Streptococcus mutans (DSM 6178, ATCC 35668, CCUG 35176)

Name: Streptococcus mutans (DSM 6178, ATCC 35668, CCUG 35176)
Creator: BacDive
License: http://creativecommons.org/licenses/by/4.0/

BacDive ID 14735

Type strain

Strain Designation LRA 28 02 81, LRA 028 02 81

Culture col. no. DSM 6178 ATCC 35668 CCUG 35176 LRA 28 02 81 CIP 103694 1 more

NCBI tax ID(s) 1309

Special Collections DSMZ CCUG CIP

History DSMZ <- ATCC; ATCC 35668 <- D. Androphy; LRA 28 02 81 CIP <- 1993, R. Mercier, bioMérieux, La Balme-les-Grottes, France: strain LRA 028 02 81 <- C. Colman, Central Pub. Hlth. Lab., London, UK

Links

Streptococcus mutans LRA 28 02 81 is a microaerophile, Gram-positive, coccus-shaped bacterium of the family Streptococcaceae.

Gram-positive coccus-shaped microaerophile genome sequence Bacteria

Name and taxonomic classification

SI-ID 41217

ATCC 35668,CCUG 35176,CIP 103694,DSM 6178,NCIMB 13700,CGMCC 1.2500

@ref 20215

Last LPSN update 2026-05-29 08:28:21

Domain Bacteria

Phylum Bacillota

Class Bacilli

Order Lactobacillales

Family Streptococcaceae

Genus Streptococcus

Species Streptococcus mutans

Full scientific name Streptococcus mutans Clarke 1924 (Approved Lists 1980)

BacDive ID	Other strains from **Streptococcus mutans** (47)	Type strain
14736	S. mutans EML 1738, DSM 20523, ATCC 25175, IFO 13955, ... (type strain)
136800	S. mutans 491012, CIP 103735
138139	S. mutans 10595, CIP 104995
142873	S. mutans CCUG 15479
144493	S. mutans CCUG 25299
144615	S. mutans CCUG 25949
144684	S. mutans CCUG 26208
145083	S. mutans CCUG 27624, CNCTC 11/77
145084	S. mutans CCUG 27625, CNCTC 1/80, LMG 14559
145249	S. mutans CCUG 27952
145305	S. mutans CCUG 28133
145519	S. mutans CCUG 28737
146360	S. mutans CCUG 31023
146370	S. mutans CCUG 31045
146530	S. mutans CCUG 31378, CCM 7554
146536	S. mutans CCUG 31386
146658	S. mutans CCUG 31738
146753	S. mutans CCUG 32068
146771	S. mutans CCUG 32092
146814	S. mutans CCUG 32169
147155	S. mutans CCUG 32960
147498	S. mutans CCUG 33704, CCM 7555
147595	S. mutans CCUG 33855
148198	S. mutans CCUG 35023
148892	S. mutans CCUG 36554
150041	S. mutans CCUG 38906
150135	S. mutans CCUG 39070
150660	S. mutans CCUG 41890
151213	S. mutans CCUG 43479
151235	S. mutans CCUG 43520 B
151864	S. mutans CCUG 45091
152112	S. mutans CCUG 45825
152578	S. mutans CCUG 47111
152963	S. mutans CCUG 48140
153104	S. mutans CCUG 48499
153646	S. mutans CCUG 50477
154269	S. mutans CCUG 52940
154666	S. mutans CCUG 54774
155085	S. mutans CCUG 56427
155945	S. mutans CCUG 59718
155946	S. mutans CCUG 59719
156050	S. mutans CCUG 60222
156301	S. mutans CCUG 61102
156870	S. mutans CCUG 66205
157034	S. mutans CCUG 68963
157082	S. mutans CCUG 69401
165121	S. mutans JCM 5175

Morphology

Cell morphology

@ref	Gram stain	Cell shape	Motility	Confidence
125438				90.5
121206	positive	coccus-shaped

Colony morphology

@ref	Type of hemolysis	Hemolysis ability	Incubation period
2510	gamma	0	1-2 days
121206		0

Culture and growth conditions

Culture medium

@ref	Name	Medium link	Composition
2510	COLUMBIA BLOOD MEDIUM (DSMZ Medium 693)	Medium recipe at MediaDive	Name: COLUMBIA BLOOD MEDIUM (DSMZ Medium 693) Composition: Defibrinated sheep blood 50.0 g/l Columbia agar base
2510	TRYPTICASE SOY YEAST EXTRACT MEDIUM (DSMZ Medium 92)	Medium recipe at MediaDive	Name: TRYPTICASE SOY YEAST EXTRACT MEDIUM (DSMZ Medium 92) Composition: Trypticase soy broth 30.0 g/l Agar 15.0 g/l Yeast extract 3.0 g/l Distilled water
35120	MEDIUM 6 - Columbia agar with 10 % horse blood		Distilled water make up to (1000.000 ml);Columbia agar (39.000 g);Horseblood (100.000 ml)
121206	CIP Medium 6	Medium recipe at CIP
121206	CIP Medium 72	Medium recipe at CIP

Culture temp

@ref	Growth	Type	Temperature (°C)
2510	positive	growth	37
35120	positive	growth	37
121206	positive	growth	25-37
121206	negative	growth	10
121206	negative	growth	45

Physiology and metabolism

Oxygen tolerance

@ref	Oxygen tolerance	Confidence
2510	microaerophile
121206	facultative anaerobe
125439	obligate aerobe	96.023

Spore formation

@ref	Spore formation	Confidence
125439		98.783
125438		90.882

Halophily

@ref	Salt	Growth	Tested relation	Concentration
121206	NaCl		growth	6.5 %

Metabolite utilization

@ref	Chebi-ID	Metabolite	Utilization activity	Kind of utilization tested
68381	40585 ChEBI	alpha-cyclodextrin	-	builds acid from	from API rID32STR
68381	29016 ChEBI	arginine	-	hydrolysis	from API rID32STR
68370	29016 ChEBI	arginine	-	hydrolysis	from API 20STR
68381	18333 ChEBI	D-arabitol	-	builds acid from	from API rID32STR
68381	16899 ChEBI	D-mannitol	+	builds acid from	from API rID32STR
68370	16899 ChEBI	D-mannitol	+	builds acid from	from API 20STR
68370	16988 ChEBI	D-ribose	-	builds acid from	from API 20STR
68370	17924 ChEBI	D-sorbitol	+	builds acid from	from API 20STR
121206	4853 ChEBI	esculin	+	hydrolysis
68370	4853 ChEBI	esculin	+	hydrolysis	from API 20STR
68381	28087 ChEBI	glycogen	-	builds acid from	from API rID32STR
68370	28087 ChEBI	glycogen	-	builds acid from	from API 20STR
68381	606565 ChEBI	hippurate	-	hydrolysis	from API rID32STR
121206	606565 ChEBI	hippurate	-	hydrolysis
68370	606565 ChEBI	hippurate	-	hydrolysis	from API 20STR
68370	15443 ChEBI	inulin	+	builds acid from	from API 20STR
68381	30849 ChEBI	L-arabinose	-	builds acid from	from API rID32STR
68370	30849 ChEBI	L-arabinose	-	builds acid from	from API 20STR
68381	17716 ChEBI	lactose	+	builds acid from	from API rID32STR
68370	17716 ChEBI	lactose	+	builds acid from	from API 20STR
68381	17306 ChEBI	maltose	+	builds acid from	from API rID32STR
68381	6731 ChEBI	melezitose	-	builds acid from	from API rID32STR
68381	28053 ChEBI	melibiose	+	builds acid from	from API rID32STR
121206	17632 ChEBI	nitrate	-	reduction
121206	16301 ChEBI	nitrite	-	reduction
68381	27941 ChEBI	pullulan	-	builds acid from	from API rID32STR
68381	16634 ChEBI	raffinose	+	builds acid from	from API rID32STR
68370	16634 ChEBI	raffinose	+	builds acid from	from API 20STR
68381	30911 ChEBI	sorbitol	+	builds acid from	from API rID32STR
68370	28017 ChEBI	starch	-	builds acid from	from API 20STR
68381	17992 ChEBI	sucrose	+	builds acid from	from API rID32STR
68381	27082 ChEBI	trehalose	+	builds acid from	from API rID32STR
68370	27082 ChEBI	trehalose	+	builds acid from	from API 20STR
68381	16199 ChEBI	urea	-	hydrolysis	from API rID32STR

Antibiotic resistance

@ref	Metabolite	Is sensitive	Is resistant
121206	0129 (2,4-Diamino-6,7-di-iso-propylpteridine phosphate)

Metabolite production

@ref	Chebi-ID	Metabolite	Production
68381	15688 ChEBI	acetoin		from API rID32STR
68370	15688 ChEBI	acetoin		from API 20STR

Metabolite tests

@ref	Chebi-ID	Metabolite	Voges-proskauer-test
68381	15688 ChEBI	acetoin	+	from API rID32STR
68370	15688 ChEBI	acetoin	+	from API 20STR
121206	15688 ChEBI	acetoin	+

Enzymes

@ref	Value	Activity	Ec
68382	acid phosphatase	-	3.1.3.2	from API zym
121206	alcohol dehydrogenase	-	1.1.1.1
68382	alkaline phosphatase	-	3.1.3.1	from API zym
68370	alkaline phosphatase	-	3.1.3.1	from API 20STR
68381	alkaline phosphatase	-	3.1.3.1	from API rID32STR
68382	alpha-chymotrypsin	-	3.4.21.1	from API zym
68382	alpha-fucosidase	-	3.2.1.51	from API zym
68381	alpha-galactosidase	+	3.2.1.22	from API rID32STR
68382	alpha-galactosidase	-	3.2.1.22	from API zym
68370	alpha-galactosidase	+	3.2.1.22	from API 20STR
68382	alpha-glucosidase	+	3.2.1.20	from API zym
68382	alpha-mannosidase	-	3.2.1.24	from API zym
68381	arginine dihydrolase	-	3.5.3.6	from API rID32STR
68370	arginine dihydrolase	-	3.5.3.6	from API 20STR
68381	beta-galactosidase	-	3.2.1.23	from API rID32STR
68382	beta-galactosidase	-	3.2.1.23	from API zym
121206	beta-galactosidase	-	3.2.1.23
68370	beta-galactosidase	-	3.2.1.23	from API 20STR
68381	beta-glucosidase	+	3.2.1.21	from API rID32STR
68382	beta-glucosidase	+	3.2.1.21	from API zym
68370	beta-glucosidase	+	3.2.1.21	from API 20STR
68381	beta-glucuronidase	-	3.2.1.31	from API rID32STR
68382	beta-glucuronidase	-	3.2.1.31	from API zym
68370	beta-glucuronidase	-	3.2.1.31	from API 20STR
68381	beta-mannosidase	-	3.2.1.25	from API rID32STR
2510	catalase	+	1.11.1.6
121206	catalase	-	1.11.1.6
68382	cystine arylamidase	-	3.4.11.3	from API zym
2510	cytochrome-c oxidase	-	1.9.3.1
68382	esterase (C 4)	+		from API zym
68382	esterase lipase (C 8)	+		from API zym
121206	gamma-glutamyltransferase	-	2.3.2.2
68382	leucine arylamidase	+	3.4.11.1	from API zym
68370	leucine arylamidase	+	3.4.11.1	from API 20STR
68382	lipase (C 14)	-		from API zym
121206	lysine decarboxylase	-	4.1.1.18
68382	N-acetyl-beta-glucosaminidase	-	3.2.1.52	from API zym
68381	N-acetyl-beta-glucosaminidase	-	3.2.1.52	from API rID32STR
68382	naphthol-AS-BI-phosphohydrolase	+		from API zym
121206	ornithine decarboxylase	-	4.1.1.17
121206	oxidase	-
68370	pyrrolidonyl arylamidase	-	3.4.19.3	from API 20STR
68382	trypsin	-	3.4.21.4	from API zym
68381	urease	-	3.5.1.5	from API rID32STR
68382	valine arylamidase	-		from API zym

API zym

@ref	Control	Alkaline phosphatase	Esterase (C 4)	2-naphtyl caprylateEsterase Lipase (C 8)	Lipase (C 14)	L-leucyl-2-naphthylamideLeucine arylamidase	L-valyl-2-naphthylamideValine arylamidase	L-cystyl-2-naphthylamideCystine arylamidase	Trypsin	alpha- Chymotrypsin	Acid phosphatase	Naphthol-AS-BI-phosphateNaphthol-AS-BI-phosphohydrolase	alpha- Galactosidase	beta- Galactosidase	beta- Glucuronidase	alpha- Glucosidase	beta- Glucosidase	N-acetyl-beta- glucosaminidase	alpha- Mannosidase	alpha- Fucosidase
121206	-	-	+	+	-	+	-	-	-	-	-	+	-	-	-	+	+	-	-	-

API 20STR

@ref	Acetoin production (Voges Proskauer test)VP	HIP	ESC	PYRA	alpha GAL	beta GUR	beta GAL	PAL	LAP	ADH	RIB	ARA	MAN	SOR	LAC	TRE	INU	RAF	AMD	GLYG	beta hemolysis presentbeta HEM
2510	+	-	+	-	+	-	-	-	+	-	-	-	+	+	+	+	+	+	-	-	-
52570	+	-	+	-	+	-	-	-	+	-	-	-	+	+	+	+	+	+	-	-	-

API rID32STR

@ref	ADH (Arg)	beta GLU	beta GAR	beta GUR	alpha GAL	PAL	RIB	MAN	SOR	LAC	TRE	RAF	SAC	LARA	DARL	Acid from alpha-cyclodextrinCDEX	Acetoin production (Voges Proskauer test)VP	Alanyl-Phenylalanyl-Proline arylamidaseAPPA	beta GAL	Pyrrolidonyl arylamidasePyrA	N-Acetyl-glucosaminidasebeta NAG	Glycyl-tryptophan arylamidaseGTA	HIP	GLYG	PUL	MAL	MEL	MLZ	Acidification of methyl beta-D-glucopyranosideMbeta DG	TAG	beta MAN	URE
52570	-	+	-	-	+	-	-	+	+	+	+	+	+	-	-	-	+	+	-	-	-	-	-	-	-	+	+	-	+	-	-	-
2510	-	+	-	-	+	-	-	+	+	+	+	+	+	-	-	-	+	+	-	-	-	-	-	-	-	+	+	-	-	-	-	-
2510	-	+	-	-	+	-	+	+	+	+	+	+	+	-	-	-	+	+	-	-	-	-	-	-	-	+	+	-	+	+	-	-
2510	-	+	-	-	+	-	-	+	+	+	+	+	+	-	-	-	+	+/-	-	+/-	-	+/-	-	-	-	+	+	-	-	-	-	-
2510	-	+	-	-	+	-	-	+	+	+	+	+	+	-	-	-	+	+	-	-	-	-	-	-	-	+	+	-	+/-	-	-	-
2510	-	+	-	-	+	-	-	+	+	+	+	+	+	-	-	-	+	+	-	-	-	-	-	-	-	+	+	-	+	-	-	-

Isolation, sampling and environmental information

Interaction and safety

Risk assessment

@ref	Biosafety level	Biosafety level comment
2510	2	Risk group (German classification) According to TRBA 466
121206	2	Risk group (French classification) According to TRBA 466

Sequence information

Genome sequences

@ref	Description	Assembly level	INSDC accession	BV-BRC accession	NCBI tax ID	Score
124043	ASM1934486v1 assembly for Streptococcus mutans FDAARGOS_1457	contig	GCA_019344865	1309.468	1309	37.2

Genome-based predictions

Predictions

Predictions from Deep Learning for Genome Sequence Data. R package version 0.3.1 based on: ASM1934486v1 assembly for Streptococcus mutans FDAARGOS_1457
NCBI: GCA_019344865

@ref	Trait	Model	Prediction	Confidence in %	In training data
125439	oxygen_tolerance	BacteriaNetⓘ	obligate aerobe	96.02	no
125439	gram_stain	BacteriaNetⓘ	negative	71.09	no
125439	motility	BacteriaNetⓘ	no	77.01	no
125439	spore_formation	BacteriaNetⓘ	no	98.78	no

Predictions from bacterial phenotypic traits through improved machine learning using high-quality, curated datasets based on: Streptococcus mutans strain FDAARGOS_1457 strain Not applicable
PATRIC: 1309.468

@ref	Trait	Model	Prediction	Confidence in %	In training data
125438	gram-positive	gram-positiveⓘ	yes	87.09	no
125438	anaerobic	anaerobicⓘ	no	85.14	no
125438	spore-forming	spore-formingⓘ	no	90.88	no
125438	aerobic	aerobicⓘ	no	96.26	yes
125438	thermophilic	thermophileⓘ	no	96.44	yes
125438	flagellated	motile2+ⓘ	no	90.50	no

Literature

Topic	Title	Authors	Journal	DOI	Year
Genetics	Chlorhexidine digluconate mouthwash alters the oral microbial composition and affects the prevalence of antimicrobial resistance genes.	Bartsch S, Kohnert E, Kreutz C, Woelber JP, Anderson A, Burkhardt AS, Hellwig E, Buchalla W, Hiller KA, Ratka-Krueger P, Cieplik F, Al-Ahmad A.	Front Microbiol	10.3389/fmicb.2024.1429692	2024
	In Vitro Selection of Lactobacillus and Bifidobacterium Probiotic Strains for the Management of Oral Pathobiont Infections Associated to Systemic Diseases.	Zanetta P, Squarzanti DF, di Coste A, Rolla R, Valletti PA, Garzaro M, Dell'Era V, Amoruso A, Pane M, Azzimonti B.	Int J Mol Sci	10.3390/ijms232416163	2022
	The oral microbiota is a reservoir for antimicrobial resistance: resistome and phenotypic resistance characteristics of oral biofilm in health, caries, and periodontitis.	Anderson AC, von Ohle C, Frese C, Boutin S, Bridson C, Schoilew K, Peikert SA, Hellwig E, Pelz K, Wittmer A, Wolff D, Al-Ahmad A.	Ann Clin Microbiol Antimicrob	10.1186/s12941-023-00585-z	2023
Pathogenicity	Antibacterial activity of two phloroglucinols, flavaspidic acids AB and PB, from Dryopteris crassirhizoma.	Lee HB, Kim JC, Lee SM.	Arch Pharm Res	10.1007/s12272-009-1502-9	2009
	Evaluation of the effect of different infant formulas on Streptococcus mutans biofilm formation: an in-vitro study.	Baninajarian H, Tahmourespour A, Vedaei A, Ghasemi D.	Saudi Dent J	10.1007/s44445-025-00014-1	2025
	Addition of silver nanoparticles to universal adhesive: In vitro effect on biofilm and shear bond strength.	Favaro JC, Geha O, Canavarros TN, Nascimento A, Lopes MB, Guiraldo RD, Berger SB.	Braz Dent J	10.1590/0103-644020256255	2025
	Formulation and antimicrobial activity of a probiotic mouth freshener with phycoerythrin, Artemisia aucheri and encapsulated Lactobacillus bifidus targeting Streptococcus mutans.	Salimi Manjili D, Nowruzi B, Ghane M.	J Oral Biol Craniofac Res	10.1016/j.jobcr.2025.09.006	2025
	Formulation and Evaluation of a Licorice-Resveratrol Lollipop for Targeting Streptococcus mutans Biofilm and Antimicrobial Resistance	Patil S, Powar G, Harale S, Galatage S, Liu S, Lopes B, Sharma D, Patil A, Wen F.	Infect Drug Resist		2025
	Effect of nano liposomal herbal extracts against biofilm formation and adherence of streptococcus mutans.	Baseri M, Naseri A, Radmand F, Hamishehkar H, Memar MY, Ebrahimi A, Asnaashari S, Kouhsoltani M.	Sci Rep	10.1038/s41598-025-08856-9	2025
	Effect of the crystalline structure of ceramic orthodontic brackets on the adherence of Streptococcus mutans and Candida albicans: An in vitro study.	Hasanzadeh Azhiri A, Tashakor A, Mirmohammadi K, Rasooli R.	Dent Res J (Isfahan)	10.4103/drj.drj_84_24	2024
	Efficacy of sealants with surface pre-reacted glass (S-PRG) in retention, fissure penetration and occlusal caries Inhibition : Short title: efficacy of S-PRG sealants.	Yeh SHC, Abdalla MMA, Lam PPY, Yiu CKY.	Clin Oral Investig	10.1007/s00784-025-06551-7	2025
	Evaluation of the Antibacterial and Anti-Biofilm Activity of Chitosan-Arginine Nanoparticles and Sodium Fluoride against Streptococcus mutans.	Daneshyar F, Alikhani MY, Tayebi S, Abedi Firouzjaei D.	Int J Mol Cell Med	10.22088/ijmcm.bums.14.2.637	2025
	Antibacterial and antibiofilm activities of tribulus terrestris methanolic extract against Streptococcus mutans, Streptococcus sobrinus, and Lactobacillus acidophilus: An in vitro study.	Azarm A, Ayoobi F, Zare-Bidaki M, Taheri M, Zarandi ER.	Dent Res J (Isfahan)		2024
	Effect of medicated toothpastes and Tooth Mousse on cariogenic microbes of the oral cavity: An in vitro study.	Hegde MN, Hegde NN, Shetty P, Hegde NN, Vittal CL, Ravinanthan M.	J Conserv Dent Endod	10.4103/jcde.jcde_340_24	2024
	Synergistic antimicrobial and probiotic activity of lactic acid bacteria isolated from Tarkhineh against Candida albicans.	Kiani A, Nami Y, Barghi A, Salehian M, Goudarzi F, Haghshenas B.	Sci Rep	10.1038/s41598-025-07549-7	2025
	Antibacterial effect of resveratrol extract compared to chlorhexidine mouthwash against primary cariogenic pathogen, Streptococcus mutans.	Pournasir M, Alavi FN, Davalloo RT, Ebrahim-Saraie HS, Ghaffari ME.	J Clin Exp Dent	10.4317/jced.61456	2024
	Positional Fluorination of Fmoc-Phenylalanine Modulates Hydrogel Structure and Antibacterial Activity.	Doitch O, Rattner N, Cohen-Gerassi D, Dan Y, Rencus-Lazar S, Aviv M, Adler-Abramovich L.	Biomacromolecules	10.1021/acs.biomac.5c00481	2025
Proteome	Comparing proteome changes involved in biofilm formation by Streptococcus mutans after exposure to sucrose and starch.	Rezaei T, Kamounah FS, Khodadadi E, Mehramouz B, Gholizadeh P, Yousefi L, Ganbarov K, Ghotaslou R, Yousefi M, Asgharzadeh M, Eslami H, Taghizadeh S, Pirzadeh T, Kafil HS.	Biotechnol Appl Biochem	10.1002/bab.2442	2023
	Determination of streptococcus mutans retention in acidic and neutral pH artificial saliva environment of all-ceramic materials with different surface treatment.	Hayran Y, Kuscu S, Aydin A.	BMC Oral Health	10.1186/s12903-024-05386-0	2025
	Antimicrobial Efficacy of Teucrium polium L. Extracts for Dental Caries: Green Extraction Techniques and Bioactive Compounds.	Javadpour K, Shekarchizadeh H, Goli M, Moradiyan Tehrani H.	Food Sci Nutr	10.1002/fsn3.4718	2025
	Herbal remedies for oral and dental health: a comprehensive review of their multifaceted mechanisms including antimicrobial, anti-inflammatory, and antioxidant pathways.	Anwar MA, Sayed GA, Hal DM, Hafeez MSAE, Shatat AS, Salman A, Eisa NM, Ramadan A, El-Shiekh RA, Hatem S, Aly SH.	Inflammopharmacology	10.1007/s10787-024-01631-8	2025
	Antibacterial and Anti-Glucosyltransferase Activity of Verbascum speciosum Against Cariogenic Streptococci.	Pourmoslemi S, Larki-Harchegani A, Daneshyar S, Dastan D, Nili-Ahmadabadi A, Jazaeri M.	J Pharmacopuncture	10.3831/kpi.2023.26.2.139	2023
	Biofilm targeting with chitosan-based nanohydrogel containing Quercus infectoria G. Olivier extract against Streptococcus mutans: new formulations of a traditional natural product.	Karimi Y, Rashidipour M, Iranzadasl M, Ahmadi MH, Sarabi MM, Farzaneh F.	BMC Complement Med Ther	10.1186/s12906-024-04696-8	2024
	Lavandula pedunculata subsp. atlantica: A Multifunctional Essential Oil for Potentially Combating Microbial Infections and Inflammatory Processes.	Castagliuolo G, Badalamenti N, Ilardi V, Fontana G, Antonini D, Varcamonti M, Bruno M, Zanfardino A.	Molecules	10.3390/molecules30112267	2025
	Comparative Analysis of Antimicrobial Properties and Physical Properties of Mineral Trioxide Aggregate Mixed With Distilled Water, Chlorhexidine, and Sodium Hypochlorite Solutions: An In Vitro Study.	Suresh B, Ravindran V.	Cureus	10.7759/cureus.67563	2024
	Photoinactivation Effects of Curcumin, Nano-curcumin, and Erythrosine on Planktonic and Biofilm Cultures of Streptococcus mutans.	Ahrari F, Nazifi M, Mazhari F, Ghazvini K, Menbari S, Fekrazad R, Babaei K, Banihashemrad A.	J Lasers Med Sci	10.34172/jlms.2024.07	2024
	Natural compounds: new therapeutic approach for inhibition of Streptococcus mutans and dental caries.	Kashi M, Varseh M, Hariri Y, Chegini Z, Shariati A.	Front Pharmacol	10.3389/fphar.2025.1548117	2025
	Antimicrobial Potential of Brassica oleracea Extracts (White and Broccoli) and Their Resistance Compared to Doxycycline Against Gram-Positive and Gram-Negative Bacteria.	Rahmani M, Esmaeili A, Taherkhani M.	Food Sci Nutr	10.1002/fsn3.4345	2024
	Antimicrobial Activity and Mode of Action of N-Heterocyclic Carbene Silver(I) Complexes.	Castagliuolo G, Di Napoli M, Zangmo T, Szpunar J, Ronga L, Zanfardino A, Varcamonti M, Tesauro D.	Molecules	10.3390/molecules30010076	2024
	In vitro antimicrobial and antibiofilm screening of eighteen Iranian medicinal plants.	Hamidi M, Toosi AM, Javadi B, Asili J, Soheili V, Shakeri A.	BMC Complement Med Ther	10.1186/s12906-024-04437-x	2024
	Polymer-Based Hydroxyapatite-Silver Composite Resin with Enhanced Antibacterial Activity for Dental Applications.	Garibay-Alvarado JA, Garcia-Zamarron DJ, Silva-Holguin PN, Donohue-Cornejo A, Cuevas-Gonzalez JC, Espinosa-Cristobal LF, Ruiz-Baltazar AJ, Reyes-Lopez SY.	Polymers (Basel)	10.3390/polym16142017	2024
	Antibacterial Effect of Ozone on Cariogenic Bacteria and Its Potential Prejudicial Effect on Dentin Bond Strength-An In Vitro Study.	Santos M, Leandro F, Barroso H, Delgado AHS, Proenca L, Polido M, Vasconcelos E Cruz J.	Pharmaceutics	10.3390/pharmaceutics16050614	2024
	Chemiluminescent duplex analysis using phenoxy-1,2-dioxetane luminophores with color modulation.	Gutkin S, Tannous R, Jaber Q, Fridman M, Shabat D.	Chem Sci	10.1039/d3sc02386a	2023
	Evaluating the Effects of Camellia Sinensis (Green Tea) and Teucrium Polium Extracts on Salivary Streptococcus Mutans Levels in Children.	Sajadi F, Shokrizadeh M, Sharifi M, Aftabi R.	J Dent (Shiraz)	10.30476/dentjods.2021.92379.1640	2023
	Effect of hydroalcoholic extract of whole pomegranate fruit on cariogenic bacteria and its clinical effect on dental plaque formation in 8-10-year-old children.	Mahd MA, Aref P, Emadi F, Javadi F, Kharazi Fard MJ, Tavassoli-Hojjati S.	Dent Res J (Isfahan)	10.4103/drj.drj_173_23	2023
	Comparison of the Intensity of Biofilm Production by Oral Microflora and Its Adhesion on the Surface of Zirconia Produced in Additive and Subtractive Technology: An In Vitro Study.	Frackiewicz W, Pruss A, Krolikowski M, Szymlet P, Sobolewska E.	Materials (Basel)	10.3390/ma17061231	2024
	Evaluation of L-arginine supplement on the growth rate, biofilm formation, and antibiotic susceptibility in Streptococcus mutans.	Vaziriamjad S, Solgi M, Kamarehei F, Nouri F, Taheri M.	Eur J Med Res	10.1186/s40001-022-00735-7	2022
	Antibacterial properties of bioengineered silver nanoparticles from Pastinaca sativa against Enterococcus faecalis biofilms in endodontic therapy.	Didar AA, Ghadimi S, Yousefbeigi A, Farahani P, Bahman Z, Khajeh Salehani H, Asgari Z.	Sci Rep	10.1038/s41598-025-23394-0	2025
	Comparative Evaluation of the Physical and Antimicrobial Properties of Mineral Trioxide Aggregate, Biodentine, and a Modified Fast-Setting Mineral Trioxide Aggregate Without Tricalcium Aluminate: An In Vitro Study.	Ravindran V, Jeevanandan G.	Cureus	10.7759/cureus.42856	2023
	Cellulose Nanocrystals Show Anti-Adherent and Anti-Biofilm Properties against Oral Microorganisms.	Panio A, Ionescu AC, La Ferla B, Zoia L, Savadori P, Tartaglia GM, Brambilla E.	Bioengineering (Basel)	10.3390/bioengineering11040355	2024
	Comparative Evaluation of Antimicrobial Activity and Minimum Inhibitory Concentration of Commercially Available Pediatric Dentifrices: An In Vitro Study.	Dureha R, Navit S, Khan SA, Mathur P.	Int J Clin Pediatr Dent	10.5005/jp-journals-10005-2939	2024
	Combined Antimicrobial Activity of Extracts from Quercus infectoria Galls and Scrophularia striata Aerial Parts for an Anticariogenic Herbal Mouthwash.	Falakdin P, Dastan D, Pourmoslemi S.	J Pharmacopuncture	10.3831/kpi.2023.26.1.44	2023
	Anti-Inflammatory, Antioxidant and Antibacterial Properties of Tomato Skin and Pomegranate Peel Extracts: A Sustainable Approach for Oral Health Care.	Silla A, Punzo A, Bonvicini F, Perillo M, Malaguti M, Lorenzini A, Foltran I, Mercatante D, Mandrioli M, Rodriguez-Estrada MT, Hrelia S, Caliceti C.	Antioxidants (Basel)	10.3390/antiox14010054	2025
	Evaluation of cytotoxicity and antibacterial activity of different pulp capping liners.	Moradi Z, Abbasi M, Bahador A, Yekaninejad MS, Khanghah XM, Hoseini AP, Ranjbar Omrani L.	Biomater Investig Dent	10.1080/26415275.2023.2287019	2023
	Synthesis, Biocidal and Antibiofilm Activities of New Isatin-Quinoline Conjugates against Multidrug-Resistant Bacterial Pathogens along with Their In Silico Screening.	Elmongy EI, Ahmed AAS, El Sayed IET, Fathy G, Awad HM, Salman AU, Hamed MA.	Antibiotics (Basel)	10.3390/antibiotics11111507	2022
	A modified formulation of Zoono GermFree24 antiseptic liquid has enhanced efficacy against biofilms of Staphylococcus aureus and Pseudomonas aeruginosa.	Hale SJM, Lux CA, Kim R, Biswas K, Wagner Mackenzie B, Douglas RG.	Biofouling	10.1080/08927014.2025.2467078	2025
	Sustained antibacterial activity of orthodontic elastomeric ligature ties coated with a novel kombucha-derived bacterial nanocellulose: An in-vitro study.	Eskandari F, Borzou S, Razavian A, Babanouri N, Yousefi K.	PLoS One	10.1371/journal.pone.0292966	2024
	Antibacterial Properties of the Antimicrobial Peptide Gallic Acid-Polyphemusin I (GAPI).	Zhang OL, Niu JY, Yin IX, Yu OY, Mei ML, Chu CH.	Antibiotics (Basel)	10.3390/antibiotics12091350	2023
	Therapeutic Potential of Punica granatum and Isolated Compounds: Evidence-Based Advances to Treat Bacterial Infections.	Mendes PM, Gomes Fontoura GM, Rodrigues LDS, Souza AS, Viana JPM, Fernandes Pereira AL, Dutra RP, Nogueira Ferreira AG, Neto MS, Reis AS, Berretta AA, Monteiro-Neto V, Maciel MCG.	Int J Microbiol	10.1155/2023/4026440	2023
	Antimicrobial effect of different physical and chemical compounds of zinc oxide and graphene oxide added to composite resins.	Farhangian Z, Alaghehmand H, Tashakkorian H, Mokhtarpour F, Davoodabadi A.	Dent Res J (Isfahan)	10.4103/1735-3327.356820	2022
	Thermo-Responsive Hydrogel Containing Microfluidic Chitosan Nanoparticles Loaded with Opuntia ficus-indica Extract for Periodontitis Treatment.	Conte R, Valentino A, De Luca I, Soares Pontes G, Calarco A, Cerruti P.	Int J Mol Sci	10.3390/ijms25179374	2024
	Effect of a Berry Polyphenolic Fraction on Biofilm Formation, Adherence Properties and Gene Expression of Streptococcus mutans and Its Biocompatibility with Oral Epithelial Cells.	Souissi M, Ben Lagha A, Chaieb K, Grenier D.	Antibiotics (Basel)	10.3390/antibiotics10010046	2021
	Applications of Silver Nanoparticles in Pediatric Dentistry: An Overview.	Khubchandani M, Thosar NR, Dangore-Khasbage S, Srivastava R.	Cureus	10.7759/cureus.26956	2022
	In vitro antimicrobial effects of green tea, microwaving, cold boiled water, and chlorhexidine on Streptococcus mutans and Candida albicans on silicone pacifiers.	Hajiahmadi M, Faghri J, Saliminabi Z, Moshkelgosha H, Shayankia A, Heidari F.	Dent Res J (Isfahan)	10.4103/1735-3327.340108	2022
	Sol-gel synthesis of amorphous calcium phosphate nanoparticles in brown rice substrate and assessment of their cytotoxicity and antimicrobial activities.	Beigoli S, Hekmat A, Farzanegan F, Darroudi M.	Avicenna J Phytomed	10.22038/ajp.2021.18930	2022
	Lactobacillus rhamnosus biosurfactant inhibits biofilm formation and gene expression of caries-inducing Streptococcus mutans.	Tahmourespour A, Kasra-Kermanshahi R, Salehi R.	Dent Res J (Isfahan)	10.4103/1735-3327.250968	2019
	Antibacterial effects and cellular mechanisms of iron oxide magnetic nanoparticles coated by piroctone olamine against some cariogenic bacteria.	Ghorbanizadeh S, Karami F, Delfani S, Shakibaie M, Razlansari A, Rezaei F.	Ann Med Surg (Lond)	10.1016/j.amsu.2022.104291	2022
	Comparative Evaluation of Antibacterial Effect of Propolis and Aloe Vera, Xylitol, and Cpp-Acp Gels on Streptococcus mutans and Lactobacillus in Vitro.	Hajiahmadi M, Faghri J, Salehi Z, Heidari F.	Int J Dent	10.1155/2021/5842600	2021
	A Novel Developed Bioactive Composite Resin Containing Silver/Zinc Oxide (Ag/ZnO) Nanoparticles as an Antimicrobial Material against Streptococcus mutans, Lactobacillus, and Candida albicans.	Kachoei M, Divband B, Rahbar M, Esmaeilzadeh M, Ghanizadeh M, Alam M.	Evid Based Complement Alternat Med	10.1155/2021/4743411	2021
	In Vitro Evaluation of Photodynamic Activity of Plant Extracts from Senna Species against Microorganisms of Medical and Dental Interest.	Oliveira AB, Ferrisse TM, Annunzio SR, Franca MGA, Silva MGV, Cavalheiro AJ, Fontana CR, Brighenti FL.	Pharmaceutics	10.3390/pharmaceutics15010181	2023
	Antimicrobial Activity of Silver Nanoparticles Synthesized by the Green Method Using Rhus coriaria L. Extract Against Oral Pathogenic Microorganisms.	Nazemi Salman B, Mohammadi Gheidari M, Yazdi Nejad A, Zeighami H, Mohammadi A, Basir Shabestari S.	Med J Islam Repub Iran	10.47176/mjiri.36.154	2022
Pathogenicity	Iranian propolis efficiently inhibits growth of oral streptococci and cancer cell lines.	Asgharpour F, Moghadamnia AA, Zabihi E, Kazemi S, Ebrahimzadeh Namvar A, Gholinia H, Motallebnejad M, Nouri HR.	BMC Complement Altern Med	10.1186/s12906-019-2677-3	2019
	Effect of endocrine disruptors on bacterial virulence.	Thiroux A, Berjeaud JM, Villeger R, Crepin A.	Front Cell Infect Microbiol	10.3389/fcimb.2023.1292233	2023
	Evaluating the Efficacy of Rose Bengal as a Photosensitizer in Antimicrobial Photodynamic Therapy Against Candida albicans: A Systematic Review.	Fiegler-Rudol J, Lipka B, Kaplon K, Mos M, Skaba D, Kawczyk-Krupka A, Wiench R.	Int J Mol Sci	10.3390/ijms26115034	2025
	Antibacterial properties of an acrylic resin containing curcumin nanoparticles: An in vitro study.	Khamooshi P, Pourhajibagher M, Sodagar A, Bahador A, Ahmadi B, Arab S.	J Dent Res Dent Clin Dent Prospects	10.34172/joddd.2022.032	2022
Pathogenicity	Combinatorial therapy of chitosan hydrogel-based zinc oxide nanocomposite attenuates the virulence of Streptococcus mutans.	Afrasiabi S, Bahador A, Partoazar A.	BMC Microbiol	10.1186/s12866-021-02128-y	2021
	Synthesis, Characterization, and Docking Study of Novel Thioureidophosphonate-Incorporated Silver Nanocomposites as Potent Antibacterial Agents.	El-Tantawy AI, Elmongy EI, Elsaeed SM, Abdel Aleem AAH, Binsuwaidan R, Eisa WH, Salman AU, Elharony NE, Attia NF.	Pharmaceutics	10.3390/pharmaceutics15061666	2023
	The Comparison of Antimicrobial Effect of Nigella sativa Nanoparticle and Chlorhexidine Emulsion on the Most Common Dental Cariogenicic Bacteria.	Nazemi Salman B, Sallah S, Abdi F, Salahi S, Rostamizadeh K, Basir Shabestari S.	Med J Islam Repub Iran	10.47176/mjiri.35.149	2021
	Evaluation of the cell viability and antimicrobial effects of orthodontic bands coated with silver or zinc oxide nanoparticles: An in vitro study.	Bahrami R, Pourhajibagher M, Badiei A, Masaeli R, Tanbakuchi B.	Korean J Orthod	10.4041/kjod22.091	2023
	Oral mucosa and Streptococcus mutans count in the saliva. Does graphene oxide nanoparticle mouthwash have a good effect?	Eshaghi Gorji F, Seyedmajidi M, Asgharpours F, Tashakorian H, Moghadamnia AA, Kazemi S, Alaghehmand H.	Caspian J Intern Med	10.22088/cjim.12.3.342	2021
	Periodontal ligament stem cell-derived exosome-loaded Emodin mediated antimicrobial photodynamic therapy against cariogenic bacteria.	Pourhajibagher M, Bahador A.	BMC Oral Health	10.1186/s12903-024-04062-7	2024
Pathogenicity	New Strategies for Biocontrol of Bacterial Toxins and Virulence: Focusing on Quorum-Sensing Interference and Biofilm Inhibition.	Zhang H, Zhang Z, Li J, Qin G.	Toxins (Basel)	10.3390/toxins15090570	2023
	Study of the Antimicrobial Activity of the Human Peptide SQQ30 against Pathogenic Bacteria.	Di Napoli M, Castagliuolo G, Pio S, Di Nardo I, Russo T, Antonini D, Notomista E, Varcamonti M, Zanfardino A.	Antibiotics (Basel)	10.3390/antibiotics13020145	2024
	A pharmacodynamic study of a new gel containing an extract of Aloe vera and an extract of oak bark for potential treatment of periodontal diseases.	A TN, S ZD.	Ceska Slov Farm		2020
	Novel Chloro-Substituted Salicylanilide Derivatives and Their beta-Cyclodextrin Complexes: Synthesis, Characterization, and Antibacterial Activity.	Ienascu IMC, Cata A, Stefanut MN, Popescu I, Rusu G, Sfirloaga P, Ursu D, Mosoarca C, Dabici A, Danciu C, Muntean D, Pop R.	Biomedicines	10.3390/biomedicines10071740	2022
	Thymus richardii subsp. nitidus (Guss.) Jalas Essential Oil: An Ally against Oral Pathogens and Mouth Health.	Castagliuolo G, Di Napoli M, Vaglica A, Badalamenti N, Antonini D, Varcamonti M, Bruno M, Zanfardino A, Bazan G.	Molecules	10.3390/molecules28124803	2023
	In vitro antimicrobial activity of mineral trioxide aggregate, Biodentine, and calcium-enriched mixture cement against Enterococcus faecalis, Streptococcus mutans, and Candida albicans using the agar diffusion technique.	Esteki P, Jahromi MZ, Tahmourespour A.	Dent Res J (Isfahan)	10.4103/1735-3327.310032	2021
	Evaluation of the biological responses of silver nanoparticles synthesized using Pelargonium x hortorum extract.	Lopez-Ayuso CA, Garcia-Contreras R, Manisekaran R, Figueroa M, Arenas-Arrocena MC, Hernandez-Padron G, Pozos-Guillen A, Acosta-Torres LS.	RSC Adv	10.1039/d3ra00201b	2023
	The antibacterial effect of Magnolia mouthwash on the levels of salivary Streptococcus mutans in dental plaque: a randomized, single-blind, placebo-controlled trial.	Ghorbani F, Haghgoo R, Aramjoo H, Rakhshandeh H, Jamehdar SA, Zare-Bidaki M.	Iran J Microbiol	10.18502/ijm.v13i1.5499	2021
	Efficacy of Ceragenins in Controlling the Growth of Oral Microorganisms: Implications for Oral Hygiene Management.	Czarnowski M, Slowinska M, Sawieljew M, Wnorowska U, Daniluk T, Krol G, Karasinski M, Okla S, Savage PB, Piktel E, Bucki R.	Pharmaceuticals (Basel)	10.3390/ph17020204	2024
	Contamination of Low Frictional Elastomeric Ligatures by Streptococcus mutans: A Prospective RT-PCR and AFM Study.	Dagdeviren C, Gulec A, Eksi F, Saglam M, Kahraman M.	Turk J Orthod	10.5152/turkjorthod.2021.20091	2021
	Antimicrobial effects and mechanical properties of poly(methyl methacrylate) as an orthodontic acrylic resin containing Curcumin-Nisin-poly(L-lactic acid) nanoparticle: an in vitro study.	Pourhajibagher M, Noroozian M, Ahmad Akhoundi MS, Bahador A.	BMC Oral Health	10.1186/s12903-022-02197-z	2022
	Biological and mechanical properties of a self-curing acrylic resin enriched with AgNPs as a proposal for orthopedic aparatology.	Lopez-Ayuso CA, Garcia-Contreras R, Manisekaran R, Figueroa M, Rangel-Grimaldo M, Jacome M, Dominguez-Perez RA, Lopez-Morales S, Cristians S, Acosta-Torres LS.	Nanoscale Adv	10.1039/d4na00846d	2025
	Optimization of antimicrobial efficiency of silver nanoparticles against three oral microorganisms in irreversible hydrocolloid impressions.	Jafari A, Fard RMN, Shahabi S, Abbasi F, Shahedin GJ, Bakhtiari R.	Iran J Microbiol	10.18502/ijm.v13i6.8091	2021
Pathogenicity	Influence of Physical Dimension and Morphological-Dependent Antibacterial Characteristics of ZnO Nanoparticles Coated on Orthodontic NiTi Wires.	Gholami M, Esmaeilzadeh M, Kachoei Z, Kachoei M, Divband B.	Biomed Res Int	10.1155/2021/6397698	2021
	Disinfection and Biocompatibility of Titanium Surfaces Treated with Glycine Powder Airflow and Triple Antibiotic Mixture: An In Vitro Study.	Alovisi M, Carossa M, Mandras N, Roana J, Costalonga M, Cavallo L, Pira E, Putzu MG, Bosio D, Roato I, Mussano F, Scotti N.	Materials (Basel)	10.3390/ma15144850	2022
	Degradation of Polylactide and Polycaprolactone as a Result of Biofilm Formation Assessed under Experimental Conditions Simulating the Oral Cavity Environment.	Lysik D, Deptula P, Chmielewska S, Bucki R, Mystkowska J.	Materials (Basel)	10.3390/ma15207061	2022
	Quorum quenching of Streptococcus mutans via the nano-quercetin-based antimicrobial photodynamic therapy as a potential target for cariogenic biofilm.	Pourhajibagher M, Alaeddini M, Etemad-Moghadam S, Rahimi Esboei B, Bahrami R, Miri Mousavi RS, Bahador A.	BMC Microbiol	10.1186/s12866-022-02544-8	2022
	Comparative Evaluation of Antimicrobial Efficacy of Herbal Formulations of Septilin and Triphala with Conventional 2% Chlorhexidine on Root Canal and Oral Commensal Bacteria using Kirby Bauer Method: An in-vitro Study.	Ahmed S, Shahnawaz K, Mandal TK, Ghafir M, Gummaluri SS, Vishal G.	Contemp Clin Dent	10.4103/ccd.ccd_423_21	2022
	The antibacterial effects of vitamin D3 against mutans streptococci: an in vitro study.	Almoudi MMM, Hussein AS, Abu Hassan MI, Al-Talib H, Khan HBSG, Nazli SAB, Effandy NAEB.	Eur Oral Res	10.26650/eor.20210119	2021
	Characterization and Physical and Biological Properties of Tissue Conditioner Incorporated with Carum copticum L.	Hejazi M, Zareshahrabadi Z, Ashayeri S, Saharkhiz MJ, Iraji A, Alishahi M, Zomorodian K.	Biomed Res Int	10.1155/2021/5577760	2021
Pathogenicity	Propolis nanoparticle enhances the potency of antimicrobial photodynamic therapy against Streptococcus mutans in a synergistic manner.	Afrasiabi S, Pourhajibagher M, Chiniforush N, Bahador A.	Sci Rep	10.1038/s41598-020-72119-y	2020
	Targeted antimicrobial self-assembly peptide hydrogel with in situ bio-mimic remineralization for caries management.	Zhou L, Liu Q, Fang Z, Li QL, Wong HM.	Bioact Mater	10.1016/j.bioactmat.2024.10.022	2025
Biotechnology	Antioxidant, Antimicrobial Activities and Fatty Acid Compositions of Wild Berberis spp. by Different Techniques Combined with Chemometrics (PCA and HCA).	Gidik B.	Molecules	10.3390/molecules26247448	2021
	Synthesis and Characterization of Fluoridated Silver Nanoparticles and Their Potential as a Non-Staining Anti-Caries Agent.	Yin IX, Zhao IS, Mei ML, Mei ML, Lo ECM, Tang J, Li Q, So LY, Chu CH.	Int J Nanomedicine	10.2147/ijn.s243202	2020
	Antibacterial coating of tooth surface with ion-releasing pre-reacted glass-ionomer (S-PRG) nanofillers.	Mayumi K, Miyaji H, Miyata S, Nishida E, Furihata T, Kanemoto Y, Sugaya T, Shitomi K, Akasaka T.	Heliyon	10.1016/j.heliyon.2021.e06147	2021
	Antimicrobial effect of Pistacia atlantica leaf extract.	Ali Roozegar M, Azizi Jalilian F, Reza Havasian M, Panahi J, Pakzad I.	Bioinformation	10.6026/97320630012019	2016
	Experimental Evaluation of the Effect of Zinc Salt on Inhibition of Streptococcus mutans.	Lavaee F, Ghapanchi J, Motamedifar M, Sharifzade Javidi M.	J Dent (Shiraz)		2018
	Evaluation of Antibacterial Effects of Fissure Sealants Containing Chitosan Nanoparticles.	Hashemi Kamangar SS, Zareian H, Bahador A, Pourhajibagher M, Bashareh Z, Valizadeh S.	Int J Dent	10.1155/2021/8975948	2021
	Cytotoxicity and Antibacterial Activity of Toothpastes and Mouthwashes Available in the Iranian Market.	Shahidi Z, Tavakol Davani S, Noori F, Hasani Tabatabaei M, Sodeif F, Etemadi A, Chiniforush N, Moradi Z.	Front Dent	10.18502/fid.v18i7.5650	2021
	Assessment of cytotoxic and antimicrobial activities of two components of Cymbopogon citratus essential oil.	Chaves-Quiros C, Usuga-Usuga JS, Morales-Uchima SM, Tofino-Rivera AP, Tobon-Arroyave SI, Martinez-Pabon MC.	J Clin Exp Dent	10.4317/jced.56863	2020
	TEGDMA-Functionalized Dicalcium Phosphate Dihydrate Resin-Based Composites Prevent Secondary Caries in an In Vitro Biofilm Model.	Ionescu AC, Hahnel S, Chiari MDS, Konig A, Delvecchio P, Braga RR, Zambelli V, Brambilla E.	J Funct Biomater	10.3390/jfb13040232	2022
	Effect of Prebiotics-Enhanced Probiotics on the Growth of Streptococcus mutans.	Nunpan S, Suwannachart C, Wayakanon K.	Int J Microbiol	10.1155/2019/4623807	2019
	Anti-Oral Pathogens of Tecoma stans (L.) and Cassia javanica (L.) Flower Volatile Oils in Comparison with Chlorhexidine in Accordance with Their Folk Medicinal Uses.	Mohammed HA, Abdel-Aziz MM, Hegazy MM.	Medicina (Kaunas)	10.3390/medicina55060301	2019
	Berberine-Functionalized Bismuth-Doped Carbon Dots in a Pathogen-Responsive Hydrogel System: A Multifaceted Approach to Combating Periodontal Diseases.	Li X, Huang R, Li P, Tang FK, He J, Sun H, Wang X, Wang M, Lan X, Wang X, Wong SSW, Jin L, Leung KC, Wong HM, Wang S, Guo L, Ding PH, Yu X.	ACS Nano	10.1021/acsnano.5c00561	2025
	Evaluation of biofilm removal activity of Quercus infectoria galls against Streptococcus mutans.	Mohammadi-Sichani M, Karbasizadeh V, Dokhaharani SC.	Dent Res J (Isfahan)	10.4103/1735-3327.174708	2016
	Cell Toxicity and inhibitory effects of Cyperus rotundus extract on Streptococcus mutans, Aggregatibacter actinomycetemcomitans and Candida albicans.	Khojaste M, Yazdanian M, Tahmasebi E, Tahmasebi E, Shokri M, Houshmand B, Houshmand B, Shahbazi R.	Eur J Transl Myol	10.4081/ejtm.2018.7917	2018
	Investigating the antibacterial effects of some Lactobacillus, Bifidobacterium and acetobacter strains killed by different methods on Streptococcus mutans and Escherichia coli.	Safari MS, Keyhanfar M, Shafiei R.	Mol Biol Res Commun	10.22099/mbrc.2019.33582.1399	2019
	Influence of Curing Time on the Microbiological Behavior of Bulk-Fill Nanohybrid Resin Composites.	Ionescu AC, Comba A, Brambilla E, Ilie N, Breschi L, Cadenaro M, Scotti N.	Polymers (Basel)	10.3390/polym13172948	2021
	Antibacterial and Antibiofilm Photodynamic Activities of Lysozyme-Au Nanoclusters/Rose Bengal Conjugates.	Okamoto I, Miyaji H, Miyata S, Shitomi K, Sugaya T, Ushijima N, Akasaka T, Enya S, Saita S, Kawasaki H.	ACS Omega	10.1021/acsomega.1c00838	2021
	Mouthwash Formulation Co-Delivering Quercetin and Mint Oil in Liposomes Improved with Glycol and Ethanol and Tailored for Protecting and Tackling Oral Cavity.	Castangia I, Manconi M, Manconi M, Allaw M, Perra M, Orru G, Fais S, Scano A, Escribano-Ferrer E, Ghavam M, Rezvani M, Manca ML.	Antioxidants (Basel)	10.3390/antiox11020367	2022
	Anticaries Agent Based on Silver Nanoparticles and Fluoride: Characterization and Biological and Remineralizing Effects-An In Vitro Study.	Favaro JC, Detomini TR, Maia LP, Poli RC, Guiraldo RD, Lopes MB, Berger SB.	Int J Dent	10.1155/2022/9483589	2022
Pathogenicity	A broad-spectrum bactericidal lipopeptide with anti-biofilm properties.	Meir O, Zaknoon F, Cogan U, Mor A.	Sci Rep	10.1038/s41598-017-02373-0	2017
	Improving the Hydrophobicity of Plasticized Polyvinyl Chloride for Use in an Endotracheal Tube	Marcut L, Mohan A, Corneschi I, Grosu E, Paltanea G, Avram I, Badaluta A, Vasilievici G, Nicolae C, Ditu L.	Materials (Basel)		2023
Pathogenicity	Surface Modification by Nano-Structures Reduces Viable Bacterial Biofilm in Aerobic and Anaerobic Environments.	Ya'ari S, Halperin-Sternfeld M, Rosin B, Adler-Abramovich L.	Int J Mol Sci	10.3390/ijms21197370	2020
	In vitro Comparison of Antimicrobial Activity of Conventional Fluoride Varnishes Containing Xylitol and Casein Phosphopeptide-Amorphous Calcium Phosphate.	Jafari K, Hekmatfar S, Fereydunzadeh M.	J Int Soc Prev Community Dent	10.4103/jispcd.jispcd_67_18	2018
	Antibacterial Activities of Herbal Toothpastes Combined with Essential Oils against Streptococcus mutans.	Karadaglioglu OI, Ulusoy N, Baser KHC, Hanoglu A, Sik I.	Pathogens	10.3390/pathogens8010020	2019
	Evaluation of Anti-oxidant and Anti-biofilm Activities of Biogenic Surfactants Derived from Bacillus amyloliquefaciens and Pseudomonas aeruginosa.	Abdollahi S, Tofighi Z, Babaee T, Shamsi M, Rahimzadeh G, Rezvanifar H, Saeidi E, Mohajeri Amiri M, Saffari Ashtiani Y, Samadi N.	Iran J Pharm Res	10.22037/ijpr.2020.1101033	2020
	Using Copper-Doped Mesoporous Bioactive Glass Nanospheres to Impart Anti-Bacterial Properties to Dental Composites.	Munir A, Marovic D, Nogueira LP, Simm R, Naemi AO, Landro SM, Helgerud M, Zheng K, Par M, Taubock TT, Attin T, Tarle Z, Boccaccini AR, Haugen HJ.	Pharmaceutics	10.3390/pharmaceutics14102241	2022
	Fabrication of Multilayered Biofunctional Material with an Enamel-like Structure.	Zhang YY, Li QL, Wong HM.	Int J Mol Sci	10.3390/ijms232213810	2022
	Antimicrobial Effect of Different Sizes of Nano Zinc Oxide on Oral Microorganisms.	Mirhosseini F, Amiri M, Daneshkazemi A, Zandi H, Javadi ZS.	Front Dent	10.18502/fid.v16i2.1361	2019
	Effect of sodium chloride on gene expression of Streptococcus mutans and zeta potential of demineralized dentin.	Nagavi-Alhoseiny AA, Torshabi M, Rasoulianboroujeni M, Tayebi L, Tabatabaei FS.	J Oral Biol Craniofac Res	10.1016/j.jobcr.2018.08.002	2019
	Evaluation of Antibacterial Effect of Propolis and its Application in Mouthwash Production.	Nazeri R, Ghaiour M, Abbasi S.	Front Dent	10.18502/fid.v16i1.1103	2019
Pathogenicity	Surface roughness, plaque accumulation, and cytotoxicity of provisional restorative materials fabricated by different methods.	Giti R, Dabiri S, Motamedifar M, Derafshi R.	PLoS One	10.1371/journal.pone.0249551	2021
	Comparison of Biological Properties of Two Medicinal Extracts of the Tehuacan-Cuicatlan Valley.	Martinez-Elizalde KS, Rodriguez-Monroy MA, Flores CM, Flores CM, Hernandez-Portilla LB, Barbosa-Cabrera E, Canales-Martinez MM.	Evid Based Complement Alternat Med	10.1155/2018/4918090	2018
	Bacillus licheniformis: A Producer of Antimicrobial Substances, including Antimycobacterials, Which Are Feasible for Medical Applications.	Shleeva MO, Kondratieva DA, Kaprelyants AS.	Pharmaceutics	10.3390/pharmaceutics15071893	2023
Pathogenicity	Effect of Silver Nitrate and Sodium Fluoride with Tri-Calcium Phosphate on Streptococcus mutans and Demineralised Dentine.	Yu OY, Zhao IS, Mei ML, Lo EC, Chu CH.	Int J Mol Sci	10.3390/ijms19051288	2018
	Antibacterial Properties of Copper Oxide Nanoparticles (Review).	Gudkov SV, Burmistrov DE, Fomina PA, Validov SZ, Kozlov VA.	Int J Mol Sci	10.3390/ijms252111563	2024
	Phytochemical and biological activities of some Iranian medicinal plants.	Dini S, Chen Q, Fatemi F, Asri Y.	Pharm Biol	10.1080/13880209.2022.2046112	2022
	Molecular Diagnosis of Bacterial Definite Infective Endocarditis by Real-Time Polymerase Chain Reaction.	Faraji R, Behjati-Ardakani M, Faraji N, Moshtaghioun SM, Kalantar SM, Pedarzadeh A, Zandi H, Sarebanhassanabadi M, Ahmadi N, Dehghani Firoozabadi A.	Cardiol Res	10.14740/cr687w	2018
	Design, Synthesis and Biological Evaluation of Lophanic Acid Derivatives as Antifungal and Antibacterial Agents.	Yu X, Song X, Zhang Y, Yang Y, Ye J, Liu Y, Pan L, Zhang H.	Molecules	10.3390/molecules27206836	2022
	Chemical and Antimicrobial Characterization of Mentha piperita L. and Rosmarinus officinalis L. Essential Oils and In Vitro Potential Cytotoxic Effect in Human Colorectal Carcinoma Cells.	Dolghi A, Coricovac D, Dinu S, Pinzaru I, Dehelean CA, Grosu C, Chioran D, Merghes PE, Sarau CA.	Molecules	10.3390/molecules27186106	2022
Pathogenicity	Subinhibitory concentrations of triclosan promote Streptococcus mutans biofilm formation and adherence to oral epithelial cells.	Bedran TB, Grignon L, Spolidorio DP, Grenier D.	PLoS One	10.1371/journal.pone.0089059	2014
	The Proteome of Community Living Candida albicans Is Differentially Modulated by the Morphologic and Structural Features of the Bacterial Cohabitants.	Truong T, Pang LM, Rajan S, Wong SSW, Fung YME, Samaranayake L, Seneviratne CJ.	Microorganisms	10.3390/microorganisms8101541	2020
	Citrus limon Extract Loaded in Vesicular Systems for the Protection of Oral Cavity.	Manconi M, Manca ML, Caddeo C, Sarais G, Palmieri A, D'Hallewin G, Fadda AM.	Medicines (Basel)	10.3390/medicines5040108	2018
	Comparison of antimicrobial effects of titanium tetrafluoride, chlorhexidine, xylitol and sodium fluoride on streptococcus mutans: An in-vitro study.	Eskandarian T, Motamedifar M, Arasteh P, Eghbali SS, Adib A, Abdoli Z.	Electron Physician	10.19082/4042	2017
Pathogenicity	Surface-modified nanoparticles as anti-biofilm filler for dental polymers.	Zaltsman N, Ionescu AC, Weiss EI, Brambilla E, Beyth S, Beyth N.	PLoS One	10.1371/journal.pone.0189397	2017
	Antimicrobial Activity of Peganum Harmala L. on Streptococcus mutans Compared to 0.2% Chlorhexidine.	Motamedifar M, Khosropanah H, Dabiri S.	J Dent (Shiraz)		2016
	Mechanical, antibacterial and bond strength properties of nano-titanium-enriched glass ionomer cement.	Garcia-Contreras R, Scougall-Vilchis RJ, Contreras-Bulnes R, Sakagami H, Morales-Luckie RA, Nakajima H.	J Appl Oral Sci	10.1590/1678-775720140496	2015
	Antimicrobial Efficacy of Silver Nanoparticles against Candida Albicans.	Adam RZ, Khan SB.	Materials (Basel)	10.3390/ma15165666	2022
	A systematic review on antibacterial activity of zinc against Streptococcus mutans.	Almoudi MM, Hussein AS, Abu Hassan MI, Mohamad Zain N.	Saudi Dent J	10.1016/j.sdentj.2018.06.003	2018
	Evaluation of the Effect of Propolis Nanoparticles on Antimicrobial Properties and Shear Bond Strength of Orthodontic Composite Bonded to Bovine Enamel.	Sodagar A, Akhavan A, Arab S, Bahador A, Pourhajibagher M, Soudi A.	Front Dent	10.18502/fid.v16i2.1360	2019
	Evaluation of antibacterial efficiency of chitosan and chitosan nanoparticles on cariogenic streptococci: an in vitro study.	Aliasghari A, Rabbani Khorasgani M, Vaezifar S, Rahimi F, Younesi H, Khoroushi M.	Iran J Microbiol		2016
	Chemical Composition and Antimicrobial Activities of the Essential Oil From Salvia mirzayanii Leaves.	Zomorodian K, Moein M, Pakshir K, Karami F, Sabahi Z.	J Evid Based Complementary Altern Med	10.1177/2156587217717414	2017
Pathogenicity	In vitro effect photodynamic therapy with differents photosensitizers on cariogenic microorganisms.	Soria-Lozano P, Gilaberte Y, Paz-Cristobal MP, Perez-Artiaga L, Lampaya-Perez V, Aporta J, Perez-Laguna V, Garcia-Luque I, Revillo MJ, Rezusta A.	BMC Microbiol	10.1186/s12866-015-0524-3	2015
	Down-Regulation of Glycosyl Transferase Genes in Streptococcus Mutans by Punica Granatum L. Flower and Rhus Coriaria L. Fruit Water Extracts.	Vahid-Dastjerdi E, Monadi E, Khalighi HR, Torshabi M.	Iran J Pharm Res		2016
	Substituted Nano-Hydroxyapatite Toothpastes Reduce Biofilm Formation on Enamel and Resin-Based Composite Surfaces.	Ionescu AC, Cazzaniga G, Ottobelli M, Garcia-Godoy F, Brambilla E.	J Funct Biomater	10.3390/jfb11020036	2020
	In Vitro Antimicrobial Activity and Effect on Biofilm Production of a White Grape Juice (Vitis vinifera) Extract.	Filocamo A, Bisignano C, Mandalari G, Navarra M.	Evid Based Complement Alternat Med	10.1155/2015/856243	2015
	Determination of the antioxidant, antimicrobial and anticancer properties of the honey phenolic extract of five different regions of Bingöl province.	Kaya B, Yildirim A.	J Food Sci Technol	10.1007/s13197-020-04783-x	2021
Metabolism	The Ps and Qs of alarmone synthesis in Staphylococcus aureus.	Yang N, Xie S, Tang NY, Choi MY, Wang Y, Watt RM.	PLoS One	10.1371/journal.pone.0213630	2019
	Copper-containing nanoparticles: Mechanism of antimicrobial effect and application in dentistry-a narrative review.	Ma X, Zhou S, Xu X, Du Q.	Front Surg	10.3389/fsurg.2022.905892	2022
	A comparative in vitro efficacy of conventional rotatory and chemomechanical caries removal: Influence on cariogenic flora, microhardness, and residual composition.	Garcia-Contreras R, Scougall-Vilchis RJ, Contreras-Bulnes R, Sakagami H, Morales-Luckie RA, Nakajima H.	J Conserv Dent	10.4103/0972-0707.144588	2014
Pathogenicity	Enhanced reduction of polymicrobial biofilms on the orthodontic brackets and enamel surface remineralization using zeolite-zinc oxide nanoparticles-based antimicrobial photodynamic therapy.	Pourhajibagher M, Bahador A.	BMC Microbiol	10.1186/s12866-021-02324-w	2021
	In vitro comparison of antimicrobial activity of aqueous decoction of Coriandrum sativum, and Dentol Drop with chlorhexidine on Streptococcus mutans.	Moradian H, Bazargani A, Rafiee A, Nazarialam A.	Iran J Microbiol		2013
	Fibrinogen-induced streptococcus mutans biofilm formation and adherence to endothelial cells.	Bedran TB, Azelmat J, Spolidorio DP, Grenier D.	Biomed Res Int	10.1155/2013/431465	2013
	Antimicrobial photodynamic activity and cytocompatibility of Au₂₅(Capt)₁₈ clusters photoexcited by blue LED light irradiation.	Miyata S, Miyaji H, Kawasaki H, Yamamoto M, Nishida E, Takita H, Akasaka T, Ushijima N, Iwanaga T, Sugaya T.	Int J Nanomedicine	10.2147/ijn.s131602	2017
	Photoactivation of Curcumin Doped Poly-Lactic-Co-Glycolic Acid Nanoparticles in Rat Model with Fixed Orthodontic Appliances.	Ghorbanpour S, Pourhajibagher M, Noroozian M, Ghaffari H, Bahador A.	ScientificWorldJournal	10.1155/2022/3613345	2022
Pathogenicity	The spherical nanoparticle-encapsulated chlorhexidine enhances anti-biofilm efficiency through an effective releasing mode and close microbial interactions.	Li X, Wong CH, Ng TW, Zhang CF, Leung KC, Jin L.	Int J Nanomedicine	10.2147/ijn.s105681	2016
	Rapid synthesis of bismuth-organic frameworks as selective antimicrobial materials against microbial biofilms.	Huang R, Zhou Z, Lan X, Tang FK, Cheng T, Sun H, Cham-Fai Leung K, Li X, Jin L.	Mater Today Bio	10.1016/j.mtbio.2022.100507	2023
	Sustained antibacterial coating with graphene oxide ultrathin film combined with cationic surface-active agents in a wet environment.	Miyaji H, Kanemoto Y, Hamamoto A, Shitomi K, Nishida E, Kato A, Sugaya T, Tanaka S, Aikawa N, Kawasaki H, Gohda S, Ono H.	Sci Rep	10.1038/s41598-022-21205-4	2022
	The effect of antimicrobial photodynamic therapy with radachlorin and toluidine blue on streptococcus mutans: an in vitro study.	Vahabi S, Fekrazad R, Ayremlou S, Taheri S, Zangeneh N.	J Dent (Tehran)		2011
	Thermostable Heptaplex PCR Assay for the Detection of Six Respiratory Bacterial Pathogens.	Nik Zuraina NMN, Goni MD, Amalina KN, Hasan H, Mohamad S, Suraiya S.	Diagnostics (Basel)	10.3390/diagnostics11050753	2021
Pathogenicity	Synthesis and antimicrobial activity of chiral quaternary N-spiro ammonium bromides with 3',4'-dihydro-1'H-spiro[isoindoline-2,2'-isoquinoline] skeleton.	Bielawski K, Leszczynska K, Kaluza Z, Bielawska A, Michalak O, Daniluk T, Staszewska-Krajewska O, Czajkowska A, Pawlowska N, Gornowicz A.	Drug Des Devel Ther	10.2147/dddt.s133250	2017
	Inhibition of Cariogenic Plaque Formation on Root Surface with Polydopamine-Induced-Polyethylene Glycol Coating.	Mei ML, Li QL, Chu CH.	Materials (Basel)	10.3390/ma9060414	2016
	Isolation of Novel Probiotic Lactobacillus and Enterococcus Strains From Human Salivary and Fecal Sources.	Bazireh H, Shariati P, Azimzadeh Jamalkandi S, Ahmadi A, Boroumand MA.	Front Microbiol	10.3389/fmicb.2020.597946	2020
	Antibacterial Effect of Hydroalcoholic Extract of Punica granatum Linn. Petal on Common Oral Microorganisms.	Hajifattahi F, Moravej-Salehi E, Taheri M, Mahboubi A, Kamalinejad M.	Int J Biomater	10.1155/2016/8098943	2016
	In-vitro Comparison of the Antimicrobial Properties of Glass Ionomer Cements with Zinc Phosphate Cements.	Vahid Dastjerdie E, Oskoui M, Sayanjali E, Tabatabaei FS.	Iran J Pharm Res		2012
	Adherence of Streptococcus mutans and Candida albicans to different bracket materials.	Rammohan SN, Juvvadi SR, Gandikota CS, Challa P, Manne R, Mathur A.	J Pharm Bioallied Sci	10.4103/0975-7406.100206	2012
	Phytochemical Profiling and Biological Activities of Quercus sp. Galls (Oak Galls): A Systematic Review of Studies Published in the Last 5 Years.	Banc R, Rusu ME, Filip L, Popa DS.	Plants (Basel)	10.3390/plants12223873	2023
Pathogenicity	Nanoparticle-encapsulated chlorhexidine against oral bacterial biofilms.	Seneviratne CJ, Leung KC, Wong CH, Lee SF, Li X, Leung PC, Lau CB, Wat E, Jin L.	PLoS One	10.1371/journal.pone.0103234	2014
	The Prophylactic Effect of Probiotic Enterococcus lactis IW5 against Different Human Cancer Cells.	Nami Y, Haghshenas B, Haghshenas M, Abdullah N, Yari Khosroushahi A.	Front Microbiol	10.3389/fmicb.2015.01317	2015
	Antimicrobial Effect of Thymus capitatus and Citrus limon var. pompia as Raw Extracts and Nanovesicles.	Pinna R, Filigheddu E, Juliano C, Palmieri A, Manconi M, D'hallewin G, Petretto G, Maioli M, Caddeo C, Manca ML, Solinas G, Bortone A, Campanella V, Milia E.	Pharmaceutics	10.3390/pharmaceutics11050234	2019
	Terpenes and terpenoids as main bioactive compounds of essential oils, their roles in human health and potential application as natural food preservatives.	Masyita A, Mustika Sari R, Dwi Astuti A, Yasir B, Rahma Rumata N, Emran TB, Nainu F, Simal-Gandara J.	Food Chem X	10.1016/j.fochx.2022.100217	2022
	Effect of Silver Diamine Fluoride and Potassium Iodide Treatment on Secondary Caries Prevention and Tooth Discolouration in Cervical Glass Ionomer Cement Restoration.	Zhao IS, Mei ML, Burrow MF, Lo EC, Chu CH.	Int J Mol Sci	10.3390/ijms18020340	2017
	An enamel-inspired bioactive material with multiscale structure and antibacterial adhesion property.	Wong HM, Zhang YY, Li QL.	Bioact Mater	10.1016/j.bioactmat.2021.05.035	2022
	Antimicrobial and Antioxidant Activities of Pycnocycla spinosa Extracts.	Mahboubi M, Taghizadeh M, Kazempour N.	Jundishapur J Nat Pharm Prod	10.17795/jjnpp-13859	2014
Pathogenicity	Caries arresting effect of silver diamine fluoride on dentine carious lesion with S. mutans and L. acidophilus dual-species cariogenic biofilm.	Mei ML, Mei ML, Chu CH, Low KH, Che CM, Lo EC.	Med Oral Patol Oral Cir Bucal	10.4317/medoral.18831	2013
	Essential Oils as Antimicrobial Agents-Myth or Real Alternative?	Winska K, Maczka W, Lyczko J, Grabarczyk M, Czubaszek A, Szumny A, Szumny A.	Molecules	10.3390/molecules24112130	2019
	Optimization of Ultrasonic Extraction of Nutraceutical and Pharmaceutical Compounds from Bee Pollen with Deep Eutectic Solvents Using Response Surface Methodology.	Celik S, Kutlu N, Gercek YC, Bayram S, Pandiselvam R, Bayram NE.	Foods	10.3390/foods11223652	2022
	Biochemical Activities of Iranian Cymbopogon olivieri (Boiss) Bor. Essential Oil.	Mahboubi M, Kazempour N.	Indian J Pharm Sci	10.4103/0250-474x.107071	2012
	Antibacterial activity of endemic Satureja Khuzistanica Jamzad essential oil against oral pathogens.	Seghatoleslami S, Samadi N, Salehnia A, Azimi S.	Iran Endod J		2009
Pathogenicity	Effect of lactoperoxidase on the antimicrobial effectiveness of the thiocyanate hydrogen peroxide combination in a quantitative suspension test.	Welk A, Meller Ch, Schubert R, Schwahn Ch, Kramer A, Below H.	BMC Microbiol	10.1186/1471-2180-9-134	2009
	Chemical composition and antimicrobial activities of essential oil of nepeta cataria L. Against common causes of oral infections.	Zomorodian K, Saharkhiz MJ, Rahimi MJ, Shariatifard S, Pakshir K, Khashei R.	J Dent (Tehran)		2013
Pathogenicity	Antimicrobial activity of Chinese medicine herbs against common bacteria in oral biofilm. A pilot study.	Wong RW, Hagg U, Samaranayake L, Yuen MK, Seneviratne CJ, Kao R.	Int J Oral Maxillofac Surg	10.1016/j.ijom.2010.02.024	2010
	Mutans streptococci genetic strains in children with severe early childhood caries: follow-up study at one-year post-dental rehabilitation therapy.	Palmer EA, Vo A, Hiles SB, Peirano P, Chaudhry S, Trevor A, Kasimi I, Pollard J, Kyles C, Leo M, Wilmot B, Engle J, Peterson J, Maier T, Machida CA.	J Oral Microbiol	10.3402/jom.v4i0.19530	2012
	Total phenolic, total flavonoids, antioxidant and antimicrobial activities of scrophularia striata boiss extracts.	Mahboubi M, Kazempour N, Boland Nazar AR.	Jundishapur J Nat Pharm Prod		2013
	Synthesis and characterization of antibacterial dental monomers and composites.	Xu X, Wang Y, Liao S, Wen ZT, Fan Y.	J Biomed Mater Res B Appl Biomater	10.1002/jbm.b.32683	2012
Pathogenicity	Antibacterial activity of the human host defence peptide LL-37 and selected synthetic cationic lipids against bacteria associated with oral and upper respiratory tract infections.	Leszczynska K, Namiot D, Byfield FJ, Cruz K, Zendzian-Piotrowska M, Fein DE, Savage PB, Diamond S, McCulloch CA, Janmey PA, Bucki R.	J Antimicrob Chemother	10.1093/jac/dks434	2013
Enzymology	Rapid detection of Gram-positive organisms by use of the Verigene Gram-positive blood culture nucleic acid test and the BacT/Alert Pediatric FAN system in a multicenter pediatric evaluation.	Sullivan KV, Turner NN, Roundtree SS, Young S, Brock-Haag CA, Lacey D, Abuzaid S, Blecker-Shelly DL, Doern CD.	J Clin Microbiol	10.1128/jcm.01224-13	2013
	Antimicrobial Activity and Chemical Composition of Essential Oils from Verbenaceae Species Growing in South America.	Perez Zamora CM, Torres CA, Nunez MB.	Molecules	10.3390/molecules23030544	2018
	Filifactor alocis--involvement in periodontal biofilms.	Schlafer S, Riep B, Griffen AL, Petrich A, Hubner J, Berning M, Friedmann A, Gobel UB, Moter A.	BMC Microbiol	10.1186/1471-2180-10-66	2010
Genetics	Children with severe early childhood caries: pilot study examining mutans streptococci genotypic strains after full-mouth caries restorative therapy.	Palmer EA, Nielsen T, Peirano P, Nguyen AT, Vo A, Nguyen A, Jackson S, Finlayson T, Sauerwein R, Marsh K, Edwards I, Wilmot B, Engle J, Peterson J, Maier T, Machida CA.	Pediatr Dent		2012
Phylogeny	PCR for detection and identification of Abiotrophia spp.	Roggenkamp A, Leitritz L, Baus K, Falsen E, Heesemann J.	J Clin Microbiol	10.1128/jcm.36.10.2844-2846.1998	1998
Phylogeny	Are putative periodontal pathogens reliable diagnostic markers?	Riep B, Edesi-Neuss L, Claessen F, Skarabis H, Ehmke B, Flemmig TF, Bernimoulin JP, Gobel UB, Moter A.	J Clin Microbiol	10.1128/jcm.01387-08	2009
Enzymology	Fluorescent In situ hybridization allows rapid identification of microorganisms in blood cultures.	Kempf VA, Trebesius K, Autenrieth IB.	J Clin Microbiol	10.1128/jcm.38.2.830-838.2000	2000
Enzymology	A sensitive, specific, and cost-effective multiplex reverse transcriptase-PCR assay for the detection of seven common respiratory viruses in respiratory samples.	Syrmis MW, Whiley DM, Thomas M, Mackay IM, Williamson J, Siebert DJ, Nissen MD, Sloots TP.	J Mol Diagn	10.1016/s1525-1578(10)60500-4	2004
	Length polymorphisms in tRNA intergenic spacers detected by using the polymerase chain reaction can distinguish streptococcal strains and species.	McClelland M, Petersen C, Welsh J.	J Clin Microbiol	10.1128/jcm.30.6.1499-1504.1992	1992
Phylogeny	Comparison of phenotypic characteristics, DNA-DNA hybridization results, and results with a commercial rapid biochemical and enzymatic reaction system for identification of viridans group streptococci.	Kikuchi K, Enari T, Totsuka K, Shimizu K.	J Clin Microbiol	10.1128/jcm.33.5.1215-1222.1995	1995
	Characterization of Scardovia wiggsiae Biofilm by Original Scanning Electron Microscopy Protocol.	Bossu M, Selan L, Artini M, Relucenti M, Familiari G, Papa R, Vrenna G, Spigaglia P, Barbanti F, Salucci A, Giorgio GD, Rau JV, Polimeni A.	Microorganisms	10.3390/microorganisms8060807	2020
	In vitro antibacterial activity of different pulp capping materials.	Poggio C, Beltrami R, Colombo M, Ceci M, Dagna A, Chiesa M.	J Clin Exp Dent	10.4317/jced.52401	2015
	Biological and antibacterial properties of a new silver fiber post: In vitro evaluation.	Poggio C, Trovati F, Ceci M, Chiesa M, Colombo M, Pietrocola G.	J Clin Exp Dent	10.4317/jced.53464	2017
	Microbial Biofilm Decontamination on Dental Implant Surfaces: A Mini Review.	Dhaliwal JS, Abd Rahman NA, Ming LC, Dhaliwal SKS, Knights J, Albuquerque Junior RF.	Front Cell Infect Microbiol	10.3389/fcimb.2021.736186	2021
	Cytocompatibility and antibacterial properties of capping materials.	Poggio C, Arciola CR, Beltrami R, Monaco A, Dagna A, Lombardini M, Visai L.	ScientificWorldJournal	10.1155/2014/181945	2014
	Biological and chemical-physical properties of root-end filling materials: A comparative study.	Ceci M, Beltrami R, Chiesa M, Colombo M, Poggio C.	J Conserv Dent	10.4103/0972-0707.153058	2015
	Anti-adherence and anti-bacterial activities of Pistacia atlantica resin extract against strongly adherent Streptococcus mutans strains.	Tahmourespour A, Aminzadeh A, Salehifard I	Dent Res J (Isfahan)	DRJ-19-36	2022
	Evaluation of Antimicrobial and Antibiofilm Activities of Copper Oxide Nanoparticles within Soft Denture Liners against Oral Pathogens.	Ansarifard E, Zareshahrabadi Z, Sarafraz N, Zomorodian K	Bioinorg Chem Appl	10.1155/2021/9939275	2021
	A New Approach Against Some Oral Pathogenic Bacteria Using a Chimeric Antimicrobial Peptide Derived from the Camel Milk; Lactoferrampin - Lactoferricin Chimer.	Mohammadipour HS, Akbari M, Tanhaeian A, Pourgonabadi S, Sekandari S, Karimian E	Curr Drug Discov Technol	10.2174/1570163817999201111193507	2021
	The effective and safe method for preventing and treating bacteria-induced dental diseases by herbal plants and a recombinant peptide.	Tanhaieian A, Pourgonabadi S, Akbari M, Mohammadipour HS	J Clin Exp Dent	10.4317/jced.55717	2020
	The functions of hydrophobic elastic polyurethane combined with an antibacterial triclosan derivative in the dentin restoration interface.	Guo X, Cheng Q, Yu G, Wang H, Tian Z, Shi Z, Cui Z, Zhu S	J Mech Behav Biomed Mater	10.1016/j.jmbbm.2019.103471	2019
Pathogenicity	A novel thymol-doped enamel bonding system: Physico-mechanical properties, bonding strength, and biological activity.	Rezaeian Z, Beigi-Boroujeni S, Atai M, Ebrahimibagha M, Ozcan M	J Mech Behav Biomed Mater	10.1016/j.jmbbm.2019.103378	2019
Enzymology	Zerumbone from Zingiber zerumbet (L.) smith: a potential prophylactic and therapeutic agent against the cariogenic bacterium Streptococcus mutans.	Moreira da Silva T, Pinheiro CD, Puccinelli Orlandi P, Pinheiro CC, Soares Pontes G	BMC Complement Altern Med	10.1186/s12906-018-2360-0	2018
Pathogenicity	Bactericidal dental nanocomposites containing 1,2,3-triazolium-functionalized POSS additive prepared through thiol-ene click polymerization.	Burujeny SB, Yeganeh H, Atai M, Gholami H, Sorayya M	Dent Mater	10.1016/j.dental.2016.11.001	2016
Pathogenicity	The efficacy of photodynamic and photothermal therapy on biofilm formation of Streptococcus mutans: An in vitro study.	Beytollahi L, Pourhajibagher M, Chiniforush N, Ghorbanzadeh R, Raoofian R, Pourakbari B, Bahador A	Photodiagnosis Photodyn Ther	10.1016/j.pdpdt.2016.10.006	2016
Pathogenicity	Effect of Lippia alba and Cymbopogon citratus essential oils on biofilms of Streptococcus mutans and cytotoxicity in CHO cells.	Tofino-Rivera A, Ortega-Cuadros M, Galvis-Pareja D, Jimenez-Rios H, Merini LJ, Martinez-Pabon MC	J Ethnopharmacol	10.1016/j.jep.2016.10.044	2016
	Comparison of Antibacterial Effects of ZnO and CuO Nanoparticles Coated Brackets against Streptococcus Mutans.	Ramazanzadeh B, Jahanbin A, Yaghoubi M, Shahtahmassbi N, Ghazvini K, Shakeri M, Shafaee H	J Dent (Shiraz)		2015
	Effects of biosurfactant produced by Lactobacillus casei on gtfB, gtfC, and ftf gene expression level in S. mutans by real-time RT-PCR.	Savabi O, Kazemi M, Kamali S, Salehi AR, Eslami G, Tahmourespour A, Salehi R	Adv Biomed Res	10.4103/2277-9175.145729	2014
	Effects of Lactobacillus reuteri-derived biosurfactant on the gene expression profile of essential adhesion genes (gtfB, gtfC and ftf) of Streptococcus mutans.	Salehi R, Savabi O, Kazemi M, Kamali S, Salehi AR, Eslami G, Tahmourespour A	Adv Biomed Res	10.4103/2277-9175.139134	2014
Phylogeny	The Comparison of Proteins Elaborated by Streptococcus mutans Strains Isolated from Caries Free and Susceptible Subjects.	Tahmourespour A, Nabinejad A, Shirian H, Ghasemipero N	Iran J Basic Med Sci		2013
Pathogenicity	Inhibition of attachment of oral bacteria to immortalized human gingival fibroblasts (HGF-1) by tea extracts and tea components.	Wang Y, Chung FF, Lee SM, Dykes GA	BMC Res Notes	10.1186/1756-0500-6-143	2013
Pathogenicity	Effect of water-aging on the antimicrobial activities of an ORMOSIL-containing orthodontic acrylic resin.	Gong SQ, Epasinghe DJ, Zhou B, Niu LN, Kimmerling KA, Rueggeberg FA, Yiu CK, Mao J, Pashley DH, Tay FR	Acta Biomater	10.1016/j.actbio.2013.02.031	2013
Enzymology	Evaluation of bacterial adhesion on machined titanium, Osseotite(R) and Nanotite(R) discs.	Rodriguez y Baena R, Arciola CR, Selan L, Battaglia R, Imbriani M, Rizzo S, Visai L	Int J Artif Organs	10.5301/ijao.5000143	2012
Metabolism	Glycan-binding specificities of Streptococcus mutans and Streptococcus sobrinus lectin-like adhesins.	Schuler V, Lussi A, Kage A, Seemann R	Clin Oral Investig	10.1007/s00784-011-0568-1	2011
	Evaluating the In-vitro Antibacterial Effect of Iranian Propolis on Oral Microorganisms.	Jafarzadeh Kashi TS, Kasra Kermanshahi R, Erfan M, Vahid Dastjerdi E, Rezaei Y, Tabatabaei FS	Iran J Pharm Res		2011
Pathogenicity	The effect of a probiotic strain (Lactobacillus acidophilus) on the plaque formation of oral Streptococci.	Tahmourespour A, Kermanshahi RK	Bosn J Basic Med Sci	10.17305/bjbms.2011.2621	2011
	Lactobacillus Acidophilus-Derived Biosurfactant Effect on GTFB and GTFC Expression Level in Streptococcus Mutans Biofilm Cells.	Tahmourespour A, Salehi R, Kasra Kermanshahi R	Braz J Microbiol	10.1590/S1517-83822011000100042	2011
Pathogenicity	Protective efficacy of Psidium cattleianum and Myracrodruon urundeuva aqueous extracts against caries development in rats.	Crivelaro de Menezes TE, Botazzo Delbem AC, Lourencao Brighenti F, Claudia Okamoto A, Gaetti-Jardim E Jr	Pharm Biol	10.3109/13880200903122202	2010
	Adhesion of Streptococcus mutans to different restorative materials.	Poggio C, Arciola CR, Rosti F, Scribante A, Saino E, Visai L	Int J Artif Organs	10.1177/039139880903200917	2009
Pathogenicity	Fluoride release and antibacterial activity of selected dental materials.	Marczuk-Kolada G, Jakoniuk P, Mystkowska J, Luczaj-Cepowicz E, Waszkiel D, Dabrowski JR, Leszczynska K	Postepy Hig Med Dosw (Online)	453293	2006
Pathogenicity	Modifications of hydrophobicity, in vitro adherence and cellular aggregation of Streptococcus mutans by Helichrysum italicum extract.	Nostro A, Cannatelli MA, Crisafi G, Musolino AD, Procopio F, Alonzo V	Lett Appl Microbiol	10.1111/j.1472-765X.2004.01509.x	2004
Pathogenicity	An evaluation of the action of different root canal irrigants on facultative aerobic-anaerobic, obligate anaerobic, and microaerophilic bacteria.	D'Arcangelo C, Varvara G, De Fazio P	J Endod	10.1016/S0099-2399(06)81170-2	1999
Pathogenicity	[Alpha-hemolytic streptococci and root canal irrigants. An evaluation of the bactericidal efficacy of sodium hypochlorite and chlorhexidine gluconate plus cetrimide].	D'Arcangelo C, Di Nardo Di Maio F, Varvara G	Minerva Stomatol		1998
Phylogeny	Inhibitory Effect of Bacillus licheniformis Strains Isolated from Canine Oral Cavity.	Surin Hudakova N, Kacirova J, Sondorova M, Selianova S, Mucha R, Madar M	Life (Basel)	10.3390/life12081238	2022

References

#2510	Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 6178
#20215	Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 )
#35120	; Curators of the CIP;
#52570	Culture Collection University of Gothenburg (CCUG) ; Curators of the CCUG; CCUG 35176
#68370	Automatically annotated from API 20STR .
#68381	Automatically annotated from API rID32STR .
#68382	Automatically annotated from API zym .
#121206	Collection of Institut Pasteur ; Curators of the CIP; CIP 103694
#124043	Isabel Schober, Julia Koblitz: Data extracted from sequence databases, automatically matched based on designation and taxonomy .
#125438	Julia Koblitz, Lorenz Christian Reimer, Rüdiger Pukall, Jörg Overmann: Predicting bacterial phenotypic traits through improved machine learning using high-quality, curated datasets. 2024 ( DOI 10.1101/2024.08.12.607695 )
#125439	Philipp Münch, René Mreches, Martin Binder, Hüseyin Anil Gündüz, Xiao-Yin To, Alice McHardy: deepG: Deep Learning for Genome Sequence Data. R package version 0.3.1 .
#126262	A. Lissin, I. Schober, J. F. Witte, H. Lüken, A. Podstawka, J. Koblitz, B. Bunk, P. Dawyndt, P. Vandamme, P. de Vos, J. Overmann, L. C. Reimer: StrainInfo—the central database for linked microbial strain identifiers. ( DOI 10.1093/database/baaf059 )

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Streptococcus mutans (DSM 6178, ATCC 35668, CCUG 35176)

Name and taxonomic classification

Morphology

Cell morphology

Colony morphology

Culture and growth conditions

Culture medium

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Physiology and metabolism

Oxygen tolerance

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Halophily

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API 20STR

API rID32STR

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