Metamycoplasma orale (DSM 25590, ATCC 23714, CIP 104969)

Name: Metamycoplasma orale (DSM 25590, ATCC 23714, CIP 104969)
Creator: BacDive
License: http://creativecommons.org/licenses/by/4.0/

BacDive ID 8613

Type strain

Strain Designation CH19299, CH 19299

Culture col. no. DSM 25590 ATCC 23714 CIP 104969 IFO (now NBRC) 14477 NCTC 10112 2 more

NCBI tax ID(s) 1266996 2121

Special Collections DSMZ CIP

Links

Metamycoplasma orale CH19299 is a mesophilic, Gram-negative, rod-shaped prokaryote that was isolated from Oropharynx of child.

Gram-negative rod-shaped mesophilic genome sequence 16S sequence

Name and taxonomic classification

SI-ID 38198

ATCC 23714,NCTC 10112,CIP 104969,IFO 14477,NBRC 14477,DSM 25590

@ref 20215

Last LPSN update 2025-12-16 09:48:53

Domain Bacillati

Phylum Mycoplasmatota

Class Mollicutes

Order Mycoplasmoidales

Family Metamycoplasmataceae

Genus Metamycoplasma

Species Metamycoplasma orale

Full scientific name Metamycoplasma orale (Taylor-Robinson et al. 1964) Gupta et al. 2018

Synonyms (1)

Mycoplasma orale

BacDive ID	Other strains from **Metamycoplasma orale** (2)	Type strain
8612	M. orale ZK-CU3, DSM 19105
175214	M. orale MT-4, DSM 116279

Morphology

Cell morphology

@ref	Gram stain	Cell shape	Confidence
121427	negative	rod-shaped
125439	negative		99.7
125438			94.93

Colony morphology

18055

Incubation period1-2 days

Culture and growth conditions

Culture medium

@ref	Name	Medium link	Composition
18055	SP4-Z MEDIUM (DSMZ Medium 1076b)	Medium recipe at MediaDive	Name: SP4-Z MEDIUM (DSMZ Medium 1076b) Composition: Agar 10.0 g/l Tryptone 10.0 g/l Bacto peptone 5.0 g/l PPLO broth 3.5 g/l Urea 2.0 g/l Glucose 1.0 g/l None 1.0 g/l Yeast extract 0.4 g/l DNA 0.2 g/l CMRL 1066 Fetal bovine serum Swine serum Distilled water
121427	CIP Medium 749	Medium recipe at CIP
121427	CIP Medium 89	Medium recipe at CIP

Culture temp

@ref	Growth	Type	Temperature (°C)	Range
18055	positive	growth	37	mesophilic

Physiology and metabolism

Oxygen tolerance

@ref	Oxygen tolerance	Confidence
125439	facultative anaerobe	98.4

Spore formation

@ref	Spore formation	Confidence
125439		99.3
125438		96.361

Pathway annotation

Computationally determined by

@ref	pathway	enzyme coverage	annotated reactions
66794	CDP-diacylglycerol biosynthesis	100	2 of 2
66794	aspartate and asparagine metabolism	66.67	6 of 9
66794	glycolysis	52.94	9 of 17
66794	NAD metabolism	50	9 of 18
66794	acetate fermentation	50	2 of 4
66794	photosynthesis	50	7 of 14
66794	serine metabolism	44.44	4 of 9
66794	purine metabolism	38.3	36 of 94
66794	IAA biosynthesis	33.33	1 of 3
66794	selenocysteine biosynthesis	33.33	2 of 6
66794	L-lactaldehyde degradation	33.33	1 of 3
66794	pyrimidine metabolism	31.11	14 of 45
66794	oxidative phosphorylation	30.77	28 of 91
66794	reductive acetyl coenzyme A pathway	28.57	2 of 7
66794	pentose phosphate pathway	27.27	3 of 11
66794	6-hydroxymethyl-dihydropterin diphosphate biosynthesis	25	2 of 8
66794	lactate fermentation	25	1 of 4
66794	glycogen biosynthesis	25	1 of 4
66794	butanoate fermentation	25	1 of 4
66794	non-pathway related	23.68	9 of 38
66794	vitamin B1 metabolism	23.08	3 of 13
66794	methionine metabolism	23.08	6 of 26
66794	urea cycle	23.08	3 of 13
66794	d-mannose degradation	22.22	2 of 9

Isolation, sampling and environmental information

Isolation source categories

Cat1	Cat2	Cat3
#Infection	#Patient	-
#Host Body-Site	#Oral cavity and airways	-
#Host	#Human	#Child

Isolation

@ref	Sample type	Geographic location	Country	Country ISO 3 Code	Continent
18055	Oropharynx of child	Washington, DC	USA	USA	North America
121427	Human, Child, oropharynx	Washington, Washington	United States of America	USA	North America

Taxonmaps

69479

Global distribution of 16S sequence AY796060 (>99% sequence identity) for Mycoplasma from Microbeatlas

Aquatic Samples	118
Soil Samples	93
Animal Samples	7303
Plant Samples	70
Total Samples	7584

Interaction and safety

Risk assessment

@ref	Pathogenicity human	Biosafety level	Biosafety level comment
18055	yes, in single cases	1	Risk group (German classification) According to TRBA 466
121427		2	Risk group (French classification) According to TRBA 466

Sequence information

Genome sequences

@ref	Description	Assembly level	INSDC accession	BV-BRC accession	IMG accession	NCBI tax ID	Score
66792	50465_D02-3 assembly for Metamycoplasma orale NCTC10112	complete	GCA_900660435	2121.6	8067241083	2121	87.73
66792	ASM42010v1 assembly for Metamycoplasma orale ATCC 23714	contig	GCA_000420105	1266996.3	2523533589	1266996	68.24

16S sequences

@ref	Description	Accession	Length	NCBI tax ID
20218	Mycoplasma orale gene for 16S rRNA, partial sequence	AB069816	245	2121
20218	Mycoplasma orale 16S ribosomal RNA gene, partial sequence; 16S-23S ribosomal RNA intergenic spacer, complete sequence; and 23S ribosomal RNA gene, partial sequence	AY737010	882	2121
18055	Mycoplasma orale strain NC10112 16S ribosomal RNA gene, complete sequence	AY796060	1510	2121

Genome-based predictions

Predictions

Predictions from Deep Learning for Genome Sequence Data. R package version 0.3.1 based on: Metamycoplasma orale NCTC10112
NCBI: GCA_900660435

@ref	Trait	Model	Prediction	Confidence in %	In training data
125439	oxygen_tolerance	BacteriaNetⓘ	facultative anaerobe	98.40	no
125439	gram_stain	BacteriaNetⓘ	negative	99.70	no
125439	motility	BacteriaNetⓘ	no	60.20	no
125439	spore_formation	BacteriaNetⓘ	no	99.30	no

Predictions from bacterial phenotypic traits through improved machine learning using high-quality, curated datasets based on: Mycoplasma orale NCTC10112
NCBI: GCA_900660435.1

@ref	Trait	Model	Prediction	Confidence in %	In training data
125438	gram-positive	gram-positiveⓘ	yes	64.49	no
125438	anaerobic	anaerobicⓘ	no	82.90	no
125438	aerobic	aerobicⓘ	no	79.80	no
125438	spore-forming	spore-formingⓘ	no	96.36	no
125438	thermophilic	thermophileⓘ	no	97.74	no
125438	flagellated	motile2+ⓘ	no	94.93	no

Literature

Topic	Title	Authors	Journal	DOI	Year
Transcriptome	A PCR protocol to establish standards for routine mycoplasma testing that by design detects over ninety percent of all known mycoplasma species.	Siegl D, Kruchem M, Jansky S, Eichler E, Thies D, Hartwig U, Schuppan D, Bockamp E.	iScience	10.1016/j.isci.2023.106724	2023
	Osteomyelitis of the femur caused by Metamycoplasma orale in an immunocompromised patient using metagenomic next-generation sequencing: A case report.	Zhu H, Zhu J, Wang Y, Xi X, Wang K, Wang Y, Ding R, Li H.	Heliyon	10.1016/j.heliyon.2024.e28730	2024
	Correlation between Inflammasomes and Microbiota in Peri-Implantitis.	Padial-Molina M, Montalvo-Acosta S, Martin-Morales N, Perez-Carrasco V, Magan-Fernandez A, Mesa F, O'Valle F, Garcia-Salcedo JA, Galindo-Moreno P.	Int J Mol Sci	10.3390/ijms25020961	2024
	Meta-transcriptomics Reveals Dysbiosis of the Respiratory Microbiome in Older Adults with Long COVID	Liao M, Cai J, Zhu F, Lan Y, Xu T, Guo J, Xue Q, Wen Y, Zou F, Zhang Y, Zhang S, Yan Y, Ai J, Cui J, Zhang W.	Research (Wash D C)
Cultivation	SUPPRESSION OF ROUS SARCOMA VIRUS GROWTH IN TISSUE CULTURES BY MYCOPLASMA ORALE.	SOMERSON NL, COOK MK	J Bacteriol	10.1128/jb.90.2.534-540.1965	1965

References

#18055	Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 25590
#20215	Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 )
#20218	Verslyppe, B., De Smet, W., De Baets, B., De Vos, P., Dawyndt P.: StrainInfo introduces electronic passports for microorganisms.. Syst Appl Microbiol. 37: 42 - 50 2014 ( DOI 10.1016/j.syapm.2013.11.002 , PubMed 24321274 )
#66792	Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) .
#66794	Antje Chang, Lisa Jeske, Sandra Ulbrich, Julia Hofmann, Julia Koblitz, Ida Schomburg, Meina Neumann-Schaal, Dieter Jahn, Dietmar Schomburg: BRENDA, the ELIXIR core data resource in 2021: new developments and updates. Nucleic Acids Res. 49: D498 - D508 2020 ( DOI 10.1093/nar/gkaa1025 , PubMed 33211880 )
#69479	João F Matias Rodrigues, Janko Tackmann,Gregor Rot, Thomas SB Schmidt, Lukas Malfertheiner, Mihai Danaila,Marija Dmitrijeva, Daniela Gaio, Nicolas Näpflin and Christian von Mering. University of Zurich.: MicrobeAtlas 1.0 beta .
#121427	Collection of Institut Pasteur ; Curators of the CIP; CIP 104969
#125438	Julia Koblitz, Lorenz Christian Reimer, Rüdiger Pukall, Jörg Overmann: Predicting bacterial phenotypic traits through improved machine learning using high-quality, curated datasets. 2024 ( DOI 10.1101/2024.08.12.607695 )
#125439	Philipp Münch, René Mreches, Martin Binder, Hüseyin Anil Gündüz, Xiao-Yin To, Alice McHardy: deepG: Deep Learning for Genome Sequence Data. R package version 0.3.1 .
#126262	A. Lissin, I. Schober, J. F. Witte, H. Lüken, A. Podstawka, J. Koblitz, B. Bunk, P. Dawyndt, P. Vandamme, P. de Vos, J. Overmann, L. C. Reimer: StrainInfo—the central database for linked microbial strain identifiers. ( DOI 10.1093/database/baaf059 )

Rate our new design

Content

About us

Metamycoplasma orale (DSM 25590, ATCC 23714, CIP 104969)

Name and taxonomic classification

Morphology

Cell morphology

Colony morphology

Culture and growth conditions

Culture medium

Culture temp

Physiology and metabolism

Oxygen tolerance

Spore formation

Pathway annotation

Isolation, sampling and environmental information

Isolation source categories

Isolation

Taxonmaps

Interaction and safety

Risk assessment

Sequence information

Genome sequences

Genome browser: GCA_900660435

16S sequences

Genome-based predictions

Predictions

Literature

Literature

References

BacDive

Help

Social Media