Strain identifier

BacDive ID: 8093

Type strain: Yes

Species: Acinetobacter baumannii

Strain Designation: 2208, 81

Strain history: CIP <- 1970, M. Piéchaud, Inst. Pasteur, Paris, France, Moraxella glucidolytica var. nonliquefaciens <- 1969, ATCC, Achromobacter anitratum <- R. Hugh: strain 2208 <- E.O. King <- I.G. Schaub: strain 81

NCBI tax ID(s): 575584 (strain), 470 (species)

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General

@ref: 9084

BacDive-ID: 8093

DSM-Number: 30007

keywords: genome sequence, 16S sequence, Bacteria, obligate aerobe, mesophilic, Gram-negative, antibiotic resistance

description: Acinetobacter baumannii 2208 is an obligate aerobe, mesophilic, Gram-negative bacterium that has multiple antibiotic resistances and was isolated from urine.

NCBI tax id

NCBI tax idMatching level
575584strain
470species

strain history

@refhistory
9084<- ATCC; ATCC 19606 <- R. Hugh; 2208 <- E. O. King; <- I. G. Schaub; 81 (Bacterium anitratum)
67770ATCC 19606 <-- R. Hugh 2208 <-- E. O. King <-- I. G. Schaub 81.
116742CIP <- 1970, M. Piéchaud, Inst. Pasteur, Paris, France, Moraxella glucidolytica var. nonliquefaciens <- 1969, ATCC, Achromobacter anitratum <- R. Hugh: strain 2208 <- E.O. King <- I.G. Schaub: strain 81

doi: 10.13145/bacdive8093.20230509.8.1

Name and taxonomic classification

LPSN

  • @ref: 20215
  • description: domain/bacteria
  • keyword: phylum/pseudomonadota
  • domain: Bacteria
  • phylum: Pseudomonadota
  • class: Gammaproteobacteria
  • order: Pseudomonadales
  • family: Moraxellaceae
  • genus: Acinetobacter
  • species: Acinetobacter baumannii
  • full scientific name: Acinetobacter baumannii Bouvet and Grimont 1986

@ref: 9084

domain: Bacteria

phylum: Proteobacteria

class: Gammaproteobacteria

order: Pseudomonadales

family: Moraxellaceae

genus: Acinetobacter

species: Acinetobacter baumannii

full scientific name: Acinetobacter baumannii Bouvet and Grimont 1986

strain designation: 2208, 81

type strain: yes

Morphology

cell morphology

@refgram stainconfidencecell shapemotility
69480negative99.996
116742negativeoval-shapedno

colony morphology

@reftype of hemolysisincubation period
9084gamma1-2 days
116742

Culture and growth conditions

culture medium

@refnamegrowthlinkcomposition
9084COLUMBIA BLOOD MEDIUM (DSMZ Medium 693)yeshttps://mediadive.dsmz.de/medium/693Name: COLUMBIA BLOOD MEDIUM (DSMZ Medium 693) Composition: Defibrinated sheep blood 50.0 g/l Columbia agar base
9084NUTRIENT AGAR (DSMZ Medium 1)yeshttps://mediadive.dsmz.de/medium/1Name: NUTRIENT AGAR (DSMZ Medium 1) Composition: Agar 15.0 g/l Peptone 5.0 g/l Meat extract 3.0 g/l Distilled water
42141MEDIUM 72- for trypto casein soja agaryesDistilled water make up to (1000.000 ml);Trypto casein soy agar (40.000 g)
9084TRYPTICASE SOY YEAST EXTRACT MEDIUM (DSMZ Medium 92)yeshttps://mediadive.dsmz.de/medium/92Name: TRYPTICASE SOY YEAST EXTRACT MEDIUM (DSMZ Medium 92) Composition: Trypticase soy broth 30.0 g/l Agar 15.0 g/l Yeast extract 3.0 g/l Distilled water
116742CIP Medium 72yeshttps://catalogue-crbip.pasteur.fr/fiche_milieu.xhtml?crbip=72

culture temp

@refgrowthtypetemperaturerange
9084positivegrowth30mesophilic
42141positivegrowth30mesophilic
9084positivegrowth37mesophilic
67770positivegrowth37mesophilic
116742positivegrowth22-44
116742nogrowth10psychrophilic

Physiology and metabolism

oxygen tolerance

  • @ref: 116742
  • oxygen tolerance: obligate aerobe

antibiogram

@refmediumincubation temperatureincubation timeoxygen conditionPenicillin Goxacillinampicillinticarcillinmezlocillincefalotincefazolincefotaximeaztreonamimipenemtetracyclinechloramphenicolgentamycinamikacinvancomycinerythromycinlincomycinofloxacinnorfloxacincolistinpipemidic acidnitrofurantoinbacitracinpolymyxin bkanamycinneomycindoxycyclineceftriaxoneclindamycinfosfomycinmoxifloxacinlinezolidnystatinquinupristin/dalfopristinteicoplaninpiperacillin/tazobactam
9084Mueller-Hinton Agar301aerob0002210-1200121032-34246-81420-22012026-281816060162418-203012-1401228000024
9084Mueller Hinton30aerob00024100010-128-1036240162201002616160601824203012-1408-1028000024

spore formation

@refspore formationconfidence
69481no100
69480no99.994

compound production

  • @ref: 9084
  • compound: siderophore acinetobactin

halophily

@refsaltgrowthtested relationconcentration
116742NaClpositivegrowth0-4 %
116742NaClnogrowth6 %
116742NaClnogrowth8 %
116742NaClnogrowth10 %

metabolite utilization

@refmetaboliteutilization activitykind of utilization testedChebi-ID
68371Potassium 5-ketogluconate-builds acid from
68371Potassium 2-ketogluconate-builds acid from
68371gluconate-builds acid from24265
68371L-arabitol-builds acid from18403
68371D-arabitol-builds acid from18333
68371L-fucose-builds acid from18287
68371D-fucose-builds acid from28847
68371D-tagatose-builds acid from16443
68371D-lyxose-builds acid from62318
68371turanose-builds acid from32528
68371gentiobiose-builds acid from28066
68371xylitol-builds acid from17151
68371glycogen-builds acid from28087
68371starch-builds acid from28017
68371raffinose-builds acid from16634
68371melezitose-builds acid from6731
68371inulin-builds acid from15443
68371trehalose-builds acid from27082
68371sucrose-builds acid from17992
68371melibiose-builds acid from28053
68371lactose-builds acid from17716
68371maltose-builds acid from17306
68371cellobiose-builds acid from17057
68371salicin-builds acid from17814
68371esculin-builds acid from4853
68371arbutin-builds acid from18305
68371amygdalin-builds acid from27613
68371N-acetylglucosamine-builds acid from59640
68371methyl alpha-D-glucopyranoside-builds acid from320061
68371methyl alpha-D-mannoside-builds acid from43943
68371D-sorbitol-builds acid from17924
68371D-mannitol-builds acid from16899
68371myo-inositol-builds acid from17268
68371galactitol-builds acid from16813
68371L-rhamnose-builds acid from62345
68371L-sorbose-builds acid from17266
68371D-mannose-builds acid from16024
68371D-fructose-builds acid from15824
68371D-glucose-builds acid from17634
68371D-galactose-builds acid from12936
68371methyl beta-D-xylopyranoside-builds acid from74863
68371ribitol-builds acid from15963
68371L-xylose-builds acid from65328
68371D-xylose-builds acid from65327
68371D-ribose-builds acid from16988
68371L-arabinose-builds acid from30849
68371D-arabinose-builds acid from17108
68371erythritol-builds acid from17113
68371glycerol-builds acid from17754
68369malate+assimilation25115
68369adipate+assimilation17128
68369decanoate+assimilation27689
68369gluconate-assimilation24265
68369maltose-assimilation17306
68369N-acetylglucosamine-assimilation59640
68369D-mannitol-assimilation16899
68369D-mannose-assimilation16024
68369L-arabinose+assimilation30849
68369esculin-hydrolysis4853
68369urea-hydrolysis16199
68369arginine-hydrolysis29016
68369tryptophan-energy source27897
68369nitrate-reduction17632
116742nitrate-reduction17632
116742nitrite-reduction16301
116742glucose+/-degradation17234
116742nitrate-respiration17632

antibiotic resistance

  • @ref: 116742
  • metabolite: 0129 (2,4-Diamino-6,7-di-iso-propylpteridine phosphate)
  • is antibiotic: yes
  • is sensitive: no
  • is resistant: yes

metabolite production

@refChebi-IDmetaboliteproduction
6836935581indoleno
11674235581indoleno

metabolite tests

@refChebi-IDmetaboliteindole testvoges-proskauer-testmethylred-test
6836935581indole-
11674215688acetoin-
11674217234glucose+

enzymes

@refvalueactivityec
9084catalase+1.11.1.6
68369cytochrome oxidase-1.9.3.1
68369beta-glucosidase-3.2.1.21
68369urease-3.5.1.5
68369arginine dihydrolase-3.5.3.6
116742oxidase-
116742beta-galactosidase-3.2.1.23
116742gelatinase-
116742catalase+1.11.1.6
116742gamma-glutamyltransferase+2.3.2.2
116742urease-3.5.1.5
68382alkaline phosphatase+3.1.3.1
68382esterase (C 4)+
68382esterase lipase (C 8)+
68382lipase (C 14)-
68382leucine arylamidase+3.4.11.1
68382valine arylamidase-
68382cystine arylamidase-3.4.11.3
68382trypsin-3.4.21.4
68382alpha-chymotrypsin-3.4.21.1
68382acid phosphatase+3.1.3.2
68382naphthol-AS-BI-phosphohydrolase+
68382alpha-galactosidase-3.2.1.22
68382beta-galactosidase-3.2.1.23
68382beta-glucuronidase-3.2.1.31
68382alpha-glucosidase-3.2.1.20
68382beta-glucosidase-3.2.1.21
68382N-acetyl-beta-glucosaminidase-3.2.1.52
68382alpha-mannosidase-3.2.1.24
68382alpha-fucosidase-3.2.1.51

API zym

@refControlAlkaline phosphataseEsteraseEsterase LipaseLipaseLeucine arylamidaseValine arylamidaseCystine arylamidaseTrypsinalpha- ChymotrypsinAcid phosphataseNaphthol-AS-BI-phosphohydrolasealpha- Galactosidasebeta- Galactosidasebeta- Glucuronidasealpha- Glucosidasebeta- GlucosidaseN-acetyl-beta- glucosaminidasealpha- Mannosidasealpha- Fucosidase
116742-+++-+----++--------

API 20NE

@refNO3TRPGLU_ FermADH ArgUREESCGELPNPGGLU_ AssimARAMNEMANNAGMALGNTCAPADIMLTCITPACOX
9084--+-----+/-+-----+++++-
9084--+------+-----+++++-
9084------+--+-----+++++-
9084--------++-----+++++-
9084--+------+-----+++++-
9084--+------+-----+++++
9084--+-----+/-+-----+++++
9084--+-----+/-+-----+++++-

API 50CHac

@refGLYERYDARALARARIBDXYLLXYLADOMDXGALGLUFRUMNESBERHADULINOMANSORMDMMDGNAGAMYARBESCSALCELMALLACMELSACTREINUMLZRAFAMDGLYGXLTGENTURLYXTAGDFUCLFUCDARLLARLGNT2KG5KG
116742-------------------------------------------------

API biotype100

@refGLUFRUGALTREMNESBEMELSACRAFMTEMALLACLTEMbGaMaGaCELGENMbGuESCRIBARAXYLPLERHAFUCMLZDARLLARLXLTDULTAGGLYINOMANMTLTURSORADOHBGLYXERYMDG3MDGSATMUCLTATDTATMTATDMLTLMLTCATETATETTECITGRTGAT2KG5KGTRYNAGGNTPACPATpOBEQATGTEmOBEBATPPATCMTTGEBETPCEABTHINLATCAPCYTHISSUCFUMGREGYTAVTETNTTNGLNITA3OBUAPTGTTPRODALALALASERMNTPROPTYR2KT
116742+------------------+++---------------------++---++++++----+--++++--+--+-++-+++++++------++++++-+++-

Isolation, sampling and environmental information

isolation

@refsample type
9084urine
67770Urine
116742Urine

isolation source categories

  • Cat1: #Host Body Product
  • Cat2: #Fluids
  • Cat3: #Urine

taxonmaps

  • @ref: 69479
  • File name: preview.99_14.png
  • url: https://microbeatlas.org/index.html?action=taxon&taxon_id=90_8;96_11;97_11;98_13;99_14&stattab=map
  • Last taxonomy: Acinetobacter baumannii
  • 16S sequence: Z93435
  • Sequence Identity:
  • Total samples: 10225
  • soil counts: 605
  • aquatic counts: 4013
  • animal counts: 5073
  • plant counts: 534

Safety information

risk assessment

@refbiosafety levelbiosafety level comment
90842Risk group (German classification)
1167421Risk group (French classification)

Sequence information

16S sequences

@refdescriptionaccessionlengthdatabaseNCBI tax ID
20218Acinetobacter baumannii 16S rRNA gene, partialAJ247197452ena470
20218Acinetobacter baumannii strain CIP 70.34 16S ribosomal RNA gene, partial sequenceFJ8673541528ena470
20218Acinetobacter baumannii genomic DNA containing 16S-23S IGS, strain ATCC 19606, clone 01HE651629608ena470
20218Acinetobacter baumannii genomic DNA containing 16S-23S IGS, strain ATCC 19606, clone 03HE651630608ena470
20218Acinetobacter baumannii genomic DNA containing 16S-23S IGS, strain ATCC 19606, clone 04HE651631608ena470
20218Acinetobacter baumannii genomic DNA containing 16S-23S IGS, strain ATCC 19606, clone 05HE651632608ena470
20218Acinetobacter baumannii genomic DNA containing 16S-23S IGS, strain ATCC 19606, clone 06HE651633608ena470
20218Acinetobacter baumannii genomic DNA containing 16S-23S IGS, strain ATCC 19606, clone 09HE651634608ena470
20218Acinetobacter baumannii genomic DNA containing 16S-23S IGS, strain ATCC 19606, clone 10HE651635608ena470
20218Acinetobacter baumannii genomic DNA containing 16S-23S IGS, strain ATCC 19606, clone 11HE651636608ena470
20218Acinetobacter baumannii genomic DNA containing 16S-23S IGS, strain ATCC 19606, clone 13HE651637608ena470
20218Acinetobacter baumannii genomic DNA containing 16S-23S IGS, strain ATCC 19606, clone 18HE651638608ena470
20218Acinetobacter baumannii genomic DNA containing 16S-23S IGS, strain ATCC 19606, clone 22HE651639608ena470
20218Acinetobacter baumannii 16S rRNA gene, strain ATCC 19606HE6519071529ena470
20218Acinetobacter baumannii 16S-23S ribosomal RNA intergenic spacer, including Ile-tRNA and Ala-tRNA genesU60279621ena470
20218Acinetobacter baumanni 16S rRNA gene (strain ATCC 19606T)Z934351416ena470
9084A.baumannii 16S rRNA gene (DSM30007)X816601459ena470
9084Acinetobacter baumannii partial 16S rRNA gene, type strain DSM 30007THE9782671515ena470
67770Acinetobacter baumannii gene for 16S rRNA, partial sequence, strain: JCM 6841AB5947651459ena470

Genome sequences

@refdescriptionaccessionassembly leveldatabaseNCBI tax ID
66792Acinetobacter baumannii ATCC 19606GCA_009035845completencbi470
66792Acinetobacter baumannii ATCC 19606GCA_014672755completencbi470
66792Acinetobacter baumannii ATCC 19606GCA_009759685completencbi470
66792Acinetobacter baumannii ATCC 19606 = CIP 70.34 = JCM 6841GCA_019331655completencbi575584
66792Acinetobacter baumannii NCTC12156GCA_900444725contigncbi470
66792Acinetobacter baumannii ATCC 19606GCA_014116795scaffoldncbi470
66792Acinetobacter baumannii DSM 30007GCA_017090145contigncbi470
66792Acinetobacter baumannii ATCC19606GCA_900011295contigncbi470
66792Acinetobacter baumannii ATCC 19606 = CIP 70.34 = JCM 6841GCA_002811175scaffoldncbi575584
66792Acinetobacter baumannii ATCC 19606 = CIP 70.34 = JCM 6841GCA_000737145scaffoldncbi575584
66792Acinetobacter baumannii ATCC 19606 = CIP 70.34 = JCM 6841GCA_000369385scaffoldncbi575584
66792Acinetobacter baumannii NBRC 109757GCA_000931755contigncbi470
66792Acinetobacter baumannii 81GCA_016746035contigncbi470
66792Acinetobacter baumannii ATCC 19606 = CIP 70.34 = JCM 6841GCA_000614705contigncbi575584
66792Acinetobacter baumannii ATCC 19606 = CIP 70.34575584.18wgspatric575584
66792Acinetobacter baumannii ATCC 19606 = CIP 70.34575584.3wgspatric575584
66792Acinetobacter baumannii ATCC 19606 = CIP 70.34575584.19wgspatric575584
66792Acinetobacter baumannii ATCC 19606 = CIP 70.34 = JCM 6841575584.33wgspatric575584
66792Acinetobacter baumannii ATCC 19606 = CIP 70.34 = JCM 6841575584.58completepatric575584
66792Acinetobacter baumannii JCM 68411236532.3wgspatric575584
66792Acinetobacter baumannii strain ATCC 19606470.10973wgspatric470
66792Acinetobacter baumannii strain ATCC 19606470.11567completepatric470
66792Acinetobacter baumannii strain ATCC 19606470.11740wgspatric470
66792Acinetobacter baumannii strain ATCC 19606470.9626completepatric470
66792Acinetobacter baumannii strain ATCC 19606470.12191completepatric470
66792Acinetobacter baumannii strain ATCC 19606_3M470.11738wgspatric470
66792Acinetobacter baumannii strain ATCC 19606_5M470.11739wgspatric470
66792Acinetobacter baumannii strain ATCC19606470.2129wgspatric470
66792Acinetobacter baumannii strain DSM 30007470.13019wgspatric470
66792Acinetobacter baumannii strain NBRC 109757470.1319wgspatric470
66792Acinetobacter baumannii strain NCTC12156470.5453wgspatric470
66792Acinetobacter baumannii ATCC 19606647533101draftimg575584
66792Acinetobacter baumannii ATCC 196062609460113draftimg575584
66792Acinetobacter baumannii NBRC 1097572700989282draftimg470
66792Acinetobacter baumannii ATCC 196062916668946draftimg575584
66792Acinetobacter baumannii CIP 70.342534682196draftimg575584
66792Acinetobacter baumannii JCM 68412585427930draftimg575584
67770Acinetobacter baumannii ATCC 19606 = CIP 70.34 = JCM 6841GCA_000162295scaffoldncbi575584
66792Acinetobacter baumannii ATCC 19606GCA_020911985completencbi470
66792Acinetobacter baumannii ATCC19606-VUBGCA_022466975completencbi470
66792Acinetobacter baumannii ATCC 19606GCA_025919905contigncbi470
66792Acinetobacter baumannii strain ATCC 19606470.15027completepatric470
66792Acinetobacter baumannii 81GCA_018123985contigncbi470

Genome-based predictions

predictions

traitpredictionconfidencetraining_data
spore-formingno100no
flagellatedno92.922no
gram-positiveno96.962no
anaerobicno98.373no
aerobicyes93.997no
halophileno90.999no
spore-formingno96.319no
motileno91.55no
thermophileno99.868no
glucose-utilno62.007no
glucose-fermentno82.112no

External links

@ref: 9084

culture collection no.: DSM 30007, ATCC 19606, CIP 70.34, DSM 6974, JCM 6841, CCUG 19096, CGMCC 1.6769, IAM 12088, KCTC 2508, LMG 1041, LMG 10545, NBRC 109757, NCIMB 12457, NCTC 12156

straininfo link

  • @ref: 77520
  • straininfo: 92085

literature

topicPubmed-IDtitleauthorsjournalDOIyearmeshtopic2
Phylogeny7802543Isolation and structure elucidation of acinetobactin, a novel siderophore from Acinetobacter baumannii.Yamamoto S, Okujo N, Sakakibara YArch Microbiol10.1007/BF003018461994Acinetobacter/*chemistry, Imidazoles/*chemistry/isolation & purification, Magnetic Resonance Spectroscopy, Oxazoles/*chemistry/isolation & purification, Siderophores/*chemistry/isolation & purification, Species Specificity, Spectrometry, Mass, Fast Atom BombardmentEnzymology
Enzymology7813892Cloning and expression in Escherichia coli of the gene encoding a novel L-2,4-diaminobutyrate decarboxylase of Acinetobacter baumannii.Ikai H, Yamamoto SFEMS Microbiol Lett10.1016/0378-1097(94)90253-41994Acinetobacter/*enzymology/genetics, Blotting, Southern, Carboxy-Lyases/*genetics, Cloning, Molecular, DNA Probes, DNA, Bacterial/genetics, Escherichia coli/*genetics
Enzymology8219496Immunobiology of Acinetobacter baumannii and genospecies 3.Traub WH, Bauer DZentralbl Bakteriol10.1016/s0934-8840(11)80403-21993Acinetobacter/classification/*immunology, Acinetobacter Infections/immunology/microbiology, Animals, Antibodies, Bacterial/*biosynthesis, Bacteremia/immunology/microbiology, Blotting, Western, Electrophoresis, Polyacrylamide Gel, Enzyme-Linked Immunosorbent Assay, Humans, Rabbits, SerotypingPathogenicity
Enzymology9660198Cloning and characterization of 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) transferase genes (kdtA) from Acinetobacter baumannii and Acinetobacter haemolyticus.Bode CE, Brabetz W, Brade HEur J Biochem10.1046/j.1432-1327.1998.2540404.x1998Acinetobacter/*enzymology/*genetics, Amino Acid Sequence, Base Sequence, Cloning, Molecular, Corynebacterium/genetics, DNA Primers/genetics, Escherichia coli/genetics, *Genes, Bacterial, Genetic Vectors, Molecular Sequence Data, Phylogeny, Plasmids/genetics, Recombinant Proteins/genetics/metabolism, Sequence Homology, Amino Acid, Transferases/*genetics/metabolismGenetics
Pathogenicity10824036Bactericidal and bacteriostatic activity of gemifloxacin against Acinetobacter spp. in vitro.Higgins PG, Coleman K, Amyes SGJ Antimicrob Chemother10.1093/jac/45.suppl_3.712000Acinetobacter/*drug effects, Anti-Infective Agents/*pharmacology, Dose-Response Relationship, Drug, *Fluoroquinolones, Gemifloxacin, Microbial Sensitivity Tests, Naphthyridines/*pharmacology, Time Factors
Metabolism11532195Monoclonal antibodies against the iron regulated outer membrane Proteins of Acinetobacter baumannii are bactericidal.Goel VK, Kapil ABMC Microbiol10.1186/1471-2180-1-162001Acinetobacter/*drug effects/immunology/metabolism, Antibodies, Bacterial/*pharmacology, Antibodies, Monoclonal/*pharmacology, Bacterial Outer Membrane Proteins, Bacterial Proteins/biosynthesis/*immunology, Biological Transport, Iron/*metabolism, Iron Radioisotopes, Iron-Binding Proteins, Microbial Sensitivity Tests, Periplasmic Binding Proteins, Siderophores/metabolismPathogenicity
Genetics11856300The structure of the carbohydrate backbone of the lipopolysaccharide from Acinetobacter baumannii strain ATCC 19606.Vinogradov EV, Duus JO, Brade H, Holst OEur J Biochem10.1046/j.0014-2956.2001.02647.x2002Acinetobacter/*chemistry, Carbohydrate Conformation, Carbohydrate Sequence, Chromatography, Gel, Mass Spectrometry, Models, Molecular, Molecular Sequence Data, Nuclear Magnetic Resonance, Biomolecular, O Antigens/*chemistry/isolation & purificationEnzymology
Metabolism15289555Identification and transcriptional organization of a gene cluster involved in biosynthesis and transport of acinetobactin, a siderophore produced by Acinetobacter baumannii ATCC 19606T.Mihara K, Tanabe T, Yamakawa Y, Funahashi T, Nakao H, Narimatsu S, Yamamoto SMicrobiology (Reading)10.1099/mic.0.27141-02004Acinetobacter baumannii/*genetics/*metabolism, Bacterial Proteins/genetics/metabolism, Base Sequence, Biological Transport, Active, Cloning, Molecular, Cytosol/metabolism, DNA, Bacterial/genetics, *Genes, Bacterial, Imidazoles/*metabolism, Iron/metabolism, Models, Biological, Molecular Sequence Data, *Multigene Family, Mutation, Oxazoles/*metabolism, Phenotype, Restriction Mapping, Siderophores/*biosynthesis/*genetics, Transcription, GeneticEnzymology
Metabolism15528653The siderophore-mediated iron acquisition systems of Acinetobacter baumannii ATCC 19606 and Vibrio anguillarum 775 are structurally and functionally related.Dorsey CW, Tomaras AP, Connerly PL, Tolmasky ME, Crosa JH, Actis LAMicrobiology (Reading)10.1099/mic.0.27371-02004Acinetobacter baumannii/*genetics/metabolism, Adenosine Triphosphatases/genetics, Bacterial Outer Membrane Proteins/genetics/immunology, Bacterial Proteins/genetics/metabolism, DNA, Bacterial/chemistry/isolation & purification, Gene Order, Genes, Bacterial, Imidazoles/chemistry/metabolism, Immunoblotting, Iron/*metabolism, Membrane Proteins/genetics, Molecular Sequence Data, Mutagenesis, Insertional, Mutation, Operon, Oxazoles/chemistry/metabolism, Peptides/chemistry/metabolism, Sequence Analysis, DNA, Siderophores/chemistry/*genetics/metabolism, Vibrio/*genetics/metabolism, VibrionaceaeGenetics
Phylogeny16123830Genomic species identification of Acinetobacter of clinical isolates by 16S rDNA sequencing.Misbah S, Hassan H, Yusof MY, Hanifah YA, AbuBakar SSingapore Med J2005Acinetobacter baumannii/*genetics/isolation & purification, Base Sequence, DNA, Bacterial/*genetics, DNA, Ribosomal/*genetics, Databases, Genetic, Genes, Bacterial/*genetics, Genome, Humans, RNA, Ribosomal, 16S/*geneticsGenetics
Pathogenicity16940086Heteroresistance to colistin in multidrug-resistant Acinetobacter baumannii.Li J, Rayner CR, Nation RL, Owen RJ, Spelman D, Tan KE, Liolios LAntimicrob Agents Chemother10.1128/AAC.00103-062006Acinetobacter Infections/microbiology, Acinetobacter baumannii/*drug effects/isolation & purification, Anti-Bacterial Agents/*pharmacology, Colistin/*pharmacology, *Drug Resistance, Multiple, Bacterial, Electrophoresis, Gel, Pulsed-Field/methods, Humans, Microbial Sensitivity TestsEnzymology
Pathogenicity17289768In vitro pharmacodynamics of colistin against Acinetobacter baumannii clinical isolates.Owen RJ, Li J, Nation RL, Spelman DJ Antimicrob Chemother10.1093/jac/dkl5122007Acinetobacter baumannii/*drug effects, Anti-Bacterial Agents/*pharmacology, Colistin/*pharmacology, Dose-Response Relationship, Drug, Drug Resistance, Bacterial, Humans, Microbial Sensitivity Tests
Enzymology18558944Molecular epidemiology of clinical Acinetobacter baumannii and Acinetobacter genomic species 13TU isolates using a multilocus sequencing typing scheme.Wisplinghoff H, Hippler C, Bartual SG, Haefs C, Stefanik D, Higgins PG, Seifert HClin Microbiol Infect10.1111/j.1469-0691.2008.02010.x2008Acinetobacter Infections/*epidemiology/microbiology, Acinetobacter baumannii/*classification/*genetics, *Bacterial Typing Techniques, DNA, Bacterial/isolation & purification, *Disease Outbreaks, Electrophoresis, Gel, Pulsed-Field, Europe/epidemiology, Humans, Molecular Epidemiology, Random Amplified Polymorphic DNA Technique, Sequence Analysis, DNA, United States/epidemiologyPhylogeny
Pathogenicity19253303The cost of resistance to colistin in Acinetobacter baumannii: a proteomic perspective.Fernandez-Reyes M, Rodriguez-Falcon M, Chiva C, Pachon J, Andreu D, Rivas LProteomics10.1002/pmic.2008004342009Acinetobacter baumannii/*drug effects, Bacterial Proteins/metabolism, Colistin/*pharmacology, Drug Resistance, Bacterial/*drug effects, Electrophoresis, Gel, Two-Dimensional, Gene Expression Profiling, Phenotype, Proteomics/*methodsEnzymology
19318826Therapeutic efficacy of buforin II and rifampin in a rat model of Acinetobacter baumannii sepsis.Cirioni O, Silvestri C, Ghiselli R, Orlando F, Riva A, Gabrielli E, Mocchegiani F, Cianforlini N, Trombettoni MM, Saba V, Scalise G, Giacometti ACrit Care Med10.1097/CCM.0b013e31819c3e222009Acinetobacter Infections/*drug therapy, *Acinetobacter baumannii, Animals, Antibiotics, Antitubercular/*therapeutic use, Disease Models, Animal, Male, Proteins/*therapeutic use, Rats, Rats, Wistar, Rifampin/*therapeutic use, Sepsis/*drug therapy/*microbiology
Pathogenicity19530313CsuA/BABCDE-dependent pili are not involved in the adherence of Acinetobacter baumannii ATCC19606(T) to human airway epithelial cells and their inflammatory response.de Breij A, Gaddy J, van der Meer J, Koning R, Koster A, van den Broek P, Actis L, Nibbering P, Dijkshoorn LRes Microbiol10.1016/j.resmic.2009.01.0022009Acinetobacter baumannii/genetics/*physiology/ultrastructure, Animals, *Bacterial Adhesion, Epithelial Cells/*immunology/*microbiology, Erythrocytes/microbiology, Fimbriae, Bacterial/genetics/*physiology/ultrastructure, Gene Deletion, Genes, Bacterial, Humans, Inflammation/*microbiology, Interleukin-6/metabolism, Interleukin-8/metabolism, Microscopy, Electron, Scanning, Respiratory Mucosa/immunology/microbiology, SheepMetabolism
Pathogenicity19616347Synthesis, characterization and evaluation of antibacterial activity of some thiazolo[3,2-b][1,2,4]triazole incorporating diphenylsulfone moieties.Barbuceanu SF, Almajan GL, Saramet I, Draghici C, Tarcomnicu AI, Bancescu GEur J Med Chem10.1016/j.ejmech.2009.06.0212009Anti-Bacterial Agents/*chemistry/*pharmacology, Bacteria/drug effects, Biphenyl Compounds/chemistry/pharmacology, Microbial Sensitivity Tests, Molecular Structure, Structure-Activity Relationship, Sulfones/*chemistry/*pharmacology, Triazoles/*chemistry/*pharmacology
Metabolism19770279OXA-143, a novel carbapenem-hydrolyzing class D beta-lactamase in Acinetobacter baumannii.Higgins PG, Poirel L, Lehmann M, Nordmann P, Seifert HAntimicrob Agents Chemother10.1128/AAC.00856-092009Acinetobacter baumannii/drug effects/*enzymology/genetics, Amino Acid Sequence, Anti-Bacterial Agents/metabolism/pharmacology, Carbapenems/*metabolism/pharmacology, Drug Resistance, Multiple, Bacterial/genetics/physiology, Escherichia coli/genetics/metabolism, Imipenem/metabolism/pharmacology, Meropenem, Molecular Sequence Data, Oxacillin/metabolism/pharmacology, Penicillins/metabolism/pharmacology, Polymerase Chain Reaction, Sequence Analysis, DNA, Sequence Homology, Amino Acid, Thienamycins/metabolism/pharmacology, beta-Lactamases/chemistry/genetics/*physiologyGenetics
Genetics20041708Quantitative profiling and identification of outer membrane proteins of beta-lactam resistant strain of Acinetobacter baumannii.Vashist J, Tiwari V, Kapil A, Rajeswari MRJ Proteome Res10.1021/pr90111882010Acinetobacter baumannii/*drug effects, Amino Acid Sequence, Bacterial Outer Membrane Proteins/chemistry/*metabolism, Drug Resistance, Microbial, Microbial Sensitivity Tests, Molecular Sequence Data, Spectrometry, Mass, Electrospray Ionization, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization, beta-Lactams/*pharmacologyPathogenicity
Enzymology20573659fAUC/MIC is the most predictive pharmacokinetic/pharmacodynamic index of colistin against Acinetobacter baumannii in murine thigh and lung infection models.Dudhani RV, Turnidge JD, Nation RL, Li JJ Antimicrob Chemother10.1093/jac/dkq2262010Acinetobacter Infections/*drug therapy/pathology, Acinetobacter baumannii/drug effects/*pathogenicity, Animals, Anti-Bacterial Agents/pharmacokinetics/pharmacology/*therapeutic use, Area Under Curve, Colistin/pharmacokinetics/pharmacology/*therapeutic use, Colony Count, Microbial, Disease Models, Animal, Drug Resistance, Multiple, Bacterial, Female, Lung/microbiology/*pathology, Mice, Microbial Sensitivity Tests, Thigh/microbiology/*pathologyPathogenicity
Metabolism20576751DnaK and GroEL are induced in response to antibiotic and heat shock in Acinetobacter baumannii.Cardoso K, Gandra RF, Wisniewski ES, Osaku CA, Kadowaki MK, Felipach-Neto V, Haus LFA, Simao RCGJ Med Microbiol10.1099/jmm.0.020339-02010Acinetobacter baumannii/drug effects/*metabolism, Adenosine Triphosphatases/genetics/*metabolism, Anti-Bacterial Agents/*pharmacology, Chaperonin 60/genetics/*metabolism, Drug Resistance, Multiple, Bacterial/physiology, *Gene Expression Regulation, Bacterial, *Hot TemperatureStress
Pathogenicity20666717In vitro synergistic antibacterial action of certain combinations of gentamicin and essential oils.Rosato A, Piarulli M, Corbo F, Muraglia M, Carone A, Vitali ME, Vitali CCurr Med Chem10.2174/0929867107922319962010Anti-Bacterial Agents/*pharmacology, Drug Combinations, Drug Synergism, Gentamicins/*pharmacology, Gram-Negative Bacteria/drug effects, Gram-Positive Bacteria/drug effects, Microbial Sensitivity Tests, Oils, Volatile/*pharmacology
Metabolism20692388Deciphering the iron response in Acinetobacter baumannii: A proteomics approach.Nwugo CC, Gaddy JA, Zimbler DL, Actis LAJ Proteomics10.1016/j.jprot.2010.07.0102010Acinetobacter baumannii/*drug effects/genetics/growth & development/metabolism, Bacterial Outer Membrane Proteins/genetics/metabolism, Cells, Cultured, Electrophoresis, Gel, Two-Dimensional, Iron/chemistry/*pharmacology, Iron Chelating Agents/chemistry/*pharmacology, Mass Spectrometry, Proteomics/*methods, RNA, Small Interfering/genetics/metabolismEnzymology
Metabolism20855724Colistin resistance in Acinetobacter baumannii is mediated by complete loss of lipopolysaccharide production.Moffatt JH, Harper M, Harrison P, Hale JD, Vinogradov E, Seemann T, Henry R, Crane B, St Michael F, Cox AD, Adler B, Nation RL, Li J, Boyce JDAntimicrob Agents Chemother10.1128/AAC.00834-102010Acinetobacter baumannii/*drug effects/*metabolism, Acyltransferases/genetics, Amidohydrolases/genetics, Anti-Bacterial Agents/*pharmacology, Bacterial Proteins/genetics, Colistin/*pharmacology, Drug Resistance, Multiple, Bacterial/genetics, Genetic Complementation Test, Lipopolysaccharides/*metabolism, Microscopy, Electron, Transmission, MutationBiotechnology
Pathogenicity21081544Different surface charge of colistin-susceptible and -resistant Acinetobacter baumannii cells measured with zeta potential as a function of growth phase and colistin treatment.Soon RL, Nation RL, Cockram S, Moffatt JH, Harper M, Adler B, Boyce JD, Larson I, Li JJ Antimicrob Chemother10.1093/jac/dkq4222010Acinetobacter Infections/drug therapy/*microbiology, Acinetobacter baumannii/*drug effects/isolation & purification, Anti-Bacterial Agents/*pharmacology, Colistin/*pharmacology, *Drug Resistance, Multiple, Bacterial, *Electricity, Genes, Bacterial, Humans, Lipopolysaccharides/biosynthesis/chemistry, Microbial Sensitivity Tests, Mutation, Static ElectricityEnzymology
Enzymology21146712Demonstration of an outer membrane protein that is antigenically specific for Acinetobacter baumannii.Islam AH, Singh KK, Ismail ADiagn Microbiol Infect Dis10.1016/j.diagmicrobio.2010.09.0082011Acinetobacter Infections/*diagnosis/microbiology, Acinetobacter baumannii/chemistry/*immunology/*isolation & purification, Antibodies, Bacterial/*blood, Antigens, Bacterial/*immunology/isolation & purification, Bacterial Outer Membrane Proteins/*immunology/isolation & purification, Bacteriological Techniques/*methods, Humans, Immunoassay/methods, Immunoglobulin A/blood, Immunoglobulin G/blood, Immunoglobulin M/blood, Sensitivity and SpecificityPhylogeny
Pathogenicity21288481Acinetobacter baumannii-induced lung cell death: role of inflammation, oxidative stress and cytosolic calcium.Smani Y, Docobo-Perez F, McConnell MJ, Pachon JMicrob Pathog10.1016/j.micpath.2011.01.0082011Acinetobacter baumannii/*pathogenicity, Calcium/*metabolism, Calpain/metabolism, Caspase 3/metabolism, *Cell Death, Epithelial Cells/*microbiology, Humans, Inflammation/*pathology, Lung/microbiology/pathology, *Oxidative Stress, Time FactorsMetabolism
Metabolism21386968Acinetobacter baumannii secretes cytotoxic outer membrane protein A via outer membrane vesicles.Jin JS, Kwon SO, Moon DC, Gurung M, Lee JH, Kim SI, Lee JCPLoS One10.1371/journal.pone.00170272011Acinetobacter Infections/metabolism/microbiology/pathology, Acinetobacter baumannii/*metabolism/pathogenicity/physiology/ultrastructure, Bacterial Outer Membrane Proteins/chemistry/metabolism, Cell Wall/metabolism/*physiology, Cells, Cultured, HeLa Cells, Host-Pathogen Interactions/physiology, Humans, Protein Structure, Tertiary/physiology, Secretory Vesicles/*metabolism, Staphylococcal Protein A/chemistry/*metabolism, U937 Cells, Virulence Factors/chemistry/metabolismPathogenicity
Metabolism21441690Analysis of penicillin-binding proteins (PBPs) in carbapenem resistant Acinetobacter baumannii.Vashist J, Tiwari V, Das R, Kapil A, Rajeswari MRIndian J Med ResIndianJMedRes_2011_133_3_332_783802011Acinetobacter baumannii/drug effects/*metabolism, Amino Acid Sequence, Anti-Bacterial Agents/*pharmacology, Carbapenems/*pharmacology, Drug Resistance, Microbial, Electrophoresis, Polyacrylamide Gel, Microbial Sensitivity Tests, Molecular Sequence Data, Penicillin-Binding Proteins/chemistry/*metabolism, Spectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationEnzymology
Metabolism21538245Acinetobacter baumannii biofilms: variations among strains and correlations with other cell properties.McQueary CN, Actis LAJ Microbiol10.1007/s12275-011-0343-72011Acinetobacter baumannii/chemistry/growth & development/metabolism/*physiology, Biofilms/*growth & development, DNA, Bacterial/genetics, Fimbriae, Bacterial/genetics/metabolism, Genes, Bacterial, *Genetic Variation, Genotype, Humans, Hydrophobic and Hydrophilic Interactions, Locomotion, Molecular Chaperones/genetics, Phenotype, Polymerase Chain ReactionGenetics
Metabolism21576434Phosphoethanolamine modification of lipid A in colistin-resistant variants of Acinetobacter baumannii mediated by the pmrAB two-component regulatory system.Beceiro A, Llobet E, Aranda J, Bengoechea JA, Doumith M, Hornsey M, Dhanji H, Chart H, Bou G, Livermore DM, Woodford NAntimicrob Agents Chemother10.1128/AAC.00079-112011Acinetobacter baumannii/*drug effects/genetics/*metabolism, Anti-Bacterial Agents/*pharmacology, Bacterial Proteins/genetics/*metabolism, Colistin/*pharmacology, Drug Resistance, Bacterial/genetics, Ethanolamines/*metabolism, Lipid A/*metabolism, Molecular Sequence Data, Reverse Transcriptase Polymerase Chain Reaction, Spectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationGenetics
Pathogenicity21651845[Expressions of pgaABC gene clusters and changes in biofilm phenotype of Acinetobacter baumannii in burn patients].Xiang J, Sun Z, Song F, Huan JNZhonghua Shao Shang Za Zhi2011Acinetobacter Infections/*microbiology, Acinetobacter baumannii/*genetics/isolation & purification, *Biofilms, Burns/*microbiology, Genes, Bacterial, Humans, *Multigene FamilyPhenotype
21679737Outer membrane vesicles as an acellular vaccine against Acinetobacter baumannii.McConnell MJ, Rumbo C, Bou G, Pachon JVaccine10.1016/j.vaccine.2011.06.0012011Acinetobacter Infections/immunology/*prevention & control, Acinetobacter baumannii/*immunology, Animals, Antigens, Bacterial/immunology, Bacterial Load/immunology, Bacterial Outer Membrane Proteins/*immunology, Bacterial Vaccines/*immunology, Enzyme-Linked Immunosorbent Assay, Immunoglobulin G, Immunoglobulin M, Interleukin-1beta/blood, Interleukin-6/blood, Mice, Mice, Inbred C57BL, Microscopy, Electron, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
Pathogenicity21996406Imipenem: a potent inducer of multidrug resistance in Acinetobacter baumannii.Kuo HY, Chang KC, Kuo JW, Yueh HW, Liou MLInt J Antimicrob Agents10.1016/j.ijantimicag.2011.08.0162011Acinetobacter Infections/microbiology, Acinetobacter baumannii/*drug effects/genetics/isolation & purification/metabolism, Anti-Bacterial Agents/*pharmacology, Bacterial Proteins/*genetics/metabolism, Carbapenems/pharmacology, Drug Resistance, Multiple, Bacterial/*drug effects/genetics, *Gene Expression Regulation, Bacterial, Humans, Imipenem/*pharmacology, Microbial Sensitivity Tests, Mutation, Nuclear Proteins, Reverse Transcriptase Polymerase Chain Reaction, Selection, Genetic, beta-Lactamases/genetics/metabolismMetabolism
Metabolism22024825Colistin-resistant, lipopolysaccharide-deficient Acinetobacter baumannii responds to lipopolysaccharide loss through increased expression of genes involved in the synthesis and transport of lipoproteins, phospholipids, and poly-beta-1,6-N-acetylglucosamine.Henry R, Vithanage N, Harrison P, Seemann T, Coutts S, Moffatt JH, Nation RL, Li J, Harper M, Adler B, Boyce JDAntimicrob Agents Chemother10.1128/AAC.05191-112011Acetylglucosamine/genetics/*metabolism, Acinetobacter Infections/drug therapy/microbiology, Acinetobacter baumannii/*drug effects/genetics/metabolism, Animals, Anti-Bacterial Agents/*pharmacology, Bacterial Secretion Systems/drug effects/*genetics, Biological Transport/drug effects, Colistin/*pharmacology, Drug Resistance, Bacterial/drug effects, Fimbriae Proteins/genetics/metabolism, Gene Expression Profiling, Gene Expression Regulation, Bacterial/drug effects, High-Throughput Nucleotide Sequencing, Lipopolysaccharides/deficiency, Lipoproteins/genetics/*metabolism, Mutation, Phospholipids/genetics/metabolismPathogenicity
Pathogenicity22068504Interaction of Acinetobacter baumannii 19606 and 1656-2 with Acanthamoeba castellanii.Tamang MD, Kim S, Kim SM, Kong HH, Kim JJ Microbiol10.1007/s12275-011-1063-82011Acanthamoeba castellanii/*microbiology/*physiology, Acinetobacter baumannii/growth & development/pathogenicity/*physiology, Bacterial Adhesion, Bacterial Toxins/analysis/toxicity, Cell Death, Cell Survival, Culture Media/chemistry, Humans, *Microbial InteractionsCultivation
Pathogenicity22089352Establishment of a novel target-based real-time quantitative PCR method for Acinetobacter baumannii detection.Zhang L, Ding G, Wei L, Pan X, Mei L, Zhang Y, Lu YDiagn Mol Pathol10.1097/PDM.0b013e31821bbb1e2011Acinetobacter Infections/diagnosis, Acinetobacter baumannii/genetics/*isolation & purification, *Bacterial Typing Techniques, Biofilms, DNA, Bacterial/analysis/genetics, Humans, Molecular Sequence Data, Polymerase Chain Reaction/*methods, Sensitivity and Specificity, Sequence Analysis, DNAGenetics
Pathogenicity22146875Growth phase-dependent expression of RND efflux pump- and outer membrane porin-encoding genes in Acinetobacter baumannii ATCC 19606.Fernando D, Kumar AJ Antimicrob Chemother10.1093/jac/dkr5192011Acinetobacter baumannii/drug effects/genetics/*growth & development/*metabolism, Bacterial Outer Membrane Proteins/*biosynthesis, Biological Transport, Active, *Drug Resistance, Multiple, Bacterial, Gene Expression Profiling, *Gene Expression Regulation, Bacterial, Porins/*biosynthesis, Real-Time Polymerase Chain ReactionMetabolism
Metabolism22232188Role of acinetobactin-mediated iron acquisition functions in the interaction of Acinetobacter baumannii strain ATCC 19606T with human lung epithelial cells, Galleria mellonella caterpillars, and mice.Gaddy JA, Arivett BA, McConnell MJ, Lopez-Rojas R, Pachon J, Actis LAInfect Immun10.1128/IAI.06279-112012Acinetobacter Infections/*microbiology/mortality/pathology, Acinetobacter baumannii/metabolism/*pathogenicity, Animals, Cell Line, Disease Models, Animal, Epithelial Cells/*microbiology, Female, Humans, Imidazoles/*metabolism, Iron/*metabolism, Larva/microbiology, Lepidoptera/microbiology, Mice, Mice, Inbred C57BL, Oxazoles/*metabolism, Sepsis/microbiology/mortality/pathology, Survival Analysis, Virulence Factors/*metabolismPathogenicity
Pathogenicity22240078Synergistic activity of coriander oil and conventional antibiotics against Acinetobacter baumannii.Duarte A, Ferreira S, Silva F, Domingues FCPhytomedicine10.1016/j.phymed.2011.11.0102012Acinetobacter baumannii/*drug effects, Anti-Bacterial Agents/*chemistry/pharmacology, Chloramphenicol/pharmacology, Ciprofloxacin/pharmacology, Coriandrum/*chemistry, Drug Synergism, Gentamicins/pharmacology, Microbial Sensitivity Tests, Piperacillin/pharmacology, Plant Oils/chemistry/*pharmacology, Tetracycline/pharmacology
Pathogenicity22290957Three-dimensional human skin equivalent as a tool to study Acinetobacter baumannii colonization.de Breij A, Haisma EM, Rietveld M, El Ghalbzouri A, van den Broek PJ, Dijkshoorn L, Nibbering PHAntimicrob Agents Chemother10.1128/AAC.05975-112012Acinetobacter/*drug effects/physiology, Acinetobacter baumannii/drug effects/physiology, Bacterial Adhesion/drug effects, Biofilms/*drug effects/growth & development, Cell Culture Techniques, Cell Differentiation/drug effects, Cell Proliferation/drug effects, Cell Separation, Chlorhexidine/pharmacology, Colony Count, Microbial, Cytokines/biosynthesis/immunology, Disinfectants/pharmacology, Gene Expression/drug effects, Humans, Keratinocytes/cytology/drug effects/immunology/*microbiology, Middle Aged, Skin/cytology/drug effects/immunology/*microbiology
Pathogenicity22309915New heterocyclic compounds from 1,2,4-triazole and 1,3,4-thiadiazole class bearing diphenylsulfone moieties. Synthesis, characterization and antimicrobial activity evaluation.Barbuceanu SF, Saramet G, Almajan GL, Draghici C, Barbuceanu F, Bancescu GEur J Med Chem10.1016/j.ejmech.2012.01.0312012Anti-Infective Agents/chemical synthesis/*chemistry/*pharmacology, Bacteria/drug effects, Bacterial Infections/drug therapy, Fungi/drug effects, Humans, Microbial Sensitivity Tests, Mycoses/drug therapy, Thiadiazoles/chemical synthesis/*chemistry/*pharmacology, Triazoles/chemical synthesis/*chemistry/*pharmacology
Metabolism22367951Acinetobacter baumannii outer membrane protein A modulates the biogenesis of outer membrane vesicles.Moon DC, Choi CH, Lee JH, Choi CW, Kim HY, Park JS, Kim SI, Lee JCJ Microbiol10.1007/s12275-012-1589-42012Acinetobacter baumannii/genetics/*metabolism, Bacterial Outer Membrane Proteins/genetics/*metabolism, Bacterial Proteins/metabolism, Biological Transport, Exosomes/*metabolism, Gene Knockout Techniques, Lipopolysaccharides/metabolism
Metabolism22467784Stress response and virulence functions of the Acinetobacter baumannii NfuA Fe-S scaffold protein.Zimbler DL, Park TM, Arivett BA, Penwell WF, Greer SM, Woodruff TM, Tierney DL, Actis LAJ Bacteriol10.1128/JB.00213-122012Acinetobacter Infections/metabolism/*microbiology, Acinetobacter baumannii/genetics/growth & development/*metabolism/*pathogenicity, Animals, Bacterial Proteins/genetics/*metabolism, Cell Line, Escherichia coli/genetics/metabolism, Humans, Hydrogen Peroxide/metabolism, Iron/metabolism, Iron-Sulfur Proteins/genetics/*metabolism, Molecular Sequence Data, Moths, *Oxidative Stress, Siderophores/metabolism, VirulencePathogenicity
Metabolism22570720The Acinetobacter baumannii entA gene located outside the acinetobactin cluster is critical for siderophore production, iron acquisition and virulence.Penwell WF, Arivett BA, Actis LAPLoS One10.1371/journal.pone.00364932012Acinetobacter baumannii/*genetics/*metabolism/pathogenicity, Chromosomes, Bacterial, Cloning, Molecular, Gene Order, *Genes, Bacterial, Genetic Loci, Imidazoles/metabolism, Iron/*metabolism, Molecular Sequence Annotation, Multigene Family, Oxazoles/metabolism, Phenotype, Siderophores/*biosynthesis, Virulence/geneticsEnzymology
Pathogenicity22751540In vitro synergy of colistin combinations against colistin-resistant Acinetobacter baumannii, Pseudomonas aeruginosa, and Klebsiella pneumoniae isolates.Vidaillac C, Benichou L, Duval REAntimicrob Agents Chemother10.1128/AAC.05996-112012Acinetobacter baumannii/*drug effects/growth & development/isolation & purification, Anti-Bacterial Agents/*pharmacology, Colistin/*pharmacology, Drug Resistance, Multiple, Bacterial/drug effects, Drug Synergism, Gram-Negative Bacterial Infections/microbiology, Humans, Klebsiella pneumoniae/*drug effects/growth & development/isolation & purification, Microbial Sensitivity Tests, Microbial Viability/drug effects, Pseudomonas aeruginosa/*drug effects/growth & development/isolation & purification, Trimethoprim, Sulfamethoxazole Drug Combination/*pharmacology, Vancomycin/*pharmacologyEnzymology
Phylogeny22781320[Changes in expression of gene aba I in biofilm of Acinetobacter baumannii strains isolated from burn patients].Xiang J, Sun Z, Yang XG, Huan JNZhonghua Shao Shang Za Zhi2012Acinetobacter Infections, Acinetobacter baumannii/*genetics/*isolation & purification, Biofilms, Burns/*microbiology, Drug Resistance, Bacterial, Genes, Bacterial, HumansPathogenicity
Pathogenicity23312607In vivo efficacy of telavancin/colistin combination therapy in a Galleria mellonella model of Acinetobacter baumannii infection.Hornsey M, Phee L, Longshaw C, Wareham DWInt J Antimicrob Agents10.1016/j.ijantimicag.2012.11.0132013Acinetobacter Infections/*drug therapy, Acinetobacter baumannii/*drug effects, Aminoglycosides/*administration & dosage, Animals, Anti-Bacterial Agents/*administration & dosage, Colistin/*administration & dosage, Disease Models, Animal, Drug Therapy, Combination/methods, Larva/microbiology, Lepidoptera/microbiology, Lipoglycopeptides, Survival Analysis, Treatment Outcome
23517882Cryo-electron tomography analysis of membrane vesicles from Acinetobacter baumannii ATCC19606 T.Koning RI, de Breij A, Oostergetel GT, Nibbering PH, Koster AJ, Dijkshoorn LRes Microbiol10.1016/j.resmic.2013.02.0072013Acinetobacter baumannii/*ultrastructure, Cryoelectron Microscopy, Electron Microscope Tomography, Secretory Vesicles/*ultrastructure
Pathogenicity23609511In vitro activity of daptomycin in combination with low-dose colistin against a diverse collection of Gram-negative bacterial pathogens.Phee L, Hornsey M, Wareham DWEur J Clin Microbiol Infect Dis10.1007/s10096-013-1875-z2013Colistin/*pharmacology, Daptomycin/*pharmacology, *Drug Synergism, Gram-Negative Bacteria/*drug effects/isolation & purification, Gram-Negative Bacterial Infections/microbiology, Humans, Microbial Sensitivity TestsEnzymology
Metabolism23817614Functional features of TonB energy transduction systems of Acinetobacter baumannii.Zimbler DL, Arivett BA, Beckett AC, Menke SM, Actis LAInfect Immun10.1128/IAI.00540-132013Acinetobacter baumannii/genetics/*metabolism/*pathogenicity, Amino Acid Sequence, Bacterial Proteins/*genetics/*metabolism, Biological Transport, Active, Cell Line, Energy Transfer, Escherichia coli/genetics/metabolism, Escherichia coli Proteins/genetics/metabolism, Genes, Bacterial, Humans, Iron/metabolism, Membrane Proteins/*genetics/*metabolism, Molecular Sequence Data, Operon/genetics, Phylogeny, Sequence Alignment, Virulence/geneticsPathogenicity
Pathogenicity23977136Acinetobacter baumannii outer membrane vesicles elicit a potent innate immune response via membrane proteins.Jun SH, Lee JH, Kim BR, Kim SI, Park TI, Lee JC, Lee YCPLoS One10.1371/journal.pone.00717512013Acinetobacter baumannii/drug effects/*immunology, Animals, Bacterial Outer Membrane Proteins/*immunology, Cell Line, Cell Membrane/drug effects/metabolism, Cytokines/metabolism, Edetic Acid/pharmacology, Endopeptidase K/pharmacology, Epithelial Cells/drug effects/immunology/microbiology/pathology, Female, Humans, Immunity, Innate/drug effects/*immunology, Inflammation/pathology, Mice, Mice, Inbred BALB C, Mutation/genetics, Secretory Vesicles/drug effects/*immunologyMetabolism
Pathogenicity23979736Homeostasis of glutathione is associated with polyamine-mediated beta-lactam susceptibility in Acinetobacter baumannii ATCC 19606.Kwon DH, Hekmaty S, Seecoomar GAntimicrob Agents Chemother10.1128/AAC.00692-132013Acinetobacter baumannii/*drug effects/genetics/metabolism, Aztreonam/pharmacology, Biological Transport/drug effects, Carbenicillin/pharmacology, DNA Transposable Elements, Drug Resistance, Multiple, Bacterial/*drug effects/genetics, *Genes, Bacterial, Glutathione/*metabolism, Homeostasis, Membrane Transport Proteins/*genetics/metabolism, Mutagenesis, Oxidation-Reduction, Spermidine/*pharmacology, Spermine/*pharmacology, beta-Lactams/pharmacologyMetabolism
Pathogenicity24103863Holarrhena antidysenterica as a resistance modifying agent against Acinetobacter baumannii: Its effects on bacterial outer membrane permeability and efflux pumps.Chusri S, Na-Phatthalung P, Siriyong T, Paosen S, Voravuthikunchai SPMicrobiol Res10.1016/j.micres.2013.09.0042013Acinetobacter baumannii/*drug effects, Anti-Bacterial Agents/isolation & purification/metabolism/*pharmacology, Biological Transport, Active/*drug effects, Cell Membrane Permeability/*drug effects, Drug Resistance, Bacterial/*drug effects, Drug Synergism, Holarrhena/*chemistry, Microbial Sensitivity Tests, Novobiocin/metabolism/pharmacology, Plant Extracts/isolation & purification/*pharmacologyEnzymology
Pathogenicity24189257Biological cost of different mechanisms of colistin resistance and their impact on virulence in Acinetobacter baumannii.Beceiro A, Moreno A, Fernandez N, Vallejo JA, Aranda J, Adler B, Harper M, Boyce JD, Bou GAntimicrob Agents Chemother10.1128/AAC.01597-132013Acinetobacter baumannii/*drug effects/*pathogenicity, Animals, Cell Line, Colistin/*pharmacology/*therapeutic use, Drug Resistance, Bacterial, Female, Humans, Mice, Mice, Inbred BALB C, Virulence
Pathogenicity24369483Xuebijing Protects Rats from Sepsis Challenged with Acinetobacter baumannii by Promoting Annexin A1 Expression and Inhibiting Proinflammatory Cytokines Secretion.He XD, Wang Y, Wu Q, Wang HX, Chen ZD, Zheng RS, Wang ZS, Wang JB, Yang YEvid Based Complement Alternat Med10.1155/2013/8049402013
Enzymology24644055Pathogenicity of ocular isolates of Acinetobacter baumannii in a mouse model of bacterial endophthalmitis.Talreja D, Kaye KS, Yu FS, Walia SK, Kumar AInvest Ophthalmol Vis Sci10.1167/iovs.13-134012014Acinetobacter Infections/diagnosis/*microbiology/physiopathology, Acinetobacter baumannii/genetics/isolation & purification/*pathogenicity, Animals, Apoptosis, Disease Models, Animal, Electroretinography, Endophthalmitis/diagnosis/*microbiology/physiopathology, Eye Infections, Bacterial/diagnosis/*microbiology/physiopathology, Female, Flow Cytometry, In Situ Nick-End Labeling, Mice, Mice, Inbred C57BL, RNA, Bacterial/analysis, Real-Time Polymerase Chain Reaction, Retina/microbiology/pathology/*physiopathology, Severity of Illness IndexPhylogeny
Metabolism24837410Bactericidal effect of sulbactam against Acinetobacter baumannii ATCC 19606 studied by 2D-DIGE and mass spectrometry.Lin CH, Su SC, Ho KH, Hsu YW, Lee KRInt J Antimicrob Agents10.1016/j.ijantimicag.2014.03.0042014ATP-Binding Cassette Transporters/genetics/metabolism, Acinetobacter baumannii/*drug effects/genetics/metabolism, Anti-Bacterial Agents/*pharmacology, Bacterial Proteins/*genetics/metabolism, *Gene Expression Regulation, Bacterial, Mass Spectrometry, Metabolic Networks and Pathways/drug effects/genetics, Molecular Sequence Annotation, Proteome/*genetics/metabolism, Ribosomal Proteins/genetics/metabolism, Ribosome Subunits, Large, Bacterial/drug effects/genetics/metabolism, Ribosome Subunits, Small, Bacterial/drug effects/genetics/metabolism, Sulbactam/*pharmacology, Two-Dimensional Difference Gel ElectrophoresisPathogenicity
Enzymology24910020CpaA a novel protease from Acinetobacter baumannii clinical isolates deregulates blood coagulation.Tilley D, Law R, Warren S, Samis JA, Kumar AFEMS Microbiol Lett10.1111/1574-6968.124962014Acinetobacter Infections/*blood/microbiology, Acinetobacter baumannii/*enzymology/isolation & purification, Bacterial Proteins/chemistry/*physiology, Blood Coagulation, Catalytic Domain, Conserved Sequence, Fibrinogen/chemistry, Humans, Metalloendopeptidases/chemistry/*physiology, Partial Thromboplastin Time, Proteolysis, Sequence Analysis, ProteinPathogenicity
Enzymology24934340Chemical constituents and antimicrobial properties of the essential oil and ethanol extract from the stem of Aglaia odorata Lour.Joycharat N, Thammavong S, Voravuthikunchai SP, Plodpai P, Mitsuwan W, Limsuwan S, Subhadhirasakul SNat Prod Res10.1080/14786419.2014.9249342014Aglaia/*chemistry, Anti-Bacterial Agents/chemistry/*isolation & purification/*pharmacology, Antifungal Agents/chemistry/*isolation & purification/*pharmacology, Gas Chromatography-Mass Spectrometry, Gram-Negative Bacteria/drug effects, Ketones/chemistry/isolation & purification/pharmacology, Microbial Sensitivity Tests, Monocyclic Sesquiterpenes, Oils, Volatile/*chemistry/*pharmacology, Oryza/microbiology, Plant Stems/chemistry, Polycyclic Sesquiterpenes, Sesquiterpenes/chemistry/*isolation & purification/*pharmacology, Sesquiterpenes, Germacrane/chemistry/isolation & purification/pharmacology, Staphylococcus aureus/drug effects, StereoisomerismPhylogeny
25001601Severe Acinetobacter baumannii sepsis is associated with elevation of pentraxin 3.Ketter PM, Guentzel MN, Schaffer B, Herzig M, Wu X, Montgomery RK, Parida BK, Fedyk CG, Yu JJ, Jorgensen J, Chambers JP, Cap AP, Arulanandam BPInfect Immun10.1128/IAI.01958-142014Acinetobacter Infections/blood/immunology/microbiology, Acinetobacter baumannii/*immunology, Animals, C-Reactive Protein/*immunology, Cell Line, Chemokines/blood, Macrophages/immunology/microbiology, Mice, Mice, Inbred C57BL, Monocytes/immunology/microbiology, Nerve Tissue Proteins/blood/*immunology, Neutrophils/immunology/microbiology, Peroxidase/blood, Sepsis/blood/*immunology/microbiology, Shock, Septic/blood/*immunology/mortality
Pathogenicity25039371Incubation temperature, osmolarity, and salicylate affect the expression of resistance-nodulation-division efflux pumps and outer membrane porins in Acinetobacter baumannii ATCC19606T.Bazyleu A, Kumar AFEMS Microbiol Lett10.1111/1574-6968.125302014Acinetobacter baumannii/*drug effects/*radiation effects, Drug Resistance, Bacterial, Gene Expression Profiling, Gene Expression Regulation, Bacterial/*drug effects/*radiation effects, Membrane Transport Proteins/*biosynthesis, *Osmolar Concentration, Real-Time Polymerase Chain Reaction, Salicylates/*metabolism, TemperatureMetabolism
Pathogenicity25066394Synergistic effects of ethnomedicinal plants of Apocynaceae family and antibiotics against clinical isolates of Acinetobacter baumannii.Chusri S, Siriyong T, Na-Phatthalung P, Voravuthikunchai SPAsian Pac J Trop Med10.1016/S1995-7645(14)60074-22014Acinetobacter Infections/*microbiology, Acinetobacter baumannii/*drug effects, Anti-Bacterial Agents/*pharmacology, Apocynaceae/*chemistry, Drug Resistance, Multiple, Bacterial, Drug Synergism, Drug Therapy, Combination, Humans, Microbial Viability/drug effects, Plant Extracts/*pharmacology
Pathogenicity25068263Recombinant scorpine produced using SUMO fusion partner in Escherichia coli has the activities against clinically isolated bacteria and inhibits the Plasmodium falciparum parasitemia in vitro.Zhang C, He X, Gu Y, Zhou H, Cao J, Gao QPLoS One10.1371/journal.pone.01034562014Acinetobacter baumannii/drug effects, Animals, Anti-Bacterial Agents/isolation & purification/metabolism/pharmacology, Antiprotozoal Agents/isolation & purification/metabolism/pharmacology, Bacteria/*drug effects, Blotting, Western, Escherichia coli/genetics, Humans, Microbial Sensitivity Tests, Parasitemia/parasitology/prevention & control, Parasitic Sensitivity Tests, Plasmodium falciparum/*drug effects, Recombinant Fusion Proteins/isolation & purification/*metabolism/*pharmacology, Scorpions/genetics/*metabolism, Small Ubiquitin-Related Modifier Proteins/genetics/*metabolism, Staphylococcal Infections/microbiology, Staphylococcus aureus/drug effectsMetabolism
Metabolism25086432The role of filamentous hemagglutinin adhesin in adherence and biofilm formation in Acinetobacter baumannii ATCC19606(T).Darvish Alipour Astaneh S, Rasooli I, Mousavi Gargari SLMicrob Pathog10.1016/j.micpath.2014.07.0072014Acinetobacter baumannii/cytology/genetics/immunology/*physiology, Adhesins, Bacterial/genetics/immunology/*metabolism, Animals, Antibodies, Bacterial/blood, Antigens, Bacterial/genetics/immunology/metabolism, *Bacterial Adhesion, Biofilms/*growth & development, Cell Line, Epithelial Cells/microbiology, Escherichia coli/genetics/isolation & purification/metabolism, Gene Deletion, Hemagglutinins/genetics/immunology/*metabolism, Humans, Mice, Recombinant Proteins/genetics/immunology/isolation & purification/metabolismEnzymology
25146140Draft Genome Assembly of Acinetobacter baumannii ATCC 19606.Davenport KW, Daligault HE, Minogue TD, Bruce DC, Chain PS, Coyne SR, Jaissle JG, Koroleva GI, Ladner JT, Li PE, Palacios GF, Scholz MB, Teshima H, Johnson SLGenome Announc10.1128/genomeA.00832-142014
Proteome25171011Development and characterization of monoclonal antibodies for rapid detection of Acinetobacter baumannii.Baig A, Cabral TM, Corbett CRMonoclon Antib Immunodiagn Immunother10.1089/mab.2013.00732014Acinetobacter Infections/*diagnosis, Acinetobacter baumannii/*immunology, Animals, Antibodies, Monoclonal, Murine-Derived/*immunology, Blotting, Western, Chromatography, Liquid, Cross Reactions/immunology, Enzyme-Linked Immunosorbent Assay, Hybridomas/immunology, Immunoblotting, Immunoprecipitation, Mice, Tandem Mass Spectrometry
Metabolism25351948Mutant prevention concentrations of levofloxacin, pazufloxacin and ciprofloxacin for A. baumannii and mutations in gyrA and parC genes.Sun C, Hao J, Dou M, Gong YJ Antibiot (Tokyo)10.1038/ja.2014.1502014Acinetobacter baumannii/*drug effects/genetics, Anti-Bacterial Agents/pharmacology, Ciprofloxacin/*pharmacology, DNA Gyrase/genetics/*metabolism, DNA Topoisomerase IV/genetics/*metabolism, DNA, Bacterial/genetics, Fluoroquinolones/*pharmacology, Gene Expression Regulation, Bacterial/physiology, Levofloxacin/*pharmacology, Microbial Sensitivity Tests, Mutation, Oxazines/*pharmacologyPathogenicity
Enzymology25440154In vivo activity of daptomycin/colistin combination therapy in a Galleria mellonella model of Acinetobacter baumannii infection.Yang H, Chen G, Hu L, Liu Y, Cheng J, Li H, Ye Y, Li JInt J Antimicrob Agents10.1016/j.ijantimicag.2014.10.0122014Acinetobacter Infections/*drug therapy/microbiology, Acinetobacter baumannii/*isolation & purification, Animals, Anti-Bacterial Agents/administration & dosage/*therapeutic use, Colistin/administration & dosage/*therapeutic use, Daptomycin/administration & dosage/*therapeutic use, *Disease Models, Animal, Drug Therapy, Combination, LepidopteraPhylogeny
Pathogenicity25485716Immunization with lipopolysaccharide-deficient whole cells provides protective immunity in an experimental mouse model of Acinetobacter baumannii infection.Garcia-Quintanilla M, Pulido MR, Pachon J, McConnell MJPLoS One10.1371/journal.pone.01144102014Acinetobacter Infections/immunology/microbiology/*prevention & control, Acinetobacter baumannii/*immunology, Animals, Bacterial Load, Bacterial Vaccines/*therapeutic use, Disease Models, Animal, Female, Humans, Immunization, Lipopolysaccharides/*deficiency/immunology, Mice, Mice, Inbred BALB C, Mice, Inbred C57BL, Sepsis/immunology/microbiology/*prevention & control
Metabolism25605767Role of the carboxy terminus of SecA in iron acquisition, protein translocation, and virulence of the bacterial pathogen Acinetobacter baumannii.Fiester SE, Nwugo CC, Penwell WF, Neary JM, Beckett AC, Arivett BA, Schmidt RE, Geiger SC, Connerly PL, Menke SM, Tomaras AP, Actis LAInfect Immun10.1128/IAI.02925-1420152,2'-Dipyridyl/chemistry, Acinetobacter Infections/microbiology, Acinetobacter baumannii/genetics/metabolism/*pathogenicity, Adenosine Triphosphatases/genetics/*metabolism, Animals, Bacterial Outer Membrane Proteins/biosynthesis/metabolism, Bacterial Proteins/genetics/*metabolism, Imidazoles/metabolism, Ion Channels/*genetics/metabolism, Iron/chemistry/*metabolism, Membrane Transport Proteins/genetics/*metabolism, Moths/microbiology, Mutation, Oxazoles/metabolism, Protein Transport/genetics/physiology, SEC Translocation Channels, SecA Proteins, Virulence Factors/genetics
Pathogenicity25645842Novel approach to optimize synergistic carbapenem-aminoglycoside combinations against carbapenem-resistant Acinetobacter baumannii.Yadav R, Landersdorfer CB, Nation RL, Boyce JD, Bulitta JBAntimicrob Agents Chemother10.1128/AAC.04379-142015Acinetobacter Infections/drug therapy/microbiology, Acinetobacter baumannii/*drug effects/growth & development, Aminoglycosides/pharmacokinetics/*pharmacology, Anti-Bacterial Agents/pharmacokinetics/*pharmacology, Carbapenems/pharmacokinetics/*pharmacology, Colony Count, Microbial, Computer Simulation, Drug Combinations, Drug Resistance, Bacterial, Drug Synergism, Humans, Microbial Sensitivity Tests, Monte Carlo MethodEnzymology
Metabolism25677974Heterologous expression of 3-O-deacylase in Acinetobacter baumannii modulates the endotoxicity of lipopolysaccharide.Badmasti F, Shahcheraghi F, Siadat SD, Bouzari S, Ajdary S, Amin M, Halabian R, Imani Fooladi AAJ Mol Microbiol Biotechnol10.1159/0003718152015Acinetobacter baumannii/*enzymology/genetics/*metabolism, Animals, Carboxylic Ester Hydrolases/genetics/*metabolism, Cell Line, Electroporation, Endotoxins/immunology/metabolism/*toxicity, Gene Expression, Interleukin-6/biosynthesis, Lipopolysaccharides/immunology/metabolism/*toxicity, Macrophages/immunology, Mice, Recombinant Proteins/genetics/metabolism, Transformation, BacterialEnzymology
Pathogenicity25714496Biofilm Formation and Colistin Susceptibility of Acinetobacter baumannii Isolated from Korean Nosocomial Samples.Kim HA, Ryu SY, Seo I, Suh SI, Suh MH, Baek WKMicrob Drug Resist10.1089/mdr.2014.02362015Acinetobacter Infections/*microbiology, Acinetobacter baumannii/*drug effects, Anti-Bacterial Agents/*pharmacology, Biofilms/drug effects/*growth & development, Colistin/*pharmacology, Cross Infection/*microbiology, Drug Resistance, Bacterial, Humans, Microbial Sensitivity Tests, Republic of KoreaPhylogeny
Pathogenicity25746991Simple Method for Markerless Gene Deletion in Multidrug-Resistant Acinetobacter baumannii.Oh MH, Lee JC, Kim J, Choi CH, Han KAppl Environ Microbiol10.1128/AEM.03975-142015Acinetobacter Infections/microbiology, Acinetobacter baumannii/drug effects/*genetics/metabolism, Anti-Bacterial Agents/pharmacology, Bacterial Proteins/*genetics/metabolism, Drug Resistance, Bacterial, *Gene Deletion, Genetic Markers, *Genetic Techniques, HumansMetabolism
Pathogenicity25888221Enhancing pili assembly and biofilm formation in Acinetobacter baumannii ATCC19606 using non-native acyl-homoserine lactones.Luo LM, Wu LJ, Xiao YL, Zhao D, Chen ZX, Kang M, Zhang Q, Xie YBMC Microbiol10.1186/s12866-015-0397-52015Acinetobacter baumannii/*drug effects/growth & development/metabolism/physiology, Acyl-Butyrolactones/*metabolism, Biofilms/*drug effects/growth & development, Fimbriae, Bacterial/*drug effects/ultrastructure, Gene Expression Profiling, Locomotion/*drug effects, Microscopy, Confocal, Microscopy, Electron, Transmission, *Organelle Biogenesis, Real-Time Polymerase Chain ReactionMetabolism
26213382Optimisation of the Caenorhabditis elegans model for studying the pathogenesis of opportunistic Acinetobacter baumannii.Vallejo JA, Beceiro A, Rumbo-Feal S, Rodriguez-Palero MJ, Russo TA, Bou GInt J Antimicrob Agents10.1016/j.ijantimicag.2015.05.0212015
Metabolism26224347Phoenix dactylifera (date palm) pit aqueous extract mediated novel route for synthesis high stable silver nanoparticles with high antifungal and antibacterial activity.Khatami M, Pourseyedi SIET Nanobiotechnol10.1049/iet-nbt.2014.00522015Acinetobacter baumannii/drug effects, Anti-Bacterial Agents/*chemistry/metabolism, Antifungal Agents/*chemistry/metabolism, Biotechnology, Metal Nanoparticles/*chemistry, Microbial Viability/drug effects, Nanotechnology, Phoeniceae/*chemistry, Plant Extracts/*chemistry/metabolism, Rhizoctonia/drug effects, Silver/*chemistry/metabolismPathogenicity
Metabolism26277277Immunological evaluation of OMV(PagL)+Bap(1-487aa) and AbOmpA(8-346aa)+Bap(1-487aa) as vaccine candidates against Acinetobacter baumannii sepsis infection.Badmasti F, Ajdary S, Bouzari S, Fooladi AA, Shahcheraghi F, Siadat SDMol Immunol10.1016/j.molimm.2015.07.0312015Acinetobacter Infections/*immunology/microbiology, Acinetobacter baumannii/*immunology, Animals, Antibody Formation/immunology, Bacterial Load/immunology, Bacterial Outer Membrane Proteins/*immunology, Bacterial Vaccines/immunology, Female, Immunization, Immunoglobulin G/immunology, Interferon-gamma/metabolism, Interleukin-4/metabolism, Kaplan-Meier Estimate, Mice, Inbred C57BL, Sepsis/*immunology/*microbiology, Spleen/microbiology/pathology
Metabolism26379240Acinetobacter baumannii Virulence Is Mediated by the Concerted Action of Three Phospholipases D.Stahl J, Bergmann H, Gottig S, Ebersberger I, Averhoff BPLoS One10.1371/journal.pone.01383602015Acinetobacter Infections/metabolism/microbiology, Acinetobacter baumannii/*metabolism, Bacterial Proteins/metabolism, Cell Line, Cell Membrane/metabolism/microbiology, Epithelial Cells/metabolism/microbiology, Humans, Phospholipase D/*metabolism, Virulence/*physiology, Virulence Factors/*metabolismPathogenicity
Pathogenicity26416873Antimicrobial Activity of Gallium Protoporphyrin IX against Acinetobacter baumannii Strains Displaying Different Antibiotic Resistance Phenotypes.Arivett BA, Fiester SE, Ohneck EJ, Penwell WF, Kaufman CM, Relich RF, Actis LAAntimicrob Agents Chemother10.1128/AAC.01472-152015Acinetobacter Infections/drug therapy/microbiology, Acinetobacter baumannii/*drug effects/growth & development/metabolism, Animals, Anti-Bacterial Agents/chemistry/*pharmacology, Cell Line, Tumor, Coordination Complexes/chemistry/*pharmacology, Drug Resistance, Multiple, Bacterial/*drug effects, Epithelial Cells/drug effects/microbiology, Gallium/chemistry/*pharmacology, Humans, Iron/metabolism, Larva/drug effects/microbiology, Microbial Sensitivity Tests, Microbial Viability/drug effects, Moths/drug effects/microbiology, Phenotype, Protoporphyrins/chemistry/*pharmacology, Survival AnalysisPhenotype
26617588Genotypic and Antimicrobial Susceptibility of Carbapenem-resistant Acinetobacter baumannii: Analysis of is Aba Elements and bla OXA-23-like Genes Including a New Variant.Bahador A, Raoofian R, Pourakbari B, Taheri M, Hashemizadeh Z, Hashemi FBFront Microbiol10.3389/fmicb.2015.012492015
Enzymology26660878Prevalence of hypermutators among clinical Acinetobacter baumannii isolates.Komp Lindgren P, Higgins PG, Seifert H, Cars OJ Antimicrob Chemother10.1093/jac/dkv3782015Acinetobacter Infections/*microbiology, Acinetobacter baumannii/*drug effects/*genetics/isolation & purification, Anti-Bacterial Agents/*pharmacology, Disk Diffusion Antimicrobial Tests, *Drug Resistance, Bacterial, *Mutation Rate, Rifampin/*pharmacologyPhylogeny
Metabolism26668262Characterization of an Acinetobacter baumannii lptD Deletion Strain: Permeability Defects and Response to Inhibition of Lipopolysaccharide and Fatty Acid Biosynthesis.Bojkovic J, Richie DL, Six DA, Rath CM, Sawyer WS, Hu Q, Dean CRJ Bacteriol10.1128/JB.00639-152015Acinetobacter baumannii/*genetics/*metabolism, Bacterial Outer Membrane Proteins/*genetics/metabolism, Biological Transport, Cell Membrane/metabolism, Fatty Acids/*biosynthesis, *Gene Deletion, Gene Expression Regulation, Bacterial, Lipopolysaccharides/*biosynthesis, Permeability
Pathogenicity26725481Activity of levofloxacin in combination with colistin against Acinetobacter baumannii: In vitro and in a Galleria mellonella model.Wei W, Yang H, Hu L, Ye Y, Li JJ Microbiol Immunol Infect10.1016/j.jmii.2015.10.0102015Acinetobacter baumannii/*drug effects/isolation & purification, Animals, Anti-Bacterial Agents/*pharmacology, Biofilms/drug effects/*growth & development, Colistin/*pharmacology, Drug Combinations, Drug Resistance, Bacterial, Drug Synergism, Humans, Levofloxacin/*pharmacology, Microbial Sensitivity Tests, Moths/*microbiologyEnzymology
Metabolism26775400Immunogenicity of conserved cork and beta-barrel domains of baumannii acinetobactin utilization protein in an animal model.Sangroodi YH, Rasooli I, Nazarian S, Ebrahimizadeh W, Sefid FTurk J Med Sci10.3906/sag-1407-452015Acinetobacter baumannii/*immunology, Animals, Bacterial Outer Membrane Proteins/metabolism/*pharmacology, Injections, Intraperitoneal, Liver/microbiology/pathology, Mice, Inbred BALB C, Models, Animal, Rabbits, Recombinant Proteins/*pharmacology, Spleen/microbiology/pathology
Pathogenicity26872882The long-term survival of Acinetobacter baumannii ATCC 19606(T) under nutrient-deprived conditions does not require the entry into the viable but non-culturable state.Bravo Z, Orruno M, Parada C, Kaberdin VR, Barcina I, Arana IArch Microbiol10.1007/s00203-016-1200-12016Acinetobacter baumannii/drug effects/*physiology, Biofilms, Culture Media/pharmacology, *Microbial Viability/drug effects, Temperature, Water/metabolismCultivation
Enzymology26910023Screening of Herbal-Based Bioactive Extract Against Carbapenem-Resistant Strain of Acinetobacter baumannii.Tiwari M, Roy R, Tiwari VMicrob Drug Resist10.1089/mdr.2015.02702016Acinetobacter Infections/microbiology, Acinetobacter baumannii/*drug effects/growth & development/isolation & purification, Aegle/*chemistry, Alkaloids/isolation & purification, Anti-Bacterial Agents/chemistry/*pharmacology, Calotropis/*chemistry, Curcuma/chemistry, Drug Combinations, Drug Synergism, Glycosides/isolation & purification, Humans, Imipenem/*pharmacology, Microbial Sensitivity Tests, Phenols/isolation & purification, Plant Extracts/chemistry/*pharmacology, Plant Leaves/chemistry, Tannins/isolation & purification, beta-Lactam Resistance/*drug effects/physiologyPhylogeny
Metabolism26924392Global metabolic analyses identify key differences in metabolite levels between polymyxin-susceptible and polymyxin-resistant Acinetobacter baumannii.Maifiah MH, Cheah SE, Johnson MD, Han ML, Boyce JD, Thamlikitkul V, Forrest A, Kaye KS, Hertzog P, Purcell AW, Song J, Velkov T, Creek DJ, Li JSci Rep10.1038/srep222872016Acinetobacter baumannii/*drug effects/genetics/*metabolism, Anti-Bacterial Agents/*pharmacology, Cluster Analysis, *Drug Resistance, Bacterial, Drug Resistance, Multiple, Bacterial, Energy Metabolism/drug effects, Genomics/methods, Lipid A/chemistry/metabolism, Mass Spectrometry, *Metabolome, *Metabolomics/methods, Microbial Sensitivity Tests, Polymyxins/*pharmacologyPathogenicity
26998253Antibacterial Low Molecular Weight Cationic Polymers: Dissecting the Contribution of Hydrophobicity, Chain Length and Charge to Activity.Grace JL, Huang JX, Cheah SE, Truong NP, Cooper MA, Li J, Davis TP, Quinn JF, Velkov T, Whittaker MRRSC Adv10.1039/C5RA24361K2016
Enzymology27001819Effects of Saline, an Ambient Acidic Environment, and Sodium Salicylate on OXA-Mediated Carbapenem Resistance in Acinetobacter baumannii.Zander E, Seifert H, Higgins PGAntimicrob Agents Chemother10.1128/AAC.03010-152016Acinetobacter baumannii/*drug effects/*enzymology/genetics, Anti-Bacterial Agents/*pharmacology, Carbapenems/*pharmacology, Drug Resistance, Bacterial/genetics, Hydrogen-Ion Concentration, Microbial Sensitivity Tests, Reverse Transcriptase Polymerase Chain Reaction, Sodium Chloride/*pharmacology, Sodium Salicylate/*pharmacology, beta-Lactamases/*metabolismPathogenicity
Metabolism27085593Isolation, identification and diesel-oil biodegradation capacities of indigenous hydrocarbon-degrading strains of Cellulosimicrobium cellulans and Acinetobacter baumannii from tarball at Terengganu beach, Malaysia.Nkem BM, Halimoon N, Yusoff FM, Johari WLW, Zakaria MP, Medipally SR, Kannan NMar Pollut Bull10.1016/j.marpolbul.2016.03.0602016Acinetobacter baumannii/*metabolism, Biodegradation, Environmental, Environmental Microbiology, Hydrocarbons/*metabolism, Malaysia, Petroleum/*metabolism, RNA, Ribosomal, 16S/geneticsPhylogeny
Pathogenicity27148178Relationship between Antibiotic Resistance, Biofilm Formation, and Biofilm-Specific Resistance in Acinetobacter baumannii.Qi L, Li H, Zhang C, Liang B, Li J, Wang L, Du X, Liu X, Qiu S, Song HFront Microbiol10.3389/fmicb.2016.004832016
Pathogenicity27179817Impaired growth under iron-limiting conditions associated with the acquisition of colistin resistance in Acinetobacter baumannii.Lopez-Rojas R, Garcia-Quintanilla M, Labrador-Herrera G, Pachon J, McConnell MJInt J Antimicrob Agents10.1016/j.ijantimicag.2016.03.0102016Acinetobacter baumannii/*drug effects/*growth & development, Anti-Bacterial Agents/*pharmacology, Bacterial Proteins/genetics, Colistin/*pharmacology, Culture Media/chemistry, *Drug Resistance, Bacterial, Humans, Iron/*metabolism, Microbial Sensitivity Tests, Microbial Viability/drug effects, Mutation, Serum/chemistry, Transcription Factors/geneticsCultivation
Pathogenicity27195897Polymyxin Resistance in Acinetobacter baumannii: Genetic Mutations and Transcriptomic Changes in Response to Clinically Relevant Dosage Regimens.Cheah SE, Johnson MD, Zhu Y, Tsuji BT, Forrest A, Bulitta JB, Boyce JD, Nation RL, Li JSci Rep10.1038/srep262332016Acinetobacter Infections/microbiology, Acinetobacter baumannii/*drug effects/*genetics/growth & development/isolation & purification, Anti-Bacterial Agents/*pharmacology, Bacterial Proteins/genetics, Colony Count, Microbial, *Drug Resistance, Bacterial, Gene Expression Profiling, *Gene Expression Regulation, Bacterial, Genomics, Humans, Microbial Viability/drug effects, *Mutation, Polymyxins/*pharmacology, Time Factors, Transcription Factors/geneticsGenetics
Pathogenicity27234880Aptamer-nanobody based ELASA for specific detection of Acinetobacter baumannii isolates.Rasoulinejad S, Gargari SLMJ Biotechnol10.1016/j.jbiotec.2016.05.0242016Acinetobacter Infections/diagnosis/microbiology, Acinetobacter baumannii/*genetics/*isolation & purification, Aptamers, Nucleotide/chemistry/*genetics, DNA, Bacterial/analysis/*genetics, Flow Cytometry, Humans, Limit of Detection, SELEX Aptamer Technique/*methodsEnzymology
Pathogenicity27444886Modulation of virulence in Acinetobacter baumannii cells surviving photodynamic treatment with toluidine blue.Pourhajibagher M, Boluki E, Chiniforush N, Pourakbari B, Farshadzadeh Z, Ghorbanzadeh R, Aziemzadeh M, Bahador APhotodiagnosis Photodyn Ther10.1016/j.pdpdt.2016.07.0072016Acinetobacter baumannii/*drug effects/*pathogenicity/radiation effects, Cell Survival/*drug effects/physiology/radiation effects, Disinfection/methods, Dose-Response Relationship, Drug, Dose-Response Relationship, Radiation, Drug Therapy, Combination/methods, Humans, Photochemotherapy/*methods, Photosensitizing Agents/administration & dosage, Tolonium Chloride/*administration & dosage, Virulence/*drug effects/physiology
Pathogenicity27449542Combinatorial pharmacodynamics of polymyxin B and tigecycline against heteroresistant Acinetobacter baumannii.Rao GG, Ly NS, Diep J, Forrest A, Bulitta JB, Holden PN, Nation RL, Li J, Tsuji BTInt J Antimicrob Agents10.1016/j.ijantimicag.2016.06.0062016Acinetobacter baumannii/*drug effects, Anti-Bacterial Agents/*pharmacology, *Drug Resistance, Bacterial, *Drug Synergism, Microbial Sensitivity Tests, Microbial Viability/drug effects, Minocycline/*analogs & derivatives/pharmacology, Polymyxin B/*pharmacology, Tigecycline, Time Factors
Pathogenicity274832905-Episinuleptolide Decreases the Expression of the Extracellular Matrix in Early Biofilm Formation of Multi-Drug Resistant Acinetobacter baumannii.Tseng SP, Hung WC, Huang CY, Lin YS, Chan MY, Lu PL, Lin L, Sheu JHMar Drugs10.3390/md140801432016Acinetobacter Infections/microbiology/*prevention & control, Acinetobacter baumannii/*drug effects/physiology/ultrastructure, Animals, Anthozoa/*chemistry, Anti-Bacterial Agents/chemistry/isolation & purification/*pharmacology, Biofilms/*drug effects, Biological Products/isolation & purification/pharmacology, Cross Infection/microbiology/*prevention & control, Diterpenes/chemistry/isolation & purification/*pharmacology, *Drug Resistance, Multiple, Bacterial, Drug Synergism, Equipment Contamination, Extracellular Matrix/drug effects/ultrastructure, Genes, Bacterial/drug effects, Humans, Levofloxacin/pharmacology, Microscopy, Electron, Scanning, beta-Glucans/metabolismEnzymology
Pathogenicity27494922Polymyxin B in combination with doripenem against heteroresistant Acinetobacter baumannii: pharmacodynamics of new dosing strategies.Rao GG, Ly NS, Bulitta JB, Soon RL, San Roman MD, Holden PN, Landersdorfer CB, Nation RL, Li J, Forrest A, Tsuji BTJ Antimicrob Chemother10.1093/jac/dkw2932016Acinetobacter Infections/*drug therapy/microbiology, Acinetobacter baumannii/*drug effects, Anti-Bacterial Agents/*administration & dosage/pharmacokinetics/pharmacology, Carbapenems/*administration & dosage/pharmacokinetics/pharmacology, Doripenem, Drug Resistance, Bacterial, Drug Therapy, Combination/methods, Humans, Microbial Viability/drug effects, Models, Theoretical, Polymyxin B/*administration & dosage/pharmacokinetics/pharmacologyEnzymology
Metabolism27526195Toxic Accumulation of LPS Pathway Intermediates Underlies the Requirement of LpxH for Growth of Acinetobacter baumannii ATCC 19606.Richie DL, Takeoka KT, Bojkovic J, Metzger LE 4th, Rath CM, Sawyer WS, Wei JR, Dean CRPLoS One10.1371/journal.pone.01609182016Acinetobacter baumannii/genetics/*growth & development/*metabolism, Bacterial Proteins/*metabolism, Gene Expression Regulation, Bacterial, Lipid A/*metabolism/toxicity
Genetics27563033Genome Sequence of Jumbo Phage vB_AbaM_ME3 of Acinetobacter baumanni.Buttimer C, O'Sullivan L, Elbreki M, Neve H, McAuliffe O, Ross RP, Hill C, O'Mahony J, Coffey AGenome Announc10.1128/genomeA.00431-162016
Pathogenicity27634916High-intensity meropenem combinations with polymyxin B: new strategies to overcome carbapenem resistance in Acinetobacter baumannii.Lenhard JR, Bulitta JB, Connell TD, King-Lyons N, Landersdorfer CB, Cheah SE, Thamlikitkul V, Shin BS, Rao G, Holden PN, Walsh TJ, Forrest A, Nation RL, Li J, Tsuji BTJ Antimicrob Chemother10.1093/jac/dkw3552016Acinetobacter baumannii/*drug effects, Anti-Bacterial Agents/administration & dosage/*pharmacology, Humans, Meropenem, Microbial Sensitivity Tests, Microbial Viability/drug effects, Models, Theoretical, Polymyxin B/administration & dosage/*pharmacology, Thienamycins/administration & dosage/*pharmacology, *beta-Lactam Resistance
Pathogenicity27653617Association of biofilm production with colonization among clinical isolates of Acinetobacter baumannii.Ryu SY, Baek WK, Kim HAKorean J Intern Med10.3904/kjim.2015.2872016Acinetobacter Infections/*microbiology, Acinetobacter baumannii/drug effects/*pathogenicity/physiology, Aged, Biofilms/*growth & development, Cross Infection/microbiology, Drug Resistance, Bacterial, Female, Humans, Male, Middle Aged, Republic of Korea, VirulenceBiotechnology
Pathogenicity27681618A penicillin-binding protein inhibits selection of colistin-resistant, lipooligosaccharide-deficient Acinetobacter baumannii.Boll JM, Crofts AA, Peters K, Cattoir V, Vollmer W, Davies BW, Trent MSProc Natl Acad Sci U S A10.1073/pnas.16115941132016Acinetobacter baumannii/*drug effects/genetics, Cell Membrane/metabolism, Colistin/*pharmacology, Drug Resistance, Bacterial/*drug effects, Gene Expression Regulation, Bacterial/drug effects, Genes, Bacterial, Lipopolysaccharides/biosynthesis/*deficiency, Microbial Sensitivity Tests, Penicillin-Binding Proteins/*metabolism, Sequence Analysis, RNA, Transcription, Genetic/drug effectsMetabolism
Enzymology27875572Iron-Regulated Phospholipase C Activity Contributes to the Cytolytic Activity and Virulence of Acinetobacter baumannii.Fiester SE, Arivett BA, Schmidt RE, Beckett AC, Ticak T, Carrier MV, Ghosh R, Ohneck EJ, Metz ML, Sellin Jeffries MK, Actis LAPLoS One10.1371/journal.pone.01670682016A549 Cells, Acinetobacter Infections/*enzymology/genetics, Acinetobacter baumannii/*enzymology/genetics/*pathogenicity, Animals, Bacterial Proteins/genetics/*metabolism, Cattle, Disease Models, Animal, *Genome, Bacterial, Horses, Humans, Sheep, Type C Phospholipases/genetics/*metabolismMetabolism
Metabolism27902395Virulence characteristics of Acinetobacter baumannii clinical isolates vary with the expression levels of omps.Sato Y, Unno Y, Kawakami S, Ubagai T, Ono YJ Med Microbiol10.1099/jmm.0.0003942017A549 Cells, Acinetobacter baumannii/genetics/isolation & purification/*pathogenicity, Bacterial Adhesion, Bacterial Outer Membrane Proteins/genetics/*metabolism, Coculture Techniques, Cross Infection/genetics/microbiology, Humans, Interleukin-6/metabolism, Interleukin-8/metabolism, Porins/genetics/*metabolism, RNA, Messenger/genetics/metabolism, Tumor Necrosis Factor-alpha/metabolism, Virulence Factors/genetics/*metabolismPathogenicity
Pathogenicity28167347Synergy against extensively drug-resistant Acinetobacter baumannii in vitro by two old antibiotics: colistin and chloramphenicol.Wei WJ, Yang HFInt J Antimicrob Agents10.1016/j.ijantimicag.2016.11.0312017Acinetobacter Infections/microbiology, Acinetobacter baumannii/*drug effects/isolation & purification, Anti-Bacterial Agents/*pharmacology, Chloramphenicol/*pharmacology, Colistin/*pharmacology, *Drug Resistance, Multiple, Bacterial, *Drug Synergism, Humans, Microbial Sensitivity Tests, Microbial Viability/drug effectsEnzymology
Enzymology28199190Filamentous hemagglutinin adhesin FhaB limits A.baumannii biofilm formation.Darwish Alipour Astaneh S, Rasooli I, Mousavi Gargari SLFront Biosci (Elite Ed)10.2741/e8012017Acinetobacter baumannii/genetics/*pathogenicity/physiology, Adhesins, Bacterial/chemistry/genetics/*physiology, Amino Acid Sequence, Bacterial Adhesion/genetics, Biofilms, Cloning, Molecular, Computational Biology, Conserved Sequence, Escherichia coli/genetics, Gene Expression Regulation, Bacterial, Hydrophobic and Hydrophilic Interactions, Recombinant Fusion Proteins, Sequence Alignment
28210466Antimicrobial effects of Ferula gummosa Boiss gum against extended-spectrum beta-lactamase producing Acinetobacter clinical isolates.Afshar FF, Saffarian P, Hosseini HM, Sattarian F, Amin M, Fooladi AAIran J Microbiol2016
Enzymology28505330Acinetobacter baumannii transfers the blaNDM-1 gene via outer membrane vesicles.Chatterjee S, Mondal A, Mitra S, Basu SJ Antimicrob Chemother10.1093/jac/dkx1312017Acinetobacter Infections/microbiology, Acinetobacter baumannii/drug effects/*enzymology/*genetics/isolation & purification, Biological Transport, DNA, Bacterial/isolation & purification/*metabolism, Electrophoresis, Gel, Pulsed-Field, Escherichia coli/drug effects/genetics, Exosomes/*metabolism, Gene Transfer, Horizontal, Humans, Infant, Newborn, Microbial Sensitivity Tests, Plasmids/isolation & purification, Polymerase Chain Reaction, Transformation, Bacterial, beta-Lactamases/*geneticsPathogenicity
Pathogenicity28592862Identification of unique cardiolipin and monolysocardiolipin species in Acinetobacter baumannii.Lopalco P, Stahl J, Annese C, Averhoff B, Corcelli ASci Rep10.1038/s41598-017-03214-w2017Acinetobacter baumannii/*chemistry/metabolism, Cardiolipins/*analysis/chemistry, Fatty Acids/analysis, Gas Chromatography-Mass Spectrometry, Humans, Lipids/analysis, Lysophospholipids/*analysis/chemistry, Spectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationMetabolism
Pathogenicity28623298Constraint-based modeling identifies new putative targets to fight colistin-resistant A. baumannii infections.Presta L, Bosi E, Mansouri L, Dijkshoorn L, Fani R, Fondi MSci Rep10.1038/s41598-017-03416-22017Acinetobacter Infections/drug therapy/*microbiology, Acinetobacter baumannii/*drug effects/genetics, Anti-Bacterial Agents/*pharmacology, Colistin/*pharmacology, *Drug Resistance, Bacterial, Genome, Bacterial, Genomics/methods, Humans, Microbial Sensitivity Tests, PhenotypeGenetics
Phylogeny28664218Identification of Acinetobacter baumannii of Human and Animal Origins by a Gene-Specific PCR.Hamouda ACurr Microbiol10.1007/s00284-017-1283-12017Acinetobacter Infections/*diagnosis/*veterinary, Acinetobacter baumannii/*classification/genetics/*isolation & purification, Animals, Bacteriological Techniques/*methods, Genes, Bacterial, Humans, Molecular Diagnostic Techniques/*methods, Polymerase Chain Reaction/*methods, Sensitivity and SpecificityPathogenicity
Pathogenicity28674047Subinhibitory Concentrations of Trimethoprim and Sulfamethoxazole Prevent Biofilm Formation by Acinetobacter baumannii through Inhibition of Csu Pilus Expression.Moon KH, Weber BS, Feldman MFAntimicrob Agents Chemother10.1128/AAC.00778-172017Acinetobacter Infections/*drug therapy/metabolism, Acinetobacter baumannii/*drug effects/metabolism, Anti-Bacterial Agents/pharmacology, Bacterial Proteins/*metabolism, Biofilms/*drug effects, Drug Resistance, Multiple, Bacterial/drug effects, Humans, Sulfamethoxazole/*pharmacology, Trimethoprim/*pharmacology, Virulence Factors/metabolismMetabolism
Enzymology28682615Phytochemical Studies on Two Australian Anigozanthos Plant Species.Hendra R, Keller PAJ Nat Prod10.1021/acs.jnatprod.7b000632017Acinetobacter baumannii/drug effects, Anthocyanins/chemistry/pharmacology, Anti-Bacterial Agents/chemistry/*isolation & purification/pharmacology, Australia, Chromatography, High Pressure Liquid, Dose-Response Relationship, Drug, Flavonoids/chemistry/*isolation & purification/pharmacology, Flowers/chemistry, Glycosides/chemistry/isolation & purification/pharmacology, Magnoliopsida/*chemistry, Microbial Sensitivity Tests, Molecular Structure, Nuclear Magnetic Resonance, Biomolecular, Phytochemicals/chemistry/isolation & purificationPhylogeny
Pathogenicity28781060Antibacterial activity of exogenous glutathione and its synergism on antibiotics sensitize carbapenem-associated multidrug resistant clinical isolates of Acinetobacter baumannii.Alharbe R, Almansour A, Kwon DHInt J Med Microbiol10.1016/j.ijmm.2017.07.0092017Acinetobacter baumannii/*drug effects, Anti-Bacterial Agents/*pharmacology, Bacterial Proteins/metabolism, Carbapenems/*pharmacology, Drug Resistance, Multiple, Bacterial/*drug effects, Drug Synergism, Glutathione/*pharmacology, Humans, Microbial Sensitivity Tests, beta-Lactamases/metabolismMetabolism
28815210LpxK Is Essential for Growth of Acinetobacter baumannii ATCC 19606: Relationship to Toxic Accumulation of Lipid A Pathway Intermediates.Wei JR, Richie DL, Mostafavi M, Metzger LE 4th, Rath CM, Sawyer WS, Takeoka KT, Dean CRmSphere10.1128/mSphere.00199-172017
Metabolism28947651The Capsular Polysaccharide of Acinetobacter baumannii Is an Obstacle for Therapeutic Passive Immunization Strategies.Wang-Lin SX, Olson R, Beanan JM, MacDonald U, Balthasar JP, Russo TAInfect Immun10.1128/IAI.00591-172017Acinetobacter Infections/*therapy, Acinetobacter baumannii/*immunology/metabolism, Animals, Antibodies, Bacterial/immunology/*therapeutic use, Antibodies, Monoclonal/immunology/*therapeutic use, Bacterial Outer Membrane Proteins/*immunology, Blood Bactericidal Activity, Complement System Proteins/metabolism, Disease Models, Animal, Humans, *Immunization, Passive, Mice, Polysaccharides, Bacterial/*metabolism, Protein Binding, Sepsis/therapy, Treatment OutcomePathogenicity
Transcriptome28988868Characterization of the DNA mismatch repair proteins MutS and MutL in a hypermutator Acinetobacter baumannii.Deihim B, Hassanzadeh M, Shafiei-Jandaghi NZ, Amanlou M, Douraghi MMicrob Pathog10.1016/j.micpath.2017.10.0012017Acinetobacter baumannii/*genetics/metabolism, Amino Acid Sequence/genetics, Base Sequence, DNA Mismatch Repair/*genetics, Models, Molecular, MutL Proteins/*genetics, MutS DNA Mismatch-Binding Protein/*genetics, Mutation/*genetics, Mutation Rate, Protein Structure, Secondary, Protein Structure, Tertiary, Sequence Analysis, DNAMetabolism
Pathogenicity29098912In vitro antimicrobial effects of a novel Pentaherbs concoction for atopic dermatitis.Hon KL, Ip M, Wong CK, Chan BCL, Leung PC, Leung TFJ Dermatolog Treat10.1080/09546634.2017.13958042017Anti-Infective Agents/*pharmacology/therapeutic use, Dermatitis, Atopic/drug therapy/pathology, Drugs, Chinese Herbal/*pharmacology/therapeutic use, Gram-Negative Bacteria/drug effects, Gram-Positive Bacteria/*drug effects, Humans, Methicillin-Resistant Staphylococcus aureus/drug effects, Microbial Sensitivity Tests, Staphylococcus aureus/drug effects
Pathogenicity29198102Antimicrobial and Antibiofilm Activity of Human Milk Oligosaccharides against Streptococcus agalactiae, Staphylococcus aureus, and Acinetobacter baumannii.Ackerman DL, Craft KM, Doster RS, Weitkamp JH, Aronoff DM, Gaddy JA, Townsend SDACS Infect Dis10.1021/acsinfecdis.7b001832017Acinetobacter baumannii/*drug effects/growth & development, Anti-Bacterial Agents/isolation & purification/*pharmacology, Biofilms/*drug effects/growth & development, Biological Products/isolation & purification/pharmacology, Female, Humans, Microbial Sensitivity Tests, Milk, Human/*chemistry, Oligosaccharides/isolation & purification/*pharmacology, Staphylococcus aureus/*drug effects/growth & development, Streptococcus agalactiae/*drug effects/growth & developmentEnzymology
Transcriptome29309434Mucin acts as a nutrient source and a signal for the differential expression of genes coding for cellular processes and virulence factors in Acinetobacter baumannii.Ohneck EJ, Arivett BA, Fiester SE, Wood CR, Metz ML, Simeone GM, Actis LAPLoS One10.1371/journal.pone.01905992018A549 Cells, Acinetobacter baumannii/genetics/growth & development/*pathogenicity, Biofilms, *Genes, Bacterial, Host-Pathogen Interactions, Humans, Microscopy, Electron, Transmission, Mucins/*metabolism, Real-Time Polymerase Chain Reaction, Reverse Transcriptase Polymerase Chain Reaction, Sequence Analysis, RNA, Transcriptome, Virulence/*geneticsPathogenicity
Pathogenicity29394284The role of the type VI secretion system vgrG gene in the virulence and antimicrobial resistance of Acinetobacter baumannii ATCC 19606.Wang J, Zhou Z, He F, Ruan Z, Jiang Y, Hua X, Yu YPLoS One10.1371/journal.pone.01922882018Acinetobacter baumannii/drug effects/*genetics/pathogenicity, Animals, Bacterial Proteins/*genetics, Biofilms, Drug Resistance, Bacterial/*genetics, Female, Genetic Complementation Test, Mice, Mice, Inbred BALB C, Microbial Sensitivity Tests, Mutation, Virulence/*genetics
Metabolism29505586A pathway-directed positive growth restoration assay to facilitate the discovery of lipid A and fatty acid biosynthesis inhibitors in Acinetobacter baumannii.Richie DL, Wang L, Chan H, De Pascale G, Six DA, Wei JR, Dean CRPLoS One10.1371/journal.pone.01938512018Acinetobacter baumannii/*metabolism, Biological Assay/methods, Cerulenin/pharmacology, Enoyl-(Acyl-Carrier-Protein) Reductase (NADH)/metabolism, Fatty Acid Synthases/metabolism, Fatty Acid Synthesis Inhibitors/*metabolism, Fatty Acids/*biosynthesis, Hydroxamic Acids/pharmacology, Lipid A/*metabolism, Threonine/analogs & derivatives/pharmacologyEnzymology
Phylogeny29515231Streptosporangium minutum sp. nov., isolated from garden soil exposed to microwave radiation.Le Roes-Hill M, Durrell K, Prins A, Meyers PRJ Antibiot (Tokyo)10.1038/s41429-018-0036-02018Actinomycetales/classification/genetics/*isolation & purification, Anti-Bacterial Agents/isolation & purification/pharmacology, DNA, Fungal/analysis, Databases, Genetic, Genotype, Microbial Sensitivity Tests, Microwaves, Sequence Analysis, DNA, Soil, *Soil MicrobiologyEnzymology
Pathogenicity29554105Sub-minimum inhibitory concentrations of colistin and polymyxin B promote Acinetobacter baumannii biofilm formation.Sato Y, Unno Y, Ubagai T, Ono YPLoS One10.1371/journal.pone.01945562018Acinetobacter Infections/*drug therapy/microbiology, Acinetobacter baumannii/drug effects/*physiology, Anti-Bacterial Agents/*pharmacology, Bacterial Outer Membrane Proteins/genetics/metabolism, Bacterial Proteins/genetics/metabolism, Biofilms/*drug effects, Colistin/pharmacology, Cross Infection/*drug therapy/microbiology, Dose-Response Relationship, Drug, Drug Resistance, Multiple, Bacterial, Gene Expression Regulation, Bacterial/drug effects, Humans, Membrane Transport Proteins/genetics/metabolism, Microbial Sensitivity Tests, Polymyxin B/pharmacology, RNA, Messenger/metabolismMetabolism
Metabolism29575790Salt induction and activation of MtlD, the key enzyme in the synthesis of the compatible solute mannitol in Acinetobacter baumannii.Zeidler S, Hubloher J, Konig P, Ngu ND, Scholz A, Averhoff B, Muller VMicrobiologyopen10.1002/mbo3.6142018Acinetobacter baumannii/*enzymology/genetics/growth & development/metabolism, Bacterial Proteins/genetics/*metabolism, Enzyme Activation, Gene Expression Regulation, Bacterial, Gene Expression Regulation, Enzymologic, Mannitol/*metabolism, Sodium Chloride/*metabolism, Sugar Alcohol Dehydrogenases/genetics/*metabolismEnzymology
Metabolism29638177Phenotypic changes associated with Colistin resistance due to Lipopolysaccharide loss in Acinetobacter baumannii.Carretero-Ledesma M, Garcia-Quintanilla M, Martin-Pena R, Pulido MR, Pachon J, McConnell MJVirulence10.1080/21505594.2018.14601872018Acinetobacter Infections/metabolism/*microbiology, Acinetobacter baumannii/*drug effects/genetics/metabolism/pathogenicity, Animals, Anti-Bacterial Agents/*pharmacology, Bacterial Proteins/genetics/metabolism, Colistin/*pharmacology, *Drug Resistance, Bacterial, Female, Humans, Interleukin-6/metabolism, Lipopolysaccharides/*biosynthesis, Mice, Inbred C57BL, Microbial Sensitivity Tests, Phenotype, Tumor Necrosis Factor-alpha/metabolism, VirulencePathogenicity
Pathogenicity29902105Characterization and Transcriptome Analysis of Acinetobacter baumannii Persister Cells.Alkasir R, Ma Y, Liu F, Li J, Lv N, Xue Y, Hu Y, Zhu BMicrob Drug Resist10.1089/mdr.2017.03412018Acinetobacter baumannii/drug effects/*genetics/growth & development/metabolism, Anti-Bacterial Agents/pharmacology, Biotransformation, Ceftazidime/pharmacology, Citric Acid Cycle/drug effects/genetics, Cluster Analysis, Drug Resistance, Bacterial/*genetics, Electron Transport/drug effects/genetics, Gene Expression Profiling, *Gene Expression Regulation, Bacterial, High-Throughput Nucleotide Sequencing, Hydrocarbons, Aromatic/metabolism, Metabolic Networks and Pathways/drug effects/*genetics, Microbial Sensitivity Tests, Toxin-Antitoxin Systems/drug effects/genetics, *TranscriptomeTranscriptome
Pathogenicity30043322Antimicrobial Activity of Selected Antimicrobial Peptides Against Planktonic Culture and Biofilm of Acinetobacter baumannii.Jaskiewicz M, Neubauer D, Kazor K, Bartoszewska S, Kamysz WProbiotics Antimicrob Proteins10.1007/s12602-018-9444-52019Acinetobacter baumannii/*drug effects/genetics/physiology, Anti-Bacterial Agents/*pharmacology, Biofilms/*drug effects, Cell Line, Tumor, Cell Survival/drug effects, Humans, Microbial Sensitivity Tests, Peptides/*pharmacology, Plankton/*drug effects/genetics/physiology
30108723Synergism of fused bicyclic 2-aminothiazolyl compounds with polymyxin B against Klebsiella pneumoniae.Wang R, Hou S, Dong X, Chen D, Shao L, Qian L, Li Z, Xu XMedchemcomm10.1039/c7md00354d2017
Metabolism30269854Biological roles of indole-3-acetic acid in Acinetobacter baumannii.Lin HR, Shu HY, Lin GHMicrobiol Res10.1016/j.micres.2018.08.0042018A549 Cells, Acclimatization, Acinetobacter baumannii/*drug effects/*genetics/growth & development/*metabolism, Bacterial Proteins/genetics/metabolism, Biofilms/growth & development, Biosynthetic Pathways, Culture Media/chemistry, Gene Expression Profiling, Gene Expression Regulation, Bacterial/drug effects, Genes, Bacterial/*genetics, Humans, Indoleacetic Acids/*metabolism/*pharmacology, Indoles/metabolism, Molecular Sequence Annotation, Mutation, Oxidative Stress, Phaseolus/growth & development, Plant Growth Regulators/metabolism, VirulencePathogenicity
Metabolism30277310The role of compatible solutes in desiccation resistance of Acinetobacter baumannii.Zeidler S, Muller VMicrobiologyopen10.1002/mbo3.7402018Acinetobacter baumannii/*physiology, Bacteriological Techniques, Biological Factors/*metabolism, Dehydration/*prevention & control, *Microbial Viability
Metabolism30318737Identification and characterization of a carnitine transporter in Acinetobacter baumannii.Breisch J, Waclawska I, Averhoff BMicrobiologyopen10.1002/mbo3.7522018Acinetobacter baumannii/chemistry/genetics/growth & development/*metabolism, Amino Acid Sequence, Bacterial Proteins/chemistry/genetics/*metabolism, Carnitine/metabolism, GABA Plasma Membrane Transport Proteins/chemistry/genetics/*metabolism, Sequence Alignment
Pathogenicity30373804Miltefosine Reduces the Cytolytic Activity and Virulence of Acinetobacter baumannii.Fiester SE, Arivett BA, Beckett AC, Wagner BR, Ohneck EJ, Schmidt RE, Grier JT, Actis LAAntimicrob Agents Chemother10.1128/AAC.01409-182018A549 Cells, Acinetobacter Infections/*drug therapy, Acinetobacter baumannii/*drug effects/genetics/isolation & purification/*pathogenicity, Animals, Anti-Bacterial Agents/*therapeutic use, Cell Line, Drug Resistance, Multiple, Bacterial/genetics, Humans, Microbial Sensitivity Tests, Moths/microbiology, Phosphorylcholine/*analogs & derivatives/therapeutic use, Type C Phospholipases/antagonists & inhibitors, Virulence/drug effectsEnzymology
Pathogenicity30561174Isothiazolopyridine Mannich bases and their antibacterial effect.Swiatek P, Strzelecka MAdv Clin Exp Med10.17219/acem/993102019Anti-Bacterial Agents/*pharmacology, Bacteria/*drug effects, Humans, Mannich Bases/*pharmacology, Microbial Sensitivity Tests, Spectroscopy, Fourier Transform Infrared
30746493Metabolic Responses to Polymyxin Treatment in Acinetobacter baumannii ATCC 19606: Integrating Transcriptomics and Metabolomics with Genome-Scale Metabolic Modeling.Zhu Y, Zhao J, Maifiah MHM, Velkov T, Schreiber F, Li JmSystems10.1128/mSystems.00157-182019
Metabolism30783664The chloramphenicol/H+ antiporter CraA of Acinetobacter baumannii AYE reveals a broad substrate specificity.Foong WE, Tam HK, Crames JJ, Averhoff B, Pos KMJ Antimicrob Chemother10.1093/jac/dkz0242019Acinetobacter Infections/microbiology, Acinetobacter baumannii/drug effects/*genetics/*metabolism, Amino Acid Sequence, Anti-Bacterial Agents/metabolism/pharmacology, Antiporters/chemistry/*genetics/*metabolism, Bacterial Proteins/genetics/metabolism, Biological Transport, Chloramphenicol/*metabolism, Cloning, Molecular, Drug Resistance, Bacterial, Hydrogen/*metabolism, Models, Molecular, Protein Conformation, Sequence Analysis, DNA, Substrate SpecificityEnzymology
Pathogenicity30986481Analysis of Acinetobacter baumannii survival in liquid media and on solid matrices as well as effect of disinfectants.Bravo Z, Orruno M, Navascues T, Ogayar E, Ramos-Vivas J, Kaberdin VR, Arana IJ Hosp Infect10.1016/j.jhin.2019.04.0092019Acinetobacter baumannii/*drug effects/*physiology/radiation effects, Culture Media/chemistry, Disinfectants/*pharmacology, Environmental Microbiology, Microbial Viability/*drug effects/radiation effects, TemperatureCultivation
Pathogenicity31281799Delineating the Plausible Molecular Vaccine Candidates and Drug Targets of Multidrug-Resistant Acinetobacter baumannii.Mujawar S, Mishra R, Pawar S, Gatherer D, Lahiri CFront Cell Infect Microbiol10.3389/fcimb.2019.002032019Acinetobacter Infections/drug therapy/immunology/microbiology/prevention & control, Acinetobacter baumannii/*drug effects/genetics, Anti-Bacterial Agents/*pharmacology, Bacterial Proteins/genetics, Bacterial Vaccines/*therapeutic use, Computational Biology, Cross Infection, Drug Resistance, Multiple, Bacterial/*drug effects, Genome, Bacterial, Genomics, Humans, Protein Interaction Maps/drug effects/genetics, Proteomics, Vaccines, Synthetic/*pharmacology, Virulence Factors/geneticsGenetics
Pathogenicity31324623New Shuttle Vectors for Real-Time Gene Expression Analysis in Multidrug-Resistant Acinetobacter Species: In Vitro and In Vivo Responses to Environmental Stressors.Lucidi M, Visaggio D, Prencipe E, Imperi F, Rampioni G, Cincotti G, Leoni L, Visca PAppl Environ Microbiol10.1128/AEM.01334-192019Acinetobacter/drug effects/*genetics, Anti-Bacterial Agents/pharmacology, Drug Resistance, Multiple, Bacterial/*genetics, Escherichia coli/genetics, Gene Expression Profiling/*methods, Genetic Vectors/*pharmacologyStress
31456903Efficacy of Poloxamer-Based Wound Dressings on Acinetobacter baumanni Biofilms.Salisbury AM, Mullin M, Chen R, Percival SLAdv Wound Care (New Rochelle)10.1089/wound.2018.08542019
31577808Computational screening of antimicrobial peptides for Acinetobacter baumannii.Majumder A, Biswal MR, Prakash MKPLoS One10.1371/journal.pone.02196932019Acinetobacter baumannii/*growth & development, *Anti-Bacterial Agents/chemistry/pharmacology, *Antimicrobial Cationic Peptides/chemistry/pharmacology, *Computer Simulation, Drug Evaluation, Preclinical, *Models, Biological
Pathogenicity31767923Multidrug-resistant Acinetobacter baumannii resists reactive oxygen species and survives in macrophages.Sato Y, Unno Y, Miyazaki C, Ubagai T, Ono YSci Rep10.1038/s41598-019-53846-32019Acinetobacter Infections/microbiology, Acinetobacter baumannii/*drug effects/isolation & purification/metabolism/pathogenicity, Animals, Catalase/analysis, Cell Line, Colistin/pharmacology, Cytokines/biosynthesis/genetics, *Drug Resistance, Multiple, Bacterial, Humans, Hydrogen Peroxide/pharmacology, Macrophages/enzymology/*microbiology, Mice, Phagocytosis, Reactive Oxygen Species/*pharmacology, Tigecycline/pharmacology, VirulenceEnzymology
31814741Combined Effects Of Low Incubation Temperature, Minimal Growth Medium, And Low Hydrodynamics Optimize Acinetobacter baumannii Biofilm Formation.Eze EC, El Zowalaty MEInfect Drug Resist10.2147/IDR.S2039192019
Pathogenicity31837449Diversity of amino acid substitutions in PmrCAB associated with colistin resistance in clinical isolates of Acinetobacter baumannii.Gerson S, Lucassen K, Wille J, Nodari CS, Stefanik D, Nowak J, Wille T, Betts JW, Roca I, Vila J, Cisneros JM, Seifert H, Higgins PGInt J Antimicrob Agents10.1016/j.ijantimicag.2019.1058622019Acinetobacter Infections/drug therapy/*microbiology, Acinetobacter baumannii/drug effects/*genetics, Amino Acid Substitution, Anti-Bacterial Agents/*pharmacology, Bacterial Proteins/*genetics, Colistin/*pharmacology, Drug Resistance, Bacterial/genetics, Greece, Humans, Pneumonia, Ventilator-Associated/drug therapy/*microbiology
31843268A lipopolysaccharide-free outer membrane vesicle vaccine protects against Acinetobacter baumannii infection.Pulido MR, Garcia-Quintanilla M, Pachon J, McConnell MJVaccine10.1016/j.vaccine.2019.11.0432019Acinetobacter Infections/*prevention & control, Acinetobacter baumannii/*immunology, Animals, Bacterial Outer Membrane Proteins/*immunology, Bacterial Proteins/genetics, Bacterial Vaccines/*administration & dosage/immunology, Female, Immunization, Immunoglobulin G/immunology, Immunoglobulin M/immunology, Lipopolysaccharides/physiology, Mice, Mice, Inbred C57BL, Sepsis/microbiology/prevention & control, Spleen/microbiology
Pathogenicity31874074The Acinetobacter trimeric autotransporter adhesin Ata controls key virulence traits of Acinetobacter baumannii.Weidensdorfer M, Ishikawa M, Hori K, Linke D, Djahanschiri B, Iruegas R, Ebersberger I, Riedel-Christ S, Enders G, Leukert L, Kraiczy P, Rothweiler F, Cinatl J, Berger J, Hipp K, Kempf VAJ, Gottig SVirulence10.1080/21505594.2018.15586932019Acinetobacter Infections/microbiology, Acinetobacter baumannii/*genetics/*pathogenicity, Adhesins, Bacterial/*genetics, Animals, Apoptosis, Bacterial Adhesion/genetics, Cells, Cultured, Epithelial Cells/immunology/microbiology, Human Umbilical Vein Endothelial Cells/immunology/microbiology, Humans, Interleukin-6/immunology, Interleukin-8/immunology, Larva/microbiology, Moths/microbiology, Mutation, Phylogeny, Type V Secretion Systems/*genetics, Umbilical Cord/cytology, Virulence, Virulence Factors/*geneticsPhylogeny
Transcriptome32046644Integrative analysis of outer membrane vesicles proteomics and whole-cell transcriptome analysis of eravacycline induced Acinetobacter baumannii strains.Kesavan D, Vasudevan A, Wu L, Chen J, Su Z, Wang S, Xu HBMC Microbiol10.1186/s12866-020-1722-12020Acinetobacter baumannii/*drug effects/genetics/metabolism, Bacterial Outer Membrane Proteins/*genetics/*metabolism, Drug Resistance, Bacterial, Gene Expression Profiling/methods, Gene Expression Regulation, Bacterial/drug effects, Gene Regulatory Networks/drug effects, High-Throughput Nucleotide Sequencing, Microbial Sensitivity Tests, Proteomics/methods, Secretory Vesicles/genetics/metabolism, Sequence Analysis, RNA, Tetracyclines/*pharmacology, Whole Exome SequencingPathogenicity
32049277Tigecycline efflux in Acinetobacter baumannii is mediated by TetA in synergy with RND-type efflux transporters.Foong WE, Wilhelm J, Tam HK, Pos KMJ Antimicrob Chemother10.1093/jac/dkaa0152020*Acinetobacter baumannii/genetics, Anti-Bacterial Agents/pharmacology, Bacterial Proteins/genetics, Cell Division, Drug Resistance, Multiple, Bacterial/genetics, Escherichia coli/genetics, Microbial Sensitivity Tests, Tigecycline
Metabolism32079040Unusual deprivation of compatible solutes in Acinetobacter baumannii.Zeidler S, Muller VEnviron Microbiol10.1111/1462-2920.149512020Acinetobacter baumannii/*metabolism, Glutamic Acid/metabolism, Mannitol/metabolism, Osmotic Pressure
Genetics32081464Complete genome sequence and genome-scale metabolic modelling of Acinetobacter baumannii type strain ATCC 19606.Zhu Y, Lu J, Zhao J, Zhang X, Yu HH, Velkov T, Li JInt J Med Microbiol10.1016/j.ijmm.2020.1514122020Acinetobacter baumannii/drug effects/*genetics/*metabolism, Anti-Bacterial Agents/pharmacology, Bacterial Proteins/genetics/*metabolism, DNA Transposable Elements, Drug Resistance, Multiple, Bacterial/genetics, Genes, Bacterial, *Genome, Bacterial, Microbial Sensitivity Tests, Virulence Factors/genetics, Whole Genome SequencingMetabolism
Pathogenicity32152526Deciphering colistin heteroresistance in Acinetobacter baumannii clinical isolates from Wenzhou, China.Chen L, Lin J, Lu H, Zhang X, Wang C, Liu H, Zhang X, Li J, Cao J, Zhou TJ Antibiot (Tokyo)10.1038/s41429-020-0289-22020Acinetobacter Infections/*drug therapy/microbiology, Acinetobacter baumannii/*drug effects/*isolation & purification, Anti-Bacterial Agents/pharmacology, China, Colistin/*pharmacology, Drug Resistance, Multiple, Bacterial/*drug effects, Humans, Microbial Sensitivity Tests/methodsEnzymology
Pathogenicity32238571New Mutations Involved in Colistin Resistance in Acinetobacter baumannii.Sun B, Liu H, Jiang Y, Shao L, Yang S, Chen DmSphere10.1128/mSphere.00895-192020Acinetobacter Infections/microbiology, Acinetobacter baumannii/*drug effects/*genetics, Anti-Bacterial Agents/*pharmacology, Colistin/*pharmacology, Drug Resistance, Bacterial/*genetics, Microbial Sensitivity Tests, Mutation
Pathogenicity32304941Healthcare-associated carbapenem-resistant OXA-72-producing Acinetobacter baumannii of the clonal complex CC79 colonizing migratory and captive aquatic birds in a Brazilian Zoo.Narciso AC, Martins WMBS, Almeida LGP, Cayo R, Santos SV, Ramos PL, Lincopan N, Vasconcelos ATR, Gales ACSci Total Environ10.1016/j.scitotenv.2020.1382322020*Acinetobacter Infections, Acinetobacter baumannii/*drug effects, Animals, Anti-Bacterial Agents/pharmacology, Bacterial Proteins/genetics, Birds, Brazil, Carbapenems, Drug Resistance, Bacterial/drug effects, Humans, Macrolides, Microbial Sensitivity Tests, Multilocus Sequence Typing, beta-Lactamases
Phylogeny32365048Decreased carO gene expression and OXA-type carbapenemases among extensively drug-resistant Acinetobacter baumannii strains isolated from burn patients in Tehran, Iran.Abbasi E, Goudarzi H, Hashemi A, Chirani AS, Ardebili A, Goudarzi M, Sharahi JY, Davoudabadi S, Talebi G, Bostanghadiri NActa Microbiol Immunol Hung10.1556/030.2020.011382020Pathogenicity
Genetics32409539Complete Genome Sequence of Acinetobacter baumannii ATCC 19606(T), a Model Strain of Pathogenic Bacteria Causing Nosocomial Infection.Tsubouchi T, Suzuki M, Niki M, Oinuma KI, Niki M, Kakeya H, Kaneko YMicrobiol Resour Announc10.1128/MRA.00289-202020
Pathogenicity32445596Prevention of nosocomial Acinetobacter baumannii infections with a conserved immunogenic fimbrial protein.Mahmoudi Z, Rasooli I, Jahangiri A, Darvish Alipour Astaneh SAPMIS10.1111/apm.130612020A549 Cells, Acinetobacter Infections/*prevention & control, Acinetobacter baumannii/*immunology, Animals, Bacterial Adhesion, Bacterial Outer Membrane Proteins/*immunology, Bacterial Vaccines/*immunology, Cross Infection/*prevention & control, Fimbriae, Bacterial/*immunology, Humans, *Immunization, Mice, Mice, Inbred BALB C
Pathogenicity32469363Pan-transcriptomic analysis identified common differentially expressed genes of Acinetobacter baumannii in response to polymyxin treatments.Li M, Aye SM, Ahmed MU, Han ML, Li C, Song J, Boyce JD, Powell DR, Azad MAK, Velkov T, Zhu Y, Li JMol Omics10.1039/d0mo00015a2020Acinetobacter Infections/drug therapy/microbiology, Acinetobacter baumannii/*drug effects/*genetics, Anti-Bacterial Agents/*pharmacology/therapeutic use, Computational Biology/methods, Databases, Genetic, *Gene Expression Profiling, Gene Expression Regulation, Bacterial/*drug effects, Gene Expression Regulation, Enzymologic, Genomics/methods, Humans, Phylogeny, Polymyxins/*pharmacology/therapeutic use, Time Factors, *TranscriptomePhylogeny
Metabolism32618111Trehalose-6-phosphate-mediated phenotypic change in Acinetobacter baumannii.Hubloher JJ, Zeidler S, Lamosa P, Santos H, Averhoff B, Muller VEnviron Microbiol10.1111/1462-2920.151482020Acinetobacter baumannii/genetics/growth & development/metabolism/*physiology, Bacterial Proteins/genetics/metabolism, Glucosyltransferases/genetics/metabolism, Hot Temperature, Phenotype, Phosphoric Monoester Hydrolases/genetics/metabolism, Sodium Chloride/metabolism, Sugar Phosphates/*metabolism, Trehalose/*analogs & derivatives/metabolismStress
Phylogeny32928115Characterization of carbapenem-resistant hypervirulent Acinetobacter baumannii strains isolated from hospitalized patients in the mid-south region of China.Li J, Yu T, Luo Y, Peng JY, Li YJ, Tao XY, Hu YM, Wang HC, Zou MXBMC Microbiol10.1186/s12866-020-01957-72020Acinetobacter Infections/drug therapy/etiology/*microbiology, Acinetobacter baumannii/*drug effects/*genetics/isolation & purification/*pathogenicity, Adolescent, Adult, Aged, Animals, Anti-Bacterial Agents/pharmacology, Biofilms, Carbapenems/*pharmacology, Child, China, Disease Models, Animal, Drug Resistance, Bacterial/genetics, Humans, Microbial Sensitivity Tests, Middle Aged, Moths/microbiology, Phylogeny, Virulence/genetics, Young AdultPathogenicity
Metabolism32929857In vivo synthesis of monolysocardiolipin and cardiolipin by Acinetobacter baumannii phospholipase D and effect on cationic antimicrobial peptide resistance.Pfefferle K, Lopalco P, Breisch J, Siemund A, Corcelli A, Averhoff BEnviron Microbiol10.1111/1462-2920.152312020Acinetobacter baumannii/drug effects/genetics/*metabolism, Anti-Bacterial Agents/pharmacology, Antimicrobial Cationic Peptides/*metabolism/pharmacology, Bacterial Proteins/genetics/metabolism, Cardiolipins/*biosynthesis, *Drug Resistance, Bacterial, Lysophospholipids/biosynthesis, Mutation, Phospholipase D/genetics/*metabolism, Virulence Factors/genetics/metabolismPathogenicity
Genetics33255319Analysis of Complete Genome Sequence of Acinetobacter baumannii Strain ATCC 19606 Reveals Novel Mobile Genetic Elements and Novel Prophage.Hamidian M, Blasco L, Tillman LN, To J, Tomas M, Myers GSAMicroorganisms10.3390/microorganisms81218512020
Metabolism33329595Analysis of Immune Responses in Acinetobacter baumannii-Infected Klotho Knockout Mice: A Mouse Model of Acinetobacter baumannii Infection in Aged Hosts.Sato Y, Tansho-Nagakawa S, Ubagai T, Ono YFront Immunol10.3389/fimmu.2020.6016142020Acinetobacter Infections/genetics/*immunology/metabolism/microbiology, Acinetobacter baumannii/*immunology/pathogenicity, Age Factors, Animals, Bacterial Load, Cytokines/genetics/*metabolism, Disease Models, Animal, Glucuronidase/*deficiency/genetics, Host-Parasite Interactions, Klotho Proteins, Lung/*immunology/metabolism/microbiology, Male, Mice, Knockout, Pneumonia, Bacterial/genetics/*immunology/metabolism/microbiology, Toll-Like Receptor 9/genetics/metabolismPathogenicity
Pathogenicity33456052A small molecule interacts with pMAC-derived hydroperoxide reductase and enhances the activity of aminoglycosides.Hui Z, Liu S, Cui R, Zhou B, Hu C, Zhang M, Deng Q, Cheng S, Luo Y, Chen H, Wu J, Lu Y, Liu X, Dai L, Huang WJ Antibiot (Tokyo)10.1038/s41429-020-00401-22021Acinetobacter baumannii/*drug effects, Aminoglycosides/administration & dosage/*pharmacology, Anti-Bacterial Agents/*pharmacology, Drug Resistance, Multiple, Bacterial, Drug Synergism, Gene Expression Regulation, Bacterial, Genome, Bacterial, Klebsiella pneumoniae/*drug effects, Microbial Sensitivity Tests, Peroxiredoxins/*metabolism, Pseudomonas aeruginosa/*drug effects, Whole Genome SequencingGenetics
Pathogenicity33544031The Low-Alkalinity Polymyxin Derivative, AL-6, Shows High Activity Against Multidrug-Resistant Acinetobacter baumannii Clinical Isolates In Vitro and A. baumannii ATCC 19606 In Vivo: Preliminary Analysis of the Antibacterial Mechanism.Chen DJ, Cui AL, Chen JR, Yang P, Jin J, Shao L, Li ZRMicrob Drug Resist10.1089/mdr.2019.04742021Acinetobacter baumannii/*drug effects, Animals, Anti-Bacterial Agents/administration & dosage/adverse effects/*pharmacology, Dose-Response Relationship, Drug, Drug Resistance, Multiple, Bacterial/*drug effects, Drug Synergism, Mice, Microbial Sensitivity Tests, Polymyxins/administration & dosage/adverse effects/*pharmacology
Phylogeny33591460Acinetobacter stercoris sp. nov. isolated from output source of a mesophilic german biogas plant with anaerobic operating conditions.Pulami D, Schauss T, Eisenberg T, Blom J, Schwengers O, Bender JK, Wilharm G, Kampfer P, Glaeser SPAntonie Van Leeuwenhoek10.1007/s10482-021-01517-72021*Acinetobacter/genetics, Anaerobiosis, Bacterial Typing Techniques, Base Composition, *Biofuels, DNA, Bacterial/genetics, Fatty Acids/analysis, Nucleic Acid Hybridization, Phylogeny, RNA, Ribosomal, 16S/genetics, Sequence Analysis, DNATranscriptome
Pathogenicity33612816Time-kill and post-antibiotic effect of colistin at different static concentrations in in vitro Acinetobacter baumannii.Rasidin RSM, Suhaili Z, Mohamed AFS, Hod R, Neela V, Amin-Nordin STrop Biomed2020Acinetobacter baumannii/*drug effects, Anti-Bacterial Agents/*pharmacology, Colistin/*pharmacology, Drug Resistance, Bacterial, *Microbial Sensitivity Tests
Pathogenicity33657146AB569, a non-toxic combination of acidified nitrite and EDTA, is effective at killing the notorious Iraq/Afghanistan combat wound pathogens, multi-drug resistant Acinetobacter baumannii and Acinetobacter spp.Bogue AL, Panmanee W, McDaniel CT, Mortensen JE, Kamau E, Actis LA, Johannigman JA, Schurr MJ, Satish L, Kotagiri N, Hassett DJPLoS One10.1371/journal.pone.02475132021Acinetobacter Infections/epidemiology/*microbiology, Acinetobacter baumannii/*drug effects/genetics, Adult, *Afghan Campaign 2001-, Afghanistan/epidemiology, Anti-Bacterial Agents/chemistry/*pharmacology, Biofilms/drug effects, Cells, Cultured, Disinfectants/chemistry/*pharmacology, Drug Combinations, Drug Resistance, Multiple, Bacterial/*drug effects/genetics, Edetic Acid/chemistry/*pharmacology, Fibroblasts/drug effects/metabolism, Gene Expression/drug effects, Humans, Iraq/epidemiology, *Iraq War, 2003-2011, Microbial Sensitivity Tests, Nitrites/chemistry/*pharmacology, Polymerase Chain Reaction, Skin/cytology, Wound Infection/epidemiology/*microbiologyMetabolism
Pathogenicity33675719Investigation of antibiofilm activity, antibacterial activity, and mechanistic studies of an amphiphilic peptide against Acinetobacter baumannii.Zeng P, Yi L, Xu J, Gao W, Xu C, Chen S, Chan KF, Wong KYBiochim Biophys Acta Biomembr10.1016/j.bbamem.2021.1836002021Acinetobacter baumannii/drug effects/*physiology, Animals, Anti-Bacterial Agents/chemistry/metabolism/*pharmacology, Biofilms/*drug effects, Cell Survival/drug effects, Chlorocebus aethiops, Larva/drug effects/microbiology, Membrane Potentials/drug effects, Microbial Sensitivity Tests, Moths/growth & development, Peptides/*chemistry/metabolism/pharmacology, Vero CellsMetabolism
Pathogenicity33802578Acinetobacter baumannii LOS Regulate the Expression of Inflammatory Cytokine Genes and Proteins in Human Mast Cells.Kikuchi-Ueda T, Ubagai T, Kamoshida G, Nakano R, Nakano A, Ono YPathogens10.3390/pathogens100302902021
33803549Regulation of tert-Butyl Hydroperoxide Resistance by Chromosomal OhrR in A. baumannii ATCC 19606.Chen SJ, Shu HY, Lin GHMicroorganisms10.3390/microorganisms90306292021
Pathogenicity33906516PHMB-loaded PDMS and its antimicrobial properties for biomedical applications.Montemezzo M, Ferrari MD, Kerstner E, Santos VD, Victorazzi Lain V, Wollheim C, Frozza CODS, Roesch-Ely M, Baldo G, Brandalise RNJ Biomater Appl10.1177/088532822110119212021Animals, Anti-Infective Agents/*chemistry/metabolism/pharmacology, Biocompatible Materials/chemistry/pharmacology, Biofilms/drug effects, Candida albicans/drug effects/physiology, Cell Line, Cell Survival/drug effects, Dimethylpolysiloxanes/*chemistry, Escherichia coli/drug effects/physiology, Guanidines/*chemistry/metabolism/pharmacology, Humans, Mice, Microbial Sensitivity Tests, Staphylococcus aureus/drug effects/physiologyMetabolism
Genetics33912474Two Acinetobacter baumannii Isolates Obtained From a Fatal Necrotizing Fasciitis Infection Display Distinct Genomic and Phenotypic Characteristics in Comparison to Type Strains.Grier JT, Arivett BA, Ramirez MS, Chosed RJ, Bigner JA, Ohneck EJ, Metz ML, Wood CR, Arce S, Tartaro A, Relich RF, Actis LA, Fiester SEFront Cell Infect Microbiol10.3389/fcimb.2021.6356732021*Acinetobacter Infections, *Acinetobacter baumannii, Anti-Bacterial Agents, Biofilms, *Fasciitis, Necrotizing, Genomics, Humans, PhenotypePathogenicity
Metabolism34097477Comparison of the Acinetobacter baumannii Reference Strains ATCC 17978 and ATCC 19606 in Antimicrobial Resistance Mediated by the AdeABC Efflux Pump.Lucassen K, Gerson S, Xanthopoulou K, Wille J, Wille T, Seifert H, Higgins PGAntimicrob Agents Chemother10.1128/AAC.00570-212021*Acinetobacter baumannii/genetics/metabolism, Anti-Bacterial Agents/pharmacology, Bacterial Proteins/genetics/metabolism, Drug Resistance, Bacterial/genetics, Drug Resistance, Multiple, Bacterial/genetics, Membrane Transport Proteins/genetics, Microbial Sensitivity Tests
Pathogenicity34144496K(+) and its role in virulence of Acinetobacter baumannii.Konig P, Averhoff B, Muller VInt J Med Microbiol10.1016/j.ijmm.2021.1515162021*Acinetobacter baumannii/genetics, Amino Acids, Animals, Humans, *Moths, Phenotype, VirulencePhenotype
Pathogenicity34252992Novel Phenyl-Based Bis-quaternary Ammonium Compounds as Broad-Spectrum Biocides.Frolov NA, Fedoseeva KA, Hansford KA, Vereshchagin ANChemMedChem10.1002/cmdc.2021002842021Acinetobacter baumannii/drug effects, Anti-Bacterial Agents/chemical synthesis/chemistry/*pharmacology, Antifungal Agents/chemical synthesis/chemistry/*pharmacology, Candida albicans/drug effects, Cryptococcus neoformans/drug effects, Disinfectants/chemical synthesis/chemistry/*pharmacology, Dose-Response Relationship, Drug, Escherichia coli/drug effects, Klebsiella pneumoniae/drug effects, Methicillin-Resistant Staphylococcus aureus/drug effects, Microbial Sensitivity Tests, Molecular Structure, Pseudomonas aeruginosa/drug effects, Quaternary Ammonium Compounds/chemical synthesis/chemistry/*pharmacology, Structure-Activity Relationship
34265885Antibiofilm action of Persea americana glycolic extract over Acinetobacter baumannii and absence of toxicity in Galleria mellonella.Dos Santos Liberato SF, da Cruz Vegian MR, Abu Hasna A, de Alvarenga JA, Dos Santos JG, Tini IRP, Amendola I, Junqueira JC, de Oliveira LDJ Complement Integr Med10.1515/jcim-2021-00512021
Metabolism34370792Modern Acinetobacter baumannii clinical isolates replicate inside spacious vacuoles and egress from macrophages.Sycz G, Di Venanzio G, Distel JS, Sartorio MG, Le NH, Scott NE, Beatty WL, Feldman MFPLoS Pathog10.1371/journal.ppat.10098022021Acinetobacter Infections/metabolism/*microbiology, Acinetobacter baumannii/*physiology, Animals, Bacterial Proteins/*metabolism, Biofilms/*growth & development, Macrophages/*microbiology, Mice, Type I Secretion Systems/*metabolism, Vacuoles/*microbiology
Phylogeny34426860Description of Lujinxingia vulgaris sp. nov., isolated from coastal sediment via prey-traps.Wang S, Mu DS, Li GY, Du ZJAntonie Van Leeuwenhoek10.1007/s10482-021-01640-52021Bacillaceae, Bacterial Typing Techniques, Bacteroidetes, China, DNA, Bacterial/genetics, Fatty Acids/analysis, *Geologic Sediments, Phospholipids, Phylogeny, RNA, Ribosomal, 16S/genetics, *Seawater, Sequence Analysis, DNATranscriptome
Pathogenicity34544274Synergism versus Additivity: Defining the Interactions between Common Disinfectants.Noel DJ, Keevil CW, Wilks SAmBio10.1128/mBio.02281-212021Acinetobacter baumannii/drug effects/growth & development, Benzalkonium Compounds/*pharmacology, Biguanides/*pharmacology, Cresols/*pharmacology, Disinfectants/*pharmacology, Drug Synergism, Enterococcus faecalis/drug effects/growth & development, Klebsiella pneumoniae/drug effects/growth & development, Microbial Sensitivity Tests, Propylene Glycols/*pharmacology, Quaternary Ammonium Compounds/*pharmacokinetics/pharmacology, Staphylococcus aureus/drug effects/growth & developmentEnzymology
Metabolism34576087Role of Iron-Containing Alcohol Dehydrogenases in Acinetobacter baumannii ATCC 19606 Stress Resistance and Virulence.Lin GH, Hsieh MC, Shu HYInt J Mol Sci10.3390/ijms221899212021Acinetobacter baumannii/*enzymology/genetics/*pathogenicity/physiology, Alcohol Dehydrogenase/chemistry/genetics/*metabolism, Amino Acid Sequence, Animals, Computer Simulation, Cytosol/metabolism, Ethanol/pharmacology, Gene Expression Regulation, Bacterial/drug effects, Genes, Bacterial, Homeostasis/drug effects, Hydrogen-Ion Concentration, Iron/*metabolism, Melanins/metabolism, Moths/microbiology, Mutation/genetics, Oxidative Stress/drug effects, Phylogeny, *Stress, Physiological, VirulenceEnzymology
Proteome34621692Strategies for Rapid Identification of Acinetobacter baumannii Membrane Proteins and Polymyxin B's Effects.Lu Y, Hu X, Nie T, Yang X, Li C, You XFront Cell Infect Microbiol10.3389/fcimb.2021.7345782021*Acinetobacter baumannii, Anti-Bacterial Agents/pharmacology, Membrane Proteins, Microbial Sensitivity Tests, Polymyxin B/pharmacology, Polymyxins, Tandem Mass Spectrometry
34680840Effect of Subinhibitory Concentrations of Antibiotics and Disinfectants on ISAba-Mediated Inactivation of Lipooligosaccharide Biosynthesis Genes in Acinetobacter baumannii.Olmeda-Lopez H, Corral-Lugo A, McConnell MJAntibiotics (Basel)10.3390/antibiotics101012592021
34712048Combination of AgNPs and Domiphen is Antimicrobial Against Biofilms of Common Pathogens.Hu L, Yang X, Yin J, Rong X, Huang X, Yu P, He Z, Liu YInt J Nanomedicine10.2147/IJN.S3341332021Anti-Bacterial Agents/pharmacology, *Anti-Infective Agents/pharmacology, Biofilms, *Metal Nanoparticles, Microbial Sensitivity Tests, Plant Extracts/pharmacology, Quaternary Ammonium Compounds, Silver/pharmacology
Metabolism34730379CsrA Coordinates Compatible Solute Synthesis in Acinetobacter baumannii and Facilitates Growth in Human Urine.Hubloher JJ, Schabacker K, Muller V, Averhoff BMicrobiol Spectr10.1128/Spectrum.01296-212021Acinetobacter baumannii/genetics/*growth & development, Adaptation, Physiological/*genetics, Bacterial Proteins/*genetics/metabolism, Gene Deletion, Humans, Osmotic Pressure/*physiology, Repressor Proteins/genetics/metabolism, Transcription Factors/genetics/metabolism, Urine/*microbiologyPathogenicity
Pathogenicity34763140Integrating transcriptomics and metabolomics analysis on kojic acid combating Acinetobacter baumannii biofilm and its potential roles.Li H, Du X, Chen C, Qi J, Wang YMicrobiol Res10.1016/j.micres.2021.1269112021*Acinetobacter baumannii/drug effects/genetics, *Biofilms/drug effects, *Metabolome/drug effects, Metabolomics, *Pyrones/pharmacology, *Transcriptome/drug effectsTranscriptome
34798280Anti-Omp34 antibodies protect against Acinetobacter baumannii in a murine sepsis model.Naghipour Erami A, Rasooli I, Jahangiri A, Darvish Alipour Astaneh SMicrob Pathog10.1016/j.micpath.2021.1052912021*Acinetobacter Infections/prevention & control, *Acinetobacter baumannii, Animals, Bacterial Outer Membrane Proteins, Bacterial Vaccines, Escherichia coli, Mice, *Sepsis/prevention & control
34925284Subinhibitory Concentrations of Clinically-Relevant Antimicrobials Affect Resistance-Nodulation-Division Family Promoter Activity in Acinetobacter baumannii.Prieto Martin Gil S, Tajuelo A, Lopez-Siles M, McConnell MJFront Microbiol10.3389/fmicb.2021.7802012021
35003278Histopathological Analysis of Acinetobacter baumannii Lung Infection in a Mouse Model.Tansho-Nagakawa S, Sato Y, Ubagai T, Kikuchi-Ueda T, Kamoshida GO, Nishida S, Ono YPol J Microbiol10.33073/pjm-2021-0442021*Acinetobacter Infections, *Acinetobacter baumannii, Animals, Lung/microbiology, Mice, Mice, Inbred C3H, *Pneumonia
Pathogenicity35026999Antimicrobial and anti-biofilm potencies of dermcidin-derived peptide DCD-1L against Acinetobacter baumannii: an in vivo wound healing model.Farshadzadeh Z, Pourhajibagher M, Taheri B, Ekrami A, Modarressi MH, Azimzadeh M, Bahador ABMC Microbiol10.1186/s12866-022-02439-82022Acinetobacter Infections/complications/*drug therapy, Acinetobacter baumannii/*drug effects, Animals, Anti-Bacterial Agents/*pharmacology, Biofilms/*drug effects, Disease Models, Animal, Drug Resistance, Multiple, Bacterial, Female, Humans, Mice, Mice, Inbred BALB C, Microbial Sensitivity Tests, Peptides/*pharmacology, Wound Healing/*drug effects, Wound Infection/drug therapy/microbiology
Phylogeny35084299Genome diversity of domesticated Acinetobacter baumannii ATCC 19606(T) strains.Artuso I, Lucidi M, Visaggio D, Capecchi G, Lugli GA, Ventura M, Visca PMicrob Genom10.1099/mgen.0.0007492022Acinetobacter baumannii/*classification/genetics/isolation & purification/virology, Cross Infection/*microbiology, Evolution, Molecular, *Genetic Variation, Genome, Bacterial, High-Throughput Nucleotide Sequencing, Humans, Intensive Care Units, Plasmids/genetics, Polymorphism, Single Nucleotide, Prophages/genetics/isolation & purification, Sequence Deletion, Whole Genome Sequencing/*methodsGenetics
35097270Ciprofloxacin-Tethered 1,2,3-Triazole Conjugates: New Quinolone Family Compounds to Upgrade Our Antiquated Approach against Bacterial Infections.Agarwal A, Singh P, Maurya A, Patel UK, Singh A, Nath GACS Omega10.1021/acsomega.1c053032022
35155494The Involvement of the csy1 Gene in the Antimicrobial Resistance of Acinetobacter baumannii.Guo T, Sun X, Li M, Wang Y, Jiao H, Li GFront Med (Lausanne)10.3389/fmed.2022.7971042022
35197939Inhibition of AdeB, AceI, and AmvA Efflux Pumps Restores Chlorhexidine and Benzalkonium Susceptibility in Acinetobacter baumannii ATCC 19606.Migliaccio A, Esposito EP, Bagattini M, Berisio R, Triassi M, De Gregorio E, Zarrilli RFront Microbiol10.3389/fmicb.2021.7902632022
35254548Immunity induced by valine-glycine repeat protein G imparts histoprotection of vital body organs against Acinetobacter baumannii.Alipouri S, Rasooli I, Ghaini MH, Jahangiri A, Darvish Alipour Astaneh S, Ramezanalizadeh FJ Genet Eng Biotechnol10.1186/s43141-022-00325-42022
35456620Mechanisms Underlying Synergistic Killing of Polymyxin B in Combination with Cannabidiol against Acinetobacter baumannii: A Metabolomic Study.Hussein M, Allobawi R, Levou I, Blaskovich MAT, Rao GG, Li J, Velkov TPharmaceutics10.3390/pharmaceutics140407862022
35503000Ketoprofen, piroxicam and indomethacin-suppressed quorum sensing and virulence factors in Acinetobacter baumannii.Elshaer SL, Shaldam MA, Shaaban MIJ Appl Microbiol10.1111/jam.156092022
35547150Overexpression of BIT33_RS14560 Enhances the Biofilm Formation and Virulence of Acinetobacter baumannii.Yang R, Lai B, Liao K, Liu B, Huang L, Li S, Gu J, Lin Z, Chen Y, Wang S, Qiu Y, Deng J, Chen S, Zhuo C, Zhou YFront Microbiol10.3389/fmicb.2022.8677702022
Pathogenicity35841669Synthesis and biological evaluation of antibacterial activity of novel clarithromycin derivatives incorporating 1,2,3-triazole moieties at the 4''- and 11-OH positions.Qin Y, Sun M, Zhang N, Yang Y, Ma PBioorg Chem10.1016/j.bioorg.2022.1060202022Anti-Bacterial Agents/chemistry, Azithromycin, *Clarithromycin/pharmacology, Humans, Microbial Sensitivity Tests, Molecular Docking Simulation, Molecular Structure, *Staphylococcal Infections, Staphylococcus aureus, Structure-Activity Relationship, Triazoles/pharmacology
Pathogenicity35884232Profiling Antibiotic Resistance in Acinetobacter calcoaceticus.Glover JS, Ticer TD, Engevik MAAntibiotics (Basel)10.3390/antibiotics110709782022
Transcriptome35971084Transcriptomic analysis reveals the regulatory role of quorum sensing in the Acinetobacter baumannii ATCC 19606 via RNA-seq.Xiong L, Yi F, Yu Q, Huang X, Ao K, Wang Y, Xie YBMC Microbiol10.1186/s12866-022-02612-z2022*Acinetobacter baumannii, Bacterial Proteins/genetics/metabolism, Biofilms, Gene Expression Regulation, Bacterial, Quorum Sensing/genetics, RNA-Seq, TranscriptomeMetabolism
36106080Cinnamaldehyde derivatives act as antimicrobial agents against Acinetobacter baumannii through the inhibition of cell division.Chai WC, Whittall JJ, Polyak SW, Foo K, Li X, Dutschke CJ, Ogunniyi AD, Ma S, Sykes MJ, Semple SJ, Venter HFront Microbiol10.3389/fmicb.2022.9679492022
Genetics36148435Genome Sequence and Characterization of Acinetobacter Phage DMU1.Pehde BM, Niewohner D, Keomanivong FE, Carruthers MDPhage (New Rochelle)10.1089/phage.2020.00432021
Metabolism36173300Acinetobacter baumannii and Cefiderocol, between Cidality and Adaptability.Stracquadanio S, Bonomo C, Marino A, Bongiorno D, Privitera GF, Bivona DA, Mirabile A, Bonacci PG, Stefani SMicrobiol Spectr10.1128/spectrum.02347-222022*Acinetobacter baumannii/genetics/metabolism, beta-Lactamase Inhibitors/pharmacology, Penicillin-Binding Proteins/pharmacology, Microbial Sensitivity Tests, Cephalosporins/pharmacology, beta-Lactamases/genetics, Anti-Bacterial Agents/pharmacology, Drug Resistance, Multiple, Bacterial/genetics
Phylogeny36234819Molecular Characterization of Bacterial Isolates from Soil Samples and Evaluation of their Antibacterial Potential against MDRS.Sadiqi S, Hamza M, Ali F, Alam S, Shakeela Q, Ahmed S, Ayaz A, Ali S, Saqib S, Ullah F, Zaman WMolecules10.3390/molecules271962812022Anti-Bacterial Agents/chemistry/pharmacology, Ciprofloxacin, Complex Mixtures, Escherichia coli, *Methicillin-Resistant Staphylococcus aureus, Microbial Sensitivity Tests, Nucleotides, Oxalic Acid, Palmitic Acid, Phenols, Phylogeny, Propionates, Soil
Phylogeny36306681Analysis of virulence proteins in pathogenic Acinetobacter baumannii to provide early warning of zoonotic risk.Zou D, Chang J, Lu S, Xu J, Hu P, Zhang K, Sun X, Guo W, Li Y, Liu Z, Ren HMicrobiol Res10.1016/j.micres.2022.1272222022Mice, Animals, *Acinetobacter baumannii/genetics, Virulence/genetics, Proteomics, Phylogeny, Mice, Inbred ICR, Virulence Factors/genetics/metabolism, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization/methods, Protease InhibitorsMetabolism
36398565Chitosan-Placental ECM Composite Thermos-Responsive Hydrogel as a Biomimetic Wound Dressing with Angiogenic Property.Azadbakht A, Alizadeh S, Aliakbar Ahovan Z, Khosrowpour Z, Majidi M, Pakzad S, Shojaei S, Chauhan NPS, Jafari M, Gholipourmalekabadi MMacromol Biosci10.1002/mabi.2022003862022
36401642A novel pentavalent vaccine candidate completely protects against Acinetobacter baumannii in a mouse model of peritonitis.Hagag YA, Said HS, Kenawy HI, Hassan RAppl Microbiol Biotechnol10.1007/s00253-022-12231-32022Mice, Animals, *Acinetobacter baumannii, Vaccines, Combined
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Reference

@idauthorscataloguedoi/urltitlejournalpubmed
9084Curators of the DSMZLeibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSM 30007)https://www.dsmz.de/collection/catalogue/details/culture/DSM-30007
20215Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.10.1099/ijsem.0.004332List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ
20218Verslyppe, B., De Smet, W., De Baets, B., De Vos, P., Dawyndt P.10.1016/j.syapm.2013.11.002StrainInfo introduces electronic passports for microorganisms.Syst Appl Microbiol. 37: 42-50 201424321274
42141Curators of the CIPhttps://brclims.pasteur.fr/brcWeb/souche/detail/1/10505
66792Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmannhttps://diaspora-project.de/progress.html#genomesAutomatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information)
67770Curators of the JCMhttps://jcm.brc.riken.jp/en/
68369Automatically annotated from API 20NE
68371Automatically annotated from API 50CH acid
68382Automatically annotated from API zym
69479João F Matias Rodrigues, Janko Tackmann,Gregor Rot, Thomas SB Schmidt, Lukas Malfertheiner, Mihai Danaila,Marija Dmitrijeva, Daniela Gaio, Nicolas Näpflin and Christian von Mering. University of Zurich.https://microbeatlas.org/MicrobeAtlas 1.0 beta
69480Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmannhttps://diaspora-project.de/progress.html#genomesPredictions based on genome sequence made in the Diaspora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information)
69481Xiao-Yin To, René Mreches, Martin Binder, Alice C. McHardy, Philipp C. Münch10.21203/rs.3.rs-2527258/v1Predictions based on the model GenomeNet Sporulation v. 1
77520Reimer, L.C., Lissin, A.,Schober, I., Witte,J.F., Podstawka, A., Lüken, H., Bunk, B.,Overmann, J.10.60712/SI-ID92085.1StrainInfo: A central database for resolving microbial strain identifiers
116742Curators of the CIPCollection of Institut Pasteur (CIP 70.34)https://catalogue-crbip.pasteur.fr/fiche_catalogue.xhtml?crbip=CIP%2070.34