Strain identifier

BacDive ID: 132687

Type strain: No

Species: Acinetobacter baumannii

Strain Designation: Piéchaud 5377, Piéchaud strain Rochefort

Strain history: CIP <- 1953, M. Piéchaud, Inst. Pasteur, Paris, France: strain Rochefort, Moraxella glucidolytica var. nonliquefaciens

NCBI tax ID(s): 400667 (strain), 470 (species)

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General

@ref: 24477

BacDive-ID: 132687

DSM-Number: 105126

keywords: genome sequence, Bacteria, obligate aerobe, mesophilic, Gram-negative

description: Acinetobacter baumannii Piéchaud 5377 is an obligate aerobe, mesophilic, Gram-negative bacterium that was isolated from cerebrospinal fluid, fatal case of meningitis.

NCBI tax id

NCBI tax idMatching level
400667strain
470species

strain history

@refhistory
24477<- LMG; LMG 1025 <- Torry Res. Station <- ATCC; ATCC 17978 <- M. Piéchaud; Piéchaud 5377
345731953, M. Piéchaud, Inst. Pasteur, Paris, France: strain Rochefort, Moraxella glucidolytica var. nonliquefaciens
116743CIP <- 1953, M. Piéchaud, Inst. Pasteur, Paris, France: strain Rochefort, Moraxella glucidolytica var. nonliquefaciens

doi: 10.13145/bacdive132687.20230509.8.1

Name and taxonomic classification

LPSN

  • @ref: 20215
  • description: domain/bacteria
  • keyword: phylum/pseudomonadota
  • domain: Bacteria
  • phylum: Pseudomonadota
  • class: Gammaproteobacteria
  • order: Pseudomonadales
  • family: Moraxellaceae
  • genus: Acinetobacter
  • species: Acinetobacter baumannii
  • full scientific name: Acinetobacter baumannii Bouvet and Grimont 1986

@ref: 24477

domain: Bacteria

phylum: Proteobacteria

class: Gammaproteobacteria

order: Pseudomonadales

family: Moraxellaceae

genus: Acinetobacter

species: Acinetobacter baumannii

full scientific name: Acinetobacter baumannii Bouvet and Grimont 1986

strain designation: Piéchaud 5377, Piéchaud strain Rochefort

type strain: no

Morphology

cell morphology

@refgram stainconfidencecell shapemotility
69480negative99.997
116743negativerod-shapedno

colony morphology

  • @ref: 116743

Culture and growth conditions

culture medium

@refnamegrowthlinkcomposition
24477COLUMBIA BLOOD MEDIUM (DSMZ Medium 693)yeshttps://mediadive.dsmz.de/medium/693Name: COLUMBIA BLOOD MEDIUM (DSMZ Medium 693) Composition: Defibrinated sheep blood 50.0 g/l Columbia agar base
34573MEDIUM 3 - Columbia agaryesColumbia agar (39.000 g);distilled water (1000.000 ml)
24477TRYPTICASE SOY YEAST EXTRACT MEDIUM (DSMZ Medium 92)yeshttps://www.dsmz.de/microorganisms/medium/pdf/DSMZ_Medium92.pdf
116743CIP Medium 3yeshttps://catalogue-crbip.pasteur.fr/fiche_milieu.xhtml?crbip=3
116743CIP Medium 72yeshttps://catalogue-crbip.pasteur.fr/fiche_milieu.xhtml?crbip=72

culture temp

@refgrowthtypetemperaturerange
24477positivegrowth37mesophilic
34573positivegrowth30mesophilic
116743positivegrowth25-45
116743nogrowth10psychrophilic

Physiology and metabolism

oxygen tolerance

  • @ref: 116743
  • oxygen tolerance: obligate aerobe

spore formation

@refspore formationconfidence
69481no100
69480no99.996

halophily

@refsaltgrowthtested relationconcentration
116743NaClpositivegrowth0-4 %
116743NaClnogrowth6 %
116743NaClnogrowth8 %
116743NaClnogrowth10 %

metabolite utilization

@refmetaboliteutilization activitykind of utilization testedChebi-ID
68371Potassium 5-ketogluconate-builds acid from
68371Potassium 2-ketogluconate-builds acid from
68371gluconate-builds acid from24265
68371L-arabitol-builds acid from18403
68371D-arabitol-builds acid from18333
68371L-fucose-builds acid from18287
68371D-fucose-builds acid from28847
68371D-tagatose-builds acid from16443
68371D-lyxose-builds acid from62318
68371turanose-builds acid from32528
68371gentiobiose-builds acid from28066
68371xylitol-builds acid from17151
68371glycogen-builds acid from28087
68371starch-builds acid from28017
68371raffinose-builds acid from16634
68371melezitose-builds acid from6731
68371inulin-builds acid from15443
68371trehalose-builds acid from27082
68371sucrose-builds acid from17992
68371melibiose-builds acid from28053
68371lactose-builds acid from17716
68371maltose-builds acid from17306
68371cellobiose-builds acid from17057
68371salicin-builds acid from17814
68371esculin-builds acid from4853
68371arbutin-builds acid from18305
68371amygdalin-builds acid from27613
68371N-acetylglucosamine-builds acid from59640
68371methyl alpha-D-glucopyranoside-builds acid from320061
68371methyl alpha-D-mannoside-builds acid from43943
68371D-sorbitol-builds acid from17924
68371D-mannitol-builds acid from16899
68371myo-inositol-builds acid from17268
68371galactitol-builds acid from16813
68371L-rhamnose-builds acid from62345
68371L-sorbose-builds acid from17266
68371D-mannose-builds acid from16024
68371D-fructose-builds acid from15824
68371D-glucose-builds acid from17634
68371D-galactose-builds acid from12936
68371methyl beta-D-xylopyranoside-builds acid from74863
68371ribitol-builds acid from15963
68371L-xylose-builds acid from65328
68371D-xylose-builds acid from65327
68371D-ribose-builds acid from16988
68371L-arabinose-builds acid from30849
68371D-arabinose-builds acid from17108
68371erythritol-builds acid from17113
68371glycerol-builds acid from17754
68369malate+assimilation25115
68369adipate-assimilation17128
68369decanoate+assimilation27689
68369gluconate+assimilation24265
68369maltose-assimilation17306
68369N-acetylglucosamine-assimilation59640
68369D-mannitol-assimilation16899
68369D-mannose-assimilation16024
68369L-arabinose-assimilation30849
68369D-glucose-assimilation17634
68369esculin-hydrolysis4853
68369urea-hydrolysis16199
68369arginine-hydrolysis29016
68369D-glucose-fermentation17634
68369tryptophan-energy source27897
68369nitrate-reduction17632
116743nitrate-reduction17632
116743nitrite-reduction16301
116743glucose-degradation17234
116743nitrate-respiration17632

antibiotic resistance

  • @ref: 116743
  • metabolite: 0129 (2,4-Diamino-6,7-di-iso-propylpteridine phosphate)
  • is antibiotic: yes
  • is sensitive: no
  • is resistant: yes

metabolite production

@refChebi-IDmetaboliteproduction
6836935581indoleno
11674335581indoleno

metabolite tests

@refChebi-IDmetaboliteindole testvoges-proskauer-testmethylred-test
6836935581indole-
11674315688acetoin-
11674317234glucose-

enzymes

@refvalueactivityec
68369cytochrome oxidase-1.9.3.1
68369beta-glucosidase-3.2.1.21
68369urease-3.5.1.5
68369arginine dihydrolase-3.5.3.6
116743oxidase-
116743beta-galactosidase-3.2.1.23
116743gelatinase-
116743catalase+1.11.1.6
116743gamma-glutamyltransferase+2.3.2.2
116743urease+3.5.1.5
68382alkaline phosphatase+3.1.3.1
68382esterase (C 4)+
68382esterase lipase (C 8)+
68382lipase (C 14)-
68382leucine arylamidase+3.4.11.1
68382valine arylamidase+
68382cystine arylamidase+3.4.11.3
68382trypsin-3.4.21.4
68382alpha-chymotrypsin-3.4.21.1
68382acid phosphatase+3.1.3.2
68382naphthol-AS-BI-phosphohydrolase+
68382alpha-galactosidase-3.2.1.22
68382beta-galactosidase-3.2.1.23
68382beta-glucuronidase-3.2.1.31
68382alpha-glucosidase-3.2.1.20
68382beta-glucosidase-3.2.1.21
68382N-acetyl-beta-glucosaminidase-3.2.1.52
68382alpha-mannosidase-3.2.1.24
68382alpha-fucosidase-3.2.1.51

API zym

@refControlAlkaline phosphataseEsteraseEsterase LipaseLipaseLeucine arylamidaseValine arylamidaseCystine arylamidaseTrypsinalpha- ChymotrypsinAcid phosphataseNaphthol-AS-BI-phosphohydrolasealpha- Galactosidasebeta- Galactosidasebeta- Glucuronidasealpha- Glucosidasebeta- GlucosidaseN-acetyl-beta- glucosaminidasealpha- Mannosidasealpha- Fucosidase
116743-+++-+++--++--------

API 20NE

@refNO3TRPGLU_ FermADH ArgUREESCGELPNPGGLU_ AssimARAMNEMANNAGMALGNTCAPADIMLTCITPACOX
24477--------------++-+++-
24477------+-------++-+++-
24477--------------++-+++-

API 50CHac

@refGLYERYDARALARARIBDXYLLXYLADOMDXGALGLUFRUMNESBERHADULINOMANSORMDMMDGNAGAMYARBESCSALCELMALLACMELSACTREINUMLZRAFAMDGLYGXLTGENTURLYXTAGDFUCLFUCDARLLARLGNT2KG5KG
116743-------------------------------------------------

API biotype100

@refGLUFRUGALTREMNESBEMELSACRAFMTEMALLACLTEMbGaMaGaCELGENMbGuESCRIBARAXYLPLERHAFUCMLZDARLLARLXLTDULTAGGLYINOMANMTLTURSORADOHBGLYXERYMDG3MDGSATMUCLTATDTATMTATDMLTLMLTCATETATETTECITGRTGAT2KG5KGTRYNAGGNTPACPATpOBEQATGTEmOBEBATPPATCMTTGEBETPCEABTHINLATCAPCYTHISSUCFUMGREGYTAVTETNTTNGLNITA3OBUAPTGTTPRODALALALASERMNTPROPTYR2KT
116743--------------------+----------------------++---++++++------++++---+----++-+++-+++------+++++++++++

Isolation, sampling and environmental information

isolation

@refsample typecountryorigin.countrycontinent
24477cerebrospinal fluid, fatal case of meningitis
116743Human, Cerebrospinal fluidFranceFRAEurope

isolation source categories

Cat1Cat2Cat3
#Infection#Disease#Meningitis
#Host Body Product#Fluids#Cerebrospinal fluid

Safety information

risk assessment

@refbiosafety levelbiosafety level comment
244772Risk group (German classification)
1167431Risk group (French classification)

Sequence information

Genome sequences

@refdescriptionaccessionassembly leveldatabaseNCBI tax ID
66792Acinetobacter baumannii ATCC 17978GCA_014672775completencbi470
66792Acinetobacter baumannii ATCC 17978-VUGCA_001593425completencbi470
66792Acinetobacter baumannii ATCC 17978-mffGCA_001077675completencbi470
66792Acinetobacter baumannii ATCC 17978GCA_011067065completencbi470
66792Acinetobacter baumannii ATCC 17978GCA_013372085completencbi400667
66792Acinetobacter baumannii ATCC 17978 ATCC 17978 substr. PMR-HighGCA_004797155completencbi400667
66792Acinetobacter baumannii ATCC 17978 ATCC 17978 substr. PMR-LowGCA_004794275chromosomencbi400667
66792Acinetobacter baumannii ATCC 17978 ATCC 17978 substr. Lab-WTGCA_004794235chromosomencbi400667
66792Acinetobacter baumannii ATCC 17978 Acinetobacter baumannii ATCC17978GCA_902728005contigncbi400667
66792Acinetobacter baumannii ATCC 17978GCA_000015425completencbi400667
66792Acinetobacter baumannii ATCC 17978400667.7completepatric400667
66792Acinetobacter baumannii ATCC 17978400667.92completepatric400667
66792Acinetobacter baumannii ATCC 17978400667.121completepatric400667
66792Acinetobacter baumannii ATCC 17978400667.93completepatric400667
66792Acinetobacter baumannii ATCC 17978400667.91completepatric400667
66792Acinetobacter baumannii ATCC 17978400667.80plasmidpatric400667
66792Acinetobacter baumannii ATCC 17978400667.79plasmidpatric400667
66792Acinetobacter baumannii ATCC 17978 strain Acinetobacter baumannii ATCC17978400667.143wgspatric400667
66792Acinetobacter baumannii strain 17978UN470.13902completepatric470
66792Acinetobacter baumannii strain AB042470.3044completepatric470
66792Acinetobacter baumannii strain AB043470.9249completepatric470
66792Acinetobacter baumannii strain ATCC 17978470.11103completepatric470
66792Acinetobacter baumannii strain ATCC 17978470.1999wgspatric470
66792Acinetobacter baumannii strain ATCC 17978470.12190completepatric470
66792Acinetobacter baumannii strain ATCC 17978-mff470.1575completepatric470
66792Acinetobacter baumannii strain ATCC 17978-mff470.4376plasmidpatric470
66792Acinetobacter baumannii strain XH181470.2656wgspatric470
66792Acinetobacter baumannii strain XH182470.2655wgspatric470
66792Acinetobacter baumannii strain XH183470.2658wgspatric470
66792Acinetobacter baumannii strain XH184470.2659wgspatric470
66792Acinetobacter baumannii strain XH191470.2657wgspatric470
66792Acinetobacter baumannii strain XH192470.2654wgspatric470
66792Acinetobacter baumannii strain XH193470.2652wgspatric470
66792Acinetobacter baumannii strain XH198470.2653wgspatric470
66792Acinetobacter baumannii ATCC 17978640069301completeimg400667
66792Acinetobacter baumannii ATCC 17978-mff2671180557completeimg470
66792Acinetobacter baumannii ATCC 179782860756204completeimg400667
66792Acinetobacter baumannii ATCC 17978GCA_020912005completencbi470
66792Acinetobacter baumannii ATCC17978-VUBGCA_022467135completencbi470
66792Acinetobacter baumannii ATCC 17978GCA_026167785completencbi400667
66792Acinetobacter baumannii ATCC 17978GCA_026167805completencbi400667
66792Acinetobacter baumannii strain ATCC 17978470.15028completepatric470
66792Acinetobacter baumannii ATCC17978 TnAraC-H0N27_12600GCA_029459615completencbi470

Genome-based predictions

predictions

traitpredictionconfidencetraining_data
spore-formingno100no
flagellatedno93.635no
gram-positiveno97.258no
anaerobicno98.943no
aerobicyes94.73no
halophileno91.259no
spore-formingno96.861no
thermophileno99.904yes
glucose-utilno66.764no
motileno90.529no
glucose-fermentno83.104yes

External links

@ref: 24477

culture collection no.: DSM 105126, ATCC 17978, CIP 53.77, LMG 1025, NCDC KC755, Bouvet and Grimont 8

straininfo link

  • @ref: 90995
  • straininfo: 13527

literature

topicPubmed-IDtitleauthorsjournalDOIyearmeshtopic2
Pathogenicity18411315Whole-genome pyrosequencing of an epidemic multidrug-resistant Acinetobacter baumannii strain belonging to the European clone II group.Iacono M, Villa L, Fortini D, Bordoni R, Imperi F, Bonnal RJ, Sicheritz-Ponten T, De Bellis G, Visca P, Cassone A, Carattoli AAntimicrob Agents Chemother10.1128/AAC.01643-072008Acinetobacter/genetics, Acinetobacter Infections/drug therapy/epidemiology/microbiology, Acinetobacter baumannii/classification/*drug effects/*genetics/pathogenicity, Bacterial Proteins/genetics, Cross Infection/drug therapy/epidemiology/microbiology, DNA, Bacterial/genetics, Disease Outbreaks, Drug Resistance, Multiple, Bacterial/*genetics, Europe/epidemiology, *Genome, Bacterial, Humans, Membrane Transport Proteins/genetics, Molecular Sequence Data, Plasmids/genetics, Sequence Analysis, DNA, Species Specificity, Virulence/geneticsGenetics
Genetics18610651Amplification of a single-locus variable-number direct repeats with restriction fragment length polymorphism (DR-PCR/RFLP) for genetic typing of Acinetobacter baumannii strains.Nowak-Zaleska A, Krawczyk B, Kotlowski R, Mikucka A, Gospodarek EPol J Microbiol2008Acinetobacter baumannii/classification/*genetics, Bacterial Typing Techniques/*methods, Base Sequence, Chromosomes, Bacterial, DNA, Bacterial/analysis, Electrophoresis, Gel, Pulsed-Field, Genotype, Molecular Sequence Data, Polymerase Chain Reaction, *Polymorphism, Restriction Fragment Length, *Repetitive Sequences, Nucleic Acid, Sequence Analysis, DNAEnzymology
Genetics19020910Variable number tandem repeat loci providing discrimination within widespread genotypes of Acinetobacter baumannii.Turton JF, Matos J, Kaufmann ME, Pitt TLEur J Clin Microbiol Infect Dis10.1007/s10096-008-0659-32008Acinetobacter baumannii/*classification/*genetics, *Bacterial Typing Techniques, DNA Fingerprinting/*methods, DNA, Bacterial/*genetics, Electrophoresis, Gel, Pulsed-Field, Genotype, Humans, *Minisatellite Repeats, Molecular Epidemiology/methods, Sensitivity and SpecificityEnzymology
Pathogenicity19022777ATPase genes of diverse multidrug-resistant Acinetobacter baumannii isolates frequently harbour integrated DNA.Shaikh F, Spence RP, Levi K, Ou HY, Deng Z, Towner KJ, Rajakumar KJ Antimicrob Chemother10.1093/jac/dkn4812008Acinetobacter baumannii/*enzymology/*genetics, Adenosine Triphosphatases/*genetics, Bacterial Proteins/*genetics, Cluster Analysis, DNA Fingerprinting, DNA, Bacterial/chemistry/genetics, *DNA, Recombinant, Electrophoresis, Gel, Pulsed-Field, Humans, Molecular Sequence Data, *Mutagenesis, Insertional, Polymorphism, Genetic, Random Amplified Polymorphic DNA Technique, Sequence Analysis, DNAEnzymology
Genetics19528270Resistance to colistin in Acinetobacter baumannii associated with mutations in the PmrAB two-component system.Adams MD, Nickel GC, Bajaksouzian S, Lavender H, Murthy AR, Jacobs MR, Bonomo RAAntimicrob Agents Chemother10.1128/AAC.00284-092009Acinetobacter baumannii/*drug effects/*genetics, Anti-Bacterial Agents/pharmacology, Bacterial Proteins/*genetics/physiology, Colistin/*pharmacology, DNA Mutational Analysis, Drug Resistance, Bacterial/genetics, Genome, Bacterial/genetics, Mutation, Reverse Transcriptase Polymerase Chain Reaction, Transcription Factors/*genetics/physiologyPathogenicity
Metabolism197857482-DE analysis indicates that Acinetobacter baumannii displays a robust and versatile metabolism.Soares NC, Cabral MP, Parreira JR, Gayoso C, Barba MJ, Bou GProteome Sci10.1186/1477-5956-7-372009
Metabolism20108952Associating growth-phase-related changes in the proteome of Acinetobacter baumannii with increased resistance to oxidative stress.Soares NC, Cabral MP, Gayoso C, Mallo S, Rodriguez-Velo P, Fernandez-Moreira E, Bou GJ Proteome Res10.1021/pr901116r2010Acinetobacter baumannii/drug effects/*growth & development/*metabolism, Analysis of Variance, Anti-Bacterial Agents, Bacterial Proteins/classification/*metabolism, Electrophoresis, Gel, Two-Dimensional, Hydrogen Peroxide/pharmacology, Isotope Labeling, Microbial Viability, Oxidative Stress/drug effects/*physiology, Proteome/*metabolism, Proteomics/*methods, Reactive Nitrogen Species/metabolism, Reactive Oxygen Species/metabolism, Reverse Transcriptase Polymerase Chain Reaction, Spectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationProteome
Pathogenicity20861141Repurposing FDA-approved drugs to combat drug-resistant Acinetobacter baumannii.Chopra S, Torres-Ortiz M, Hokama L, Madrid P, Tanga M, Mortelmans K, Kodukula K, Galande AKJ Antimicrob Chemother10.1093/jac/dkq3532010Acinetobacter Infections/microbiology, Acinetobacter baumannii/*drug effects, Anti-Bacterial Agents/*pharmacology, Cross Infection/*microbiology, Drug Approval, Drug Discovery/*methods, *Drug Resistance, Multiple, Bacterial, Humans, Microbial Sensitivity Tests, Tyrothricin/*pharmacology, United States, United States Food and Drug Administration
Pathogenicity20889755The opportunistic human pathogen Acinetobacter baumannii senses and responds to light.Mussi MA, Gaddy JA, Cabruja M, Arivett BA, Viale AM, Rasia R, Actis LAJ Bacteriol10.1128/JB.00917-102010Acinetobacter baumannii/genetics/*physiology/*radiation effects, Amino Acid Sequence, Bacterial Proteins/chemistry/genetics/metabolism, Biofilms, Color, Gene Expression Regulation, Bacterial/radiation effects, Humans, *Light, Photoreceptors, Microbial, Phototropism/*physiology, Protein Structure, Tertiary, TemperatureMetabolism
Pathogenicity21212056Molecular cloning and functional characterization of two novel membrane fusion proteins in conferring antimicrobial resistance in Acinetobacter baumannii.Srinivasan VB, Rajamohan G, Pancholi P, Marcon M, Gebreyes WAJ Antimicrob Chemother10.1093/jac/dkq4692011Acinetobacter baumannii/*drug effects/*genetics, Anti-Bacterial Agents/pharmacology, Bacterial Proteins/*genetics/*metabolism, Cloning, Molecular, DNA, Bacterial/chemistry/genetics, *Drug Resistance, Bacterial, Escherichia coli/drug effects/genetics, Humans, Membrane Fusion Proteins/*genetics/*metabolism, Molecular Sequence Data, Mutagenesis, Insertional, Open Reading Frames, Sequence Analysis, DNAMetabolism
Metabolism21342532Investigation of the human pathogen Acinetobacter baumannii under iron limiting conditions.Eijkelkamp BA, Hassan KA, Paulsen IT, Brown MHBMC Genomics10.1186/1471-2164-12-1262011Acinetobacter baumannii/*genetics/growth & development/metabolism, Base Sequence, Binding Sites, Comparative Genomic Hybridization, *Gene Expression Profiling, Gene Expression Regulation, Bacterial, Genome, Bacterial, Iron/*metabolism, Multigene Family, Oligonucleotide Array Sequence Analysis, Open Reading Frames, Promoter Regions, Genetic, RNA, Bacterial/genetics, Siderophores/geneticsGenetics
Metabolism21518847Horizontal transfer of the OXA-24 carbapenemase gene via outer membrane vesicles: a new mechanism of dissemination of carbapenem resistance genes in Acinetobacter baumannii.Rumbo C, Fernandez-Moreira E, Merino M, Poza M, Mendez JA, Soares NC, Mosquera A, Chaves F, Bou GAntimicrob Agents Chemother10.1128/AAC.00929-102011Acinetobacter baumannii/*drug effects/*genetics/metabolism/ultrastructure, Bacterial Proteins/*genetics/metabolism, Carbapenems/*pharmacology, Cell Membrane/*metabolism/ultrastructure, Gene Transfer, Horizontal/genetics/*physiology, Microscopy, Electron, Transmission, Polymerase Chain Reaction, Transport Vesicles/*metabolism, beta-Lactamases/*genetics/metabolismPathogenicity
Metabolism21646482The pmrCAB operon mediates polymyxin resistance in Acinetobacter baumannii ATCC 17978 and clinical isolates through phosphoethanolamine modification of lipid A.Arroyo LA, Herrera CM, Fernandez L, Hankins JV, Trent MS, Hancock REAntimicrob Agents Chemother10.1128/AAC.00256-112011Acinetobacter baumannii/*drug effects/*genetics/isolation & purification/metabolism, Anti-Bacterial Agents/*pharmacology, Bacterial Proteins/genetics, Base Sequence, Chromatography, Thin Layer, Drug Resistance, Multiple, Bacterial, Ethanolamines/*metabolism, Gene Expression Regulation, Bacterial, Gene Knockout Techniques, Lipid A/chemistry/*metabolism, Mass Spectrometry, Microbial Sensitivity Tests, Molecular Sequence Data, *Operon, Polymyxins/*pharmacology, Reverse Transcriptase Polymerase Chain Reaction, Sequence Analysis, DNA, Transcription Factors/geneticsGenetics
Pathogenicity21947403Analysis of genes encoding penicillin-binding proteins in clinical isolates of Acinetobacter baumannii.Cayo R, Rodriguez MC, Espinal P, Fernandez-Cuenca F, Ocampo-Sosa AA, Pascual A, Ayala JA, Vila J, Martinez-Martinez LAntimicrob Agents Chemother10.1128/AAC.00459-112011Acinetobacter Infections/*microbiology, Acinetobacter baumannii/*drug effects/genetics/isolation & purification/metabolism, Amino Acid Sequence, Anti-Bacterial Agents/*pharmacology, Carbapenems/*pharmacology, Hospitals, Teaching, Humans, Microbial Sensitivity Tests, Molecular Sequence Data, Penicillin-Binding Proteins/chemistry/*genetics/metabolism, Point Mutation, Sequence Analysis, DNA, Spain, beta-Lactam Resistance/*geneticsMetabolism
Pathogenicity21996406Imipenem: a potent inducer of multidrug resistance in Acinetobacter baumannii.Kuo HY, Chang KC, Kuo JW, Yueh HW, Liou MLInt J Antimicrob Agents10.1016/j.ijantimicag.2011.08.0162011Acinetobacter Infections/microbiology, Acinetobacter baumannii/*drug effects/genetics/isolation & purification/metabolism, Anti-Bacterial Agents/*pharmacology, Bacterial Proteins/*genetics/metabolism, Carbapenems/pharmacology, Drug Resistance, Multiple, Bacterial/*drug effects/genetics, *Gene Expression Regulation, Bacterial, Humans, Imipenem/*pharmacology, Microbial Sensitivity Tests, Mutation, Nuclear Proteins, Reverse Transcriptase Polymerase Chain Reaction, Selection, Genetic, beta-Lactamases/genetics/metabolismMetabolism
Pathogenicity22089352Establishment of a novel target-based real-time quantitative PCR method for Acinetobacter baumannii detection.Zhang L, Ding G, Wei L, Pan X, Mei L, Zhang Y, Lu YDiagn Mol Pathol10.1097/PDM.0b013e31821bbb1e2011Acinetobacter Infections/diagnosis, Acinetobacter baumannii/genetics/*isolation & purification, *Bacterial Typing Techniques, Biofilms, DNA, Bacterial/analysis/genetics, Humans, Molecular Sequence Data, Polymerase Chain Reaction/*methods, Sensitivity and Specificity, Sequence Analysis, DNAGenetics
Metabolism22211672Characterization of the Acinetobacter baumannii growth phase-dependent and serum responsive transcriptomes.Jacobs AC, Sayood K, Olmsted SB, Blanchard CE, Hinrichs S, Russell D, Dunman PMFEMS Immunol Med Microbiol10.1111/j.1574-695X.2011.00926.x2012Acinetobacter Infections/blood/*microbiology, Acinetobacter baumannii/genetics/growth & development/metabolism/*physiology, Cell Adhesion/genetics, DNA, Bacterial/*genetics/metabolism, Drug Resistance, Microbial/genetics, Epithelial Cells/metabolism/microbiology, Gene Expression/genetics, Humans, Iron/metabolism, Oligonucleotide Array Sequence Analysis/methods, Pneumonia/genetics/metabolism/microbiology, Sepsis/genetics/metabolism/microbiology, *Transcriptome, Virulence/genetics, Virulence Factors/genetics/metabolismTranscriptome
Pathogenicity22240078Synergistic activity of coriander oil and conventional antibiotics against Acinetobacter baumannii.Duarte A, Ferreira S, Silva F, Domingues FCPhytomedicine10.1016/j.phymed.2011.11.0102012Acinetobacter baumannii/*drug effects, Anti-Bacterial Agents/*chemistry/pharmacology, Chloramphenicol/pharmacology, Ciprofloxacin/pharmacology, Coriandrum/*chemistry, Drug Synergism, Gentamicins/pharmacology, Microbial Sensitivity Tests, Piperacillin/pharmacology, Plant Oils/chemistry/*pharmacology, Tetracycline/pharmacology
Metabolism22366694Screening of nuclear targeting proteins in Acinetobacter baumannii based on nuclear localization signals.Moon DC, Gurung M, Lee JH, Lee YS, Choi CW, Kim SI, Lee JCRes Microbiol10.1016/j.resmic.2012.02.0012012Acinetobacter baumannii/chemistry/genetics/*metabolism, Animals, Bacterial Proteins/*chemistry/genetics/*metabolism, Bacteriological Techniques/*methods, COS Cells, Cell Line, Chlorocebus aethiops, Green Fluorescent Proteins/genetics/metabolism, Humans, Molecular Sequence Data, *Nuclear Localization Signals, Nuclear Proteins/chemistry/genetics/metabolism, Protein Transport, Recombinant Fusion Proteins/chemistry/genetics/metabolismPathogenicity
Metabolism22560766Surface-associated motility, a common trait of clinical isolates of Acinetobacter baumannii, depends on 1,3-diaminopropane.Skiebe E, de Berardinis V, Morczinek P, Kerrinnes T, Faber F, Lepka D, Hammer B, Zimmermann O, Ziesing S, Wichelhaus TA, Hunfeld KP, Borgmann S, Grobner S, Higgins PG, Seifert H, Busse HJ, Witte W, Pfeifer Y, Wilharm GInt J Med Microbiol10.1016/j.ijmm.2012.03.0032012Acinetobacter Infections/microbiology, Acinetobacter baumannii/genetics/isolation & purification/*physiology, Animals, Chromatography, High Pressure Liquid, DNA Transposable Elements, Diamines/*metabolism, Gene Knockout Techniques, Genetic Complementation Test, Humans, Lepidoptera, *Locomotion, Metabolic Networks and Pathways/genetics, Mutagenesis, Insertional, Virulence, Virulence Factors/metabolismPathogenicity
Metabolism22564848Deciphering the function of the outer membrane protein OprD homologue of Acinetobacter baumannii.Catel-Ferreira M, Nehme R, Molle V, Aranda J, Bouffartigues E, Chevalier S, Bou G, Jouenne T, De EAntimicrob Agents Chemother10.1128/AAC.06022-112012Acinetobacter baumannii/drug effects/genetics/*metabolism, Anti-Bacterial Agents/pharmacology, Bacterial Outer Membrane Proteins/genetics/*metabolism, Bleomycin/pharmacology, Kanamycin/pharmacology, Reverse Transcriptase Polymerase Chain ReactionPathogenicity
Metabolism22685409Identification of a general O-linked protein glycosylation system in Acinetobacter baumannii and its role in virulence and biofilm formation.Iwashkiw JA, Seper A, Weber BS, Scott NE, Vinogradov E, Stratilo C, Reiz B, Cordwell SJ, Whittal R, Schild S, Feldman MFPLoS Pathog10.1371/journal.ppat.10027582012Acinetobacter Infections/metabolism, Acinetobacter baumannii/*metabolism/*pathogenicity, Animals, Bacterial Proteins/*metabolism, *Biofilms, Blotting, Western, Gene Knockout Techniques, Glycoproteins/*metabolism, Glycosylation, Magnetic Resonance Spectroscopy, Mass Spectrometry, Membrane Proteins/metabolism, Mice, Mice, Inbred BALB C, Microscopy, Confocal, Polysaccharides, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization, Virulence
Metabolism22685614Nuclear translocation of Acinetobacter baumannii transposase induces DNA methylation of CpG regions in the promoters of E-cadherin gene.Moon DC, Choi CH, Lee SM, Lee JH, Kim SI, Kim DS, Lee JCPLoS One10.1371/journal.pone.00389742012Acinetobacter baumannii/enzymology/*genetics, Active Transport, Cell Nucleus, Animals, Bacterial Proteins/*genetics/metabolism, Blotting, Western, COS Cells, Cadherins/*genetics/metabolism, Cell Line, Tumor, Cell Nucleus/metabolism, Chlorocebus aethiops, CpG Islands/genetics, Cytoplasm/metabolism, *DNA Methylation, Down-Regulation, Green Fluorescent Proteins/genetics/metabolism, Humans, Microscopy, Confocal, Mutation, Nuclear Localization Signals/genetics/metabolism, Promoter Regions, Genetic/*genetics, Recombinant Fusion Proteins/genetics/metabolism, Transposases/*genetics/metabolismPathogenicity
Metabolism22825448Evaluation of the trimeric autotransporter Ata as a vaccine candidate against Acinetobacter baumannii infections.Bentancor LV, Routray A, Bozkurt-Guzel C, Camacho-Peiro A, Pier GB, Maira-Litran TInfect Immun10.1128/IAI.06096-112012Acinetobacter Infections/*prevention & control, Acinetobacter baumannii/drug effects/immunology/*metabolism, Animals, Antibodies, Bacterial/blood, Bacterial Adhesion, Bacterial Outer Membrane Proteins/genetics/*immunology/metabolism, Bacterial Vaccines/*immunology, Collagen Type IV, Drug Resistance, Multiple, Bacterial, Gene Expression Regulation, Bacterial/physiology, Membrane Proteins/*immunology/metabolism, Mice, Pneumonia, Bacterial/microbiology/prevention & control, RabbitsPathogenicity
Enzymology23014718Conversion of OXA-66 into OXA-82 in clinical Acinetobacter baumannii isolates and association with altered carbapenem susceptibility.Zander E, Chmielarczyk A, Heczko P, Seifert H, Higgins PGJ Antimicrob Chemother10.1093/jac/dks3822012Acinetobacter Infections/epidemiology/microbiology, Acinetobacter baumannii/classification/*drug effects/*genetics/isolation & purification, Anti-Bacterial Agents/*pharmacology, Bacterial Outer Membrane Proteins/analysis, Bacterial Proteins/*genetics/*metabolism, Carbapenems/*pharmacology, Cloning, Molecular, Cluster Analysis, DNA, Bacterial/chemistry/genetics, Disease Outbreaks, Electrophoresis, Polyacrylamide Gel, Gene Expression Profiling, Genetic Vectors, Genotype, Humans, Microbial Sensitivity Tests, Molecular Typing, Poland/epidemiology, Polymerase Chain Reaction, Sequence Analysis, DNA, Transformation, Bacterial, *beta-Lactam Resistance, beta-Lactamases/*genetics/*metabolismPathogenicity
Metabolism23284824Effect of ethanol on differential protein production and expression of potential virulence functions in the opportunistic pathogen Acinetobacter baumannii.Nwugo CC, Arivett BA, Zimbler DL, Gaddy JA, Richards AM, Actis LAPLoS One10.1371/journal.pone.00519362012Acinetobacter Infections/microbiology, Acinetobacter baumannii/*drug effects/genetics/metabolism/*pathogenicity, Adaptation, Biological, Animals, Bacterial Proteins/*metabolism, Biofilms/drug effects, Biosynthetic Pathways, Ethanol/*pharmacology, Hydrogen-Ion Concentration, Indoleacetic Acids/metabolism, Proteome, Proteomics, Reproducibility of Results, Virulence, Virulence Factors/genetics/*metabolismPathogenicity
Enzymology23439638OXA-235, a novel class D beta-lactamase involved in resistance to carbapenems in Acinetobacter baumannii.Higgins PG, Perez-Llarena FJ, Zander E, Fernandez A, Bou G, Seifert HAntimicrob Agents Chemother10.1128/AAC.02413-122013Acinetobacter Infections/drug therapy/microbiology, Acinetobacter baumannii/*drug effects/enzymology/genetics/isolation & purification, Amino Acid Sequence, Anti-Bacterial Agents/*pharmacology, Carbapenems/*pharmacology, Cephalosporins/pharmacology, *Chromosomes, Bacterial, Cloning, Molecular, DNA Transposable Elements, Escherichia coli/genetics, Humans, Isoenzymes/genetics/metabolism, Molecular Sequence Data, Mutation, *Plasmids, Recombinant Proteins/genetics/metabolism, Sequence Alignment, Sequence Analysis, DNA, Sequence Homology, Amino Acid, beta-Lactam Resistance/drug effects/*genetics, beta-Lactamases/*genetics/metabolismPathogenicity
Metabolism23456955Structure and biosynthesis of fimsbactins A-F, siderophores from Acinetobacter baumannii and Acinetobacter baylyi.Proschak A, Lubuta P, Grun P, Lohr F, Wilharm G, De Berardinis V, Bode HBChembiochem10.1002/cbic.2012007642013Acinetobacter/genetics/*metabolism, Acinetobacter baumannii/genetics/*metabolism, Bacterial Proteins/genetics/metabolism, Catechols/*chemistry, Hydroxamic Acids/*chemistry, Magnetic Resonance Spectroscopy, Mass Spectrometry, Molecular Conformation, Multigene Family, Siderophores/*biosynthesis/chemistry
Metabolism23542354A systematic quantitative proteomic examination of multidrug resistance in Acinetobacter baumannii.Chopra S, Ramkissoon K, Anderson DCJ Proteomics10.1016/j.jprot.2013.03.0082013Acinetobacter baumannii/genetics/*metabolism, Bacterial Proteins/genetics/*metabolism, Drug Resistance, Multiple, Bacterial/*physiology, Proteome/genetics/*metabolism, Proteomics/*methodsPathogenicity
Metabolism23649094H-NS plays a role in expression of Acinetobacter baumannii virulence features.Eijkelkamp BA, Stroeher UH, Hassan KA, Elbourne LD, Paulsen IT, Brown MHInfect Immun10.1128/IAI.00065-132013Acinetobacter Infections/*microbiology, Acinetobacter baumannii/genetics/*pathogenicity/physiology, Alveolar Epithelial Cells/microbiology/pathology, Amino Acid Sequence, Animals, Bacterial Adhesion, Bacterial Proteins/genetics/*metabolism, Bacterial Secretion Systems, Base Composition, Binding Sites, *Biofilms, Caenorhabditis elegans/microbiology, Cell Line, Tumor, Computational Biology/methods, DNA Transposable Elements, DNA, Bacterial/genetics, DNA-Binding Proteins/genetics/*metabolism, Fatty Acids/metabolism, Gene Expression Profiling, Gene Expression Regulation, Bacterial, Genes, Bacterial, Genetic Complementation Test, Humans, Hydrophobic and Hydrophilic Interactions, Molecular Sequence Data, Mutation, Repressor Proteins/genetics/metabolism, VirulencePathogenicity
Enzymology23742833Identification and characterisation of the putative phage-related endolysins through full genome sequence analysis in Acinetobacter baumannii ATCC 17978.Lai MJ, Soo PC, Lin NT, Hu A, Chen YJ, Chen LK, Chang KCInt J Antimicrob Agents10.1016/j.ijantimicag.2013.04.0222013Acinetobacter baumannii/drug effects/*genetics/ultrastructure/*virology, Anti-Bacterial Agents/isolation & purification/metabolism, Bacteriophages/*enzymology/*genetics, Cloning, Molecular, Endopeptidases/*genetics/isolation & purification/*metabolism, Gene Expression, Genome, Bacterial, Humans, Hydrolysis, Microscopy, Electron, Scanning, Peptidoglycan/metabolism, Sequence Analysis, DNAGenetics
Pathogenicity23908480Association of the outer membrane protein Omp33 with fitness and virulence of Acinetobacter baumannii.Smani Y, Dominguez-Herrera J, Pachon JJ Infect Dis10.1093/infdis/jit3862013Acinetobacter Infections/microbiology/mortality, Acinetobacter baumannii/*genetics/growth & development/*pathogenicity, Animals, Bacterial Adhesion/genetics, Bacterial Outer Membrane Proteins/*genetics, Biofilms, Cell Death, Cell Line, Disease Models, Animal, Epithelial Cells/metabolism/microbiology, Gene Knockout Techniques, *Genetic Fitness, Humans, Mice, Peritonitis/microbiology/mortality, Phenotype, Virulence/geneticsPhenotype
Pathogenicity23939894Contribution of efflux pumps, porins, and beta-lactamases to multidrug resistance in clinical isolates of Acinetobacter baumannii.Rumbo C, Gato E, Lopez M, Ruiz de Alegria C, Fernandez-Cuenca F, Martinez-Martinez L, Vila J, Pachon J, Cisneros JM, Rodriguez-Bano J, Pascual A, Bou G, Tomas MAntimicrob Agents Chemother10.1128/AAC.00730-132013ATP-Binding Cassette Transporters/*genetics/metabolism, Acinetobacter Infections/drug therapy/microbiology, Acinetobacter baumannii/classification/drug effects/*genetics/isolation & purification, Aminoglycosides/pharmacology, Anti-Bacterial Agents/*pharmacology, Carbapenems/pharmacology, Drug Resistance, Multiple, Bacterial/drug effects/*genetics, *Gene Expression Regulation, Bacterial, Humans, Microbial Sensitivity Tests, Phylogeny, Porins/*genetics/metabolism, Quinolones/pharmacology, Tetracyclines/pharmacology, beta-Lactamases/*genetics/metabolismPhylogeny
Transcriptome24023660Whole transcriptome analysis of Acinetobacter baumannii assessed by RNA-sequencing reveals different mRNA expression profiles in biofilm compared to planktonic cells.Rumbo-Feal S, Gomez MJ, Gayoso C, Alvarez-Fraga L, Cabral MP, Aransay AM, Rodriguez-Ezpeleta N, Fullaondo A, Valle J, Tomas M, Bou G, Poza MPLoS One10.1371/journal.pone.007296820134-Butyrolactone/analogs & derivatives/biosynthesis, Acinetobacter baumannii/*cytology/*genetics/growth & development/physiology, *Biofilms, *Gene Expression Profiling, *Gene Expression Regulation, Bacterial, Gene Knockout Techniques, Genes, Bacterial, Mutation/genetics, Plankton/cytology/*genetics, RNA, Messenger/genetics, Sequence Analysis, RNA/*methods, Transcriptome/genetics, Up-Regulation/genetics
Pathogenicity24342640Role of Acinetobacter baumannii UmuD homologs in antibiotic resistance acquired through DNA damage-induced mutagenesis.Aranda J, Lopez M, Leiva E, Magan A, Adler B, Bou G, Barbe JAntimicrob Agents Chemother10.1128/AAC.02346-132013Acinetobacter baumannii/*drug effects/genetics, Anti-Bacterial Agents/pharmacology, DNA Damage/*genetics/radiation effects, DNA-Directed DNA Polymerase/genetics, Drug Resistance, Bacterial/genetics, Mutagenesis/genetics, Rifampin/pharmacology, Streptomycin/pharmacology, Ultraviolet Rays
Pathogenicity24440358Serum resistance, gallium nitrate tolerance and extrapulmonary dissemination are linked to heme consumption in a bacteremic strain of Acinetobacter baumannii.de Leseleuc L, Harris G, KuoLee R, Xu HH, Chen WInt J Med Microbiol10.1016/j.ijmm.2013.12.0022013Acinetobacter Infections/*microbiology, Acinetobacter baumannii/drug effects/immunology/isolation & purification/*metabolism, Animals, Bacteremia/*microbiology, *Blood Bactericidal Activity, Cattle, Disease Models, Animal, Drug Resistance, Bacterial, Female, Gallium/*toxicity, Heme/*metabolism, Humans, Mice, Inbred C57BL, Pneumonia, Bacterial/complications/*microbiology, Serum/microbiologyMetabolism
Enzymology24468778Class D beta-lactamases: are they all carbapenemases?Antunes NT, Lamoureaux TL, Toth M, Stewart NK, Frase H, Vakulenko SBAntimicrob Agents Chemother10.1128/AAC.02522-132014Acinetobacter baumannii/drug effects/enzymology, Bacterial Proteins/*metabolism, Carbapenems/*pharmacology, Drug Resistance, Microbial, Escherichia coli/drug effects/enzymology, Gram-Negative Bacteria/*drug effects/enzymology, Microbial Sensitivity Tests, Pseudomonas aeruginosa/drug effects/enzymology, beta-Lactamases/*metabolismPathogenicity
Genetics24486871Proteogenomic characterization of antimicrobial resistance in extensively drug-resistant Acinetobacter baumannii DU202.Lee SY, Yun SH, Lee YG, Choi CW, Leem SH, Park EC, Kim GH, Lee JC, Kim SIJ Antimicrob Chemother10.1093/jac/dku0082014Acinetobacter baumannii/drug effects/*genetics/*metabolism, Amino Acid Sequence, Anti-Bacterial Agents/pharmacology, Bacterial Proteins/chemistry/genetics/metabolism, DNA Transposable Elements, Drug Resistance, Multiple, Bacterial/*genetics, Genome, Bacterial, Genomic Islands, *Genomics, Molecular Sequence Data, Phylogeny, *Proteomics, Sequence AlignmentPathogenicity
Pathogenicity24514427Effect of chlorine exposure on the survival and antibiotic gene expression of multidrug resistant Acinetobacter baumannii in water.Karumathil DP, Yin HB, Kollanoor-Johny A, Venkitanarayanan KInt J Environ Res Public Health10.3390/ijerph1102018442014*Acinetobacter baumannii/genetics/metabolism, *Chlorine, Disinfection, Drug Resistance, Bacterial/*genetics, Gene Expression Regulation, Bacterial/drug effects, *Water MicrobiologyMetabolism
Enzymology24566181Characterization of blaOXA-143 variants in Acinetobacter baumannii and Acinetobacter pittii.Zander E, Bonnin RA, Seifert H, Higgins PGAntimicrob Agents Chemother10.1128/AAC.02618-132014Acinetobacter/*drug effects/*enzymology, Acinetobacter baumannii/*drug effects/*enzymology, Anti-Bacterial Agents/*pharmacology, Carbapenems/*pharmacology, Microbial Sensitivity Tests, beta-Lactamases/genetics/*metabolismPathogenicity
Pathogenicity24621315Virstatin inhibits biofilm formation and motility of Acinetobacter baumannii.Nait Chabane Y, Mlouka MB, Alexandre S, Nicol M, Marti S, Pestel-Caron M, Vila J, Jouenne T, De EBMC Microbiol10.1186/1471-2180-14-622014Acinetobacter baumannii/*drug effects/*physiology, Anti-Bacterial Agents/*pharmacology, Biofilms/*drug effects, Butyrates/*pharmacology, Fimbriae, Bacterial/drug effects, Locomotion/*drug effects, Microscopy, Atomic Force, Naphthalimides/*pharmacology
Proteome24657496Ser/Thr/Tyr phosphoproteome characterization of Acinetobacter baumannii: comparison between a reference strain and a highly invasive multidrug-resistant clinical isolate.Soares NC, Spat P, Mendez JA, Nakedi K, Aranda J, Bou GJ Proteomics10.1016/j.jprot.2014.03.0092014Acinetobacter baumannii/*metabolism, Amino Acid Sequence, Chromatography, *Drug Resistance, Multiple, Bacterial, Glycolysis, Mass Spectrometry, Molecular Sequence Data, Peptides/chemistry, Phenotype, Phosphorylation, Proteome/metabolism, Proteomics, Serine/*chemistry, Tandem Mass Spectrometry, Threonine/*chemistry, Titanium/chemistry, Tyrosine/*chemistryMetabolism
Pathogenicity24709747Prophage induction and differential RecA and UmuDAb transcriptome regulation in the DNA damage responses of Acinetobacter baumannii and Acinetobacter baylyi.Hare JM, Ferrell JC, Witkowski TA, Grice ANPLoS One10.1371/journal.pone.00938612014Acinetobacter/*genetics, Acinetobacter baumannii/*genetics, Bacterial Proteins/*genetics/metabolism, DNA Damage/drug effects/*genetics, DNA-Binding Proteins/*genetics/metabolism, Gene Expression Regulation, Bacterial/drug effects/*genetics, Mitomycin/pharmacology, Rec A Recombinases/*genetics/metabolism, Transcriptome/drug effects/*genetics, Virus Activation/drug effects/*geneticsMetabolism
Genetics24833435Insertion sequence transposition determines imipenem resistance in Acinetobacter baumannii.Kuo HY, Chang KC, Liu CC, Tang CY, Peng JH, Lu CW, Tu CC, Liou MLMicrob Drug Resist10.1089/mdr.2014.00042014Acinetobacter Infections/drug therapy/microbiology, Acinetobacter baumannii/drug effects/enzymology/*genetics, Anti-Bacterial Agents/*pharmacology, Bacterial Proteins/*genetics/metabolism, Base Sequence, *DNA Transposable Elements, Electrophoresis, Gel, Pulsed-Field, *Gene Expression Regulation, Bacterial, Genotype, Humans, Imipenem/*pharmacology, Molecular Sequence Data, Mutagenesis, Insertional, Phenotype, Plasmids/chemistry/metabolism, RNA, Ribosomal, 16S/genetics, beta-Lactamases/*genetics/metabolismEnzymology
Pathogenicity24879663Characterization of plasmids carrying the blaOXA-24/40 carbapenemase gene and the genes encoding the AbkA/AbkB proteins of a toxin/antitoxin system.Mosqueda N, Gato E, Roca I, Lopez M, de Alegria CR, Fernandez Cuenca F, Martinez-Martinez L, Pachon J, Cisneros JM, Rodriguez-Bano J, Pascual A, Vila J, Bou G, Tomas MJ Antimicrob Chemother10.1093/jac/dku1792014Acinetobacter Infections/microbiology, Acinetobacter baumannii/drug effects/*genetics/isolation & purification, Anti-Bacterial Agents/pharmacology, Antitoxins/*genetics, Bacterial Toxins/*genetics, Geography, Microbial Sensitivity Tests, Molecular Sequence Data, Open Reading Frames, Plasmids/*genetics, beta-Lactamases/*geneticsGenetics
Metabolism24885279Role of the BaeSR two-component system in the regulation of Acinetobacter baumannii adeAB genes and its correlation with tigecycline susceptibility.Lin MF, Lin YY, Yeh HW, Lan CYBMC Microbiol10.1186/1471-2180-14-1192014Acinetobacter baumannii/*drug effects/genetics/physiology, Anti-Bacterial Agents/*pharmacology, Bacterial Proteins/*metabolism, Drug Resistance, Bacterial, Gene Expression Regulation, Bacterial, Membrane Transport Proteins/*metabolism, Microbial Sensitivity Tests, Minocycline/*analogs & derivatives/pharmacology, Osmotic Pressure, Protein Kinases/*metabolism, Stress, Physiological, Tigecycline, Trans-Activators/*metabolismPathogenicity
Metabolism24895306Genome-wide identification of Acinetobacter baumannii genes necessary for persistence in the lung.Wang N, Ozer EA, Mandel MJ, Hauser ARmBio10.1128/mBio.01163-142014Acinetobacter Infections/*microbiology, Acinetobacter baumannii/*genetics/metabolism, Amino Acids/metabolism, Animals, Bacterial Capsules/metabolism, DNA Transposable Elements, Disease Models, Animal, Female, Gene Library, *Genes, Bacterial, Genome, Bacterial, Genome-Wide Association Study, High-Throughput Nucleotide Sequencing, Lipopolysaccharides/biosynthesis, Mice, Mutation, Nucleotides/metabolism, Pneumonia/*microbiology, Reproducibility of Results, Stress, Physiological, Virulence/genetics, Virulence Factors/geneticsGenetics
Enzymology24910020CpaA a novel protease from Acinetobacter baumannii clinical isolates deregulates blood coagulation.Tilley D, Law R, Warren S, Samis JA, Kumar AFEMS Microbiol Lett10.1111/1574-6968.124962014Acinetobacter Infections/*blood/microbiology, Acinetobacter baumannii/*enzymology/isolation & purification, Bacterial Proteins/chemistry/*physiology, Blood Coagulation, Catalytic Domain, Conserved Sequence, Fibrinogen/chemistry, Humans, Metalloendopeptidases/chemistry/*physiology, Partial Thromboplastin Time, Proteolysis, Sequence Analysis, ProteinPathogenicity
Pathogenicity25000585Impact of Acinetobacter baumannii superoxide dismutase on motility, virulence, oxidative stress resistance and susceptibility to antibiotics.Heindorf M, Kadari M, Heider C, Skiebe E, Wilharm GPLoS One10.1371/journal.pone.01010332014Acinetobacter baumannii/*drug effects/*enzymology/metabolism/pathogenicity, Animals, Anti-Bacterial Agents/*pharmacology, *Drug Resistance, Bacterial, Enzyme Activation/drug effects, Lepidoptera/microbiology, *Movement/drug effects, Mutation, *Oxidative Stress/drug effects, Reactive Oxygen Species/metabolism, Superoxide Dismutase/genetics/*metabolismMetabolism
Pathogenicity25136007Triclosan can select for an AdeIJK-overexpressing mutant of Acinetobacter baumannii ATCC 17978 that displays reduced susceptibility to multiple antibiotics.Fernando DM, Xu W, Loewen PC, Zhanel GG, Kumar AAntimicrob Agents Chemother10.1128/AAC.03074-142014Acinetobacter Infections/drug therapy/microbiology, Acinetobacter baumannii/drug effects/enzymology/*genetics, Anti-Bacterial Agents/*pharmacology, Bacterial Proteins/biosynthesis/*genetics, Base Sequence, Drug Resistance, Multiple, Bacterial/genetics, Enoyl-(Acyl-Carrier-Protein) Reductase (NADH)/genetics, Fatty Acid Synthase, Type II/genetics, Fatty Acid Synthesis Inhibitors/pharmacology, Gene Expression Regulation, Bacterial/drug effects, Genome, Bacterial/genetics, Membrane Transport Proteins/biosynthesis/*genetics, Microbial Sensitivity Tests, Selection, Genetic/*drug effects/genetics, Sequence Analysis, DNA, Triclosan/*pharmacologyEnzymology
Genetics25164683Whole-genome sequence analysis of the naturally competent Acinetobacter baumannii clinical isolate A118.Traglia GM, Chua K, Centron D, Tolmasky ME, Ramirez MSGenome Biol Evol10.1093/gbe/evu1762014Acinetobacter Infections/microbiology, Acinetobacter baumannii/drug effects/*genetics, Anti-Bacterial Agents/pharmacology, Base Sequence, *Genome, Bacterial, Genomics, Humans, Molecular Sequence Data, Mutation, Sequence Analysis, DNATranscriptome
Metabolism25260865Transcriptome profiling in imipenem-selected Acinetobacter baumannii.Chang KC, Kuo HY, Tang CY, Chang CW, Lu CW, Liu CC, Lin HR, Chen KH, Liou MLBMC Genomics10.1186/1471-2164-15-8152014Acinetobacter baumannii/drug effects/*genetics/metabolism, Anti-Bacterial Agents/analysis/metabolism/*pharmacology, Bacterial Proteins/metabolism, Biofilms/drug effects, Chromatography, High Pressure Liquid, Gene Expression Profiling, *Genes, Bacterial, Hydrolysis, Imipenem/analysis/metabolism/*pharmacology, Microbial Sensitivity Tests, Tandem Mass Spectrometry, Transcriptome, beta-Lactamases/metabolismTranscriptome
Enzymology25896698Therapeutic efficacy of lysophosphatidylcholine in severe infections caused by Acinetobacter baumannii.Smani Y, Dominguez-Herrera J, Ibanez-Martinez J, Pachon JAntimicrob Agents Chemother10.1128/AAC.04986-142015Acinetobacter Infections/*drug therapy/microbiology/mortality, *Acinetobacter baumannii, Animals, Colony Count, Microbial, Cytokines/blood, Drug Resistance, Bacterial, Female, Lung/microbiology, Lysophosphatidylcholines/blood/pharmacokinetics/*therapeutic use, Mice, Mice, Inbred C57BL, Microbial Sensitivity Tests, Pneumonia/microbiology, Sepsis/microbiology, Spleen/microbiology
Metabolism26047954Identification of genes essential for pellicle formation in Acinetobacter baumannii.Giles SK, Stroeher UH, Eijkelkamp BA, Brown MHBMC Microbiol10.1186/s12866-015-0440-62015Acinetobacter baumannii/*physiology, Bacterial Proteins/*genetics/*metabolism, Biofilms/*growth & development, Cyclic AMP/metabolism, Gene Expression Profiling, Gene Expression Regulation, Bacterial, Genes, Essential, Hydrophobic and Hydrophilic Interactions, Mutagenesis, Insertional, Operon, Quantitative Trait Loci
Pathogenicity26055688Distribution of different efflux pump genes in clinical isolates of multidrug-resistant Acinetobacter baumannii and their correlation with antimicrobial resistance.Lin MF, Lin YY, Tu CC, Lan CYJ Microbiol Immunol Infect10.1016/j.jmii.2015.04.0042015Acinetobacter Infections/*microbiology, Acinetobacter baumannii/*drug effects/*genetics/metabolism, Anti-Bacterial Agents/pharmacokinetics/*pharmacology, Bacterial Proteins/*genetics/metabolism, DNA, Bacterial/analysis, Drug Resistance, Multiple, Bacterial, Genes, Bacterial, Humans, Membrane Proteins/genetics, Membrane Transport Proteins/*genetics/metabolism, Microbial Sensitivity Tests, RNA, Bacterial/analysisMetabolism
Genetics26057991Structure of the neutral capsular polysaccharide of Acinetobacter baumannii NIPH146 that carries the KL37 capsule gene cluster.Arbatsky NP, Shneider MM, Kenyon JJ, Shashkov AS, Popova AV, Miroshnikov KA, Volozhantsev NV, Knirel YACarbohydr Res10.1016/j.carres.2015.05.0032015Acinetobacter baumannii/*chemistry/*genetics, Bacterial Capsules/*chemistry/*genetics, Carbohydrate Sequence, Genetic Loci/genetics, Molecular Sequence Data, Polysaccharides, Bacterial/*chemistry
26213382Optimisation of the Caenorhabditis elegans model for studying the pathogenesis of opportunistic Acinetobacter baumannii.Vallejo JA, Beceiro A, Rumbo-Feal S, Rodriguez-Palero MJ, Russo TA, Bou GInt J Antimicrob Agents10.1016/j.ijantimicag.2015.05.0212015
Pathogenicity26401654Differential Role of the T6SS in Acinetobacter baumannii Virulence.Repizo GD, Gagne S, Foucault-Grunenwald ML, Borges V, Charpentier X, Limansky AS, Gomes JP, Viale AM, Salcedo SPPLoS One10.1371/journal.pone.01382652015Acinetobacter Infections/microbiology, Acinetobacter baumannii/*pathogenicity/*physiology, Animals, Biofilms, Biomass, Gene Expression Regulation, Bacterial, Gene Order, Genetic Complementation Test, Genetic Loci, Humans, Microbial Interactions, Molecular Sequence Data, Moths/microbiology, Mutation, Phenotype, Type VI Secretion Systems/*genetics, Virulence/geneticsGenetics
Metabolism26420036Rapid and sensitive detection of carbapenemase activity in Acinetobacter baumannii using superficially porous liquid chromatography-tandem mass spectrometry.Lin HR, Hu A, Lai MJ, Chiang CW, Liao CC, Chang KCJ Microbiol Immunol Infect10.1016/j.jmii.2015.08.0012015Acinetobacter baumannii/*drug effects/isolation & purification/metabolism, Anti-Bacterial Agents/*metabolism, Bacterial Proteins/*metabolism, Chromatography, Liquid/*methods, Drug Resistance, Multiple, Bacterial, Humans, Imipenem/*metabolism, Meropenem, Tandem Mass Spectrometry/*methods, Thienamycins/*metabolism, beta-Lactamases/*metabolismPathogenicity
Metabolism26668261Acinetobacter baumannii Is Dependent on the Type II Secretion System and Its Substrate LipA for Lipid Utilization and In Vivo Fitness.Johnson TL, Waack U, Smith S, Mobley H, Sandkvist MJ Bacteriol10.1128/JB.00622-152015Acinetobacter Infections/*microbiology, Acinetobacter baumannii/chemistry/*enzymology/genetics/metabolism, Amino Acid Sequence, Animals, Bacterial Proteins/chemistry/genetics/*metabolism, Female, Humans, *Lipid Metabolism, Mice, Inbred CBA, Molecular Sequence Data, Sequence Alignment, Type II Secretion Systems/chemistry/genetics/*metabolismPathogenicity
Enzymology27001819Effects of Saline, an Ambient Acidic Environment, and Sodium Salicylate on OXA-Mediated Carbapenem Resistance in Acinetobacter baumannii.Zander E, Seifert H, Higgins PGAntimicrob Agents Chemother10.1128/AAC.03010-152016Acinetobacter baumannii/*drug effects/*enzymology/genetics, Anti-Bacterial Agents/*pharmacology, Carbapenems/*pharmacology, Drug Resistance, Bacterial/genetics, Hydrogen-Ion Concentration, Microbial Sensitivity Tests, Reverse Transcriptase Polymerase Chain Reaction, Sodium Chloride/*pharmacology, Sodium Salicylate/*pharmacology, beta-Lactamases/*metabolismPathogenicity
27005666Ciprofloxacin-Induced Antibacterial Activity Is Atteneuated by Pretreatment with Antioxidant Agents.Masadeh MM, Alzoubi KH, Al-Azzam SI, Khabour OF, Al-Buhairan AMPathogens10.3390/pathogens50100282016
Metabolism27067318Mutations Decreasing Intrinsic beta-Lactam Resistance Are Linked to Cell Division in the Nosocomial Pathogen Acinetobacter baumannii.Knight D, Dimitrova DD, Rudin SD, Bonomo RA, Rather PNAntimicrob Agents Chemother10.1128/AAC.00361-162016Acinetobacter baumannii/drug effects/enzymology/*genetics/growth & development, Ampicillin/pharmacology, Anti-Bacterial Agents/pharmacology, Bacterial Proteins/genetics/metabolism, Cefotaxime/pharmacology, Ceftriaxone/pharmacology, Cell Division/drug effects/*genetics, *DNA Transposable Elements, Gene Expression, *Genes, Bacterial, Imipenem/pharmacology, Membrane Transport Proteins/genetics/metabolism, Microbial Sensitivity Tests, *Mutagenesis, Insertional, Phenotype, Plasmids/chemistry/metabolism, beta-Lactam Resistance/*genetics, beta-Lactamases/genetics/metabolismPathogenicity
Metabolism27222042Proteomic characterization of Nalpha- and Nepsilon-acetylation in Acinetobacter baumannii.Kentache T, Jouenne T, De E, Hardouin JJ Proteomics10.1016/j.jprot.2016.05.0212016Acetylation, Acinetobacter baumannii/*metabolism, Adaptation, Physiological, Bacterial Proteins/*metabolism, Biofilms/growth & development, Drug Resistance, Protein Processing, Post-Translational/*physiology, Proteomics/*methods, Virulence
Phenotype27399903Characterization of a highly virulent and antimicrobial-resistant Acinetobacter baumannii strain isolated from diseased chicks in China.Liu D, Liu ZS, Hu P, Hui Q, Fu BQ, Lu SY, Li YS, Zou DY, Li ZH, Yan DM, Ding YX, Zhang YY, Zhou Y, Liu NN, Ren HLMicrobiol Immunol10.1111/1348-0421.124002016Acinetobacter Infections/*veterinary, Acinetobacter baumannii/*drug effects/genetics/isolation & purification/ultrastructure, Animals, Anti-Bacterial Agents/*pharmacology, China, *Drug Resistance, Bacterial, Microbial Sensitivity Tests, Phenotype, Poultry Diseases/diagnosis/*microbiology/mortality, VirulenceEnzymology
Pathogenicity27469573Design of an anti-adhesive surface by a pilicide strategy.Reffuveille F, Nicol M, De E, Thebault PColloids Surf B Biointerfaces10.1016/j.colsurfb.2016.07.0372016Acinetobacter baumannii/*drug effects, Anti-Bacterial Agents/chemistry/*pharmacology, Bacterial Adhesion/*drug effects, Biofilms/drug effects/*growth & development, Butyrates/pharmacology, *Drug Design, Fimbriae, Bacterial/*drug effects, Hydrophobic and Hydrophilic Interactions, Locomotion/drug effects, Naphthalimides/pharmacology, Propylamines/chemistry, Silanes/chemistry, Surface Properties, Virulence/drug effects
Pathogenicity27479925Evaluation of the ability of Acinetobacter baumannii to form biofilms on six different biomedical relevant surfaces.Greene C, Wu J, Rickard AH, Xi CLett Appl Microbiol10.1111/lam.126272016Acinetobacter Infections/*microbiology, Acinetobacter baumannii/*growth & development/*metabolism, Biofilms/*growth & development, Ceramics, Colony Count, Microbial, Equipment and Supplies/*microbiology, Glass, Hospitals, Humans, Microscopy, Confocal, Opportunistic Infections/*microbiology, Polymers, Polypropylenes, Rubber, Stainless Steel, Surface PropertiesMetabolism
Metabolism27713027The secretome of Acinetobacter baumannii ATCC 17978 type II secretion system reveals a novel plasmid encoded phospholipase that could be implicated in lung colonization.Elhosseiny NM, El-Tayeb OM, Yassin AS, Lory S, Attia ASInt J Med Microbiol10.1016/j.ijmm.2016.09.0062016Acinetobacter Infections/*microbiology/pathology, Acinetobacter baumannii/genetics/*metabolism, Animals, Disease Models, Animal, Female, Gene Deletion, Gene Order, Genes, Bacterial, Genetic Complementation Test, Lung/*microbiology, Mice, Mice, Inbred C57BL, Phospholipases/*metabolism, Plasmids, Pneumonia, Bacterial/*microbiology/pathology, Protein Transport, Pseudomonas aeruginosa/genetics, Type II Secretion Systems/genetics/*metabolism, Virulence Factors/*metabolism
27847502The Effect of Colistin Resistance-Associated Mutations on the Fitness of Acinetobacter baumannii.Mu X, Wang N, Li X, Shi K, Zhou Z, Yu Y, Hua XFront Microbiol10.3389/fmicb.2016.017152016
Pathogenicity27908580Antimicrobial activity of novel 4H-4-oxoquinolizine compounds against extensively drug-resistant Acinetobacter baumannii strains.Na SH, Jeon H, Kim YJ, Kwon HI, Selasi GN, Nicholas A, Yun CS, Lee SH, Lee JCInt J Antimicrob Agents10.1016/j.ijantimicag.2016.10.0082016Acinetobacter baumannii/*drug effects, Anti-Bacterial Agents/chemistry/*pharmacology/toxicity, Cell Line, Cell Survival/drug effects, Drug Evaluation, Preclinical, High-Throughput Screening Assays, Humans, Microbial Sensitivity Tests, Quinolizines/chemistry/*pharmacology/toxicity
Phylogeny27917170Isolation and Characterization of Acinetobacter baumannii Recovered from Campylobacter Selective Medium.Fernando DM, Khan IU, Patidar R, Lapen DR, Talbot G, Topp E, Kumar AFront Microbiol10.3389/fmicb.2016.018712016
Genetics27939676Multi-omics approach to study global changes in a triclosan-resistant mutant strain of Acinetobacter baumannii ATCC 17978.Fernando DM, Chong P, Singh M, Spicer V, Unger M, Loewen PC, Westmacott G, Kumar AInt J Antimicrob Agents10.1016/j.ijantimicag.2016.10.0142016Acinetobacter baumannii/*drug effects, Anti-Infective Agents, Local/*pharmacology, *Drug Resistance, Bacterial, *Gene Expression Profiling, *Genome, Bacterial, Lipid Metabolism, Metabolic Networks and Pathways/genetics, Mutation, Proteome/*analysis, Sequence Analysis, DNA, Triclosan/*pharmacologyTranscriptome
Phylogeny28207864Characterisation and genome sequence of the lytic Acinetobacter baumannii bacteriophage vB_AbaS_Loki.Turner D, Wand ME, Briers Y, Lavigne R, Sutton JM, Reynolds DMPLoS One10.1371/journal.pone.01723032017Acinetobacter Infections/*microbiology, Acinetobacter baumannii/isolation & purification/*virology, Bacteriophages/*genetics/isolation & purification/*pathogenicity, DNA, Viral/*genetics, *Genome, Viral, Humans, Phylogeny, Sequence Analysis, DNA, Viral Plaque Assay, Viral Proteins/*genetics, Virus AttachmentGenetics
Pathogenicity28284195Zinc stress induces copper depletion in Acinetobacter baumannii.Hassan KA, Pederick VG, Elbourne LD, Paulsen IT, Paton JC, McDevitt CA, Eijkelkamp BABMC Microbiol10.1186/s12866-017-0965-y2017Acinetobacter Infections/microbiology, Acinetobacter baumannii/*drug effects/genetics/growth & development, Anti-Bacterial Agents/pharmacology, Biological Transport, Active, Copper/*pharmacology, Drug Resistance, Multiple, Bacterial/drug effects, Humans, Membrane Transport Proteins/drug effects, Oxidative Stress/drug effects, Phenotype, Reactive Oxygen Species/pharmacology, *Stress, Physiological, THP-1 Cells/drug effects, Zinc/*pharmacologyPhenotype
Pathogenicity28421168Contribution of the A. baumannii A1S_0114 Gene to the Interaction with Eukaryotic Cells and Virulence.Rumbo-Feal S, Perez A, Ramelot TA, Alvarez-Fraga L, Vallejo JA, Beceiro A, Ohneck EJ, Arivett BA, Merino M, Fiester SE, Kennedy MA, Actis LA, Bou G, Poza MFront Cell Infect Microbiol10.3389/fcimb.2017.001082017Acinetobacter Infections/microbiology/pathology, Acinetobacter baumannii/*genetics/*pathogenicity/physiology, Adhesins, Bacterial/genetics, Animals, *Bacterial Adhesion, Biofilms/growth & development, Caenorhabditis elegans, Cell Line, Disease Models, Animal, Epithelial Cells/*microbiology, Female, Gene Deletion, *Host-Pathogen Interactions, Humans, Lepidoptera, Mice, Inbred BALB C, Microscopy, Virulence, Virulence Factors/*genetics
Pathogenicity28427132[Influences of abaR gene on biofilm formation of Acinetobacter baumannii].Guo HN, Xiang JZhonghua Shao Shang Za Zhi10.3760/cma.j.issn.1009-2587.2017.04.00320174-Butyrolactone/analogs & derivatives, Acinetobacter Infections/drug therapy/*microbiology, Acinetobacter baumannii/drug effects/*genetics/*isolation & purification, *Biofilms, Burns/*microbiology, China, Drug Resistance, Bacterial, Genes, Bacterial, HumansEnzymology
Metabolism28436748Disruption of tetR type regulator adeN by mobile genetic element confers elevated virulence in Acinetobacter baumannii.Saranathan R, Pagal S, Sawant AR, Tomar A, Madhangi M, Sah S, Satti A, Arunkumar KP, Prashanth KVirulence10.1080/21505594.2017.13222402017Acinetobacter Infections/*microbiology, Acinetobacter baumannii/*genetics/growth & development/metabolism/*pathogenicity, Bacterial Proteins/genetics/*metabolism, Gene Expression Regulation, Bacterial, Humans, Interspersed Repetitive Sequences, *Mutagenesis, Insertional, Trans-Activators/genetics/*metabolism, VirulencePathogenicity
Pathogenicity28507065Mutations in the beta-Subunit of the RNA Polymerase Impair the Surface-Associated Motility and Virulence of Acinetobacter baumannii.Perez-Varela M, Corral J, Vallejo JA, Rumbo-Feal S, Bou G, Aranda J, Barbe JInfect Immun10.1128/IAI.00327-172017Acinetobacter Infections/microbiology, Acinetobacter baumannii/enzymology/*genetics/*pathogenicity/physiology, Amino Acid Substitution, Animals, Bacterial Proteins/genetics, Caenorhabditis elegans/microbiology, Cross Infection/microbiology, DNA-Directed RNA Polymerases/chemistry/*genetics/*metabolism, Down-Regulation, Drug Resistance, Multiple, Bacterial, Gene Expression Profiling, Gene Knockout Techniques, Humans, Membrane Transport Proteins/genetics, *Point Mutation, Virulence/geneticsEnzymology
Pathogenicity28536672Response to Bile Salts in Clinical Strains of Acinetobacter baumannii Lacking the AdeABC Efflux Pump: Virulence Associated with Quorum Sensing.Lopez M, Blasco L, Gato E, Perez A, Fernandez-Garcia L, Martinez-Martinez L, Fernandez-Cuenca F, Rodriguez-Bano J, Pascual A, Bou G, Tomas MFront Cell Infect Microbiol10.3389/fcimb.2017.001432017Acinetobacter baumannii/*drug effects/*genetics/growth & development/pathogenicity, Anti-Bacterial Agents/pharmacology, Bacterial Proteins/genetics, Bile Acids and Salts/*pharmacology, Biofilms/drug effects, Drug Resistance, Multiple, Bacterial, Drug Tolerance, Gastrointestinal Tract/microbiology, Gene Expression Regulation, Bacterial, Genes, Bacterial/genetics, Humans, Microbial Sensitivity Tests, Quorum Sensing/*drug effects/genetics, Type VI Secretion Systems/drug effects, Virulence/*drug effects/genetics, Virulence Factors/genetics
Pathogenicity28674047Subinhibitory Concentrations of Trimethoprim and Sulfamethoxazole Prevent Biofilm Formation by Acinetobacter baumannii through Inhibition of Csu Pilus Expression.Moon KH, Weber BS, Feldman MFAntimicrob Agents Chemother10.1128/AAC.00778-172017Acinetobacter Infections/*drug therapy/metabolism, Acinetobacter baumannii/*drug effects/metabolism, Anti-Bacterial Agents/pharmacology, Bacterial Proteins/*metabolism, Biofilms/*drug effects, Drug Resistance, Multiple, Bacterial/drug effects, Humans, Sulfamethoxazole/*pharmacology, Trimethoprim/*pharmacology, Virulence Factors/metabolismMetabolism
Metabolism28714256A1S_2811, a CheA/Y-like hybrid two-component regulator from Acinetobacter baumannii ATCC17978, is involved in surface motility and biofilm formation in this bacterium.Chen R, Lv R, Xiao L, Wang M, Du Z, Tan Y, Cui Y, Yan Y, Luo Y, Yang R, Song YMicrobiologyopen10.1002/mbo3.5102017Acinetobacter baumannii/*physiology/ultrastructure, Bacterial Proteins/genetics/metabolism, *Biofilms, Gene Deletion, Gene Expression Profiling, Gene Expression Regulation, Bacterial, Gene Knockout Techniques, Gene Order, Histidine Kinase/chemistry/*genetics/*metabolism, Lactones/metabolism, Operon, Phenotype, *Quorum SensingPhenotype
Pathogenicity28733283Osmotic Compounds Enhance Antibiotic Efficacy against Acinetobacter baumannii Biofilm Communities.Falghoush A, Beyenal H, Besser TE, Omsland A, Call DRAppl Environ Microbiol10.1128/AEM.01297-172017Acinetobacter baumannii/*drug effects/growth & development/physiology, Anti-Bacterial Agents/*pharmacology, Biofilms/*drug effects, Ciprofloxacin/pharmacology, Microbial Sensitivity Tests, Osmosis, Polyethylene Glycols/pharmacology, Polysaccharides/pharmacology, Sucrose/pharmacology, Tobramycin/pharmacology
Pathogenicity28763494Global assessment of small RNAs reveals a non-coding transcript involved in biofilm formation and attachment in Acinetobacter baumannii ATCC 17978.Alvarez-Fraga L, Rumbo-Feal S, Perez A, Gomez MJ, Gayoso C, Vallejo JA, Ohneck EJ, Valle J, Actis LA, Beceiro A, Bou G, Poza MPLoS One10.1371/journal.pone.01820842017A549 Cells, Acinetobacter baumannii/*genetics/physiology, *Biofilms, Cell Line, Tumor, DNA, Complementary/genetics, *Gene Expression Profiling, Gene Expression Regulation, Bacterial, Humans, Microscopy, Electron, Scanning, RNA, Bacterial/genetics, RNA, Small Untranslated/*genetics, Virulence
Metabolism28866739Effect of Sodium Chloride on Surface-Associated Motility of Acinetobacter baumannii and the Role of AdeRS Two-Component System.De Silva PM, Kumar AJ Membr Biol10.1007/s00232-017-9985-72017Acinetobacter baumannii/*drug effects/*metabolism, Anti-Bacterial Agents/*pharmacology, Bacterial Proteins/*metabolism, Biofilms/drug effects, Membrane Transport Proteins/*metabolism, Sodium Chloride/*pharmacologyPathogenicity
Pathogenicity28981866Outer membrane protein A contributes to antimicrobial resistance of Acinetobacter baumannii through the OmpA-like domain.Kwon HI, Kim S, Oh MH, Na SH, Kim YJ, Jeon YH, Lee JCJ Antimicrob Chemother10.1093/jac/dkx2572017Acinetobacter Infections/microbiology, Acinetobacter baumannii/*drug effects/genetics/pathogenicity, Anti-Bacterial Agents/*pharmacology, Bacterial Outer Membrane Proteins/*chemistry/genetics/*metabolism, Colistin/pharmacology, *Drug Resistance, Multiple, Bacterial, Gene Deletion, Gene Expression Regulation, Bacterial, Humans, Imipenem/pharmacology, Microbial Sensitivity Tests, Mutation/drug effects, Protein Domains, Trimethoprim/pharmacologyMetabolism
Pathogenicity29061747Effect of Incubation Temperature on Antibiotic Resistance and Virulence Factors of Acinetobacter baumannii ATCC 17978.De Silva PM, Chong P, Fernando DM, Westmacott G, Kumar AAntimicrob Agents Chemother10.1128/AAC.01514-172017Acinetobacter baumannii/*drug effects/pathogenicity/*physiology, Adaptation, Physiological/*physiology, Animals, Anti-Bacterial Agents/*pharmacology, Aztreonam/*pharmacology, Biofilms/growth & development, Gene Expression Regulation, Bacterial, Microbial Sensitivity Tests, Moths/microbiology, *Temperature, Trimethoprim, Sulfamethoxazole Drug Combination/*pharmacology, Virulence Factors
29075243Acinetobacter baumannii Virulence Traits: A Comparative Study of a Novel Sequence Type with Other Italian Endemic International Clones.Ambrosi C, Scribano D, Aleandri M, Zagaglia C, Di Francesco L, Putignani L, Palamara ATFront Microbiol10.3389/fmicb.2017.019772017
29081676Possible involvement of ROS generation in vorinostat pretreatment induced enhancement of the antibacterial activity of ciprofloxacin.Masadeh MM, Alzoubi KH, Al-Azzam SI, Al-Buhairan AMClin Pharmacol10.2147/CPAA.S1484482017
29163381Functional Characterization of Acinetobacter baumannii Lacking the RNA Chaperone Hfq.Kuo HY, Chao HH, Liao PC, Hsu L, Chang KC, Tung CH, Chen CH, Liou MLFront Microbiol10.3389/fmicb.2017.020682017
Pathogenicity29320462Unsaturated Fatty Acids Affect Quorum Sensing Communication System and Inhibit Motility and Biofilm Formation of Acinetobacter baumannii.Nicol M, Alexandre S, Luizet JB, Skogman M, Jouenne T, Salcedo SP, De EInt J Mol Sci10.3390/ijms190102142018Acinetobacter baumannii/*physiology, Acyl-Butyrolactones/metabolism, Biofilms/*drug effects, Fatty Acids, Monounsaturated/pharmacology, Fatty Acids, Unsaturated/*pharmacology, Microscopy, Atomic Force, Quorum Sensing/*drug effectsMetabolism
Metabolism29334313Pneumonia infection in mice reveals the involvement of the feoA gene in the pathogenesis of Acinetobacter baumannii.Alvarez-Fraga L, Vazquez-Ucha JC, Martinez-Guitian M, Vallejo JA, Bou G, Beceiro A, Poza MVirulence10.1080/21505594.2017.14204512018A549 Cells, Acinetobacter Infections/*physiopathology, Acinetobacter baumannii/genetics/*pathogenicity, Animals, Bacterial Adhesion, Biofilms/growth & development, Cation Transport Proteins/genetics/*metabolism, Disease Models, Animal, Epithelial Cells/microbiology, Gene Expression Profiling, Gene Knockout Techniques, Humans, Lung/microbiology, Mice, Pneumonia, Bacterial/*physiopathology, Virulence Factors/genetics/*metabolismPathogenicity
Pathogenicity29463538Relationship between Tolerance and Persistence Mechanisms in Acinetobacter baumannii Strains with AbkAB Toxin-Antitoxin System.Fernandez-Garcia L, Fernandez-Cuenca F, Blasco L, Lopez-Rojas R, Ambroa A, Lopez M, Pascual A, Bou G, Tomas MAntimicrob Agents Chemother10.1128/AAC.00250-182018Acinetobacter Infections/drug therapy/microbiology, Acinetobacter baumannii/*drug effects/*genetics/isolation & purification/pathogenicity, Anti-Bacterial Agents/*therapeutic use, Chlorhexidine/*therapeutic use, Drug Resistance, Multiple, Bacterial/genetics, Drug Tolerance/*genetics, Humans, Imipenem/*therapeutic use, Microbial Sensitivity Tests, Plasmids/genetics, Toxin-Antitoxin Systems/*genetics, beta-Lactamases/*geneticsEnzymology
Metabolism29661860Substrate Specificities and Efflux Efficiencies of RND Efflux Pumps of Acinetobacter baumannii.Leus IV, Weeks JW, Bonifay V, Smith L, Richardson S, Zgurskaya HIJ Bacteriol10.1128/JB.00049-182018Acinetobacter baumannii/drug effects/genetics/*metabolism, Anti-Bacterial Agents/metabolism/pharmacology, Bacterial Proteins/genetics/*metabolism, Gene Expression Regulation, Bacterial, Membrane Transport Proteins/genetics/*metabolism, Microbial Sensitivity Tests, Substrate SpecificityPathogenicity
Transcriptome29750823Resistance to pentamidine is mediated by AdeAB, regulated by AdeRS, and influenced by growth conditions in Acinetobacter baumannii ATCC 17978.Adams FG, Stroeher UH, Hassan KA, Marri S, Brown MHPLoS One10.1371/journal.pone.01974122018Acinetobacter Infections/*drug therapy, Acinetobacter baumannii/*drug effects/genetics, Anti-Bacterial Agents/*pharmacology, Bacterial Proteins/genetics/*physiology, Carbon/chemistry, Chelating Agents/chemistry, Computational Biology, Drug Resistance, Multiple, Bacterial/*genetics, Gene Deletion, Gene Expression Regulation, Bacterial, Genetic Complementation Test, Iron/chemistry, Membrane Transport Proteins/genetics/*physiology, Microbial Sensitivity Tests, Mutation, Oligonucleotide Array Sequence Analysis, Oxidation-Reduction, Pentamidine/*pharmacology, Phenotype, Sequence Analysis, RNA, TranscriptomePhenotype
29875743Trans-Cinnamaldehyde and Eugenol Increase Acinetobacter baumannii Sensitivity to Beta-Lactam Antibiotics.Karumathil DP, Nair MS, Gaffney J, Kollanoor-Johny A, Venkitanarayanan KFront Microbiol10.3389/fmicb.2018.010112018
Pathogenicity29891547A Light-Regulated Type I Pilus Contributes to Acinetobacter baumannii Biofilm, Motility, and Virulence Functions.Wood CR, Ohneck EJ, Edelmann RE, Actis LAInfect Immun10.1128/IAI.00442-182018A549 Cells, Acinetobacter baumannii/*genetics/*pathogenicity, Adhesins, Bacterial/genetics, Animals, Bacterial Adhesion, Bacterial Proteins/genetics, Biofilms/*growth & development, Fimbriae, Bacterial/*genetics/radiation effects, Gene Expression Profiling, *Gene Expression Regulation, Bacterial, Humans, Larva/microbiology, *Light, Moths, Operon, Temperature, Virulence/genetics
Metabolism29908915Recombinant production of A1S_0222 from Acinetobacter baumannii ATCC 17978 and confirmation of its DNA-(adenine N6)-methyltransferase activity.Blaschke U, Suwono B, Zafari S, Ebersberger I, Skiebe E, Jeffries CM, Svergun DI, Wilharm GProtein Expr Purif10.1016/j.pep.2018.06.0092018Acinetobacter baumannii/*genetics, Bacterial Proteins/*biosynthesis/genetics, DNA Methylation, Escherichia coli/genetics/metabolism, Glutathione Transferase/genetics/metabolism, Methyltransferases/*biosynthesis/genetics, Mutation, Protein Binding, Protein Conformation, Recombinant Fusion Proteins/*biosynthesis/geneticsBiotechnology
Transcriptome29986115The primary transcriptome, small RNAs and regulation of antimicrobial resistance in Acinetobacter baumannii ATCC 17978.Kroger C, MacKenzie KD, Alshabib EY, Kirzinger MWB, Suchan DM, Chao TC, Akulova V, Miranda-CasoLuengo AA, Monzon VA, Conway T, Sivasankaran SK, Hinton JCD, Hokamp K, Cameron ADSNucleic Acids Res10.1093/nar/gky6032018Acinetobacter baumannii/drug effects/*genetics, Bacterial Proteins/*genetics, Chromosome Mapping, Drug Resistance, Bacterial/*genetics, Gene Expression Profiling, Gene Expression Regulation, Bacterial, Genome, Bacterial, High-Throughput Nucleotide Sequencing, RNA, Bacterial/*genetics, Sequence Analysis, RNA/methods, Transcriptome/*geneticsGenetics
30037042Integrase-Controlled Excision of Metal-Resistance Genomic Islands in Acinetobacter baumannii.Al-Jabri Z, Zamudio R, Horvath-Papp E, Ralph JD, Al-Muharrami Z, Rajakumar K, Oggioni MRGenes (Basel)10.3390/genes90703662018
Pathogenicity30124902Peptidoglycan recycling contributes to intrinsic resistance to fosfomycin in Acinetobacter baumannii.Gil-Marques ML, Moreno-Martinez P, Costas C, Pachon J, Blazquez J, McConnell MJJ Antimicrob Chemother10.1093/jac/dky2892018Acinetobacter baumannii/*drug effects/genetics/*metabolism, Anti-Bacterial Agents/*pharmacology, Bacterial Proteins/genetics, Cell Wall/drug effects, DNA Transposable Elements, *Drug Resistance, Bacterial, Fosfomycin/*pharmacology, Microbial Sensitivity Tests, Mutation, N-Acetylmuramoyl-L-alanine Amidase/genetics, Peptidoglycan/genetics/*metabolismMetabolism
Enzymology30271754Multiple Quorum Quenching Enzymes Are Active in the Nosocomial Pathogen Acinetobacter baumannii ATCC17978.Mayer C, Muras A, Romero M, Lopez M, Tomas M, Otero AFront Cell Infect Microbiol10.3389/fcimb.2018.003102018Acinetobacter baumannii/*enzymology/genetics/growth & development/*physiology, Acyl-Butyrolactones/*metabolism, Carboxylic Ester Hydrolases/*analysis/genetics/metabolism, *Quorum SensingMetabolism
Pathogenicity30385392Distinct role of outer membrane protein A in the intrinsic resistance of Acinetobacter baumannii and Acinetobacter nosocomialis.Kwon HI, Kim S, Oh MH, Shin M, Lee JCInfect Genet Evol10.1016/j.meegid.2018.10.0222018Acinetobacter/*drug effects/*genetics, Acinetobacter Infections/drug therapy/*microbiology, Acinetobacter baumannii/*drug effects/*genetics, Anti-Bacterial Agents/*pharmacology, Bacterial Outer Membrane Proteins/*genetics, *Drug Resistance, Bacterial, Humans, Microbial Sensitivity Tests, Mutation, Trimethoprim/pharmacology
Pathogenicity30423343Anti-persister activity of squalamine against Acinetobacter baumannii.Nicol M, Mlouka MAB, Berthe T, Di Martino P, Jouenne T, Brunel JM, De EInt J Antimicrob Agents10.1016/j.ijantimicag.2018.11.0042018Acinetobacter/*drug effects, Anti-Bacterial Agents/*pharmacology, Cholestanols/pharmacology, Microbial Sensitivity Tests, Microbial Viability/*drug effects
Metabolism30578836Comparative proteomics analyses of Acinetobacter baumannii strains ATCC 17978 and AB5075 reveal the differential role of type II secretion system secretomes in lung colonization and ciprofloxacin resistance.Elhosseiny NM, Elhezawy NB, Attia ASMicrob Pathog10.1016/j.micpath.2018.12.0392018Acinetobacter Infections/*microbiology, Acinetobacter baumannii/genetics/*metabolism/*pathogenicity, Animals, Bacterial Proteins/genetics/metabolism, Biofilms/growth & development, Ciprofloxacin/*pharmacology, Disease Models, Animal, Female, Genes, Bacterial/genetics, Lung/*microbiology, Mice, Mice, Inbred C57BL, Microbial Sensitivity Tests, Mutagenesis, Insertional, *Proteomics, Type II Secretion Systems/*metabolism, Virulence
30619184Relationship Between the Quorum Network (Sensing/Quenching) and Clinical Features of Pneumonia and Bacteraemia Caused by A. baumannii.Fernandez-Garcia L, Ambroa A, Blasco L, Bleriot I, Lopez M, Alvarez-Marin R, Fernandez-Cuenca F, Martinez-Martinez L, Vila J, Rodriguez-Bano J, Garnacho-Montero J, Cisneros JM, Pascual A, Pachon J, Bou G, Smani Y, Tomas MFront Microbiol10.3389/fmicb.2018.031052018
Pathogenicity30642939Roles of Efflux Pumps from Different Superfamilies in the Surface-Associated Motility and Virulence of Acinetobacter baumannii ATCC 17978.Perez-Varela M, Corral J, Aranda J, Barbe JAntimicrob Agents Chemother10.1128/AAC.02190-182019Acinetobacter baumannii/*drug effects/genetics/*pathogenicity, Animals, Anti-Bacterial Agents/*pharmacology, Biological Transport/genetics, Cross Infection/microbiology, Drug Resistance, Multiple, Bacterial/*genetics, Gene Expression Regulation, Bacterial, Humans, Membrane Transport Proteins/genetics/*metabolism, Microbial Sensitivity Tests, Moths/microbiologyMetabolism
30666237Colistin Resistant A. baumannii: Genomic and Transcriptomic Traits Acquired Under Colistin Therapy.Cafiso V, Stracquadanio S, Lo Verde F, Gabriele G, Mezzatesta ML, Caio C, Pigola G, Ferro A, Stefani SFront Microbiol10.3389/fmicb.2018.031952019
30746493Metabolic Responses to Polymyxin Treatment in Acinetobacter baumannii ATCC 19606: Integrating Transcriptomics and Metabolomics with Genome-Scale Metabolic Modeling.Zhu Y, Zhao J, Maifiah MHM, Velkov T, Schreiber F, Li JmSystems10.1128/mSystems.00157-182019
Genetics30787115MITE Aba12 , a Novel Mobile Miniature Inverted-Repeat Transposable Element Identified in Acinetobacter baumannii ATCC 17978 and Its Prevalence across the Moraxellaceae Family.Adams FG, Brown MHmSphere10.1128/mSphereDirect.00028-192019Acinetobacter baumannii/*genetics, *DNA Transposable Elements, Evolution, Molecular, *Genome, Bacterial, *Inverted Repeat Sequences, Moraxellaceae/*genetics
Phylogeny30798565Computational Prediction of sRNA in Acinetobacter baumannii.Arya S, Dubey V, Sen D, Sharma A, Pathania RMethods Mol Biol10.1007/978-1-4939-9118-1_272019Acinetobacter baumannii/classification/*genetics, Algorithms, *Computational Biology/methods, Databases, Genetic, *Gene Expression Profiling, Gene Expression Regulation, Bacterial, Genome, Bacterial, Genomics/methods, Phylogeny, RNA, Bacterial, RNA, Small Untranslated/*genetics, SoftwareGenetics
31138576Intercellular Transfer of Chromosomal Antimicrobial Resistance Genes between Acinetobacter baumannii Strains Mediated by Prophages.Wachino JI, Jin W, Kimura K, Arakawa YAntimicrob Agents Chemother10.1128/AAC.00334-192019Acinetobacter baumannii/*genetics, Anti-Bacterial Agents/pharmacology, Bacterial Proteins/*genetics, Capsid, Chromosomes, Bacterial, Drug Resistance, Bacterial/*genetics, Gene Transfer, Horizontal, Microbial Sensitivity Tests, Plasmids, Prophages/*genetics, Transduction, Genetic, beta-Lactamases/genetics
Metabolism31281296Quorum and Light Signals Modulate Acetoin/Butanediol Catabolism in Acinetobacter spp.Tuttobene MR, Fernandez-Garcia L, Blasco L, Cribb P, Ambroa A, Muller GL, Fernandez-Cuenca F, Bleriot I, Rodriguez RE, Barbosa BGV, Lopez-Rojas R, Trastoy R, Lopez M, Bou G, Tomas M, Mussi MAFront Microbiol10.3389/fmicb.2019.013762019
Metabolism31383666Therapeutic Efficacy of LN-1-255 in Combination with Imipenem in Severe Infection Caused by Carbapenem-Resistant Acinetobacter baumannii.Vazquez-Ucha JC, Martinez-Guitian M, Maneiro M, Conde-Perez K, Alvarez-Fraga L, Torrens G, Oliver A, Buynak JD, Bonomo RA, Bou G, Gonzalez-Bello C, Poza M, Beceiro AAntimicrob Agents Chemother10.1128/AAC.01092-192019Acinetobacter Infections/*drug therapy/*microbiology, Acinetobacter baumannii/*drug effects/*pathogenicity, Animals, Anti-Infective Agents/*therapeutic use, Bacterial Proteins/genetics/metabolism, Cyclic S-Oxides/*therapeutic use, Drug Resistance, Multiple, Bacterial, Imipenem/*therapeutic use, Male, Mice, Mice, Inbred BALB C, Microbial Sensitivity Tests, Penicillins/*therapeutic use, beta-Lactamase Inhibitors/therapeutic use, beta-Lactamases/genetics/metabolismPathogenicity
Metabolism31555607Involvement of HisF in the Persistence of Acinetobacter baumannii During a Pneumonia Infection.Martinez-Guitian M, Vazquez-Ucha JC, Alvarez-Fraga L, Conde-Perez K, Lasarte-Monterrubio C, Vallejo JA, Bou G, Poza M, Beceiro AFront Cell Infect Microbiol10.3389/fcimb.2019.003102019A549 Cells, Acinetobacter baumannii/enzymology/*genetics/immunology/*metabolism, Aminohydrolases/*genetics/*metabolism, Animals, Disease Models, Animal, Drug Resistance, Multiple, Bacterial, Gene Knockout Techniques, Genes, Bacterial/genetics, Humans, Interleukin-6/metabolism, Lung/immunology, Mice, Mice, Inbred BALB C, Microbial Sensitivity Tests, Pneumonia/*immunology/*microbiology, RAW 264.7 Cells, Transcriptome, Virulence, Virulence FactorsPathogenicity
Pathogenicity31586411Antisense inhibition of lpxB gene expression in Acinetobacter baumannii by peptide-PNA conjugates and synergy with colistin.Martinez-Guitian M, Vazquez-Ucha JC, Alvarez-Fraga L, Conde-Perez K, Bou G, Poza M, Beceiro AJ Antimicrob Chemother10.1093/jac/dkz4092020A549 Cells, Acinetobacter Infections/microbiology, Acinetobacter baumannii/*drug effects/genetics, Animals, Anti-Bacterial Agents/*pharmacology, Bacterial Proteins/*antagonists & inhibitors/genetics, Biosynthetic Pathways, Colistin/*pharmacology, DNA, Antisense/*genetics, Drug Synergism, Gene Expression, Humans, Lipid A/biosynthesis, Male, Mice, Mice, Inbred BALB C, Microbial Sensitivity Tests, Moths/microbiology, Peptide Nucleic Acids/*pharmacology, RNA-Seq
Pathogenicity31600538Imaging of bioluminescent Acinetobacter baumannii in a mouse pneumonia model.Na SH, Oh MH, Jeon H, Lee YK, Lee B, Shin M, Lee JCMicrob Pathog10.1016/j.micpath.2019.1037842019Acinetobacter Infections/*microbiology, Acinetobacter baumannii/chemistry/genetics/*physiology, Animals, Disease Models, Animal, Female, Humans, Luminescent Measurements/*methods, Luminescent Proteins/chemistry/genetics/metabolism, Mice, Mice, Inbred BALB C, Pneumonia/*microbiologyMetabolism
Metabolism31687925A corepressor participates in LexA-independent regulation of error-prone polymerases in Acinetobacter.Peterson MA, Grice AN, Hare JMMicrobiology (Reading)10.1099/mic.0.0008662020Acinetobacter baumannii/enzymology/*genetics/metabolism, Bacterial Proteins/genetics/*metabolism, Binding Sites, Co-Repressor Proteins/genetics/*metabolism, DNA Damage/genetics, DNA-Directed DNA Polymerase/*genetics/metabolism, Gene Expression Regulation, Bacterial, Mutation, Promoter Regions, Genetic, Regulon, SOS Response, Genetics, Serine Endopeptidases/genetics/metabolismEnzymology
Enzymology31706000AdeB efflux pump gene knockdown by mRNA mediated peptide nucleic acid in multidrug resistance Acinetobacter baumannii.Abdi SN, Ghotaslou R, Asgharzadeh M, Mehramouz B, Hasani A, Baghi HB, Tanomand A, Narenji H, Yousefi B, Gholizadeh P, Yousefi M, Bastami M, Ganbarov K, Samadi Kafil HMicrob Pathog10.1016/j.micpath.2019.1038252019Acinetobacter baumannii/drug effects/*genetics/isolation & purification, Anti-Bacterial Agents/pharmacology, Bacterial Proteins/*genetics/metabolism, Ciprofloxacin/pharmacology, Colistin/pharmacology, DNA, Antisense/genetics/pharmacology, DNA, Bacterial/genetics/isolation & purification, Drug Resistance, Multiple, Bacterial/*genetics, Gene Expression Regulation, Bacterial, *Gene Knockdown Techniques, Membrane Transport Proteins/*genetics/metabolism, Microbial Sensitivity Tests, Peptide Nucleic Acids/genetics/pharmacokinetics, RNA, Messenger/genetics/metabolism, Tetracycline/pharmacologyMetabolism
Pathogenicity31837449Diversity of amino acid substitutions in PmrCAB associated with colistin resistance in clinical isolates of Acinetobacter baumannii.Gerson S, Lucassen K, Wille J, Nodari CS, Stefanik D, Nowak J, Wille T, Betts JW, Roca I, Vila J, Cisneros JM, Seifert H, Higgins PGInt J Antimicrob Agents10.1016/j.ijantimicag.2019.1058622019Acinetobacter Infections/drug therapy/*microbiology, Acinetobacter baumannii/drug effects/*genetics, Amino Acid Substitution, Anti-Bacterial Agents/*pharmacology, Bacterial Proteins/*genetics, Colistin/*pharmacology, Drug Resistance, Bacterial/genetics, Greece, Humans, Pneumonia, Ventilator-Associated/drug therapy/*microbiology
Metabolism31864291The sensor kinase BfmS controls production of outer membrane vesicles in Acinetobacter baumannii.Kim SY, Kim MH, Kim SI, Son JH, Kim S, Lee YC, Shin M, Oh MH, Lee JCBMC Microbiol10.1186/s12866-019-1679-02019Acinetobacter baumannii/enzymology/*genetics/*pathogenicity, Bacterial Outer Membrane Proteins/*genetics, Bacterial Proteins/genetics, Gene Expression Regulation, Bacterial, Mutation, Phosphotransferases/*genetics/metabolism, Secretory Vesicles/*metabolismBiotechnology
Metabolism31898255Zur-regulated lipoprotein A contributes to the fitness of Acinetobacter baumannii.Lee EK, Choi CH, Oh MHJ Microbiol10.1007/s12275-020-9531-72020A549 Cells, *Acinetobacter baumannii/pathogenicity/physiology, Animals, Bacterial Proteins/*metabolism, Biofilms, Fimbriae, Bacterial/metabolism, Humans, Lipoprotein(a)/*physiology, Mice, Mice, Inbred BALB C, VirulencePathogenicity
Pathogenicity32007593Effects of different resistance mechanisms on antimicrobial resistance in Acinetobacter baumannii: a strategic system for screening and activity testing of new antibiotics.Tsai YK, Liou CH, Lin JC, Fung CP, Chang FY, Siu LKInt J Antimicrob Agents10.1016/j.ijantimicag.2020.1059182020Acinetobacter Infections/drug therapy/microbiology, Acinetobacter baumannii/*drug effects/*genetics, Aminoglycosides/pharmacology, Anti-Bacterial Agents/*pharmacology, Drug Discovery/*methods, Drug Resistance, Multiple, Bacterial/*genetics, Genetic Engineering, Humans, Membrane Transport Proteins/*genetics, Microbial Sensitivity Tests, Quinolones/pharmacology, Tetracyclines/pharmacology, beta-Lactams/pharmacology
32010115COL(R) Acinetobacter baumannii sRNA Signatures: Computational Comparative Identification and Biological Targets.Cafiso V, Stracquadanio S, Lo Verde F, Dovere V, Zega A, Pigola G, Aranda J, Stefani SFront Microbiol10.3389/fmicb.2019.030752020
Metabolism32023715[Influence of abaR gene knockout on growth metabolism and biofilm formation of Acinetobacter baumannii].Guo HN, Chen Z, Xiang JZhonghua Shao Shang Za Zhi10.3760/cma.j.issn.1009-2587.2020.01.0062020*Acinetobacter baumannii, Anti-Bacterial Agents, *Biofilms, Gene Knockout Techniques, Polymerase Chain Reaction
Metabolism32049284Role of ppGpp-regulated efflux genes in Acinetobacter baumannii.Jung HW, Kim K, Islam MM, Lee JC, Shin MJ Antimicrob Chemother10.1093/jac/dkaa0142020*Acinetobacter baumannii/genetics/metabolism, Anti-Bacterial Agents/pharmacology, Bacterial Proteins/genetics/metabolism, Drug Resistance, Multiple, Bacterial/genetics, Guanosine Tetraphosphate, Membrane Transport Proteins/genetics, Microbial Sensitivity Tests
Genetics32081464Complete genome sequence and genome-scale metabolic modelling of Acinetobacter baumannii type strain ATCC 19606.Zhu Y, Lu J, Zhao J, Zhang X, Yu HH, Velkov T, Li JInt J Med Microbiol10.1016/j.ijmm.2020.1514122020Acinetobacter baumannii/drug effects/*genetics/*metabolism, Anti-Bacterial Agents/pharmacology, Bacterial Proteins/genetics/*metabolism, DNA Transposable Elements, Drug Resistance, Multiple, Bacterial/genetics, Genes, Bacterial, *Genome, Bacterial, Microbial Sensitivity Tests, Virulence Factors/genetics, Whole Genome SequencingMetabolism
Metabolism32255384Direct interaction between RecA and a CheW-like protein is required for surface-associated motility, chemotaxis and the full virulence of Acinetobacter baumannii strain ATCC 17978.Corral J, Perez-Varela M, Barbe J, Aranda JVirulence10.1080/21505594.2020.17489232020Acinetobacter Infections/microbiology, Acinetobacter baumannii/genetics/metabolism/*pathogenicity, Animals, Bacterial Proteins/genetics/*metabolism, Caenorhabditis elegans/microbiology, *Chemotaxis, DNA-Binding Proteins/genetics/*metabolism, Moths/microbiology, Rec A Recombinases/genetics/*metabolism, Virulence/genetics
Metabolism32324528A response regulator protein with antar domain, AvnR, in Acinetobacter baumannii ATCC 17978 impacts its virulence and amino acid metabolism.De Silva PM, Patidar R, Graham CI, Brassinga AKC, Kumar AMicrobiology (Reading)10.1099/mic.0.0009132020A549 Cells, Acinetobacter Infections/*microbiology, Acinetobacter baumannii/genetics/*pathogenicity/physiology, Amino Acids/*metabolism, Bacterial Proteins/*chemistry/genetics/*metabolism, Biofilms, *Gene Expression Regulation, Bacterial, Humans, Protein Domains, Transcription Factors/genetics/metabolism, VirulencePathogenicity
Pathogenicity32324853Role of PstS in the Pathogenesis of Acinetobacter baumannii Under Microaerobiosis and Normoxia.Gil-Marques ML, Labrador Herrera G, Miro Canturri A, Pachon J, Smani Y, Pachon-Ibanez MEJ Infect Dis10.1093/infdis/jiaa2012020A549 Cells, Acinetobacter Infections/microbiology, Acinetobacter baumannii/*genetics/growth & development/*pathogenicity, Aerobiosis, Animals, Bacterial Adhesion/genetics, Bacterial Proteins/*genetics, Biofilms, Cell Death, Epithelial Cells/metabolism/microbiology, Female, Gene Expression Regulation, Bacterial, Humans, Mice, Mice, Inbred C57BL, Oxygen/pharmacology, Peritonitis/microbiology, Phosphate-Binding Proteins/*genetics, Virulence/genetics, Virulence Factors/geneticsMetabolism
32357487Mutation of the Carboxy-Terminal Processing Protease in Acinetobacter baumannii Affects Motility, Leads to Loss of Membrane Integrity, and Reduces Virulence.Roy R, You RI, Lin MD, Lin NTPathogens10.3390/pathogens90503222020
32368105Discovery of a Novel Hypervirulent Acinetobacter baumannii Strain in a Case of Community-Acquired Pneumonia.Zhou H, Larkin PMK, Huang J, Yao Y, Zhu B, Yang Q, Hua X, Zhou J, Yang S, Yu YInfect Drug Resist10.2147/IDR.S2440442020
Biotechnology32523805Characterization of biofilm production in different strains of Acinetobacter baumannii and the effects of chemical compounds on biofilm formation.Lin MF, Lin YY, Lan CYPeerJ10.7717/peerj.90202020
32582088Phenotypic Variation and Carbapenem Resistance Potential in OXA-499-Producing Acinetobacter pittii.Zhang L, Fu Y, Han X, Xu Q, Weng S, Yan B, Liu L, Hua X, Chen Y, Yu YFront Microbiol10.3389/fmicb.2020.011342020
Metabolism32832672Peptidoglycan editing provides immunity to Acinetobacter baumannii during bacterial warfare.Le NH, Peters K, Espaillat A, Sheldon JR, Gray J, Di Venanzio G, Lopez J, Djahanschiri B, Mueller EA, Hennon SW, Levin PA, Ebersberger I, Skaar EP, Cava F, Vollmer W, Feldman MFSci Adv10.1126/sciadv.abb56142020*Acinetobacter baumannii/genetics, Amino Acids/metabolism, Bacterial Proteins/genetics/metabolism, *Biological Warfare, Humans, Hydrogen Peroxide/metabolism, Peptidoglycan/metabolism, PhylogenyPathogenicity
Pathogenicity32840575Global Transcriptomic Analysis During Murine Pneumonia Infection Reveals New Virulence Factors in Acinetobacter baumannii.Martinez-Guitian M, Vazquez-Ucha JC, Alvarez-Fraga L, Conde-Perez K, Vallejo JA, Perina A, Bou G, Poza M, Beceiro AJ Infect Dis10.1093/infdis/jiaa5222021*Acinetobacter Infections/microbiology, *Acinetobacter baumannii/genetics, Animals, Bacterial Adhesion, Cells, Cultured, Epithelial Cells/microbiology, Humans, Mice, *Pneumonia, Bacterial/microbiology, *Transcriptome, *Virulence Factors/geneticsTranscriptome
Pathogenicity33372826Genomic and phenotypic analyses of multidrug-resistant Acinetobacter baumannii NCCP 16007 isolated from a patient with a urinary tract infection.Kim M, Park J, Park WVirulence10.1080/21505594.2020.18674212021Acinetobacter Infections/microbiology/*urine, Acinetobacter baumannii/classification/*drug effects/*genetics/pathogenicity, Animals, Anti-Bacterial Agents/*pharmacology, Bacterial Proteins/genetics, Biofilms, Drug Resistance, Multiple, Bacterial/*genetics, Gene Transfer, Horizontal, *Genome, Bacterial, Genomics, Humans, Larva/microbiology, Microbial Sensitivity Tests, Moths/microbiology, *Phenotype, Urinary Tract Infections/*microbiologyGenetics
Metabolism33461493The role of Zur-regulated lipoprotein A in bacterial morphology, antimicrobial susceptibility, and production of outer membrane vesicles in Acinetobacter baumannii.Kim N, Kim HJ, Oh MH, Kim SY, Kim MH, Son JH, Kim SI, Shin M, Lee YC, Lee JCBMC Microbiol10.1186/s12866-020-02083-02021A549 Cells, Acinetobacter baumannii/drug effects/genetics/metabolism/*pathogenicity, Anti-Bacterial Agents/pharmacology, Bacterial Proteins/genetics/metabolism, Computational Biology/*methods, Computer Simulation, *Drug Resistance, Bacterial, Extracellular Vesicles/metabolism, Gentamicins/pharmacology, Humans, Lipoprotein(a)/*genetics/metabolism, Mutation, Zinc/metabolismPathogenicity
Pathogenicity33501980Transferable Acinetobacter baumannii plasmid pDETAB2 encodes OXA-58 and NDM-1 and represents a new class of antibiotic resistance plasmids.Liu H, Moran RA, Chen Y, Doughty EL, Hua X, Jiang Y, Xu Q, Zhang L, Blair JMA, McNally A, van Schaik W, Yu YJ Antimicrob Chemother10.1093/jac/dkab0052021*Acinetobacter baumannii/genetics, Anti-Bacterial Agents/pharmacology, Humans, Microbial Sensitivity Tests, Multilocus Sequence Typing, Plasmids/genetics, beta-Lactamases/genetics
Pathogenicity33610507d-mannose-sensitive pilus of Acinetobacter baumannii is linked to biofilm formation and adherence onto respiratory tract epithelial cells.Chen CL, Dudek A, Liang YH, Janapatla RP, Lee HY, Hsu L, Kuo HY, Chiu CHJ Microbiol Immunol Infect10.1016/j.jmii.2021.01.0082021*Acinetobacter baumannii, Biofilms, Epithelial Cells, Escherichia coli/genetics, Humans, Mannose, Respiratory System
33643267AOA-2 Derivatives as Outer Membrane Protein A Inhibitors for Treatment of Gram-Negative Bacilli Infections.Ayerbe-Algaba R, Bayo N, Verdu E, Parra-Millan R, Seco J, Teixido M, Pachon J, Giralt E, Smani YFront Microbiol10.3389/fmicb.2021.6343232021
Metabolism33749577Dissemination of novel Tn7 family transposons carrying genes for synthesis and uptake of fimsbactin siderophores among Acinetobacter baumannii isolates.Hamidian M, Hall RMMicrob Genom10.1099/mgen.0.0005482021Acinetobacter baumannii/*genetics/*metabolism, Bacterial Proteins/*genetics/metabolism, *DNA Transposable Elements, Gene Transfer, Horizontal, Genome, Bacterial, Phylogeny, Recombination, Genetic, Siderophores/*metabolismGenetics
Metabolism33782056Essential Gene Analysis in Acinetobacter baumannii by High-Density Transposon Mutagenesis and CRISPR Interference.Bai J, Dai Y, Farinha A, Tang AY, Syal S, Vargas-Cuebas G, van Opijnen T, Isberg RR, Geisinger EJ Bacteriol10.1128/JB.00565-202021Acinetobacter baumannii/*genetics, Bacterial Capsules, Bacterial Proteins/genetics/metabolism, *Clustered Regularly Interspaced Short Palindromic Repeats, DNA Transposable Elements/genetics/*physiology, Gene Expression Regulation, Bacterial, Gene Knockdown Techniques, Mutagenesis
33803549Regulation of tert-Butyl Hydroperoxide Resistance by Chromosomal OhrR in A. baumannii ATCC 19606.Chen SJ, Shu HY, Lin GHMicroorganisms10.3390/microorganisms90306292021
Genetics33912474Two Acinetobacter baumannii Isolates Obtained From a Fatal Necrotizing Fasciitis Infection Display Distinct Genomic and Phenotypic Characteristics in Comparison to Type Strains.Grier JT, Arivett BA, Ramirez MS, Chosed RJ, Bigner JA, Ohneck EJ, Metz ML, Wood CR, Arce S, Tartaro A, Relich RF, Actis LA, Fiester SEFront Cell Infect Microbiol10.3389/fcimb.2021.6356732021*Acinetobacter Infections, *Acinetobacter baumannii, Anti-Bacterial Agents, Biofilms, *Fasciitis, Necrotizing, Genomics, Humans, PhenotypePathogenicity
Metabolism34097477Comparison of the Acinetobacter baumannii Reference Strains ATCC 17978 and ATCC 19606 in Antimicrobial Resistance Mediated by the AdeABC Efflux Pump.Lucassen K, Gerson S, Xanthopoulou K, Wille J, Wille T, Seifert H, Higgins PGAntimicrob Agents Chemother10.1128/AAC.00570-212021*Acinetobacter baumannii/genetics/metabolism, Anti-Bacterial Agents/pharmacology, Bacterial Proteins/genetics/metabolism, Drug Resistance, Bacterial/genetics, Drug Resistance, Multiple, Bacterial/genetics, Membrane Transport Proteins/genetics, Microbial Sensitivity Tests
Biotechnology34203028Carboxy-Terminal Processing Protease Controls Production of Outer Membrane Vesicles and Biofilm in Acinetobacter baumannii.Roy R, You RI, Chang CH, Yang CY, Lin NTMicroorganisms10.3390/microorganisms90613362021
34311571BonA from Acinetobacter baumannii Forms a Divisome-Localized Decamer That Supports Outer Envelope Function.Grinter R, Morris FC, Dunstan RA, Leung PM, Kropp A, Belousoff M, Gunasinghe SD, Scott NE, Beckham S, Peleg AY, Greening C, Li J, Heinz E, Lithgow TmBio10.1128/mBio.01480-212021
Proteome34364435An integrated strategy for the construction of a species-specific glycan library for mass spectrometry-based intact glycopeptide analyses.Meng X, Li L, Wang XTalanta10.1016/j.talanta.2021.1226262021Animals, *Glycopeptides/metabolism, Glycosylation, Polysaccharides, Software, *Tandem Mass SpectrometryMetabolism
Stress34421881The gigA/gigB Genes Regulate the Growth, Stress Response, and Virulence of Acinetobacter baumannii ATCC 17978 Strain.Zhou H, Gebhardt MJ, Czyz DM, Yao Y, Shuman HAFront Microbiol10.3389/fmicb.2021.7239492021
Pathogenicity34449059Screening of small molecules attenuating biofilm formation of Acinetobacter baumannii by inhibition of ompA promoter activity.Na SH, Jeon H, Oh MH, Kim YJ, Lee JCJ Microbiol10.1007/s12275-021-1394-z2021Acinetobacter Infections/*microbiology, Acinetobacter baumannii/*drug effects/genetics/pathogenicity/physiology, Anti-Bacterial Agents/*pharmacology, Bacterial Outer Membrane Proteins/genetics/*metabolism, Biofilms/*drug effects, Drug Evaluation, Preclinical, Gene Expression Regulation, Bacterial/drug effects, Humans, Promoter Regions, Genetic/*drug effects, Small Molecule Libraries/*pharmacology, Virulence/drug effectsMetabolism
Genetics34460288Identification of Two Variants of Acinetobacter baumannii Strain ATCC 17978 with Distinct Genotypes and Phenotypes.Wijers CDM, Pham L, Menon S, Boyd KL, Noel HR, Skaar EP, Gaddy JA, Palmer LD, Noto MJInfect Immun10.1128/IAI.00454-212021Acinetobacter Infections/*microbiology, Acinetobacter baumannii/*classification/*genetics, Animals, Bacterial Proteins/genetics, Biomarkers, Disease Models, Animal, Disease Susceptibility, *Genetic Variation, *Genotype, Host-Pathogen Interactions, Mice, *PhenotypePhenotype
34522977Mechanism Underlying the Role of LuxR Family Transcriptional Regulator abaR in Biofilm Formation by Acinetobacter baumannii.Sun X, Xiang JCurr Microbiol10.1007/s00284-021-02654-y2021*Acinetobacter baumannii/genetics, Biofilms, Repressor Proteins/genetics/*physiology, Trans-Activators/genetics/*physiology
34572317Assessment of Antibiofilm Potencies of Nervonic and Oleic Acid against Acinetobacter baumannii Using In Vitro and Computational Approaches.Khadke SK, Lee JH, Kim YG, Raj V, Lee JBiomedicines10.3390/biomedicines90911332021
Metabolism34588306Killing of Gram-negative and Gram-positive bacteria by a bifunctional cell wall-targeting T6SS effector.Le NH, Pinedo V, Lopez J, Cava F, Feldman MFProc Natl Acad Sci U S A10.1073/pnas.21065551182021Bacterial Proteins/*metabolism, Biological Transport/physiology, Cell Wall/*metabolism, Gram-Negative Bacteria/*metabolism, Gram-Positive Bacteria/*metabolism, Type VI Secretion Systems/*metabolism
34653022Medical Evaluation of the Antimicrobial Activity of Rose Oil on Some Standard Bacteria Strains and Clinical Isolates.Demirel SAltern Ther Health MedAT68872021
34659171Phosphorylation of Extracellular Proteins in Acinetobacter baumannii in Sessile Mode of Growth.Massier S, Robin B, Megroz M, Wright A, Harper M, Hayes B, Cosette P, Broutin I, Boyce JD, De E, Hardouin JFront Microbiol10.3389/fmicb.2021.7387802021
34675911In-Depth Analysis of the Role of the Acinetobactin Cluster in the Virulence of Acinetobacter baumannii.Conde-Perez K, Vazquez-Ucha JC, Alvarez-Fraga L, Ageitos L, Rumbo-Feal S, Martinez-Guitian M, Trigo-Tasende N, Rodriguez J, Bou G, Jimenez C, Beceiro A, Poza MFront Microbiol10.3389/fmicb.2021.7520702021
Metabolism34696704Global regulator DksA modulates virulence of Acinetobacter baumannii.Kim N, Son JH, Kim K, Kim HJ, Kim YJ, Shin M, Lee JCVirulence10.1080/21505594.2021.19952532021*Acinetobacter baumannii, Animals, Bacterial Proteins/genetics/metabolism, Biofilms, Gene Expression Regulation, Bacterial, Mice, Virulence
Pathogenicity34717227Benzalkonium chloride antagonises aminoglycoside antibiotics and promotes evolution of resistance.Short FL, Lee V, Mamun R, Malmberg R, Li L, Espinosa MI, Venkatesan K, Paulsen ITEBioMedicine10.1016/j.ebiom.2021.1036532021Acinetobacter baumannii/*drug effects/physiology, Aminoglycosides/*pharmacology, Anti-Bacterial Agents/pharmacology, Benzalkonium Compounds/*adverse effects/pharmacology, Disinfectants/adverse effects/pharmacology, Drug Resistance, Bacterial/*drug effects, Microbial Sensitivity Tests
Pathogenicity34830146Therapeutic Effects of Inhibitor of ompA Expression against Carbapenem-Resistant Acinetobacter baumannii Strains.Na SH, Jeon H, Oh MH, Kim YJ, Chu M, Lee IY, Lee JCInt J Mol Sci10.3390/ijms2222122572021Acinetobacter Infections/microbiology/*prevention & control, Acinetobacter baumannii/*drug effects/genetics/physiology, Animals, Anti-Bacterial Agents/administration & dosage/*pharmacology, Bacterial Outer Membrane Proteins/*genetics/metabolism, Biofilms/drug effects/growth & development, Carbapenems/*pharmacology, Drug Resistance, Multiple, Bacterial/*drug effects/genetics, Female, Gene Expression Regulation, Bacterial/*drug effects, Humans, Mice, Inbred BALB C, Microbial Sensitivity Tests/methods, Promoter Regions, Genetic/genetics, Small Molecule Libraries/administration & dosage/pharmacology, Survival AnalysisGenetics
Enzymology34851156Sporadic Dissemination of tet(X3) and tet(X6) Mediated by Highly Diverse Plasmidomes among Livestock-Associated Acinetobacter.Cheng YY, Liu Y, Chen Y, Huang FM, Chen RC, Xiao YH, Zhou KMicrobiol Spectr10.1128/Spectrum.01141-212021Acinetobacter/drug effects/*genetics/*isolation & purification, Acinetobacter Infections/drug therapy/*veterinary, Animals, Anti-Bacterial Agents/*pharmacology, Bacterial Proteins/genetics, Cattle, Livestock/microbiology, Microbial Sensitivity Tests, Mixed Function Oxygenases/genetics, Plasmids/genetics, Sheep/microbiology, Swine/microbiology, Tetracycline Resistance/*genetics, Tigecycline/*pharmacologyPhylogeny
34925284Subinhibitory Concentrations of Clinically-Relevant Antimicrobials Affect Resistance-Nodulation-Division Family Promoter Activity in Acinetobacter baumannii.Prieto Martin Gil S, Tajuelo A, Lopez-Siles M, McConnell MJFront Microbiol10.3389/fmicb.2021.7802012021
34943684DksA Modulates Antimicrobial Susceptibility of Acinetobacter baumannii.Kim N, Son JH, Kim K, Kim HJ, Shin M, Lee JCAntibiotics (Basel)10.3390/antibiotics101214722021
35018330Atorvastatin does not display an antimicrobial activity on its own nor potentiates the activity of other antibiotics against Acinetobacter baumannii ATCC17978 or A. baumannii AB030.Kornelsen V, Unger M, Kumar AAccess Microbiol10.1099/acmi.0.0002882021
Stress35129693Tobramycin Stress Induced Differential Gene Expression in Acinetobacter baumannii.Kashyap S, Sharma P, Capalash NCurr Microbiol10.1007/s00284-022-02788-72022*Acinetobacter baumannii/genetics, Amikacin, Anti-Bacterial Agents/pharmacology/therapeutic use, Drug Resistance, Multiple, Bacterial, Gene Expression, Microbial Sensitivity Tests, Tobramycin/pharmacology
Pathogenicity35151875Fighting Acinetobacter baumannii infections with the acylase PvdQ.Vogel J, Jansen L, Setroikromo R, Cavallo FM, van Dijl JM, Quax WJMicrobes Infect10.1016/j.micinf.2022.1049512022*Acinetobacter Infections/drug therapy/microbiology, *Acinetobacter baumannii, Acyl-Butyrolactones, Amidohydrolases, Anti-Bacterial Agents/pharmacology/therapeutic use, Biofilms, Humans, Quorum Sensing
Metabolism35234505iTRAQ-Based Quantitative Proteomic Analysis of Acinetobacter baumannii under Hypoxia and Normoxia Reveals the Role of OmpW as a Virulence Factor.Gil-Marques ML, Pachon J, Smani YMicrobiol Spectr10.1128/spectrum.02328-212022*Acinetobacter baumannii/genetics/metabolism, Animals, Biofilms, Hypoxia, Mice, Proteome/metabolism, Proteomics, Virulence Factors/genetics/metabolismProteome
Metabolism35281445Effect of Hcp Iron Ion Regulation on the Interaction Between Acinetobacter baumannii With Human Pulmonary Alveolar Epithelial Cells and Biofilm Formation.Pan P, Wang X, Chen Y, Chen Q, Yang Y, Wei C, Cheng T, Wan H, Yu DFront Cell Infect Microbiol10.3389/fcimb.2022.7616042022*Acinetobacter baumannii/pathogenicity, *Alveolar Epithelial Cells/microbiology, Bacterial Adhesion, *Bacterial Proteins/metabolism, Biofilms, *Hemolysin Proteins/metabolism, Humans, Ions/metabolism, Iron/metabolismPathogenicity
Metabolism35402311The Influence of Blue Light and the BlsA Photoreceptor on the Oxidative Stress Resistance Mechanisms of Acinetobacter baumannii.Squire MS, Townsend HA, Actis LAFront Cell Infect Microbiol10.3389/fcimb.2022.8569532022*Acinetobacter baumannii/genetics, Bacterial Proteins/metabolism, Biofilms, Catalase/metabolism, Humans, Iron/metabolism, Oxidative StressPathogenicity
35503000Ketoprofen, piroxicam and indomethacin-suppressed quorum sensing and virulence factors in Acinetobacter baumannii.Elshaer SL, Shaldam MA, Shaaban MIJ Appl Microbiol10.1111/jam.156092022
Pathogenicity35586934Bactericidal Effect of Cecropin A Fused Endolysin on Drug-Resistant Gram-Negative Pathogens.Lim J, Hong J, Jung Y, Ha J, Kim H, Myung H, Song MJ Microbiol Biotechnol10.4014/jmb.2205.050092022
355957666-Bromo-2-naphthol from Silene armeria extract sensitizes Acinetobacter baumannii strains to polymyxin.Kang M, Kim W, Lee J, Jung HS, Jeon CO, Park WSci Rep10.1038/s41598-022-11995-y2022*Acinetobacter Infections/drug therapy/microbiology, *Acinetobacter baumannii, Anti-Bacterial Agents/pharmacology, Drug Resistance, Multiple, Bacterial, Drug Synergism, Microbial Sensitivity Tests, Naphthols, Plant Extracts/pharmacology, Polymyxin B/pharmacology, Polymyxins/pharmacology, *Silene
Pathogenicity35614377Eradication of drug-resistant Acinetobacter baumannii by cell-penetrating peptide fused endolysin.Lim J, Jang J, Myung H, Song MJ Microbiol10.1007/s12275-022-2107-y2022
35618210In-vitro activity of sulbactam-durlobactam against carbapenem-resistant Acinetobacter baumannii and mechanisms of resistance.Findlay J, Poirel L, Bouvier M, Nordmann PJ Glob Antimicrob Resist10.1016/j.jgar.2022.05.0112022
35787944Recombinant AcnB, NrdR and RibD of Acinetobacter baumannii and their potential interaction with DNA adenine methyltransferase AamA.Weber K, Doellinger J, Jeffries CM, Wilharm GProtein Expr Purif10.1016/j.pep.2022.1061342022*Acinetobacter baumannii/genetics, Adenine, DNA, Methyltransferases, Scattering, Small Angle, X-Ray Diffraction
35858582Histamine Produced by Gram-Negative Bacteria Impairs Neutrophil's Antimicrobial Response by Engaging the Histamine 2 Receptor.Dib K, El Banna A, Radulescu C, Lopez Campos G, Sheehan G, Kavanagh KJ Innate Immun10.1159/0005255362022
35867473Polyphosphate Kinase Is Required for the Processes of Virulence and Persistence in Acinetobacter baumannii.Lv H, Zhou Y, Liu B, Guan J, Zhang P, Deng X, Li D, Wang JMicrobiol Spectr10.1128/spectrum.01230-222022*Acinetobacter baumannii/genetics, Adenosine Monophosphate, Animals, Biofilms, Fatty Acids, Glycerophospholipids, Hydrogen Peroxide, Mice, Phosphotransferases (Phosphate Group Acceptor), Virulence/genetics
Metabolism358678723-indoleacetonitrile attenuates biofilm formation and enhances sensitivity to imipenem in Acinetobacter baumannii.Kashyap S, Sidhu H, Sharma P, Capalash NPathog Dis10.1093/femspd/ftac0292022Acetonitriles/*pharmacology, *Acinetobacter Infections/drug therapy, *Acinetobacter baumannii/genetics, Anti-Bacterial Agents/therapeutic use, Bacterial Proteins/genetics/metabolism, Biofilms, Carbapenems/metabolism/pharmacology/therapeutic use, Humans, Imipenem/pharmacology, Microbial Sensitivity Tests, beta-Lactamases/genetics/metabolismPathogenicity
35899254Co-evolutionary adaptations of Acinetobacter baumannii and a clinical carbapenemase-encoding plasmid during carbapenem exposure.Zhang L, Fu Y, Zhang L, Xu Q, Yang Y, He J, Leptihn S, Loh B, Moran RA, van Schaik W, Toleman MA, Chen Q, Liu L, Yu Y, Hua XEvol Appl10.1111/eva.134412022
Metabolism36361923Complementary Regulation of BfmRS Two-Component and AbaIR Quorum Sensing Systems to Express Virulence-Associated Genes in Acinetobacter baumannii.Kim HJ, Kim NY, Ko SY, Park SY, Oh MH, Shin MS, Lee YC, Lee JCInt J Mol Sci10.3390/ijms2321131362022*Acinetobacter baumannii, Virulence/genetics, Quorum Sensing/genetics, Bacterial Proteins/genetics/metabolism, Biofilms, Gene Expression Regulation, Bacterial

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@idauthorstitledoi/urlcatalogue
20215Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ10.1099/ijsem.0.004332
24477Curators of the DSMZhttps://www.dsmz.de/collection/catalogue/details/culture/DSM-105126Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSM 105126)
34573Curators of the CIPhttps://brclims.pasteur.fr/brcWeb/souche/detail/1/16123
66792Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg OvermannAutomatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information)https://diaspora-project.de/progress.html#genomes
68369Automatically annotated from API 20NE
68371Automatically annotated from API 50CH acid
68382Automatically annotated from API zym
69480Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg OvermannPredictions based on genome sequence made in the Diaspora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information)https://diaspora-project.de/progress.html#genomes
69481Xiao-Yin To, René Mreches, Martin Binder, Alice C. McHardy, Philipp C. MünchPredictions based on the model GenomeNet Sporulation v. 110.21203/rs.3.rs-2527258/v1
90995Reimer, L.C., Lissin, A.,Schober, I., Witte,J.F., Podstawka, A., Lüken, H., Bunk, B.,Overmann, J.StrainInfo: A central database for resolving microbial strain identifiers10.60712/SI-ID13527.1
116743Curators of the CIPhttps://catalogue-crbip.pasteur.fr/fiche_catalogue.xhtml?crbip=CIP%2053.77Collection of Institut Pasteur (CIP 53.77)