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title = {The human complement regulator factor H binds pneumococcal surface protein PspC via short consensus repeats 13 to 15.},
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title = {Pneumococcal behavior and host responses during bronchopneumonia are affected differently by the cytolytic and complement-activating activities of pneumolysin.},
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title = {Contribution of a response regulator to the virulence of Streptococcus pneumoniae is strain dependent.},
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title = {CD4-T-lymphocyte interactions with pneumolysin and pneumococci suggest a crucial protective role in the host response to pneumococcal infection.},
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title = {Protection against pneumococcal pneumonia in mice by monoclonal antibodies to pneumolysin.},
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title = {Genome sequence of Avery's virulent serotype 2 strain D39 of Streptococcus pneumoniae and comparison with that of unencapsulated laboratory strain R6.},
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title = {The role of pneumolysin in mediating lung damage in a lethal pneumococcal pneumonia murine model.},
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title = {Site-specific contributions of glutamine-dependent regulator GlnR and GlnR-regulated genes to virulence of Streptococcus pneumoniae.},
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title = {Critical involvement of pneumolysin in production of interleukin-1alpha and caspase-1-dependent cytokines in infection with Streptococcus pneumoniae in vitro: a novel function of pneumolysin in caspase-1 activation.},
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title = {The efflux pump inhibitor reserpine selects multidrug-resistant Streptococcus pneumoniae strains that overexpress the ABC transporters PatA and PatB.},
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title = {Characterization of in vitro-generated and clinical optochin-resistant strains of Streptococcus pneumoniae isolated from Argentina.},
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title = {Pneumolysin released during Streptococcus pneumoniae autolysis is a potent activator of intracellular oxygen radical production in neutrophils.},
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title = {The surface-anchored NanA protein promotes pneumococcal brain endothelial cell invasion.},
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title = {Immunization with a combination of three pneumococcal proteins confers additive and broad protection against Streptococcus pneumoniae Infections in Mice.},
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title = {The pneumococcal cell envelope stress-sensing system LiaFSR is activated by murein hydrolases and lipid II-interacting antibiotics.},
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title = {Activation of brain endothelium by pneumococcal neuraminidase NanA promotes bacterial internalization.},
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title = {Human transferrin confers serum resistance against Bacillus anthracis.},
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title = {Localization and cellular amounts of the WalRKJ (VicRKX) two-component regulatory system proteins in serotype 2 Streptococcus pneumoniae.},
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@article{lin299471,
title = {Distinct cell death programs in monocytes regulate innate responses following challenge with common causes of invasive bacterial disease.},
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title = {Overexpression of patA and patB, which encode ABC transporters, is associated with fluoroquinolone resistance in clinical isolates of Streptococcus pneumoniae.},
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journal = {Antimicrob Agents Chemother},
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@article{lin299460,
title = {Impact of glutamine transporters on pneumococcal fitness under infection-related conditions.},
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@article{lin299429,
title = {Pneumolysin activates the NLRP3 inflammasome and promotes proinflammatory cytokines independently of TLR4.},
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@article{lin299432,
title = {Immunization with a ZmpB-based protein vaccine could protect against pneumococcal diseases in mice.},
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journal = {Infect Immun},
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@article{lin299445,
title = {Novel bacterial NAD+-dependent DNA ligase inhibitors with broad-spectrum activity and antibacterial efficacy in vivo.},
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title = {A cardinal role for cathepsin d in co-ordinating the host-mediated apoptosis of macrophages and killing of pneumococci.},
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title = {Proteomic evaluation and validation of cathepsin D regulated proteins in macrophages exposed to Streptococcus pneumoniae.},
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title = {A variable region within the genome of Streptococcus pneumoniae contributes to strain-strain variation in virulence.},
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title = {Role of the single-stranded DNA-binding protein SsbB in pneumococcal transformation: maintenance of a reservoir for genetic plasticity.},
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title = {Two DHH subfamily 1 proteins contribute to pneumococcal virulence and confer protection against pneumococcal disease.},
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@article{lin299403,
title = {Pneumolysin with low hemolytic activity confers an early growth advantage to Streptococcus pneumoniae in the blood.},
author = {Harvey RM, Ogunniyi AD, Chen AY, Paton JC.},
journal = {Infect Immun},
year = {2011},
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title = {Leukocyte inflammatory responses provoked by pneumococcal sialidase.},
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title = {alpha-Enolase of Streptococcus pneumoniae induces formation of neutrophil extracellular traps.},
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title = {Novel molecular method for identification of Streptococcus pneumoniae applicable to clinical microbiology and 16S rRNA sequence-based microbiome studies.},
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journal = {J Clin Microbiol},
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title = {T regulatory cells control susceptibility to invasive pneumococcal pneumonia in mice.},
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title = {Identification of genes that contribute to the pathogenesis of invasive pneumococcal disease by in vivo transcriptomic analysis.},
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journal = {Infect Immun},
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title = {The lectin pathway of complement activation is a critical component of the innate immune response to pneumococcal infection.},
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journal = {PLoS Pathog},
year = {2012},
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title = {Interplay between manganese and iron in pneumococcal pathogenesis: role of the orphan response regulator RitR.},
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journal = {Infect Immun},
year = {2013},
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title = {Parenteral fluids do not affect pulmonary immune responses to influenza or susceptibility to secondary bacterial pneumonia in mice.},
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journal = {Influenza Other Respir Viruses},
year = {2013},
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title = {Benzodiazepine augmented gamma-amino-butyric acid signaling increases mortality from pneumonia in mice.},
author = {Sanders RD, Godlee A, Fujimori T, Goulding J, Xin G, Salek-Ardakani S, Snelgrove RJ, Ma D, Maze M, Hussell T.},
journal = {Crit Care Med},
year = {2013},
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title = {Surface association of Pht proteins of Streptococcus pneumoniae.},
author = {Plumptre CD, Ogunniyi AD, Paton JC.},
journal = {Infect Immun},
year = {2013},
doi = {10.1128/iai.00562-13},
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@article{lin299358,
title = {Screening and identification of DnaJ interaction proteins in Streptococcus pneumoniae.},
author = {Cai Y, Yan W, Xu W, Yin Y, He Y, Wang H, Zhang X.},
journal = {Curr Microbiol},
year = {2013},
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@article{lin299425,
title = {A novel C5a-derived immunobiotic peptide reduces Streptococcus agalactiae colonization through targeted bacterial killing.},
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journal = {Antimicrob Agents Chemother},
year = {2013},
doi = {10.1128/aac.01590-13},
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@article{lin299378,
title = {Viability and virulence of pneumolysin, pneumococcal surface protein A, and pneumolysin/pneumococcal surface protein A mutants in the ear.},
author = {Schachern PA, Tsuprun V, Goetz S, Cureoglu S, Juhn SK, Briles DE, Paparella MM, Ferrieri P.},
journal = {JAMA Otolaryngol Head Neck Surg},
year = {2013},
doi = {10.1001/jamaoto.2013.4104},
pmid = {24051749}
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@article{lin299372,
title = {Hyaluronic acid derived from other streptococci supports Streptococcus pneumoniae in vitro biofilm formation.},
author = {Yadav MK, Chae SW, Park K, Song JJ.},
journal = {Biomed Res Int},
year = {2013},
doi = {10.1155/2013/690217},
pmid = {24171169}
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@article{lin299397,
title = {Streptococcus pneumoniae invades erythrocytes and utilizes them to evade human innate immunity.},
author = {Yamaguchi M, Terao Y, Mori-Yamaguchi Y, Domon H, Sakaue Y, Yagi T, Nishino K, Yamaguchi A, Nizet V, Kawabata S.},
journal = {PLoS One},
year = {2013},
doi = {10.1371/journal.pone.0077282},
pmid = {24194877}
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@article{lin299385,
title = {Vaccination against Streptococcus pneumoniae using truncated derivatives of polyhistidine triad protein D.},
author = {Plumptre CD, Ogunniyi AD, Paton JC.},
journal = {PLoS One},
year = {2013},
doi = {10.1371/journal.pone.0078916},
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@article{lin299383,
title = {Type I interferon signaling regulates activation of the absent in melanoma 2 inflammasome during Streptococcus pneumoniae infection.},
author = {Fang R, Hara H, Sakai S, Hernandez-Cuellar E, Mitsuyama M, Kawamura I, Tsuchiya K.},
journal = {Infect Immun},
year = {2014},
doi = {10.1128/iai.01572-14},
pmid = {24643540}
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@article{lin299351,
title = {The pneumococcal polysaccharide capsule and pneumolysin differentially affect CXCL8 and IL-6 release from cells of the upper and lower respiratory tract.},
author = {Kung E, Coward WR, Neill DR, Malak HA, Muhlemann K, Kadioglu A, Hilty M, Hathaway LJ.},
journal = {PLoS One},
year = {2014},
doi = {10.1371/journal.pone.0092355},
pmid = {24664110}
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@article{lin299402,
title = {Low-dose recombinant properdin provides substantial protection against Streptococcus pneumoniae and Neisseria meningitidis infection.},
author = {Ali YM, Hayat A, Saeed BM, Haleem KS, Alshamrani S, Kenawy HI, Ferreira VP, Saggu G, Buchberger A, Lachmann PJ, Sim RB, Goundis D, Andrew PW, Lynch NJ, Schwaeble WJ.},
journal = {Proc Natl Acad Sci U S A},
year = {2014},
doi = {10.1073/pnas.1401011111},
pmid = {24706855}
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@article{lin299390,
title = {Density and duration of pneumococcal carriage is maintained by transforming growth factor beta1 and T regulatory cells.},
author = {Neill DR, Coward WR, Gritzfeld JF, Richards L, Garcia-Garcia FJ, Dotor J, Gordon SB, Kadioglu A.},
journal = {Am J Respir Crit Care Med},
year = {2014},
doi = {10.1164/rccm.201401-0128oc},
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@article{lin299392,
title = {Development and characterization of a long-term murine model of Streptococcus pneumoniae infection of the lower airways.},
author = {Haste L, Hulland K, Bolton S, Yesilkaya H, McKechnie K, Andrew PW.},
journal = {Infect Immun},
year = {2014},
doi = {10.1128/iai.01623-14},
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@article{lin299381,
title = {Respiratory syncytial virus increases the virulence of Streptococcus pneumoniae by binding to penicillin binding protein 1a. A new paradigm in respiratory infection.},
author = {Smith CM, Sandrini S, Datta S, Freestone P, Shafeeq S, Radhakrishnan P, Williams G, Glenn SM, Kuipers OP, Hirst RA, Easton AJ, Andrew PW, O'Callaghan C.},
journal = {Am J Respir Crit Care Med},
year = {2014},
doi = {10.1164/rccm.201311-2110oc},
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@article{lin299435,
title = {Protective role of the capsule and impact of serotype 4 switching on Streptococcus mitis.},
author = {Rukke HV, Kalluru RS, Repnik U, Gerlini A, Jose RJ, Periselneris J, Marshall H, Griffiths G, Oggioni MR, Brown JS, Petersen FC.},
journal = {Infect Immun},
year = {2014},
doi = {10.1128/iai.01840-14},
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@article{lin299412,
title = {A novel protein, RafX, is important for common cell wall polysaccharide biosynthesis in Streptococcus pneumoniae: implications for bacterial virulence.},
author = {Wu K, Huang J, Zhang Y, Xu W, Xu H, Wang L, Cao J, Zhang X, Yin Y.},
journal = {J Bacteriol},
year = {2014},
doi = {10.1128/jb.01696-14},
pmid = {25002545}
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@article{lin299371,
title = {Pneumococcal PspA and PspC proteins: potential vaccine candidates for experimental otitis media.},
author = {Schachern PA, Tsuprun V, Ferrieri P, Briles DE, Goetz S, Cureoglu S, Paparella MM, Juhn S.},
journal = {Int J Pediatr Otorhinolaryngol},
year = {2014},
doi = {10.1016/j.ijporl.2014.06.024},
pmid = {25015773}
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@article{lin299373,
title = {Sinefungin, a natural nucleoside analogue of S-adenosylmethionine, inhibits Streptococcus pneumoniae biofilm growth.},
author = {Yadav MK, Park SW, Chae SW, Song JJ.},
journal = {Biomed Res Int},
year = {2014},
doi = {10.1155/2014/156987},
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@article{lin299415,
title = {An epithelial circadian clock controls pulmonary inflammation and glucocorticoid action.},
author = {Gibbs J, Ince L, Matthews L, Mei J, Bell T, Yang N, Saer B, Begley N, Poolman T, Pariollaud M, Farrow S, DeMayo F, Hussell T, Worthen GS, Ray D, Loudon A.},
journal = {Nat Med},
year = {2014},
doi = {10.1038/nm.3599},
pmid = {25064128}
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@article{lin299384,
title = {The impact of pneumolysin on the macrophage response to Streptococcus pneumoniae is strain-dependent.},
author = {Harvey RM, Hughes CE, Paton AW, Trappetti C, Tweten RK, Paton JC.},
journal = {PLoS One},
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@article{lin299386,
title = {The oral commensal Streptococcus mitis shows a mixed memory Th cell signature that is similar to and cross-reactive with Streptococcus pneumoniae.},
author = {Engen SA, Valen Rukke H, Becattini S, Jarrossay D, Blix IJ, Petersen FC, Sallusto F, Schenck K.},
journal = {PLoS One},
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@article{lin299410,
title = {Pneumolysin activates macrophage lysosomal membrane permeabilization and executes apoptosis by distinct mechanisms without membrane pore formation.},
author = {Bewley MA, Naughton M, Preston J, Mitchell A, Holmes A, Marriott HM, Read RC, Mitchell TJ, Whyte MK, Dockrell DH.},
journal = {mBio},
year = {2014},
doi = {10.1128/mbio.01710-14},
pmid = {25293758}
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@article{lin299335,
title = {Mucosal immunization with the live attenuated vaccine SPY1 induces humoral and Th2-Th17-regulatory T cell cellular immunity and protects against pneumococcal infection.},
author = {Xu X, Wang H, Liu Y, Wang Y, Zeng L, Wu K, Wang J, Ma F, Xu W, Yin Y, Zhang X.},
journal = {Infect Immun},
year = {2015},
doi = {10.1128/iai.02334-14},
pmid = {25312946}
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@article{lin299427,
title = {Conserved surface accessible nucleoside ABC transporter component SP0845 is essential for pneumococcal virulence and confers protection in vivo.},
author = {Saxena S, Khan N, Dehinwal R, Kumar A, Sehgal D.},
journal = {PLoS One},
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@article{lin299433,
title = {Co-Inactivation of GlnR and CodY Regulators Impacts Pneumococcal Cell Wall Physiology.},
author = {Johnston C, Bootsma HJ, Aldridge C, Manuse S, Gisch N, Schwudke D, Hermans PW, Grangeasse C, Polard P, Vollmer W, Claverys JP.},
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year = {2015},
doi = {10.1371/journal.pone.0123702},
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@article{lin299418,
title = {Circulating Pneumolysin Is a Potent Inducer of Cardiac Injury during Pneumococcal Infection.},
author = {Alhamdi Y, Neill DR, Abrams ST, Malak HA, Yahya R, Barrett-Jolley R, Wang G, Kadioglu A, Toh CH.},
journal = {PLoS Pathog},
year = {2015},
doi = {10.1371/journal.ppat.1004836},
pmid = {25973949}
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@article{lin299375,
title = {Exposure to welding fumes and lower airway infection with Streptococcus pneumoniae.},
author = {Suri R, Periselneris J, Lanone S, Zeidler-Erdely PC, Melton G, Palmer KT, Andujar P, Antonini JM, Cohignac V, Erdely A, Jose RJ, Mudway I, Brown J, Grigg J.},
journal = {J Allergy Clin Immunol},
year = {2016},
doi = {10.1016/j.jaci.2015.06.033},
pmid = {26277596}
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@article{lin299467,
title = {Matrikines are key regulators in modulating the amplitude of lung inflammation in acute pulmonary infection.},
author = {Akthar S, Patel DF, Beale RC, Peiro T, Xu X, Gaggar A, Jackson PL, Blalock JE, Lloyd CM, Snelgrove RJ.},
journal = {Nat Commun},
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@article{lin299389,
title = {The Small Molecule DAM Inhibitor, Pyrimidinedione, Disrupts Streptococcus pneumoniae Biofilm Growth In Vitro.},
author = {Yadav MK, Go YY, Chae SW, Song JJ.},
journal = {PLoS One},
year = {2015},
doi = {10.1371/journal.pone.0139238},
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@article{lin299388,
title = {Co-Transcriptomes of Initial Interactions In Vitro between Streptococcus Pneumoniae and Human Pleural Mesothelial Cells.},
author = {Heath CJ, del Mar Cendra M, Watson A, Auger JP, Pandey A, Tighe P, Christodoulides M.},
journal = {PLoS One},
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@article{lin299411,
title = {The Variable Region of Pneumococcal Pathogenicity Island 1 Is Responsible for Unusually High Virulence of a Serotype 1 Isolate.},
author = {Harvey RM, Trappetti C, Mahdi LK, Wang H, McAllister LJ, Scalvini A, Paton AW, Paton JC.},
journal = {Infect Immun},
year = {2016},
doi = {10.1128/iai.01454-15},
pmid = {26755156}
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@article{lin299400,
title = {Addiction of Hypertransformable Pneumococcal Isolates to Natural Transformation for In Vivo Fitness and Virulence.},
author = {Li G, Liang Z, Wang X, Yang Y, Shao Z, Li M, Ma Y, Qu F, Morrison DA, Zhang JR.},
journal = {Infect Immun},
year = {2016},
doi = {10.1128/iai.00097-16},
pmid = {27068094}
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@article{lin299387,
title = {Generation and Improvement of Effector Function of a Novel Broadly Reactive and Protective Monoclonal Antibody against Pneumococcal Surface Protein A of Streptococcus pneumoniae.},
author = {Kristian SA, Ota T, Bubeck SS, Cho R, Groff BC, Kubota T, Destito G, Martin C, Laudenslager J, Koriazova L, Tahara T, Kanda Y.},
journal = {PLoS One},
year = {2016},
doi = {10.1371/journal.pone.0154616},
pmid = {27171010}
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@article{lin299364,
title = {Duplex Quantitative PCR Assay for Detection of Haemophilus influenzae That Distinguishes Fucose- and Protein D-Negative Strains.},
author = {de Gier C, Pickering JL, Richmond PC, Thornton RB, Kirkham LA.},
journal = {J Clin Microbiol},
year = {2016},
doi = {10.1128/jcm.00982-16},
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@article{lin299404,
title = {CovR Regulates Streptococcus mutans Susceptibility To Complement Immunity and Survival in Blood.},
author = {Alves LA, Nomura R, Mariano FS, Harth-Chu EN, Stipp RN, Nakano K, Mattos-Graner RO.},
journal = {Infect Immun},
year = {2016},
doi = {10.1128/iai.00406-16},
pmid = {27572331}
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@article{lin299356,
title = {Streptococcus pneumoniae disrupts pulmonary immune defence via elastase release following pneumolysin-dependent neutrophil lysis.},
author = {Domon H, Oda M, Maekawa T, Nagai K, Takeda W, Terao Y.},
journal = {Sci Rep},
year = {2016},
doi = {10.1038/srep38013},
pmid = {27892542}
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@article{lin299370,
title = {Collectin Kidney 1 Plays an Important Role in Innate Immunity against Streptococcus pneumoniae Infection.},
author = {Hwang I, Mori K, Ohtani K, Matsuda Y, Roy N, Kim Y, Suzuki Y, Wakamiya N.},
journal = {J Innate Immun},
year = {2017},
doi = {10.1159/000453316},
pmid = {28068663}
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@article{lin299377,
title = {Autoinducer 2 Signaling via the Phosphotransferase FruA Drives Galactose Utilization by Streptococcus pneumoniae, Resulting in Hypervirulence.},
author = {Trappetti C, McAllister LJ, Chen A, Wang H, Paton AW, Oggioni MR, McDevitt CA, Paton JC.},
journal = {mBio},
year = {2017},
doi = {10.1128/mbio.02269-16},
pmid = {28119473}
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@article{lin299391,
title = {Pneumococcal infection of respiratory cells exposed to welding fumes; Role of oxidative stress and HIF-1 alpha.},
author = {Grigg J, Miyashita L, Suri R.},
journal = {PLoS One},
year = {2017},
doi = {10.1371/journal.pone.0173569},
pmid = {28278175}
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@article{lin299354,
title = {Apoptosis, Toll-like, RIG-I-like and NOD-like Receptors Are Pathways Jointly Induced by Diverse Respiratory Bacterial and Viral Pathogens.},
author = {Martinez I, Oliveros JC, Cuesta I, de la Barrera J, Ausina V, Casals C, de Lorenzo A, Garcia E, Garcia-Fojeda B, Garmendia J, Gonzalez-Nicolau M, Lacoma A, Menendez M, Moranta D, Nieto A, Ortin J, Perez-Gonzalez A, Prat C, Ramos-Sevillano E, Regueiro V, Rodriguez-Frandsen A, Solis D, Yuste J, Yuste J, Bengoechea JA, Melero JA.},
journal = {Front Microbiol},
year = {2017},
doi = {10.3389/fmicb.2017.00276},
pmid = {28298903}
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@article{lin299348,
title = {Epigallocatechin gallate inhibits Streptococcus pneumoniae virulence by simultaneously targeting pneumolysin and sortase A.},
author = {Song M, Teng Z, Li M, Niu X, Wang J, Deng X.},
journal = {J Cell Mol Med},
year = {2017},
doi = {10.1111/jcmm.13179},
pmid = {28402019}
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@article{lin299350,
title = {Impaired Mitochondrial Microbicidal Responses in Chronic Obstructive Pulmonary Disease Macrophages.},
author = {Bewley MA, Preston JA, Mohasin M, Marriott HM, Budd RC, Swales J, Collini P, Greaves DR, Craig RW, Brightling CE, Donnelly LE, Barnes PJ, Singh D, Shapiro SD, Whyte MKB, Dockrell DH.},
journal = {Am J Respir Crit Care Med},
year = {2017},
doi = {10.1164/rccm.201608-1714oc},
pmid = {28557543}
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@article{lin299421,
title = {Airway microbiota signals anabolic and catabolic remodeling in the transplanted lung.},
author = {Mouraux S, Bernasconi E, Pattaroni C, Koutsokera A, Aubert JD, Claustre J, Pison C, Royer PJ, Magnan A, Kessler R, Benden C, Soccal PM, Marsland BJ, Nicod LP, SysCLAD Consortium.},
journal = {J Allergy Clin Immunol},
year = {2018},
doi = {10.1016/j.jaci.2017.06.022},
pmid = {28729000}
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@article{lin34936,
title = {A Streptococcus pneumoniae Type 2 Oligosaccharide Glycoconjugate Elicits Opsonic Antibodies and Is Protective in an Animal Model of Invasive Pneumococcal Disease.},
author = {Emmadi M, Khan N, Lykke L, Reppe K, G Parameswarappa S, Lisboa MP, Wienhold SM, Witzenrath M, Pereira CL, Seeberger PH},
journal = {J Am Chem Soc},
year = {2017},
doi = {10.1021/jacs.7b07836},
pmid = {28945368}
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@article{lin299359,
title = {Antimicrobial and Antibiofilm Effects of Human Amniotic/Chorionic Membrane Extract on Streptococcus pneumoniae.},
author = {Yadav MK, Go YY, Kim SH, Chae SW, Song JJ.},
journal = {Front Microbiol},
year = {2017},
doi = {10.3389/fmicb.2017.01948},
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@article{lin299327,
title = {Streptococcus pneumoniae Attenuated Strain SPY1 with an Artificial Mineral Shell Induces Humoral and Th17 Cellular Immunity and Protects Mice against Pneumococcal Infection.},
author = {Zhang X, Cui J, Wu Y, Wang H, Wang J, Qiu Y, Mo Y, He Y, Zhang X, Yin Y, Xu W.},
journal = {Front Immunol},
year = {2017},
doi = {10.3389/fimmu.2017.01983},
pmid = {29375585}
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@article{lin299440,
title = {Marine Natural Peptides: Determination of Absolute Configuration Using Liquid Chromatography Methods and Evaluation of Bioactivities.},
author = {Phyo YZ, Ribeiro J, Fernandes C, Kijjoa A, Pinto MMM.},
journal = {Molecules},
year = {2018},
doi = {10.3390/molecules23020306},
pmid = {29385101}
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@article{lin299374,
title = {E-cigarette vapour enhances pneumococcal adherence to airway epithelial cells.},
author = {Miyashita L, Suri R, Dearing E, Mudway I, Dove RE, Neill DR, Van Zyl-Smit R, Kadioglu A, Grigg J.},
journal = {Eur Respir J},
year = {2018},
doi = {10.1183/13993003.01592-2017},
pmid = {29437942}
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@article{lin299422,
title = {Designer cells programming quorum-sensing interference with microbes.},
author = {Sedlmayer F, Hell D, Muller M, Auslander D, Fussenegger M.},
journal = {Nat Commun},
year = {2018},
doi = {10.1038/s41467-018-04223-7},
pmid = {29739943}
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@article{lin299342,
title = {The LuxS/AI-2 Quorum-Sensing System of Streptococcus pneumoniae Is Required to Cause Disease, and to Regulate Virulence- and Metabolism-Related Genes in a Rat Model of Middle Ear Infection.},
author = {Yadav MK, Vidal JE, Go YY, Kim SH, Chae SW, Song JJ.},
journal = {Front Cell Infect Microbiol},
year = {2018},
doi = {10.3389/fcimb.2018.00138},
pmid = {29780750}
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@article{lin299366,
title = {A novel extracellular vesicle-associated endodeoxyribonuclease helps Streptococcus pneumoniae evade neutrophil extracellular traps and is required for full virulence.},
author = {Jhelum H, Sori H, Sehgal D.},
journal = {Sci Rep},
year = {2018},
doi = {10.1038/s41598-018-25865-z},
pmid = {29789571}
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@article{lin299361,
title = {Neutrophil Elastase Subverts the Immune Response by Cleaving Toll-Like Receptors and Cytokines in Pneumococcal Pneumonia.},
author = {Domon H, Nagai K, Maekawa T, Oda M, Yonezawa D, Takeda W, Hiyoshi T, Tamura H, Yamaguchi M, Kawabata S, Terao Y.},
journal = {Front Immunol},
year = {2018},
doi = {10.3389/fimmu.2018.00732},
pmid = {29922273}
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title = {Deep genome annotation of the opportunistic human pathogen Streptococcus pneumoniae D39.},
author = {Slager J, Aprianto R, Veening JW.},
journal = {Nucleic Acids Res},
year = {2018},
doi = {10.1093/nar/gky725},
pmid = {30107613}
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@article{lin299376,
title = {Protective Regulatory T Cell Immune Response Induced by Intranasal Immunization With the Live-Attenuated Pneumococcal Vaccine SPY1 via the Transforming Growth Factor-beta1-Smad2/3 Pathway.},
author = {Liao H, Peng X, Gan L, Feng J, Gao Y, Yang S, Hu X, Zhang L, Yin Y, Wang H, Xu X.},
journal = {Front Immunol},
year = {2018},
doi = {10.3389/fimmu.2018.01754},
pmid = {30116243}
}
@article{lin299338,
title = {Mechanism of Macrolide-Induced Inhibition of Pneumolysin Release Involves Impairment of Autolysin Release in Macrolide-Resistant Streptococcus pneumoniae.},
author = {Domon H, Maekawa T, Yonezawa D, Nagai K, Oda M, Yanagihara K, Terao Y.},
journal = {Antimicrob Agents Chemother},
year = {2018},
doi = {10.1128/aac.00161-18},
pmid = {30181369}
}
@article{lin299341,
title = {The Pneumococcal Surface Proteins PspA and PspC Sequester Host C4-Binding Protein To Inactivate Complement C4b on the Bacterial Surface.},
author = {Haleem KS, Ali YM, Yesilkaya H, Kohler T, Hammerschmidt S, Andrew PW, Schwaeble WJ, Lynch NJ.},
journal = {Infect Immun},
year = {2019},
doi = {10.1128/iai.00742-18},
pmid = {30323030}
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@article{lin299379,
title = {Pneumolysin binds to the mannose receptor C type 1 (MRC-1) leading to anti-inflammatory responses and enhanced pneumococcal survival.},
author = {Subramanian K, Neill DR, Malak HA, Spelmink L, Khandaker S, Dalla Libera Marchiori G, Dearing E, Kirby A, Yang M, Achour A, Nilvebrant J, Nygren PA, Plant L, Kadioglu A, Henriques-Normark B.},
journal = {Nat Microbiol},
year = {2019},
doi = {10.1038/s41564-018-0280-x},
pmid = {30420782}
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@article{lin299343,
title = {TLR4 deficiency reduces pulmonary resistance to Streptococcus pneumoniae in gut microbiota-disrupted mice.},
author = {Wang H, Lian P, Niu X, Zhao L, Mu X, Feng B, Li J, Liang Z, Qiao J.},
journal = {PLoS One},
year = {2018},
doi = {10.1371/journal.pone.0209183},
pmid = {30562386}
}
@article{lin299365,
title = {PCV7- and PCV10-Vaccinated Otitis-Prone Children in New Zealand Have Similar Pneumococcal and Haemophilus influenzae Densities in Their Nasopharynx and Middle Ear.},
author = {de Gier C, Granland CM, Pickering JL, Walls T, Bhuiyan M, Mills N, Richmond PC, Best EJ, Thornton RB, Kirkham LS.},
journal = {Vaccines (Basel)},
year = {2019},
doi = {10.3390/vaccines7010014},
pmid = {30708945}
}
@article{lin299355,
title = {Redefining the Small Regulatory RNA Transcriptome in Streptococcus pneumoniae Serotype 2 Strain D39.},
author = {Sinha D, Zimmer K, Cameron TA, Rusch DB, Winkler ME, De Lay NR.},
journal = {J Bacteriol},
year = {2019},
doi = {10.1128/jb.00764-18},
pmid = {30833353}
}
@article{lin299396,
title = {Conformational and dynamic plasticity in substrate-binding proteins underlies selective transport in ABC importers.},
author = {de Boer M, Gouridis G, Vietrov R, Begg SL, Schuurman-Wolters GK, Husada F, Eleftheriadis N, Poolman B, McDevitt CA, Cordes T.},
journal = {Elife},
year = {2019},
doi = {10.7554/elife.44652},
pmid = {30900991}
}
@article{lin299333,
title = {Mitochondrial DNA Leakage Caused by Streptococcus pneumoniae Hydrogen Peroxide Promotes Type I IFN Expression in Lung Cells.},
author = {Gao Y, Xu W, Dou X, Wang H, Zhang X, Yang S, Liao H, Hu X, Wang H.},
journal = {Front Microbiol},
year = {2019},
doi = {10.3389/fmicb.2019.00630},
pmid = {30984149}
}
@article{lin299395,
title = {Photocatalytic Protein Damage by Silver Nanoparticles Circumvents Bacterial Stress Response and Multidrug Resistance.},
author = {Shi T, Wei Q, Wang Z, Zhang G, Sun X, He QY.},
journal = {mSphere},
year = {2019},
doi = {10.1128/msphere.00175-19},
pmid = {31043515}
}
@article{lin299346,
title = {Streptococcus pneumoniae inhibits purinergic signaling and promotes purinergic receptor P2Y2 internalization in alveolar epithelial cells.},
author = {Olotu C, Lehmensiek F, Koch B, Kiefmann M, Riegel AK, Hammerschmidt S, Kiefmann R.},
journal = {J Biol Chem},
year = {2019},
doi = {10.1074/jbc.ra118.007236},
pmid = {31289122}
}
@article{lin299362,
title = {Role of Pneumococcal NanA Neuraminidase Activity in Peripheral Blood.},
author = {Syed S, Hakala P, Singh AK, Lapatto HAK, King SJ, Meri S, Jokiranta TS, Haapasalo K.},
journal = {Front Cell Infect Microbiol},
year = {2019},
doi = {10.3389/fcimb.2019.00218},
pmid = {31297339}
}
@article{lin299407,
title = {Extreme Environment Streptomyces: Potential Sources for New Antibacterial and Anticancer Drug Leads?},
author = {Sivalingam P, Hong K, Pote J, Prabakar K, Prabakar K.},
journal = {Int J Microbiol},
year = {2019},
doi = {10.1155/2019/5283948},
pmid = {31354829}
}
@article{lin299368,
title = {In vivo proteomics identifies the competence regulon and AliB oligopeptide transporter as pathogenic factors in pneumococcal meningitis.},
author = {Schmidt F, Kakar N, Meyer TC, Depke M, Masouris I, Burchhardt G, Gomez-Mejia A, Dhople V, Havarstein LS, Sun Z, Moritz RL, Volker U, Koedel U, Hammerschmidt S.},
journal = {PLoS Pathog},
year = {2019},
doi = {10.1371/journal.ppat.1007987},
pmid = {31356624}
}
@article{lin299347,
title = {The Tyrosine-Autokinase UbK Is Required for Proper Cell Growth and Cell Morphology of Streptococcus pneumoniae.},
author = {Pelletier A, Freton C, Gallay C, Trouve J, Cluzel C, Franz-Wachtel M, Macek B, Jault JM, Grangeasse C, Guiral S.},
journal = {Front Microbiol},
year = {2019},
doi = {10.3389/fmicb.2019.01942},
pmid = {31551943}
}
@article{lin299357,
title = {Peptidoglycan Recognition Protein 4 Limits Bacterial Clearance and Inflammation in Lungs by Control of the Gut Microbiota.},
author = {Dabrowski AN, Shrivastav A, Conrad C, Komma K, Weigel M, Dietert K, Gruber AD, Bertrams W, Wilhelm J, Schmeck B, Reppe K, N'Guessan PD, Aly S, Suttorp N, Hain T, Zahlten J.},
journal = {Front Immunol},
year = {2019},
doi = {10.3389/fimmu.2019.02106},
pmid = {31616404}
}
@article{lin299367,
title = {The clock gene Bmal1 inhibits macrophage motility, phagocytosis, and impairs defense against pneumonia.},
author = {Kitchen GB, Cunningham PS, Poolman TM, Iqbal M, Maidstone R, Baxter M, Bagnall J, Begley N, Saer B, Hussell T, Matthews LC, Dockrell DH, Durrington HJ, Gibbs JE, Blaikley JF, Loudon AS, Ray DW.},
journal = {Proc Natl Acad Sci U S A},
year = {2020},
doi = {10.1073/pnas.1915932117},
pmid = {31900362}
}
@article{lin299360,
title = {Exposure to diesel exhaust particles increases susceptibility to invasive pneumococcal disease.},
author = {Shears RK, Jacques LC, Naylor G, Miyashita L, Khandaker S, Lebre F, Lavelle EC, Grigg J, French N, Neill DR, Kadioglu A.},
journal = {J Allergy Clin Immunol},
year = {2020},
doi = {10.1016/j.jaci.2019.11.039},
pmid = {31983527}
}
@article{lin34925,
title = {The roles of genes associated with regulation, transportation, and macrocyclization in desotamide biosynthesis in Streptomyces scopuliridis SCSIO ZJ46.},
author = {Ding W, Dong Y, Ju J, Li Q},
journal = {Appl Microbiol Biotechnol},
year = {2020},
doi = {10.1007/s00253-020-10414-4},
pmid = {32002605}
}
@article{lin299325,
title = {Streptococcus pneumoniae PepO promotes host anti-infection defense via autophagy in a Toll-like receptor 2/4 dependent manner.},
author = {Shu Z, Yuan J, Wang H, Zhang J, Li S, Zhang H, Liu Y, Yin Y, Zhang X.},
journal = {Virulence},
year = {2020},
doi = {10.1080/21505594.2020.1739411},
pmid = {32172666}
}
@article{lin299331,
title = {Proteomic Adaptation of Streptococcus pneumoniae to the Human Antimicrobial Peptide LL-37.},
author = {Mucke PA, Maass S, Kohler TP, Hammerschmidt S, Becher D.},
journal = {Microorganisms},
year = {2020},
doi = {10.3390/microorganisms8030413},
pmid = {32183275}
}
@article{lin299319,
title = {Antimicrobial, Cytotoxic, and Antioxidant Potential of a Novel Flavone "6,7,4'-Trimethyl Flavone" Isolated from Wulfenia amherstiana.},
author = {Kakar M, Kakar M, Amin MU, Alghamdi S, Sahibzada MUK, Ahmad N, Ullah N.},
journal = {Evid Based Complement Alternat Med},
year = {2020},
doi = {10.1155/2020/3903682},
pmid = {32190082}
}
@article{lin299324,
title = {Urban Particles Elevated Streptococcus pneumoniae Biofilms, Colonization of the Human Middle Ear Epithelial Cells, Mouse Nasopharynx and Transit to the Middle Ear and Lungs.},
author = {Yadav MK, Go YY, Jun I, Chae SW, Song JJ.},
journal = {Sci Rep},
year = {2020},
doi = {10.1038/s41598-020-62846-7},
pmid = {32249803}
}
@article{lin299330,
title = {The B-cell inhibitory receptor CD22 is a major factor in host resistance to Streptococcus pneumoniae infection.},
author = {Fernandes VE, Ercoli G, Benard A, Brandl C, Fahnenstiel H, Muller-Winkler J, Weber GF, Denny P, Nitschke L, Andrew PW.},
journal = {PLoS Pathog},
year = {2020},
doi = {10.1371/journal.ppat.1008464},
pmid = {32324805}
}
@article{lin299337,
title = {Disruption of the cpsE and endA Genes Attenuates Streptococcus pneumoniae Virulence: Towards the Development of a Live Attenuated Vaccine Candidate.},
author = {Amonov M, Simbak N, Wan Hassan WMR, Ismail S, A Rahman NI, Clarke SC, Yeo CC.},
journal = {Vaccines (Basel)},
year = {2020},
doi = {10.3390/vaccines8020187},
pmid = {32326482}
}
@article{lin299406,
title = {HIF-1alpha is involved in blood-brain barrier dysfunction and paracellular migration of bacteria in pneumococcal meningitis.},
author = {Devraj G, Guerit S, Seele J, Spitzer D, Macas J, Khel MI, Heidemann R, Braczynski AK, Ballhorn W, Gunther S, Ogunshola OO, Mittelbronn M, Kodel U, Monoranu CM, Plate KH, Hammerschmidt S, Nau R, Devraj K, Kempf VAJ.},
journal = {Acta Neuropathol},
year = {2020},
doi = {10.1007/s00401-020-02174-2},
pmid = {32529267}
}
@article{lin299318,
title = {Cortex Cercis chinensis Granules Attenuate Streptococcus pneumoniae Virulence by Targeting Pneumolysin.},
author = {Xu Y, Wang Y, Guo Y, Wei L, Ding L, Wang Z, Sun L.},
journal = {Evid Based Complement Alternat Med},
year = {2020},
doi = {10.1155/2020/8537026},
pmid = {32617112}
}
@article{lin299322,
title = {Site-Specific Mutations of GalR Affect Galactose Metabolism in Streptococcus pneumoniae.},
author = {McLean KT, Tikhomirova A, Brazel EB, Legendre S, Haasbroek G, Minhas V, Paton JC, Trappetti C.},
journal = {J Bacteriol},
year = {2020},
doi = {10.1128/jb.00180-20},
pmid = {33046563}
}
@article{lin299323,
title = {Targeting Streptococcus pneumoniae UDP-glucose pyrophosphorylase (UGPase): in vitro validation of a putative inhibitor.},
author = {Sharma M, Sharma S, Ray P, Chakraborti A.},
journal = {Drug Target Insights},
year = {2020},
doi = {10.33393/dti.2020.2103},
pmid = {33132696}
}
@article{lin299313,
title = {Proteomic Adaptation of Streptococcus pneumoniae to the Antimicrobial Peptide Human Beta Defensin 3 (hBD3) in Comparison to Other Cell Surface Stresses.},
author = {Mucke PA, Ostrzinski A, Hammerschmidt S, Maass S, Becher D.},
journal = {Microorganisms},
year = {2020},
doi = {10.3390/microorganisms8111697},
pmid = {33143252}
}
@article{lin299353,
title = {Lower Density and Shorter Duration of Nasopharyngeal Carriage by Pneumococcal Serotype 1 (ST217) May Explain Its Increased Invasiveness over Other Serotypes.},
author = {Bricio-Moreno L, Chaguza C, Yahya R, Shears RK, Cornick JE, Hokamp K, Yang M, Neill DR, French N, Hinton JCD, Everett DB, Kadioglu A.},
journal = {mBio},
year = {2020},
doi = {10.1128/mbio.00814-20},
pmid = {33293378}
}
@article{lin299328,
title = {Evidence of TCM Theory in Treating the Same Disease with Different Methods: Treatment of Pneumonia with Ephedra sinica and Scutellariae Radix as an Example.},
author = {Sun L, Wang D, Xu Y, Qi W, Wang Y.},
journal = {Evid Based Complement Alternat Med},
year = {2020},
doi = {10.1155/2020/8873371},
pmid = {33354223}
}
@article{lin299339,
title = {Pneumococcal Colonization and Virulence Factors Identified Via Experimental Evolution in Infection Models.},
author = {Green AE, Howarth D, Chaguza C, Echlin H, Langendonk RF, Munro C, Barton TE, Hinton JCD, Bentley SD, Rosch JW, Neill DR.},
journal = {Mol Biol Evol},
year = {2021},
doi = {10.1093/molbev/msab018},
pmid = {33502519}
}
@article{lin299329,
title = {A Triple-challenge Mouse Model of Allergic Airway Disease, Primary Influenza Infection, and Secondary Bacterial Infection.},
author = {Roberts S, Williams CM, Roy S, Furuya Y.},
journal = {Bio Protoc},
year = {2020},
doi = {10.21769/bioprotoc.3583},
pmid = {33659553}
}
@article{lin299311,
title = {Increased Pulmonary Pneumococcal Clearance after Resolution of H9N2 Avian Influenza Virus Infection in Mice.},
author = {Li J, Wang H, Lian P, Bai Y, Zhang Z, Zhao L, Xu T, Qiao J.},
journal = {Infect Immun},
year = {2021},
doi = {10.1128/iai.00062-21},
pmid = {33722928}
}
@article{lin299316,
title = {Intestinal helminth co-infection is an unrecognised risk factor for increased pneumococcal carriage density and invasive disease.},
author = {Law AE, Shears RK, Lopez Rodas AA, Grencis RK, Cooper PJ, Neill DR, Kadioglu A.},
journal = {Sci Rep},
year = {2021},
doi = {10.1038/s41598-021-86508-4},
pmid = {33772094}
}
@article{lin299340,
title = {Synthetic Analogs of Streptococcus pneumoniae Capsular Polysaccharides and Immunogenic Activities of Glycoconjugates.},
author = {Gening ML, Kurbatova EA, Nifantiev NE.},
journal = {Russ J Bioorg Chem},
year = {2021},
doi = {10.1134/s1068162021010076},
pmid = {33776393}
}
@article{lin299345,
title = {Novel Virulence Role of Pneumococcal NanA in Host Inflammation and Cell Death Through the Activation of Inflammasome and the Caspase Pathway.},
author = {Tseng YW, Chang CC, Chang YC.},
journal = {Front Cell Infect Microbiol},
year = {2021},
doi = {10.3389/fcimb.2021.613195},
pmid = {33777832}
}
@article{lin299382,
title = {A prevalent and culturable microbiota links ecological balance to clinical stability of the human lung after transplantation.},
author = {Das S, Bernasconi E, Koutsokera A, Wurlod DA, Tripathi V, Bonilla-Rosso G, Aubert JD, Derkenne MF, Mercier L, Pattaroni C, Rapin A, von Garnier C, Marsland BJ, Engel P, Nicod LP.},
journal = {Nat Commun},
year = {2021},
doi = {10.1038/s41467-021-22344-4},
pmid = {33837203}
}
@article{lin299332,
title = {Characterization of the Anti-Inflammatory Capacity of IL-10-Producing Neutrophils in Response to Streptococcus pneumoniae Infection.},
author = {Gonzalez LA, Melo-Gonzalez F, Sebastian VP, Vallejos OP, Noguera LP, Suazo ID, Schultz BM, Manosalva AH, Penaloza HF, Soto JA, Parker D, Riedel CA, Gonzalez PA, Kalergis AM, Bueno SM.},
journal = {Front Immunol},
year = {2021},
doi = {10.3389/fimmu.2021.638917},
pmid = {33995357}
}
@article{lin299380,
title = {Antimicrobial Activity of Human Fetal Membranes: From Biological Function to Clinical Use.},
author = {Ramuta TZ, Sket T, Starcic Erjavec M, Kreft ME.},
journal = {Front Bioeng Biotechnol},
year = {2021},
doi = {10.3389/fbioe.2021.691522},
pmid = {34136474}
}
@article{lin299336,
title = {The MpsAB Bicarbonate Transporter Is Superior to Carbonic Anhydrase in Biofilm-Forming Bacteria with Limited CO2 Diffusion.},
author = {Fan SH, Matsuo M, Huang L, Tribelli PM, Gotz F.},
journal = {Microbiol Spectr},
year = {2021},
doi = {10.1128/spectrum.00305-21},
pmid = {34287032}
}
@article{lin299369,
title = {CcrZ is a pneumococcal spatiotemporal cell cycle regulator that interacts with FtsZ and controls DNA replication by modulating the activity of DnaA.},
author = {Gallay C, Sanselicio S, Anderson ME, Soh YM, Liu X, Stamsas GA, Pelliciari S, van Raaphorst R, Denereaz J, Kjos M, Murray H, Gruber S, Grossman AD, Veening JW.},
journal = {Nat Microbiol},
year = {2021},
doi = {10.1038/s41564-021-00949-1},
pmid = {34373624}
}
@article{lin299320,
title = {Resistance of Streptococcus pneumoniae to Hypothiocyanous Acid Generated by Host Peroxidases.},
author = {Shearer HL, Kaldor CD, Hua H, Kettle AJ, Parker HA, Hampton MB.},
journal = {Infect Immun},
year = {2022},
doi = {10.1128/iai.00530-21},
pmid = {35156851}
}
@article{lin299315,
title = {Comparative Metabolic Pathways Analysis and Subtractive Genomics Profiling to Prioritize Potential Drug Targets Against Streptococcus pneumoniae.},
author = {Khan K, Jalal K, Khan A, Al-Harrasi A, Uddin R.},
journal = {Front Microbiol},
year = {2021},
doi = {10.3389/fmicb.2021.796363},
pmid = {35222301}
}
@article{lin299300,
title = {Antimicrobial Susceptibility Pattern and Serotype Distribution of Streptococcus pneumoniae Isolates From a Hospital-Based Study in Chandigarh, North India.},
author = {Sharma S, Sharma M, Ray P, Chakraborti A.},
journal = {Cureus},
year = {2022},
doi = {10.7759/cureus.21437},
pmid = {35223224}
}
@article{lin299321,
title = {Underground railway particulate matter and susceptibility to pneumococcal infection.},
author = {Miyashita L, Shears R, Foley G, Semple S, Kadioglu A, Grigg J.},
journal = {EBioMedicine},
year = {2022},
doi = {10.1016/j.ebiom.2022.104063},
pmid = {35598440}
}
@article{lin299352,
title = {Synthetic Glycans to Improve Current Glycoconjugate Vaccines and Fight Antimicrobial Resistance.},
author = {Del Bino L, Osterlid KE, Wu DY, Nonne F, Romano MR, Codee J, Adamo R.},
journal = {Chem Rev},
year = {2022},
doi = {10.1021/acs.chemrev.2c00021},
pmid = {35608633}
}
@article{lin299363,
title = {Host protease activity classifies pneumonia etiology.},
author = {Anahtar M, Chan LW, Ko H, Rao A, Soleimany AP, Khatri P, Bhatia SN.},
journal = {Proc Natl Acad Sci U S A},
year = {2022},
doi = {10.1073/pnas.2121778119},
pmid = {35696579}
}
@article{lin299317,
title = {Procoagulant Activity of Blood and Microvesicles Is Disturbed by Pneumococcal Pneumolysin, Which Interacts with Coagulation Factors.},
author = {Oehmcke-Hecht S, Maletzki C, Surabhi S, Siemens N, Khaimov V, John LM, Peter SM, Hammerschmidt S, Kreikemeyer B.},
journal = {J Innate Immun},
year = {2023},
doi = {10.1159/000525479},
pmid = {35843205}
}
@article{lin299314,
title = {Mycoplasma pneumoniae Compared to Streptococcus pneumoniae Avoids Induction of Proinflammatory Epithelial Cell Responses despite Robustly Inducing TLR2 Signaling.},
author = {de Groot RCA, Zhu H, Hoogenboezem T, de Bruijn ACJM, Eenjes E, 't Jong AEJ, Belo AI, Estevao SC, Bajramovic JJ, Rottier RJ, Kool M, van Rossum AMC, Unger WWJ.},
journal = {Infect Immun},
year = {2022},
doi = {10.1128/iai.00129-22},
pmid = {35862703}
}
@article{lin299304,
title = {Streptococcus pneumoniae Rapidly Translocate from the Nasopharynx through the Cribriform Plate to Invade the Outer Meninges.},
author = {Audshasai T, Coles JA, Panagiotou S, Khandaker S, Scales HE, Kjos M, Baltazar M, Vignau J, Brewer JM, Kadioglu A, Yang M.},
journal = {mBio},
year = {2022},
doi = {10.1128/mbio.01024-22},
pmid = {35924840}
}
@article{lin299307,
title = {A newly identified flavoprotein disulfide reductase Har protects Streptococcus pneumoniae against hypothiocyanous acid.},
author = {Shearer HL, Pace PE, Paton JC, Hampton MB, Dickerhof N.},
journal = {J Biol Chem},
year = {2022},
doi = {10.1016/j.jbc.2022.102359},
pmid = {35952759}
}
@article{lin299301,
title = {Corilagin: A Novel Antivirulence Strategy to Alleviate Streptococcus pneumoniae Infection by Diminishing Pneumolysin Oligomers.},
author = {Sheng Q, Hou X, Wang N, Liu M, Zhu H, Deng X, Liang X, Chi G.},
journal = {Molecules},
year = {2022},
doi = {10.3390/molecules27165063},
pmid = {36014299}
}
@article{lin299293,
title = {Therapeutic potential of kaempferol on Streptococcus pneumoniae infection.},
author = {Xu L, Fang J, Ou D, Xu J, Deng X, Chi G, Feng H, Wang J.},
journal = {Microbes Infect},
year = {2023},
doi = {10.1016/j.micinf.2022.105058},
pmid = {36216303}
}
@article{lin299309,
title = {A Mouse Model for the Transition of Streptococcus pneumoniae from Colonizer to Pathogen upon Viral Co-Infection Recapitulates Age-Exacerbated Illness.},
author = {Lenhard A, Joma BH, Siwapornchai N, Hakansson AP, Leong JM, Bou Ghanem EN.},
journal = {J Vis Exp},
year = {2022},
doi = {10.3791/64419},
pmid = {36279528}
}
@article{lin299305,
title = {Antimicrobial Activity of Peptide-Coupled Antisense Peptide Nucleic Acids in Streptococcus pneumoniae.},
author = {Barkowsky G, Abt C, Pohner I, Bieda A, Hammerschmidt S, Jacob A, Kreikemeyer B, Patenge N.},
journal = {Microbiol Spectr},
year = {2022},
doi = {10.1128/spectrum.00497-22},
pmid = {36321914}
}
@article{lin299310,
title = {Antibiotic Tolerance Indicative of Persistence Is Pervasive among Clinical Streptococcus pneumoniae Isolates and Shows Strong Condition Dependence.},
author = {Geerts N, De Vooght L, Passaris I, Delputte P, Van den Bergh B, Cos P.},
journal = {Microbiol Spectr},
year = {2022},
doi = {10.1128/spectrum.02701-22},
pmid = {36374111}
}
@article{lin299326,
title = {Pharmacological and analytical aspects of alkannin/shikonin and their derivatives: An update from 2008 to 2022.},
author = {Kaur K, Sharma R, Singh A, Attri S, Arora S, Kaur S, Bedi N.},
journal = {Chin Herb Med},
year = {2022},
doi = {10.1016/j.chmed.2022.08.001},
pmid = {36405061}
}
@article{lin299299,
title = {Wogonin attenuates the pathogenicity of Streptococcus pneumoniae by double-target inhibition of Pneumolysin and Sortase A.},
author = {Gu K, Ding L, Wang Z, Sun Y, Sun X, Yang W, Sun H, Tian Y, Wang Z, Sun L.},
journal = {J Cell Mol Med},
year = {2023},
doi = {10.1111/jcmm.17684},
pmid = {36747468}
}
@article{lin299306,
title = {The association between serum complement C3a and severity in patients with community-acquired pneumonia.},
author = {Xu Z, Hou XF, Feng CM, Zheng L, Xu DX, Zhao H, Fu L.},
journal = {Front Immunol},
year = {2023},
doi = {10.3389/fimmu.2023.1034233},
pmid = {36776834}
}
@article{lin299334,
title = {Caspase-8 inhibition improves the outcome of bacterial infections in mice by promoting neutrophil activation.},
author = {Lentini G, Fama A, De Gaetano GV, Coppolino F, Mahjoub AK, Ryan L, Lien E, Espevik T, Beninati C, Teti G.},
journal = {Cell Rep Med},
year = {2023},
doi = {10.1016/j.xcrm.2023.101098},
pmid = {37390829}
}
@article{lin299303,
title = {IL-27 mediates immune response of pneumococcal vaccine SPY1 through Th17 and memory CD4+T cells.},
author = {Zhang Y, Gao S, Yao S, Weng D, Wang Y, Huang Q, Zhang X, Wang H, Xu W.},
journal = {iScience},
year = {2023},
doi = {10.1016/j.isci.2023.107464},
pmid = {37588169}
}
@article{lin299292,
title = {In vitro antibacterial activity of dinuclear thiolato-bridged ruthenium(II)-arene compounds.},
author = {Bugnon Q, Melendez C, Desiatkina O, Fayolles de Chaptes L, Holzer I, Paunescu E, Hilty M, Furrer J.},
journal = {Microbiol Spectr},
year = {2023},
doi = {10.1128/spectrum.00954-23},
pmid = {37815336}
}
@article{lin299308,
title = {hsdSA regulated extracellular vesicle-associated PLY to protect Streptococcus pneumoniae from macrophage killing via LAPosomes.},
author = {Wang L, Liu M, Qi Y, Wang J, Shi Q, Xie X, Zhou C, Ma L.},
journal = {Microbiol Spectr},
year = {2024},
doi = {10.1128/spectrum.00995-23},
pmid = {38018988}
}
@article{lin299296,
title = {Combining antibiotic with anti-TLR2/TLR13 therapy prevents brain pathology in pneumococcal meningitis.},
author = {Dyckhoff-Shen S, Masouris I, Islam H, Hammerschmidt S, Angele B, Marathe V, Buer J, Volk S, Pfister HW, Klein M, Koedel U, Kirschning CJ.},
journal = {JCI Insight},
year = {2024},
doi = {10.1172/jci.insight.165737},
pmid = {38358825}
}
@article{lin299294,
title = {Enhancing explainable SARS-CoV-2 vaccine development leveraging bee colony optimised Bi-LSTM, Bi-GRU models and bioinformatic analysis.},
author = {Ozsahin DU, Ameen ZS, Hassan AS, Mubarak AS.},
journal = {Sci Rep},
year = {2024},
doi = {10.1038/s41598-024-55762-7},
pmid = {38509174}
}
@article{lin299302,
title = {AMP-Coated TiO2 Doped ZnO Nanomaterials Enhanced Antimicrobial Activity and Efficacy in Otitis Media Treatment by Elevating Hydroxyl Radical Levels.},
author = {Bai Q, Zhang Y, Cai R, Wu H, Fu H, Zhou X, Chai J, Teng X, Liu T.},
journal = {Int J Nanomedicine},
year = {2024},
doi = {10.2147/ijn.s449888},
pmid = {38559446}
}
@article{lin299297,
title = {Hydrogen peroxide is responsible for the cytotoxic effects of Streptococcus pneumoniae on primary microglia in the absence of pneumolysin.},
author = {Jennert F, Schaaf D, Nau R, Kohler TP, Hammerschmidt S, Hausler D, Valentin-Weigand P, Seele J.},
journal = {J Innate Immun},
year = {2024},
doi = {10.1159/000536514},
pmid = {38569474}
}
@article{lin299298,
title = {GpsB Coordinates StkP Signaling as a PASTA Kinase Adaptor in Streptococcus pneumoniae Cell Division.},
author = {Stauberova V, Kubesa B, Joseph M, Benedet M, Furlan B, Buriankova K, Ulrych A, Kupcik R, Vomastek T, Massidda O, Tsui HT, Winkler ME, Branny P, Doubravova L.},
journal = {J Mol Biol},
year = {2024},
doi = {10.1016/j.jmb.2024.168797},
pmid = {39303764}
}
@article{lin299291,
title = {PneumoBrowse 2: an integrated visual platform for curated genome annotation and multiomics data analysis of Streptococcus pneumoniae.},
author = {Janssen AB, Gibson PS, Bravo AM, de Bakker V, Slager J, Veening JW.},
journal = {Nucleic Acids Res},
year = {2025},
doi = {10.1093/nar/gkae923},
pmid = {39436044}
}
@article{lin299290,
title = {Early detection of bacterial pneumonia by characteristic induced odor signatures.},
author = {Arnold K, Gomez-Mejia A, de Figueiredo M, Boccard J, Singh KD, Rudaz S, Sinues P, Zinkernagel AS.},
journal = {BMC Infect Dis},
year = {2024},
doi = {10.1186/s12879-024-10371-7},
pmid = {39731069}
}
@article{lin299344,
title = {Research Progress on the Antibacterial Activity of Natural Flavonoids.},
author = {Zhang Z, Cao M, Shang Z, Xu J, Chen X, Zhu Z, Wang W, Wei X, Zhou X, Bai Y, Zhang J.},
journal = {Antibiotics (Basel)},
year = {2025},
doi = {10.3390/antibiotics14040334},
pmid = {40298463}
}
@article{lin299289,
title = {Antibiotic resistance and factors associated with colonization dynamics of Staphylococcus aureus and Streptococcus pneumoniae in healthy children in Lima, Peru.},
author = {Li Valverde VM, Aguirre Castaneda PC, Gonzales BE, Castillo-Tokumori F, Vidal JE, Ochoa TJ.},
journal = {Epidemiol Infect},
year = {2025},
doi = {10.1017/s0950268825100277},
pmid = {40903821}
}
@article{lin299295,
title = {New Streptomyces-Derived Antibacterial Compounds Targeting Gram-Positive Bacteria: A Systematic Review.},
author = {Ait Assou S, El Hassouni M.},
journal = {ScientificWorldJournal},
year = {2025},
doi = {10.1155/tswj/6659874},
pmid = {41040133}
}
@article{lin299288,
title = {Montelukast treats Streptococcus pneumoniae-induced sepsis via antibacterial and anti-inflammatory activities.},
author = {Cao W, Xu D, Yu H, Shen X.},
journal = {Microbiol Spectr},
year = {2025},
doi = {10.1128/spectrum.01221-25},
pmid = {41090944}
}