Strain identifier
BacDive ID: 14523
Type strain: 
Species: Staphylococcus epidermidis
Strain Designation: KH 11
Strain history: <- G. Peters and G. Pulverer, KH 11
NCBI tax ID(s): 1282 (species)
version 8.1 (current version)
General
@ref: 1344
BacDive-ID: 14523
DSM-Number: 3269
keywords: Bacteria, mesophilic, human pathogen
description: Staphylococcus epidermidis KH 11 is a mesophilic human pathogen that was isolated from infected catheter tip.
NCBI tax id
- NCBI tax id: 1282
- Matching level: species
strain history
- @ref: 1344
- history: <- G. Peters and G. Pulverer, KH 11
doi: 10.13145/bacdive14523.20230509.8.1
Name and taxonomic classification
LPSN
- @ref: 20215
- description: domain/bacteria
- keyword: phylum/bacillota
- domain: Bacteria
- phylum: Bacillota
- class: Bacilli
- order: Caryophanales
- family: Staphylococcaceae
- genus: Staphylococcus
- species: Staphylococcus epidermidis
- full scientific name: Staphylococcus epidermidis (Winslow and Winslow 1908) Evans 1916 (Approved Lists 1980)
synonyms
- @ref: 20215
- synonym: Albococcus epidermidis
@ref: 1344
domain: Bacteria
phylum: Firmicutes
class: Bacilli
order: Bacillales
family: Staphylococcaceae
genus: Staphylococcus
species: Staphylococcus epidermidis
full scientific name: Staphylococcus epidermidis (Winslow and Winslow 1908) Evans 1916
strain designation: KH 11
type strain: no
Culture and growth conditions
culture medium
| @ref | name | growth | link | composition |
|---|---|---|---|---|
| 1344 | COLUMBIA BLOOD MEDIUM (DSMZ Medium 693) | yes | https://mediadive.dsmz.de/medium/693 | Name: COLUMBIA BLOOD MEDIUM (DSMZ Medium 693) Composition: Defibrinated sheep blood 50.0 g/l Columbia agar base |
| 1344 | TRYPTICASE SOY YEAST EXTRACT MEDIUM (DSMZ Medium 92) | yes | https://mediadive.dsmz.de/medium/92 | Name: TRYPTICASE SOY YEAST EXTRACT MEDIUM (DSMZ Medium 92) Composition: Trypticase soy broth 30.0 g/l Agar 15.0 g/l Yeast extract 3.0 g/l Distilled water |
culture temp
- @ref: 1344
- growth: positive
- type: growth
- temperature: 37
- range: mesophilic
Physiology and metabolism
antibiogram
- @ref: 1344
- medium: Mueller-Hinton Agar
- incubation temperature: 37
- Penicillin G: 24
- oxacillin: 36
- ampicillin: 28
- ticarcillin: 30
- mezlocillin: 24-26
- cefalotin: 38
- cefazolin: 32
- cefotaxime: 32
- aztreonam: 0
- imipenem: 50
- tetracycline: 28
- chloramphenicol: 10-12
- gentamycin: 28
- amikacin: 24-26
- vancomycin: 20
- erythromycin: 30-32
- lincomycin: 32-34
- ofloxacin: 30
- norfloxacin: 32
- colistin: 8
- pipemidic acid: 20-22
- nitrofurantoin: 28
- bacitracin: 16-18
- polymyxin b: 10-12
- kanamycin: 12-14
- neomycin: 10
- doxycycline: 26
- ceftriaxone: 30-32
- clindamycin: 36-38
- fosfomycin: 40
- moxifloxacin: 34
- linezolid: 32-34
- nystatin: 0
- quinupristin/dalfopristin: 30
- teicoplanin: 16
- piperacillin/tazobactam: 32
compound production
- @ref: 1344
- compound: slime
metabolite utilization
| @ref | Chebi-ID | metabolite | utilization activity | kind of utilization tested |
|---|---|---|---|---|
| 68375 | 16199 | urea | + | hydrolysis |
| 68375 | 29016 | arginine | + | hydrolysis |
| 68375 | 18257 | ornithine | - | degradation |
| 68375 | 4853 | esculin | - | hydrolysis |
| 68375 | 17634 | D-glucose | + | fermentation |
| 68375 | 15824 | D-fructose | + | fermentation |
| 68375 | 16024 | D-mannose | + | fermentation |
| 68375 | 17306 | maltose | + | fermentation |
| 68375 | 17716 | lactose | + | fermentation |
| 68375 | 27082 | trehalose | - | fermentation |
| 68375 | 16899 | D-mannitol | - | fermentation |
| 68375 | 16634 | raffinose | - | fermentation |
| 68375 | 16988 | D-ribose | - | fermentation |
| 68375 | 17057 | cellobiose | - | fermentation |
| 68375 | 17632 | nitrate | + | reduction |
| 68375 | 17992 | sucrose | + | fermentation |
| 68375 | 32528 | turanose | + | fermentation |
| 68375 | 22599 | arabinose | - | fermentation |
metabolite production
- @ref: 68375
- Chebi-ID: 15688
- metabolite: acetoin
- production: yes
metabolite tests
- @ref: 68375
- Chebi-ID: 15688
- metabolite: acetoin
- voges-proskauer-test: +
enzymes
| @ref | value | activity | ec |
|---|---|---|---|
| 68375 | beta-glucuronidase | - | 3.2.1.31 |
| 68375 | pyrrolidonyl arylamidase | - | 3.4.19.3 |
| 68375 | alkaline phosphatase | + | 3.1.3.1 |
| 68375 | L-arginine arylamidase | - | |
| 68375 | beta-galactosidase | - | 3.2.1.23 |
| 68375 | beta-glucosidase | - | 3.2.1.21 |
| 68375 | ornithine decarboxylase | - | 4.1.1.17 |
| 68375 | arginine dihydrolase | + | 3.5.3.6 |
| 68375 | urease | + | 3.5.1.5 |
API ID32STA
| @ref | URE | ADH Arg | ODC | ESC | GLU | FRU | MNE | MAL | LAC | TRE | MAN | RAF | RIB | CEL | NIT | VP | beta GAL | ArgA | PAL | PyrA | NOVO | SAC | NAG | TUR | ARA | beta GUR |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1344 | + | + | - | - | + | + | + | + | + | - | - | - | - | - | + | + | - | - | + | - | - | + | - | + | - | - |
| 1344 | + | + | - | - | + | + | + | + | + | - | - | - | - | - | + | + | - | - | + | - | + | + | + | + | - | - |
Isolation, sampling and environmental information
isolation
- @ref: 1344
- sample type: infected catheter tip
isolation source categories
| Cat1 | Cat2 | Cat3 |
|---|---|---|
| #Infection | #Disease | |
| #Infection | #Medical device | #Catheter |
Safety information
risk assessment
- @ref: 1344
- pathogenicity human: yes
- pathogenicity animal: yes
- biosafety level: 2
- biosafety level comment: Risk group (German classification)
External links
@ref: 1344
culture collection no.: DSM 3269, PCM 2479
straininfo link
- @ref: 83654
- straininfo: 47713
literature
| topic | Pubmed-ID | title | authors | journal | DOI | year | mesh | topic2 |
|---|---|---|---|---|---|---|---|---|
| Metabolism | 1789899 | Evidence for degradation of synthetic polyurethanes by Staphylococcus epidermidis. | Jansen B, Schumacher-Perdreau F, Peters G, Pulverer G | Zentralbl Bakteriol | 10.1016/s0934-8840(11)80216-1 | 1991 | Absorption, Agglutination Tests, Bacterial Proteins/analysis, Catheters, Indwelling, Electrophoresis, Polyacrylamide Gel, Enzyme Induction, Humans, Polymers, Polyurethanes/*metabolism, Staphylococcus epidermidis/chemistry/enzymology/*metabolism, Surface Properties, Urease/biosynthesis | Enzymology |
| Pathogenicity | 4089818 | Anticoagulant properties of extracellular slime substance produced by Staphylococcus epidermidis. | Bykowska K, Ludwicka A, Wegrzynowicz Z, Lopaciuk S, Kopec M | Thromb Haemost | 1985 | Anticoagulants/*isolation & purification, Antithrombin III/pharmacology, Blood Coagulation/drug effects, Extracellular Space/metabolism, Hot Temperature, Humans, In Vitro Techniques, Protamines/pharmacology, Staphylococcus epidermidis/*metabolism, Thrombin/antagonists & inhibitors/pharmacology | Metabolism | |
| Pathogenicity | 11481290 | In vitro activity of fosfomycin in combination with various antistaphylococcal substances. | Grif K, Dierich MP, Pfaller K, Miglioli PA, Allerberger F | J Antimicrob Chemother | 10.1093/jac/48.2.209 | 2001 | Anti-Bacterial Agents/*pharmacology, Drug Combinations, Fosfomycin/*pharmacology, Humans, Microbial Sensitivity Tests/methods, Staphylococcus aureus/cytology/*drug effects, Staphylococcus epidermidis/cytology/*drug effects | |
| Pathogenicity | 12599021 | Granulocyte colony-stimulating factor for the treatment of biomaterial-associated staphylococcal infections in-vitro. | Schlobe A, Schnitzler N, Schweizer K, Rohde D | Urol Res | 10.1007/s00240-002-0289-7 | 2002 | Adult, Granulocyte Colony-Stimulating Factor/*pharmacology, Humans, In Vitro Techniques, Microspheres, Neutrophil Activation/drug effects, Neutrophils/immunology/microbiology, Phagocytosis/*drug effects, Recombinant Proteins/pharmacology, Staphylococcal Infections/*drug therapy/immunology, *Staphylococcus epidermidis | |
| Pathogenicity | 19146534 | In vitro anti-biofilm activity of Boswellia spp. oleogum resin essential oils. | Schillaci D, Arizza V, Dayton T, Camarda L, Di Stefano V | Lett Appl Microbiol | 10.1111/j.1472-765X.2008.02469.x | 2008 | Bacterial Adhesion/drug effects, Biofilms/*drug effects/growth & development, Boswellia/*chemistry, Candida albicans/drug effects/growth & development, Growth Inhibitors/*pharmacology, Microbial Sensitivity Tests, Microbial Viability, Oils, Volatile/*pharmacology, Staining and Labeling, Staphylococcus aureus/drug effects/growth & development, Staphylococcus epidermidis/drug effects/growth & development, Tetrazolium Salts/metabolism, Thiazoles/metabolism | Metabolism |
| Pathogenicity | 19548887 | Antimicrobial and antistaphylococcal biofilm activity from the sea urchin Paracentrotus lividus. | Schillaci D, Arizza V, Parrinello N, Di Stefano V, Fanara S, Muccilli V, Cunsolo V, Haagensen JJ, Molin S | J Appl Microbiol | 10.1111/j.1365-2672.2009.04394.x | 2010 | Animals, *Anti-Infective Agents/chemistry/isolation & purification/pharmacology, Biofilms/*drug effects, Cell Fractionation, Cytosol/chemistry, Microbial Sensitivity Tests, Microbial Viability/drug effects, Microscopy, Confocal, Paracentrotus/*cytology/immunology/*metabolism, Peptides/chemistry/*pharmacology, Staining and Labeling, Staphylococcal Infections/prevention & control, Staphylococcus aureus/*drug effects, Staphylococcus epidermidis/*drug effects, Thymosin/chemistry/genetics | Enzymology |
| Pathogenicity | 30418277 | Zirconium Nitride Coating Reduced Staphylococcus epidermidis Biofilm Formation on Orthopaedic Implant Surfaces: An In Vitro Study. | Pilz M, Staats K, Tobudic S, Assadian O, Presterl E, Windhager R, Holinka J | Clin Orthop Relat Res | 10.1097/CORR.0000000000000568 | 2019 | Anti-Bacterial Agents/*pharmacology, Bacterial Adhesion/drug effects, Biofilms/*drug effects/growth & development, Coated Materials, Biocompatible/*adverse effects, Joint Prosthesis/*adverse effects/microbiology, Materials Testing, Prosthesis Design, Prosthesis-Related Infections/microbiology/*prevention & control, Staphylococcal Infections/microbiology/*prevention & control, Staphylococcus epidermidis/*drug effects/growth & development, Surface Properties, Zirconium/*pharmacology | |
| 35585076 | Antimicrobial potential and osteoblastic cell growth on electrochemically modified titanium surfaces with nanotubes and selenium or silver incorporation. | Staats K, Pilz M, Sun J, Boiadjieva-Scherzer T, Kronberger H, Tobudic S, Windhager R, Holinka J | Sci Rep | 10.1038/s41598-022-11804-6 | 2022 | Anti-Bacterial Agents/chemistry/pharmacology, Durapatite/chemistry, *Nanotubes/chemistry, *Selenium/pharmacology, Silver/chemistry/pharmacology, Surface Properties, Titanium/chemistry/pharmacology |
Reference
| @id | authors | catalogue | doi/url | title |
|---|---|---|---|---|
| 1344 | Curators of the DSMZ | Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSM 3269) | https://www.dsmz.de/collection/catalogue/details/culture/DSM-3269 | |
| 20215 | Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M. | 10.1099/ijsem.0.004332 | List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ | |
| 68375 | Automatically annotated from API ID32STA | |||
| 83654 | Reimer, L.C., Lissin, A.,Schober, I., Witte,J.F., Podstawka, A., Lüken, H., Bunk, B.,Overmann, J. | 10.60712/SI-ID47713.1 | StrainInfo: A central database for resolving microbial strain identifiers |