    @article{lin343977,
    title   = {Numerical Modeling of Gentamicin Transport in Agricultural Soils: Implications for Environmental Pollution},    
    author  = {Morales-Duran N, Fuentes S, Garcia-Gallego J, Trevino-Resendez J, Garcia-Espinoza J, Morones-Ramirez R, Chavez C.},    
    journal = {Antibiotics (Basel)},    
    year    = {2025},    
        
            
    }
    @article{lin344056,
    title   = {Micromonospora RNA polymerase activity changes during stationary phase.},    
    author  = {Lin LS, Rothstein DM.},    
    journal = {J Gen Microbiol},    
    year    = {1992},    
    doi     = {10.1099/00221287-138-9-1881},    
    pmid    = {1402789}        
    }
    @article{lin344084,
    title   = {Mutations in the P1 promoter region of Micromonospora echinospora.},    
    author  = {Lin LS, Rothstein DM.},    
    journal = {J Bacteriol},    
    year    = {1992},    
    doi     = {10.1128/jb.174.10.3111-3117.1992},    
    pmid    = {1577683}        
    }
    @article{lin344069,
    title   = {Conditions for protoplasting, regenerating, and transforming the calicheamicin producer, Micromonospora echinospora.},    
    author  = {Love SF, Maiese WM, Rothstein DM.},    
    journal = {Appl Environ Microbiol},    
    year    = {1992},    
    doi     = {10.1128/aem.58.4.1376-1378.1992},    
    pmid    = {1599256}        
    }
    @article{lin344080,
    title   = {Isolation of mutants blocked in calicheamicin biosynthesis.},    
    author  = {Rothstein DM, Love SF.},    
    journal = {J Bacteriol},    
    year    = {1991},    
    doi     = {10.1128/jb.173.23.7716-7718.1991},    
    pmid    = {1938969}        
    }
    @article{lin344092,
    title   = {Temporally regulated tandem promoters in Micromonospora echinospora.},    
    author  = {Baum EZ, Love SF, Rothstein DM.},    
    journal = {J Bacteriol},    
    year    = {1988},    
    doi     = {10.1128/jb.170.1.71-77.1988},    
    pmid    = {2447066}        
    }
    @article{lin344089,
    title   = {Transcription from the P1 promoters of Micromonospora echinospora in the absence of native upstream DNA sequences.},    
    author  = {Baum EZ, Buttner MJ, Lin LS, Rothstein DM.},    
    journal = {J Bacteriol},    
    year    = {1989},    
    doi     = {10.1128/jb.171.12.6503-6510.1989},    
    pmid    = {2592343}        
    }
    @article{lin344073,
    title   = {Calicheamicins, a novel family of antitumor antibiotics: taxonomy, fermentation and biological properties.},    
    author  = {Maiese WM, Lechevalier MP, Lechevalier HA, Korshalla J, Kuck N, Fantini A, Wildey MJ, Thomas J, Greenstein M.},    
    journal = {J Antibiot (Tokyo)},    
    year    = {1989},    
    doi     = {10.7164/antibiotics.42.558},    
    pmid    = {2722671}        
    }
    @article{lin344102,
    title   = {Metabolism of endogenous trehalose by Streptomyces griseus spores and by spores or cells of other actinomycetes.},    
    author  = {McBride MJ, Ensign JC.},    
    journal = {J Bacteriol},    
    year    = {1987},    
    doi     = {10.1128/jb.169.11.5002-5007.1987},    
    pmid    = {3117770}        
    }
    @article{lin344059,
    title   = {Clostomicins, new antibiotics produced by Micromonospora echinospora subsp. armeniaca subsp. nov. I. Production, isolation, and physico-chemical and biological properties.},    
    author  = {Omura S, Imamura N, Oiwa R, Kuga H, Iwata R, Masuma R, Iwai Y.},    
    journal = {J Antibiot (Tokyo)},    
    year    = {1986},    
    doi     = {10.7164/antibiotics.39.1407},    
    pmid    = {3781911}        
    }
    @article{lin344057,
    title   = {Clostomicins, new antibiotics produced by Micromonospora echinospora subsp. armeniaca subsp. nov. II. Taxonomic study of the producing microorganism.},    
    author  = {Takahashi Y, Iwai Y, Omura S.},    
    journal = {J Antibiot (Tokyo)},    
    year    = {1986},    
    doi     = {10.7164/antibiotics.39.1413},    
    pmid    = {3781912}        
    }
    @article{lin185526,
    title   = {Genetic recombination in Micromonospora.},    
    author  = {Beretta M, Betti M, Polsinelli M.},    
    journal = {J Bacteriol},    
    year    = {1971},    
    doi     = {10.1128/jb.107.2.415-419.1971},    
    pmid    = {5113596}        
    }
    @article{lin344077,
    title   = {Microbial products. IV. X-14847, a new aminoglycoside from Micromonospora echinospora.},    
    author  = {Maehr H, Liu CM, Hermann T, Prosser BL, Smallheer JM, Palleroni NJ.},    
    journal = {J Antibiot (Tokyo)},    
    year    = {1980},    
    doi     = {10.7164/antibiotics.33.1431},    
    pmid    = {7251485}        
    }
    @article{lin344034,
    title   = {YM-47515, a novel isonitrile antibiotic from Micromonospora echinospora subsp. echinospora.},    
    author  = {Sugawara T, Tanaka A, Imai H, Nagai K, Suzuki K.},    
    journal = {J Antibiot (Tokyo)},    
    year    = {1997},    
    doi     = {10.7164/antibiotics.50.944},    
    pmid    = {9592568}        
    }
    @article{lin344105,
    title   = {Genes for production of the enediyne antitumor antibiotic C-1027 in Streptomyces globisporus are clustered with the cagA gene that encodes the C-1027 apoprotein.},    
    author  = {Liu W, Shen B.},    
    journal = {Antimicrob Agents Chemother},    
    year    = {2000},    
    doi     = {10.1128/aac.44.2.382-392.2000},    
    pmid    = {10639366}        
    }
    @article{lin19563,
    title   = {Response of Micromonospora echinospora (NCIMB 12744) spores to heat treatment with evidence of a heat activation phenomenon.},    
    author  = {Hoskisson PA, Hobbs G, Sharples GP},    
    journal = {Lett Appl Microbiol},    
    year    = {2000},    
    doi     = {10.1046/j.1472-765x.2000.00680.x},    
    pmid    = {10736011}        
    }
    @article{lin344044,
    title   = {Intrageneric relationships among Micromonospora species deduced from gyrB-based phylogeny and DNA relatedness.},    
    author  = {Kasai H, Tamura T, Harayama S.},    
    journal = {Int J Syst Evol Microbiol},    
    year    = {2000},    
    doi     = {10.1099/00207713-50-1-127},    
    pmid    = {10826795}        
    }
    @article{lin19562,
    title   = {Antibiotic production, accumulation of intracellular carbon reserves, and sporulation in Micromonospora echinospora (ATCC 15837).},    
    author  = {Hoskisson PA, Hobbs G, Sharples GP},    
    journal = {Can J Microbiol},    
    year    = {2001},    
        
    pmid    = {11261494}        
    }
    @article{lin19561,
    title   = {The importance of amino acids as carbon sources for Micromonospora echinospora (ATCC 15837).},    
    author  = {Hoskisson PA, Sharples GP, Hobbs G},    
    journal = {Lett Appl Microbiol},    
    year    = {2003},    
    doi     = {10.1046/j.1472-765x.2003.01306.x},    
    pmid    = {12680936}        
    }
    @article{lin344104,
    title   = {Functional angucycline-like antibiotic gene cluster in the terminal inverted repeats of the Streptomyces ambofaciens linear chromosome.},    
    author  = {Pang X, Aigle B, Girardet JM, Mangenot S, Pernodet JL, Decaris B, Leblond P.},    
    journal = {Antimicrob Agents Chemother},    
    year    = {2004},    
    doi     = {10.1128/aac.48.2.575-588.2004},    
    pmid    = {14742212}        
    }
    @article{lin344032,
    title   = {Phylogenetic analysis of the genera Streptomyces and Kitasatospora based on partial RNA polymerase beta-subunit gene (rpoB) sequences.},    
    author  = {Kim BJ, Kim CJ, Chun J, Koh YH, Lee SH, Hyun JW, Cha CY, Kook YH.},    
    journal = {Int J Syst Evol Microbiol},    
    year    = {2004},    
    doi     = {10.1099/ijs.0.02941-0},    
    pmid    = {15023980}        
    }
    @article{lin344100,
    title   = {Two oligopeptide-permease-encoding genes in the clavulanic acid cluster of Streptomyces clavuligerus are essential for production of the beta-lactamase inhibitor.},    
    author  = {Lorenzana LM, Perez-Redondo R, Santamarta I, Martin JF, Liras P.},    
    journal = {J Bacteriol},    
    year    = {2004},    
    doi     = {10.1128/jb.186.11.3431-3438.2004},    
    pmid    = {15150229}        
    }
    @article{lin344028,
    title   = {A gene cluster for biosynthesis of kanamycin from Streptomyces kanamyceticus: comparison with gentamicin biosynthetic gene cluster.},    
    author  = {Kharel MK, Subba B, Basnet DB, Woo JS, Lee HC, Liou K, Sohng JK.},    
    journal = {Arch Biochem Biophys},    
    year    = {2004},    
    doi     = {10.1016/j.abb.2004.06.009},    
    pmid    = {15313224}        
    }
    @article{lin344027,
    title   = {Tumour-targeted chemotherapy with immunoconjugates of calicheamicin.},    
    author  = {Damle NK.},    
    journal = {Expert Opin Biol Ther},    
    year    = {2004},    
    doi     = {10.1517/14712598.4.9.1445},    
    pmid    = {15335312}        
    }
    @article{lin344018,
    title   = {Molecular cloning and characterization of a 2-deoxystreptamine biosynthetic gene cluster in gentamicin-producing Micromonospora echinospora ATCC15835.},    
    author  = {Kharel MK, Basnet DB, Lee HC, Liou K, Moon YH, Kim JJ, Woo JS, Sohng JK.},    
    journal = {Mol Cells},    
    year    = {2004},    
    doi     = {10.1016/s1016-8478(23)13083-4},    
    pmid    = {15359126}        
    }
    @article{lin344021,
    title   = {Gene cluster in Micromonospora echinospora ATCC15835 for the biosynthesis of the gentamicin C complex.},    
    author  = {Unwin J, Standage S, Alexander D, Hosted T, Horan AC, Wellington EM.},    
    journal = {J Antibiot (Tokyo)},    
    year    = {2004},    
    doi     = {10.7164/antibiotics.57.436},    
    pmid    = {15376556}        
    }
    @article{lin19559,
    title   = {Modulation of glycogen and trehalose levels in Micromonospora echinospora (ATCC 15837).},    
    author  = {Hoskisson PA, England R, Sharples GP, Hobbs G},    
    journal = {Antonie Van Leeuwenhoek},    
    year    = {2004},    
    doi     = {10.1023/B:ANTO.0000047920.48459.63},    
    pmid    = {15539926}        
    }
    @article{lin19558,
    title   = {Differentiation and protease production in Micromonospora echinospora (ATCC 15837).},    
    author  = {Hoskisson PA, Sharples GP, Hobbs G},    
    journal = {Antonie Van Leeuwenhoek},    
    year    = {2005},    
    doi     = {10.1007/s10482-005-9001-6},    
    pmid    = {16328864}        
    }
    @article{lin344011,
    title   = {Optimization of critical medium components for the maximal production of gentamicin by Micromonospora echinospora ATCC 15838 using response surface methodology.},    
    author  = {Himabindu M, Ravichandra P, Vishalakshi K, Jetty A.},    
    journal = {Appl Biochem Biotechnol},    
    year    = {2006},    
    doi     = {10.1385/abab:134:2:143},    
    pmid    = {16943635}        
    }
    @article{lin344008,
    title   = {Optimization of nutritional requirements for gentamicin production by Micromonospora echinospora.},    
    author  = {Himabindu M, Jetty A.},    
    journal = {Indian J Exp Biol},    
    year    = {2006},    
        
    pmid    = {17131916}        
    }
    @article{lin344012,
    title   = {Analytical profiling of biosynthetic intermediates involved in the gentamicin pathway of Micromonospora echinospora by high-performance liquid chromatography using electrospray ionization mass spectrometric detection.},    
    author  = {Park JW, Hong JS, Parajuli N, Koh HS, Park SR, Lee MO, Lim SK, Yoon YJ.},    
    journal = {Anal Chem},    
    year    = {2007},    
    doi     = {10.1021/ac070028u},    
    pmid    = {17521166}        
    }
    @article{lin344005,
    title   = {Gentamicin production by Micromonospora echinospora (Me- 22) in stirred tank reactor: effect of various parameters.},    
    author  = {Meenavilli H, Potumarthi R, Jetty A.},    
    journal = {J Basic Microbiol},    
    year    = {2008},    
    doi     = {10.1002/jobm.200700116},    
    pmid    = {18247396}        
    }
    @article{lin344016,
    title   = {Gene inactivation study of gntE reveals its role in the first step of pseudotrisaccharide modifications in gentamicin biosynthesis.},    
    author  = {Kim JY, Suh JW, Kang SH, Phan TH, Park SH, Kwon HJ.},    
    journal = {Biochem Biophys Res Commun},    
    year    = {2008},    
    doi     = {10.1016/j.bbrc.2008.05.133},    
    pmid    = {18533111}        
    }
    @article{lin344060,
    title   = {Genetic dissection of the biosynthetic route to gentamicin A2 by heterologous expression of its minimal gene set.},    
    author  = {Park JW, Hong JS, Parajuli N, Jung WS, Park SR, Lim SK, Sohng JK, Yoon YJ.},    
    journal = {Proc Natl Acad Sci U S A},    
    year    = {2008},    
    doi     = {10.1073/pnas.0803164105},    
    pmid    = {18550838}        
    }
    @article{lin344068,
    title   = {Microbial community analysis of field-grown soybeans with different nodulation phenotypes.},    
    author  = {Ikeda S, Rallos LE, Okubo T, Eda S, Inaba S, Mitsui H, Minamisawa K.},    
    journal = {Appl Environ Microbiol},    
    year    = {2008},    
    doi     = {10.1128/aem.00833-08},    
    pmid    = {18658280}        
    }
    @article{lin344091,
    title   = {Biochemical and structural insights of the early glycosylation steps in calicheamicin biosynthesis.},    
    author  = {Zhang C, Bitto E, Goff RD, Singh S, Bingman CA, Griffith BR, Albermann C, Phillips GN, Thorson JS.},    
    journal = {Chem Biol},    
    year    = {2008},    
    doi     = {10.1016/j.chembiol.2008.06.011},    
    pmid    = {18721755}        
    }
    @article{lin344062,
    title   = {The Bet v 1 fold: an ancient, versatile scaffold for binding of large, hydrophobic ligands.},    
    author  = {Radauer C, Lackner P, Breiteneder H.},    
    journal = {BMC Evol Biol},    
    year    = {2008},    
    doi     = {10.1186/1471-2148-8-286},    
    pmid    = {18922149}        
    }
    @article{lin344063,
    title   = {Determination of the target nucleosides for members of two families of 16S rRNA methyltransferases that confer resistance to partially overlapping groups of aminoglycoside antibiotics.},    
    author  = {Savic M, Lovric J, Tomic TI, Vasiljevic B, Conn GL.},    
    journal = {Nucleic Acids Res},    
    year    = {2009},    
    doi     = {10.1093/nar/gkp575},    
    pmid    = {19589804}        
    }
    @article{lin19557,
    title   = {Micromonospora tulbaghiae sp. nov., isolated from the leaves of wild garlic, Tulbaghia violacea.},    
    author  = {Kirby BM, Meyers PR},    
    journal = {Int J Syst Evol Microbiol},    
    year    = {2009},    
    doi     = {10.1099/ijs.0.013243-0},    
    pmid    = {19667372}        
    }
    @article{lin344014,
    title   = {TLN-05220, TLN-05223, new Echinosporamicin-type antibiotics, and proposed revision of the structure of bravomicins(*).},    
    author  = {Banskota AH, Aouidate M, Sorensen D, Ibrahim A, Piraee M, Zazopoulos E, Alarco AM, Gourdeau H, Mellon C, Farnet CM, Falardeau P, McAlpine JB.},    
    journal = {J Antibiot (Tokyo)},    
    year    = {2009},    
    doi     = {10.1038/ja.2009.77},    
    pmid    = {19680283}        
    }
    @article{lin344097,
    title   = {Formation and attachment of the deoxysugar moiety and assembly of the gene cluster for caprazamycin biosynthesis.},    
    author  = {Kaysser L, Wemakor E, Siebenberg S, Salas JA, Sohng JK, Kammerer B, Gust B.},    
    journal = {Appl Environ Microbiol},    
    year    = {2010},    
    doi     = {10.1128/aem.02740-09},    
    pmid    = {20418426}        
    }
    @article{lin344086,
    title   = {Polyketide synthase chemistry does not direct biosynthetic divergence between 9- and 10-membered enediynes.},    
    author  = {Horsman GP, Chen Y, Thorson JS, Shen B.},    
    journal = {Proc Natl Acad Sci U S A},    
    year    = {2010},    
    doi     = {10.1073/pnas.1003442107},    
    pmid    = {20534556}        
    }
    @article{lin344075,
    title   = {Structural characterization of CalO1: a putative orsellinic acid methyltransferase in the calicheamicin-biosynthetic pathway.},    
    author  = {Chang A, Singh S, Bingman CA, Thorson JS, Phillips GN.},    
    journal = {Acta Crystallogr D Biol Crystallogr},    
    year    = {2011},    
    doi     = {10.1107/s090744491100360x},    
    pmid    = {21358050}        
    }
    @article{lin344058,
    title   = {Solution structures of the acyl carrier protein domain from the highly reducing type I iterative polyketide synthase CalE8.},    
    author  = {Lim J, Kong R, Murugan E, Ho CL, Liang ZX, Yang D.},    
    journal = {PLoS One},    
    year    = {2011},    
    doi     = {10.1371/journal.pone.0020549},    
    pmid    = {21674045}        
    }
    @article{lin344090,
    title   = {New target for inhibition of bacterial RNA polymerase: 'switch region'.},    
    author  = {Srivastava A, Talaue M, Liu S, Degen D, Ebright RY, Sineva E, Chakraborty A, Druzhinin SY, Chatterjee S, Mukhopadhyay J, Ebright YW, Zozula A, Shen J, Sengupta S, Niedfeldt RR, Xin C, Kaneko T, Irschik H, Jansen R, Donadio S, Connell N, Ebright RH.},    
    journal = {Curr Opin Microbiol},    
    year    = {2011},    
    doi     = {10.1016/j.mib.2011.07.030},    
    pmid    = {21862392}        
    }
    @article{lin344096,
    title   = {Radical SAM enzymes in the biosynthesis of sugar-containing natural products.},    
    author  = {Ruszczycky MW, Ogasawara Y, Liu HW.},    
    journal = {Biochim Biophys Acta},    
    year    = {2012},    
    doi     = {10.1016/j.bbapap.2011.11.006},    
    pmid    = {22172915}        
    }
    @article{lin344101,
    title   = {Detection of transcriptional triggers in the dynamics of microbial growth: application to the respiratorily versatile bacterium Shewanella oneidensis.},    
    author  = {Beg QK, Zampieri M, Klitgord N, Collins SB, Altafini C, Serres MH, Segre D.},    
    journal = {Nucleic Acids Res},    
    year    = {2012},    
    doi     = {10.1093/nar/gks467},    
    pmid    = {22638572}        
    }
    @article{lin344036,
    title   = {Rigidifying acyl carrier protein domain in iterative type I PKS CalE8 does not affect its function.},    
    author  = {Lim J, Sun H, Fan JS, Hameed IF, Lescar J, Liang ZX, Yang D.},    
    journal = {Biophys J},    
    year    = {2012},    
    doi     = {10.1016/j.bpj.2012.08.006},    
    pmid    = {23009853}        
    }
    @article{lin344071,
    title   = {Feasibility of allografting in patients with advanced acute lymphoblastic leukemia after salvage therapy with inotuzumab ozogamicin.},    
    author  = {Kebriaei P, Wilhelm K, Ravandi F, Brandt M, de Lima M, Ciurea S, Worth L, O'Brien S, Thomas D, Champlin RE, Kantarjian H.},    
    journal = {Clin Lymphoma Myeloma Leuk},    
    year    = {2013},    
    doi     = {10.1016/j.clml.2012.12.003},    
    pmid    = {23313065}        
    }
    @article{lin343997,
    title   = {Characterization of a key aminoglycoside phosphotransferase in gentamicin biosynthesis.},    
    author  = {Shao L, Chen J, Wang C, Li JA, Tang Y, Chen D, Liu W.},    
    journal = {Bioorg Med Chem Lett},    
    year    = {2013},    
    doi     = {10.1016/j.bmcl.2012.12.064},    
    pmid    = {23339967}        
    }
    @article{lin344074,
    title   = {Novel therapeutic strategies in adult acute lymphoblastic leukemia--a focus on emerging monoclonal antibodies.},    
    author  = {Daver N, O'Brien S.},    
    journal = {Curr Hematol Malig Rep},    
    year    = {2013},    
    doi     = {10.1007/s11899-013-0160-7},    
    pmid    = {23539383}        
    }
    @article{lin344067,
    title   = {Results of inotuzumab ozogamicin, a CD22 monoclonal antibody, in refractory and relapsed acute lymphocytic leukemia.},    
    author  = {Kantarjian H, Thomas D, Jorgensen J, Kebriaei P, Jabbour E, Rytting M, York S, Ravandi F, Garris R, Kwari M, Faderl S, Cortes J, Champlin R, O'Brien S.},    
    journal = {Cancer},    
    year    = {2013},    
    doi     = {10.1002/cncr.28136},    
    pmid    = {23633004}        
    }
    @article{lin344094,
    title   = {Linked-in: design and efficacy of antibody drug conjugates in oncology.},    
    author  = {Feld J, Barta SK, Schinke C, Braunschweig I, Zhou Y, Verma AK.},    
    journal = {Oncotarget},    
    year    = {2013},    
    doi     = {10.18632/oncotarget.924},    
    pmid    = {23651630}        
    }
    @article{lin344038,
    title   = {Structural and functional characterization of CalS11, a TDP-rhamnose 3'-O-methyltransferase involved in calicheamicin biosynthesis.},    
    author  = {Singh S, Chang A, Helmich KE, Bingman CA, Wrobel RL, Beebe ET, Makino S, Aceti DJ, Dyer K, Hura GL, Sunkara M, Morris AJ, Phillips GN, Thorson JS.},    
    journal = {ACS Chem Biol},    
    year    = {2013},    
    doi     = {10.1021/cb400068k},    
    pmid    = {23662776}        
    }
    @article{lin344051,
    title   = {Halogenated volatiles from the fungus Geniculosporium and the actinomycete Streptomyces chartreusis.},    
    author  = {Wang T, Rabe P, Citron CA, Dickschat JS.},    
    journal = {Beilstein J Org Chem},    
    year    = {2013},    
    doi     = {10.3762/bjoc.9.311},    
    pmid    = {24367440}        
    }
    @article{lin343992,
    title   = {An off-pathway folding intermediate of an acyl carrier protein domain coexists with the folded and unfolded states under native conditions.},    
    author  = {Lim J, Xiao T, Fan J, Yang D.},    
    journal = {Angew Chem Int Ed Engl},    
    year    = {2014},    
    doi     = {10.1002/anie.201308512},    
    pmid    = {24470381}        
    }
    @article{lin344037,
    title   = {Specificity and promiscuity at the branch point in gentamicin biosynthesis.},    
    author  = {Guo J, Huang F, Huang C, Duan X, Jian X, Leeper F, Deng Z, Leadlay PF, Sun Y.},    
    journal = {Chem Biol},    
    year    = {2014},    
    doi     = {10.1016/j.chembiol.2014.03.005},    
    pmid    = {24746560}        
    }
    @article{lin343990,
    title   = {Genetic engineering combined with random mutagenesis to enhance G418 production in Micromonospora echinospora.},    
    author  = {Ni X, Sun Z, Zhang H, He H, Ji Z, Xia H.},    
    journal = {J Ind Microbiol Biotechnol},    
    year    = {2014},    
    doi     = {10.1007/s10295-014-1479-3},    
    pmid    = {25031027}        
    }
    @article{lin343993,
    title   = {Deoxyribonuclease inhibitors.},    
    author  = {Kolarevic A, Yancheva D, Kocic G, Smelcerovic A.},    
    journal = {Eur J Med Chem},    
    year    = {2014},    
    doi     = {10.1016/j.ejmech.2014.07.040},    
    pmid    = {25042005}        
    }
    @article{lin344039,
    title   = {Purification, crystallization and preliminary X-ray crystallographic analysis of glycosyltransferase-1 from Bacillus cereus.},    
    author  = {Hsieh YC, Chiu HH, Huang YC, Fun HK, Lu CY, Li YK, Chen CJ.},    
    journal = {Acta Crystallogr F Struct Biol Commun},    
    year    = {2014},    
    doi     = {10.1107/s2053230x14014629},    
    pmid    = {25195897}        
    }
    @article{lin344061,
    title   = {Successive nonstatistical and statistical approaches for the improved antibiotic activity of rare actinomycete Nonomuraea sp. JAJ18.},    
    author  = {Arul Jose P, Jebakumar SR.},    
    journal = {Biomed Res Int},    
    year    = {2014},    
    doi     = {10.1155/2014/906097},    
    pmid    = {25276828}        
    }
    @article{lin343985,
    title   = {Identification and characterization of a methionine gamma-lyase in the calicheamicin biosynthetic cluster of Micromonospora echinospora.},    
    author  = {Song H, Xu R, Guo Z.},    
    journal = {Chembiochem},    
    year    = {2015},    
    doi     = {10.1002/cbic.201402489},    
    pmid    = {25404066}        
    }
    @article{lin344047,
    title   = {Prognostic factors for outcome in patients with refractory and relapsed acute lymphocytic leukemia treated with inotuzumab ozogamicin, a CD22 monoclonal antibody.},    
    author  = {Jabbour E, O'Brien S, Huang X, Thomas D, Rytting M, Sasaki K, Cortes J, Garcia-Manero G, Kadia T, Ravandi F, Pierce S, Kantarjian H.},    
    journal = {Am J Hematol},    
    year    = {2015},    
    doi     = {10.1002/ajh.23901},    
    pmid    = {25407953}        
    }
    @article{lin344055,
    title   = {Delineating the biosynthesis of gentamicin x2, the common precursor of the gentamicin C antibiotic complex.},    
    author  = {Huang C, Huang F, Moison E, Guo J, Jian X, Duan X, Deng Z, Leadlay PF, Sun Y.},    
    journal = {Chem Biol},    
    year    = {2015},    
    doi     = {10.1016/j.chembiol.2014.12.012},    
    pmid    = {25641167}        
    }
    @article{lin344040,
    title   = {Structural Basis for the Stereochemical Control of Amine Installation in Nucleotide Sugar Aminotransferases.},    
    author  = {Wang F, Singh S, Xu W, Helmich KE, Miller MD, Cao H, Bingman CA, Thorson JS, Phillips GN.},    
    journal = {ACS Chem Biol},    
    year    = {2015},    
    doi     = {10.1021/acschembio.5b00244},    
    pmid    = {26023720}        
    }
    @article{lin344030,
    title   = {Crystal structure of O-methyltransferase CalO6 from the calicheamicin biosynthetic pathway: a case of challenging structure determination at low resolution.},    
    author  = {Tsodikov OV, Hou C, Walsh CT, Garneau-Tsodikova S.},    
    journal = {BMC Struct Biol},    
    year    = {2015},    
    doi     = {10.1186/s12900-015-0040-6},    
    pmid    = {26170207}        
    }
    @article{lin344082,
    title   = {Structural Characterization of CalS8, a TDP-alpha-D-Glucose Dehydrogenase Involved in Calicheamicin Aminodideoxypentose Biosynthesis.},    
    author  = {Singh S, Michalska K, Bigelow L, Endres M, Kharel MK, Babnigg G, Yennamalli RM, Bingman CA, Joachimiak A, Thorson JS, Phillips GN.},    
    journal = {J Biol Chem},    
    year    = {2015},    
    doi     = {10.1074/jbc.m115.673459},    
    pmid    = {26240141}        
    }
    @article{lin344083,
    title   = {C-S bond cleavage by a polyketide synthase domain.},    
    author  = {Ma M, Lohman JR, Liu T, Shen B.},    
    journal = {Proc Natl Acad Sci U S A},    
    year    = {2015},    
    doi     = {10.1073/pnas.1508437112},    
    pmid    = {26240335}        
    }
    @article{lin344031,
    title   = {Genome neighborhood network reveals insights into enediyne biosynthesis and facilitates prediction and prioritization for discovery.},    
    author  = {Rudolf JD, Yan X, Shen B.},    
    journal = {J Ind Microbiol Biotechnol},    
    year    = {2016},    
    doi     = {10.1007/s10295-015-1671-0},    
    pmid    = {26318027}        
    }
    @article{lin185524,
    title   = {Induced systemic resistance against Botrytis cinerea by Micromonospora strains isolated from root nodules.},    
    author  = {Martinez-Hidalgo P, Garcia JM, Pozo MJ.},    
    journal = {Front Microbiol},    
    year    = {2015},    
    doi     = {10.3389/fmicb.2015.00922},    
    pmid    = {26388861}        
    }
    @article{lin344099,
    title   = {Recent Advances in the Development of Antineoplastic Agents Derived from Natural Products.},    
    author  = {Trendowski M.},    
    journal = {Drugs},    
    year    = {2015},    
    doi     = {10.1007/s40265-015-0489-4},    
    pmid    = {26501980}        
    }
    @article{lin344001,
    title   = {Assembly of a novel biosynthetic pathway for gentamicin B production in Micromonospora echinospora.},    
    author  = {Ni X, Sun Z, Gu Y, Cui H, Xia H.},    
    journal = {Microb Cell Fact},    
    year    = {2016},    
    doi     = {10.1186/s12934-015-0402-6},    
    pmid    = {26729212}        
    }
    @article{lin344093,
    title   = {Structural and kinetic studies on RosA, the enzyme catalysing the methylation of 8-demethyl-8-amino-d-riboflavin to the antibiotic roseoflavin.},    
    author  = {Tongsook C, Uhl MK, Jankowitsch F, Mack M, Gruber K, Macheroux P.},    
    journal = {FEBS J},    
    year    = {2016},    
    doi     = {10.1111/febs.13690},    
    pmid    = {26913589}        
    }
    @article{lin344041,
    title   = {Loop dynamics of thymidine diphosphate-rhamnose 3'-O-methyltransferase (CalS11), an enzyme in calicheamicin biosynthesis.},    
    author  = {Han L, Singh S, Thorson JS, Phillips GN.},    
    journal = {Struct Dyn},    
    year    = {2016},    
    doi     = {10.1063/1.4941368},    
    pmid    = {26958582}        
    }
    @article{lin344015,
    title   = {Structural dynamics of a methionine gamma-lyase for calicheamicin biosynthesis: Rotation of the conserved tyrosine stacking with pyridoxal phosphate.},    
    author  = {Cao H, Tan K, Wang F, Bigelow L, Yennamalli RM, Jedrzejczak R, Babnigg G, Bingman CA, Joachimiak A, Kharel MK, Singh S, Thorson JS, Phillips GN.},    
    journal = {Struct Dyn},    
    year    = {2016},    
    doi     = {10.1063/1.4948539},    
    pmid    = {27191010}        
    }
    @article{lin344079,
    title   = {Antibody Based Therapies in Acute Leukemia.},    
    author  = {Shah NN.},    
    journal = {Curr Drug Targets},    
    year    = {2017},    
    doi     = {10.2174/1389450117666160905091459},    
    pmid    = {27593687}        
    }
    @article{lin344098,
    title   = {The ClusPro web server for protein-protein docking.},    
    author  = {Kozakov D, Hall DR, Xia B, Porter KA, Padhorny D, Yueh C, Beglov D, Vajda S.},    
    journal = {Nat Protoc},    
    year    = {2017},    
    doi     = {10.1038/nprot.2016.169},    
    pmid    = {28079879}        
    }
    @article{lin344023,
    title   = {Final Demonstration of the Co-Identity of Lipiarmycin A3 and Tiacumicin B (Fidaxomicin) through Single Crystal X-ray Analysis.},    
    author  = {Serra S, Malpezzi L, Bedeschi A, Fuganti C, Fonte P.},    
    journal = {Antibiotics (Basel)},    
    year    = {2017},    
    doi     = {10.3390/antibiotics6010007},    
    pmid    = {28208717}        
    }
    @article{lin343987,
    title   = {Long-Chain Alkyl Cyanides: Unprecedented Volatile Compounds Released by Pseudomonas and Micromonospora Bacteria.},    
    author  = {Montes Vidal D, von Rymon-Lipinski AL, Ravella S, Groenhagen U, Herrmann J, Zaburannyi N, Zarbin PH, Varadarajan AR, Ahrens CH, Weisskopf L, Muller R, Schulz S.},    
    journal = {Angew Chem Int Ed Engl},    
    year    = {2017},    
    doi     = {10.1002/anie.201611940},    
    pmid    = {28276609}        
    }
    @article{lin344029,
    title   = {Structural and mechanistic insights into homocysteine degradation by a mutant of methionine gamma-lyase based on substrate-assisted catalysis.},    
    author  = {Sato D, Shiba T, Yunoto S, Furutani K, Fukumoto M, Kudou D, Tamura T, Inagaki K, Harada S.},    
    journal = {Protein Sci},    
    year    = {2017},    
    doi     = {10.1002/pro.3158},    
    pmid    = {28329912}        
    }
    @article{lin344049,
    title   = {Mining of efficient microbial UDP-glycosyltransferases by motif evolution cross plant kingdom for application in biosynthesis of salidroside.},    
    author  = {Fan B, Chen T, Zhang S, Wu B, He B.},    
    journal = {Sci Rep},    
    year    = {2017},    
    doi     = {10.1038/s41598-017-00568-z},    
    pmid    = {28352078}        
    }
    @article{lin344085,
    title   = {DNAproDB: an interactive tool for structural analysis of DNA-protein complexes.},    
    author  = {Sagendorf JM, Berman HM, Rohs R.},    
    journal = {Nucleic Acids Res},    
    year    = {2017},    
    doi     = {10.1093/nar/gkx272},    
    pmid    = {28431131}        
    }
    @article{lin344070,
    title   = {X-Ray snapshots of a pyridoxal enzyme: a catalytic mechanism involving concerted [1,5]-hydrogen sigmatropy in methionine gamma-lyase.},    
    author  = {Sato D, Shiba T, Karaki T, Yamagata W, Nozaki T, Nakazawa T, Harada S.},    
    journal = {Sci Rep},    
    year    = {2017},    
    doi     = {10.1038/s41598-017-05032-6},    
    pmid    = {28687762}        
    }
    @article{lin343986,
    title   = {Structural Basis of the Selectivity of GenN, an Aminoglycoside N-Methyltransferase Involved in Gentamicin Biosynthesis.},    
    author  = {Bury PDS, Huang F, Li S, Sun Y, Sun Y, Leadlay PF, Dias MVB.},    
    journal = {ACS Chem Biol},    
    year    = {2017},    
    doi     = {10.1021/acschembio.7b00466},    
    pmid    = {28876898}        
    }
    @article{lin344002,
    title   = {Equilibrium folding dynamics of meACP in water, heavy water, and low concentration of urea.},    
    author  = {Zhou Y, Yang D.},    
    journal = {Sci Rep},    
    year    = {2017},    
    doi     = {10.1038/s41598-017-16449-4},    
    pmid    = {29170533}        
    }
    @article{lin344078,
    title   = {Molecular characterization of a Rhodococcus jostii RHA1 gamma-butyrolactone(-like) signalling molecule and its main biosynthesis gene gblA.},    
    author  = {Ceniceros A, Dijkhuizen L, Petrusma M.},    
    journal = {Sci Rep},    
    year    = {2017},    
    doi     = {10.1038/s41598-017-17853-6},    
    pmid    = {29255143}        
    }
    @article{lin344048,
    title   = {Potential of rare actinomycetes in the production of metabolites against multiple oxidant agents.},    
    author  = {Mohammadipanah F, Momenilandi M.},    
    journal = {Pharm Biol},    
    year    = {2018},    
    doi     = {10.1080/13880209.2017.1417451},    
    pmid    = {29275696}        
    }
    @article{lin344087,
    title   = {Enhanced Solubilization of Class B Radical S-Adenosylmethionine Methylases by Improved Cobalamin Uptake in Escherichia coli.},    
    author  = {Lanz ND, Blaszczyk AJ, McCarthy EL, Wang B, Wang RX, Jones BS, Booker SJ.},    
    journal = {Biochemistry},    
    year    = {2018},    
    doi     = {10.1021/acs.biochem.7b01205},    
    pmid    = {29298049}        
    }
    @article{lin344095,
    title   = {Genome-based classification of micromonosporae with a focus on their biotechnological and ecological potential.},    
    author  = {Carro L, Nouioui I, Sangal V, Meier-Kolthoff JP, Trujillo ME, Montero-Calasanz MDC, Sahin N, Smith DL, Kim KE, Peluso P, Deshpande S, Woyke T, Shapiro N, Kyrpides NC, Klenk HP, Goker M, Goodfellow M.},    
    journal = {Sci Rep},    
    year    = {2018},    
    doi     = {10.1038/s41598-017-17392-0},    
    pmid    = {29323202}        
    }
    @article{lin343999,
    title   = {Methyltransferases of gentamicin biosynthesis.},    
    author  = {Li S, Guo J, Reva A, Huang F, Xiong B, Liu Y, Deng Z, Leadlay PF, Sun Y.},    
    journal = {Proc Natl Acad Sci U S A},    
    year    = {2018},    
    doi     = {10.1073/pnas.1711603115},    
    pmid    = {29358400}        
    }
    @article{lin344054,
    title   = {The impact of storage conditions upon gentamicin coated antimicrobial implants.},    
    author  = {Mullins ND, Deadman BJ, Moynihan HA, McCarthy FO, Lawrence SE, Thompson J, Maguire AR.},    
    journal = {J Pharm Anal},    
    year    = {2016},    
    doi     = {10.1016/j.jpha.2016.05.002},    
    pmid    = {29404006}        
    }
    @article{lin344052,
    title   = {The three-dimensional structure of NeoB: An aminotransferase involved in the biosynthesis of neomycin.},    
    author  = {Dow GT, Thoden JB, Holden HM.},    
    journal = {Protein Sci},    
    year    = {2018},    
    doi     = {10.1002/pro.3400},    
    pmid    = {29516565}        
    }
    @article{lin344033,
    title   = {Establishment and characterization of a GES-1 human gastric epithelial cell line stably expressing miR-23a.},    
    author  = {Chen L, Gao Y, Zhu L, Song H, Zhao L, Liu A, Zhang G, Shi G.},    
    journal = {Oncol Lett},    
    year    = {2018},    
    doi     = {10.3892/ol.2018.8765},    
    pmid    = {29963172}        
    }
    @article{lin344072,
    title   = {Gemtuzumab ozogamicin for treatment of newly diagnosed CD33-positive acute myeloid leukemia.},    
    author  = {Gbadamosi M, Meshinchi S, Lamba JK.},    
    journal = {Future Oncol},    
    year    = {2018},    
    doi     = {10.2217/fon-2018-0325},    
    pmid    = {30039981}        
    }
    @article{lin344042,
    title   = {DNA damaging agent-based antibody-drug conjugates for cancer therapy.},    
    author  = {Fu Y, Ho M.},    
    journal = {Antib Ther},    
    year    = {2018},    
    doi     = {10.1093/abt/tby007},    
    pmid    = {30294716}        
    }
    @article{lin344020,
    title   = {Enhanced Biosynthesis of 2-Deoxy-<i>scyllo</i>-inosose in Metabolically Engineered <i>Bacillus subtilis</i> Recombinants.},    
    author  = {Lim JH, Hwang HH, Lee NJ, Lee JW, Seo EG, Son HB, Kim HJ, Yoon YJ, Park JW.},    
    journal = {Front Microbiol},    
    year    = {2018},    
    doi     = {10.3389/fmicb.2018.02333},    
    pmid    = {30319595}        
    }
    @article{lin344026,
    title   = {Complete reconstitution of the diverse pathways of gentamicin B biosynthesis.},    
    author  = {Ban YH, Song MC, Hwang JY, Shin HL, Kim HJ, Hong SK, Lee NJ, Park JW, Cha SS, Liu HW, Yoon YJ.},    
    journal = {Nat Chem Biol},    
    year    = {2019},    
    doi     = {10.1038/s41589-018-0203-4},    
    pmid    = {30643280}        
    }
    @article{lin344064,
    title   = {Rational Reprogramming of O-Methylation Regioselectivity for Combinatorial Biosynthetic Tailoring of Benzenediol Lactone Scaffolds.},    
    author  = {Wang X, Wang C, Duan L, Zhang L, Liu H, Xu YM, Liu Q, Mao T, Zhang W, Chen M, Lin M, Gunatilaka AAL, Xu Y, Molnar I.},    
    journal = {J Am Chem Soc},    
    year    = {2019},    
    doi     = {10.1021/jacs.8b12967},    
    pmid    = {30767524}        
    }
    @article{lin344081,
    title   = {Chk1 Inhibition Restores Inotuzumab Ozogamicin Citotoxicity in CD22-Positive Cells Expressing Mutant p53.},    
    author  = {Tirro E, Massimino M, Romano C, Pennisi MS, Stella S, Vitale SR, Fidilio A, Manzella L, Parrinello NL, Stagno F, Palumbo GA, La Cava P, Romano A, Di Raimondo F, Vigneri PG.},    
    journal = {Front Oncol},    
    year    = {2019},    
    doi     = {10.3389/fonc.2019.00057},    
    pmid    = {30834235}        
    }
    @article{lin185522,
    title   = {Discovery of novel carbohydrate-active enzymes through the rational exploration of the protein sequences space.},    
    author  = {Helbert W, Poulet L, Drouillard S, Mathieu S, Loiodice M, Couturier M, Lombard V, Terrapon N, Turchetto J, Vincentelli R, Henrissat B.},    
    journal = {Proc Natl Acad Sci U S A},    
    year    = {2019},    
    doi     = {10.1073/pnas.1815791116},    
    pmid    = {30850540}        
    }
    @article{lin344050,
    title   = {Novel monoclonal antibody-based treatment strategies in adults with acute lymphoblastic leukemia.},    
    author  = {Guerra VA, Jabbour EJ, Ravandi F, Kantarjian H, Short NJ.},    
    journal = {Ther Adv Hematol},    
    year    = {2019},    
    doi     = {10.1177/2040620719849496},    
    pmid    = {31205644}        
    }
    @article{lin344045,
    title   = {Bioactivities of Halometabolites from Marine Actinobacteria.},    
    author  = {Kasanah N, Triyanto T.},    
    journal = {Biomolecules},    
    year    = {2019},    
    doi     = {10.3390/biom9060225},    
    pmid    = {31212626}        
    }
    @article{lin344053,
    title   = {The Effect of Divalent Cations on the Thermostability of Type II Polyketide Synthase Acyl Carrier Proteins.},    
    author  = {Rivas M, Courouble VC, Baker MC, Cookmeyer DL, Fiore KE, Frost AJ, Godbe KN, Jordan MR, Krasnow EN, Mollo A, Ridings ST, Sawada K, Shroff KD, Studnitzer B, Thiele GAR, Sisto AC, Nawaal S, Huff AR, Fairman R, Johnson KA, Beld J, Kokona B, Charkoudian LK.},    
    journal = {AIChE J},    
    year    = {2018},    
    doi     = {10.1002/aic.16402},    
    pmid    = {31527922}        
    }
    @article{lin343988,
    title   = {Overproduction of gentamicin B in industrial strain <i>Micromonospora echinospora</i> CCTCC M 2018898 by cloning of the missing genes <i>genR</i> and <i>genS</i>.},    
    author  = {Chang Y, Chai B, Ding Y, He M, Zheng L, Teng Y, Deng Z, Yu Y, Liu T.},    
    journal = {Metab Eng Commun},    
    year    = {2019},    
    doi     = {10.1016/j.mec.2019.e00096},    
    pmid    = {31720212}        
    }
    @article{lin343989,
    title   = {Exclusive Production of Gentamicin C1a from <i>Micromonospora purpurea</i> by Metabolic Engineering.},    
    author  = {Wei Z, Shi X, Lian R, Wang W, Hong W, Guo S.},    
    journal = {Antibiotics (Basel)},    
    year    = {2019},    
    doi     = {10.3390/antibiotics8040267},    
    pmid    = {31847403}        
    }
    @article{lin185521,
    title   = {Comparative Genomic Analysis of Soil Dwelling Bacteria Utilizing a Combinational Codon Usage and Molecular Phylogenetic Approach Accentuating on Key Housekeeping Genes.},    
    author  = {Saha J, Saha BK, Pal Sarkar M, Roy V, Mandal P, Pal A.},    
    journal = {Front Microbiol},    
    year    = {2019},    
    doi     = {10.3389/fmicb.2019.02896},    
    pmid    = {31921071}        
    }
    @article{lin185519,
    title   = {Extending the Salinilactone Family.},    
    author  = {Schlawis C, Harig T, Ehlers S, Guillen-Matus DG, Creamer KE, Jensen PR, Schulz S.},    
    journal = {Chembiochem},    
    year    = {2020},    
    doi     = {10.1002/cbic.201900764},    
    pmid    = {31957947}        
    }
    @article{lin344046,
    title   = {Glycosylated Natural Products From Marine Microbes.},    
    author  = {Li K, Cai J, Su Z, Yang B, Liu Y, Zhou X, Huang J, Tao H.},    
    journal = {Front Chem},    
    year    = {2019},    
    doi     = {10.3389/fchem.2019.00879},    
    pmid    = {31998682}        
    }
    @article{lin343973,
    title   = {<i>S</i>-Bridged Thioether and Structure-Diversified Angucyclinone Derivatives from the South China Sea-Derived <i>Micromonospora echinospora</i> SCSIO 04089.},    
    author  = {Fang Z, Jiang X, Zhang Q, Zhang L, Zhang W, Yang C, Zhang H, Zhu Y, Zhang C.},    
    journal = {J Nat Prod},    
    year    = {2020},    
    doi     = {10.1021/acs.jnatprod.0c00719},    
    pmid    = {32970433}        
    }
    @article{lin344013,
    title   = {Pyridoxal-5'-phosphate-dependent enzyme GenB3 Catalyzes C-3',4'-dideoxygenation in gentamicin biosynthesis.},    
    author  = {Zhou S, Chen X, Ni X, Liu Y, Zhang H, Dong M, Xia H.},    
    journal = {Microb Cell Fact},    
    year    = {2021},    
    doi     = {10.1186/s12934-021-01558-7},    
    pmid    = {33750386}        
    }
    @article{lin344004,
    title   = {A thermostable glycosyltransferase from <i>Paenibacillus polymyxa</i> NJPI29: recombinant expression, characterization, and application in synthesis of glycosides.},    
    author  = {Chang S, Pan X, Zhao M, Li G, Wang X, Fan Y, Song W, Li B, Zhang S, He X.},    
    journal = {3 Biotech},    
    year    = {2021},    
    doi     = {10.1007/s13205-021-02855-z},    
    pmid    = {34109099}        
    }
    @article{lin344024,
    title   = {Microbial Enzymatic Synthesis of Amikacin Analogs With Antibacterial Activity Against Multidrug-Resistant Pathogens.},    
    author  = {Ban YH, Song MC, Jeong JH, Kwun MS, Kim CR, Ryu HS, Kim E, Park JW, Lee DG, Yoon YJ.},    
    journal = {Front Microbiol},    
    year    = {2021},    
    doi     = {10.3389/fmicb.2021.725916},    
    pmid    = {34512603}        
    }
    @article{lin344076,
    title   = {Rubber Degrading Strains: <i>Microtetraspora</i> and <i>Dactylosporangium</i>.},    
    author  = {Basik AA, Nanthini J, Yeo TC, Sudesh K.},    
    journal = {Polymers (Basel)},    
    year    = {2021},    
    doi     = {10.3390/polym13203524},    
    pmid    = {34685283}        
    }
    @article{lin343994,
    title   = {Controllable Iterative beta-Glucosylation from UDP-Glucose by <i>Bacillus cereus</i> Glycosyltransferase GT1: Application for the Synthesis of Disaccharide-Modified Xenobiotics.},    
    author  = {Jung J, Schachtschabel D, Speitling M, Nidetzky B.},    
    journal = {J Agric Food Chem},    
    year    = {2021},    
    doi     = {10.1021/acs.jafc.1c05788},    
    pmid    = {34817995}        
    }
    @article{lin343981,
    title   = {In Vitro Antitumor Activity of Endophytic and Rhizosphere Gram-Positive Bacteria from <i>Ibervillea sonorae</i> (S. Watson) Greene against L5178Y-R Lymphoma Cells.},    
    author  = {Romero-Arguelles R, Romo-Saenz CI, Moran-Santibanez K, Tamez-Guerra P, Quintanilla-Licea R, Orozco-Flores AA, Ramirez-Villalobos JM, Tamez-Guerra R, Rodriguez-Padilla C, Gomez-Flores R.},    
    journal = {Int J Environ Res Public Health},    
    year    = {2022},    
    doi     = {10.3390/ijerph19020894},    
    pmid    = {35055716}        
    }
    @article{lin344066,
    title   = {Pseudomonas aeruginosa cytochrome P450 CYP168A1 is a fatty acid hydroxylase that metabolizes arachidonic acid to the vasodilator 19-HETE.},    
    author  = {Tooker BC, Kandel SE, Work HM, Lampe JN.},    
    journal = {J Biol Chem},    
    year    = {2022},    
    doi     = {10.1016/j.jbc.2022.101629},    
    pmid    = {35085556}        
    }
    @article{lin343974,
    title   = {Glycosylation of Semi-Synthetic Isoflavene Phenoxodiol with a Recombinant Glycosyltransferase from <i>Micromonospora echinospora</i> ATCC 27932.},    
    author  = {Seo M, Seol Y, Park JW.},    
    journal = {J Microbiol Biotechnol},    
    year    = {2022},    
    doi     = {10.4014/jmb.2111.11032},    
    pmid    = {35131959}        
    }
    @article{lin344006,
    title   = {Mintaimycins, a Group of Novel Peptide Metabolites from <i>Micromonospora</i> sp. C-3509.},    
    author  = {Hu X, Wang Y, Zhao C, Li S, Hu X, You X, Shen J, Wang Z, Hong B, Jiang B, Du Y, Wu L.},    
    journal = {Molecules},    
    year    = {2022},    
    doi     = {10.3390/molecules27041150},    
    pmid    = {35208940}        
    }
    @article{lin344103,
    title   = {SDR enzymes oxidize specific lipidic alkynylcarbinols into cytotoxic protein-reactive species.},    
    author  = {Demange P, Joly E, Marcoux J, Zanon PRA, Listunov D, Rulliere P, Barthes C, Noirot C, Izquierdo JB, Rozie A, Pradines K, Hee R, de Brito MV, Marcellin M, Serre RF, Bouchez O, Burlet-Schiltz O, Oliveira MCF, Ballereau S, Bernardes-Genisson V, Maraval V, Calsou P, Hacker SM, Genisson Y, Chauvin R, Britton S.},    
    journal = {Elife},    
    year    = {2022},    
    doi     = {10.7554/elife.73913},    
    pmid    = {35535493}        
    }
    @article{lin343995,
    title   = {Characterization and utilization of methyltransferase for apramycin production in Streptoalloteichus tenebrarius.},    
    author  = {Sun J, Gao H, Yan D, Liu Y, Ni X, Xia H.},    
    journal = {J Ind Microbiol Biotechnol},    
    year    = {2022},    
    doi     = {10.1093/jimb/kuac011},    
    pmid    = {35536571}        
    }
    @article{lin344025,
    title   = {Elucidating the mechanisms underlying protein conformational switching using NMR spectroscopy.},    
    author  = {Jain S, Sekhar A.},    
    journal = {J Magn Reson Open},    
    year    = {2022},    
    doi     = {10.1016/j.jmro.2022.100034},    
    pmid    = {35586549}        
    }
    @article{lin344017,
    title   = {The Search for Cryptic L-Rhamnosyltransferases on the <i>Sporothrix schenckii</i> Genome.},    
    author  = {Mora-Montes HM, Garcia-Gutierrez K, Garcia-Carnero LC, Lozoya-Perez NE, Ramirez-Prado JH.},    
    journal = {J Fungi (Basel)},    
    year    = {2022},    
    doi     = {10.3390/jof8050529},    
    pmid    = {35628784}        
    }
    @article{lin344043,
    title   = {ABBV-011, A Novel, Calicheamicin-Based Antibody-Drug Conjugate, Targets SEZ6 to Eradicate Small Cell Lung Cancer Tumors.},    
    author  = {Wiedemeyer WR, Gavrilyuk J, Schammel A, Zhao X, Sarvaiya H, Pysz M, Gu C, You M, Isse K, Sullivan T, French D, Lee C, Dang AT, Zhang Z, Aujay M, Bankovich AJ, Vitorino P.},    
    journal = {Mol Cancer Ther},    
    year    = {2022},    
    doi     = {10.1158/1535-7163.mct-21-0851},    
    pmid    = {35642431}        
    }
    @article{lin343996,
    title   = {A Functional Carbohydrate Degrading Enzyme Potentially Acquired by Horizontal Gene Transfer in the Genome of the Soil Invertebrate <i>Folsomia candida</i>.},    
    author  = {Le NG, van Ulsen P, van Spanning R, Brouwer A, van Straalen NM, Roelofs D.},    
    journal = {Genes (Basel)},    
    year    = {2022},    
    doi     = {10.3390/genes13081402},    
    pmid    = {36011312}        
    }
    @article{lin185520,
    title   = {Furaquinocins K and L: Novel Naphthoquinone-Based Meroterpenoids from <i>Streptomyces</i> sp. Je 1-369.},    
    author  = {Tistechok S, Stierhof M, Myronovskyi M, Zapp J, Gromyko O, Luzhetskyy A.},    
    journal = {Antibiotics (Basel)},    
    year    = {2022},    
    doi     = {10.3390/antibiotics11111587},    
    pmid    = {36358243}        
    }
    @article{lin344000,
    title   = {Specialized Metabolism of Gordonia Genus: An Integrated Survey on Chemodiversity Combined with a Comparative Genomics-Based Analysis.},    
    author  = {Sanchez-Suarez J, Diaz L, Coy-Barrera E, Villamil L.},    
    journal = {BioTech (Basel)},    
    year    = {2022},    
    doi     = {10.3390/biotech11040053},    
    pmid    = {36412754}        
    }
    @article{lin344010,
    title   = {Volatiles of the Apicomplexan Alga Chromera velia and Associated Bacteria.},    
    author  = {Koteska D, Marter P, Huang S, Pradella S, Petersen J, Schulz S.},    
    journal = {Chembiochem},    
    year    = {2023},    
    doi     = {10.1002/cbic.202200530},    
    pmid    = {36416092}        
    }
    @article{lin344009,
    title   = {Application of a Biocatalytic Strategy for the Preparation of Tiancimycin-Based Antibody-Drug Conjugates Revealing Key Insights into Structure-Activity Relationships.},    
    author  = {Steele AD, Kiefer AF, Hwang D, Yang D, Teijaro CN, Adhikari A, Rader C, Shen B.},    
    journal = {J Med Chem},    
    year    = {2023},    
    doi     = {10.1021/acs.jmedchem.2c01771},    
    pmid    = {36599039}        
    }
    @article{lin344065,
    title   = {Antibody-drug conjugates for lymphoma patients: preclinical and clinical evidences.},    
    author  = {Barreca M, Lang N, Tarantelli C, Spriano F, Barraja P, Bertoni F.},    
    journal = {Explor Target Antitumor Ther},    
    year    = {2022},    
    doi     = {10.37349/etat.2022.00112},    
    pmid    = {36654819}        
    }
    @article{lin344019,
    title   = {Asymmetric Synthesis of US-FDA Approved Drugs over Five Years (2016-2020): A Recapitulation of Chirality.},    
    author  = {Tamatam R, Shin D.},    
    journal = {Pharmaceuticals (Basel)},    
    year    = {2023},    
    doi     = {10.3390/ph16030339},    
    pmid    = {36986439}        
    }
    @article{lin185523,
    title   = {Discovery and biosynthetic assessment of '<i>Streptomyces ortus'</i> sp. nov. isolated from a deep-sea sponge.},    
    author  = {Williams SE, Back CR, Best E, Mantell J, Stach JEM, Williams TA, Race PR, Curnow P.},    
    journal = {Microb Genom},    
    year    = {2023},    
    doi     = {10.1099/mgen.0.000996},    
    pmid    = {37166955}        
    }
    @article{lin344007,
    title   = {Enhancing the Antibiotic Production by Thermophilic Bacteria Isolated from Hot Spring Waters via Ethyl Methanesulfonate Mutagenesis.},    
    author  = {Kortam YG, Abd El-Rahim WM, Khattab AEA, Rebouh NY, Gurina RR, Barakat OS, Zakaria M, Moawad H.},    
    journal = {Antibiotics (Basel)},    
    year    = {2023},    
    doi     = {10.3390/antibiotics12071095},    
    pmid    = {37508191}        
    }
    @article{lin344035,
    title   = {Harnessing the Immune System: Current and Emerging Immunotherapy Strategies for Pediatric Acute Lymphoblastic Leukemia.},    
    author  = {Glasser CL, Chen J.},    
    journal = {Biomedicines},    
    year    = {2023},    
    doi     = {10.3390/biomedicines11071886},    
    pmid    = {37509525}        
    }
    @article{lin343998,
    title   = {aMeta: an accurate and memory-efficient ancient metagenomic profiling workflow.},    
    author  = {Pochon Z, Bergfeldt N, Kirdok E, Vicente M, Naidoo T, van der Valk T, Altinisik NE, Krzewinska M, Dalen L, Gotherstrom A, Mirabello C, Unneberg P, Oskolkov N.},    
    journal = {Genome Biol},    
    year    = {2023},    
    doi     = {10.1186/s13059-023-03083-9},    
    pmid    = {37872569}        
    }
    @article{lin344088,
    title   = {Drug conjugates for the treatment of lung cancer: from drug discovery to clinical practice.},    
    author  = {Zhou L, Lu Y, Liu W, Wang S, Wang L, Zheng P, Zi G, Liu H, Liu W, Wei S.},    
    journal = {Exp Hematol Oncol},    
    year    = {2024},    
    doi     = {10.1186/s40164-024-00493-8},    
    pmid    = {38429828}        
    }
    @article{lin343980,
    title   = {From Natural Microbe Screening to Sustained Chitinase Activity in Exogenous Hosts.},    
    author  = {Chaulagain D, Shamabadi NS, Leslie SA, Karig DK.},    
    journal = {ACS Synth Biol},    
    year    = {2024},    
    doi     = {10.1021/acssynbio.3c00637},    
    pmid    = {38587290}        
    }
    @article{lin185517,
    title   = {<i>Micromonospora cathayae</i> sp. nov., isolated from the rhizosphere soil of <i>Cathaya argyrophylla</i>.},    
    author  = {Long PL, Fu L, Xiao Y, Gao J.},    
    journal = {Int J Syst Evol Microbiol},    
    year    = {2024},    
    doi     = {10.1099/ijsem.0.006332},    
    pmid    = {38602173}        
    }
    @article{lin343978,
    title   = {Enediyne natural product biosynthesis unified by a diiodotetrayne intermediate.},    
    author  = {Gui C, Kalkreuter E, Lauterbach L, Yang D, Shen B.},    
    journal = {Nat Chem Biol},    
    year    = {2024},    
    doi     = {10.1038/s41589-024-01636-y},    
    pmid    = {38831037}        
    }
    @article{lin343975,
    title   = {Stepwise increase of fidaxomicin in an engineered heterologous host <i>Streptomyces albus</i> through multi-level metabolic engineering.},    
    author  = {Xie H, Su YT, Bu QT, Li YP, Zhao QW, Du YL, Li YQ.},    
    journal = {Synth Syst Biotechnol},    
    year    = {2024},    
    doi     = {10.1016/j.synbio.2024.06.004},    
    pmid    = {39021363}        
    }
    @article{lin343982,
    title   = {Biosynthesis of the Unusual Epoxy Isonitrile-Containing Antibiotics Aerocyanidin and Amycomicin.},    
    author  = {Zheng Z, Clardy J, Liu HW.},    
    journal = {J Am Chem Soc},    
    year    = {2024},    
    doi     = {10.1021/jacs.4c06411},    
    pmid    = {39039999}        
    }
    @article{lin343991,
    title   = {Structural and Functional Basis of GenB2 Isomerase Activity from Gentamicin Biosynthesis.},    
    author  = {Oliveira GS, Dos S Bury P, Huang F, Li Y, Araujo NC, Zhou J, Sun Y, Leeper FJ, Leadlay PF, Dias MVB.},    
    journal = {ACS Chem Biol},    
    year    = {2024},    
    doi     = {10.1021/acschembio.4c00334},    
    pmid    = {39207862}        
    }
    @article{lin344003,
    title   = {Glycodiversification of gentamicins through <i>in vivo</i> glycosyltransferase swapping enabled the creation of novel hybrid aminoglycoside antibiotics with potent activity and low ototoxicity.},    
    author  = {Jian X, Wang C, Wu S, Sun G, Huang C, Qiu C, Liu Y, Leadlay PF, Liu D, Deng Z, Zhou F, Sun Y.},    
    journal = {Acta Pharm Sin B},    
    year    = {2024},    
    doi     = {10.1016/j.apsb.2024.04.030},    
    pmid    = {39309510}        
    }
    @article{lin343984,
    title   = {Niche-Aware Metagenomic Screening for Enzyme Methioninase Illuminates Its Contribution to Metabolic Syntrophy.},    
    author  = {Khamespanah E, Asad S, Vanak Z, Mehrshad M.},    
    journal = {Microb Ecol},    
    year    = {2024},    
    doi     = {10.1007/s00248-024-02458-0},    
    pmid    = {39546027}        
    }
    @article{lin344022,
    title   = {Recent advances in the biosynthesis and production optimization of gentamicin: A critical review.},    
    author  = {Xu F, Hu K, Mohsin A, Wu J, Su L, Wang Y, Ben R, Gao H, Tian X, Chu J.},    
    journal = {Synth Syst Biotechnol},    
    year    = {2025},    
    doi     = {10.1016/j.synbio.2024.11.003},    
    pmid    = {39640289}        
    }
    @article{lin343976,
    title   = {GC/MS Fatty Acid Profile of Marine-Derived Actinomycetes from Extreme Environments: Chemotaxonomic Insights and Biotechnological Potential.},    
    author  = {Cunha MB, Jorge AF, Nunes MJ, Sousa JR, Lanca MJ, Gomes da Silva M, Gaudencio SP.},    
    journal = {Mar Drugs},    
    year    = {2024},    
    doi     = {10.3390/md23010001},    
    pmid    = {39852503}        
    }
    @article{lin185525,
    title   = {Taxonomic description of <i>Micromonospora reichwaldensis</i> sp. nov. and its biosynthetic and plant growth-promoting potential.},    
    author  = {Nouioui I, Zimmermann A, Gomez Escribano JP, Jando M, Potter G, Neumann-Schaal M, Mast Y.},    
    journal = {Microbiol Spectr},    
    year    = {2025},    
    doi     = {10.1128/spectrum.02129-24},    
    pmid    = {40029309}        
    }
    @article{lin185518,
    title   = {A two-stage metabolome refining pipeline for natural products discovery.},    
    author  = {Zhang R, Wang B, Wang C, Huang K, Li Z, Yang J, Kuang J, Ren L, Wu M, Zhang K, Xie H, Liu Y, Wu M, Wu Y, Xu F.},    
    journal = {Synth Syst Biotechnol},    
    year    = {2025},    
    doi     = {10.1016/j.synbio.2025.01.006},    
    pmid    = {40103709}        
    }
    @article{lin343979,
    title   = {In Vitro Anti-Glioblastoma Activity of <i>Echinocereus engelmannii-</i> and <i>Echinocereus pectinatus</i>-Associated Bacterial Endophyte Extracts.},    
    author  = {Delgado-Miranda AL, Gomez-Flores R, Rodriguez-Garza NE, Perez-Gonzalez O, Tamez-Guerra P, Caballero-Hernandez D, Clark-Perez DL, Quintanilla-Licea R, Garcia A, Romo-Saenz CI.},    
    journal = {Life (Basel)},    
    year    = {2025},    
    doi     = {10.3390/life15040519},    
    pmid    = {40283074}        
    }
    @article{lin343972,
    title   = {Sequential Reconstruction of Calicheamicin gamma<sub>1</sub> <sup>I</sup> Iodo-Thiobenzoate by Selective Carrier Protein Trapping Reveals a Flavin-Dependent Iodinase.},    
    author  = {Pang F, Townsend CA.},    
    journal = {Angew Chem Int Ed Engl},    
    year    = {2025},    
    doi     = {10.1002/anie.202506825},    
    pmid    = {40540714}        
    }
    @article{lin343971,
    title   = {Evidence for Divergence of the Genus '<i>Solwaraspora</i>' Within the Bacterial Family <i>Micromonosporaceae</i>.},    
    author  = {Porter HI, Alas I, Krull NK, Braun DR, Rajski SR, Murphy BT, Bugni TS.},    
    journal = {Microorganisms},    
    year    = {2025},    
    doi     = {10.3390/microorganisms13071576},    
    pmid    = {40732085}        
    }
    @article{lin343983,
    title   = {Strategic and Chemical Advances in Antibody-Drug Conjugates.},    
    author  = {Alradwan IA, Alnefaie MK, Al Fayez N, Aodah AH, Majrashi MA, Alturki M, Fallatah MM, Almughem FA, Tawfik EA, Alshehri AA.},    
    journal = {Pharmaceutics},    
    year    = {2025},    
    doi     = {10.3390/pharmaceutics17091164},    
    pmid    = {41012501}        
    }
    @article{lin185516,
    title   = {A two-component system MechNtrB/MechNtrC related to nitrogen metabolism regulation in <i>Micromonospora echinospora</i> DSM43816.},    
    author  = {Long Y, Lu J, Leng S, Li C, Ni H, Zou L, Wu Z, Long ZE.},    
    journal = {Front Microbiol},    
    year    = {2025},    
    doi     = {10.3389/fmicb.2025.1678324},    
    pmid    = {41244688}        
    }
