Bacillus smithii (DSM 4216, IFO 15311, NBRC 15311)

Name: Bacillus smithii (DSM 4216, IFO 15311, NBRC 15311)
Creator: BacDive
License: http://creativecommons.org/licenses/by/4.0/

BacDive ID 815

Type strain

Strain Designation NRS-173

Culture col. no. DSM 4216 IFO 15311 NBRC 15311 NRRL NRS-173 CCUG 27413 5 more

NCBI tax ID(s) 1220590 1479

Special Collections DSMZ CCUG JCM CIP

History <- NRRL <- N.R. Smith (Bacillus coagulans) NRRL NRS-173 <-- N. R. Smith NRS-173. CIP <- 1993, L.K. Nakamura, NRRL, Bacillus coagulans <- N.R. Smith: strain NRS-173 <- R.E. Gordon, New Jersey Agri. Exper. Stat., New Brunswick, USA

Links

Bacillus smithii NRS-173 is an aerobe, thermophilic, Gram-positive prokaryote that was isolated from cheese.

Gram-positive motile rod-shaped aerobe thermophilic genome sequence 16S sequence

Name and taxonomic classification

SI-ID 7196

LMG 12526,CCUG 27413,CIP 103790,DSM 4216,IFO 15311,JCM 9076,NRRL NRS-173,KCTC 3618,NBRC 15311,NCIMB 13843,BCRC 15918,CCRC 15918,CGMCC 1.3752

@ref 20215

Last LPSN update 2026-02-09 11:17:57

Domain Bacteria

Phylum Bacillota

Class Bacilli

Order Caryophanales

Family Bacillaceae

Genus Bacillus

Species Bacillus smithii

Full scientific name Bacillus smithii Nakamura et al. 1988

BacDive ID	Other strains from **Bacillus smithii** (5)	Type strain
810	B. smithii E 28-66, DSM 459, CCUG 26018, LMG 6327, NRRL ...
811	B. smithii E 30-66, DSM 460
812	B. smithii 35-66, DSM 2319
813	B. smithii E 45-66, DSM 2320
814	B. smithii E 50-67, DSM 2321

Morphology

Cell morphology

@ref	Gram stain	Cell shape	Motility
122645	positive	rod-shaped

Colony morphology

48769

Incubation period1 day

Culture and growth conditions

Culture medium

@ref	Name	Medium link	Composition
1617	NUTRIENT AGAR (DSMZ Medium 1)	Medium recipe at MediaDive	Name: NUTRIENT AGAR (DSMZ Medium 1) Composition: Agar 15.0 g/l Peptone 5.0 g/l Meat extract 3.0 g/l Distilled water
40787	MEDIUM 3 - Columbia agar		Columbia agar (39.000 g);distilled water (1000.000 ml)
122645	CIP Medium 3	Medium recipe at CIP
122645	CIP Medium 72	Medium recipe at CIP

Culture temp

@ref	Growth	Type	Temperature (°C)	Range
1617	positive	growth	55	thermophilic
40787	positive	growth	55	thermophilic
48769	positive	growth	56	thermophilic
67770	positive	growth	55	thermophilic

Physiology and metabolism

Oxygen tolerance

48769

Oxygen toleranceaerobe

Spore formation

@ref	Spore formation	Confidence
125438		91.336
125439		90.6

Metabolite utilization

@ref	Chebi-ID	Metabolite	Utilization activity	Kind of utilization tested
68371	27613 ChEBI	amygdalin	-	builds acid from	from API 50CH acid
68368	27613 ChEBI	amygdalin	-	fermentation	from API 20E
68371	18305 ChEBI	arbutin	-	builds acid from	from API 50CH acid
68368	29016 ChEBI	arginine	-	hydrolysis	from API 20E
68371	17057 ChEBI	cellobiose	-	builds acid from	from API 50CH acid
68368	16947 ChEBI	citrate	-	assimilation	from API 20E
68371	17108 ChEBI	D-arabinose	-	builds acid from	from API 50CH acid
68371	18333 ChEBI	D-arabitol	-	builds acid from	from API 50CH acid
68371	15824 ChEBI	D-fructose	+	builds acid from	from API 50CH acid
68371	28847 ChEBI	D-fucose	-	builds acid from	from API 50CH acid
68371	12936 ChEBI	D-galactose	-	builds acid from	from API 50CH acid
68371	17634 ChEBI	D-glucose	+	builds acid from	from API 50CH acid
68368	17634 ChEBI	D-glucose	-	fermentation	from API 20E
68371	62318 ChEBI	D-lyxose	+	builds acid from	from API 50CH acid
68371	16899 ChEBI	D-mannitol	+	builds acid from	from API 50CH acid
68368	16899 ChEBI	D-mannitol	-	fermentation	from API 20E
68371	16024 ChEBI	D-mannose	-	builds acid from	from API 50CH acid
68371	16988 ChEBI	D-ribose	+	builds acid from	from API 50CH acid
68371	17924 ChEBI	D-sorbitol	-	builds acid from	from API 50CH acid
68371	16443 ChEBI	D-tagatose	+	builds acid from	from API 50CH acid
68371	65327 ChEBI	D-xylose	+	builds acid from	from API 50CH acid
68371	17113 ChEBI	erythritol	-	builds acid from	from API 50CH acid
68371	4853 ChEBI	esculin	-	builds acid from	from API 50CH acid
68371	16813 ChEBI	galactitol	-	builds acid from	from API 50CH acid
68368	5291 ChEBI	gelatin	+	hydrolysis	from API 20E
68371	28066 ChEBI	gentiobiose	-	builds acid from	from API 50CH acid
68371	24265 ChEBI	gluconate	+	builds acid from	from API 50CH acid
68371	17754 ChEBI	glycerol	+	builds acid from	from API 50CH acid
68371	28087 ChEBI	glycogen	-	builds acid from	from API 50CH acid
68371	15443 ChEBI	inulin	-	builds acid from	from API 50CH acid
68371	30849 ChEBI	L-arabinose	+	builds acid from	from API 50CH acid
68368	30849 ChEBI	L-arabinose	-	fermentation	from API 20E
68371	18403 ChEBI	L-arabitol	-	builds acid from	from API 50CH acid
68371	18287 ChEBI	L-fucose	-	builds acid from	from API 50CH acid
68371	62345 ChEBI	L-rhamnose	+	builds acid from	from API 50CH acid
68368	62345 ChEBI	L-rhamnose	-	fermentation	from API 20E
68371	17266 ChEBI	L-sorbose	-	builds acid from	from API 50CH acid
68371	65328 ChEBI	L-xylose	+	builds acid from	from API 50CH acid
68371	17716 ChEBI	lactose	-	builds acid from	from API 50CH acid
68368	25094 ChEBI	lysine	-	degradation	from API 20E
68371	17306 ChEBI	maltose	+	builds acid from	from API 50CH acid
68371	6731 ChEBI	melezitose	-	builds acid from	from API 50CH acid
68371	28053 ChEBI	melibiose	-	builds acid from	from API 50CH acid
68368	28053 ChEBI	melibiose	-	fermentation	from API 20E
68371	320061 ChEBI	methyl alpha-D-glucopyranoside	-	builds acid from	from API 50CH acid
68371	43943 ChEBI	methyl alpha-D-mannoside	-	builds acid from	from API 50CH acid
68371	74863 ChEBI	methyl beta-D-xylopyranoside	-	builds acid from	from API 50CH acid
68371	17268 ChEBI	myo-inositol	-	builds acid from	from API 50CH acid
68368	17268 ChEBI	myo-inositol	-	fermentation	from API 20E
68371	59640 ChEBI	N-acetylglucosamine	-	builds acid from	from API 50CH acid
68368	18257 ChEBI	ornithine	-	degradation	from API 20E
68371		Potassium 2-ketogluconate	-	builds acid from	from API 50CH acid
68371		Potassium 5-ketogluconate	+	builds acid from	from API 50CH acid
68371	16634 ChEBI	raffinose	-	builds acid from	from API 50CH acid
68371	15963 ChEBI	ribitol	-	builds acid from	from API 50CH acid
68371	17814 ChEBI	salicin	-	builds acid from	from API 50CH acid
68368	30911 ChEBI	sorbitol	-	fermentation	from API 20E
68371	28017 ChEBI	starch	-	builds acid from	from API 50CH acid
68371	17992 ChEBI	sucrose	-	builds acid from	from API 50CH acid
68368	17992 ChEBI	sucrose	-	fermentation	from API 20E
68371	27082 ChEBI	trehalose	+	builds acid from	from API 50CH acid
68368	27897 ChEBI	tryptophan	-	energy source	from API 20E
68371	32528 ChEBI	turanose	+	builds acid from	from API 50CH acid
68368	16199 ChEBI	urea	-	hydrolysis	from API 20E
68371	17151 ChEBI	xylitol	-	builds acid from	from API 50CH acid

Metabolite production

@ref	Chebi-ID	Metabolite
68368	15688 ChEBI	acetoin	from API 20E
68368	16136 ChEBI	hydrogen sulfide	from API 20E
68368	35581 ChEBI	indole	from API 20E

Metabolite tests

@ref	Chebi-ID	Metabolite	Voges-proskauer-test	Indole test
68368	15688 ChEBI	acetoin	-		from API 20E
68368	35581 ChEBI	indole		-	from API 20E

Enzymes

@ref	Value	Activity	Ec
68368	arginine dihydrolase	-	3.5.3.6	from API 20E
68368	beta-galactosidase	-	3.2.1.23	from API 20E
68368	cytochrome oxidase	-	1.9.3.1	from API 20E
68368	gelatinase	+		from API 20E
68368	lysine decarboxylase	-	4.1.1.18	from API 20E
68368	ornithine decarboxylase	-	4.1.1.17	from API 20E
68368	tryptophan deaminase	-	4.1.99.1	from API 20E
68368	urease	-	3.5.1.5	from API 20E

Pathway annotation

Computationally determined by

@ref	pathway	enzyme coverage	annotated reactions
66794	methylglyoxal degradation	100	5 of 5
66794	denitrification	100	2 of 2
66794	sulfopterin metabolism	100	4 of 4
66794	coenzyme A metabolism	100	4 of 4
66794	vitamin K metabolism	100	5 of 5
66794	palmitate biosynthesis	100	22 of 22
66794	ribulose monophosphate pathway	100	2 of 2
66794	L-lactaldehyde degradation	100	3 of 3
66794	cis-vaccenate biosynthesis	100	2 of 2
66794	CDP-diacylglycerol biosynthesis	100	2 of 2
66794	valine metabolism	100	9 of 9
66794	UDP-GlcNAc biosynthesis	100	3 of 3
66794	adipate degradation	100	2 of 2
66794	taurine degradation	100	1 of 1
66794	folate polyglutamylation	100	1 of 1
66794	aerobactin biosynthesis	100	1 of 1
66794	suberin monomers biosynthesis	100	2 of 2
66794	anapleurotic synthesis of oxalacetate	100	1 of 1
66794	tetrahydrofolate metabolism	92.86	13 of 14
66794	vitamin B1 metabolism	92.31	12 of 13
66794	pentose phosphate pathway	90.91	10 of 11
66794	propionate fermentation	90	9 of 10
66794	alanine metabolism	89.66	26 of 29
66794	molybdenum cofactor biosynthesis	88.89	8 of 9
66794	chorismate metabolism	88.89	8 of 9
66794	aspartate and asparagine metabolism	88.89	8 of 9
66794	gluconeogenesis	87.5	7 of 8
66794	C4 and CAM-carbon fixation	87.5	7 of 8
66794	isoleucine metabolism	87.5	7 of 8
66794	propanol degradation	85.71	6 of 7
66794	heme metabolism	85.71	12 of 14
66794	reductive acetyl coenzyme A pathway	85.71	6 of 7
66794	methionine metabolism	84.62	22 of 26
66794	leucine metabolism	84.62	11 of 13
66794	glutamate and glutamine metabolism	82.14	23 of 28
66794	flavin biosynthesis	80	12 of 15
66794	threonine metabolism	80	8 of 10
66794	peptidoglycan biosynthesis	80	12 of 15
66794	pyrimidine metabolism	80	36 of 45
66794	glycogen metabolism	80	4 of 5
66794	metabolism of amino sugars and derivatives	80	4 of 5
66794	cellulose degradation	80	4 of 5
66794	citric acid cycle	78.57	11 of 14
66794	photosynthesis	78.57	11 of 14
66794	allantoin degradation	77.78	7 of 9
66794	CO2 fixation in Crenarchaeota	77.78	7 of 9
66794	purine metabolism	76.6	72 of 94
66794	ppGpp biosynthesis	75	3 of 4
66794	biotin biosynthesis	75	3 of 4
66794	acetate fermentation	75	3 of 4
66794	ketogluconate metabolism	75	6 of 8
66794	glycogen biosynthesis	75	3 of 4
66794	phenol degradation	75	15 of 20
66794	degradation of sugar alcohols	75	12 of 16
66794	CMP-KDO biosynthesis	75	3 of 4
66794	tryptophan metabolism	73.68	28 of 38
66794	proline metabolism	72.73	8 of 11
66794	NAD metabolism	72.22	13 of 18
66794	cardiolipin biosynthesis	71.43	5 of 7
66794	non-pathway related	71.05	27 of 38
66794	glycolysis	70.59	12 of 17
66794	phenylalanine metabolism	69.23	9 of 13
66794	urea cycle	69.23	9 of 13
66794	lysine metabolism	69.05	29 of 42
66794	glycolate and glyoxylate degradation	66.67	4 of 6
66794	acetoin degradation	66.67	2 of 3
66794	octane oxidation	66.67	2 of 3
66794	enterobactin biosynthesis	66.67	2 of 3
66794	cyanate degradation	66.67	2 of 3
66794	formaldehyde oxidation	66.67	2 of 3
66794	acetyl CoA biosynthesis	66.67	2 of 3
66794	serine metabolism	66.67	6 of 9
66794	oxidative phosphorylation	62.64	57 of 91
66794	6-hydroxymethyl-dihydropterin diphosphate biosynthesis	62.5	5 of 8
66794	isoprenoid biosynthesis	61.54	16 of 26
66794	lipoate biosynthesis	60	3 of 5
66794	myo-inositol biosynthesis	60	6 of 10
66794	3-chlorocatechol degradation	60	3 of 5
66794	glycine betaine biosynthesis	60	3 of 5
66794	factor 420 biosynthesis	60	3 of 5
66794	starch degradation	60	6 of 10
66794	arginine metabolism	58.33	14 of 24
66794	degradation of pentoses	57.14	16 of 28
66794	d-mannose degradation	55.56	5 of 9
66794	histidine metabolism	55.17	16 of 29
66794	pantothenate biosynthesis	50	3 of 6
66794	toluene degradation	50	2 of 4
66794	androgen and estrogen metabolism	50	8 of 16
66794	Entner Doudoroff pathway	50	5 of 10
66794	degradation of hexoses	50	9 of 18
66794	4-hydroxyphenylacetate degradation	50	5 of 10
66794	cysteine metabolism	50	9 of 18
66794	degradation of aromatic, nitrogen containing compounds	50	6 of 12
66794	ethanol fermentation	50	1 of 2
66794	lipid metabolism	48.39	15 of 31
66794	sulfate reduction	46.15	6 of 13
66794	vitamin B6 metabolism	45.45	5 of 11
66794	nitrate assimilation	44.44	4 of 9
66794	polyamine pathway	43.48	10 of 23
66794	ubiquinone biosynthesis	42.86	3 of 7
66794	coenzyme M biosynthesis	40	4 of 10
66794	glycine metabolism	40	4 of 10
66794	phenylacetate degradation (aerobic)	40	2 of 5
66794	gallate degradation	40	2 of 5
66794	arachidonate biosynthesis	40	2 of 5
66794	3-phenylpropionate degradation	40	6 of 15
66794	phenylpropanoid biosynthesis	38.46	5 of 13
66794	d-xylose degradation	36.36	4 of 11
66794	metabolism of disaccharids	36.36	4 of 11
66794	ascorbate metabolism	36.36	8 of 22
66794	glutathione metabolism	35.71	5 of 14
66794	IAA biosynthesis	33.33	1 of 3
66794	selenocysteine biosynthesis	33.33	2 of 6
66794	(5R)-carbapenem carboxylate biosynthesis	33.33	1 of 3
66794	lipid A biosynthesis	33.33	3 of 9
66794	bile acid biosynthesis, neutral pathway	29.41	5 of 17
66794	tyrosine metabolism	28.57	4 of 14
66794	arachidonic acid metabolism	27.78	5 of 18
66794	dolichyl-diphosphooligosaccharide biosynthesis	27.27	3 of 11
66794	lactate fermentation	25	1 of 4
66794	cyclohexanol degradation	25	1 of 4
66794	butanoate fermentation	25	1 of 4
66794	dTDPLrhamnose biosynthesis	25	2 of 8

API 20E

@ref	ONPG	ADH (Arg)	LDC (Lys)	ODC	CIT	H2S productionH2S	URE	TDA (Trp)	IND	Acetoin production (Voges Proskauer test)VP	GEL	GLU	MAN	INO	Sor	RHA	SAC	MEL	AMY	ARA	OX	Nitrite productionNO2	Reduction to N2N2	MotilityMOB	Growth on MacConkey mediumMAC	OF-O	OF-F
48769	-	-	-	-	-	-	-	-	-	-	+	-	-	-	-	-	-	-	-	-	-	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.

API 50CHac

@ref	ControlQ	GLY	ERY	DARA	LARA	RIB	DXYL	LXYL	ADO	MDX	GAL	GLU	FRU	MNE	SBE	RHA	DUL	INO	MAN	SOR	MDM	MDG	NAG	AMY	ARB	ESC	SAL	CEL	MAL	LAC	MEL	SAC	TRE	INU	MLZ	RAF	AMD	GLYG	XLT	GEN	TUR	LYX	TAG	DFUC	LFUC	DARL	LARL	GNT	2KG	5KG
48769	-	+	-	-	+	+	+	+	-	-	-	+	+	-	-	+	-	-	+	-	-	-	-	-	-	-	-	-	+	-	-	-	+	-	-	-	-	-	-	-	+	+	+	-	-	-	-	+	-	+

Isolation, sampling and environmental information

Isolation source categories

Cat1	Cat2	Cat3
#Engineered	#Food production	#Dairy product

Isolation

@ref	Sample type	Country	Country ISO 3 Code	Continent	Isolation date
1617	cheese
48769	Cheese
67770	Cheese
122645	Food, Cheese	United States of America	USA	North America	1947

Taxonmaps

69479

Global distribution of 16S sequence Z26935 (>99% sequence identity) for Bacillus smithii subclade from Microbeatlas

Aquatic Samples	542
Soil Samples	1519
Animal Samples	1984
Plant Samples	562
Total Samples	4607

Interaction and safety

Risk assessment

@ref	Biosafety level	Biosafety level comment
1617	1	Risk group (German classification) According to TRBA 466
122645	1	Risk group (French classification) According to TRBA 466

Sequence information

Genome sequences

@ref	Description	Assembly level	INSDC accession	BV-BRC accession	IMG accession	NCBI tax ID	Score
66792	ASM105011v1 assembly for Bacillus smithii DSM 4216	complete	GCA_001050115	1479.5	2654588021	1479	97.85
67770	ASM159198v1 assembly for Bacillus smithii NBRC 15311	contig	GCA_001591985	1220590.3	2681812984	1220590	49.85

16S sequences

@ref	Description	Accession	Length	NCBI tax ID
20218	B.smithii 16S ribosomal RNA	X60643	1429	1479
20218	B.smithii gene for 16S ribosomal RNA	Z26935	1524	1479
20218	Bacillus smithii gene for 16S rRNA, partial sequence	AB006935	277	1479
20218	Bacillus smithii strain JCM9076 DNA for 16S ribosomal RNA, partial sequence	D78316	1437	1479
20218	Bacillus smithii gene for 16S rRNA, partial sequence	AB271749	1480	1479
67770	Bacillus smithii gene for 16S rRNA, partial sequence, strain: JCM 9076	LC379073	1477	1479

GC content

@ref	GC-content (mol%)	Method
1617	40.2
67770	38.7-39.7	Buoyant density centrifugation (BD)

Genome-based predictions

Predictions

Predictions from Deep Learning for Genome Sequence Data. R package version 0.3.1 based on: Bacillus smithii DSM 4216
NCBI: GCA_001050115

@ref	Trait	Model	Prediction	Confidence in %	In training data
125439	oxygen_tolerance	BacteriaNetⓘ	obligate aerobe	84.80	no
125439	gram_stain	BacteriaNetⓘ	variable	85.60	no
125439	motility	BacteriaNetⓘ	yes	85.10	no
125439	spore_formation	BacteriaNetⓘ	yes	90.60	no

Predictions from bacterial phenotypic traits through improved machine learning using high-quality, curated datasets based on: Bacillus smithii DSM 4216
NCBI: GCA_001050115.1

@ref	Trait	Model	Prediction	Confidence in %	In training data
125438	gram-positive	gram-positiveⓘ	yes	73.98	no
125438	anaerobic	anaerobicⓘ	no	88.35	yes
125438	aerobic	aerobicⓘ	yes	74.99	no
125438	spore-forming	spore-formingⓘ	yes	91.34	no
125438	thermophilic	thermophileⓘ	no	56.77	yes
125438	flagellated	motile2+ⓘ	yes	83.62	no

Literature

Topic	Title	Authors	Journal	DOI	Year
	Lactic Acid Production from Sugarcane Bagasse Hydrolysates by Lactiplantibacillus Strains.	Xavier MCA, Dias GS, Hernalsteens S, Franco TT.	ACS Omega	10.1021/acsomega.5c08221	2025
Metabolism	Conversion of levoglucosan into glucose by the coordination of four enzymes through oxidation, elimination, hydration, and reduction.	Kuritani Y, Sato K, Dohra H, Umemura S, Kitaoka M, Fushinobu S, Yoshida N.	Sci Rep	10.1038/s41598-020-77133-8	2020
Metabolism	Simultaneous saccharification and lactic acid fermentation of the cellulosic fraction of municipal solid waste using Bacillus smithii.	Chacon MG, Ibenegbu C, Leak DJ.	Biotechnol Lett	10.1007/s10529-020-03049-y	2021
Metabolism	Isolation of levoglucosan-utilizing thermophilic bacteria.	Iwazaki S, Hirai H, Hamaguchi N, Yoshida N.	Sci Rep	10.1038/s41598-018-22496-2	2018
	Iron-based microbial interactions: the role of iron metabolism in the cheese ecosystem.	Mekuli R, Shoukat M, Dugat-Bony E, Bonnarme P, Landaud S, Swennen D, Herve V.	J Bacteriol	10.1128/jb.00539-24	2025
	Comparison of Different Lactobacilli Regarding Substrate Utilization and Their Tolerance Towards Lignocellulose Degradation Products.	Gubelt A, Blaschke L, Hahn T, Rupp S, Hirth T, Zibek S.	Curr Microbiol	10.1007/s00284-020-02131-y	2020
Biotechnology	In vivo selection of sfGFP variants with improved and reliable functionality in industrially important thermophilic bacteria.	Frenzel E, Legebeke J, van Stralen A, van Kranenburg R, Kuipers OP.	Biotechnol Biofuels	10.1186/s13068-017-1008-5	2018
	Broad-Spectrum Antibacterial Action of Lipopeptides Derived from Bacillus smithii by Targeting Quorum Sensing.	Zhao N, Fan X, Sheas MN, Yu T, Yan F.	Probiotics Antimicrob Proteins	10.1007/s12602-025-10762-5	2025
	CLEAs of amidase from Bacillus smithii IIIMB2907: Development and application in hydroxamic acid synthesis.	Ganjoo A, Kumari H, Shafeeq H, Ayoub N, Ahmed Z, Babu V.	Int J Biol Macromol	10.1016/j.ijbiomac.2025.147312	2025
Biotechnology	Probiotic characterization of Bacillus smithii: Research advances, concerns, and prospective trends.	Zhao N, Huang X, Liu Z, Gao Y, Teng J, Yu T, Yan F.	Compr Rev Food Sci Food Saf	10.1111/1541-4337.13308	2024
	Nested Phosphorothioated Hybrid Primer-Mediated Isothermal Amplification for Specific and Dye-Based Subattomolar Nucleic Acid Detection at Low Temperatures.	Wang Y, Zhang L, Shen Y, Yu EY, Ding X.	ACS Sens	10.1021/acssensors.2c02754	2023
	Simultaneous saccharification and lactic acid fermentation of the cellulosic fraction of municipal solid waste using Bacillus smithii	Chacon MG, Ibenegbu C, Leak DJ.	Biotechnol Lett		2021
Metabolism	Structural and biochemical characterization of an extremely thermostable FMN-dependent NADH-indigo reductase from Bacillus smithii.	Yoneda K, Yoshioka M, Sakuraba H, Araki T, Ohshima T.	Int J Biol Macromol	10.1016/j.ijbiomac.2020.08.197	2020
Metabolism	Novel amidase catalysed process for the synthesis of vorinostat drug.	Singh RV, Sharma H, Ganjoo A, Kumar A, Babu V.	J Appl Microbiol	10.1111/jam.14753	2020
	Molecular Basis of Absorption at 340 nm of 3-Ketoglucosides under Alkaline Conditions.	Kitaoka M, Takano A, Takahashi M, Yamakawa Y, Fushinobu S, Yoshida N.	J Appl Glycosci (1999)	10.5458/jag.jag.jag-2023_0014	2024
Enzymology	Isolation, identification, and characterisation of the malachite green detoxifying bacterial strain Bacillus pacificus ROC1 and the azoreductase AzrC.	Bibi S, Breeze CW, Jadoon V, Fareed A, Syed A, Frkic RL, Zaffar H, Ali M, Zeb I, Jackson CJ, Naqvi TA.	Sci Rep	10.1038/s41598-024-84609-4	2025
Enzymology	A highly efficient method for genomic deletion across diverse lengths in thermophilic Parageobacillus thermoglucosidasius.	Yang Z, Li B, Bu R, Wang Z, Xin Z, Li Z, Zhang L, Wang W.	Synth Syst Biotechnol	10.1016/j.synbio.2024.05.009	2024
	Development of effective biotransformation process for benzohydroxamic acid production using Bacillus smithii IIIMB2907.	Sharma H, Singh RV, Ganjoo A, Kumar A, Singh R, Babu V.	3 Biotech	10.1007/s13205-022-03109-2	2022
	Microbial amidases: Characterization, advances and biotechnological applications.	Singh R, Shahul R, Kumar V, Yadav AK, Mehta PK.	Biotechnol Notes	10.1016/j.biotno.2024.12.003	2025
	Improving CRISPR-Cas9 Genome Editing Efficiency by Fusion with Chromatin-Modulating Peptides.	Ding X, Seebeck T, Feng Y, Jiang Y, Davis GD, Chen F.	CRISPR J	10.1089/crispr.2018.0036	2019
	Diverse thermophilic Bacillus species with multiple biotechnological activities are associated within the Egyptian soil and compost samples.	Zalma SA, El-Sharoud WM.	Sci Prog	10.1177/00368504211055277	2021
	Biodegradation of Polyhydroxybutyrate, Polylactide, and Their Blends by Microorganisms, Including Antarctic Species: Insights from Weight Loss, XRD, and Thermal Studies.	Skorokhoda V, Semeniuk I, Peretyatko T, Kochubei V, Ivanukh O, Melnyk Y, Stetsyshyn Y.	Polymers (Basel)	10.3390/polym17050675	2025
	Phylogenetic placement of thermophilic ammonium-tolerant bacteria and their distribution in various composts.	Kuroda K.	Anim Biosci	10.5713/ab.22.0216	2023
	Development of a Cas12a-Based Genome Editing Tool for Moderate Thermophiles.	Mohanraju P, Mougiakos I, Albers J, Mabuchi M, Fuchs RT, Curcuru JL, van Kranenburg R, Robb GB, van der Oost J.	CRISPR J	10.1089/crispr.2020.0086	2021
Metabolism	Large Fragment of DNA Polymerase I from Geobacillus sp. 777: Cloning and Comparison with DNA Polymerases I in Practical Applications.	Oscorbin IP, Boyarskikh UA, Filipenko ML.	Mol Biotechnol	10.1007/s12033-015-9886-x	2015
	Antimicrobial susceptibility test and antimicrobial resistance gene detection of extracellular enzyme bacteria isolated from tilapia (Oreochromis niloticus) for probiotic candidates.	Mawardi M, Indrawati A, Wibawan IWT, Lusiastuti AM.	Vet World	10.14202/vetworld.2023.264-271	2023
Phylogeny	Development of a systematic feedback isolation approach for targeted strains from mixed culture systems.	Poudel P, Tashiro Y, Miyamoto H, Miyamoto H, Okugawa Y, Sakai K.	J Biosci Bioeng	10.1016/j.jbiosc.2016.07.019	2017
	Inactivation of Bacillus spores in batch vs continuous heating systems at sterilisation temperatures	Stoeckel M, Abduh SBM, Atamer Z, Hinrichs J, Hinrichs J.	International journal of dairy technology.	10.1111/1471-0307.12134	2014
Metabolism	Detergent compatible alkaline lipase produced by marine Bacillus smithii BTMS 11.	Lailaja VP, Chandrasekaran M.	World J Microbiol Biotechnol	10.1007/s11274-013-1298-0	2013
	The Gram-Negative Bacilli Isolated from Caves-Sphingomonas paucimobilis and Hafnia alvei and a Review of Their Involvement in Human Infections.	Ionescu MI, Neagoe DS, Craciun AM, Moldovan OT.	Int J Environ Res Public Health	10.3390/ijerph19042324	2022
Metabolism	Exploiting composting biodiversity: study of the persistent and biotechnologically relevant microorganisms from lignocellulose-based composting.	Jurado M, Lopez MJ, Suarez-Estrella F, Vargas-Garcia MC, Lopez-Gonzalez JA, Moreno J.	Bioresour Technol	10.1016/j.biortech.2014.03.145	2014
	Probiotic potential of Lactobacillus plantarum DMR14 for preserving and extending shelf life of fruits and fruit juice.	Islam S, Biswas S, Jabin T, Moniruzzaman M, Biswas J, Uddin MS, Akhtar-E-Ekram M, Elgorban AM, Ghodake G, Syed A, Saleh MA, Zaman S.	Heliyon	10.1016/j.heliyon.2023.e17382	2023
	Efficient markerless genetic manipulation of Pasteurella multocida using lacZ and pheSm as selection markers.	Jiang J, Zhao Y, Chen A, Sun J, Zhou M, Hu J, Cao X, Dai N, Liang Z, Feng S.	Appl Environ Microbiol	10.1128/aem.02043-23	2024
	Microbial Synthesis of Lactic Acid from Cotton Stalk for Polylactic Acid Production.	Paswan M, Adhikary S, Salama HH, Rusu AV, Zuorro A, Dholakiya BZ, Trif M, Bhattacharya S.	Microorganisms	10.3390/microorganisms11081931	2023
Pathogenicity	Isolation and characterization of aerobic culturable arsenic-resistant bacteria from surfacewater and groundwater of Rautahat District, Nepal.	Shakya S, Pradhan B, Smith L, Shrestha J, Tuladhar S.	J Environ Manage	10.1016/j.jenvman.2011.08.001	2012
Biotechnology	Characterization of aerobic spore-forming bacteria associated with industrial dairy processing environments and product spoilage.	Lucking G, Stoeckel M, Atamer Z, Hinrichs J, Hinrichs J, Ehling-Schulz M.	Int J Food Microbiol	10.1016/j.ijfoodmicro.2013.07.004	2013
	Protective effect by Bacillus smithii TBMI12 spores of Salmonella serotype enteritidis in mice.	Suitso I, Jogi E, Talpsep E, Naaber P, Loivukene K, Ots ML, Michelson T, Nurk A.	Benef Microbes	10.3920/bm2008.1001	2010
	High-Performance PCR for Alleles Discrimination of Chromo-Helicase-DNA Binding Protein (CHD1) Gene in Bird Sexing.	Tagliavia M, Catania V, Dell'Omo G, Massa B.	Biology (Basel)	10.3390/biology12020300	2023
Enzymology	Characterization of thermo-stable endoinulinase from a new strain Bacillus smithii T7.	Gao W, Bao Y, Liu Y, Zhang X, Wang J, An L.	Appl Biochem Biotechnol	10.1007/s12010-008-8313-1	2009
Metabolism	An extended bacterial reductive pyrimidine degradation pathway that enables nitrogen release from beta-alanine.	Yin J, Wei Y, Liu D, Hu Y, Lu Q, Ang EL, Zhao H, Zhang Y.	J Biol Chem	10.1074/jbc.ra119.010406	2019
	Development of Real-Time and Colorimetric Loop Mediated Isothermal Amplification Assay for Detection of Xanthomonas gardneri.	Stehlikova D, Beran P, Cohen SP, Curn V.	Microorganisms	10.3390/microorganisms8091301	2020
	Update of the list of QPS-recommended biological agents intentionally added to food or feed as notified to EFSA 5: suitability of taxonomic units notified to EFSA until September 2016.	EFSA Panel on Biological Hazards (BIOHAZ), Ricci A, Allende A, Bolton D, Chemaly M, Davies R, Girones R, Koutsoumanis K, Herman L, Lindqvist R, Norrung B, Robertson L, Ru G, Sanaa M, Simmons M, Skandamis P, Snary E, Speybroeck N, Ter Kuile B, Threlfall J, Wahlstrom H, Cocconcelli PS, Klein Deceased G, Peixe L, Maradona MP, Querol A, Suarez JE, Sundh I, Vlak J, Correia S, Fernandez Escamez PS.	EFSA J	10.2903/j.efsa.2017.4663	2017
Biotechnology	Activating a dormant metabolic pathway for high-temperature l-alanine production in Bacillus licheniformis.	Han X, Liu J, Wu Y, Yang Y, Tao F, Xu P.	iScience	10.1016/j.isci.2023.106397	2023
	The effect of Bacillus coagulans on cytotoxicity and apoptosis induced by Salmonella Typhimurium in HT-29 cell culture.	Kawarizadeh A, Nojoomi F, Tabatabaei M, Hosseinzadeh S, Farzaneh M.	Iran J Microbiol	10.18502/ijm.v11i4.1468	2019
	CRISPR interference (CRISPRi) as transcriptional repression tool for Hungateiclostridium thermocellum DSM 1313.	Ganguly J, Martin-Pascual M, van Kranenburg R.	Microb Biotechnol	10.1111/1751-7915.13516	2020
	Coexistence of Heavy Metal Tolerance and Antibiotic Resistance in Thermophilic Bacteria Belonging to Genus Geobacillus.	Najar IN, Das S, Kumar S, Sharma P, Mondal K, Sherpa MT, Thakur N.	Front Microbiol	10.3389/fmicb.2022.914037	2022
	Additives Altered Bacterial Communities and Metabolic Profiles in Silage Hybrid Pennisetum.	Tian H, Zhu Y, Dai M, Li T, Guo Y, Deng M, Sun B.	Front Microbiol	10.3389/fmicb.2021.770728	2021
Enzymology	Isolation and Characterization of Levoglucosan-Metabolizing Bacteria.	Arya AS, Hang MTH, Eiteman MA.	Appl Environ Microbiol	10.1128/aem.01868-21	2022
	Response surface methodology: An effective optimization strategy for enhanced production of nitrile hydratase (NHase) by Rhodococcus rhodochrous (RS-6).	Sahu R, Meghavarnam AK, Janakiraman S.	Heliyon	10.1016/j.heliyon.2020.e05111	2020
	Disordered regions in proteusin peptides guide post-translational modification by a flavin-dependent RiPP brominase.	Nguyen NA, Vidya FNU, Yennawar NH, Wu H, McShan AC, Agarwal V.	Nat Commun	10.1038/s41467-024-45593-5	2024
Metabolism	A ferredoxin-dependent dihydropyrimidine dehydrogenase in Clostridium chromiireducens.	Wang F, Wei Y, Lu Q, Ang EL, Zhao H, Zhang Y.	Biosci Rep	10.1042/bsr20201642	2020
Enzymology	Crystal structure of nitrile hydratase from a thermophilic Bacillus smithii.	Hourai S, Miki M, Takashima Y, Mitsuda S, Yanagi K.	Biochem Biophys Res Commun	10.1016/j.bbrc.2003.10.124	2003
Enzymology	Thermophilic Nucleic Acid Polymerases and Their Application in Xenobiology.	Wang G, Du Y, Ma X, Ye F, Qin Y, Wang Y, Xiang Y, Tao R, Chen T.	Int J Mol Sci	10.3390/ijms232314969	2022
Phylogeny	Identification of thermophilic bacterial strains producing thermotolerant hydrolytic enzymes from manure compost.	Charbonneau DM, Meddeb-Mouelhi F, Boissinot M, Sirois M, Beauregard M.	Indian J Microbiol	10.1007/s12088-011-0156-8	2012
Pathogenicity	Evaluating the formulae for integrated lethality in ethylene oxide sterilization using six different endospore forming strains of bacteria, and comparisons of integrated lethality for ethylene oxide and steam systems.	Mosley GA, Gillis JR, Krushefski G.	PDA J Pharm Sci Technol		2005
Genetics	Metagenomics and Culture Dependent Insights into the Distribution of Firmicutes across Two Different Sample Types Located in the Black Hills Region of South Dakota, USA.	Govil T, Paste M, Samanta D, David A, Goh KM, Li X, Salem DR, Sani RK.	Microorganisms	10.3390/microorganisms9010113	2021
Stress	Engineering enhanced thermostability into the Geobacillus pallidus nitrile hydratase.	Van Wyk JC, Sewell BT, Danson MJ, Tsekoa TL, Sayed MF, Cowan DA.	Curr Res Struct Biol	10.1016/j.crstbi.2022.07.002	2022
	Isolation of a thermophilic poly-L-lactide degrading bacterium from compost and its enzymatic characterization.	Sakai K, Kawano H, Iwami A, Nakamura M, Moriguchi M.	J Biosci Bioeng	10.1263/jbb.92.298	2001
	Two-component carnitine monooxygenase from Escherichia coli: functional characterization, inhibition and mutagenesis of the molecular interface.	Piskol F, Neubauer K, Eggers M, Bode LM, Jasper J, Slusarenko A, Reijerse E, Lubitz W, Jahn D, Moser J.	Biosci Rep	10.1042/bsr20221102	2022
	Development of a Loop Mediated Isothermal Amplification for Diagnosis of Ascaris lumbricoides in Fecal Samples.	Shiraho EA, Eric AL, Mwangi IN, Maina GM, Kinuthia JM, Mutuku MW, Mugambi RM, Mwandi JM, Mkoji GM.	J Parasitol Res	10.1155/2016/7376207	2016
	Rapid detection of Mycoplasma synoviae by loop-mediated isothermal amplification.	Kursa O, Wozniakowski G, Tomczyk G, Sawicka A, Minta Z.	Arch Microbiol	10.1007/s00203-014-1063-2	2015
Metabolism	Characterizing a thermostable Cas9 for bacterial genome editing and silencing.	Mougiakos I, Mohanraju P, Bosma EF, Vrouwe V, Finger Bou M, Naduthodi MIS, Gussak A, Brinkman RBL, van Kranenburg R, van der Oost J.	Nat Commun	10.1038/s41467-017-01591-4	2017
	The Degradative Capabilities of New Amycolatopsis Isolates on Polylactic Acid.	Decorosi F, Exana ML, Pini F, Adessi A, Messini A, Giovannetti L, Viti C.	Microorganisms	10.3390/microorganisms7120590	2019
	Growth rate alterations of human colorectal cancer cells by 157 gut bacteria.	Taddese R, Garza DR, Ruiter LN, de Jonge MI, Belzer C, Aalvink S, Nagtegaal ID, Dutilh BE, Boleij A.	Gut Microbes	10.1080/19490976.2020.1799733	2020
Metabolism	FAD-dependent C-glycoside-metabolizing enzymes in microorganisms: Screening, characterization, and crystal structure analysis.	Kumano T, Hori S, Watanabe S, Terashita Y, Yu HY, Hashimoto Y, Senda T, Senda M, Kobayashi M.	Proc Natl Acad Sci U S A	10.1073/pnas.2106580118	2021
	Micropathogen Community Analysis in Hyalomma rufipes via High-Throughput Sequencing of Small RNAs.	Luo J, Liu MX, Ren QY, Chen Z, Tian ZC, Hao JW, Wu F, Liu XC, Luo JX, Yin H, Wang H, Liu GY.	Front Cell Infect Microbiol	10.3389/fcimb.2017.00374	2017
	Sequence of the gene encoding an alkaline serine protease of thermophilic Bacillus smithii.	Milano A, Manachini PL, Parini C, Riccardi G.	Gene	10.1016/0378-1119(94)90340-9	1994
Metabolism	Dynamic Changes in Microbial Communities and Physicochemical Characteristics During Fermentation of Non-post Fermented Shuidouchi.	Chen Y, Qin F, Dong M.	Front Nutr	10.3389/fnut.2022.926637	2022
Enzymology	Characterization and engineering of a DNA polymerase reveals a single amino-acid substitution in the fingers subdomain to increase strand-displacement activity of A-family prokaryotic DNA polymerases.	Piotrowski Y, Gurung MK, Larsen AN.	BMC Mol Cell Biol	10.1186/s12860-019-0216-1	2019
	Making soy sauce from defatted soybean meal without the mejus process by submerged cultivation using thermophilic bacteria.	Hur JM, Park DH.	J Food Sci Technol	10.1007/s13197-014-1536-y	2015
	Development of an efficient technique for gene deletion and allelic exchange in Geobacillus spp.	Bacon LF, Hamley-Bennett C, Danson MJ, Leak DJ.	Microb Cell Fact	10.1186/s12934-017-0670-4	2017
	Purification and partial characterization of bacillocin 490, a novel bacteriocin produced by a thermophilic strain of Bacillus licheniformis.	Martirani L, Varcamonti M, Naclerio G, De Felice M.	Microb Cell Fact	10.1186/1475-2859-1-1	2002
	Methods for Hydroxamic Acid Synthesis.	Alam MA.	Curr Org Chem	10.2174/1385272823666190424142821	2019
Phylogeny	The phylogenetic diversity of thermophilic members of the genus Bacillus as revealed by 16S rDNA analysis.	Rainey FA, Fritze D, Stackebrandt E.	FEMS Microbiol Lett	10.1111/j.1574-6968.1994.tb06639.x	1994
Genetics	Efficient genome editing of an extreme thermophile, Thermus thermophilus, using a thermostable Cas9 variant.	Adalsteinsson BT, Kristjansdottir T, Merre W, Helleux A, Dusaucy J, Tourigny M, Fridjonsson O, Hreggvidsson GO.	Sci Rep	10.1038/s41598-021-89029-2	2021
Metabolism	Production of a single cyclic type of fructooligosaccharide structure by inulin-degrading Paenibacillus sp. LX16 newly isolated from Jerusalem artichoke root.	Yao Z, Guo J, Tang W, Sun Z, Hou Y, Li X.	Microb Biotechnol	10.1111/1751-7915.12358	2016
Metabolism	Genetic detection of peste des petits ruminants virus under field conditions: a step forward towards disease eradication.	Ashraf W, Unger H, Haris S, Mobeen A, Farooq M, Asif M, Khan QM.	BMC Vet Res	10.1186/s12917-016-0940-0	2017
	Numerical analysis and DNA base compositions of some thermophilic Bacillus species.	De Bartolomeo A, Trotta F, La Rosa F, Saltalamacchia G, Mastrandrea V.	Int J Syst Bacteriol	10.1099/00207713-41-4-502	1991
Enzymology	Identification, functional characterization, and crystal structure determination of bacterial levoglucosan dehydrogenase.	Sugiura M, Nakahara M, Yamada C, Arakawa T, Kitaoka M, Fushinobu S.	J Biol Chem	10.1074/jbc.ra118.004963	2018
	Resistance to Enediyne Antitumor Antibiotics by Sequestration.	Chang CY, Yan X, Crnovcic I, Annaval T, Chang C, Nocek B, Rudolf JD, Yang D, Hindra, Babnigg G, Joachimiak A, Phillips GN, Shen B.	Cell Chem Biol	10.1016/j.chembiol.2018.05.012	2018
Phylogeny	Insights into the Geobacillus stearothermophilus species based on phylogenomic principles.	Burgess SA, Flint SH, Lindsay D, Cox MP, Biggs PJ.	BMC Microbiol	10.1186/s12866-017-1047-x	2017
Enzymology	Loop-mediated isothermal amplification for the detection of goose circovirus.	Wozniakowski G, Kozdrun W, Samorek-Salamonowicz E.	Virol J	10.1186/1743-422x-9-110	2012
Enzymology	Incidence and diversity of potentially highly heat-resistant spores isolated at dairy farms.	Scheldeman P, Pil A, Herman L, De Vos P, Heyndrickx M.	Appl Environ Microbiol	10.1128/aem.71.3.1480-1494.2005	2005
	Update of the list of QPS-recommended biological agents intentionally added to food or feed as notified to EFSA 8: suitability of taxonomic units notified to EFSA until March 2018.	EFSA Panel on Biological Hazards (BIOHAZ), Ricci A, Allende A, Bolton D, Chemaly M, Davies R, Fernandez Escamez PS, Girones R, Koutsoumanis K, Lindqvist R, Norrung B, Robertson L, Ru G, Sanaa M, Simmons M, Skandamis P, Snary E, Speybroeck N, Ter Kuile B, Threlfall J, Wahlstrom H, Cocconcelli PS, Peixe L, Maradona MP, Querol A, Suarez JE, Sundh I, Vlak J, Barizzone F, Correia S, Herman L.	EFSA J	10.2903/j.efsa.2018.5315	2018
	Update of the list of QPS-recommended biological agents intentionally added to food or feed as notified to EFSA 9: suitability of taxonomic units notified to EFSA until September 2018.	EFSA Panel on Biological Hazards (BIOHAZ), Koutsoumanis K, Allende A, Alvarez-Ordonez A, Bolton D, Bover-Cid S, Chemaly M, Davies R, Hilbert F, Lindqvist R, Nauta M, Peixe L, Ru G, Simmons M, Skandamis P, Suffredini E, Cocconcelli PS, Fernandez Escamez PS, Maradona MP, Querol A, Suarez JE, Sundh I, Vlak J, Barizzone F, Correia S, Herman L.	EFSA J	10.2903/j.efsa.2019.5555	2019
Phylogeny	The genetic diversity of genus Bacillus and the related genera revealed by 16s rRNA gene sequences and ardra analyses isolated from geothermal regions of turkey.	Cihan AC, Tekin N, Ozcan B, Cokmus C.	Braz J Microbiol	10.1590/s1517-838220120001000037	2012
	Update of the list of QPS-recommended biological agents intentionally added to food or feed as notified to EFSA 7: suitability of taxonomic units notified to EFSA until September 2017.	EFSA Panel on Biological Hazards (BIOHAZ), Ricci A, Allende A, Bolton D, Chemaly M, Davies R, Girones R, Koutsoumanis K, Lindqvist R, Norrung B, Robertson L, Ru G, Fernandez Escamez PS, Sanaa M, Simmons M, Skandamis P, Snary E, Speybroeck N, Ter Kuile B, Threlfall J, Wahlstrom H, Cocconcelli PS, Peixe L, Maradona MP, Querol A, Suarez JE, Sundh I, Vlak J, Barizzone F, Correia S, Herman L.	EFSA J	10.2903/j.efsa.2018.5131	2018
Enzymology	Evidence of the participation of remote residues in the catalytic activity of Co-type nitrile hydratase from Pseudomonas putida.	Brodkin HR, Novak WR, Milne AC, D'Aquino JA, Karabacak NM, Goldberg IG, Agar JN, Payne MS, Petsko GA, Ondrechen MJ, Ringe D.	Biochemistry	10.1021/bi101761e	2011
Metabolism	Cadmium ion biosorption by the thermophilic bacteria Geobacillus stearothermophilus and G. thermocatenulatus.	Hetzer A, Daughney CJ, Morgan HW.	Appl Environ Microbiol	10.1128/aem.00295-06	2006
Metabolism	Assessment of heat resistance of bacterial spores from food product isolates by fluorescence monitoring of dipicolinic acid release.	Kort R, O'Brien AC, van Stokkum IH, Oomes SJ, Crielaard W, Hellingwerf KJ, Brul S.	Appl Environ Microbiol	10.1128/aem.71.7.3556-3564.2005	2005
	Update of the list of QPS-recommended biological agents intentionally added to food or feed as notified to EFSA 10: Suitability of taxonomic units notified to EFSA until March 2019.	EFSA Panel on Biological Hazards (BIOHAZ), Koutsoumanis K, Allende A, Alvarez-Ordonez A, Bolton D, Bover-Cid S, Chemaly M, Davies R, De Cesare A, Hilbert F, Lindqvist R, Nauta M, Peixe L, Ru G, Simmons M, Skandamis P, Suffredini E, Cocconcelli PS, Fernandez Escamez PS, Maradona MP, Querol A, Suarez JE, Sundh I, Vlak J, Barizzone F, Correia S, Herman L.	EFSA J	10.2903/j.efsa.2019.5753	2019
	Fermentative Lactic Acid Production From Lignocellulosic Feedstocks: From Source to Purified Product.	Yankov D.	Front Chem	10.3389/fchem.2022.823005	2022
Pathogenicity	A Rapid Screening Method of Candidate Probiotics for Inflammatory Bowel Diseases and the Anti-inflammatory Effect of the Selected Strain Bacillus smithii XY1.	Huang X, Ai F, Ji C, Tu P, Gao Y, Wu Y, Yan F, Yu T	Front Microbiol	10.3389/fmicb.2021.760385	2021
Genetics	Complete genome sequence of thermophilic Bacillus smithii type strain DSM 4216(T).	Bosma EF, Koehorst JJ, van Hijum SA, Renckens B, Vriesendorp B, van de Weijer AH, Schaap PJ, de Vos WM, van der Oost J, van Kranenburg R	Stand Genomic Sci	10.1186/s40793-016-0172-8	2016
Metabolism	Establishment of markerless gene deletion tools in thermophilic Bacillus smithii and construction of multiple mutant strains.	Bosma EF, van de Weijer AH, van der Vlist L, de Vos WM, van der Oost J, van Kranenburg R	Microb Cell Fact	10.1186/s12934-015-0286-5	2015
Metabolism	Isolation and screening of thermophilic bacilli from compost for electrotransformation and fermentation: characterization of Bacillus smithii ET 138 as a new biocatalyst.	Bosma EF, van de Weijer AH, Daas MJ, van der Oost J, de Vos WM, van Kranenburg R	Appl Environ Microbiol	10.1128/AEM.03640-14	2015
Phylogeny	Bacillus lumedeiriae sp. nov., a Gram-Positive, Spore-Forming Rod Isolated from a Pharmaceutical Facility Production Environment and Added to the MALDI Biotyper^® Database.	Costa LVD, Ramos JN, Albuquerque LS, Miranda RVDSL, Valadao TB, Veras JFC, Vieira EMD, Forsythe S, Brandao MLL, Vieira VV.	Microorganisms	10.3390/microorganisms12122507	2024
Genetics	Bacillus kwashiorkori sp. nov., a new bacterial species isolated from a malnourished child using culturomics.	Seck EH, Beye M, Traore SI, Khelaifia S, Michelle C, Couderc C, Brah S, Fournier PE, Raoult D, Bittar F.	Microbiologyopen	10.1002/mbo3.535	2018
Phylogeny	Caldalkalibacillus thermarum gen. nov., sp. nov., a novel alkalithermophilic bacterium from a hot spring in China.	Xue Y, Zhang X, Zhou C, Zhao Y, Cowan DA, Heaphy S, Grant WD, Jones BE, Ventosa A, Ma Y	Int J Syst Evol Microbiol	10.1099/ijs.0.64105-0	2006
Phylogeny	Bacillus alveayuensis sp. nov., a thermophilic bacterium isolated from deep-sea sediments of the Ayu Trough.	Bae SS, Lee JH, Kim SJ	Int J Syst Evol Microbiol	10.1099/ijs.0.63424-0	2005

References

#1617	Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 4216
#20215	Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 )
#20218	Verslyppe, B., De Smet, W., De Baets, B., De Vos, P., Dawyndt P.: StrainInfo introduces electronic passports for microorganisms.. Syst Appl Microbiol. 37: 42 - 50 2014 ( DOI 10.1016/j.syapm.2013.11.002 , PubMed 24321274 )
#40787	; Curators of the CIP;
#48769	Culture Collection University of Gothenburg (CCUG) ; Curators of the CCUG; CCUG 27413
#66792	Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) .
#66794	Antje Chang, Lisa Jeske, Sandra Ulbrich, Julia Hofmann, Julia Koblitz, Ida Schomburg, Meina Neumann-Schaal, Dieter Jahn, Dietmar Schomburg: BRENDA, the ELIXIR core data resource in 2021: new developments and updates. Nucleic Acids Res. 49: D498 - D508 2020 ( DOI 10.1093/nar/gkaa1025 , PubMed 33211880 )
#67770	Japan Collection of Microorganism (JCM) ; Curators of the JCM;
#68368	Automatically annotated from API 20E .
#68371	Automatically annotated from API 50CH acid .
#69479	João F Matias Rodrigues, Janko Tackmann,Gregor Rot, Thomas SB Schmidt, Lukas Malfertheiner, Mihai Danaila,Marija Dmitrijeva, Daniela Gaio, Nicolas Näpflin and Christian von Mering. University of Zurich.: MicrobeAtlas 1.0 beta .
#122645	Collection of Institut Pasteur ; Curators of the CIP; CIP 103790
#125438	Julia Koblitz, Lorenz Christian Reimer, Rüdiger Pukall, Jörg Overmann: Predicting bacterial phenotypic traits through improved machine learning using high-quality, curated datasets. 2024 ( DOI 10.1101/2024.08.12.607695 )
#125439	Philipp Münch, René Mreches, Martin Binder, Hüseyin Anil Gündüz, Xiao-Yin To, Alice McHardy: deepG: Deep Learning for Genome Sequence Data. R package version 0.3.1 .
#126262	A. Lissin, I. Schober, J. F. Witte, H. Lüken, A. Podstawka, J. Koblitz, B. Bunk, P. Dawyndt, P. Vandamme, P. de Vos, J. Overmann, L. C. Reimer: StrainInfo—the central database for linked microbial strain identifiers. ( DOI 10.1093/database/baaf059 )

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Bacillus smithii (DSM 4216, IFO 15311, NBRC 15311)

Name and taxonomic classification

Morphology

Cell morphology

Colony morphology

Culture and growth conditions

Culture medium

Culture temp

Physiology and metabolism

Oxygen tolerance

Spore formation

Metabolite utilization

Metabolite production

Metabolite tests

Enzymes

Pathway annotation

API 20E

API 50CHac

Isolation, sampling and environmental information

Isolation source categories

Isolation

Taxonmaps

Interaction and safety

Risk assessment

Sequence information

Genome sequences

Genome browser: GCA_001050115

16S sequences

GC content

Genome-based predictions

Predictions

Literature

Literature

References

BacDive

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