Actinoplanes deccanensis A/10655 is a spore-forming bacterium that produces antibiotic compounds and was isolated from Soil.
antibiotic compound production spore-forming genome sequence 16S sequence Bacteria| @ref 20215 |
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| Domain Bacteria |
| Phylum Actinomycetota |
| Class Actinomycetes |
| Order Micromonosporales |
| Family Micromonosporaceae |
| Genus Actinoplanes |
| Species Actinoplanes deccanensis |
| Full scientific name Actinoplanes deccanensis Parenti et al. 1975 (Approved Lists 1980) |
| Synonyms (1) |
| BacDive ID | Other strains from Actinoplanes deccanensis (4) | Type strain |
|---|---|---|
| 100075 | A. deccanensis STI09053(IMET), 1028-003, | |
| 100076 | A. deccanensis STI09054(IMET), 1028-004, | |
| 100077 | A. deccanensis STI09055(IMET), 1028-005, | |
| 100078 | A. deccanensis STI09057(IMET), 1029-025, |
| @ref: | 11259 |
| multimedia content: | DSM_43806-1.jpg |
| multimedia.multimedia content: | https://www.dsmz.de/microorganisms/photos/DSM_43806-1.jpg |
| intellectual property rights: | © Leibniz-Institut DSMZ |
| manual_annotation: | 1 |
| @ref: | 11259 |
| multimedia content: | DSM_43806.jpg |
| multimedia.multimedia content: | https://www.dsmz.de/microorganisms/photos/DSM_43806.jpg |
| caption: | Medium 65 28°C |
| intellectual property rights: | © Leibniz-Institut DSMZ |
| manual_annotation: | 1 |
| @ref | Name | Growth | Medium link | Composition | |
|---|---|---|---|---|---|
| 11259 | GPHF-MEDIUM (DSMZ Medium 553) | Medium recipe at MediaDive | Name: GPHF-MEDIUM (DSMZ Medium 553) Composition: Agar 20.0 g/l Glucose 10.0 g/l Beef extract 5.0 g/l Yeast extract 5.0 g/l Casein peptone 5.0 g/l CaCl2 x 2 H2O 0.74 g/l Distilled water | ||
| 19591 | ISP 2 | Name: ISP 2 / Yeast Malt Agar (5265); 5265 Composition Malt extract 10.0 g/l Yeast extract 4.0 g/l Glucose 4.0 g/l Agar 15.0 g/l Preparation: Sterilisation: 20 minutes at 121°C pH before sterilisation: 7.0 Usage: Maintenance and Taxonomy Organisms: All Actinomycetes | |||
| 19591 | ISP 3 | Name: ISP 3; 5315 Composition Dog oat flakes 20.0 g/l Trace element solution (5314) 2.5 ml/l Agar 18.0 g/l Preparation: Oat flakes are cooked for 20 minutes, trace element solution and agar are added (in the case of non rolled oat flakes the suspension has to bee filtrated). Sterilisation: 20 minutes at 121°C pH before sterilisation: 7.8 Usage: Maintenance and taxonomy (e.g. SEM As liquid medium for metabolite production) Organisms: All Actinomycetes Trace element solution 5314 Name: Trace element solution 5314; 5314 Composition CaCl2 x H2O 3.0 g/l Fe-III-citrate 1.0 g/l MnSO4 0.2 g/l ZnCl2 0.1 g/l CuSO4 x 5 H2O 0.025 g/l Sodium tetra borate 0.2 g/l CoCl2 x 6 H2O 0.004 g/l Sodium molybdate 0.01 g/l Preparation: Use double destillated water. Sterilisation: 20 minutes at 121°C pH before sterilisation: Usage: Trace element solution for different media Organisms: | |||
| 19591 | ISP 4 | Name: ISP 4; DSM 547 Solution I: Difco soluble starch, 10.0 g. Make a paste of the starch with a small amount of cold distilled water and bring to a volume of 500 ml. Solution II: CaCO3 2.0 g K2HPO4 (anhydrous) 1.0 g MgSO4 x 7 H2O 1.0 g NaCl 1.0 g (NH4)2SO4 2.0 g Distilled water 500.0 ml Trace salt solution (see below) 1.0 ml The pH should be between 7.0 and 7.4. Do not adjust if it is within this range. Mix solutions I and II together. Add 20.0 g agar. Liquify agar by steaming at 100°C for 10 to 20 min. Trace element solution: FeSO4 x 7 H2O 0.1 g MnCl2 x 4 H2O 0.1 g ZnSO4 x 7 H2O 0.1 g Distilled water 100.0 ml | |||
| 19591 | ISP 5 | Name: ISP 5 (5323) Composition L-Asparagine 1.0 g/l Glycerol 10.0 g/l K2HPO4 1.0 g/l Salt solution (see preparation) 1.0 ml/l Agar 20.0 g/l Preparation: Salt solution 1.0 g FeSO4 x 7 H2O 1.0 g MnCl2 x 4 H2O 1.0 g ZNSO4 x 7 H2O in 100 ml water Sterilisation: 20 minutes at 121°C pH before sterilisation: 7.2 Usage: Maintenance and taxonomy Organisms: All Actinomycetes | |||
| 19591 | ISP 6 | Name: ISP 6 (5318) Composition Peptone 15.0 g/l Proteose peptose 5.0 g/l Ferric ammonium citrate 0.5 g/l Sodium glycerophosphate 1.0 g/l Sodium thiosulfate 0.08 g/l Yeast extract 1.0 g/l Agar 15.0 g/l Sterilisation: 20 minutes at 121°C pH before sterilisation: Usage: Production of melanoid pigments Organisms: All Actinomycetes | |||
| 19591 | ISP 7 | Name: ISP 7 (5322) Composition Glycerol 15.0 g/l L-Tyrosine 0.5 g/l L-Asparagine 1.0 g/l K2HPO4 0.5 g/l NaCl 0.5 g/l FeSO4 x 7 H2O 0.01 g/l Trace element solution 5343 1.0 ml/l Agar 20.0 Sterilisation: 20 minutes at 121°C pH before sterilisation: 7.3 Usage: Production of melanoid pigments Organisms: All Actinomycetes | |||
| 11259 | GYM STREPTOMYCES MEDIUM (DSMZ Medium 65) | Medium recipe at MediaDive | Name: GYM STREPTOMYCES MEDIUM (DSMZ Medium 65) Composition: Agar 18.0 g/l Malt extract 10.0 g/l Yeast extract 4.0 g/l Glucose 4.0 g/l CaCO3 2.0 g/l Distilled water |
| @ref | Oxygen tolerance | Confidence | |
|---|---|---|---|
| 125439 | obligate aerobe | 98.647 |
| @ref | Spore description | Type of spore | Spore formation | |
|---|---|---|---|---|
| 19591 | Formation of sporangia, spore surface smooth | spore |
| @ref | Salt | Growth | Tested relation | Concentration | |
|---|---|---|---|---|---|
| 19591 | NaCl | positive | maximum | 2.5 % |
| @ref | Chebi-ID | Metabolite | Utilization activity | Kind of utilization tested | |
|---|---|---|---|---|---|
| 68368 | 29016 ChEBI | arginine | - | hydrolysis | from API 20E |
| 68368 | 16947 ChEBI | citrate | + | assimilation | from API 20E |
| 68368 | 5291 ChEBI | gelatin | + | hydrolysis | from API 20E |
| 68368 | 25094 ChEBI | lysine | - | degradation | from API 20E |
| 68368 | 18257 ChEBI | ornithine | - | degradation | from API 20E |
| 68368 | 27897 ChEBI | tryptophan | - | energy source | from API 20E |
| 68368 | 16199 ChEBI | urea | - | hydrolysis | from API 20E |
| @ref | Value | Activity | Ec | |
|---|---|---|---|---|
| 68382 | acid phosphatase | + | 3.1.3.2 | from API zym |
| 68382 | alkaline phosphatase | + | 3.1.3.1 | from API zym |
| 68382 | alpha-chymotrypsin | + | 3.4.21.1 | from API zym |
| 68382 | alpha-fucosidase | - | 3.2.1.51 | from API zym |
| 68382 | alpha-galactosidase | + | 3.2.1.22 | from API zym |
| 68382 | alpha-glucosidase | + | 3.2.1.20 | from API zym |
| 68382 | alpha-mannosidase | + | 3.2.1.24 | from API zym |
| 68368 | arginine dihydrolase | - | 3.5.3.6 | from API 20E |
| 68382 | beta-galactosidase | + | 3.2.1.23 | from API zym |
| 68368 | beta-galactosidase | - | 3.2.1.23 | from API 20E |
| 68382 | beta-glucosidase | + | 3.2.1.21 | from API zym |
| 68382 | beta-glucuronidase | + | 3.2.1.31 | from API zym |
| 68382 | cystine arylamidase | - | 3.4.11.3 | from API zym |
| 68382 | esterase (C 4) | + | from API zym | |
| 68382 | esterase lipase (C 8) | + | from API zym | |
| 68368 | gelatinase | + | from API 20E | |
| 68382 | leucine arylamidase | + | 3.4.11.1 | from API zym |
| 68382 | lipase (C 14) | - | from API zym | |
| 68368 | lysine decarboxylase | - | 4.1.1.18 | from API 20E |
| 68382 | N-acetyl-beta-glucosaminidase | + | 3.2.1.52 | from API zym |
| 68382 | naphthol-AS-BI-phosphohydrolase | + | from API zym | |
| 68368 | ornithine decarboxylase | - | 4.1.1.17 | from API 20E |
| 68382 | trypsin | + | 3.4.21.4 | from API zym |
| 68368 | tryptophan deaminase | - | 4.1.99.1 | from API 20E |
| 68368 | urease | - | 3.5.1.5 | from API 20E |
| 68382 | valine arylamidase | - | from API zym |
| @ref | Sample type | Geographic location | Country | Country ISO 3 Code | Continent | |
|---|---|---|---|---|---|---|
| 67770 | Soil | Decca | India | IND | Asia |
Global distribution of 16S sequence AB036998 (>99% sequence identity) for Actinoplanes from Microbeatlas ![]()
| @ref | Description | Assembly level | INSDC accession | BV-BRC accession | IMG accession | NCBI tax ID | Score | |
|---|---|---|---|---|---|---|---|---|
| 66792 | ASM1686211v1 assembly for Paractinoplanes deccanensis NBRC 13994 | contig | 113561 | 23.15 |
| @ref | Description | Accession | Length | Database | NCBI tax ID | |
|---|---|---|---|---|---|---|
| 20218 | Actinoplanes deccanensis gene for 16S rRNA, partial sequence | AB036998 | 1477 | 113561 | ||
| 20218 | Actinoplanes deccanensis partial 16S rRNA gene, strain IMSNU 20026T | AJ277565 | 1452 | 113561 | ||
| 124043 | Actinoplanes deccanensis strain JCM 3247 16S ribosomal RNA gene, partial sequence. | MT760428 | 1190 | 113561 |
| @ref | Trait | Model | Prediction | Confidence in % | In training data |
|---|---|---|---|---|---|
| 125439 | oxygen_tolerance | BacteriaNetⓘ | obligate aerobe | 98.65 | no |
| 125439 | gram_stain | BacteriaNetⓘ | positive | 99.44 | no |
| 125439 | motility | BacteriaNetⓘ | no | 92.16 | no |
| 125439 | spore_formation | BacteriaNetⓘ | yes | 88.15 | no |
| @ref | Trait | Model | Prediction | Confidence in % | In training data |
|---|---|---|---|---|---|
| 125438 | gram-positive | gram-positiveⓘ | yes | 88.95 | no |
| 125438 | anaerobic | anaerobicⓘ | no | 93.36 | no |
| 125438 | spore-forming | spore-formingⓘ | yes | 87.45 | no |
| 125438 | aerobic | aerobicⓘ | yes | 87.14 | no |
| 125438 | thermophilic | thermophileⓘ | no | 95.75 | no |
| 125438 | flagellated | motile2+ⓘ | no | 59.33 | no |
| Topic | Title | Authors | Journal | DOI | Year | |
|---|---|---|---|---|---|---|
| Final Demonstration of the Co-Identity of Lipiarmycin A3 and Tiacumicin B (Fidaxomicin) through Single Crystal X-ray Analysis. | Serra S, Malpezzi L, Bedeschi A, Fuganti C, Fonte P. | Antibiotics (Basel) | 10.3390/antibiotics6010007 | 2017 | ||
| Pathogenicity | Structural Basis of Transcription Inhibition by Fidaxomicin (Lipiarmycin A3). | Lin W, Das K, Degen D, Mazumder A, Duchi D, Wang D, Ebright YW, Ebright RY, Sineva E, Gigliotti M, Srivastava A, Mandal S, Jiang Y, Liu Y, Yin R, Zhang Z, Eng ET, Thomas D, Donadio S, Zhang H, Zhang C, Kapanidis AN, Ebright RH. | Mol Cell | 10.1016/j.molcel.2018.02.026 | 2018 | |
| Improving fidaxomicin production through ARTP mutagenesis and fermentation optimization in Actinoplanes deccanensis. | Ruan JY, Xie H, Zheng YL, Zhao QW, Chen XA, Lyu ZY, Li YQ. | Synth Syst Biotechnol | 10.1016/j.synbio.2025.06.002 | 2025 | ||
| Genetics | Stepwise increase of fidaxomicin in an engineered heterologous host Streptomyces albus through multi-level metabolic engineering. | Xie H, Su YT, Bu QT, Li YP, Zhao QW, Du YL, Li YQ. | Synth Syst Biotechnol | 10.1016/j.synbio.2024.06.004 | 2024 | |
| Transcriptome | Transcriptional regulation of the fidaxomicin gene cluster and cellular development in Actinoplanes deccanensis YP-1 by the pleiotropic regulator MtrA. | Xie H, Ruan J-Y, Bu Q-T, Li Y-P, Su Y-T, Zhao Q-W, Du Y-L, Li Y-Q. | Microbiol Spectr | 10.1128/spectrum.02702-23 | 2023 | |
| Genome-based rational engineering of Actinoplanes deccanensis for improving fidaxomicin production and genetic stability. | Li YP, Bu QT, Li JF, Xie H, Su YT, Du YL, Li YQ. | Bioresour Technol | 10.1016/j.biortech.2021.124982 | 2021 | ||
| Polyamine-producing actinobacteria enhance biomass production and seed yield in Salicornia bigelovii | El-Tarabily KA, ElBaghdady KZ, AlKhajeh AS, Ayyash MM, Aljneibi RS, El-Keblawy A, AbuQamar SF. | Biol Fertil Soils | 10.1007/s00374-020-01450-3 | 2020 | ||
| The Co-identity of Lipiarmycin A3 and Tiacumicin B. | Bedeschi A, Fonte P, Fronza G, Fuganti C, Serra S. | Nat Prod Commun | 10.1177/1934578x1400900227 | 2016 | ||
| Comparison of fidaxomicin, thuricin CD, vancomycin and nisin highlights the narrow spectrum nature of thuricin CD. | Walsh L, Lavelle A, O'Connor PM, Hill C, Ross RP. | Gut Microbes | 10.1080/19490976.2024.2342583 | 2024 | ||
| Salicornia bigelovii, S. brachiata and S. herbacea: Their Nutritional Characteristics and an Evaluation of Their Potential as Salt Substitutes. | Alfheeaid HA, Raheem D, Ahmed F, Alhodieb FS, Alsharari ZD, Alhaji JH, BinMowyna MN, Saraiva A, Raposo A. | Foods | 10.3390/foods11213402 | 2022 | ||
| Enhancing tylosin production by combinatorial overexpression of efflux, SAM biosynthesis, and regulatory genes in hyperproducing Streptomyces xinghaiensis strain. | Dai P, Qin Y, Li L, Li H, Lv L, Xu D, Song Y, Huang T, Lin S, Deng Z, Tao M. | Synth Syst Biotechnol | 10.1016/j.synbio.2023.07.002 | 2023 | ||
| Enzymology | Fidaxomicin for the treatment of Clostridioides difficile in children. | Skinner AM, Scardina T, Kociolek LK. | Future Microbiol | 10.2217/fmb-2020-0104 | 2020 | |
| Transcriptome | Multi-omics Comparative Analysis of Streptomyces Mutants Obtained by Iterative Atmosphere and Room-Temperature Plasma Mutagenesis. | Liu T, Huang Z, Gui X, Xiang W, Jin Y, Chen J, Zhao J. | Front Microbiol | 10.3389/fmicb.2020.630309 | 2020 | |
| Halotolerant Marine Rhizosphere-Competent Actinobacteria Promote Salicornia bigelovii Growth and Seed Production Using Seawater Irrigation. | Mathew BT, Torky Y, Amin A, Mourad AI, Ayyash MM, El-Keblawy A, Hilal-Alnaqbi A, AbuQamar SF, El-Tarabily KA. | Front Microbiol | 10.3389/fmicb.2020.00552 | 2020 | ||
| Substrate Specificity of Acyltransferase Domains for Efficient Transfer of Acyl Groups. | Shen JJ, Chen F, Wang XX, Liu XF, Chen XA, Mao XM, Li YQ. | Front Microbiol | 10.3389/fmicb.2018.01840 | 2018 | ||
| Metabolism | Lipiarmycin, a new antibiotic from Actinoplanes. I. Description of the producer strain and fermentation studies. | Parenti F, Pagani H, Beretta G. | J Antibiot (Tokyo) | 10.7164/antibiotics.28.247 | 1975 | |
| Lipiarmycin, a new antibiotic from Actinoplanes. II. Isolation, chemical, biological and biochemical characterization. | Coronelli C, White RJ, Lancini GC, Parenti F. | J Antibiot (Tokyo) | 10.7164/antibiotics.28.253 | 1975 | ||
| Pathogenicity | New target for inhibition of bacterial RNA polymerase: 'switch region'. | Srivastava A, Talaue M, Liu S, Degen D, Ebright RY, Sineva E, Chakraborty A, Druzhinin SY, Chatterjee S, Mukhopadhyay J, Ebright YW, Zozula A, Shen J, Sengupta S, Niedfeldt RR, Xin C, Kaneko T, Irschik H, Jansen R, Donadio S, Connell N, Ebright RH. | Curr Opin Microbiol | 10.1016/j.mib.2011.07.030 | 2011 | |
| Pathogenicity | The transcription inhibitor lipiarmycin blocks DNA fitting into the RNA polymerase catalytic site. | Tupin A, Gualtieri M, Leonetti JP, Brodolin K. | EMBO J | 10.1038/emboj.2010.135 | 2010 | |
| Metabolism | GE23077 binds to the RNA polymerase 'i' and 'i+1' sites and prevents the binding of initiating nucleotides. | Zhang Y, Degen D, Ho MX, Sineva E, Ebright KY, Ebright YW, Mekler V, Vahedian-Movahed H, Feng Y, Yin R, Tuske S, Irschik H, Jansen R, Maffioli S, Donadio S, Arnold E, Ebright RH. | Elife | 10.7554/elife.02450 | 2014 | |
| Enzymology | Structure and biological activity of lipiarmycin B. | Cavalleri B, Arnone A, Di Modugno E, Nasini G, Goldstein BP | J Antibiot (Tokyo) | 10.7164/antibiotics.41.308 | 1988 | |
| Phylogeny | Actinoplanes toevensis sp. nov. and Actinoplanes tereljensis sp. nov., isolated from Mongolian soil. | Ara I, Yamamura H, Tsetseg B, Daram D, Ando K. | Int J Syst Evol Microbiol | 10.1099/ijs.0.009944-0 | 2010 | |
| Phylogeny | Actinoplanes sediminis sp. nov., isolated from marine sediment. | Qu Z, Bao XD, Xie QY, Zhao YX, Yan B, Dai HF, Chen HQ | Int J Syst Evol Microbiol | 10.1099/ijsem.0.002451 | 2017 | |
| Phylogeny | Classification of Actinoplanes sp. ATCC 33076, an actinomycete that produces the glycolipodepsipeptide antibiotic ramoplanin, as Actinoplanes ramoplaninifer sp. nov. | Marcone GL, Binda E, Reguzzoni M, Gastaldo L, Dalmastri C, Marinelli F | Int J Syst Evol Microbiol | 10.1099/ijsem.0.002281 | 2017 | |
| Phylogeny | Actinoplanes atraurantiacus sp. nov., isolated from soil. | Zhang Y, Zhang J, Fan L, Pang H, Xin Y, Zhang X | Int J Syst Evol Microbiol | 10.1099/ijs.0.037226-0 | 2011 | |
| Phylogeny | Actinoplanes abujensis sp. nov., isolated from Nigerian arid soil. | Sazak A, Sahin N, Camas M | Int J Syst Evol Microbiol | 10.1099/ijs.0.031872-0 | 2011 |
| #11259 | Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 43806 |
| #19591 | Wink, J.: Compendium of Actinobacteria. HZI-Helmholtz-Centre for Infection Research, Braunschweig . |
| #20215 | Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 ) |
| #20216 | Curators of the JMRC: Jena Microbial Resource Collection (JMRC): |
| #20218 | Verslyppe, B., De Smet, W., De Baets, B., De Vos, P., Dawyndt P.: StrainInfo introduces electronic passports for microorganisms.. Syst Appl Microbiol. 37: 42 - 50 2014 ( DOI 10.1016/j.syapm.2013.11.002 , PubMed 24321274 ) |
| #66792 | Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) . |
| #67770 | Japan Collection of Microorganism (JCM) ; Curators of the JCM; |
| #68368 | Automatically annotated from API 20E . |
| #68382 | Automatically annotated from API zym . |
| #69479 | João F Matias Rodrigues, Janko Tackmann,Gregor Rot, Thomas SB Schmidt, Lukas Malfertheiner, Mihai Danaila,Marija Dmitrijeva, Daniela Gaio, Nicolas Näpflin and Christian von Mering. University of Zurich.: MicrobeAtlas 1.0 beta . |
| #124043 | Isabel Schober, Julia Koblitz: Data extracted from sequence databases, automatically matched based on designation and taxonomy . |
| #125438 | Julia Koblitz, Lorenz Christian Reimer, Rüdiger Pukall, Jörg Overmann: Predicting bacterial phenotypic traits through improved machine learning using high-quality, curated datasets. 2024 ( DOI 10.1101/2024.08.12.607695 ) |
| #125439 | Philipp Münch, René Mreches, Martin Binder, Hüseyin Anil Gündüz, Xiao-Yin To, Alice McHardy: deepG: Deep Learning for Genome Sequence Data. R package version 0.3.1 . |
| #126262 | A. Lissin, I. Schober, J. F. Witte, H. Lüken, A. Podstawka, J. Koblitz, B. Bunk, P. Dawyndt, P. Vandamme, P. de Vos, J. Overmann, L. C. Reimer: StrainInfo—the central database for linked microbial strain identifiers. ( DOI 10.1093/database/baaf059 ) |
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