Strain identifier
BacDive ID: 11700
Type strain: 
Species: Haemophilus influenzae
Strain Designation: 641
Strain history: <- ATCC; ATCC 9795 <- Walter Reed Army Medical Center, Washington, D.C., USA; AMC 36-A-4 <- M. Pittman; 641
NCBI tax ID(s): 727 (species)
version 8.1 (current version)
General
@ref: 3773
BacDive-ID: 11700
DSM-Number: 10001
keywords: genome sequence, 16S sequence, Bacteria, microaerophile, mesophilic, Gram-negative
description: Haemophilus influenzae 641 is a microaerophile, mesophilic, Gram-negative bacterium that was isolated from spinal fluid of patient with meningitis.
NCBI tax id
- NCBI tax id: 727
- Matching level: species
strain history
- @ref: 3773
- history: <- ATCC; ATCC 9795 <- Walter Reed Army Medical Center, Washington, D.C., USA; AMC 36-A-4 <- M. Pittman; 641
doi: 10.13145/bacdive11700.20230509.8.1
Name and taxonomic classification
LPSN
- @ref: 20215
- description: domain/bacteria
- keyword: phylum/pseudomonadota
- domain: Bacteria
- phylum: Pseudomonadota
- class: Gammaproteobacteria
- order: Pasteurellales
- family: Pasteurellaceae
- genus: Haemophilus
- species: Haemophilus influenzae
- full scientific name: Haemophilus influenzae corrig. (Lehmann and Neumann 1896) Winslow et al. 1917 (Approved Lists 1980)
synonyms
@ref synonym 20215 Hemophilus influenzae 20215 Bacterium influenzae
@ref: 3773
domain: Bacteria
phylum: Proteobacteria
class: Gammaproteobacteria
order: Pasteurellales
family: Pasteurellaceae
genus: Haemophilus
species: Haemophilus influenzae
full scientific name: Haemophilus influenzae (Lehmann and Neumann 1896) Winslow et al. 1917
strain designation: 641
type strain: no
Morphology
cell morphology
- @ref: 69480
- gram stain: negative
- confidence: 99.988
colony morphology
- @ref: 3773
- incubation period: 1-2 days
Culture and growth conditions
culture medium
| @ref | name | growth | link | composition |
|---|---|---|---|---|
| 3773 | HAEMOPHILUS MEDIUM (DSMZ Medium 804) | yes | https://mediadive.dsmz.de/medium/804 | Name: HAEMOPHILUS MEDIUM (DSMZ Medium 804) Composition: Mueller-Hinton broth 21.0 g/l Yeast extract 5.0 g/l Distilled water |
| 3773 | COLUMBIA BLOOD AGAR (DSMZ Medium 429) | yes | https://mediadive.dsmz.de/medium/429 | Name: COLUMBIA BLOOD AGAR (DSMZ Medium 429) Composition: Horse blood 40.0 g/l Columbia agar base |
culture temp
- @ref: 3773
- growth: positive
- type: growth
- temperature: 37
- range: mesophilic
Physiology and metabolism
oxygen tolerance
- @ref: 3773
- oxygen tolerance: microaerophile
spore formation
| @ref | spore formation | confidence |
|---|---|---|
| 69481 | no | 100 |
| 69480 | no | 99.994 |
metabolite utilization
- @ref: 68377
- Chebi-ID: 17306
- metabolite: maltose
- utilization activity: -
- kind of utilization tested: builds acid from
enzymes
| @ref | value | activity | ec |
|---|---|---|---|
| 68377 | proline-arylamidase | - | 3.4.11.5 |
| 68377 | beta-galactosidase | - | 3.2.1.23 |
API NH
| @ref | PEN | GLU | FRU | MAL | SAC | ODC | URE | LIP | PAL | beta GAL | ProA | GGT | IND |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 3773 | + | + | - | - | - | + | - | + | - | - | - | + | - |
| 3773 | + | - | - | - | + | + | - | + | - | - | - | + | - |
| 3773 | - | + | + | - | - | + | + | - | + | - | - | + | + |
| 3773 | - | + | + | - | - | - | + | - | + | - | - | - | + |
| 3773 | - | + | - | - | - | + | + | - | + | - | - | - | + |
Isolation, sampling and environmental information
isolation
| @ref | sample type | country | origin.country | continent | sampling date |
|---|---|---|---|---|---|
| 3773 | spinal fluid of patient with meningitis | USA | USA | North America | |
| 44970 | Human cerebrospinal fluid,meningitidis | 1944 |
isolation source categories
| Cat1 | Cat2 | Cat3 |
|---|---|---|
| #Infection | #Disease | #Meningitis |
| #Infection | #Patient | |
| #Host Body Product | #Fluids | #Cerebrospinal fluid |
taxonmaps
- @ref: 69479
- File name: preview.99_36.png
- url: https://microbeatlas.org/index.html?action=taxon&taxon_id=90_18;96_30;97_31;98_34;99_36&stattab=map
- Last taxonomy: Haemophilus influenzae
- 16S sequence: AY613700
- Sequence Identity:
- Total samples: 31536
- soil counts: 173
- aquatic counts: 597
- animal counts: 30711
- plant counts: 55
Safety information
risk assessment
- @ref: 3773
- biosafety level: 2
- biosafety level comment: Risk group (German classification)
Sequence information
16S sequences
- @ref: 20218
- description: Haemophilus influenzae strain ATCC9795 16S ribosomal RNA gene, partial sequence
- accession: AY613700
- length: 1538
- database: ena
- NCBI tax ID: 727
Genome sequences
| @ref | description | accession | assembly level | database | NCBI tax ID |
|---|---|---|---|---|---|
| 66792 | Haemophilus influenzae strain FDAARGOS_1479 | 727.3022 | complete | patric | 727 |
| 66792 | Haemophilus influenzae strain FDAARGOS_1479 | 727.3034 | complete | patric | 727 |
| 66792 | Haemophilus influenzae strain FDAARGOS_1479 | 727.3043 | complete | patric | 727 |
| 66792 | Haemophilus influenzae strain FDAARGOS_1479 | 727.3030 | complete | patric | 727 |
Genome-based predictions
predictions
| trait | prediction | confidence | training_data |
|---|---|---|---|
| spore-forming | no | 100 | no |
| motile | no | 91.299 | no |
| flagellated | no | 95.486 | no |
| gram-positive | no | 98.029 | no |
| anaerobic | no | 94.303 | no |
| aerobic | no | 95.648 | no |
| halophile | yes | 56.552 | no |
| spore-forming | no | 98.527 | no |
| thermophile | no | 98.139 | yes |
| glucose-util | no | 51.729 | no |
| glucose-ferment | yes | 53.316 | no |
External links
@ref: 3773
culture collection no.: CCUG 7317 A, DSM 10001, ATCC 9795, NCTC 8467, AMC 36-A-4
straininfo link
- @ref: 80920
- straininfo: 35127
literature
| topic | Pubmed-ID | title | authors | journal | DOI | year | mesh | topic2 |
|---|---|---|---|---|---|---|---|---|
| Enzymology | 1375253 | Recombinant porin of Haemophilus influenzae type b. | Coulton JW, Chin AC, Vachon V | J Infect Dis | 10.1093/infdis/165-supplement_1-s188 | 1992 | Bacterial Outer Membrane Proteins/biosynthesis/*genetics/isolation & purification, Baculoviridae/genetics, Chromatography, Affinity, Cloning, Molecular, Electrophoresis, Polyacrylamide Gel, *Gene Expression Regulation, Bacterial, Genetic Vectors, Haemophilus influenzae/*chemistry/genetics/metabolism, Immunoblotting, Ion Channels/*genetics, Porins, Recombinant Proteins/biosynthesis/genetics/isolation & purification | Phylogeny |
| Pathogenicity | 3897971 | [Comparison of the growth curves of Escherichia coli and Haemophilus influenzae subjected to ampicillin and amoxicillin]. | Yourassowsky E, van der Linden MP, Lismont MJ, Crokaert F, Glupczynski Y | Pathol Biol (Paris) | 1985 | Amoxicillin/*pharmacology, Ampicillin/*pharmacology, Dose-Response Relationship, Drug, Escherichia coli/drug effects/*growth & development, Haemophilus influenzae/drug effects/*growth & development, Microbial Sensitivity Tests |
Reference
| @id | authors | catalogue | doi/url | title | journal | pubmed |
|---|---|---|---|---|---|---|
| 3773 | Curators of the DSMZ | Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSM 10001) | https://www.dsmz.de/collection/catalogue/details/culture/DSM-10001 | |||
| 20215 | Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M. | 10.1099/ijsem.0.004332 | List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ | |||
| 20218 | Verslyppe, B., De Smet, W., De Baets, B., De Vos, P., Dawyndt P. | 10.1016/j.syapm.2013.11.002 | StrainInfo introduces electronic passports for microorganisms. | Syst Appl Microbiol. 37: 42-50 2014 | 24321274 | |
| 44970 | Curators of the CCUG | Culture Collection University of Gothenburg (CCUG) (CCUG 7317 A) | https://www.ccug.se/strain?id=7317 | |||
| 66792 | Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann | https://diaspora-project.de/progress.html#genomes | Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) | |||
| 68377 | Automatically annotated from API NH | |||||
| 69479 | João F Matias Rodrigues, Janko Tackmann,Gregor Rot, Thomas SB Schmidt, Lukas Malfertheiner, Mihai Danaila,Marija Dmitrijeva, Daniela Gaio, Nicolas Näpflin and Christian von Mering. University of Zurich. | https://microbeatlas.org/ | MicrobeAtlas 1.0 beta | |||
| 69480 | Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann | https://diaspora-project.de/progress.html#genomes | Predictions based on genome sequence made in the Diaspora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) | |||
| 69481 | Xiao-Yin To, René Mreches, Martin Binder, Alice C. McHardy, Philipp C. Münch | 10.21203/rs.3.rs-2527258/v1 | Predictions based on the model GenomeNet Sporulation v. 1 | |||
| 80920 | Reimer, L.C., Lissin, A.,Schober, I., Witte,J.F., Podstawka, A., Lüken, H., Bunk, B.,Overmann, J. | 10.60712/SI-ID35127.1 | StrainInfo: A central database for resolving microbial strain identifiers |