 | |
| Advances in the study of oral microbiota in association with T2DM: a systematic review. | Huang M, Zhang X, Di L, Yi Z. | Front Cell Infect Microbiol | 10.3389/fcimb.2025.1629304 | 2025 | | |
| The Influence of Local Antibiotic Therapy on the Microbiological, Clinical, and Radiological Outcomes Following Minimally Invasive Periodontal Surgery in the Treatment of Intrabony Defects-A Randomized Clinical Trial. | Skurska A, Baczewska A, Milewski R, Majewski P, Charkiewicz R. | Antibiotics (Basel) | 10.3390/antibiotics14090850 | 2025 | | |
| Phylogeny | Peridontopathogenic key species in correlation to the current classification system. | Sigusch B, Kranz S, Heyder M, Weber A, Gullmar A, Mahmudova N, Reise M. | Clin Oral Investig | 10.1007/s00784-025-06413-2 | 2025 | |
| Metastasis and the Microbiome: The Impact of Bacteria in Disseminated Colorectal Cancer. | Ayabe RI, White MG. | Front Biosci (Landmark Ed) | 10.31083/j.fbl2904152 | 2024 | | |
| Periodontitis increases the risk of gastrointestinal dysfunction: an update on the plausible pathogenic molecular mechanisms. | Mukherjee S, Chopra A, Karmakar S, Bhat SG. | Crit Rev Microbiol | 10.1080/1040841x.2024.2339260 | 2025 | | |
| Periodontal Microbial Profiles Across Periodontal Conditions in Pediatric Subjects: A Narrative Review | Di Spirito F, Di Palo M, De Benedetto G, Piedepalumbo F, Galdi M, Cannata D, Cafa N, Contaldo M. | Microorganisms | 2025 | | ||
| Enzymology | Direct coupling of lactate oxidation with butyryl-CoA formation via a canonical electron transfer flavoprotein in Fusobacterium nucleatum. | Do LTM, Godin R, Wolthers KR. | J Biol Chem | 10.1016/j.jbc.2025.110796 | 2025 | |
| Comparison of light gradient boosting and logistic regression for interactomic hub genes in Porphyromonas gingivalis and Fusobacterium nucleatum-induced periodontitis with Alzheimer's disease. | Yadalam PK, Chatterjee S, Natarajan PM, Ardila CM. | Front Oral Health | 10.3389/froh.2025.1463458 | 2025 | | |
| Subgingival 0.75% boric acid vs 1% povidone-iodine adjunctive to subgingival instrumentation in stage II and III periodontitis-A double-blind randomized clinical trial. | Pham TAV, Nguyen MD. | Int J Dent Hyg | 10.1111/idh.12819 | 2025 | | |
| Harnessing gut microbiota for colorectal cancer therapy: from clinical insights to therapeutic innovations. | Chen C, Su Q, Zi M, Hua X, Zhang Z. | NPJ Biofilms Microbiomes | 10.1038/s41522-025-00818-3 | 2025 | | |
| Comparative Evaluation of the Antimicrobial Efficacy of Anethum Graveolens Gel with Chlorhexidine Gel against Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis and Fusobacterium nucleatum- an in vitro study. | Patel RS, Metgud RM, Dodamani S, Nadaf R, Patil A. | Arch Razi Inst | 10.32592/ari.2025.80.1.225 | 2025 | | |
| A Fluorogenic DNAzyme for A Thermally Stable Protein Biomarker from Fusobacterium nucleatum, a Human Bacterial Pathogen. | Feng Q, Zakaria S, Morrison D, Tram K, Gu J, Salena BJ, Li Y. | Angew Chem Int Ed Engl | 10.1002/anie.202306272 | 2023 | | |
| Salivary Molecular Testing for Periodontal Pathogen Monitoring: Clinical Performance of Flexible RT-PCR Platforms in Preventive Care Settings. | D'Urso F, Paladini F, Pollini M, Broccolo F. | Diagnostics (Basel) | 10.3390/diagnostics15192548 | 2025 | | |
| Functional and taxonomic dysbiosis of the supragingival plaque metagenome in Behçet's disease. | Sapthanakorn T, Choopong P, Sermsripong W, Boriboonhirunsarn C, Khamwachirapitak C, Krasaesin A, Sutthiboonyaphan P, Siripaiboonpong N, Mahanonda R, Wiriyakijja P, Pelekos G, Porntaveetus T, Srithanyarat SS. | J Oral Microbiol | 10.1080/20002297.2025.2552165 | 2025 | | |
| Fusobacterium nucleatum infection activates the noncanonical inflammasome and exacerbates inflammatory response in DSS-induced colitis. | Boonyaleka K, Okano T, Iida T, Leewananthawet A, Sasai M, Yamamoto M, Ashida H, Suzuki T. | Eur J Immunol | 10.1002/eji.202350455 | 2023 | | |
| The role of gut microbiome in colorectal cancer development: a comprehensive analysis based on metabolomics and immunomodulatory mechanisms. | Xu Y, Wen B, Liu S. | Front Oncol | 10.3389/fonc.2025.1629495 | 2025 | | |
| Tooth Eruption and Microbial Correlation in Pediatric Appendicitis: An Exploratory Case-Control Study. | Elger W, Blod C, Schulin S, Hirsch C, Lacher M, Mayer S. | J Clin Med | 10.3390/jcm14207372 | 2025 | | |
| Application of on-demand aqueous chlorine dioxide solution for non-surgical root canal treatment. | Shimaoka T, Maezono H, Ono S, Asahi Y, Kawanishi Y, Klanliang K, Takahashi Y, Hayashi M. | Sci Rep | 10.1038/s41598-025-20131-5 | 2025 | | |
| Differences in diversity and composition of mucosa-associated colonic microbiota in colorectal cancer and non-colorectal cancer in Indonesia. | Darnindro N, Abdullah M, Sukartini N, Rumende CM, Pitarini A, Nursyirwan SA, Fauzi A, Makmun D, Nelwan EJ, Shatri H, Rinaldi I, Tanadi C. | World J Gastroenterol | 10.3748/wjg.v31.i7.100051 | 2025 | | |
| Pyopericardium with cardiac tamponade caused by pyogenic liver abscess: a case report. | Steffen C, Sagmuller J, Schoneburg D, Goncz E, Mockel M, Ott S, Ungur AL, O 'Brien B. | J Med Case Rep | 10.1186/s13256-024-05014-z | 2025 | | |
| Microbiome influence in gastric cancer progression and therapeutic strategies. | Bautista J, Maldonado-Noboa I, Maldonado-Guerrero D, Reinoso-Quinga L, Lopez-Cortes A. | Front Med (Lausanne) | 10.3389/fmed.2025.1681824 | 2025 | | |
| Cross-cohort analysis identifies shared gut microbial signatures and validates microbial risk scores for colorectal cancer. | Zhang Y, Luo J, Chen K, Li N, Luo C, Di S, Qin J, Zhang F, Chen H, Dai M. | J Transl Med | 10.1186/s12967-025-06676-z | 2025 | | |
| Genetics | Limitations of MALDI-TOF MS in identifying anaerobic bacteremia: challenges in polymicrobial infections and the role of whole-genome sequencing. | Hosoda T, Suzuki M, Matsuno T, Matsui K, Ohyama K, Doi Y. | Microbiol Spectr | 10.1128/spectrum.01014-25 | 2025 | |
| Causal Association Between Oral Microbiota and Major Salivary Gland Cancer: A Bidirectional Two-Sample Mendelian Randomization Study. | Ip Y, Chu H. | Oral Health Prev Dent | 10.3290/j.ohpd.c_2333 | 2025 | | |
| Fusobacterium nucleatum promotes metastasis of breast cancer via the miR-21-3p/FOXO3 axis. | Huang Y, Guo Z, Zeng Z, Shang C, Zhang Y, Ran Z, Luo G, Shen S, Liu Y, Zhou P, Ma P, Zhang Y, Lin H, Lu Y, Liu D. | Front Oncol | 10.3389/fonc.2025.1530269 | 2025 | | |
| Antibacterial Fusobacterium nucleatum-Mimicking Nanomedicine to Selectively Eliminate Tumor-Colonized Bacteria and Enhance Immunotherapy Against Colorectal Cancer. | Chen L, Zhao R, Shen J, Liu N, Zheng Z, Miao Y, Zhu J, Zhang L, Wang Y, Fang H, Zhou J, Li M, Yang Y, Liu Z, Chen Q. | Adv Mater | 10.1002/adma.202306281 | 2023 | | |
| Periodontitis-associated Fusobacterium nucleatum promotes ulcerative colitis by ferroptosis-mediated gut barrier disruption. | Zhang X, Cheng S, Chen S, Wang Q, Zhou J, Wang H, Cheng L, Zhao L. | NPJ Biofilms Microbiomes | 10.1038/s41522-025-00763-1 | 2025 | | |
| Effect of a Probiotic Combination on Clinical and Microbiological Oral Parameters in Head and Neck Cancer Patients: A Randomised Clinical Trial | Pereira Riveros T, Jane Salas E, Lozano Borbalas A, Aguilera F, Vinuesa Aumedes T. | Cancers (Basel) | 2025 | | ||
| Quantitative real-time PCR analysis of gut microbiota in rheumatoid arthritis patients compared to healthy controls. | Masroor A, Gholipour A, Shahini Shams Abadi M, Mousavi M, Hadi Alijanvand M, Zamanzad B. | AMB Express | 10.1186/s13568-024-01785-2 | 2024 | | |
| Fusobacterium nucleatum and Gastric Cancer: An Emerging Connection | Sorino J, Della Mura M, Ingravallo G, Cazzato G, Pizzimenti C, Zuccala V, Pepe L, Germana E, Martini M, Ieni A, Fiorentino V. | Int J Mol Sci | 2025 | | ||
| Pathogenicity | The power of microbes: the key role of gut microbiota in the initiation and progression of colorectal cancer. | Han B, Zhang Y, Feng X, Yang J, Wang B, Fang J, Wang Z, Zhu J, Niu G, Guo Y. | Front Oncol | 10.3389/fonc.2025.1563886 | 2025 | |
| Association Between Oral Microbiota Dysbiosis and the Risk of Dementia: A Systematic Review. | Chaple-Gil AM, Santiesteban-Velazquez M, Urbizo Velez JJ. | Dent J (Basel) | 10.3390/dj13060227 | 2025 | | |
| Phylogeny | Nanopore full length 16S rRNA gene sequencing increases species resolution in bacterial biomarker discovery. | Aja-Macaya P, Conde-Perez K, Trigo-Tasende N, Buetas E, Nasser-Ali M, Nion P, Rumbo-Feal S, Ladra S, Bou G, Mira A, Vallejo JA, Poza M. | Sci Rep | 10.1038/s41598-025-10999-8 | 2025 | |
| Management of patient with Fusobacterim nucletum related pleural empyema: intrapleural antibiotic therapy can be considered for salvage therapy. | Wang J, Li J, Sun Z, Zhang S, Ma L, Liu X, Yang X, Ai J, YuanSong, Sun L, Li X, He T, Xiao Y, Gao H, Yuan F. | BMC Infect Dis | 10.1186/s12879-024-09582-9 | 2024 | | |
| Whole-Bacterium SELEX Aptamer Selection of Fusobacterium nucleatum and Application to Colorectal Cancer Noninvasive Screening in Human Feces. | Wang N, Fan T, Chen Y, Chen H, Qin Y, Jiang Y. | Anal Chem | 10.1021/acs.analchem.3c00565 | 2023 | | |
| Type IV pili facilitated natural competence in Fusobacterium nucleatum. | Sanders BE, Umana A, Nguyen TTD, Williams KJ, Yoo CC, Casasanta MA, Wozniak B, Slade DJ. | Anaerobe | 10.1016/j.anaerobe.2023.102760 | 2023 | | |
| Antineoplastic therapy in childhood cancer patients presents a negative impact in the periodontal tissues: a cohort study. | Longo BC, Rohling IB, Silva PLMOE, de Morais MEF, Paz HES, Casarin RCV, Nishiyama SAB, de Souza MDB, Silva CO. | Clin Oral Investig | 10.1007/s00784-023-05270-1 | 2023 | | |
| Antimicrobial Efficacy of Aloe Vera, Chlorhexidine, Hyaluronic Acid, and Diode Laser Against Periodontopathogenic Bacteria: A Mixed-Methods Study. | Zadode A, Shiggaon L, Ghagre S, Mane VM, Chintale SB, Awaghad SS, Patil A. | Cureus | 10.7759/cureus.88283 | 2025 | | |
| Relationship between periodontal diseases and non-specific inflammatory bowel diseases - an overview. Part I. | Gozdziewska M, Lyszczarz A, Kaczoruk M, Kolarzyk E. | Ann Agric Environ Med | 10.26444/aaem/185764 | 2024 | | |
| Optimizing Red Light-Based Photodynamic Therapy for Effective Bactericidal Action Against Fusobacterium nucleatum Subspecies. | Li J, Nambu T, Wang C, Takigawa H, Maruyama H, Mashimo C, Okinaga T. | Pathogens | 10.3390/pathogens13111016 | 2024 | | |
| Cholecystopleural fistula as a cause of recurrent infected biliothorax. | Saito Z, Yasuda Y, Maeda D, Ichikado K. | Respir Med Case Rep | 10.1016/j.rmcr.2025.102212 | 2025 | | |
| Colorectal cancer biofilm composition reveals distinct bacterial species signature. | Kushwaha M, Dalal N, Chaudhary S, Ahmed A, Makharia GK, Singh AK, Kumar A. | Appl Microbiol Biotechnol | 10.1007/s00253-025-13537-8 | 2025 | | |
| Transforming Intratumor Bacteria into Immunopotentiators to Reverse Cold Tumors for Enhanced Immuno-chemodynamic Therapy of Triple-Negative Breast Cancer. | Liu X, Sun M, Pu F, Ren J, Qu X. | J Am Chem Soc | 10.1021/jacs.3c09472 | 2023 | | |
| Genetics | Whole-genome sequencing and analysis of a novel strain Streptococcus oralis CRC211 from colorectal tumor. | Shi Y, Liu L, Wu J, Gao M, Sheng K, Hou W, Li X, Wang H. | Microbiome Res Rep | 10.20517/mrr.2025.41 | 2025 | |
| Pathogenicity | Role of LL-37 in Oral Bacterial DNA Accumulation in Dental Plaque. | Tanabe G, Mori T, Araki M, Kataoka H, Into T. | J Dent Res | 10.1177/00220345231210767 | 2024 | |
| Fusobacterium nucleatum promotes anastomotic leakage by activating epithelial cells through the NOD1/RIPK2/ERK signalling pathway to drive IL-1beta-induced neutrophil chemotaxis and collagen degradation. | Wei Z, Bao L, Li B, Yang J, Wang J, Xu F, Wenren H, Zhang K, Shi S, Yan L, Tao X, Zhang T, Wang Z, Liu Y. | Clin Transl Med | 10.1002/ctm2.70262 | 2025 | | |
| The effect of daily usage of Listerine Cool Mint mouthwash on the oropharyngeal microbiome: a substudy of the PReGo trial. | Laumen JGE, Van Dijck C, Manoharan-Basil SS, de Block T, Abdellati S, Xavier BB, Malhotra-Kumar S, Kenyon C. | J Med Microbiol | 10.1099/jmm.0.001830 | 2024 | | |
| Dysregulated genes in HIGK-treated F. nucleatum and their possible association with HNSCC. | Shanmugam SB, Vijayashree Priyadharsini J, Anitha P, Smiline Girija AS, Paramasivam A. | Mol Biol Res Commun | 10.22099/mbrc.2024.50171.1982 | 2025 | | |
| Exploring the Correlation between Selected Oral Commensals and Deoxyribonucleic Acid Degradation in Pulp Tissue Extracted from Primary Teeth Stored in Dry and Wet Conditions: An Ex Vivo Polymerase Chain Reaction Investigation. | Reddy H, Saha S, Nair MR, Shetty V, Dutta K, D'Souza N, Shetty SC. | Int J Clin Pediatr Dent | 10.5005/jp-journals-10005-3043 | 2025 | | |
| An Empirical Dietary Pattern Associated With the Gut Microbial Features in Relation to Colorectal Cancer Risk. | Wang K, Lo CH, Mehta RS, Nguyen LH, Wang Y, Ma W, Ugai T, Kawamura H, Ugai S, Takashima Y, Mima K, Arima K, Okadome K, Giannakis M, Sears CL, Meyerhardt JA, Ng K, Segata N, Izard J, Rimm EB, Garrett WS, Huttenhower C, Giovannucci EL, Chan AT, Ogino S, Song M. | Gastroenterology | 10.1053/j.gastro.2024.07.040 | 2024 | | |
| Macrophage migration inhibitory factor-mediated mast cell extracellular traps induce inflammatory responses upon Fusobacterium nucleatum infection. | Tada H, Nishioka T, Ishiyama R, Song LT, Onoue S, Kawahara K, Nemoto E, Matsushita K, Sugawara S. | Biochem Biophys Res Commun | 10.1016/j.bbrc.2023.06.060 | 2023 | | |
| Effect of periodontitis induced by Fusobacterium nucleatum on the microbiota of the gut and surrounding organs. | Lee S, Haraga H, Satoh T, Mutoh N, Watanabe K, Hamada N, Tani-Ishii N. | Odontology | 10.1007/s10266-023-00827-8 | 2024 | | |
| Biosynthesis of meso-lanthionine in Fusobacterium nucleatum. | Darbyshire A, Mothersole R, Wolthers KR. | Arch Biochem Biophys | 10.1016/j.abb.2023.109666 | 2023 | | |
| Limosilactobacillus reuteri DSM 17938 Inhibition of Biofilm Formation by Prevotella intermedia and Fusobacterium nucleatum Across Salivary pH: An In Vitro Study. | Ananda N, Julia V, Bachtiar EW. | Eur J Dent | 10.1055/s-0044-1786846 | 2025 | | |
| Association of Fusobacterium nucleatum infection with colorectal cancer in Kazakhstani patients. | Kulmambetova G, Kurentay B, Gusmaulemova A, Utupov T, Auganova D, Tarlykov P, Mamlin M, Khamzina S, Shalekenov S, Kozhakhmetov A. | Front Oncol | 10.3389/fonc.2024.1473575 | 2024 | | |
| In vitro assessment of cytokine release from gingival fibroblasts exposed to periodontal pathogens. | Tripathi KP, Mishra R, Choubey V, Kumar A, Aglawe A, Gulati A. | Bioinformation | 10.6026/973206300211501 | 2025 | | |
| Characterization of a Structurally Distinct ATP-Dependent Reactivating Factor of Adenosylcobalamin-Dependent Lysine 5,6-Aminomutase. | Darbyshire AL, Wolthers KR. | Biochemistry | 10.1021/acs.biochem.3c00653 | 2024 | | |
| Effectiveness of photodynamic therapy adjunct to oral debridement in improving clinical, microbiological, and pain in necrotizing ulcerative gingivitis. | Al-Kheraif AA, Javed R, Al-Momani MM, Wasi A, Khan AA. | J Biophotonics | 10.1002/jbio.202300197 | 2023 | | |
| Can bacteria F. nucleatum be actively involved in colon cancer progression via a radical mediated mechanism? | Stokowa-Soltys K, Kierpiec K, Szczerba K, Wieczorek R. | J Inorg Biochem | 10.1016/j.jinorgbio.2023.112307 | 2023 | | |
| Strain specificity in fusobacterial co-aggregation with colorectal cancer-relevant species. | Robinson AV, Allen-Vercoe E. | Anaerobe | 10.1016/j.anaerobe.2023.102758 | 2023 | | |
| Glycosylation of oral bacteria in modulating adhesion and biofilm formation. | Yi S, Liu Y, Wu Q, Zhao D, Li Z, Peng X, Liao G, Wang S. | J Oral Microbiol | 10.1080/20002297.2025.2486650 | 2025 | | |
| Fusobacterium nucleatum and Treponema denticola are robust biomarkers for gingivitis and periodontitis in small dogs. | Kwon D, Bae K, Jang K, Jo HM, Kang SS, Byun J, Kim SE. | Front Vet Sci | 10.3389/fvets.2024.1515521 | 2024 | | |
| Genetics | Diagnostic value of metagenomic next-generation sequencing combined by medical thoracoscopy surgery among infectious pleural effusion patients. | Gao N, Feng S, Yu X, Zhao J, Wan Y, Yao Z, Li D. | BMC Infect Dis | 10.1186/s12879-025-10806-9 | 2025 | |
| Application of targeted next-generation sequencing for pathogens diagnosis and drug resistance prediction in bronchoalveolar lavage fluid of pulmonary infections. | Xu Q, Chen Q, Qiu W, Liu L, Zeng W, Chen J, Li Y, Guo Z, Rong L, Chen B, Yao J, Yang L. | Front Cell Infect Microbiol | 10.3389/fcimb.2025.1590881 | 2025 | | |
| A new model of in vitro dentin intratubular contamination for Fusobacterium nucleatum: Validation by confocal laser scanning microscopy | Barros MC, Pedrinha VF, Graeff MSZ, Bramante CM, Duarte MAH, de Andrade FB. | Heliyon. | 2023 | | ||
| Pathogenicity | Association between periodontal disease and prostate disease: a mini review. | Li S, Cao H, Zhang Y, Yang T, Li M, Lv C, Lian X. | Front Cell Infect Microbiol | 10.3389/fcimb.2025.1669490 | 2025 | |
| Culture-Negative Fusobacterium nucleatum Brain Abscess and Pleural Empyema Cases Revealed by 16S rRNA Sequencing. | Park K, Hur KH, Sung H, Kim MN. | Clin Lab | 10.7754/clin.lab.2022.220722 | 2023 | | |
| Not Just Another Facial Abscess: Cervicofacial Actinomycosis Uncovered by Skin Biopsy. | Kresch-Vatch M, Moreno BA, Lutwak M, Lutwak D, Skopit S. | Cureus | 10.7759/cureus.91337 | 2025 | | |
| Intratumoural pks+Escherichia coli is associated with risk of metachronous colorectal cancer and adenoma development in people with Lynch syndrome. | Chu YL, Georgeson P, Clendenning M, Mahmood K, Walker R, Como J, Joseland S, Preston SG, Rice T, Lynch BM, Milne RL, Southey MC, Giles GG, Phipps AI, Hopper JL, Win AK, Rosty C, Macrae FA, Winship I, Jenkins MA, Buchanan DD, Joo JE. | EBioMedicine | 10.1016/j.ebiom.2025.105661 | 2025 | | |
| The Interplay Between the Gut Microbiota and Colorectal Cancer: A Review of the Literature. | Cintoni M, Palombaro M, Zoli E, D'Agostino G, Pulcini G, Leonardi E, Raoul P, Rinninella E, De Maio F, Capristo E, Gasbarrini A, Mele MC. | Microorganisms | 10.3390/microorganisms13061410 | 2025 | | |
| Association of Gut Microbiota With Performance Level Among Iranian Professional and Semi-Professional Runners: A Cross-Sectional Study. | Nazari H, Meibodi AE, Bassami M, Olfatifar M, Yadegar A. | Health Sci Rep | 10.1002/hsr2.71319 | 2025 | | |
| Comparative Evaluation of Microbial Flora of Endodontic Origin in Teeth with Endo-Perio Lesions. | Mahajan A, Razi MA, Kundu M, Qamar S, Chandra S, Deep A. | J Pharm Bioallied Sci | 10.4103/jpbs.jpbs_1060_23 | 2024 | | |
| Lactobacillus lysates protect oral epithelial cells from pathogen-associated damage, increase secretion of pro-inflammatory cytokines and enhance barrier integrity. | Mercer SD, Doherty C, Singh G, Willmott T, Cheesapcharoen T, Teanpaisan R, O'Neill C, Ledder RG, McBain AJ. | Sci Rep | 10.1038/s41598-025-86914-y | 2025 | | |
| Oral Administration of Lactobacillus acidophilus LA5 Prevents Alveolar Bone Loss and Alters Oral and Gut Microbiomes in a Murine Periodontitis Experimental Model. | Cataruci ACS, Kawamoto D, Shimabukuro N, Ishikawa KH, Ando-Suguimoto ES, Ribeiro RA, Nicastro GG, Albuquerque-Souza E, de Souza RF, Mayer MPA. | Microorganisms | 10.3390/microorganisms12061057 | 2024 | | |
| Phylogeny | Long-read 16S rRNA amplicon sequencing reveals microbial characteristics in patients with colorectal adenomas and carcinoma lesions in Egypt. | El Leithy AA, Youssef ASE, Nassar A, Aziz RK, Khaled NM, Mahrous MT, Farahat GN, Mohamed AH, Bakr YM. | Gut Pathog | 10.1186/s13099-025-00681-9 | 2025 | |
| Bacterial Volatile Organic Compounds as Potential Caries and Periodontitis Disease Biomarkers. | Haiek M, Dvoyris V, Broza YY, Haick H, Weiss E, Houri-Haddad Y. | Int J Mol Sci | 10.3390/ijms26083591 | 2025 | | |
| Can Salivary Biomarkers Serve as Diagnostic and Prognostic Tools for Early Detection in Patients with Colorectal Cancer? A Systematic Review. | Krokosz S, Obrycka M, Zalewska A. | Curr Issues Mol Biol | 10.3390/cimb47080647 | 2025 | | |
| Phylogeny | Differences in gut microbiota among patients with anastomotic leak following colorectal cancer surgery. | Yan J, Wang Q, Li Q, Lu J, Tong Q. | Front Microbiol | 10.3389/fmicb.2025.1578990 | 2025 | |
| Metagenomic Signatures of Colorectal Cancer in the Jordanian Population: A Regional Case-Control Analysis Using 16S rRNA Profiling | Alanagreh L, Mustafa M, Al-Zghoul M, Massadeh M, Batiha O, Sughayer M, Almashakbeh R, Abu Suilike H, Tout F, Alzoughool F. | Microorganisms | 2025 | | ||
| Microbiota in colorectal cancer related to liver metastasis. | Wei P, Han W, Zhang Z, Tian X, Yang C, Wang Q, Xie W, Liu Y, Gao Y, Chang H. | Chin J Cancer Res | 10.21147/j.issn.1000-9604.2024.01.02 | 2024 | | |
| Large Lung Abscess Caused by Fusobacterium nucleatum. | Kami W, Baba M, Chinen T, Fujita J. | Intern Med | 10.2169/internalmedicine.1751-23 | 2023 | | |
| [The Relationship of Enterotoxigenic Bacteroides fragilis and Fusobacterium nucleatum Intestinal Colonization with Colorectal Cancer: A Case-Control Study Performed with Colon Biopsies]. | Ozturk Bakar Y, Demiryas S, Ceylan Kilincarslan A, Demirci M, Kepil N, Bakar MT, Taner Z, Tokuc E, Ziyad MA, Tasci I, Kocazeybek BS, Bahar Tokman H. | Mikrobiyol Bul | 10.5578/mb.20239929 | 2023 | | |
| Oral microbiota: the overlooked catalyst in cancer initiation and progression. | Wang X, He X, Zhong B. | Front Cell Dev Biol | 10.3389/fcell.2024.1479720 | 2024 | | |
| Microbial manipulators: Fusobacterium nucleatum modulates the tumor immune microenvironment in colorectal cancer. | Li Q, Luo W, Xiao L, Xu X, Peng X, Cheng L, Zhou X, Zheng X. | J Oral Microbiol | 10.1080/20002297.2025.2544169 | 2025 | | |
| Discovery of potent natural product higenamine derivatives as novel Anti-Fusobacterium nucleatum agents. | Su S, Bu Q, Bai X, Huang Y, Wang F, Hong J, Fang JY, Wu S, Sheng C. | Bioorg Chem | 10.1016/j.bioorg.2023.106586 | 2023 | | |
| Biofilm architecture and dynamics of the oral ecosystem. | Ray RR. | BioTechnologia (Pozn) | 10.5114/bta.2024.145259 | 2024 | | |
| Quantitative Assessment of the Post-translational Modifications of Human Serum Albumin by Dimethyl Trisulfide. | Koshiishi I, Nagai S, Yuzawa Y, Takigawa Y. | Biol Pharm Bull | 10.1248/bpb.b23-00793 | 2024 | | |
| Lemierre's Syndrome: An Unlikely Diagnosis in a Patient Presenting with Diarrhoea and Vomiting, or Maybe not? | Papaleontiou G, Young A. | Eur J Case Rep Intern Med | 10.12890/2025_005063 | 2025 | | |
| Membrane-anchoring selenophene viologens for antibacterial photodynamic therapy against periodontitis via restoring subgingival flora and alleviating inflammation. | Ding R, Liu X, Zhao X, Sun Q, Cheng Y, Li A, Pei D, He G. | Biomaterials | 10.1016/j.biomaterials.2024.122536 | 2024 | | |
| The Gut Microbiome and Its Multifaceted Role in Cancer Metabolism, Initiation, and Progression: Insights and Therapeutic Implications. | Xu K, Motiwala Z, Corona-Avila I, Makhanasa D, Alkahalifeh L, Khan MW. | Technol Cancer Res Treat | 10.1177/15330338251331960 | 2025 | | |
| The current status and prospects of gut microbiota combined with PD-1/PD-L1 inhibitors in the treatment of colorectal cancer: a review. | Deng M, Li X, Wu H, Xue D, Wang Y, Guo R, Cui Y, Jin C, Luo F, Li H. | BMC Gastroenterol | 10.1186/s12876-025-03968-y | 2025 | | |
| Pathogenicity | The role of oral microbiota in lung carcinogenesis through the oral-lung axis: a comprehensive review of mechanisms and therapeutic potential | Zhou M, Liu Y, Yin X, Gong J, Li J. | Discov Oncol | 2025 | | |
| Transcriptome | Metatranscriptome and Resistome of the Endodontic Microbiome. | Pinheiro ET, Karygianni L, Candeiro GTM, Vilela BG, Dantas LO, Pereira ACC, Gomes BPFA, Attin T, Thurnheer T, Russo G. | J Endod | 10.1016/j.joen.2024.03.015 | 2024 | |
| Microbiota as diagnostic biomarkers: advancing early cancer detection and personalized therapeutic approaches through microbiome profiling. | Eslami M, Naderian R, Bahar A, Babaeizad A, Rezanavaz Gheshlagh S, Oksenych V, Tahmasebi H. | Front Immunol | 10.3389/fimmu.2025.1559480 | 2025 | | |
| A retrospective study on the impact of different antibiotic regimens in non-surgical periodontal therapy on microbial loads and therapy outcomes. | Werner N, Pitchika V, Heck K, Ern C, Heym R, Al-Ahmad A, Cieplik F, Schwendicke F, Bumm CV, Folwaczny M. | Front Oral Health | 10.3389/froh.2025.1578484 | 2025 | | |
| Collateral pathways arising from internal jugular venous occlusion in Lemierre's syndrome. | Ishikawa K, Mori N. | Clin Case Rep | 10.1002/ccr3.9338 | 2024 | | |
| Emerging Non-Invasive Biomarkers for Early Detection of Gastrointestinal Cancers. | Singh A, Kesani H, Saleh TM, Rai M. | Cureus | 10.7759/cureus.92296 | 2025 | | |
| Decoding the microbial-local immune dialogue in liver cancer: from ecological drivers to precision therapeutics. | Xu Y, Wen B, Gao N, Liu S. | Front Oncol | 10.3389/fonc.2025.1629479 | 2025 | | |
| Transcriptome | Complete genome and transcriptome datasets of Streptococcus salivarius strains from healthy Korean subjects. | Jang EY, Moon JH, Lee JH. | Sci Data | 10.1038/s41597-025-04619-3 | 2025 | |
| Antimicrobial efficacy of extracts obtained from aerial part, leaves, and flowers of Sphaeranthus indicus on different periodontal pathogens: An in vitro study. | Gawade MR, Agrawal AA, Sreeram M, Mohan M. | J Indian Soc Periodontol | 10.4103/jisp.jisp_397_23 | 2024 | | |
| Fusobacterium nucleatum and non-coding RNAs: orchestrating oncogenic pathways in colorectal cancer. | Sadeghloo Z, Ebrahimi S, Hakemi-Vala M, Totonchi M, Sadeghi A, Fatemi N. | Gut Pathog | 10.1186/s13099-025-00757-6 | 2025 | | |
| Genetics | Porphyromonas gingivalis and Fusobacterium nucleatum synergistically strengthen the effect of promoting oral squamous cell carcinoma progression | Song X, Wang J, Gu Z, Qiu X, Yuan M, Ke H, Deng R. | Infect Agent Cancer | 2025 | | |
| Relationship between gut microbiome Fusobacterium nucleatum and LINE-1 methylation level in esophageal cancer. | Baba Y, Hara Y, Toihata T, Kosumi K, Iwatsuki M, Iwagami S, Miyamoto Y, Yoshida N, Komohara Y, Baba H. | Esophagus | 10.1007/s10388-023-01009-9 | 2023 | | |
| Adhesin RadD: the secret weapon of Fusobacterium nucleatum. | Jia D, Chen S. | Gut Microbes | 10.1080/19490976.2024.2426617 | 2024 | | |
| Gut Microbiota and Colorectal Cancer: A Balance Between Risk and Protection. | Ionescu VA, Diaconu CC, Gheorghe G, Mihai MM, Diaconu CC, Bostan M, Bleotu C. | Int J Mol Sci | 10.3390/ijms26083733 | 2025 | | |
| Expanding the beta-substitution reactions of serine synthase through mutagenesis of aromatic active site residues. | Darbyshire AL, Wolthers KR. | Arch Biochem Biophys | 10.1016/j.abb.2023.109727 | 2023 | | |
| Metabolism | Inactivation of the Fusobacterium nucleatum Rnf complex reduces FadA-mediated amyloid formation and tumor development. | Britton TA, Lee JH, Chang C, Bhat AH, Chen Y-W, Mohammed Ali R, Wu C, Das A, Ton-That H. | mBio | 10.1128/mbio.01032-25 | 2025 | |
| Impact of Fusobacterium nucleatum in the treatment of cancer, including radiotherapy and its future potential in esophageal cancer. | Ohsawa M, Nishi H, Emi M, Yoshikawa T, Hamai Y, Ibuki Y, Kurokawa T, Hirohata R, Kitasaki N, Kawada-Matsuo M, Komatsuzawa H, Kawaguchi H, Okada M. | J Radiat Res | 10.1093/jrr/rrae061 | 2024 | | |
| Pathogenicity | Fusobacterium nucleatum, immune responses, and metastatic organ diversity in colorectal cancer liver metastasis. | Shigematsu Y, Saito R, Amori G, Kanda H, Takahashi Y, Takeuchi K, Takahashi S, Inamura K. | Cancer Sci | 10.1111/cas.16315 | 2024 | |
| Molecular determinants of Neu5Ac binding to a tripartite ATP independent periplasmic (TRAP) transporter. | Goyal P, Dhanabalan K, Scalise M, Friemann R, Indiveri C, Dobson RCJ, Vinothkumar KR, Ramaswamy S. | Elife | 10.7554/elife.98158 | 2025 | | |
| Comparison of the Antimicrobial Effect of Hydrogen Water and Chlorhexidine Mouth rinse in Toothbrush Disinfection Among Dental Students. | Vaishnavi C, Elangovan GP, Thirumal M, Prashanth SV, Deepika D, Pragathi TG. | J Pharm Bioallied Sci | 10.4103/jpbs.jpbs_1565_24 | 2025 | | |
| Metagenomic next-generation sequencing identified a brain abscess caused by mixed oral anaerobe infection: A case report. | Ma Z, Liu H, Liu M, Wang Y, Li C, Xu Y. | Infect Med (Beijing) | 10.1016/j.imj.2024.100109 | 2024 | | |
| Comprehensive evaluation and progress of colorectal cancer screening methods. | Jiaqun H, Jing Z, Yunfeng Y, Yiren H, Yinhang W, Shuwen H, Wei W. | Gut Pathog | 10.1186/s13099-025-00751-y | 2025 | | |
| Human calculus adhesive-induced periodontitis model recapitulating human periodontitis microbiota in rats. | You Y, Wu HL, Chen DY, Yu SY, Xu Y, Tang Y, Sun HL, Huang C. | BMC Oral Health | 10.1186/s12903-025-06398-0 | 2025 | | |
| [Expression, purification, and characterization of the histidine kinase CarS from Fusobacterium nucleatum]. | Li Z, Shi X, Fan R, Wang L, Bu T, Zheng W, Zhang X, Quan C. | Sheng Wu Gong Cheng Xue Bao | 10.13345/j.cjb.220779 | 2023 | | |
| Microbial signatures in metastatic cancer. | Bautista J, Fuentes-Yepez MP, Adatty-Molina J, Lopez-Cortes A. | Front Med (Lausanne) | 10.3389/fmed.2025.1654792 | 2025 | | |
| Association of Root Biofilm Bacteriome with Root Caries Lesion Severity and Activity. | Usuga-Vacca M, Marquez-Ortiz RA, Castellanos JE, Martignon S. | Caries Res | 10.1159/000535923 | 2024 | | |
| Possible roles of short-chain fatty acids produced by oral bacteria in the development of alveolar osteitis. | Asayama T, Takada A, Mikami Y, Yamaguchi H, Tamura M, Matsumoto K, Miyake K, Yonehara Y, Tsuda H. | J Oral Sci | 10.2334/josnusd.23-0410 | 2024 | | |
| Antibiofilm efficacy of a calcium silicate-based intracanal medicament against Fusobacterium nucleatum strains. | Balto H, Barakat R, Basudan S, Fakeeha G, Alharbi SR, Almohareb R. | Sci Rep | 10.1038/s41598-024-77130-1 | 2024 | | |
| Synergistic Potential of Antibiotics with Cancer Treatments. | Nardo G, Pantziarka P, Conti M. | Cancers (Basel) | 10.3390/cancers17010059 | 2024 | | |
| The Effects of Nicotine Pouches and E-Cigarettes on Oral Microbes: A Pilot Study. | Miluna-Meldere S, Rostoka D, Broks R, Viksne K, Ciematnieks R, Skadins I, Kroica J. | Microorganisms | 10.3390/microorganisms12081514 | 2024 | | |
| Indoxyl sulfate contributes to colorectal cancer cell proliferation and increased EGFR expression by activating AhR and Akt. | Ichisaka Y, Yano S, Nishimura K, Niwa T, Shimizu H. | Biomed Res | 10.2220/biomedres.45.57 | 2024 | | |
| Crosstalk Between Oral Microbiome and Cancer: Emerging Trends and Insights. | Yang S, Hao S, Ye H, Zhang X. | Can J Infect Dis Med Microbiol | 10.1155/cjid/6639127 | 2025 | | |
| Role of Antimicrobial Peptides in Periodontal Health and Disease-A Review. | Patil RT, Dhadse PV, Wankhede AN, Punse SD. | J Pharm Bioallied Sci | 10.4103/jpbs.jpbs_1668_24 | 2025 | | |
| Genetics | Draft genome sequence of a Fusobacterium nucleatum strain isolated from a patient in Kazakhstan with colorectal cancer. | Kulmambetova G, Utupov T, Kurentay B, Auganova D, Tarlykov P, Shevtsov A, Daniyarov A, Khamzina S, Mamlin M, Kozhakhmetov A, Shalekenov S. | Microbiol Resour Announc | 10.1128/mra.00367-23 | 2023 | |
| Possible correlation of specific bacteria detected by using a novel screening method and periodontal disease in dogs. | Takahashi K, Arima E, Sawayama H, Suda A, Miura N, Shirakata Y, Ito S, Suda Y. | J Vet Med Sci | 10.1292/jvms.25-0004 | 2025 | | |
| Comparative clinical characterization of microflora between primary and secondary endodontic infections-An in vivo cross sectional study. | Yeli M, Naik B, Kulkarni R, Kamath V, Moogi P, Patil S, Bhat K. | J Oral Biol Craniofac Res | 10.1016/j.jobcr.2025.09.018 | 2025 | | |
| "Friends" that come with man's best friend: <i>Capnocytophaga canimorsus</i> sepsis and meningitis in an immunocompromised patient. | Tao L, Freiberg JA, Humphries R. | ASM Case Rep | 10.1128/asmcr.00085-24 | 2025 | | |
| Oncomicrobial vaccines: The potential for a Fusobacterium nucleatum vaccine to improve colorectal cancer outcomes. | Holt RA. | Cell Host Microbe | 10.1016/j.chom.2022.11.014 | 2023 | | |
| FadA antigen of Fusobacterium nucleatum: implications for ceRNA network in colorectal cancer and adenomatous polyps progression. | Rezasoltani S, Shams E, Piroozkhah M, Aidi Y, Azizmohammad Looha M, Bagheri P, Behzadi Andouhjerdi R, Sadeghi A, Rejali L, Nazemalhosseini-Mojarad E. | Discov Oncol | 10.1007/s12672-025-01796-w | 2025 | | |
| Development of gastric mucosa-associated microbiota in autoimmune gastritis with neuroendocrine tumors. | Otani K, Nakatsu G, Fujimoto K, Miyaoka D, Sato N, Nadatani Y, Nishida Y, Maruyama H, Ominami M, Fukunaga S, Hosomi S, Tanaka F, Imoto S, Uematsu S, Watanabe T, Fujiwara Y. | J Gastroenterol | 10.1007/s00535-025-02298-w | 2025 | | |
| Fusobacterium nucleatum aggravates rheumatoid arthritis through FadA-containing outer membrane vesicles. | Hong M, Li Z, Liu H, Zheng S, Zhang F, Zhu J, Shi H, Ye H, Chou Z, Gao L, Diao J, Zhang Y, Zhang D, Chen S, Zhou H, Li J. | Cell Host Microbe | 10.1016/j.chom.2023.03.018 | 2023 | | |
| Pathogenicity | An Overview of the Etiopathogenic Mechanisms Involved in the Expression of the Oral Microbiota. | Popovici IA, Orasanu CI, Cozaru GC, Ionescu AC, Kajanto L, Cimpineanu B, Chisoi A, Mitroi AN, Poinareanu I, Voda RI, Ursica OA, Pundiche MB. | Clin Pract | 10.3390/clinpract15040080 | 2025 | |
| Tumor-Targeting Nanoassembly for Enhanced Colorectal Cancer Therapy by Eliminating Intratumoral Fusobacterium nucleatum. | Li X, Ma Y, Xin Y, Ma F, Gao H. | ACS Appl Mater Interfaces | 10.1021/acsami.3c01210 | 2023 | | |
| Polymicrobial Infection Induces Adipose Tissue Dysfunction via Gingival Extracellular Vesicles. | Liu Y, Cui B, Zhang P, Xiao S, Duan D, Ding Y. | J Dent Res | 10.1177/00220345231211210 | 2024 | | |
| Interaction Between Enterococcus faecalis and Fusobacterium nucleatum Regulated Macrophage Transcriptional Profiling and Reprogrammed Cellular Immune and Metabolic Response. | Liang J, Huang W, Chan P, Guo L. | Microorganisms | 10.3390/microorganisms13061351 | 2025 | | |
| Photothermal-promoted multi-functional gallic acid grafted chitosan hydrogel containing tannic acid miniaturized particles for peri-implantitis. | Shen L, Hu J, Yuan Y, Wang X, Jiang Q. | Int J Biol Macromol | 10.1016/j.ijbiomac.2023.127366 | 2023 | | |
| Genetics | The physical biogeography of Fusobacterium nucleatum in health and disease. | Connolly JP, Kelly L. | mBio | 10.1128/mbio.02989-24 | 2025 | |
| Pathogenicity | The association between periodontal microbial biomarkers and primary therapy outcome. | Werner N, Frasheri I, Heck K, Ern C, Heym R, Bumm CV, Folwaczny M. | Clin Oral Investig | 10.1007/s00784-024-05904-y | 2024 | |
| [Effects of Fusobacterium nucleus derived outer membrane vesicles on claudin-4 expression in oral epithelial cells]. | Yang CL, Yang M, Wang YF, Song CC, DU GH, Tang GY. | Shanghai Kou Qiang Yi Xue | 2023 | | ||
| Periodontitis exacerbates atherosclerosis through Fusobacterium nucleatum-promoted hepatic glycolysis and lipogenesis. | Zhou LJ, Lin WZ, Meng XQ, Zhu H, Liu T, Du LJ, Bai XB, Chen BY, Liu Y, Xu Y, Xie Y, Shu R, Chen FM, Zhu YQ, Duan SZ. | Cardiovasc Res | 10.1093/cvr/cvad045 | 2023 | | |
| Pathogenicity | Non-Invasive Physical Plasma Reduces the Inflammatory Response in Microbially Prestimulated Human Gingival Fibroblasts. | Eggers B, Stope MB, Marciniak J, Mustea A, Eick S, Deschner J, Nokhbehsaim M, Kramer FJ. | Int J Mol Sci | 10.3390/ijms242216156 | 2023 | |
| [The oral microbiome in the context of systemic disease]. | Leonov GE, Varaeva YR, Livantsova EN, Starodubova AV. | Vopr Pitan | 10.33029/0042-8833-2023-92-4-6-19 | 2023 | | |
| Feel so bac: is Fusobacterium the suspect causing endometriosis? | Hou HT, Lin TC, Wu MH, Tsai SJ. | Trends Mol Med | 10.1016/j.molmed.2023.08.003 | 2023 | | |
| Amplification-Free Electrochemiluminescent Biosensor for Ultrasensitive Detection of Fusobacterium nucleatum Using Tetrahedral DNA-Based CRISPR/Cas12a. | Zhang X, Wu M, Shi H, Kim S, Lu S, Wang P, Qin J. | Cyborg Bionic Syst | 10.34133/cbsystems.0266 | 2025 | | |
| Four-Week Evaluation of the Interaction Pattern Among Saccharibacteria, Nitrate-Reducing Bacteria, and Periodontopathogens in Orthodontic Miniscrew Implants. | Bachtiar BM, Bachtiar EW, Jakubovics NS, Fath T, Sumardi S, Ismah N, Haerani N, Tadjoedin FM, Radzi Z. | Dent J (Basel) | 10.3390/dj13090405 | 2025 | | |
| An In Vitro Study to Evaluate the Antimicrobial Activity of a Zinc Citrate, Sodium Fluoride, Alum and Xylitol-Based Toothpaste Formulation. | Shukla K, Kiran Pebbili K, Bhagat SV, Kaushik K, Sanghavi AP, Kotak BP. | Cureus | 10.7759/cureus.59413 | 2024 | | |
| Pathogenicity | Gut microbiota in gastric cancer: from pathogenesis to precision medicine | Huo S, Lv K, Han L, Zhao Y, Jiang J. | Front Microbiol | 2025 | | |
| Differences in sputum microbiota based on cure status of patients with nontuberculous mycobacterial pulmonary disease. | Kang N, Kim SY, Kim DH, Jhun BW. | Korean J Intern Med | 10.3904/kjim.2024.209 | 2025 | | |
| Proliferative verrucous leukoplakia is associated with aggressive periodontal pathogens: a comparative study with oral lichen planus and chronic periodontitis cases. | Liska J, Liskova V, Molnarova N, Topolcan O, Posta P, Hauer L. | Clin Oral Investig | 10.1007/s00784-025-06525-9 | 2025 | | |
| Intratumoral microbial abundance and load influence the immune microenvironment of oral squamous cell carcinoma. | Fang J, Wu M, Shen H, Liu W, Zhang T. | Front Oncol | 10.3389/fonc.2025.1616928 | 2025 | | |
| Gut microbiota in colorectal cancer: a review of its influence on tumor immune surveillance and therapeutic response. | Zhang C, Wang Y, Cheng L, Cao X, Liu C. | Front Oncol | 10.3389/fonc.2025.1557959 | 2025 | | |
| Phylogeny | Association of Fusobacterium nucleatum in human saliva with periodontal status and composition of the salivary microbiome including periodontopathogens. | Akase T, Inubushi J, Hayashi-Okada Y, Shimizu Y. | Microbiol Spectr | 10.1128/spectrum.00855-24 | 2024 | |
| Severe pneumonia caused by Legionella pneumophila associated with Tropheryma whipplei: A case report. | Jin D, Li F, Fang J, Wang J, Li ST. | Medicine (Baltimore) | 10.1097/md.0000000000043121 | 2025 | | |
| Gut microbiota and gastrointestinal tumors: insights from a bibliometric analysis. | Chen C, Wang X, Han X, Peng L, Zhang Z. | Front Microbiol | 10.3389/fmicb.2025.1558490 | 2025 | | |
| Isolation of Fusobacterium nucleatum from human feces using immunomagnetic separation coupled with fastidious anaerobe agar. | Tang J, Dun G, Li J, Xu Q, Zhang T, Lan Y, Zeng L, Luo H, Xiang Y, Tang B, Zeng D. | J Appl Microbiol | 10.1093/jambio/lxac058 | 2023 | | |
| A Longitudinal Dynamic Change in LMR Can Be a Biomarker for Recurrence in Fusobacterium Nucleatum-Positive Colorectal Cancer Patients. | Chen S, Chang WH, Zhang J, Liu XY, Gao T, Qi XW, Cai DY, Mao Y, Lu TX. | J Inflamm Res | 10.2147/jir.s489432 | 2024 | | |
| The intratumor microbiota and thyroid cancer: a review. | Liu S, Xiong X, Hao T, Shi X, Zhao Y. | Front Endocrinol (Lausanne) | 10.3389/fendo.2025.1536155 | 2025 | | |
| A Novel Bacteriophage with the Potential to Inhibit Fusobacterium nucleatum-Induced Proliferation of Colorectal Cancer Cells. | Lam HYP, Lai MJ, Wang PC, Wu WJ, Chen LK, Fan HW, Tseng CC, Peng SY, Chang KC. | Antibiotics (Basel) | 10.3390/antibiotics14010045 | 2025 | | |
| In search of oral cosmetics from nature: A review of medicinal plants for dental care in West Africa | Makgobole MU, Onwubu SC, Nxumal CT, Mpofana N, Ayokun-nun Ajao A. | S Afr J Bot | 2023 | | ||
| Micro-implant anchorage in adolescent orthodontics: a promising and advantageous option. | Xu Y, Ying K, Lang X, Xu C. | Am J Transl Res | 10.62347/morq8289 | 2025 | | |
| Appendectomy and Long-term Colorectal Cancer Incidence, Overall and by Tumor Fusobacterium nucleatum Status. | Kawamura H, Ugai T, Takashima Y, Okadome K, Shimizu T, Mima K, Akimoto N, Haruki K, Arima K, Zhao M, Vayrynen JP, Wu K, Zhang X, Ng K, Nowak JA, Meyerhardt JA, Giovannucci EL, Giannakis M, Chan AT, Huttenhower C, Garrett WS, Song M, Ogino S. | Ann Surg | 10.1097/sla.0000000000006315 | 2025 | | |
| Prevalence and Severity of Periodontitis in Patients with Ulcerative Colitis: A Case-Control Study. | Soronzonbold A, Khishigdorj O, Duger D, Batbayar B. | Int J Environ Res Public Health | 10.3390/ijerph22091355 | 2025 | | |
| Exploring the Microbiome in Breast Cancer: The Role of Fusobacterium nucleatum as an Onco-Immune Modulator. | D'Angelo A, Zenoniani A, Masci M, Aceto GM, Piattelli A, Curia MC. | Microorganisms | 10.3390/microorganisms13091995 | 2025 | | |
| Metabolism | Tailoring a Functional Synthetic Microbial Community Alleviates Fusobacterium nucleatum-infected Colorectal Cancer via Ecological Control. | Zhou Z, Yang M, Fang H, Zhang B, Ma Y, Li Y, Liu Y, Cheng Z, Zhao Y, Si Z, Zhu H, Chen P. | Adv Sci (Weinh) | 10.1002/advs.202414232 | 2025 | |
| The human microbiome: redefining cancer pathogenesis and therapy. | Adlakha YK, Chhabra R. | Cancer Cell Int | 10.1186/s12935-025-03787-x | 2025 | | |
| Tannerella forsythia, Fusobacterium nucleatum, and Suspected Actinomyces Causing Massive Empyema: A Case Report. | Stewart CE, McCafferty A, Sherertz R. | Cureus | 10.7759/cureus.48117 | 2023 | | |
| Intratumoral microbiota in orchestrating cancer immunotherapy response. | Zou Y, Zhang H, Liu F, Chen ZS, Tang H. | J Transl Int Med | 10.1515/jtim-2024-0038 | 2024 | | |
| The oral-gut microbiota axis in cardiovascular diseases: mechanisms, therapeutic targets, and translational challenges. | Su S, Ni X, Lin Y. | Front Cell Infect Microbiol | 10.3389/fcimb.2025.1658502 | 2025 | | |
| Clinical Picture and Outcomes in Patients Diagnosed with Brain Abscess. | Furman-Dlubala A, Bednarska A, Radkowski M, Paciorek M, Kolodziejska J, Laskus T, Bursa D, Porowski D, Makowiecki M, Hourani A, Mrozek M, Polak K, Kowalska J. | J Clin Med | 10.3390/jcm14207237 | 2025 | | |
| Genetics | A metagenome-wide association study of gut microbiota in hepatitis B virus-related cirrhosis in northwest China. | Feng M, Chai Y, Li J, Wang Q, Zhang D. | Front Genet | 10.3389/fgene.2025.1619911 | 2025 | |
| Saliva biofilm-derived outer membrane vesicles regulate biofilm formation and immune response of oral epithelial cells on titanium surfaces. | Huang B, Liu C, Yang J, Xiang E, Ivanovski S, Han P. | Clin Oral Investig | 10.1007/s00784-023-05454-9 | 2024 | | |
| Efficient titanium surface modified using bifunctional chimeric peptides to prevent biofilm formation by multiple microorganisms. | Geng H, Sun X, Zhang X, Yuan Y. | Colloids Surf B Biointerfaces | 10.1016/j.colsurfb.2023.113534 | 2023 | | |
| Fusobacterium Species in Osteoarticular Infections in Childhood-A Systematic Review with Data Synthesis and a Case Series in the Acetabular and Hip Joint Regions. | Delbruck H, Schroder S, Stapper T, Schacht S, Pappa A, Hildebrand F, Hertwig MK. | Infect Dis Rep | 10.3390/idr17020030 | 2025 | | |
| Pathogenicity | Vitamin D3 Modulates Inflammatory and Antimicrobial Responses in Oral Epithelial Cells Exposed to Periodontitis-Associated Bacteria. | Karaca F, Bloch S, Kendlbacher FL, Behm C, Schaffer C, Andrukhov O. | Int J Mol Sci | 10.3390/ijms26147001 | 2025 | |
| In vitro evaluation of the antimicrobial properties of terpinen-4-ol on apical periodontitis-associated bacteria. | Kamiya H, Haraguchi A, Mitarai H, Yuda A, Wada H, Shuxin W, Ziqing R, Weihao S, Wada N. | J Infect Chemother | 10.1016/j.jiac.2023.10.021 | 2024 | | |
| From microbes to medicine: harnessing the power of the microbiome in esophageal cancer. | Liu X, Li B, Liang L, Han J, Mai S, Liu L. | Front Immunol | 10.3389/fimmu.2024.1450927 | 2024 | | |
| The role of HbA1c in the bidirectional relationship between periodontitis and diabetes and related interventions: a narrative review. | Du Y, Xiao H, Luo R, Li G, Ren Y. | Front Nutr | 10.3389/fnut.2025.1606223 | 2025 | | |
| Phenotype | Association between gut microbiota and CpG island methylator phenotype in colorectal cancer. | Park PH, Keith K, Calendo G, Jelinek J, Madzo J, Gharaibeh RZ, Ghosh J, Sapienza C, Jobin C, Issa JJ. | Gut Microbes | 10.1080/19490976.2024.2363012 | 2024 | |
| Fusobacterium nucleatum-derived succinic acid induces tumor resistance to immunotherapy in colorectal cancer. | Jiang SS, Xie YL, Xiao XY, Kang ZR, Lin XL, Zhang L, Li CS, Qian Y, Xu PP, Leng XX, Wang LW, Tu SP, Zhong M, Zhao G, Chen JX, Wang Z, Liu Q, Hong J, Chen HY, Chen YX, Fang JY. | Cell Host Microbe | 10.1016/j.chom.2023.04.010 | 2023 | | |
| Lemierre syndrome: A case report and literature review on atypical presentation. | Agonafir DB, Diress AE, Saleh AA, Dechasse CJ, Shane DK. | Medicine (Baltimore) | 10.1097/md.0000000000042823 | 2025 | | |
| New advances in oral microbiology and tumor research. | Liang HJ, Tan XY, Li D, Lin C, Huang SY, Nie GC, Guo XF, Zhang ZB, Zhu XN, Tan SK. | World J Clin Oncol | 10.5306/wjco.v16.i7.106981 | 2025 | | |
| Multiple sclerosis patients exhibit oral dysbiosis with decreased early colonizers and lower hypotaurine level. | Fitzjerrells RL, Meza LA, Yadav M, Olalde H, Hoang J, Paullus M, Cherwin C, Cho TA, Brown G, Ganesan SM, Mangalam AK. | NPJ Biofilms Microbiomes | 10.1038/s41522-025-00787-7 | 2025 | | |
| Fusobacterium nucleatum upregulates the immune inhibitory receptor PD-L1 in colorectal cancer cells via the activation of ALPK1. | Duizer C, Salomons M, van Gogh M, Grave S, Schaafsma FA, Stok MJ, Sijbranda M, Kumarasamy Sivasamy R, Willems RJL, de Zoete MR. | Gut Microbes | 10.1080/19490976.2025.2458203 | 2025 | | |
| Targeted elimination of Fusobacterium nucleatum alleviates periodontitis. | Yakar N, Unlu O, Cen L, Hasturk H, Chen T, Shi W, He X, Kantarci A. | J Oral Microbiol | 10.1080/20002297.2024.2388900 | 2024 | | |
| The Role of Microbiota in Upper Gastrointestinal Cancers. | Marasco G, Colecchia L, Salvi D, Bruni A, Capelli C, Dajti E, Barbaro MR, Cremon C, Stanghellini V, Barbara G. | Cancers (Basel) | 10.3390/cancers17101719 | 2025 | | |
| Links between oral microbiome and insulin resistance: Involvement of MAP kinase signaling pathway. | Chang YR, Cheng WC, Hsiao YC, Su GW, Lin SJ, Wei YS, Chou HC, Lin HP, Lin GY, Chan HL. | Biochimie | 10.1016/j.biochi.2023.06.013 | 2023 | | |
| Commensalism of Fusobacterium nucleatum - The dilemma. | Nayak S, Shetty ND, Kamath DG. | J Indian Soc Periodontol | 10.4103/jisp.jisp_286_23 | 2024 | | |
| Fusobacterium nucleatum Extracellular Vesicles Promote Experimental Colitis by Modulating Autophagy via the miR-574-5p/CARD3 Axis. | Wei S, Zhang J, Wu X, Chen M, Huang H, Zeng S, Xiang Z, Li X, Dong W. | Inflamm Bowel Dis | 10.1093/ibd/izac177 | 2023 | | |
| Identification of keystone taxa in root canals and periapical lesions of post-treatment endodontic infections: Next generation microbiome research. | Arias-Moliz MT, Perez-Carrasco V, Uroz-Torres D, Santana Ramos JD, Garcia-Salcedo JA, Soriano M. | Int Endod J | 10.1111/iej.14046 | 2024 | | |
| NO: a key player in microbiome dynamics and cancer pathogenesis. | Jasemi SK, Faridafshar H, Amin MN, Babamohamadi M, Falahati M, Amirian R, Izadi Z. | Front Cell Infect Microbiol | 10.3389/fcimb.2025.1532255 | 2025 | | |
| Oxidative Stress by H2O2 as a Potential Inductor in the Switch from Commensal to Pathogen in Oncogenic Bacterium Fusobacterium nucleatum. | Scano A, Fais S, Ciappina G, Genovese M, Granata B, Montopoli M, Consolo P, Carroccio P, Muscolino P, Ottaiano A, Bignucolo A, Picone A, Toscano E, Orru G, Berretta M. | Antioxidants (Basel) | 10.3390/antiox14030323 | 2025 | | |
| Brain abscess following right maxillary odontogenic infection in a patient with diabetes mellitus: a case report. | Rim K, Seo E, Kwon D, Ahn J, Paeng JY. | J Korean Assoc Oral Maxillofac Surg | 10.5125/jkaoms.2025.51.5.314 | 2025 | | |
| Gut microbiome-based machine learning model for early colorectal cancer and adenoma screening. | Tsai YJ, Lyu WN, Liao NS, Chen PC, Tsai MH, Chuang EY. | Gut Pathog | 10.1186/s13099-025-00750-z | 2025 | | |
| Quantitative investigation of the bacterial content of periodontal abscess samples by real-time PCR. | Ergun E, Toraman E, Baris O, Budak H, Demir T. | J Microbiol Methods | 10.1016/j.mimet.2023.106826 | 2023 | | |
| An Atypical Presentation of a Pyogenic Liver Abscess Caused by Fusobacterium nucleatum Post-ruptured Appendix. | Rathi H, Fatima F, Hassan T, Schultz K. | Cureus | 10.7759/cureus.42895 | 2023 | | |
| Advances in drug resistance and resistance mechanisms of four colorectal cancer-associated gut microbiota. | Gan Y, Yang H, Wang M, Li J. | PeerJ | 10.7717/peerj.19535 | 2025 | | |
| Current Evidence on the Relation Between Microbiota and Oral Cancer-The Role of Fusobacterium nucleatum-A Narrative Review. | Chiscuzzu F, Crescio C, Varrucciu S, Rizzo D, Sali M, Delogu G, Bussu F. | Cancers (Basel) | 10.3390/cancers17020171 | 2025 | | |
| Investigating the role of Candida albicans as a universal substrate for oral bacteria using a transcriptomic approach: implications for interkingdom biofilm control? | Delaney C, Alapati S, Alshehri M, Kubalova D, Veena CLR, Abusrewil S, Short B, Bradshaw D, Brown JL. | APMIS | 10.1111/apm.13327 | 2023 | | |
| Fusobacterium nucleatum Abundance is Associated with Cachexia in Colorectal Cancer Patients: The ColoCare Study. | Ilozumba MN, Lin T, Hardikar S, Byrd DA, Round JL, Stephens WZ, Holowatyj AN, Warby CA, Damerell V, Li CI, Figueiredo JC, Toriola AT, Shibata D, Fillmore GC, Pickron B, Siegel EM, Kahlert C, Florou V, Gigic B, Ose J, Ulrich CM. | Cancer Med | 10.1002/cam4.70431 | 2024 | | |
| Fusobacterium nucleatum Enrichment in Colorectal Tumor Tissue: Associations With Tumor Characteristics and Survival Outcomes | Phipps A, Hill C, Lin G, Malen R, Reedy A, Kahsai O, Ammar H, Curtis K, Ma N, Randolph T, Ma J, Ogino S, Newcomb P, Hullar M. | Gastro Hep Adv | 2025 | | ||
| Exploring the role of the oral microbiome in saliva, sputum, bronchoalveolar fluid, and lung cancer tumor tissue: A systematic review. | Kwiatkowska AM, Guzman JA, Lafaurie GI, Castillo DM, Cardona AF. | Transl Oncol | 10.1016/j.tranon.2025.102557 | 2025 | | |
| Lemierre Syndrome With Atypical Cardiological Involvement and Fatal Outcome. | Jamal A, Mir Jan S, Zafar A, Jaffar M, Ejaz T. | Cureus | 10.7759/cureus.95424 | 2025 | | |
| A rare case of sporadic metastatic colorectal cancer with glioblastoma multiforme: a challenging clinical scenario. | Awad F, Abdallah F, Alhalabieh A, Aljaafreh I, Naserallah S, Lahham EE. | J Surg Case Rep | 10.1093/jscr/rjae708 | 2025 | | |
| Pathogenicity | Periodontitis as a field of cancerization: association with carcinoembryonic antigen in colorectal cancer patients. | Mesa-Lopez MJ, Bravo M, Egea J, El-Amrani S, Bonilla M, Alberca F, Mesa F. | Clin Oral Investig | 10.1007/s00784-025-06399-x | 2025 | |
| Fusobacterium nucleatum aggravates ulcerative colitis through promoting gut microbiota dysbiosis and dysmetabolism. | Lin S, Zhang X, Zhu X, Jiao J, Wu Y, Li Y, Zhao L. | J Periodontol | 10.1002/jper.22-0205 | 2023 | | |
| Diagnostic value of fecal Fusobacterium nucleatum in colorectal cancer. | Xing C, Zhihao L, Ji D. | Arch Med Sci | 10.5114/aoms/174261 | 2023 | | |
| The oral-gut microbiota axis: a link in cardiometabolic diseases. | Xu Q, Wang W, Li Y, Cui J, Zhu M, Liu Y, Liu Y. | NPJ Biofilms Microbiomes | 10.1038/s41522-025-00646-5 | 2025 | | |
| KRAS mutation promotes the colonization of Fusobacterium nucleatum in colorectal cancer by down-regulating SERTAD4. | Chen Y, Zheng Y, Liu S. | J Cell Mol Med | 10.1111/jcmm.70182 | 2024 | | |
| Bacteriophages, Antibiotics and Probiotics: Exploring the Microbial Battlefield of Colorectal Cancer | Volovat C, Cosovanu M, Ostafe M, Augustin I, Volovat C, Georgescu B, Volovat S. | Int J Mol Sci | 2025 | | ||
| Impact of Chemotherapy Alone and in Combination with Immunotherapy on Oral Microbiota in Cancer Patients-A Pilot Study. | Padure A, Talpos-Niculescu IC, Ciordas PD, Romanescu M, Chis AR, Rusu LC, Sirbu IO. | Microorganisms | 10.3390/microorganisms13071565 | 2025 | | |
| Norepinephrine may promote the progression of Fusobacterium nucleatum related colorectal cancer via quorum sensing signalling. | Du X, Tang Z, Yan L, Zhang L, Zheng Q, Zeng X, Hu Q, Tian Q, Liang L, Zhao X, Li J, Zhao M, Fu X. | Virulence | 10.1080/21505594.2024.2350904 | 2024 | | |
| Fusobacterium nucleatum bacteremia complicated with intracranial Porphyromonas gingivalis and HSV-1 infection: a case report and literature review. | Wang S, Tian Y, Wu Y, Yu Z, Zhang J, Zhang J, Liu S. | BMC Infect Dis | 10.1186/s12879-024-09078-6 | 2024 | | |
| Nomogram model for prognosis of early colorectal cancer after endoscopic therapy: integration of intestinal microbiota and clinicopathological parameters. | Zhu Y, Yang F, Meng L, Zhang X, Chang Y, Zhang L. | Front Oncol | 10.3389/fonc.2025.1559045 | 2025 | | |
| Left Atrial Myxoma Infected With Fusobacterium Nucleatum. | Abuelo JM, Garcia Carro J, Caneiro J, El-Diasty M, Fernandez Gonzalez AL. | Port J Card Thorac Vasc Surg | 10.48729/pjctvs.287 | 2022 | | |
| Antimicrobial behavior of titanium coating with chlorhexidine-doped thin film exposed to a biofilm supplemented with nicotine. | Matos AO, Rangel EC, Barao VAR, Gregory RL. | Dent Mater J | 10.4012/dmj.2022-168 | 2023 | | |
| Isolated Fusobacterium nucleatum Growth in the Blood Culture of a Middle-Aged Man With Lumbar Discitis, Surrounding Psoas Abscesses, and an Inferior Vena Cava Thrombus. | Bomphrey L, Hayden A, Plant AJ. | Cureus | 10.7759/cureus.55306 | 2024 | | |
| Role of oral microbiome in oral oncogenesis, tumor progression, and metastasis. | Li R, Xiao L, Gong T, Liu J, Li Y, Zhou X, Li Y, Zheng X. | Mol Oral Microbiol | 10.1111/omi.12403 | 2023 | | |
| Fusobacterium nucleatum, a key pathogenic factor and microbial biomarker for colorectal cancer. | Wang N, Fang JY. | Trends Microbiol | 10.1016/j.tim.2022.08.010 | 2023 | | |
| Pathogenicity | An update on possible alternative therapeutics for future periodontal disease management. | Das V, Vinod V, Biswas L, Kumar A, Biswas R. | J Appl Microbiol | 10.1093/jambio/lxac039 | 2023 | |
| Emerging roles of intratumoral microbiota: a key to novel cancer therapies. | Fang P, Yang J, Zhang H, Shuai D, Li M, Chen L, Liu L. | Front Oncol | 10.3389/fonc.2025.1506577 | 2025 | | |
| The Subgingival Microbial Composition in Health and Periodontitis with Different Probing Depths. | Wang J, Geng Y, Guo J, Peng J, Xu H, Zhao B, Huang S, Qin M, Du W, Tian J. | Microorganisms | 10.3390/microorganisms13040930 | 2025 | | |
| Pathogenicity | The epigenetic influence of diet-induced gut microbiome changes in precision nutrition - a systematic review. | Suleiman KY, Akorede GJ, Afisu B, Onimajesin AO, Saadudeen A, Lawal MO. | Gastroenterol Hepatol Bed Bench | 10.22037/ghfbb.v18i3.3136 | 2025 | |
| The impact of very low birth weight on children's oral health in adolescence. | Davidovich E, Borovitz Y, Sokolover N, Davidovits M, Barak-Mashal T, Polak D. | Sci Rep | 10.1038/s41598-025-21530-4 | 2025 | | |
| PANoptosis in cancer: bridging molecular mechanisms to therapeutic innovations. | Lin JF, Wang TT, Huang RZ, Tan YT, Chen DL, Ju HQ. | Cell Mol Immunol | 10.1038/s41423-025-01329-z | 2025 | | |
| Differences in Non-Pathogenic Lung-Colonizing Bacteria Among Patients with Different Types of Pneumonia: A Retrospective Study. | Hu CY, Yao SF, Li YF, Wang QZ, Li YJ, Sun C, Liu J, Zhao ZX. | Microorganisms | 10.3390/microorganisms13092099 | 2025 | | |
| Exploring the complex interplay between oral Fusobacterium nucleatum infection, periodontitis, and robust microRNA induction, including multiple known oncogenic miRNAs. | Jeepipalli S, C A, Duncan W, Krishna VM, Sahay B, Chan EKL, Kesavalu L. | mSystems | 10.1128/msystems.01732-24 | 2025 | | |
| Fulminant Sepsis and Perinatal Death at 23 Weeks Due to Fusobacterium nucleatum. | Bonasoni MP, Comitini G, Pati M, Bardaro M, Russello G, Carretto E, Dalla Dea G, Palicelli A, Bernardelli G, Chesi E, Gargano G. | Fetal Pediatr Pathol | 10.1080/15513815.2022.2131487 | 2023 | | |
| Is there a difference in fecal microbiota of children with and without voiding dysfunction? | Akarken I, Tarhan H, Sener G, Deliktas H, Cengiz N, Sahin H. | Arch Ital Urol Androl | 10.4081/aiua.2022.4.455 | 2022 | | |
| A Rare Case of Cerebral Abscess due to Fusobacterium nucleatum with Native Aortic Valve Infective Endocarditis and Pyogenic Liver Abscess. | Sulaiman ZI, Sharma D, Rivera Salva J, Rast J, Samra H, Askar G. | J Investig Med High Impact Case Rep | 10.1177/23247096241272014 | 2024 | | |
| Drug sensitivity testing during dental pulp-dentin complex repair: its effect on treatment outcome and prognosis. | Xiao WX, Yang X, Wang M. | Am J Transl Res | 10.62347/icyr9713 | 2024 | | |
| Association Between Diet and Fusobacterium nucleatum in the Feces of Healthy Adults: A Hospital-based Cross-sectional Study. | Narii N, Zha L, Sobue T, Kitamura T, Shiba S, Mizutani S, Yamada T, Yachida S. | Cancer Prev Res (Phila) | 10.1158/1940-6207.capr-22-0399 | 2023 | | |
| Pathogenicity | Physiologically relevant coculture model for oral microbial-host interactions. | Pang Z, Cady NM, Cen L, Schmidt TM, He X, Li J. | Int J Oral Sci | 10.1038/s41368-025-00365-9 | 2025 | |
| Pathogenicity | Comparative proteomics of saliva of healthy and gingivitis individuals from Rio de Janeiro. | da Silva CVF, Bacila Sade Y, Naressi Scapin SM, da Silva-Boghossian CM, de Oliveira Santos E. | Proteomics Clin Appl | 10.1002/prca.202200098 | 2023 | |
| Case report: Analysis of the efficacy and safety of anti-infectious treatment for brain abscess caused by oral anaerobes. | Tian C, Liu J, Chen Z, Li L. | Front Pharmacol | 10.3389/fphar.2025.1506879 | 2025 | | |
| Harnessing intratumoral microbiota: new horizons in immune microenvironment and immunotherapy | Zhang J, You Z, Li X, Hu J, Li J, Jing Z. | J Transl Med | 2025 | | ||
| Long-term systemic antibiotics and surgical treatment can be an effective treatment option for retrobulbar abscesses in rabbits (Oryctolagus cuniculus): 21 cases (2011-2022). | Levy I, Mans C. | J Am Vet Med Assoc | 10.2460/javma.23.05.0226 | 2023 | | |
| Comparative genomic analysis of Fusobacterium nucleatum reveals high intra-species diversity and cgmlst marker construction. | Zhu Q, Dovletgeldiyev A, Shen C, Li K, Hu S, He Z. | Gut Pathog | 10.1186/s13099-023-00570-z | 2023 | | |
| Ameliorative Effect of Saccharomyces cerevisiae JKSP39 on Fusobacterium nucleatum and Dextran Sulfate Sodium-Induced Colitis Mouse Model. | Zeng X, Li X, Yue Y, Wang X, Chen H, Gu Y, Jia H, He Y, Yuan Y, Yue T. | J Agric Food Chem | 10.1021/acs.jafc.2c05338 | 2022 | | |
| Evaluation of antimicrobial efficacy of mineral trioxide aggregate with and without silver nanoparticles: A systematic review and meta-analysis. | Vandekar M, Pendse G, Toprani N, Hulyal SU, Panikkar P, Tewary E. | J Conserv Dent Endod | 10.4103/jcde.jcde_393_25 | 2025 | | |
| The CarSR two-component system directly controls radD expression as a global regulator that senses bacterial coaggregation in Fusobacterium nucleatum. | G C B, Wu C. | J Bacteriol | 10.1128/jb.00529-24 | 2025 | | |
| Pathogenicity | Bibliometric and visualized analysis of the relationship between rheumatoid arthritis and periodontitis-related bacteria using CiteSpace software. | Lin T, Xu Z, Chen J, Wang X, Li Q, Ye B, Hu C. | Front Microbiol | 10.3389/fmicb.2025.1589331 | 2025 | |
| Development of SacB-based counterselection for efficient allelic exchange in Fusobacterium nucleatum. | Zhou P, G C B, Hu B, Wu C. | Microbiol Spectr | 10.1128/spectrum.02066-24 | 2025 | | |
| Reducing the need for colonoscopy with adjusted FIT and FOBT for stool weight and serum Hb levels. | Ghomashi N, Safari F, Noursina A. | Front Med (Lausanne) | 10.3389/fmed.2023.1274024 | 2023 | | |
| Pathogenicity | Genetic and Epigenetic Biomarkers for the Early Oral Cancerization Risk in Periodontitis Patients. | Marmo GM, Munzone M, Polizzi A, Campagna R, Mascitti M, Isola G. | Curr Issues Mol Biol | 10.3390/cimb47110933 | 2025 | |
| ASSOCIATION OF ORAL MICROBIOTA AND PERIODONTAL DISEASE WITH LUNG CANCER: A SYSTEMATIC REVIEW AND META-ANALYSIS. | Zhang K, He C, Qiu Y, Li X, Hu J, Fu B. | J Evid Based Dent Pract | 10.1016/j.jebdp.2023.101897 | 2023 | | |
| Bidirectional roles of neutrophil extracellular traps in oral microbiota carcinogenesis: A systematic review. | Shen J, Lin H, Mo K, Liang Z, Zhang Y, Quan H, Wang X, Zhang C, Chen C. | Transl Oncol | 10.1016/j.tranon.2025.102361 | 2025 | | |
| The structure of the LPS O-chain from five Fusobacterium nucleatum strains CTX47T, CC2_6JVN3, CC2_3FMU1, CC2_1JVN3, HM-996, containing alditol and phosphate in the main chain and development of mouse monoclonal antibodies specific to the O-antigens. | Vinogradov E, St Michael F, Cairns C, Cox AD. | Carbohydr Res | 10.1016/j.carres.2022.108648 | 2022 | | |
| Lactobacillus casei's Antitumor Potential in Colorectal Cancer: Exploring Mechanisms-A Systematic Review. | Abdorrashidi M, Heiat M, Yeganeh AV, Tohidinia A, Alizadeh A, Ramazani A, Gholizadeh H, Pouraskar T, Peypar MH. | Biomed Res Int | 10.1155/bmri/4216722 | 2025 | | |
| Fusobacterium nucleatum promotes proliferation in oesophageal squamous cell carcinoma via AHR/CYP1A1 signalling. | Yin H, Zhang J, Zhang H, Li Q, Qiu H, Hong K, Wang W, Xiao Y, Yu B. | FEBS J | 10.1111/febs.16619 | 2023 | | |
| Localization of Fusobacterium nucleatum in oral squamous cell carcinoma and its possible directly interacting protein molecules: A case series. | He X, Ma X, Meng Z, Han Z, Chen W. | Histol Histopathol | 10.14670/hh-18-560 | 2023 | | |
| Pathogenicity | Ginger as a Potential Remedy for Periodontitis Treatment: A Review on the Present Evidence. | Arefnehzad R, Gerayeli M, Ganjeh S, Badkoob A, Nassajzadeh A, Mahmoudi R, Tebyani M, Rezaei-Tazangi F, Fathi A. | Health Sci Rep | 10.1002/hsr2.71052 | 2025 | |
| Enterococcal autoprobiotics in the complex treatment of colorectal cancer patient receiving chemotherapy: Two case reports and review of literature. | Ermolenko EI, Baryshnikova NV, Kovalis SA, Novilova NS, Orlova VV, Ilyina AS, Kashchenko VA, Leontieva GF, Suvorov AN. | World J Clin Cases | 10.12998/wjcc.v13.i27.107704 | 2025 | | |
| Co-occurrence of periodontal lesions and dental wear in incisor and masticatory teeth in two sheep flocks in Brazil. | Agostinho SD, Borsanelli AC, Campello PL, Saraiva JR, Silva TA, Schweitzer CM, Gaetti-Jardim E, Dutra IDS. | Vet Rec | 10.1002/vetr.3409 | 2024 | | |
| Analysis of microbiological profiles of Indian patients with peri-implantitis and periodontitis. | B Mangalekar S, Sultana M, Mulay A, Vaddalapu H, P Newaskar D, Bacha S, V Manek P, Desai P. | Bioinformation | 10.6026/973206300200615 | 2024 | | |
| Progress on the mechanism of intestinal microbiota against colorectal cancer. | Xing G, Cui Y, Guo Z, Han B, Zhao G. | Front Cell Infect Microbiol | 10.3389/fcimb.2025.1565103 | 2025 | | |
| Atypical Presentation of Papillon-Lefèvre Syndrome: A Case of Isolated Cutaneous Manifestations Without Dental Involvement. | Alrubaiaan M, Almutairi M, Alajroush W. | Reports (MDPI) | 10.3390/reports8040190 | 2025 | | |
| Identification of urinary bacterial genes as biomarkers for non-invasive diagnosis of renal lupus. | Perez-Carrasco V, Soriano-Lerma A, Guzzi C, Garcia-Martin ML, Tello MJ, Linde-Rodriguez A, Sanchez-Martin V, Ortiz-Gonzalez M, PRECISESADS Clinical Consortium, Gutierrez-Fernandez J, Alarcon-Riquelme ME, Soriano M, Maranon C, Garcia-Salcedo JA. | Biomark Res | 10.1186/s40364-025-00828-5 | 2025 | | |
| Structure of the lipopolysaccharide O-antigens from Fusobacterium nucleatum strains HM-994, HM-995, HM-997. | Vinogradov E, St Michael F, Cox AD. | Carbohydr Res | 10.1016/j.carres.2022.108704 | 2022 | | |
| Peri-Implantitis-Associated Microbiota before and after Peri-Implantitis Treatment, the Biofilm "Competitive Balancing" Effect: A Systematic Review of Randomized Controlled Trials. | Di Spirito F, Pisano M, Di Palo MP, Franci G, Rupe A, Fiorino A, Rengo C. | Microorganisms | 10.3390/microorganisms12101965 | 2024 | | |
| Diagnostic and epidemiological landscape of anaerobic bacteria in Europe, 2020-2023 (ANAEuROBE). | Boattini M, Bianco G, Bastos P, Mavromanolaki VE, Maraki S, Spiliopoulou A, Kakouris V, Kalchev Y, Budimir A, Bedenic B, Rubic Z, Licker M, Musuroi C, Juhasz E, Kristof K, Pirs M, Velimirovic I, Berktold M, Liptakova A, Krajcikova A, Drevinek P, Gryndlerova A, Brzychczy-Wloch M, Olechowska-Jarzab A, Bielec F, Brauncajs M, Podsiadly E, Nurzynska G, Zalas-Wiecek P, Riesbeck K, Andersson HS, Tonjum T, Berild JC, Leegaard TM, Rasmussen AN, Schonning K, Glockner S, Rodel J, Badr MT, Hacker GA, Stark D, Hamprecht A, Dudakova A, Jantsch J, Mancini S, Quiblier C, Jacot D, Greub G, Ferniani T, Ambretti S, Calvo M, Stefani S, Schade R, Yusuf E, Koeveringe SVK, Vandamme S, Verroken A, Rodriguez-Villalobos H, Duigou F, Corvec S, Floch P, Massip C, Chainier D, Barraud O, Louissaint MB, Mizrahi A, Ali S, Doyle M, Egan C, McNicholas S, Colomina-Rodriguez J, Torres I, Luengo RG, Escartin MNL, Perez MBV, Halperin AV, Garcia SF, Canton R, Seruca M, Mendes VS, Carvalho D, Cavallo R, Cristino JM, Costa C. | Int J Antimicrob Agents | 10.1016/j.ijantimicag.2025.107478 | 2025 | | |
| Enzymology | Pre-conditioning of gingival epithelial cells with sub-apoptotic concentrations of curcumin prevents pro-inflammatory cytokine release. | Grant MM, Scott AE, Matthews JB, Griffiths HR, Chapple ILC. | J Periodontal Res | 10.1111/jre.13114 | 2023 | |
| Assays with Patient-Derived Organoids to Evaluate the Impact of Microbial Infection on Base Excision Repair (BER) Enzymes. | Sayed IM, Chakraborty A, Das S. | Methods Mol Biol | 10.1007/978-1-0716-3373-1_10 | 2023 | | |
| Metabolism | Microbiota-directed lactic acid depleting nanoenzyme reactivates antitumor immunity and chemosensitivity in hypoxic tumor. | Lan X, Zhang F, Cui G, Hu B, Lai Y, Lin H, Huang H, Zhou D, Yu M, Yao G. | Mater Today Bio | 10.1016/j.mtbio.2025.102493 | 2025 | |
| Secretion of Extracellular Microvesicles Induced by a Fraction of Escherichia coli: Possible Role in Ovarian Cancer with Bacterial Coinfections. | Sierra-Lopez F, Fernandez-Hernandez JC, Baylon-Pacheco L, Hernandez-Ramirez VI, Bravata-Alcantara JC, Iglesias-Vazquez V, Bernardo-Hernandez S, Medrano-Espinosa D, Acosta-Altamirano G, Talamas-Rohana P, Rosales-Encina JL, Sierra-Martinez M. | Int J Mol Sci | 10.3390/ijms262110653 | 2025 | | |
| Mediation effect of intestinal microbiota on the relationship between fiber intake and colorectal cancer. | Shimomura Y, Zha L, Komukai S, Narii N, Sobue T, Kitamura T, Shiba S, Mizutani S, Yamada T, Sawada N, Yachida S. | Int J Cancer | 10.1002/ijc.34398 | 2023 | | |
| Phylogeny | Circulating Bacterial DNA in Colorectal Cancer Patients: The Potential Role of Fusobacterium nucleatum. | Koliarakis I, Lagkouvardos I, Vogiatzoglou K, Tsamandouras I, Intze E, Messaritakis I, Souglakos J, Tsiaoussis J. | Int J Mol Sci | 10.3390/ijms25169025 | 2024 | |
| Tissue-resident Lachnospiraceae family bacteria protect against colorectal carcinogenesis by promoting tumor immune surveillance. | Zhang X, Yu D, Wu D, Gao X, Shao F, Zhao M, Wang J, Ma J, Wang W, Qin X, Chen Y, Xia P, Wang S. | Cell Host Microbe | 10.1016/j.chom.2023.01.013 | 2023 | | |
| Pathogenicity | Role of Oral Bacteria in Mediating Gemcitabine Resistance in Pancreatic Cancer. | Xu G, Jiang Y, Sun C, Brandt BW, Nazmi K, Morelli L, Lencioni G, Giovannetti E, Deng D. | Biomolecules | 10.3390/biom15071018 | 2025 | |
| Case report: Two case reports of cryptogenic brain abscess caused by Fusobacterium nucleatum and literature review. | Zhang Z, Liu J, Su L, Huang W, Pei Y, Huang G, Yang L, Lv S, Yin J, Liu G. | Front Neurosci | 10.3389/fnins.2023.1248493 | 2023 | | |
| Metabolism of Cysteine Conjugates and Production of Flavor Sulfur Compounds by a Carbon-Sulfur Lyase from the Oral Anaerobe Fusobacterium nucleatum. | Neiers F, Gourrat K, Canon F, Schwartz M. | J Agric Food Chem | 10.1021/acs.jafc.2c01727 | 2022 | | |
| Pathogenicity | Feline chronic gingivostomatitis: a thorough systematic review of associated factors. | Sanchez-Vallejo M, Velez-Velasquez P, Correa-Valencia NM. | J Feline Med Surg | 10.1177/1098612x241310590 | 2025 | |
| Fusobacterium nucleatum: Unraveling its potential role in gastric carcinogenesis. | Petkevicius V, Lehr K, Kupcinskas J, Link A. | World J Gastroenterol | 10.3748/wjg.v30.i35.3972 | 2024 | | |
| Microbiological status at intake in relation to clinical periodontal status at intake and the response to non-surgical periodontal therapy-A retrospective analysis. | Tahery I, Ahmadzai F, Valkenburg C, Slot DE, Van der Weijden FGA. | Int J Dent Hyg | 10.1111/idh.12665 | 2023 | | |
| Novel strategies enhancing endodontic disinfection: Antibacterial biodegradable calcium hydroxide nanoparticles in an ex vivo model. | Elmsmari F, Delgado LM, Duran-Sindreu F, Perez RA, Garcia ML, Teule Trull M, Afrashtehfar KI, Gonzalez JA, Sanchez-Lopez E. | Int J Pharm | 10.1016/j.ijpharm.2023.123627 | 2023 | | |
| Association of Intratumoral Microbiota with Prognosis in Patients with Lacrimal Gland Tumor. | Hu J, Yang Y, Feng Y, Yu Y, Song X, Jia R. | Biomedicines | 10.3390/biomedicines13040960 | 2025 | | |
| Multi-Omics Analysis of Ileal Mucosa and Mesentery Before and After Ileocecal Resection in Crohn's Disease. | Xia K, Jiao Y, Zhang L, Gao R, Wang F, Pan Y, Cui S, Lin Y, Wu T, Li L, Wu X, Ruan Y, Sun J, Yin L, Chen C, Lin M. | United European Gastroenterol J | 10.1002/ueg2.70069 | 2025 | | |
| Metagenomic Next-Generation Sequencing Reveals Tannerella forsythia in Lung Abscesses: A Retrospective Case Series Linking Smoking, Oral Health, and Diagnostic Challenges. | Wang W, Mo Q, Ding X, Pan J. | Infect Drug Resist | 10.2147/idr.s542032 | 2025 | | |
| Microbiome Shifts in Peri-Implantitis: Longitudinal Characterization of Dysbiosis and Resolution. | Anuntakarun S, Thaweesapphithak S, Krasaesin A, Prommanee S, Arunyanak S, Kungsadalpipob K, Acharya A, Porntaveetus T, Mattheos N. | Int Dent J | 10.1016/j.identj.2025.100951 | 2025 | | |
| The Gut Microbiota and Colorectal Cancer: Understanding the Link and Exploring Therapeutic Interventions. | Zalila-Kolsi I, Dhieb D, Osman HA, Mekideche H. | Biology (Basel) | 10.3390/biology14030251 | 2025 | | |
| Unveiling the placental bacterial microbiota: implications for maternal and infant health. | Xie Z, Chen Z, Chai Y, Yao W, Ma G. | Front Physiol | 10.3389/fphys.2025.1544216 | 2025 | | |
| Exploring the Microbiome Landscape of Dental Plaque: A Cross-Sectional Analysis in Periodontal Health and Disease. | Boyapati R, Lanke RB, Mudaliyar MC, Gaddam B, Babu Dasari A, Dhulipalla R. | Cureus | 10.7759/cureus.57334 | 2024 | | |
| Pathogenicity | Structural basis for immune cell binding of Fusobacterium nucleatum via the trimeric autotransporter adhesin CbpF. | Marongiu GL, Fink U, Schopf F, Oder A, von Kries JP, Roderer D. | Proc Natl Acad Sci U S A | 10.1073/pnas.2418155122 | 2025 | |
| Antibacterial activity of 1 % Roselle flower nano-emulsion extract (Hibiscus sabdariffa) against peri-implantitis-related bacteria on orthodontic mini-implants: An in vitro study. | Abdillah RAK, Budhy TI, Narmada IB, Ardani IGAW, Ramadhani NF, Sitalaksmi RM, Luthfi M, Ulfa NM, Nugraha AP, Tengku Ahmad Noor TNEB, Nugraha AP. | J Oral Biol Craniofac Res | 10.1016/j.jobcr.2024.12.017 | 2025 | | |
| Associations Between Oral Microbiota Pathogens and Elevated Depressive and Anxiety Symptoms in Men. | Kerff F, Pasco JA, Williams LJ, Jacka FN, Loughman A, Dawson SL. | Depress Anxiety | 10.1155/da/9961595 | 2025 | | |
| Anaerobes in specific infectious and noninfectious diseases: new developments. | Boyanova L, Markovska R, Yordanov D, Gergova R, Hadzhiyski P. | Anaerobe | 10.1016/j.anaerobe.2023.102714 | 2023 | | |
| The Impact of the Microbiota on the Immune Response Modulation in Colorectal Cancer. | Neagu AI, Bostan M, Ionescu VA, Gheorghe G, Hotnog CM, Roman V, Mihaila M, Stoica SI, Diaconu CC, Diaconu CC, Ruta SM, Bleotu C. | Biomolecules | 10.3390/biom15071005 | 2025 | | |
| Impact of gut microbiome on outcomes following endoscopic interventions in gastrointestinal disease. | Agrawal H, Agarwal N, Gupta N. | World J Gastrointest Endosc | 10.4253/wjge.v17.i11.110207 | 2025 | | |
| Photodynamic therapy in non-surgical treatment of periodontitis. | Maj A, Kusiak A, Garbacz K, Cichonska D, Swietlik D. | Sci Rep | 10.1038/s41598-025-89563-3 | 2025 | | |
| Investigating the Association Between Fusobacterium nucleatum and Oral Squamous Cell Carcinoma: A Pilot Case-Control Study on Tissue Samples. | Kaliamoorthy S, Priya Sayeeram S, SundarRaj S, Balakrishnan J, Nagarajan M, Samidorai A. | Cureus | 10.7759/cureus.47238 | 2023 | | |
| Oral Bacterial Contributions to Gingival Carcinogenesis and Progression. | Okuyama K, Yanamoto S. | Cancer Prev Res (Phila) | 10.1158/1940-6207.capr-22-0511 | 2023 | | |
| Development of Surgical Site Infection One Year After Thyroplasty With Arytenoid Adduction. | Simmons E, Lao WP, Punjabi N, Krishna P. | Clin Case Rep | 10.1002/ccr3.9666 | 2024 | | |
| Antimicrobial activity of piperacillin/tazobactam against key peri-implant pathogens: an in vitro comparative study with amoxicillin-clavulanate and minocycline. | Hurtado-Celotti D, Andres-Veiga M, Madrigal Martinez-Pereda C, Meniz-Garcia C, Santos-Marino J, Martinez-Rodriguez N. | Med Oral Patol Oral Cir Bucal | 10.4317/medoral.27797 | 2025 | | |
| Empyema caused by Fusobacterium nucleatum with squamous cell carcinoma of the lung: a case report and literature review. | Sun Y, Dong H, Zhang N, Zhao P, Qi Y, Yang X, Wang L. | Front Med (Lausanne) | 10.3389/fmed.2023.1099040 | 2023 | | |
| Microbiological Study of Periodontal Disease in Populations with HIV: a Systematic Review and Meta-Analysis. | Valian NK, Houshmand B, Ardakani MT, Mahmoudi S. | Clin Lab | 10.7754/clin.lab.2022.220738 | 2023 | | |
| Association Between Oral Dysbiosis and Alzheimer's Disease: A Systematic Review. | Martinez-Martinez V, Rodriguez-Lozano FJ, Pecci-Lloret MP, Perez-Guzman N. | J Clin Med | 10.3390/jcm14103415 | 2025 | | |
| Metabolism | Multi-omic profiling reveals associations between the gut microbiome, host genome and transcriptome in patients with colorectal cancer. | Zou S, Yang C, Zhang J, Zhong D, Meng M, Zhang L, Chen H, Fang L. | J Transl Med | 10.1186/s12967-024-04984-4 | 2024 | |
| In situ-activated photothermal nanoplatform for on-demand NO gas delivery and enhanced colorectal cancer treatment. | Xin Y, Yu Y, Su M, Li X, Elsabahy M, Gao H. | J Control Release | 10.1016/j.jconrel.2023.05.034 | 2023 | | |
| The Influence of Dental Status and Blood Parameters Characterizing Endogenous Intoxication on the Timing of Childbirth. | Hakobyan M, Manrikyan G, Markaryan M, Vardanyan I, Manrikyan M. | Medicina (Kaunas) | 10.3390/medicina60071176 | 2024 | | |
| Exploring the potential causal association between oral microbiota and heart failure using Mendelian randomization in an East Asian population. | Peng S, Li K, Liu P, Wang L, Man Y. | Medicine (Baltimore) | 10.1097/md.0000000000044711 | 2025 | | |
| Effects ofBifidobacterium lactisHN019 andLactobacillus acidophilusNCFM on volatile sulfur compounds produced by oral anaerobes. | Huang P, Yuan S, Xu X, Peng X. | J Breath Res | 10.1088/1752-7163/ac9db4 | 2022 | | |
| Calcium phosphate cement with minocycline hydrochloride-loaded gelatine microspheres for peri-implantitis treatment. | Liu N, Huang S, Guo F, Wang D, Zuo Y, Li F, Liu C. | J Dent | 10.1016/j.jdent.2023.104624 | 2023 | | |
| Influence of nitrate-containing arugula juice on nitrate-reducing oral bacteria and periodontopathogens in smokers' biofilm. | Bachtiar BM, Rieuwpassa IE, Susilowati H, Indrawati R, Theodorea CF, Fath T, Bachtiar EW. | Front Dent Med | 10.3389/fdmed.2025.1545479 | 2025 | | |
| The Knowledge Gap in Gut Microbiome Characterization in Early-Onset Colorectal Cancer Patients: A Systematic Scoping Review. | Gomes de Sousa R, Guerreiro CS, Santos I, Cravo M. | Cancers (Basel) | 10.3390/cancers17111863 | 2025 | | |
| Fusobacterium nucleatum load in MSI colorectal cancer subtypes. | Ono T, Yamaguchi T, Takao M, Kojika E, Iijima T, Horiguchi SI. | Int J Clin Oncol | 10.1007/s10147-022-02218-5 | 2022 | | |
| Advances in intestinal flora for the development, diagnosis and treatment of CRC. | Hu R, Qiu Y, Liu DA, Chen S, Chen K, Xu Y, Yuan J, Zhang X, Li X. | Front Microbiol | 10.3389/fmicb.2025.1495274 | 2025 | | |
| Fusobacterium nucleatum as an oral bacteria promotes the carcinogenesis of laryngeal cancer via upregulating YWHAZ. | Ren Y, Ye J, Shi L, Le K, Wang Y. | J Oral Microbiol | 10.1080/20002297.2024.2442245 | 2025 | | |
| Neutrophil-Mimicking Nanomedicine Eliminates Tumor Intracellular Bacteria and Enhances Chemotherapy on Liver Metastasis of Colorectal Cancer. | Niu Y, Zhao X, Li Y, Ma X, Yang W, Ma J, Li W, Yuan W. | Adv Sci (Weinh) | 10.1002/advs.202504188 | 2025 | | |
| Oral-gut microbial transmission promotes diabetic coronary heart disease. | Li Y, Liu Y, Cui J, Zhu M, Wang W, Chen K, Huang L, Liu Y. | Cardiovasc Diabetol | 10.1186/s12933-024-02217-y | 2024 | | |
| Pathogenicity | Nanoparticles as Strategies for Modulating the Host's Response in Periodontitis Treatment. | Mlachkova A, Dosseva-Panova V, Maynalovska H, Pashova-Tasseva Z. | Nanomaterials (Basel) | 10.3390/nano15070476 | 2025 | |
| Genitourinary microbiomes and prostate cancer: a systematic review and meta-analysis of tumorigeneses and cancer characteristics. | Parizi MK, Matsukawa A, Alimohammadi A, Klemm J, Tsuboi I, Fazekas T, Laukhtina E, Chiujdea S, Karakiewicz PI, Shariat SF. | Cent European J Urol | 10.5173/ceju.2024.80 | 2024 | | |
| Brain Abscess Caused by Streptococcus intermedius and Aggregatibacter aphrophilus Secondary to Exfoliation of a Deciduous Tooth in a Previously Healthy Child: A Case Report. | Noda K, Miura H, Kozawa K, Muto J, Yoshikawa T. | Cureus | 10.7759/cureus.80591 | 2025 | | |
| In vitro comparison of antioxidant, cytotoxic, and antibacterial (against Aggregatibacter actinomycetemcomitans) effects of Citrus reticulata, Olea europaea extracts, and essential oils. | Vahabi S, Torshabi M, Mirsharif SZ. | Dent Res J (Isfahan) | 10.4103/drj.drj_110_24 | 2025 | | |
| Involvement of propionate, citrulline, homoserine, and succinate in oral microbiome metabolite-driven periodontal disease progression. | Ishihara C, Sako M, Tsutsumi K, Fujii N, Hashimoto D, Sato A, Ichiba Y, Chikazawa T, Kakizawa Y, Nishinaga E, Uchiyama A. | Sci Rep | 10.1038/s41598-025-91105-w | 2025 | | |
| Revisiting Socransky's Complexes: A Review Suggesting Updated New Bacterial Clusters (GF-MoR Complexes) for Periodontal and Peri-Implant Diseases and Conditions. | Fernandes GVO, Mosley GA, Ross W, Dagher A, Martins BGDS, Fernandes JCH. | Microorganisms | 10.3390/microorganisms12112214 | 2024 | | |
| Bioactive glass air-abrasion promotes healing around contaminated implant surfaces surrounded by circumferential bone defects: An experimental study in the rat. | Abushahba F, Areid N, Gursoy M, Willberg J, Laine V, Yatkin E, Hupa L, Narhi TO. | Clin Implant Dent Relat Res | 10.1111/cid.13172 | 2023 | | |
| A Comprehensive Review of Antibiotic Resistance in the Oral Microbiota: Mechanisms, Drivers, and Emerging Therapeutic Strategies | Kulis E, Cvitkovic I, Pavlovic N, Kumric M, Rusic D, Bozic J. | Antibiotics (Basel) | 2025 | | ||
| Pylephlebitis Caused by Bacillus subtilis and Fusobacterium nucleatum. | Ochi T, Oh K, Konishi H. | Intern Med | 10.2169/internalmedicine.2150-23 | 2024 | | |
| Periodontitis and progression of gastrointestinal cancer: current knowledge and future perspective. | Nasiri K, Amiri Moghaddam M, Etajuri EA, Badkoobeh A, Tavakol O, Rafinejad M, Forutan Mirhosseini A, Fathi A. | Clin Transl Oncol | 10.1007/s12094-023-03162-0 | 2023 | | |
| Distribution and Characteristics of Oral Pathogens According to Blood Glucose Levels in South Korean Health Examinees. | Choi YJ, Park J, Shin MG, Jung BK, Shin H, Cho S, Cho HI, Nah EH. | Int J Mol Sci | 10.3390/ijms26062638 | 2025 | | |
| Influence of maternal oral microbiome on newborn oral microbiome in healthy pregnancies. | Russo M, Calevo MG, D'Alessandro G, Tantari M, Migliorati M, Piccardo I, Perucchin PP, Arioni C. | Ital J Pediatr | 10.1186/s13052-023-01520-w | 2023 | | |
| Gut microbiota as a hidden modulator of chemotherapy: implications for colorectal cancer treatment. | Sadeghloo Z, Sadeghi A. | Discov Oncol | 10.1007/s12672-025-03574-0 | 2025 | | |
| Targeting the Tumor Microbiota in Cancer Therapy Basing on Nanomaterials | Niu Y, Feng J, Ma J, Xiao T, Yuan W. | Exploration (Beijing) | 2025 | | ||
| Fusobacterium Nucleatum Is a Risk Factor for Metastatic Colorectal Cancer. | Chen WD, Zhang X, Zhang YP, Yue CB, Wang YL, Pan HW, Zhang YL, Liu H, Zhang Y. | Curr Med Sci | 10.1007/s11596-022-2597-1 | 2022 | | |
| Septic thrombophlebitis of portal and splenic vein secondary to Fusobacterium nucleatum: A case report of an abdominal variant of lemierre syndrome. | Pandey S, Rayapureddy AK, Manvar K, Edara S, Boddu G, Thakur A, Jaswani V. | Medicine (Baltimore) | 10.1097/md.0000000000035622 | 2023 | | |
| Detection and treatment of biofilm-induced periodontitis by histidine-doped FeSN nanozyme with ultra-high peroxidase-like activity. | Shen B, Yang L, Xu H, Zhang Y, Ming D, Zhu L, Wang Y, Jiang L. | J Colloid Interface Sci | 10.1016/j.jcis.2023.06.188 | 2023 | | |
| Salivary Metabolites Produced by Oral Microbes in Oral Diseases and Oral Squamous Cell Carcinoma: A Review. | Kashyap B, Kullaa A. | Metabolites | 10.3390/metabo14050277 | 2024 | | |
| Middle meatus microbiome in patients with eosinophilic chronic rhinosinusitis in a Japanese population. | Kidoguchi M, Imoto Y, Noguchi E, Nakamura T, Morii W, Adachi N, Ii R, Koyama K, Aoki S, Miyashita K, Hosokawa Y, Omura K, Tanaka Y, Tanaka K, Hida Y, Ninomiya T, Kato Y, Sakashita M, Takabayashi T, Fujieda S. | J Allergy Clin Immunol | 10.1016/j.jaci.2023.06.029 | 2023 | | |
| Effects of Pregnancy on Oral Health: A Narrative Review. | Varsha A, Garg A, Thakur R. | Cureus | 10.7759/cureus.94929 | 2025 | | |
| Transcriptome | Comprehensive analysis of transcriptome and microbiome in colorectal cancer with synchronous polyp patients. | Wang Y, Liu Y, Liu X, Xu P, Luo M, Huang A, Su Z. | Front Cell Infect Microbiol | 10.3389/fcimb.2025.1547057 | 2025 | |
| The bibliometric analysis of research on traditional Chinese medicine regulating gut microbiota for cancer treatment from 2014 to 2024 | Lei Y, Shan Y, Zhou D, Chen C. | Hereditas | 2025 | | ||
| Papillon-Lefèvre Syndrome: Case Report of Two Sisters. | El-Missioui A, Benkarroum FZ, Ramdi H. | Int J Clin Pediatr Dent | 10.5005/jp-journals-10005-3174 | 2025 | | |
| The Effect of Subgingival Curcumin Gel With and Without Photodynamic Therapy as Adjunctive Periodontal Treatment in Type 2 Diabetes Mellitus Patients: A Split-Mouth Clinical and Microbiological Study. | Hormdee D, Tarawadee N, Rinsathorn W, Puasiri S, Suwannarong W. | Int J Dent | 10.1155/ijod/2575672 | 2025 | | |
| Spontaneous brain abscess formation: challenge of a shifting pathogen spectrum over the last 21 years - a single center experience. | Kraus LM, Overstijns M, Rahal AE, Behringer S, Buttler KJ, Andereggen L, Beck J, Schnell O, Hornuss D, Wagner D, Cipriani D. | Acta Neurochir (Wien) | 10.1007/s00701-024-06349-8 | 2024 | | |
| Fusobacterium nucleatum impairs DNA mismatch repair and stability in patients with squamous cell carcinoma of the head and neck. | Hsueh CY, Lau HC, Huang Q, Gong H, Sun J, Cao P, Hu C, Zhang M, Tao L, Zhou L. | Cancer | 10.1002/cncr.34338 | 2022 | | |
| Odontogenic brain abscess caused by Porphyromonas gingivalis and Streptococcus constellatus: a case report and review article. | Sun S, He R, Chen S, Ren J, Ma X, Yang J. | J Oral Microbiol | 10.1080/20002297.2025.2485197 | 2025 | | |
| The Effects of Electrolytic Technology Toothbrush Application on the Clinical Parameters and Bacteria Associated with Periodontal Disease in Dogs. | Zdravkovic N, Stanisavljevic N, Malesevic M, Vukotic G, Stevanovic T, Bosnjak I, Ninkovic M. | Animals (Basel) | 10.3390/ani14213067 | 2024 | | |
| Effect of the Progression of Fusobacterium nucleatum-induced Apical Periodontitis on the Gut Microbiota. | Haraga H, Sato T, Watanabe K, Hamada N, Tani-Ishii N. | J Endod | 10.1016/j.joen.2022.04.014 | 2022 | | |
| Gymnema sylvestre as a Potential Anti-Inflammatory and Anti-Biofilm Agent Against Anaerobic Infections: An In Vitro Study. | Miranda DG, Tome FM, Miguel MMV, Liberato SFDS, Marcucci MC, Vigerelli H, Rodrigues FP, Pacheco-Soares C, Godoi BH, Carrouel F, de Oliveira LD, Ramos LP. | Plants (Basel) | 10.3390/plants14040497 | 2025 | | |
| Antibiotic resistance in the microbiota of periodontitis patients: an update of current findings. | Ng E, Tay JRH, Boey SK, Laine ML, Ivanovski S, Seneviratne CJ. | Crit Rev Microbiol | 10.1080/1040841x.2023.2197481 | 2024 | | |
| A gut-derived Streptococcus salivarius produces the novel nisin variant designated nisin G and inhibits Fusobacterium nucleatum in a model of the human distal colon microbiome. | Lawrence GW, Garcia-Gutierrez E, O'Mahony AK, Walsh CJ, O'Connor PM, Begley M, Guinane CM, Cotter PD. | mBio | 10.1128/mbio.01573-24 | 2025 | | |
| The redox-active Cu-FomA complex: the mode that provides coordination of CuII/CuI ions during the reduction/oxidation cycle. | Walencik PK. | Dalton Trans | 10.1039/d2dt02398a | 2022 | | |
| Fusobacterium nucleatum endocarditis: a case report and literature review. | Dhaliwal D, Bhargava R, Movahed MR. | Am J Cardiovasc Dis | 2023 | | ||
| Oral Health and Diabetic Cardiomyopathy: Mechanisms, Biomarkers, and Early Screening Approaches. | Fang J, Wu Y, Wang H, Zhang J, You L. | J Inflamm Res | 10.2147/jir.s521430 | 2025 | | |
| Intratumoral microbiota as cancer therapeutic target. | Guo C, An Q, Zhang LY, Wei XD, Xu J, Yu JY, Wu GJ, Ma J. | Aging Med (Milton) | 10.1002/agm2.12359 | 2024 | | |
| Phage therapy in gut microbiome. | Chen X, Mendes BG, Alves BS, Duan Y. | Prog Mol Biol Transl Sci | 10.1016/bs.pmbts.2023.04.005 | 2023 | | |
| Intestinal and esophageal microbiota in esophageal cancer development and treatment. | Baba Y, Tajima K, Yoshimura K. | Gut Microbes | 10.1080/19490976.2025.2505118 | 2025 | | |
| Influence of Citrobacter freundii on NINJ2 Expression and Oxaliplatin Resistance in Colorectal Cancer. | Ueta R, Imai H, Saijo K, Kawamura Y, Kodera S, Ishioka C. | Cancer Med | 10.1002/cam4.70940 | 2025 | | |
| Microbiological mechanisms of oral mucosal disease: oral-intestinal crosstalk and probiotic therapy. | Zhou Q, Liu P, Chen M, He H, Xu M, Xu Q, Yu J, Deng Y, Yan J, Wen Y. | Front Oral Health | 10.3389/froh.2025.1485028 | 2025 | | |
| Graphene Coated Ti-6Al-4V Exhibits Antibacterial and Antifungal Properties Against Oral Pathogens. | Wang X, Zhao W, Zhao C, Zhang W, Yan Z. | J Prosthodont | 10.1111/jopr.13595 | 2023 | | |
| Derivation and validation of lifestyle-based and microbiota-based models for colorectal adenoma risk evaluation and self-prediction. | Zhou YL, Deng JW, Liu ZH, Ma XY, Zhu CQ, Xie YH, Zhou CB, Fang JY. | BMJ Open Gastroenterol | 10.1136/bmjgast-2024-001597 | 2025 | | |
| Presence of Fusobacterium nucleatum in relation to patient survival and an acidic environment in oesophagogastric junction and gastric cancers. | Hara Y, Baba Y, Oda E, Harada K, Yamashita K, Toihata T, Kosumi K, Iwatsuki M, Miyamoto Y, Tsutsuki H, Gan Q, Waters RE, Komohara Y, Sawa T, Ajani JA, Baba H. | Br J Cancer | 10.1038/s41416-024-02753-0 | 2024 | | |
| Genetics | The Effect of Limosilactobacillus fermentum MG4717 on Oral Health and Biosafety. | Park JY, Lee JY, Kim Y, Kim BK, Choi SI. | Microorganisms | 10.3390/microorganisms13071600 | 2025 | |
| Structure of the lipopolysaccharide O-antigens from Fusobacterium nucleatum strains SB-106CP and HM-992 and immunological comparison to the O-antigen of strain 12230. | Vinogradov E, Michael FS, Cairns C, Cox AD. | Carbohydr Res | 10.1016/j.carres.2022.108576 | 2022 | | |
| Suppressive Effects of Kouboku on Methyl Mercaptan Production and Biofilm Formation in Porphyromonas gingivalis. | Taniguchi Y, Ouhara K, Sato Y, Shoji M, Hou Y, Zhai R, Fujimori R, Kuwahara N, Tamura T, Matsuda S, Mizuno N. | Mol Oral Microbiol | 10.1111/omi.12493 | 2025 | | |
| Point-of-care Ultrasound Identification of Hepatic Abscess in the Emergency Department. | Blomquist M, Brinkerhoff T, Weech D, Choi H. | Clin Pract Cases Emerg Med | 10.5811/cpcem.1299 | 2023 | | |
| Lemierre's Syndrome Caused by Streptococcus pneumoniae in a Patient with Carbimazole-Induced Severe Neutropenia. | Lodha N, Vihari N, Midha NK, Sethi TK, Garg P, Tak V. | Kans J Med | 10.17161/kjm.vol17.21217 | 2024 | | |
| Bidirectional regulation of the gut microbiome-immune axis in the immune microenvironment of colorectal cancer and targeted interventions. | Liu XX, Yang B, Tang DX. | World J Gastrointest Oncol | 10.4251/wjgo.v17.i10.109503 | 2025 | | |
| Evaluation of targeted next-generation sequencing for microbiological diagnosis of acute lower respiratory infection. | Yang F, Jiang L, Cao Q, Yi M, Zhao Q. | Front Microbiol | 10.3389/fmicb.2025.1615965 | 2025 | | |
| Long non-coding RNA EVADR induced by Fusobacterium nucleatum infection promotes colorectal cancer metastasis. | Lu X, Xu Q, Tong Y, Zhang Z, Dun G, Feng Y, Tang J, Han D, Mao Y, Deng L, He X, Li Q, Xiang Y, Wang F, Zeng D, Tang B, Mao X. | Cell Rep | 10.1016/j.celrep.2022.111127 | 2022 | | |
| Fecal Microbiota Transplantation Induces Sustained Gut Microbiome Changes in Pediatric Ulcerative Colitis: A Combined Randomized and Open-Label Study. | Le J, Hakimjavadi H, Parsana R, Chamala S, Michail S. | Gastro Hep Adv | 10.1016/j.gastha.2025.100741 | 2025 | | |
| Genetics | Microbiome and fragmentation pattern of blood cell-free DNA and fecal metagenome enhance colorectal cancer micro-dysbiosis and diagnosis analysis: a proof-of-concept study. | Zhou Z, Ma Y, Zhang D, Ji R, Wang Y, Zhao J, Ma C, Zhu H, Shen H, Jiang X, Niu Y, Lu J, Zhang B, Tu L, Zhang H, Ma X, Chen P. | mSystems | 10.1128/msystems.00276-25 | 2025 | |
| Oral leukoplakia: still an enigmatic disorder. | Aguirre-Urizar JM. | Med Oral Patol Oral Cir Bucal | 10.4317/medoral.27214 | 2025 | | |
| Phylogeny | Integrative multi-omics analysis of the microbiome and metabolome in bronchoalveolar lavage fluid from patients with early-stage lung cancer. | Xie J, Zhu N, Xu W. | Front Cell Infect Microbiol | 10.3389/fcimb.2025.1513270 | 2025 | |
| Effect of curcumin-loaded photoactivatable polymeric nanoparticle on peri-implantitis-related biofilm. | Tonon CC, Panariello B, Chorilli M, Spolidorio DMP, Duarte S. | Photodiagnosis Photodyn Ther | 10.1016/j.pdpdt.2022.103150 | 2022 | | |
| Fusobacterium Nucleatum Aggravates Intestinal Barrier Impairment and Colitis Through IL-8 Induced Neutrophil Chemotaxis by Activating Epithelial Cells. | Wang Z, Li B, Bao L, Chen Y, Yang J, Xu F, Shi S, Chen W, Wang B, Liu Y. | J Inflamm Res | 10.2147/jir.s470376 | 2024 | | |
| A scientometric study on research trends and characteristics of halitosis. | Liu X, Zhang Y, Liu Q, Hou C, Xu L. | J Dent Sci | 10.1016/j.jds.2025.03.020 | 2025 | | |
| Clinical Characteristics and Prognosis of Patients with Severe Pneumonia with Neurological Dysfunction: A Regional Multicenter Retrospective Study in Mainland China | Zhu Y, Jia Y, Zhang C, Li H, Ding P, Huang L, Wang G, Cai H, Yu W. | Infect Drug Resist | 2025 | | ||
| Electrochemical decontamination of titanium dental implants. An in vitro biofilm model study. | Virto L, Odeh V, Garcia-Quismondo E, Herrera D, Palma J, Tamimi F, Sanz M. | Clin Oral Implants Res | 10.1111/clr.14055 | 2023 | | |
| Genetics | Linking periodontitis with 20 cancers, emphasis on oropharyngeal cancer: a Mendelian randomization analysis. | Xiong J, Liu H, Li C, Li Y, Feng J. | Sci Rep | 10.1038/s41598-024-63447-4 | 2024 | |
| Comparison of two primer-probe sets of Fusobacterium nucleatum using droplet digital polymerase chain reaction for the detection of colorectal neoplasia from faecal samples. | Yamaoka Y, Sasai M, Suehiro Y, Hashimoto S, Goto A, Yamamoto N, Suzuki N, Higaki S, Fujii I, Suzuki C, Matsumoto T, Hoshida T, Koga M, Tsutsumi T, Lim LA, Matsubara Y, Tomochika S, Yoshida S, Hazama S, Yotsuyanagi H, Nagano H, Sakaida I, Takami T, Yamasaki T. | Ann Clin Biochem | 10.1177/00045632221115559 | 2022 | | |
| Unraveling a Unique Encounter of Fusobacterium nucleatum With Empyema: A Case Report and Review of Literature. | Sanivarapu RR, Rajamreddy RS, Kosaraju A. | Cureus | 10.7759/cureus.42488 | 2023 | | |
| Pathogenicity | Oral Fusobacterium nucleatum exacerbates ulcerative colitis via the oral-gut axis: mechanisms and therapeutic implications. | Zheng Z, Jin W, Guo W, Jin Z, Zuo Y. | Front Cell Infect Microbiol | 10.3389/fcimb.2025.1564169 | 2025 | |
| Oral microbial signatures underlying recurrence via PI3K/AKT/mTOR pathway modulation in oral squamous cell carcinoma. | Kwack DW, Praveen Z, Kim YH, Yoo CW, Ko JH, Youn SM, Park JY, Lee JH, Choi SW, Kim MK. | J Oral Microbiol | 10.1080/20002297.2025.2560020 | 2025 | | |
| Bacterial Extracellular Vesicles in Oncology: Molecular Mechanisms and Future Clinical Applications. | Bhanu P, Godwin AK, Umar S, Mahoney DE. | Cancers (Basel) | 10.3390/cancers17111774 | 2025 | | |
| Auto-DRRAFTER: Automated RNA Modeling Based on Cryo-EM Density. | Ma H, Pham P, Luo B, Rangan R, Kappel K, Su Z, Das R. | Methods Mol Biol | 10.1007/978-1-0716-2687-0_13 | 2023 | | |
| Expression of Bacillus in colorectal tissues is associated with improved cetuximab therapy for patients with metastatic colorectal cancer. | Hsu HC, Chung HY, You JF, Lee YS, Chang JS, Hou HH, Wang CW. | Transl Oncol | 10.1016/j.tranon.2025.102575 | 2025 | | |
| Is systemic inflammation a missing link between oral microbiome and oral squamous cell carcinoma? Results from multi-omics integration analyses. | Yan L, He B, Deng Q, Qiu Y, Lin L, Shi B, Wang J, Chen F. | J Oral Microbiol | 10.1080/20002297.2025.2574326 | 2025 | | |
| Efficacy of antimicrobial photodynamic therapy on the tongue surface in the management of halitosis - A real-time polymerase chain reaction analysis. | Patil P, Patil L, Triveni MG, Usha GV, Shah R, Kumar ABT. | Photodiagnosis Photodyn Ther | 10.1016/j.pdpdt.2022.102989 | 2022 | | |
| Antimicrobial management of dental infections: Updated review. | Abdullah FM, Hatim QY, Oraibi AI, Alsafar TH, Alsandook TA, Lutfi W, Al-Hussaniy HA. | Medicine (Baltimore) | 10.1097/md.0000000000038630 | 2024 | | |
| Expression of miRNAs in the Relationship Between Periodontitis and Cardiovascular Diseases: A Systematic Review. | Guerrero-Sabater M, Cosin-Villanueva M, Alminana-Pastor P, Lopez-Roldan A. | Noncoding RNA | 10.3390/ncrna11030037 | 2025 | | |
| Pathogenicity | The bacterial microbiome and cancer: development, diagnosis, treatment, and future directions. | Qasem HH, El-Sayed WM. | Clin Exp Med | 10.1007/s10238-024-01523-9 | 2024 | |
| Effects of Antiseptic Formulations on Oral Microbiota and Related Systemic Diseases: A Scoping Review | Angjelova A, Jovanova E, Polizzi A, Leonardi R, Isola G. | Antibiotics (Basel) | 2025 | | ||
| Protease-Loaded CuS Nanoparticles with Synergistic Photothermal/Dynamic Therapy against F. nucleatum-Induced Periodontitis. | Gao P, Li G, Wang Z, Zhang H, Shan Y, Yuan X, Shi Q, Dou X, Zhou Q, Xu Q. | ACS Appl Mater Interfaces | 10.1021/acsami.3c04534 | 2023 | | |
| Comparison of Microbial Composition of Natural Teeth and Implants by 16S rRNA Gene Sequencing. | Rajasekar A, Balu P, Kumar SR, Varghese SS. | J Long Term Eff Med Implants | 10.1615/jlongtermeffmedimplants.2022044519 | 2023 | | |
| Anomalous Left Superior Vena Cava Predisposing to Recurrent Brain Abscesses: A Case Report and Review of the Literature. | Shaik A, Joseph K, Abo Kasem R, Downes A, Janjua MB. | Cureus | 10.7759/cureus.62329 | 2024 | | |
| Cardiotonic Steroids as a Potential Novel Approach for Immunomodulation in Inflammatory Bowel Disease. | Cavalcante-Silva LHA, Sales-Neto JM, Soares MM, Ferreira DA, Medeiros ABA, Rodrigues-Mascarenhas S. | J Clin Med | 10.3390/jcm14124132 | 2025 | | |
| Rectal Cancer Presenting with Absceding Infection Due to Fusobacterium nucleatum. | Zundler S, Mardin C, Bertz S, Vitali F, Strauss R, Furst J, Neurath MF, Strobel D. | Pathogens | 10.3390/pathogens11101113 | 2022 | | |
| Oral Microbiota and Pharyngeal-Laryngeal Cancer Risk: Evidence from Mendelian Randomization in East Asian Populations. | Fu J. | Pol J Microbiol | 10.33073/pjm-2025-029 | 2025 | | |
| Photosensitive small intestinal submucosal hydrogels loaded with the KR-12-a5 peptide promote periodontal osteogenesis and antimicrobial activity. | Ma S, Yan Q, Li L, Ni Y, Chen K, Xu B, Li Y, Cui M, Liu F, Chang K, Kou B, Li R. | J Nanobiotechnology | 10.1186/s12951-025-03601-w | 2025 | | |
| Pathogenicity | Gut microbiota alterations and their association with tumorigenic pathways in colorectal cancer: insights from a pooled analysis of 109 microbiome datasets. | Haque S, Bantun F, Jalal NA, Faidah H, Babalghith AO, Alobaidy MA, Aldairi AF, Ahmad F. | Gut Pathog | 10.1186/s13099-025-00712-5 | 2025 | |
| Oral and throat microbiological changes after orthodontic debonding. | Lucchese A, Nocini R, Lo Giudice A, Asperio P, Guglietta F, Carenzi L, Bertacci A, Donadello D, Farronato M, Maspero C, Zerman N. | New Microbiol | 2022 | | ||
| Dental problems and oral microbiome alterations in ulcerative colitis. | Kucharski R, Sobocki BK, Stachowska E, Bulman N, Kalinowski L, Kazmierczak-Siedlecka K. | Front Immunol | 10.3389/fimmu.2025.1502605 | 2025 | | |
| Pathogenicity | The association between Fusobacterium nucleatum and cancer colorectal: A systematic review and meta-analysis. | Villar-Ortega P, Exposito-Ruiz M, Gutierrez-Soto M, Ruiz-Cabello Jimenez M, Navarro-Mari JM, Gutierrez-Fernandez J. | Enferm Infecc Microbiol Clin (Engl Ed) | 10.1016/j.eimce.2022.02.007 | 2022 | |
| Pathogenicity | Periodontitis associated with Porphyromonas gingivalis infection is a risk factor for infertility through uterine hypertrophy. | Kamei-Nagata C, Omori K, Sako H, Sakaida K, Nakayama MA, Ohara T, Mandai H, Kubota-Takamori M, Kiyama F, Ishii T, Hirai K, Ikeda A, Takeuchi-Hatanaka K, Shinoda-Ito Y, Tai-Tokuzen M, Sakamoto A, Kiyokawa M, Yamanishi T, Oda T, Takigawa M, Yamamoto T, Miyake T, Takashiba S. | Sci Rep | 10.1038/s41598-025-18992-x | 2025 | |
| Prospective study on diagnostic efficacy of targeted NGS vs. traditional testing for respiratory infections in myelosuppressed hematology patients. | Li C, Wu J, Feng Y. | Front Med (Lausanne) | 10.3389/fmed.2025.1488652 | 2025 | | |
| Pathogenicity | Microsatellite Instability in the Tumor Microenvironment: The Role of Inflammation and the Microbiome. | Vargas-Castellanos E, Rincon-Riveros A. | Cancer Med | 10.1002/cam4.70603 | 2025 | |
| Sternoclavicular Septic Arthritis Caused by Parvimonas micra and Fusobacterium nucleatum Infection with Intra-articular Corticosteroid Administration. | Saishoji Y, Mori K, Izumi Y. | Intern Med | 10.2169/internalmedicine.1563-23 | 2024 | | |
| Comparative Evaluation of Subgingivally Delivered Tetracycline Fibers and Aloe Vera Gel as an Adjunct to Scaling and Root Planing in Treatment of Chronic Periodontitis: A Randomized Controlled Clinical Trial. | Thakuria A, Agarwal S, Madan E, Sharma K, Fatima Z. | J Pharm Bioallied Sci | 10.4103/jpbs.jpbs_700_24 | 2024 | | |
| Adrenaline in pulp capping treatment of reversible pulpitis. | Yang SY, Wang JZ, Fan H, Chen M. | World J Clin Cases | 10.12998/wjcc.v12.i22.5024 | 2024 | | |
| Limited Diagnostic Value of Blood Cultures in Patients with Soft Tissue Infections Transferred to a Quaternary Care Center. | Ghneim MH, Schrank GM, Teeter W, Andersen B, Brown A, Tran QK. | Bioengineering (Basel) | 10.3390/bioengineering12060609 | 2025 | | |
| Phylogeny | Quantitative profiling of bacterial communities via full length 16S rRNA gene sequencing with internal controls: optimization and validation across diverse human microbiomes. | Valido E, Bertolo A, Stoyanov J. | BMC Microbiol | 10.1186/s12866-025-04399-1 | 2025 | |
| Antibacterial activity of barbatimão (Stryphnodendron adstringens) against periodontopathogens and cytotoxic effects on fibroblasts. | de Melo RN, de Goes VFF, Canelli AP, de Aro AA, Moreira BO, Correia JR, Catirse ABCEB, Dos Reis AC, Costa SM, de Godoi APT. | Lett Appl Microbiol | 10.1093/lambio/ovad054 | 2023 | | |
| Unveiling Therapeutic Potential: Targeting Fusobacterium nucleatum's Lipopolysaccharide Biosynthesis for Endodontic Infections-An In Silico Screening Study. | Boreak N, Alrajab EA, Nahari RA, Najmi LE, Masmali MA, Ghawi AA, Al Moaleem MM, Alhazmi MY, Maqbul AA. | Int J Mol Sci | 10.3390/ijms25084239 | 2024 | | |
| Pathogenicity | The root canal microbiome diversity and function. A whole-metagenome shotgun analysis. | Ordinola-Zapata R, Costalonga M, Dietz M, Lima BP, Staley C. | Int Endod J | 10.1111/iej.13911 | 2024 | |
| Enzymology | Statins and oral biofilm: Simvastatin as a promising drug to control periodontal dysbiosis. | Parolina de Carvalho RD, de Andrade Moreno J, Roque SM, Chan DCH, Torrez WB, Stipp RN, Bueno-Silva B, de Lima PO, Cogo-Muller K. | Oral Dis | 10.1111/odi.14446 | 2024 | |
| Modulation of gut microbiota in targeted cancer therapy: insights on the EGFR/VEGF/KRAS pathways. | Gong L, Yang S, Huang J, Li Y. | Cancer Biol Med | 10.20892/j.issn.2095-3941.2024.0320 | 2024 | | |
| Impact of toothpaste use on the subgingival microbiome: a pilot randomized clinical trial. | Iniesta M, Vasconcelos V, Laciar F, Matesanz P, Sanz M, Herrera D. | BMC Oral Health | 10.1186/s12903-025-06159-z | 2025 | | |
| HPV Infection and Oral Microbiota: Interactions and Future Implications. | Xia Q, Pierson S. | Int J Mol Sci | 10.3390/ijms26041424 | 2025 | | |
| Antibacterial effect of a gingival patch containing nano-emulsion of red dragon fruit peel extract on Porphyromonas gingivalis, Aggregatibacter actinomycetemcomitans, and Fusobacterium nucleatum assessed in vitro. | Diyatri I, Juliastuti WS, Ridwan RD, Ananda GC, Waskita FA, Juliana NV, Khansa SP, Pratiwi RT, Putri CR. | J Oral Biol Craniofac Res | 10.1016/j.jobcr.2023.03.011 | 2023 | | |
| Targeting Fusobacterium nucleatum in colorectal cancer: therapeutic strategies and future directions. | Kowsarkhizi AS, Yousefi B, Rahimi A, Aliramezani A. | Infect Agent Cancer | 10.1186/s13027-025-00676-w | 2025 | | |
| Gastrointestinal Variant of Lemierre Syndrome due to Fusobacterium nucleatum: A Case Report. | Salam R, Verma A, Noeske M, Alnimer L, Sieloff EM, Piper MS. | Case Rep Gastroenterol | 10.1159/000536619 | 2024 | | |
| Lemierre's Syndrome With Multivessel Thrombosis, Right Atrial Extension, and Septic Pulmonary Emboli: An Unusual and Life-Threatening Presentation. | Al-Anbagi U, Hammouda S, Al Hariri B, Nashwan AJ, Abusriwil HM. | Cureus | 10.7759/cureus.91453 | 2025 | | |
| Idiopathic gingival fibromatosis and primary analysis of dominant bacteria in subgingival biofilm: a case report. | Zhu J, Fan X, Ding L, Song T. | J Int Med Res | 10.1177/03000605241245302 | 2024 | | |
| Gum Arabic as a potential candidate in quorum quenching and treatment of periodontal diseases. | Hashim NT, Babiker R, Rahman MM, Chaitanya NCSK, Mohammed R, Dasnadi SP, Gismalla BG. | Front Oral Health | 10.3389/froh.2024.1459254 | 2024 | | |
| Pathogenicity | The Effects of Azithromycin Modified Triple Antibiotic Paste in Resolving Periapical Inflammation. | Meng T, Wang Z, Li H, Ouyang Z, Yang C, Lian T, Zhang Y, Li H, Bao P, Liu D. | Int Dent J | 10.1016/j.identj.2025.100895 | 2025 | |
| Microbiota and Radiotherapy: Unlocking the Potential for Improved Gastrointestinal Cancer Treatment. | Vucinic D, Redzovic A, Hauser G, Mikolasevic I. | Biomedicines | 10.3390/biomedicines13020526 | 2025 | | |
| Phylogeny | Microbiota of Healthy Dental Pulp Under the Omics Loupe. | Berard A, Mauffrey F, Gaia N, Perez A, Chaabane C, Schrenzel J, Leprince JG, Bouillaguet S, Lazarevic V. | Int J Mol Sci | 10.3390/ijms26073232 | 2025 | |
| Prevalence and Phylogenetic Analysis of Fusobacterium nucleatum and Virulent Factor FadA among Ulcerative Colitis Precancerous and Colorectal Carcinoma Patients in the Iraqi Kurdish Population. | Taher HJ, Kamel FH. | Arch Razi Inst | 10.22092/ari.2022.360307.2570 | 2023 | | |
| Microbiome composition and metabolic pathways in shallow and deep periodontal pockets. | Moradi J, Berggreen E, Bunaes DF, Bolstad AI, Bertelsen RJ. | Sci Rep | 10.1038/s41598-025-97531-0 | 2025 | | |
| Lemierre's Syndrome in a 16-Year-Old Man Associated with Resolution of Marked Widespread St Elevation and a Normal Troponin Level. | Amini S, Meghjee S, Khan MR. | Eur J Case Rep Intern Med | 10.12890/2024_005062 | 2024 | | |
| Interactions of periodontal pathogens with platelets in the gingival crevicular fluid of patients with periodontitis. | Zhang J, Li W, Lu H, Lu R, Zhan Y, Meng H. | J Clin Periodontol | 10.1111/jcpe.13683 | 2022 | | |
| Antibiofilm Efficacy of Silver Nanoparticles Alone or Mixed with Calcium Hydroxide as Intracanal Medicaments: An Ex-Vivo Analysis. | AlGazlan AS, Auda SH, Balto H, Alsalleeh F. | J Endod | 10.1016/j.joen.2022.07.008 | 2022 | | |
| Incorporation of zinc into cetylpyridinium chloride mouthwash affects the composition of multispecies biofilms. | Torrez WB, Figueiredo LC, Santos TDS, Soares GM, Pingueiro JMS, Pereira da Silva HD, Malheiros Z, Stewart B, Feres M, Bueno-Silva B. | Biofouling | 10.1080/08927014.2022.2160242 | 2023 | | |
| Establishment and improvement of genetic manipulation tools for Fusobacterium nucleatum. | Guan Z, Wang H, Feng Q. | Eng Microbiol | 10.1016/j.engmic.2025.100192 | 2025 | | |
| Metabolic targeting of regulatory T cells in oral squamous cell carcinoma: new horizons in immunotherapy. | Gan M, Liu N, Li W, Chen M, Bai Z, Liu D, Liu S. | Mol Cancer | 10.1186/s12943-024-02193-7 | 2024 | | |
| Might Cu(II) binding, DNA cleavage and radical production by YadA fragments be involved in the promotion of F. nucleatum related cancers? | Stokowa-Soltys K, Kierpiec K, Wieczorek R. | Dalton Trans | 10.1039/d2dt00328g | 2022 | | |
| A study on the impact of gargling with compound Scutellaria baicalensis Georgi on oral health and microflora changes in fixed orthodontic patients: An experimental study. | Zhang P, Chen SG, Wang JT, Wang JD, Chen ZH, Lin HS. | Medicine (Baltimore) | 10.1097/md.0000000000039397 | 2024 | | |
| Microbiological Comparison of Maxillary Sinus Rinses in Non-Odontogenic and Odontogenic Sinusitis of Primarily Endodontic Origin. | Kwiatkowska MA, Guzek A, Jurkiewicz D, Patyk I, Pajda B, Rot P. | J Clin Med | 10.3390/jcm14144880 | 2025 | | |
| Comparison of the effectiveness of red ginseng herbal mouth rinse with chlorhexidine and saline in oral cancer patients: A pilot double-blinded randomized control trial. | Jeddy N, Saravanan R, Natrajan R, Sai Lakshmi LJ, Ashwath V, Singhal I. | J Oral Maxillofac Pathol | 10.4103/jomfp.jomfp_473_23 | 2023 | | |
| Demystifying the link between periodontitis and oral cancer: a systematic review integrating clinical, pre-clinical, and in vitro data. | Pigossi SC, Oliveira JA, de Medeiros MC, Soares LFF, D'Silva NJ. | Cancer Metastasis Rev | 10.1007/s10555-025-10285-z | 2025 | | |
| Characteristics and function of the gut microbiota in patients with rectal neuroendocrine tumors. | Gao Y, Zheng H, Ye M, Zhou G, Chen J, Qiang X, Bai J, Lu X, Tang Q. | J Cancer | 10.7150/jca.103297 | 2025 | | |
| Postoperative Gut Microbiota Changes after Colorectal Cancer Surgery: A Comparative Study Based on Resection Sites. | Hattori Y, Fujii T, Tochio T, Kumamoto T, Hiro J, Matsuoka H, Masumori K, Funasaka K, Ohno E, Hirooka Y, Suda K, Otsuka K. | J Anus Rectum Colon | 10.23922/jarc.2025-048 | 2025 | | |
| Enzymology | Expression, Purification, and Characterization of the Recombinant, Two-Component, Response Regulator ArlR from Fusobacterium nucleatum. | Fan R, Li Z, Shi X, Wang L, Zhang X, Dong Y, Quan C. | Appl Biochem Biotechnol | 10.1007/s12010-021-03785-5 | 2022 | |
| Antibacterial Activity of Banglene Extracted from Indonesian Ginger "Bangle" Against Porphyromonas gingivalis. | Sebe M, Senoura S, Miura K, Kobayashi W, Yano N, Yamauchi G, Harada K, Fukuyama Y, Kubo M, Murakami K. | Int J Mol Sci | 10.3390/ijms26051787 | 2025 | | |
| Oral inoculation of Fusobacterium nucleatum exacerbates ulcerative colitis via the secretion of virulence adhesin FadA. | Li D, Li Z, Wang L, Zhang Y, Ning S. | Virulence | 10.1080/21505594.2024.2399217 | 2024 | | |
| Placental colonization by Fusobacterium nucleatum is mediated by binding of the Fap2 lectin to placentally displayed Gal-GalNAc. | Parhi L, Abed J, Shhadeh A, Alon-Maimon T, Udi S, Ben-Arye SL, Tam J, Parnas O, Padler-Karavani V, Goldman-Wohl D, Yagel S, Mandelboim O, Bachrach G. | Cell Rep | 10.1016/j.celrep.2022.110537 | 2022 | | |
| B-cell cytokine responses to Porphyromonas gingivalis in patients with periodontitis and healthy controls. | Danielsen AK, Damgaard C, Massarenti L, Ostrup P, Riis Hansen P, Holmstrup P, Nielsen CH. | J Periodontol | 10.1002/jper.22-0438 | 2023 | | |
| Planktonic Growth of Pseudomonas aeruginosa around a Dual-Species Biofilm Supports the Growth of Fusobacterium nucleatum within That Biofilm. | Wang JC, Cordero J, Sun Y, Aranke M, Wolcott R, Colmer-Hamood JA, Hamood AN. | Int J Otolaryngol | 10.1155/2017/3037191 | 2017 | | |
| Replication Study: Fusobacterium nucleatum infection is prevalent in human colorectal carcinoma. | Repass J, Reproducibility Project: Cancer Biology. | Elife | 10.7554/elife.25801 | 2018 | | |
| Exploiting Conserved Quorum Sensing Signals in Streptococcus mutans and Streptococcus pneumoniae | Bernabe G, Pauletto A, Zamuner A, Cassari L, Castagliuolo I, Brun P, Dettin M. | Microorganisms | 10.3390/microorganisms10122386 | 2022 | | |
| Genetics | A Comparison of Homogenization vs. Enzymatic Lysis for Microbiome Profiling in Clinical Endoscopic Biopsy Tissue Samples. | Zhang C, Thakkar PV, Powell SE, Sharma P, Vennelaganti S, Betel D, Shah MA. | Front Microbiol | 10.3389/fmicb.2018.03246 | 2018 | |
| Quantification by qPCR of Pathobionts in Chronic Periodontitis: Development of Predictive Models of Disease Severity at Site-Specific Level. | Tomas I, Regueira-Iglesias A, Lopez M, Arias-Bujanda N, Novoa L, Balsa-Castro C, Tomas M. | Front Microbiol | 10.3389/fmicb.2017.01443 | 2017 | | |
| Comparison of serological reactions of typed Fusobacterium nucleatum strains with those of isolates from humans, canines, and a Macaca mulatta monkey. | Vincent JW, Falkler WA, Craig JA. | J Clin Microbiol | 10.1128/jcm.17.4.631-635.1983 | 1983 | | |
| Hemagglutinating activity of Fusobacterium nucleatum. | Falkler WA, Hawley CE. | Infect Immun | 10.1128/iai.15.1.230-238.1977 | 1977 | | |
| The Potential Teeth Bleaching and Halitosis Prevention Effects of Pediococcus inopinatus THK-30, a Kimchi-Derived Lactic Acid Bacterium: In Vitro Study. | Nguyen TTM, Zheng Q, Yi EJ, Bellere AD, Jin X, Kim HY, Yi TH. | J Funct Biomater | 10.3390/jfb15030064 | 2024 | | |
| Oral Probiotics, Streptococcus salivarius K12 and M18, Suppress the Release of Volatile Sulfur Compounds and a Virulent Protease from Oral Bacteria: An In-Vitro Study. | Park JA, Lee GR, Lee JY, Jin BH. | Oral Health Prev Dent | 10.3290/j.ohpd.b4328987 | 2023 | | |
| Transcriptome | Whole-Transcriptome Sequencing Reveals Characteristics of Cancer Microbiome in Korean Patients with GI Tract Cancer: Fusobacterium nucleatum as a Therapeutic Target. | Ahn H, Min K, Lee E, Kim H, Kim S, Kim Y, Kim G, Cho B, Jeong C, Kim Y, Park H. | Microorganisms | 10.3390/microorganisms10101896 | 2022 | |
| Prevalence and abundance of 9 periodontal pathogens in the saliva of periodontally healthy adults and patients undergoing supportive periodontal therapy. | Jung WR, Joo JY, Lee JY, Kim HJ. | J Periodontal Implant Sci | 10.5051/jpis.2006640332 | 2021 | | |
| Antiperiodontitis Effects of Siegesbeckia glabrescens In Vitro. | Bellere AD, Yu D, Oh S, Kim M, Jung J, Fang M, Zheng S, Yi TH. | Antioxidants (Basel) | 10.3390/antiox12020471 | 2023 | | |
| Development of postbiotics by bioconverting whey using Lactobacillus plantarum SMFM2017-YK1 and Limosilactobacillus fermentum SMFM2017-NK1 to alleviate periodontitis. | Choi Y, Park E, Yoon Y, Ha J. | PLoS One | 10.1371/journal.pone.0263851 | 2022 | | |
| Real-time PCR quantification of 9 periodontal pathogens in saliva samples from periodontally healthy Korean young adults. | Choi H, Kim E, Kang J, Kim HJ, Lee JY, Choi J, Joo JY. | J Periodontal Implant Sci | 10.5051/jpis.2018.48.4.261 | 2018 | | |
| Transcriptome | Utilizing Red Spotted Apollo Butterfly Transcriptome to Identify Antimicrobial Peptide Candidates against Porphyromonas gingivalis. | Lee KW, Kim JG, Veerappan K, Chung H, Natarajan S, Kim KY, Park J. | Insects | 10.3390/insects12050466 | 2021 | |
| Enzymology | Grading system for periodontitis by analyzing levels of periodontal pathogens in saliva. | Kim EH, Joo JY, Lee YJ, Koh JK, Choi JH, Shin Y, Cho J, Park E, Kang J, Lee K, Bhak J, Kim BC, Lee JY. | PLoS One | 10.1371/journal.pone.0200900 | 2018 | |
| Chalcones with potential antibacterial and antibiofilm activities against periodontopathogenic bacteria. | Satokata AAC, Souza JH, Silva LLO, Santiago MB, Ramos SB, Assis LR, Theodoro RDS, Oliveira LRE, Regasini LO, Martins CHG | Anaerobe | 10.1016/j.anaerobe.2022.102588 | 2022 | | |
| A murine periodontitis model using coaggregation between human pathogens and a predominant mouse oral commensal bacterium. | Liu M, Choi Y | J Periodontal Implant Sci | 10.5051/jpis.2104360218 | 2022 | | |
| Metabolism | Fusobacterium nucleatum Accelerates Atherosclerosis via Macrophage-Driven Aberrant Proinflammatory Response and Lipid Metabolism. | Zhou J, Liu L, Wu P, Zhao L, Wu Y | Front Microbiol | 10.3389/fmicb.2022.798685 | 2022 | |
| Transcriptome | Transcriptome analysis of Fusobacterium nucleatum reveals differential gene expression patterns in the biofilm versus planktonic cells. | Zhao T, Chen J, Liu S, Yang J, Wu J, Miao L, Sun W | Biochem Biophys Res Commun | 10.1016/j.bbrc.2021.11.075 | 2022 | |
| Pathogenicity | Disruption of Metallostasis in the Anaerobic Human Pathogen Fusobacterium nucleatum by the Zinc Ionophore PBT2. | Van Zuylen EM, Ferguson SA, Hughes A, Rennison D, Brimble MA, Cook GM | ACS Infect Dis | 10.1021/acsinfecdis.0c00887 | 2021 | |
| Comparative evaluation of apical bacterial extrusion following root canal instrumentation using different endodontic file systems: An in vitro study. | Vankayala B, Anantula K, Saladi H, Gudugunta L, Basavarajaiah JM, Yadav SS | J Conserv Dent | 10.4103/JCD.JCD_221_19 | 2020 | | |
| Pathogenicity | New Pyrimidinone-Fused 1,4-Naphthoquinone Derivatives Inhibit the Growth of Drug Resistant Oral Bacteria. | Kim K, Kim D, Lee H, Lee TH, Kim KY, Kim H | Biomedicines | 10.3390/biomedicines8060160 | 2020 | |
| Pathogenicity | Thymoquinone inhibits biofilm formation and virulence properties of periodontal bacteria. | Tantivitayakul P, Kaypetch R, Muadchiengka T | Arch Oral Biol | 10.1016/j.archoralbio.2020.104744 | 2020 | |
| Metabolism | Protocol of proceedings with Fusobacterium nucleatum and optimization of ABTS method for detection of reactive oxygen species. | Kedziora A, Lesiow MK, Krupa K, Korzeniowska-Kowal A, Adamski R, Komarnicka UK, Stokowa-Soltys K, Bugla-Ploskonska G, Jezowska-Bojczuk M | Future Microbiol | 10.2217/fmb-2019-0010 | 2020 | |
| Pleural fluid penetration of moxifloxacin and doripenem: An experimental model of empyema. | Calik M, Calik SG, Dagli M, Kesli R, Esme H | North Clin Istanb | 10.14744/nci.2019.05902 | 2019 | | |
| Phylogeny | Utilizing Whole Fusobacterium Genomes To Identify, Correct, and Characterize Potential Virulence Protein Families. | Umana A, Sanders BE, Yoo CC, Casasanta MA, Udayasuryan B, Verbridge SS, Slade DJ | J Bacteriol | 10.1128/JB.00273-19 | 2019 | |
| Antimicrobial Activity of Piper marginatum Jacq and Ilex guayusa Loes on Microorganisms Associated with Periodontal Disease. | Gamboa F, Munoz CC, Numpaque G, Sequeda-Castaneda LG, Gutierrez SJ, Tellez N | Int J Microbiol | 10.1155/2018/4147383 | 2018 | | |
| Genetics | Fusobacterium Genomics Using MinION and Illumina Sequencing Enables Genome Completion and Correction. | Todd SM, Settlage RE, Lahmers KK, Slade DJ | mSphere | 10.1128/mSphere.00269-18 | 2018 | |
| Cultivation | Two mechanisms of oral malodor inhibition by zinc ions. | Suzuki N, Nakano Y, Watanabe T, Yoneda M, Hirofuji T, Hanioka T | J Appl Oral Sci | 10.1590/1678-7757-2017-0161 | 2018 | |
| Metabolism | Structural insights into the catalytic mechanism of cysteine (hydroxyl) lyase from the hydrogen sulfide-producing oral pathogen, Fusobacterium nucleatum. | Kezuka Y, Ishida T, Yoshida Y, Nonaka T | Biochem J | 10.1042/BCJ20170838 | 2018 | |
| Enzymology | A chemical and biological toolbox for Type Vd secretion: Characterization of the phospholipase A1 autotransporter FplA from Fusobacterium nucleatum. | Casasanta MA, Yoo CC, Smith HB, Duncan AJ, Cochrane K, Varano AC, Allen-Vercoe E, Slade DJ | J Biol Chem | 10.1074/jbc.M117.819144 | 2017 | |
| Proteome | Mining the Proteome of Fusobacterium nucleatum subsp. nucleatum ATCC 25586 for Potential Therapeutics Discovery: An In Silico Approach. | Habib AM, Islam MS, Sohel M, Mazumder MH, Sikder MO, Shahik SM | Genomics Inform | 10.5808/GI.2016.14.4.255 | 2016 | |
| Pathogenicity | Strain-Specific Impact of Fusobacterium nucleatum on Neutrophil Function. | Kurgan S, Kansal S, Nguyen D, Stephens D, Koroneos Y, Hasturk H, Van Dyke TE, Kantarci A | J Periodontol | 10.1902/jop.2016.160212 | 2016 | |
| Phylogeny | Bacterial invasion into radicular dentine-an in vitro study. | Stauffacher S, Lussi A, Nietzsche S, Neuhaus KW, Eick S | Clin Oral Investig | 10.1007/s00784-016-1960-7 | 2016 | |
| Metabolism | Discovery and characterization of de novo sialic acid biosynthesis in the phylum Fusobacterium. | Lewis AL, Robinson LS, Agarwal K, Lewis WG | Glycobiology | 10.1093/glycob/cww068 | 2016 | |
| Enzymology | Copaifera reticulata oleoresin: Chemical characterization and antibacterial properties against oral pathogens. | Bardaji DK, da Silva JJ, Bianchi TC, de Souza Eugenio D, de Oliveira PF, Leandro LF, Rogez HL, Venezianni RC, Ambrosio SR, Tavares DC, Bastos JK, Martins CH | Anaerobe | 10.1016/j.anaerobe.2016.04.017 | 2016 | |
| A dual-species microbial model for studying the dynamics between oral streptococci and periodontal pathogens during biofilm development on titanium surfaces by flow cytometry. | Manti A, Ciandrini E, Campana R, Dominici S, Ciacci C, Federici S, Sisti D, Rocchi MB, Papa S, Baffone W | Res Microbiol | 10.1016/j.resmic.2016.03.004 | 2016 | | |
| Metabolism | FAD-I, a Fusobacterium nucleatum Cell Wall-Associated Diacylated Lipoprotein That Mediates Human Beta Defensin 2 Induction through Toll-Like Receptor-1/2 (TLR-1/2) and TLR-2/6. | Bhattacharyya S, Ghosh SK, Shokeen B, Eapan B, Lux R, Kiselar J, Nithianantham S, Young A, Pandiyan P, McCormick TS, Weinberg A | Infect Immun | 10.1128/IAI.01311-15 | 2016 | |
| Pathogenicity | Morphological and functional adaptations of Fusobacterium nucleatum exposed to human neutrophil Peptide-1. | Musrati AA, Fteita D, Paranko J, Kononen E, Gursoy UK | Anaerobe | 10.1016/j.anaerobe.2016.02.008 | 2016 | |
| Biotechnology | The Effect of Bamboo Leaf Extract Solution and Sodium Copper Chlorophyllin Solution on Growth and Volatile Sulfur Compounds Production of Oral Malodor Associated Some Anaerobic Periodontal Bacteria. | Majbauddin A, Kodani I, Ryoke K | Yonago Acta Med | 2015 | | |
| Pathogenicity | Identification of an antibacterial protein by functional screening of a human oral metagenomic library. | Arivaradarajan P, Warburton PJ, Paramasamy G, Nair SP, Allan E, Mullany P | FEMS Microbiol Lett | 10.1093/femsle/fnv142 | 2015 | |
| Pathogenicity | Essential oils and isolated compounds from Lippia alba leaves and flowers: antimicrobial activity and osteoclast apoptosis. | Juiz PJ, Lucchese AM, Gambari R, Piva R, Penolazzi L, Di Ciano M, Uetanabaro AP, Silva F, Avila-Campos MJ | Int J Mol Med | 10.3892/ijmm.2014.1995 | 2014 | |
| Pathogenicity | Identification and characterization of fusolisin, the Fusobacterium nucleatum autotransporter serine protease. | Doron L, Coppenhagen-Glazer S, Ibrahim Y, Eini A, Naor R, Rosen G, Bachrach G | PLoS One | 10.1371/journal.pone.0111329 | 2014 | |
| Pathogenicity | Increased proliferation and decreased membrane permeability as defense mechanisms of Fusobacterium nucleatum against human neutrophilic peptide-1. | Keskin M, Kononen E, Soderling E, Isik G, Firatli E, Uitto VJ, Gursoy UK | Anaerobe | 10.1016/j.anaerobe.2014.08.001 | 2014 | |
| Metabolism | Biomechanical loading modulates proinflammatory and bone resorptive mediators in bacterial-stimulated PDL cells. | Nogueira AV, Nokhbehsaim M, Eick S, Bourauel C, Jager A, Jepsen S, Rossa C Jr, Deschner J, Cirelli JA | Mediators Inflamm | 10.1155/2014/425421 | 2014 | |
| Pathogenicity | In vitro activity of Carvacrol against titanium-adherent oral biofilms and planktonic cultures. | Ciandrini E, Campana R, Federici S, Manti A, Battistelli M, Falcieri E, Papa S, Baffone W | Clin Oral Investig | 10.1007/s00784-013-1179-9 | 2014 | |
| Pathogenicity | Regulation of visfatin by microbial and biomechanical signals in PDL cells. | Nogueira AV, Nokhbehsaim M, Eick S, Bourauel C, Jager A, Jepsen S, Cirelli JA, Deschner J | Clin Oral Investig | 10.1007/s00784-013-0935-1 | 2013 | |
| Antibacterial Activity of Myristica fragrans against Oral Pathogens. | Shafiei Z, Shuhairi NN, Md Fazly Shah Yap N, Harry Sibungkil CA, Latip J | Evid Based Complement Alternat Med | 10.1155/2012/825362 | 2012 | | |
| Pathogenicity | Morphological, biochemical, physiological and molecular aspects of the response of Fusobacterium nucleatum exposed to subinhibitory concentrations of antimicrobials. | de Souza Filho JA, Diniz CG, Barbosa NB, de Freitas MC, Lopes Neves MS, da Gama Mazzei RN, Gameiro J, Coelho CM, da Silva VL | Anaerobe | 10.1016/j.anaerobe.2012.09.007 | 2012 | |
| Pathogenicity | Human neutrophil defensins and their effect on epithelial cells. | Gursoy UK, Kononen E, Luukkonen N, Uitto VJ | J Periodontol | 10.1902/jop.2012.120017 | 2012 | |
| In Vitro Antibacterial Activity of Galls of Quercus infectoria Olivier against Oral Pathogens. | Basri DF, Tan LS, Shafiei Z, Zin NM | Evid Based Complement Alternat Med | 10.1155/2012/632796 | 2011 | | |
| Pathogenicity | Synergy in biofilm formation between Fusobacterium nucleatum and Prevotella species. | Okuda T, Kokubu E, Kawana T, Saito A, Okuda K, Ishihara K | Anaerobe | 10.1016/j.anaerobe.2011.09.003 | 2011 | |
| Metabolism | Identification of an L-methionine gamma-lyase involved in the production of hydrogen sulfide from L-cysteine in Fusobacterium nucleatum subsp. nucleatum ATCC 25586. | Suwabe K, Yoshida Y, Nagano K, Yoshimura F | Microbiology (Reading) | 10.1099/mic.0.051813-0 | 2011 | |
| Pathogenicity | A novel organotypic dento-epithelial culture model: effect of Fusobacterium nucleatum biofilm on B-defensin-2, -3, and LL-37 expression. | Gursoy UK, Pollanen M, Kononen E, Uitto VJ | J Periodontol | 10.1902/jop.2011.110177 | 2011 | |
| Metabolism | Identification and enzymic analysis of a novel protein associated with production of hydrogen sulfide and L-serine from L-cysteine in Fusobacterium nucleatum subsp. nucleatum ATCC 25586. | Yoshida Y, Suwabe K, Nagano K, Kezuka Y, Kato H, Yoshimura F | Microbiology (Reading) | 10.1099/mic.0.048934-0 | 2011 | |
| Metabolism | Myrsinoic acid B inhibits the production of hydrogen sulfide by periodontal pathogens in vitro. | Ito S, Shimura S, Tanaka T, Yaegaki K | J Breath Res | 10.1088/1752-7155/4/2/026005 | 2010 | |
| Pathogenicity | Antimicrobial activity of sodium citrate against Streptococcus pneumoniae and several oral bacteria. | Nagaoka S, Murata S, Kimura K, Mori T, Hojo K | Lett Appl Microbiol | 10.1111/j.1472-765X.2010.02932.x | 2010 | |
| Metabolism | Fusobacterium nucleatum-associated beta-defensin inducer (FAD-I): identification, isolation, and functional evaluation. | Gupta S, Ghosh SK, Scott ME, Bainbridge B, Jiang B, Lamont RJ, McCormick TS, Weinberg A | J Biol Chem | 10.1074/jbc.M110.133140 | 2010 | |
| Metabolism | Production of indole from L-tryptophan and effects of these compounds on biofilm formation by Fusobacterium nucleatum ATCC 25586. | Sasaki-Imamura T, Yano A, Yoshida Y | Appl Environ Microbiol | 10.1128/AEM.00166-10 | 2010 | |
| Metabolism | Production of hydrogen sulfide by two enzymes associated with biosynthesis of homocysteine and lanthionine in Fusobacterium nucleatum subsp. nucleatum ATCC 25586. | Yoshida Y, Ito S, Kamo M, Kezuka Y, Tamura H, Kunimatsu K, Kato H | Microbiology (Reading) | 10.1099/mic.0.039180-0 | 2010 | |
| Pathogenicity | Mixture of periodontopathogenic bacteria influences interaction with KB cells. | Kirschbaum M, Schultze-Mosgau S, Pfister W, Eick S | Anaerobe | 10.1016/j.anaerobe.2010.03.009 | 2010 | |
| Pathogenicity | Biofilm formation enhances the oxygen tolerance and invasiveness of Fusobacterium nucleatum in an oral mucosa culture model. | Gursoy UK, Pollanen M, Kononen E, Uitto VJ | J Periodontol | 10.1902/jop.2010.090664 | 2010 | |
| Metabolism | Stimulation of epithelial cell matrix metalloproteinase (MMP-2, -9, -13) and interleukin-8 secretion by fusobacteria. | Gursoy UK, Kononen E, Uitto VJ | Oral Microbiol Immunol | 10.1111/j.1399-302X.2008.00453.x | 2008 | |
| Pathogenicity | Interactions between salivary Bifidobacterium adolescentis and other oral bacteria: in vitro coaggregation and coadhesion assays. | Nagaoka S, Hojo K, Murata S, Mori T, Ohshima T, Maeda N | FEMS Microbiol Lett | 10.1111/j.1574-6968.2008.01092.x | 2008 | |
| Enzymology | Physiological alterations of a Fusobacterium nucleatum strain exposed to oxidative stress. | da Silva VL, Diniz CG, dos Santos SG, Gomes RM, Nicoli JR, Magalhaes PP, Mendes EN, de Carvalho MA, Farias LM | J Appl Microbiol | 10.1111/j.1365-2672.2006.03236.x | 2007 | |
| Metabolism | Effects of sonicated Prevotella intermedia, Fusobacterium nucleatum and Lactobacillus casei extracts on interleukin-8 production by human dental pulp cells. | Thaweboon B, Thaweboon S, Choonharuangdej S, Suppakpatana P | Southeast Asian J Trop Med Public Health | 2006 | | |
| Metabolism | Antimicrobial actions of benzimidazoles against the oral anaerobes Fusobacterium nucleatum and Prevotella intermedia. | Sheng J, Nguyen PT, Baldeck JD, Olsson J, Marquis RE | Arch Oral Biol | 10.1016/j.archoralbio.2006.05.002 | 2006 | |
| Pathogenicity | Antimicrobial effect in vitro of chlorhexidine and calcium hydroxide impregnated gutta-percha points. | Bozza FL, Molgatini SL, Perez SB, Tejerina DP, Perez Tito RI, Kaplan AE | Acta Odontol Latinoam | 2005 | | |
| Phylogeny | Development of strain-specific PCR primers based on a DNA probe Fu12 for the identification of fusobacterium nucleatum subsp. nucleatum ATCC 25586T. | Kim HS, Song SK, Yoo SY, Jin DC, Shin HS, Lim CK, Kim MS, Kim JS, Choe SJ, Kook JK | J Microbiol | 2257 | 2005 | |
| Pathogenicity | Enhanced pathogenicity of Fusobacterium nucleatum adapted to oxidative stress. | Silva VL, Diniz CG, Cara DC, Santos SG, Nicoli JR, Carvalho MA, Farias LM | Microb Pathog | 10.1016/j.micpath.2005.07.002 | 2005 | |
| Metabolism | Identification and characterization of a novel adhesin unique to oral fusobacteria. | Han YW, Ikegami A, Rajanna C, Kawsar HI, Zhou Y, Li M, Sojar HT, Genco RJ, Kuramitsu HK, Deng CX | J Bacteriol | 10.1128/JB.187.15.5330-5340.2005 | 2005 | |
| Metabolism | Protein secretion systems in Fusobacterium nucleatum: genomic identification of Type 4 piliation and complete Type V pathways brings new insight into mechanisms of pathogenesis. | Desvaux M, Khan A, Beatson SA, Scott-Tucker A, Henderson IR | Biochim Biophys Acta | 10.1016/j.bbamem.2005.05.002 | 2005 | |
| Metabolism | Genome analysis of F. nucleatum sub spp vincentii and its comparison with the genome of F. nucleatum ATCC 25586. | Kapatral V, Ivanova N, Anderson I, Reznik G, Bhattacharyya A, Gardner WL, Mikhailova N, Lapidus A, Larsen N, D'Souza M, Walunas T, Haselkorn R, Overbeek R, Kyrpides N | Genome Res | 10.1101/gr.566003 | 2003 | |
| Pathogenicity | Serum antibodies of periodontitis patients compared to the lipopolysaccharides of Porphyromonas gingivalis and Fusobacterium nucleatum. | Onoue S, Imai T, Kumada H, Umemoto T, Kaca W, Isshiki Y, Kaneko A, Kawahara K | Microbiol Immunol | 10.1111/j.1348-0421.2003.tb02785.x | 2003 | |
| Pathogenicity | In vitro effect of laser irradiation on cementum-bound endotoxin isolated from periodontally diseased roots. | Liu CM, Shyu YC, Pei SC, Lan WH, Hou LT | J Periodontol | 10.1902/jop.2002.73.11.1260 | 2002 | |
| Pathogenicity | Activity of endodontic antibacterial agents against selected anaerobic bacteria. | Ferreira CM, da Silva Rosa OP, Torres SA, Ferreira FB, Bernardinelli N | Braz Dent J | 10.1590/s0103-64402002000200008 | 2002 | |
| Pathogenicity | Effect of Fusobacterium nucleatum on the T and B cell responses to Porphyromonas gingivalis in a mouse model. | Gemmell E, Bird PS, Carter CL, Drysdale KE, Seymour GJ | Clin Exp Immunol | 10.1046/j.1365-2249.2002.01852.x | 2002 | |
| Pathogenicity | In vitro effect of intracanal medicaments on strict anaerobes by means of the broth dilution method. | Rosa OP, Torres SA, Ferreira CM, Ferreira FB | Pesqui Odontol Bras | 10.1590/s1517-74912002000100006 | 2002 | |
| Metabolism | Genome sequence and analysis of the oral bacterium Fusobacterium nucleatum strain ATCC 25586. | Kapatral V, Anderson I, Ivanova N, Reznik G, Los T, Lykidis A, Bhattacharyya A, Bartman A, Gardner W, Grechkin G, Zhu L, Vasieva O, Chu L, Kogan Y, Chaga O, Goltsman E, Bernal A, Larsen N, D'Souza M, Walunas T, Pusch G, Haselkorn R, Fonstein M, Kyrpides N, Overbeek R | J Bacteriol | 10.1128/JB.184.7.2005-2018.2002 | 2002 | |
| Pathogenicity | Kinetics of coaggregation of Porphyromonas gingivalis with Fusobacterium nucleatum using an automated microtiter plate assay. | Metzger Z, Featherstone LG, Ambrose WW, Trope M, Arnold RR | Oral Microbiol Immunol | 10.1034/j.1399-302x.2001.016003163.x | 2001 | |
| Pathogenicity | Abscess forming ability of streptococcus milleri group: synergistic effect with Fusobacterium nucleatum. | Nagashima H, Takao A, Maeda N | Microbiol Immunol | 10.1111/j.1348-0421.1999.tb02395.x | 1999 | |
| Pathogenicity | [A comparative in-vitro study of the bactericidal efficacy of sodium hypochlorite and chlorhexidine gluconate plus cetrimide on root canal anaerobic bacterial flora]. | D'Arcangelo C, Varvara G | Minerva Stomatol | 1998 | | |
| Enzymology | Arbitrarily primed polymerase chain reaction fingerprinting and clonal analysis of oral Fusobacterium nucleatum isolates. | George KS, Reynolds MA, Falkler WA Jr | Oral Microbiol Immunol | 10.1111/j.1399-302x.1997.tb00382.x | 1997 | |
| Induction of systemic murine B-cell responses by Fusobacterium nucleatum and Porphyromonas gingivalis. | Nunes IP, Jonsson R, Jensen HB, Bakken V | Oral Microbiol Immunol | 10.1111/j.1399-302x.1996.tb00349.x | 1996 | | |
| Pathogenicity | Extraction and characterization of the smooth-type lipopolysaccharide from Fusobacterium nucleatum JCM 8532 and its biological activities. | Onoue S, Niwa M, Isshiki Y, Kawahara K | Microbiol Immunol | 10.1111/j.1348-0421.1996.tb01075.x | 1996 | |
| Enzymology | The Fusobacterium nucleatum major outer-membrane protein (FomA) forms trimeric, water-filled channels in lipid bilayer membranes. | Kleivdal H, Benz R, Jensen HB | Eur J Biochem | 10.1111/j.1432-1033.1995.310_1.x | 1995 | |
| Pathogenicity | Effect of periodontal treatments on serum IgG antibody titers against periodontopathic bacteria. | Horibe M, Watanabe H, Ishikawa I | J Clin Periodontol | 10.1111/j.1600-051x.1995.tb00798.x | 1995 | |
| Enzymology | Sizing the Fusobacterium nucleatum genome by pulsed-field gel electrophoresis. | Bolstad AI | FEMS Microbiol Lett | 10.1111/j.1574-6968.1994.tb07214.x | 1994 | |
| Genetics | Sequence variability of the 40-kDa outer membrane proteins of Fusobacterium nucleatum strains and a model for the topology of the proteins. | Bolstad AI, Tommassen J, Jensen HB | Mol Gen Genet | 10.1007/BF00280193 | 1994 | |
| Metabolism | Methylation of adenine and cytosine in some strains of Fusobacterium nucleatum. | Bolstad AI, Jensen HB | Microb Pathog | 10.1006/mpat.1993.1012 | 1993 | |
| Cultivation | Growth conditions and outer membrane proteins of Fusobacterium nucleatum. | Bakken V, Hogh BT, Jensen HB | Scand J Dent Res | 10.1111/j.1600-0722.1990.tb00964.x | 1990 | |
| Metabolism | Diisopropylfluorophosphate-binding proteins in the outer membrane of Fusobacterium nucleatum: strain variations. | Brokstad KA, Bakken V, Vasstrand EN, Jensen HB | FEMS Microbiol Lett | 10.1016/0378-1097(90)90289-3 | 1990 | |
| Enzymology | Purification and partial characterization of a major outer-membrane protein of Fusobacterium nucleatum. | Bakken V, Aaro S, Jensen HB | J Gen Microbiol | 10.1099/00221287-135-12-3253 | 1989 | |
| Enzymology | Structural analysis of lipopolysaccharides from Eikenella corrodens by use of murine monoclonal antibodies. | Kato T, Takazoe I, Okuda K | Infect Immun | 10.1128/iai.57.2.656-659.1989 | 1989 | |
| Phylogeny | Production of monoclonal antibodies that recognize specific and cross-reactive antigens of Fusobacterium nucleatum. | Bird PS, Seymour GJ | Infect Immun | 10.1128/iai.55.3.771-777.1987 | 1987 | |
| Phylogeny | Immunoglobulin G response to subgingival gram-negative bacteria in human subjects. | Naito Y, Okuda K, Takazoe I | Infect Immun | 10.1128/iai.45.1.47-51.1984 | 1984 | |
| Metabolism | Pathway of lysine degradation in Fusobacterium nucleatum. | Barker HA, Kahn JM, Hedrick L | J Bacteriol | 10.1128/jb.152.1.201-207.1982 | 1982 | |
| Phylogeny | Reassessing taxonomy and virulence in the Fusobacterium nucleatum group-rebuttal of Fusobacterium animalis clades "Fna C1" and "Fna C2," genome announcement for Fusobacterium watanabei, and description of Fusobacterium paranimalis sp. nov. | Sivertsen A, Forni D, Molteni C, Bivand J, Dimmen G, Bruvold TS, Sironi M, Kommedal O. | mBio | 10.1128/mbio.00941-25 | 2025 | |
| Phylogeny | Fretibacterium fastidiosum gen. nov., sp. nov., isolated from the human oral cavity. | Vartoukian SR, Downes J, Palmer RM, Wade WG | Int J Syst Evol Microbiol | 10.1099/ijs.0.041038-0 | 2012 | |
| Phylogeny | Proposal of three subspecies of Fusobacterium nucleatum Knorr 1922: Fusobacterium nucleatum subsp. nucleatum subsp. nov., comb. nov.; Fusobacterium nucleatum subsp. polymorphum subsp. nov., nom. rev., comb. nov.; and Fusobacterium nucleatum subsp. vincentii subsp. nov., nom. rev., comb. nov. | Dzink JL, Sheenan MT, Socransky SS | Int J Syst Bacteriol | 10.1099/00207713-40-1-74 | 1990 | |
How to citeIf you want to cite this particular strain cite the following doi:
https://doi.org/10.13145/bacdive5765.20251217.10
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BacDive in 2025: the core database for prokaryotic strain data
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