Strain identifier

BacDive ID: 16212

Type strain: No

Species: Streptomyces avermitilis

Strain Designation: MA-4848

Strain history: <- ATCC (Streptomyces avermitilis) <- Merck, MA-4848

NCBI tax ID(s): 33903 (species)

For citation purpose refer to the digital object identifier (doi) of the current version.
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General

@ref: 10308

BacDive-ID: 16212

DSM-Number: 41443

keywords: Bacteria, mesophilic

description: Streptomyces avermitilis MA-4848 is a mesophilic bacterium of the family Streptomycetaceae.

NCBI tax id

  • NCBI tax id: 33903
  • Matching level: species

strain history

  • @ref: 10308
  • history: <- ATCC (Streptomyces avermitilis) <- Merck, MA-4848

doi: 10.13145/bacdive16212.20230509.8.1

Name and taxonomic classification

LPSN

  • @ref: 20215
  • description: domain/bacteria
  • keyword: phylum/actinomycetota
  • domain: Bacteria
  • phylum: Actinomycetota
  • class: Actinomycetes
  • order: Kitasatosporales
  • family: Streptomycetaceae
  • genus: Streptomyces
  • species: Streptomyces avermitilis
  • full scientific name: Streptomyces avermitilis (ex Burg et al. 1979) Kim and Goodfellow 2002
  • synonyms

    • @ref: 20215
    • synonym: Streptomyces avermectinius

@ref: 10308

domain: Bacteria

phylum: Actinobacteria

class: Actinobacteria

order: Actinomycetales

family: Streptomycetaceae

genus: Streptomyces

species: Streptomyces avermitilis

full scientific name: Streptomyces avermitilis (ex Burg et al. 1979) Kim and Goodfellow 2002

strain designation: MA-4848

type strain: no

Culture and growth conditions

culture medium

  • @ref: 10308
  • name: OATMEAL AGAR (DSMZ Medium 425)
  • growth: yes
  • link: https://mediadive.dsmz.de/medium/425
  • composition: Name: OATMEAL AGAR (DSMZ Medium 425) Composition: Agar 15.0 g/l Oatmeal 10.0 g/l Oat flakes 10.0 g/l Distilled water

culture temp

  • @ref: 10308
  • growth: positive
  • type: growth
  • temperature: 28
  • range: mesophilic

Physiology and metabolism

compound production

@refcompound
10308C-076 and derivatives
20216Antibiotic C-076
20216Antibiotic C-076 derivatives

Safety information

risk assessment

  • @ref: 10308
  • biosafety level: 1
  • biosafety level comment: Risk group (German classification)

External links

@ref: 10308

culture collection no.: DSM 41443, ATCC 31272, IMET 43840

straininfo link

  • @ref: 85273
  • straininfo: 45902

literature

topicPubmed-IDtitleauthorsjournalyearmeshtopic2DOI
Enzymology10883272[Selection of high avermectins producing strain and identification of avermectin B1].Song Y, Cao GM, Chen Z, Li JLSheng Wu Gong Cheng Xue Bao2000Anthelmintics/*isolation & purification, Fermentation, Ivermectin/*analogs & derivatives/chemistry/isolation & purification/metabolism, Magnetic Resonance Spectroscopy, Streptomyces/*metabolismPhylogeny
12838613[Development of a system of plasmid transfer in the strains Streptomyces avermitilis ATCC 31272 and Saccharopolyspora erythraea ATCC 11635 by the method of intergeneric conjugation].Voeikova TA, Emel'ianova LK, Kudriavtseva EAGenetika2003Attachment Sites, Microbiological, Chromosomes, Bacterial, *Conjugation, Genetic, Escherichia coli/cytology/genetics, Genes, Bacterial, Genetic Vectors, Plasmids/*genetics, Saccharopolyspora/cytology/*genetics, Streptomyces/cytology/*genetics, Transformation, Bacterial
Metabolism12968333Direct production of ivermectin-like drugs after domain exchange in the avermectin polyketide synthase of Streptomyces avermitilis ATCC31272.Gaisser S, Kellenberger L, Kaja AL, Weston AJ, Lill RE, Wirtz G, Kendrew SG, Low L, Sheridan RM, Wilkinson B, Galloway IS, Stutzman-Engwall K, McArthur HA, Staunton J, Leadlay PFOrg Biomol Chem2003Blotting, Southern, Drug Design, Fermentation, Genes, Bacterial, Ivermectin/*analogs & derivatives/*chemistry/*metabolism, Multienzyme Complexes/*chemistry/genetics/*metabolism, Mutation, Protein Structure, Tertiary, Streptomyces/genetics/*metabolismBiotechnology10.1039/b304022d
Enzymology15285607[Modulation of serine/threonine protein kinase activity in chloramphenicol-resistant mutants of Streptomyces avermitilis].Elizarov SM, Gavrilina AV, Danilenko VNMol Biol (Mosk)2004Chloramphenicol/*pharmacology, Drug Resistance, Microbial/genetics, Electrophoresis, Polyacrylamide Gel, Mutation, Phosphorylation, Protein Serine-Threonine Kinases/*metabolism, Streptomyces/*drug effects/enzymology/geneticsMetabolism
Metabolism16874544Catalytic domain of AfsKav modulates both secondary metabolism and morphologic differentiation in Streptomyces avermitilis ATCC 31272.Rajkarnikar A, Kwon HJ, Ryu YW, Suh JWCurr Microbiol2006Bacterial Proteins/genetics/metabolism, Catalytic Domain/*genetics, Genetic Complementation Test/methods, Ivermectin/analogs & derivatives/metabolism, Melanins/metabolism, Mutation/genetics, Protein Serine-Threonine Kinases/*genetics/metabolism, Spores, Bacterial/genetics/metabolism, Streptomyces/enzymology/*genetics/physiologyEnzymology10.1007/s00284-006-0062-1

Reference

@idauthorscataloguedoi/urltitle
10308Curators of the DSMZLeibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSM 41443)https://www.dsmz.de/collection/catalogue/details/culture/DSM-41443
20215Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.10.1099/ijsem.0.004332List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ
20216Curators of the HKIhttp://www.leibniz-hki.de/de/Collection Description Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie e. V. Hans-Knöll-Institut (HKI)
85273Reimer, L.C., Lissin, A.,Schober, I., Witte,J.F., Podstawka, A., Lüken, H., Bunk, B.,Overmann, J.10.60712/SI-ID45902.1StrainInfo: A central database for resolving microbial strain identifiers