Strain identifier

BacDive ID: 14967

Type strain: No

Species: Streptomyces albus subsp. albus

Strain Designation: 80,614

Strain history: KCC S-0703 <-- Kaken Chem. Co., 80614.

NCBI tax ID(s): 1081613 (strain), 67257 (subspecies)

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General

@ref: 10146

BacDive-ID: 14967

DSM-Number: 41398

keywords: genome sequence, 16S sequence, Bacteria, spore-forming, antibiotic compound production

description: Streptomyces albus subsp. albus 80 is a spore-forming bacterium that builds an aerial mycelium and produces antibiotic compounds.

NCBI tax id

NCBI tax idMatching level
1081613strain
67257subspecies

strain history

@refhistory
10146<- ATCC <- Kaken Chem. Co., Ltd., 80,614
67770KCC S-0703 <-- Kaken Chem. Co., 80614.

doi: 10.13145/bacdive14967.20240916.9.1

Name and taxonomic classification

LPSN

  • @ref: 20215
  • description: domain/bacteria
  • keyword: phylum/actinomycetota
  • domain: Bacteria
  • phylum: Actinomycetota
  • class: Actinomycetes
  • order: Kitasatosporales
  • family: Streptomycetaceae
  • genus: Streptomyces
  • species: Streptomyces albus subsp. albus
  • full scientific name: Streptomyces albus subsp. albus (Rossi Doria 1891) Nagatsu et al. 1962 (Approved Lists 1980)

@ref: 10146

domain: Bacteria

phylum: Actinobacteria

class: Actinobacteria

order: Actinomycetales

family: Streptomycetaceae

genus: Streptomyces

species: Streptomyces albus subsp. albus

full scientific name: Streptomyces albus subsp. albus (Rossi Doria 1891) Nagatsu et al. 1962

strain designation: 80,614

type strain: no

Morphology

cell morphology

  • @ref: 69480
  • gram stain: positive
  • confidence: 92.166

colony morphology

@refcolony colormedium used
69271Beige (1001), brown beige (1011)ISP 4
69271Beige (1001)ISP 5
69271Light ivory (1015) transparentISP 6
69271Sand yellow (1002)ISP 2
69271Sand yellow (1002)ISP 7
69271Sand yellow (1002), beige (1001), transparentsuter without tyrosine
69271Sand yellow (1002), brown beige (1011)ISP 3
69271Sand yellow (1002), transparentsuter with tyrosine

multicellular morphology

@refforms multicellular complexcomplex namecomplex colormedium name
69271yesAerial myceliumGrey white (9002)ISP 2
69271yesAerial myceliumGrey white (9002)ISP 3
69271yesAerial myceliumGrey white (9002)ISP 4
69271yesAerial myceliumGrey white (9002)ISP 5
69271noAerial myceliumISP 6
69271yesAerial myceliumGrey white (9002)ISP 7
69271noAerial myceliumsuter with tyrosine
69271noAerial myceliumsuter without tyrosine

pigmentation

@refproductionnamecolor
69271yesMelanin
69271yessoluble pigmentSand yellow (1002)

multimedia

@refmultimedia contentcaptionintellectual property rights
10146https://www.dsmz.de/microorganisms/photos/DSM_41398.jpgMedium 65 28°C© Leibniz-Institut DSMZ
69271DSM_41398_image3.jpegPlates (65, ISP2, ISP3, ISP4, ISP5, ISP7)Helmholtz-Zentrum für Infektionsforschung GmbH
69271DSM_41398_image4.jpegPlates (65, ISP2, ISP3, ISP4, ISP5, ISP7)Helmholtz-Zentrum für Infektionsforschung GmbH

Culture and growth conditions

culture medium

  • @ref: 10146
  • name: GYM STREPTOMYCES MEDIUM (DSMZ Medium 65)
  • growth: yes
  • link: https://mediadive.dsmz.de/medium/65
  • composition: Name: GYM STREPTOMYCES MEDIUM (DSMZ Medium 65) Composition: Agar 18.0 g/l Malt extract 10.0 g/l Yeast extract 4.0 g/l Glucose 4.0 g/l CaCO3 2.0 g/l Distilled water

culture temp

@refgrowthtypetemperature
10146positivegrowth28
67770positivegrowth28

Physiology and metabolism

oxygen tolerance

  • @ref: 69480
  • oxygen tolerance: aerobe
  • confidence: 91.107

spore formation

@refspore formationconfidence
69480yes91.062
69481yes100

compound production

@refcompound
10146salinomycine
10146salbostatin
20216Salinomycin
67770albostatin (US Pat. 5,091,524)

halophily

  • @ref: 69271
  • salt: NaCl
  • growth: positive
  • tested relation: growth
  • concentration: 0-2.5 %

metabolite utilization

@refChebi-IDmetaboliteutilization activitykind of utilization tested
6927122599arabinose-growth
6927162968cellulose-growth
6927128757fructose+growth
6927117234glucose+growth
6927117268inositol-growth
6927137684mannose+growth
6927116634raffinose+growth
6927126546rhamnose-growth
6927117992sucrose+growth
6927118222xylose+growth
6837917632nitrate-reduction
683794853esculin+hydrolysis
6837916199urea-hydrolysis
683795291gelatin+hydrolysis
6837917634D-glucose-fermentation
6837916988D-ribose-fermentation
6837965327D-xylose-fermentation
6837916899D-mannitol-fermentation
6837917306maltose-fermentation
6837917716lactose-fermentation
6837917992sucrose-fermentation
6837928087glycogen-fermentation

metabolite production

  • @ref: 67770
  • Chebi-ID: 80025
  • metabolite: salinomycin
  • production: yes

enzymes

@refvalueactivityec
68379gelatinase+
68379urease-3.5.1.5
68379beta-glucosidase+3.2.1.21
68379N-acetyl-beta-glucosaminidase+3.2.1.52
68379alpha-glucosidase+3.2.1.20
68379beta-galactosidase+3.2.1.23
68379beta-glucuronidase-3.2.1.31
68379alkaline phosphatase+3.1.3.1
68379pyrrolidonyl arylamidase-3.4.19.3
68379pyrazinamidase-3.5.1.B15
68382alkaline phosphatase+3.1.3.1
68382esterase (C 4)+
68382esterase lipase (C 8)+
68382lipase (C 14)+
68382leucine arylamidase+3.4.11.1
68382valine arylamidase+
68382trypsin+3.4.21.4
68382acid phosphatase+3.1.3.2
68382naphthol-AS-BI-phosphohydrolase+
68382alpha-galactosidase+3.2.1.22
68382beta-galactosidase+3.2.1.23
68382beta-glucuronidase-3.2.1.31
68382alpha-glucosidase+3.2.1.20
68382beta-glucosidase+3.2.1.21
68382N-acetyl-beta-glucosaminidase+3.2.1.52
68382alpha-mannosidase+3.2.1.24
68382alpha-fucosidase+3.2.1.51

API coryne

@refNITPYZPYRAPALbeta GURbeta GALalpha GLUbeta NAGESCUREGELGLURIBXYLMANMALLACSACGLYG
69271---+-++++-+--------

API zym

@refAlkaline phosphataseEsteraseEsterase LipaseLipaseLeucine arylamidaseValine arylamidaseCystine arylamidaseTrypsinalpha- ChymotrypsinAcid phosphataseNaphthol-AS-BI-phosphohydrolasealpha- Galactosidasebeta- Galactosidasebeta- Glucuronidasealpha- Glucosidasebeta- GlucosidaseN-acetyl-beta- glucosaminidasealpha- Mannosidasealpha- Fucosidase
69271+++++++/-++/-++++-+++++

Isolation, sampling and environmental information

isolation

@refsample typecountryorigin.countrycontinentgeographic location
10146soilJapanJPNAsia
67770SoilJapanJPNAsiaFuji City, Shizuoka Pref.

isolation source categories

  • Cat1: #Environmental
  • Cat2: #Terrestrial
  • Cat3: #Soil

Safety information

risk assessment

  • @ref: 10146
  • biosafety level: 1
  • biosafety level comment: Risk group (German classification)

Sequence information

16S sequences

  • @ref: 67770
  • description: Streptomyces albus subsp. albus strain JCM4703 16S ribosomal RNA gene, partial sequence
  • accession: HQ537062
  • length: 1390
  • database: nuccore
  • NCBI tax ID: 1081613

Genome sequences

@refdescriptionaccessionassembly leveldatabaseNCBI tax ID
66792Streptomyces albus DSM 41398GCA_000827005completencbi1888
66792Streptomyces albus DSM 413981888.4completepatric1888
66792Streptomyces albus DSM 413982872998510completeimg1888
66792Streptomyces albus albus DSM 413982582581519draftimg1888

Genome-based predictions

predictions

@reftraitmodeldescriptionpredictionconfidencetraining_data
69481spore-formingspore-formingAbility to form endo- or exosporesyes100no
69480gram-positivegram-positivePositive reaction to Gram-stainingyes92.166no
69480anaerobicanaerobicAbility to grow under anoxygenic conditions (including facultative anaerobes)no96.608no
69480aerobicaerobicAbility to grow under oxygenic conditions (including facultative aerobes)yes91.107no
69480spore-formingspore-formingAbility to form endo- or exosporesyes91.062no
69480thermophilicthermophileAbility to grow at temperatures above or equal to 45°Cno95no
69480flagellatedmotile2+Ability to perform flagellated movementno87.5no

External links

@ref: 10146

culture collection no.: DSM 41398, ATCC 21838, KCC S-0703, FERM P-419, JCM 4703, CGMCC 4.5716, KCTC 9015, NBRC 107858

straininfo link

  • @ref: 84076
  • straininfo: 37751

literature

topicPubmed-IDtitleauthorsjournalDOIyearmeshtopic2
Enzymology18156784Expression and characterization of trehalose biosynthetic modules in the adjacent locus of the salbostatin gene cluster.Choeng YH, Yang JY, Delcroix G, Kim YJ, Chang YK, Hong SKJ Microbiol Biotechnol70262007Bacterial Proteins/*genetics, Chromatography, Thin Layer, Enzymes/*genetics, Genomic Library, Molecular Sequence Data, *Multigene Family, Open Reading Frames, Sequence Analysis, DNA, Streptomyces/*enzymology/*genetics/metabolism, Streptomyces lividans/genetics, Trehalase/antagonists & inhibitors, Trehalose/*biosynthesisGenetics
Metabolism18648803Genetic organization of the putative salbostatin biosynthetic gene cluster including the 2-epi-5-epi-valiolone synthase gene in Streptomyces albus ATCC 21838.Choi WS, Wu X, Choeng YH, Mahmud T, Jeong BC, Lee SH, Chang YK, Kim CJ, Hong SKAppl Microbiol Biotechnol10.1007/s00253-008-1591-22008Acarbose/metabolism, Bacterial Proteins/*genetics/isolation & purification/metabolism, Cyclohexenes/*metabolism, Escherichia coli/genetics/metabolism, Gene Expression, Hexosamines/*metabolism, Molecular Sequence Data, *Multigene Family, Recombinant Fusion Proteins/genetics/isolation & purification/metabolism, Streptomyces/*enzymology/*geneticsEnzymology
Enzymology26459865Direct cloning and heterologous expression of the salinomycin biosynthetic gene cluster from Streptomyces albus DSM41398 in Streptomyces coelicolor A3(2).Yin J, Hoffmann M, Bian X, Tu Q, Yan F, Xia L, Ding X, Stewart AF, Muller R, Fu J, Zhang YSci Rep10.1038/srep150812015Chromosomes, Artificial, Bacterial, *Cloning, Molecular, *Gene Expression, *Genes, Bacterial, Genetic Vectors/genetics, *Multigene Family, Pyrans/*metabolism, Streptomyces coelicolor/*genetics/*metabolismMetabolism
Metabolism26969249Enhanced salinomycin production by adjusting the supply of polyketide extender units in Streptomyces albus.Lu C, Zhang X, Jiang M, Bai LMetab Eng10.1016/j.ymben.2016.02.0122016Acyl Coenzyme A/genetics/metabolism, Acyl-CoA Dehydrogenases/biosynthesis/genetics, Bacterial Proteins/biosynthesis/genetics, Metabolic Engineering, Polyketide Synthases/biosynthesis/genetics, Polyketides/*metabolism, Pyrans/*metabolism, *Streptomyces/genetics/metabolismBiotechnology
Genetics28401259Mechanism of salinomycin overproduction in Streptomyces albus as revealed by comparative functional genomics.Zhang X, Lu C, Bai LAppl Microbiol Biotechnol10.1007/s00253-017-8278-52017Biosynthetic Pathways/*genetics, Gene Expression Regulation, Bacterial, Genome, Bacterial, Genomics/*methods, Polyketides/*metabolism, Pyrans/*metabolism, Sequence Analysis, DNA, Streptomyces/*genetics/metabolismMetabolism
Biotechnology31552238Combinatorial Effect of ARTP Mutagenesis and Ribosome Engineering on an Industrial Strain of Streptomyces albus S12 for Enhanced Biosynthesis of Salinomycin.Zhang K, Mohsin A, Dai Y, Chen Z, Zhuang Y, Chu J, Guo MFront Bioeng Biotechnol10.3389/fbioe.2019.002122019

Reference

@idauthorscataloguedoi/urltitlejournalpubmed
10146Curators of the DSMZLeibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSM 41398)https://www.dsmz.de/collection/catalogue/details/culture/DSM-41398
20215Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.10.1099/ijsem.0.004332List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ
20216Curators of the HKIhttp://www.leibniz-hki.de/de/Collection Description Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie e. V. Hans-Knöll-Institut (HKI)
66792Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmannhttps://diaspora-project.de/progress.html#genomesAutomatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information)
66794Antje Chang, Lisa Jeske, Sandra Ulbrich, Julia Hofmann, Julia Koblitz, Ida Schomburg, Meina Neumann-Schaal, Dieter Jahn, Dietmar Schomburg10.1093/nar/gkaa1025BRENDA, the ELIXIR core data resource in 2021: new developments and updatesNucleic Acids Res. 49: D498-D508 202033211880
67770Curators of the JCMhttps://jcm.brc.riken.jp/en/
68379Automatically annotated from API Coryne
68382Automatically annotated from API zym
69271Wink, J.https://cdn.dsmz.de/wink/DSM%2041398.pdfCompendium of Actinobacteria. HZI-Helmholtz-Centre for Infection Research, Braunschweig
69480Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmannhttps://diaspora-project.de/progress.html#genomesPredictions based on genome sequence made in the Diaspora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information)
69481Xiao-Yin To, René Mreches, Martin Binder, Alice C. McHardy, Philipp C. Münch10.21203/rs.3.rs-2527258/v1Predictions based on the model GenomeNet Sporulation v. 1
84076Reimer, L.C., Lissin, A.,Schober, I., Witte,J.F., Podstawka, A., Lüken, H., Bunk, B.,Overmann, J.10.60712/SI-ID37751.1StrainInfo: A central database for resolving microbial strain identifiers