Mycobacterium gilvum (DSM 45363, ATCC 43909, CCUG 57112)

Cell morphology

Multimedia

• @ref:	16412
  multimedia content:	DSM_45363.jpg
  multimedia.multimedia content:	https://www.dsmz.de/microorganisms/photos/DSM_45363.jpg
  caption:	Medium 645 37°C
  intellectual property rights:	© Leibniz-Institut DSMZ
  manual_annotation:	1

Culture medium

@ref	Name	Growth	Medium link	Composition
16412	MIDDLEBROOK MEDIUM (DSMZ Medium 645)		Medium recipe at MediaDive	Name: MIDDLEBROOK MEDIUM (DSMZ Medium 645) Composition: Bacto Middlebrook 7H10 agar 20.9945 g/l Glycerol Distilled water
36382	MEDIUM 55 - for Mycobacterium
119619	CIP Medium 55		Medium recipe at CIP

Culture temp

Oxygen tolerance

Metabolite utilization

@ref	Chebi-ID	Metabolite	Utilization activity	Kind of utilization tested
119619	606565 ChEBI	hippurate	-	hydrolysis
119619	17632 ChEBI	nitrate	+	reduction
119619	17632 ChEBI	nitrate	-	respiration
119619	16301 ChEBI	nitrite	-	reduction

Metabolite production

@ref	Chebi-ID	Metabolite	Production
119619	35581 ChEBI	indole

Enzymes

@ref	Value	Activity	Ec
68382	acid phosphatase	+	3.1.3.2	from API zym
68382	alkaline phosphatase	-	3.1.3.1	from API zym
68382	alpha-chymotrypsin	-	3.4.21.1	from API zym
68382	alpha-fucosidase	-	3.2.1.51	from API zym
68382	alpha-galactosidase	-	3.2.1.22	from API zym
68382	alpha-glucosidase	+	3.2.1.20	from API zym
68382	alpha-mannosidase	-	3.2.1.24	from API zym
68382	beta-galactosidase	-	3.2.1.23	from API zym
119619	beta-galactosidase	-	3.2.1.23
68382	beta-glucosidase	-	3.2.1.21	from API zym
68382	beta-glucuronidase	-	3.2.1.31	from API zym
119619	catalase	+	1.11.1.6
68382	cystine arylamidase	-	3.4.11.3	from API zym
68382	esterase (C 4)	+		from API zym
68382	esterase lipase (C 8)	+		from API zym
119619	gamma-glutamyltransferase	+	2.3.2.2
68382	leucine arylamidase	+	3.4.11.1	from API zym
68382	lipase (C 14)	-		from API zym
68382	N-acetyl-beta-glucosaminidase	-	3.2.1.52	from API zym
68382	naphthol-AS-BI-phosphohydrolase	+		from API zym
119619	oxidase	-
68382	trypsin	+	3.4.21.4	from API zym
119619	urease	-	3.5.1.5
68382	valine arylamidase	-		from API zym

API zym

Isolation source categories

Isolation

Risk assessment

Genome sequences

@ref	Description	Assembly level	INSDC accession	BV-BRC accession	IMG accession	NCBI tax ID	Score
67770	49243_C02 assembly for Mycolicibacterium gilvum NCTC10742	contig	GCA_900454025	1804.5	2871780381	1804	73.88
66792	ASM2582188v1 assembly for Mycolicibacterium gilvum DSM 45363	scaffold	GCA_025821885	1804.11	8113893131	1804	40.16

16S sequences

@ref	Description	Accession	Length	Database	NCBI tax ID
20218	M.gilvum 16S ribosomal RNA, part	X55599	1458		1804
20218	M.gilvum 16S rRNA gene	X81996	1428		1804
20218	Mycobacterium gilvum strain DSM 44503 16S ribosomal RNA gene, partial sequence	AF547929	540		1804

Predictions

Literature

Topic	Title	Authors	Journal	DOI	Year
Genetics	Rapid Identification of Mycobacterium tuberculosis Complex Using Mass Spectrometry: A Proof of Concept.	Robinne S, Saad J, Morsli M, Hamidou ZH, Tazerart F, Drancourt M, Baron SA.	Front Microbiol	10.3389/fmicb.2022.753969	2022
	In vitro and intracellular inhibitory activities of nosiheptide against Mycobacterium abscessus.	Zhu R, Yu X, Zhang T, Kong Y, Wang F, Jia J, Xue Y, Huang H.	Front Microbiol	10.3389/fmicb.2022.926361	2022
Metabolism	Transformation of the antibacterial agent norfloxacin by environmental mycobacteria.	Adjei MD, Heinze TM, Deck J, Freeman JP, Williams AJ, Sutherland JB.	Appl Environ Microbiol	10.1128/aem.03032-05	2006
Pathogenicity	In Vitro Activities of Bedaquiline and Delamanid against Nontuberculous Mycobacteria Isolated in Beijing, China.	Yu X, Gao X, Li C, Luo J, Wen S, Zhang T, Ma Y, Dong L, Wang F, Huang H.	Antimicrob Agents Chemother	10.1128/aac.00031-19	2019
Phylogeny	Biochip system for rapid and accurate identification of mycobacterial species from isolates and sputum.	Zhu L, Jiang G, Wang S, Wang C, Li Q, Yu H, Zhou Y, Zhao B, Huang H, Xing W, Mitchelson K, Cheng J, Zhao Y, Guo Y.	J Clin Microbiol	10.1128/jcm.00158-10	2010
Phylogeny	Phylogenomics and Comparative Genomic Studies Robustly Support Division of the Genus Mycobacterium into an Emended Genus Mycobacterium and Four Novel Genera.	Gupta RS, Lo B, Son J.	Front Microbiol	10.3389/fmicb.2018.00067	2018
Enzymology	Isolation of adherent polycyclic aromatic hydrocarbon (PAH)-degrading bacteria using PAH-sorbing carriers.	Bastiaens L, Springael D, Wattiau P, Harms H, deWachter R, Verachtert H, Diels L.	Appl Environ Microbiol	10.1128/aem.66.5.1834-1843.2000	2000
Phylogeny	Mycolic acid analysis by high-performance liquid chromatography for identification of Mycobacterium species.	Butler WR, Guthertz LS.	Clin Microbiol Rev	10.1128/cmr.14.4.704-726.2001	2001
Metabolism	Identification of a novel metabolite in the degradation of pyrene by Mycobacterium sp. strain AP1: actions of the isolate on two- and three-ring polycyclic aromatic hydrocarbons.	Vila J, Lopez Z, Sabate J, Minguillon C, Solanas AM, Grifoll M.	Appl Environ Microbiol	10.1128/aem.67.12.5497-5505.2001	2001
	Compilation of small ribosomal subunit RNA structures.	Neefs JM, Van de Peer Y, De Rijk P, Chapelle S, De Wachter R.	Nucleic Acids Res	10.1093/nar/21.13.3025	1993
	A Review on Adaption of Microbiomes to Polynuclear Aromatic Hydrocarbons: An Alternate Approach to Environment Sustainability.	Garg R, Dobhal K, Mukhopadhyay S.	Recent Pat Biotechnol	10.2174/0118722083343885250326070617	2025
Genetics	Metagenomics reveals mechanism of pyrene degradation by an enriched bacterial consortium from a coking site contaminated with PAHs.	Wang Q, Hou J, Huang Y, Liu W, Christie P.	Sci Total Environ	10.1016/j.scitotenv.2023.166759	2023
	Distribution patterns and influential factors of pathogenic bacteria in freshwater aquaculture sediments.	Xi W, Zhang X, Zhu X, Wang J, Xue H, Pan H.	Environ Sci Pollut Res Int	10.1007/s11356-024-31897-y	2024
Genetics	Nontuberculous Mycobacterial Pneumonia Caused by Mycobacterium immunogenum: A Case Report and Literature Review.	Huang S, Shangguan Y, Guo W, Ji Z, Jin X, Zhao R, Zheng L, Wang Y, Jiang L, Xu K.	Infect Drug Resist	10.2147/idr.s512539	2025
	Microbial degradation of pyrene in holm oak (Quercus ilex) phyllosphere: Role of particulate matter in regulating bioaccessibility.	Terzaghi E, Posada-Baquero R, Di Guardo A, Ortega-Calvo JJ.	Sci Total Environ	10.1016/j.scitotenv.2021.147431	2021
	Enhanced Bioremediation of Aged Polycyclic Aromatic Hydrocarbons in Soil Using Immobilized Microbial Consortia Combined with Strengthening Remediation Strategies.	Zhou H, Gao X, Wang S, Zhang Y, Coulon F, Cai C.	Int J Environ Res Public Health	10.3390/ijerph20031766	2023
	Enhanced phoxim biodegradation by immobilizing Novosphingobium sp. RL4 on attapulgite-sodium alginate.	Peng T, Huang Y, Yang T, Wang Y, Jin L.	Front Microbiol	10.3389/fmicb.2025.1541328	2025
Genetics	Clinicopathological characteristics and diagnostic performance of metagenomic pathogen detection technology in mycobacterial infections among HIV patients.	Li M, Chen J, Zhang L, Chen X, Zhou J, Liu F, Zhou X, Xiao J, Yang K, Qi L, Han X, Liu T, Zhao H, Zhou Z, Chen X, Sun L.	Front Cell Infect Microbiol	10.3389/fcimb.2025.1584189	2025
Phylogeny	Substrate-Induced Structural Dynamics and Evolutionary Linkage of Siderophore-Iron ABC Transporters of Mycobacterium tuberculosis.	Farhana A, Alsrhani A, Ejaz H, Alruwaili M, Alameen AAM, Manni E, Rasheed Z, Khan YS.	Medicina (Kaunas)	10.3390/medicina60111891	2024
Phylogeny	Evaluation of PyroMark Q24 pyrosequencing as a method for the identification of mycobacteria.	Chikamatsu K, Aono A, Hata H, Igarashi Y, Takaki A, Yamada H, Sakashita K, Mitarai S.	Diagn Microbiol Infect Dis	10.1016/j.diagmicrobio.2017.09.002	2018
Genetics	Characterization and Genome Analysis of the Delftia lacustris Strain LzhVag01 Isolated from Vaginal Discharge.	Zhang L, Zhang X, Bai H, Li T, Zhang Z, Zong X, Shang X, Liu Z, Fan L.	Curr Microbiol	10.1007/s00284-024-03758-x	2024
	Gold Panning-Related Chronic Cutaneous Ulcers in Guinea, West Africa.	Keita ML, Kaba A, Telly Diallo I, Kesso Bah M, Sagno M, Goumane A, Bouam A, Drancourt M.	Am J Trop Med Hyg	10.4269/ajtmh.22-0244	2023
Enzymology	Nucleic acid amplification techniques for rapid diagnosis of nontuberculous mycobacteria: A protocol of systematic review and meta-analysis.	Yu G, Shen Y, Xu X, Lin L.	PLoS One	10.1371/journal.pone.0250470	2021
Enzymology	Bioremediation of PAH-contaminated farmland: field experiment.	Ma L, Deng F, Yang C, Guo C, Dang Z.	Environ Sci Pollut Res Int	10.1007/s11356-016-7906-4	2018
Phylogeny	Detection of Mycobacterium gilvum first time from the bathing water of leprosy patient from Purulia, West Bengal.	Lavania M, Turankar R, Singh I, Nigam A, Sengupta U.	Int J Mycobacteriol	10.1016/j.ijmyco.2014.10.005	2014
Metabolism	Enhanced biodegradation of PAHs in historically contaminated soil by M. gilvum inoculated biochar.	Xiong B, Zhang Y, Hou Y, Arp HPH, Reid BJ, Cai C.	Chemosphere	10.1016/j.chemosphere.2017.05.020	2017
Genetics	Phylogenomic analyses and host range prediction of cluster P mycobacteriophages.	Howell AA, Versoza CJ, Cerna G, Johnston T, Kakde S, Karuku K, Kowal M, Monahan J, Murray J, Nguyen T, Sanchez Carreon A, Streiff A, Su B, Youkhana F, Munig S, Patel Z, So M, Sy M, Weiss S, Pfeifer SP.	G3 (Bethesda)	10.1093/g3journal/jkac244	2022
Metabolism	Toxic pyrene metabolism in Mycobacterium gilvum PYR-GCK results in the expression of mammalian cell entry genes as revealed by transcriptomics study.	Badejo AC, Chung WH, Kim NS, Kim SK, Chai JC, Lee YS, Jung KH, Kim HJ, Chai YG.	J Microbiol Biotechnol	10.4014/jmb.1311.11101	2014
Metabolism	A global proteome study of Mycobacterium gilvum PYR-GCK grown on pyrene and glucose reveals the activation of glyoxylate, shikimate and gluconeogenetic pathways through the central carbon metabolism highway.	Badejo AC, Choi CW, Badejo AO, Shin KH, Hyun JH, Lee YG, Kim SI, Park KS, Kim SH, Jung KH, Chung YH, Chai YG.	Biodegradation	10.1007/s10532-013-9622-9	2013
Metabolism	Accelerated biodegradation of pyrene and benzo[a]pyrene in the Phragmites australis rhizosphere by bacteria-root exudate interactions.	Toyama T, Furukawa T, Maeda N, Inoue D, Sei K, Mori K, Kikuchi S, Ike M.	Water Res	10.1016/j.watres.2010.11.044	2011
	Mycobacterium gilvum illustrates size-correlated relationships between mycobacteria and Acanthamoeba polyphaga.	Lamrabet O, Drancourt M.	Appl Environ Microbiol	10.1128/aem.03765-12	2013
	Complete genome sequence of Mycobacterium sp. strain (Spyr1) and reclassification to Mycobacterium gilvum Spyr1.	Kallimanis A, Karabika E, Mavromatis K, Lapidus A, Labutti KM, Liolios K, Ivanova N, Goodwin L, Woyke T, Velentzas AD, Perisynakis A, Ouzounis CC, Kyrpides NC, Koukkou AI, Drainas C.	Stand Genomic Sci	10.4056/sigs.2265047	2011
	Comparative genome analyses of mycobacteria give better insights into their evolution.	Wee WY, Dutta A, Choo SW.	PLoS One	10.1371/journal.pone.0172831	2017
Metabolism	Environmental metabolites of fluoroquinolones: synthesis, fractionation and toxicological assessment of some biologically active metabolites of ciprofloxacin.	Lewis G, Juhasz A, Smith E.	Environ Sci Pollut Res Int	10.1007/s11356-012-0766-7	2011
Metabolism	A gene expression study of the activities of aromatic ring-cleavage dioxygenases in Mycobacterium gilvum PYR-GCK to changes in salinity and pH during pyrene degradation.	Badejo AC, Badejo AO, Shin KH, Chai YG.	PLoS One	10.1371/journal.pone.0058066	2013
Enzymology	Energy metabolism in Mycobacterium gilvum PYR-GCK: insights from transcript expression analyses following two states of induction.	Badejo AC, Chung WH, Kim NS, Chai JC, Lee YS, Jung KH, Kim HJ, Chai YG.	PLoS One	10.1371/journal.pone.0099464	2014
Metabolism	Detection of antibacterial-like activity on a silica surface: fluoroquinolones and their environmental metabolites.	Lewis G, Juhasz A, Smith E.	Environ Sci Pollut Res Int	10.1007/s11356-012-0781-8	2011
Metabolism	Diversity of soil mycobacterium isolates from three sites that degrade polycyclic aromatic hydrocarbons.	Miller CD, Child R, Hughes JE, Benscai M, Der JP, Sims RC, Anderson AJ.	J Appl Microbiol	10.1111/j.1365-2672.2006.03202.x	2007
	Unveiling the Biosynthetic Pathway for Short Mycolic Acids in Nontuberculous Mycobacteria: Mycobacterium smegmatis MSMEG_4301 and Its Ortholog Mycobacterium abscessus MAB_1915 Are Essential for the Synthesis of alpha'-Mycolic Acids.	Di Capua CB, Belardinelli JM, Carignano HA, Buchieri MV, Suarez CA, Morbidoni HR.	Microbiol Spectr	10.1128/spectrum.01288-22	2022
Phylogeny	Characterization of IS1110-like sequences found in Mycobacterium species other than Mycobacterium avium.	Pagnout C, Ferard JF, Poupin P.	Res Microbiol	10.1016/j.resmic.2006.02.003	2006
Metabolism	Degradation of phenanthrene-analogue azaarenes by Mycobacterium gilvum strain LB307T under aerobic conditions.	Willumsen PA, Nielsen JK, Karlson U.	Appl Microbiol Biotechnol	10.1007/s002530100640	2001
Phylogeny	Mycobacterial Pan-Genome Analysis Suggests Important Role of Plasmids in the Radiation of Type VII Secretion Systems.	Dumas E, Christina Boritsch E, Vandenbogaert M, Rodriguez de la Vega RC, Thiberge JM, Caro V, Gaillard JL, Heym B, Girard-Misguich F, Brosch R, Sapriel G.	Genome Biol Evol	10.1093/gbe/evw001	2016
	Comparative analyses of nonpathogenic, opportunistic, and totally pathogenic mycobacteria reveal genomic and biochemical variabilities and highlight the survival attributes of Mycobacterium tuberculosis.	Rahman SA, Singh Y, Kohli S, Ahmad J, Ehtesham NZ, Tyagi AK, Hasnain SE.	mBio	10.1128/mbio.02020-14	2014
Enzymology	Characterization of non-tuberculous mycobacterium from humans and water in an Agropastoral area in Zambia.	Monde N, Munyeme M, Muwonge A, Muma JB, Malama S.	BMC Infect Dis	10.1186/s12879-017-2939-y	2018
	Genomic analysis of Mycobacterium brumae sustains its nonpathogenic and immunogenic phenotype.	Renau-Minguez C, Herrero-Abadia P, Ruiz-Rodriguez P, Sentandreu V, Torrents E, Chiner-Oms A, Torres-Puente M, Comas I, Julian E, Coscolla M.	Front Microbiol	10.3389/fmicb.2022.982679	2022
Pathogenicity	A combination of photodynamic therapy and antimicrobial compounds to treat skin and mucosal infections: a systematic review.	Perez-Laguna V, Gilaberte Y, Millan-Lou MI, Agut M, Nonell S, Rezusta A, Hamblin MR.	Photochem Photobiol Sci	10.1039/c8pp00534f	2019
	Modified clays alter diversity and respiration profile of microorganisms in long-term hydrocarbon and metal co-contaminated soil.	Biswas B, Juhasz AL, Mahmudur Rahman M, Naidu R.	Microb Biotechnol	10.1111/1751-7915.13510	2020
Phylogeny	Application of a broad-range resequencing array for detection of pathogens in desert dust samples from Kuwait and Iraq.	Leski TA, Malanoski AP, Gregory MJ, Lin B, Stenger DA.	Appl Environ Microbiol	10.1128/aem.00021-11	2011
	Global analyses of TetR family transcriptional regulators in mycobacteria indicates conservation across species and diversity in regulated functions.	Balhana RJ, Singla A, Sikder MH, Withers M, Kendall SL.	BMC Genomics	10.1186/s12864-015-1696-9	2015
Pathogenicity	The Effects of Fungicide, Soil Fumigant, Bio-Organic Fertilizer and Their Combined Application on Chrysanthemum Fusarium Wilt Controlling, Soil Enzyme Activities and Microbial Properties.	Zhao S, Chen X, Deng S, Dong X, Song A, Yao J, Fang W, Chen F.	Molecules	10.3390/molecules21040526	2016
Metabolism	High morpholine degradation rates and formation of cytochrome P450 during growth on different cyclic amines by newly isolated Mycobacterium sp. strain HE5.	Schrader T, Schuffenhauer G, Sielaff B, Andreesen JR.	Microbiology (Reading)	10.1099/00221287-146-5-1091	2000
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Metabolism	Structural and Functional Characterization of Phosphatidylinositol-Phosphate Biosynthesis in Mycobacteria.	Belcher Dufrisne M, Jorge CD, Timoteo CG, Petrou VI, Ashraf KU, Banerjee S, Clarke OB, Santos H, Mancia F.	J Mol Biol	10.1016/j.jmb.2020.04.028	2020
Metabolism	Comparative genomics of actinomycetes with a focus on natural product biosynthetic genes.	Doroghazi JR, Metcalf WW.	BMC Genomics	10.1186/1471-2164-14-611	2013
Pathogenicity	Antimicrobial susceptibility of standard strains of nontuberculous mycobacteria by microplate Alamar Blue assay.	Li G, Lian LL, Wan L, Zhang J, Zhao X, Jiang Y, Zhao LL, Liu H, Wan K.	PLoS One	10.1371/journal.pone.0084065	2013
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Genetics	Clusters of hairpins induce intrinsic transcription termination in bacteria.	Gupta S, Pal D.	Sci Rep	10.1038/s41598-021-95435-3	2021
	Identification of novel Mycobacterium tuberculosis CD4 T-cell antigens via high throughput proteome screening.	Nayak K, Jing L, Russell RM, Davies DH, Hermanson G, Molina DM, Liang X, Sherman DR, Kwok WW, Yang J, Kenneth J, Ahamed SF, Chandele A, Murali-Krishna K, Koelle DM.	Tuberculosis (Edinb)	10.1016/j.tube.2015.03.001	2015
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	Surface spreading motility shown by a group of phylogenetically related, rapidly growing pigmented mycobacteria suggests that motility is a common property of mycobacterial species but is restricted to smooth colonies.	Agusti G, Astola O, Rodriguez-Guell E, Julian E, Luquin M.	J Bacteriol	10.1128/jb.00572-08	2008
Genetics	Toward a Metagenomic Understanding on the Bacterial Composition and Resistome in Hong Kong Banknotes.	Heshiki Y, Dissanayake T, Zheng T, Kang K, Yueqiong N, Xu Z, Sarkar C, Woo PCY, Chow BKC, Baker D, Yan A, Webster CJ, Panagiotou G, Li J.	Front Microbiol	10.3389/fmicb.2017.00632	2017
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Pathogenicity	Effects of Polycyclic Aromatic Hydrocarbon Mixtures on Degradation, Gene Expression, and Metabolite Production in Four Mycobacterium Species.	Hennessee CT, Li QX.	Appl Environ Microbiol	10.1128/aem.00100-16	2016
Enzymology	Detection of Pathogenic and Non-pathogenic Bacteria in Drinking Water and Associated Biofilms on the Crow Reservation, Montana, USA.	Richards CL, Broadaway SC, Eggers MJ, Doyle J, Pyle BH, Camper AK, Ford TE.	Microb Ecol	10.1007/s00248-015-0595-6	2018
	Selection and validation of reference genes for gene expression studies in Klebsiella pneumoniae using Reverse Transcription Quantitative real-time PCR.	Gomes AEI, Stuchi LP, Siqueira NMG, Henrique JB, Vicentini R, Ribeiro ML, Darrieux M, Ferraz LFC.	Sci Rep	10.1038/s41598-018-27420-2	2018
Enzymology	Conserved Pro-Glu (PE) and Pro-Pro-Glu (PPE) protein domains target LipY lipases of pathogenic mycobacteria to the cell surface via the ESX-5 pathway.	Daleke MH, Cascioferro A, de Punder K, Ummels R, Abdallah AM, van der Wel N, Peters PJ, Luirink J, Manganelli R, Bitter W.	J Biol Chem	10.1074/jbc.m110.204966	2011
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Metabolism	Diversity, abundance, and consistency of microbial oxygenase expression and biodegradation in a shallow contaminated aquifer.	Yagi JM, Madsen EL.	Appl Environ Microbiol	10.1128/aem.01091-09	2009
	Deep sequencing reveals a novel closterovirus associated with wild rose leaf rosette disease.	He Y, Yang Z, Hong N, Wang G, Ning G, Xu W.	Mol Plant Pathol	10.1111/mpp.12202	2015
	The PPE domain of PPE17 is responsible for its surface localization and can be used to express heterologous proteins on the mycobacterial surface.	Dona V, Ventura M, Sali M, Cascioferro A, Provvedi R, Palu G, Delogu G, Manganelli R.	PLoS One	10.1371/journal.pone.0057517	2013
Enzymology	Pyrosequencing for rapid detection of extensively drug-resistant Mycobacterium tuberculosis in clinical isolates and clinical specimens.	Lin SY, Rodwell TC, Victor TC, Rider EC, Pham L, Catanzaro A, Desmond EP.	J Clin Microbiol	10.1128/jcm.01821-13	2014
Phylogeny	Non-tuberculous Mycobacteria in South African Wildlife: Neglected Pathogens and Potential Impediments for Bovine Tuberculosis Diagnosis.	Gcebe N, Hlokwe TM.	Front Cell Infect Microbiol	10.3389/fcimb.2017.00015	2017
Phylogeny	Assessment of genetic markers for species differentiation within the Mycobacterium tuberculosis complex.	Liebana E, Aranaz A, Francis B, Cousins D.	J Clin Microbiol	10.1128/jcm.34.4.933-938.1996	1996
Phylogeny	Numerical analysis of relationships among rapidly growing, scotochromogenic mycobacteria.	Tsukamura M, Mizuno S.	J Gen Microbiol	10.1099/00221287-98-2-511	1977
Metabolism	Elevated nitrate enriches microbial functional genes for potential bioremediation of complexly contaminated sediments.	Xu M, Zhang Q, Xia C, Zhong Y, Sun G, Guo J, Yuan T, Zhou J, He Z.	ISME J	10.1038/ismej.2014.42	2014
Enzymology	Reverse transcription-PCR detection of Mycobacterium leprae in clinical specimens.	Kurabachew M, Wondimu A, Ryon JJ.	J Clin Microbiol	10.1128/jcm.36.5.1352-1356.1998	1998
Metabolism	Enrichment, isolation, and phylogenetic identification of polycyclic aromatic hydrocarbon-degrading bacteria from Elizabeth River sediments.	Hilyard EJ, Jones-Meehan JM, Spargo BJ, Hill RT.	Appl Environ Microbiol	10.1128/aem.01518-07	2008
Genetics	Protein domain architectures provide a fast, efficient and scalable alternative to sequence-based methods for comparative functional genomics.	Koehorst JJ, Saccenti E, Schaap PJ, Martins Dos Santos VAP, Suarez-Diez M.	F1000Res	10.12688/f1000research.9416.3	2016
Metabolism	The structure of the oligomerization domain of Lsr2 from Mycobacterium tuberculosis reveals a mechanism for chromosome organization and protection.	Summers EL, Meindl K, Uson I, Mitra AK, Radjainia M, Colangeli R, Alland D, Arcus VL.	PLoS One	10.1371/journal.pone.0038542	2012
Metabolism	Osmotically induced synthesis of the dipeptide N-acetylglutaminylglutamine amide is mediated by a new pathway conserved among bacteria.	Sagot B, Gaysinski M, Mehiri M, Guigonis JM, Le Rudulier D, Alloing G.	Proc Natl Acad Sci U S A	10.1073/pnas.1003063107	2010
Metabolism	Different roles of DosS and DosT in the hypoxic adaptation of Mycobacteria.	Kim MJ, Park KJ, Ko IJ, Kim YM, Oh JI.	J Bacteriol	10.1128/jb.00550-10	2010
Phylogeny	Comparative sequence analysis of Mycobacterium leprae and the new leprosy-causing Mycobacterium lepromatosis.	Han XY, Sizer KC, Thompson EJ, Kabanja J, Li J, Hu P, Gomez-Valero L, Silva FJ.	J Bacteriol	10.1128/jb.00762-09	2009
Metabolism	The ESX-3 secretion system is necessary for iron and zinc homeostasis in Mycobacterium tuberculosis.	Serafini A, Pisu D, Palu G, Rodriguez GM, Manganelli R.	PLoS One	10.1371/journal.pone.0078351	2013
Metabolism	Activation of the eis gene in a W-Beijing strain of Mycobacterium tuberculosis correlates with increased SigA levels and enhanced intracellular growth.	Wu S, Barnes PF, Samten B, Pang X, Rodrigue S, Ghanny S, Soteropoulos P, Gaudreau L, Howard ST.	Microbiology (Reading)	10.1099/mic.0.024638-0	2009
Metabolism	Identification and characterization of the dicarboxylate uptake system DccT in Corynebacterium glutamicum.	Youn JW, Jolkver E, Kramer R, Marin K, Wendisch VF.	J Bacteriol	10.1128/jb.00780-08	2008
Metabolism	Using comparative genomics to uncover new kinds of protein-based metabolic organelles in bacteria.	Jorda J, Lopez D, Wheatley NM, Yeates TO.	Protein Sci	10.1002/pro.2196	2013
Enzymology	Isolation of nontuberculous mycobacteria in Zambia: eight case reports.	Buijtels PC, Petit PL, Verbrugh HA, van Belkum A, van Soolingen D.	J Clin Microbiol	10.1128/jcm.43.12.6020-6026.2005	2005
Metabolism	Strong impact on the polycyclic aromatic hydrocarbon (PAH)-degrading community of a PAH-polluted soil but marginal effect on PAH degradation when priming with bioremediated soil dominated by mycobacteria.	Johnsen AR, Schmidt S, Hybholt TK, Henriksen S, Jacobsen CS, Andersen O.	Appl Environ Microbiol	10.1128/aem.02236-06	2007
Metabolism	Phagosomal rupture by Mycobacterium tuberculosis results in toxicity and host cell death.	Simeone R, Bobard A, Lippmann J, Bitter W, Majlessi L, Brosch R, Enninga J.	PLoS Pathog	10.1371/journal.ppat.1002507	2012
Metabolism	The mycobacteriophage D29 gene 65 encodes an early-expressed protein that functions as a structure-specific nuclease.	Giri N, Bhowmik P, Bhattacharya B, Mitra M, Das Gupta SK.	J Bacteriol	10.1128/jb.00960-08	2009
	A study of some fast-growing scotochromogenic mycobacteria including species descriptions of Mycobacterium gilvum (new species) and Mycobacterium duv alii (new species).	Stanford JL, Gunthorpe WJ.	Br J Exp Pathol		1971
Metabolism	O2- and NO-sensing mechanism through the DevSR two-component system in Mycobacterium smegmatis.	Lee JM, Cho HY, Cho HJ, Ko IJ, Park SW, Baik HS, Oh JH, Eom CY, Kim YM, Kang BS, Oh JI.	J Bacteriol	10.1128/jb.00401-08	2008
	A widespread peroxiredoxin-like domain present in tumor suppression- and progression-implicated proteins.	Pawlowski K, Muszewska A, Lenart A, Szczepinska T, Godzik A, Grynberg M.	BMC Genomics	10.1186/1471-2164-11-590	2010
Enzymology	The Mycobacterium tuberculosis cytochrome P450 system.	Ouellet H, Johnston JB, Ortiz de Montellano PR.	Arch Biochem Biophys	10.1016/j.abb.2009.07.011	2010
Metabolism	Early gene duplication within chloroplastida and its correspondence with relocation of starch metabolism to chloroplasts.	Deschamps P, Moreau H, Worden AZ, Dauvillee D, Ball SG.	Genetics	10.1534/genetics.108.087205	2008
Metabolism	Two new Mycobacterium strains and their role in toluene degradation in a contaminated stream.	Tay ST, Hemond HF, Polz MF, Polz MF, Cavanaugh CM, Dejesus I, Krumholz LR.	Appl Environ Microbiol	10.1128/aem.64.5.1715-1720.1998	1998
Enzymology	Polymerase chain reaction for detection of Mycobacterium tuberculosis.	Sjobring U, Mecklenburg M, Andersen AB, Miorner H.	J Clin Microbiol	10.1128/jcm.28.10.2200-2204.1990	1990
Metabolism	Gene duplications in prokaryotes can be associated with environmental adaptation.	Bratlie MS, Johansen J, Sherman BT, Huang da W, Lempicki RA, Drablos F.	BMC Genomics	10.1186/1471-2164-11-588	2010
Metabolism	A blueprint of ectoine metabolism from the genome of the industrial producer Halomonas elongata DSM 2581 T.	Schwibbert K, Marin-Sanguino A, Bagyan I, Heidrich G, Lentzen G, Seitz H, Rampp M, Schuster SC, Klenk HP, Pfeiffer F, Oesterhelt D, Kunte HJ.	Environ Microbiol	10.1111/j.1462-2920.2010.02336.x	2011
Phylogeny	The RelA/SpoT homolog (RSH) superfamily: distribution and functional evolution of ppGpp synthetases and hydrolases across the tree of life.	Atkinson GC, Tenson T, Hauryliuk V.	PLoS One	10.1371/journal.pone.0023479	2011
Metabolism	Effect of model sorptive phases on phenanthrene biodegradation: molecular analysis of enrichments and isolates suggests selection based on bioavailability.	Friedrich M, Grosser RJ, Kern EA, Inskeep WP, Ward DM.	Appl Environ Microbiol	10.1128/aem.66.7.2703-2710.2000	2000
Phylogeny	A study of Mycobacterium gordonae and Mycobacterium marianum (Scrofulaceum).	Gunthorpe WJ, Stanford JL.	Br J Exp Pathol		1972
	A novel immunity system for bacterial nucleic acid degrading toxins and its recruitment in various eukaryotic and DNA viral systems.	Zhang D, Iyer LM, Aravind L.	Nucleic Acids Res	10.1093/nar/gkr036	2011
	A novel class of antimicrobial drugs selectively targets a Mycobacterium tuberculosis PE-PGRS protein.	Seo H, Kim S, Mahmud HA, Islam MI, Yoon Y, Cho HD, Nam KW, Choi J, Gil YS, Lee BE, Song HY.	PLoS Biol	10.1371/journal.pbio.3001648	2022
Metabolism	Acetylation and nitrosation of ciprofloxacin by environmental strains of mycobacteria.	Adjei MD, Heinze TM, Deck J, Freeman JP, Williams AJ, Sutherland JB	Can J Microbiol	10.1139/w06-101	2007
Phylogeny	Mycobacterium iranicum sp. nov., a rapidly growing scotochromogenic species isolated from clinical specimens on three different continents.	Shojaei H, Daley C, Gitti Z, Hashemi A, Heidarieh P, Moore ERB, Naser AD, Russo C, van Ingen J, Tortoli E.	Int J Syst Evol Microbiol	10.1099/ijs.0.043562-0	2013
Phylogeny	Mycobacterium insubricum sp. nov.	Tortoli E, Baruzzo S, Heijdra Y, Klenk HP, Lauria S, Mariottini A, van Ingen J.	Int J Syst Evol Microbiol	10.1099/ijs.0.003459-0	2009