Methanobrevibacter ruminantium (DSM 1093, ATCC 35063, JCM 13430)

Name: Methanobrevibacter ruminantium (DSM 1093, ATCC 35063, JCM 13430)
Creator: BacDive
License: http://creativecommons.org/licenses/by/4.0/

BacDive ID 6962

Type strain

Strain Designation M1

Culture col. no. DSM 1093 ATCC 35063 JCM 13430 M1 OCM 146

NCBI tax ID(s) 634498 83816

Special Collections DSMZ JCM

History <- R. S. Wolfe, University of Illinois, Departments of Dairy Science and Microbiology, Urbana, USA; M1 <- M. P. Bryant; <- P. H. Smith and R. E. Hungate, University of California, Davis, USA; (Methanobacterium ruminantium) DSM 1093 <-- R. S. Wolfe <-- M. P. Bryant M1 <-- P. H. Smith and R. E. Hungate.

Links

Methanobrevibacter ruminantium M1 is an anaerobe, mesophilic prokaryote that was isolated from bovine rumen.

anaerobe mesophilic genome sequence 16S sequence

Name and taxonomic classification

SI-ID 40849

ATCC 35063,DSM 1093,JCM 13430

@ref 20215

Last LPSN update 2025-12-16 09:48:27

Domain Methanobacteriati

Phylum Methanobacteriota

Class Methanobacteria

Order Methanobacteriales

Family Methanobacteriaceae

Genus Methanobrevibacter

Species Methanobrevibacter ruminantium

Full scientific name Methanobrevibacter ruminantium (Smith and Hungate 1958) Balch and Wolfe 1981

Synonyms (1)

Methanobacterium ruminantium

Morphology

Cell morphology

@ref	Gram stain	Confidence
125439	negative	96.6

Culture and growth conditions

Culture medium

@ref	Name	Growth	Medium link	Composition
547	MODIFIED METHANOBACTERIUM MEDIUM (DSMZ Medium 1523)		Medium recipe at MediaDive	Name: MODIFIED METHANOBACTERIUM MEDIUM (DSMZ Medium 1523; with strain-specific modifications) Composition: Brain heart infusion 5.98802 g/l Proteose peptone 5.98802 g/l NaHCO3 3.99202 g/l Yeast extract 1.99601 g/l Na-formate 1.99601 g/l Na-acetate 0.998004 g/l 2-Mercaptoethanesulfonic acid 0.499002 g/l KH2PO4 0.499002 g/l Na2S x 9 H2O 0.499002 g/l L-Cysteine HCl x H2O 0.499002 g/l NH4Cl 0.399202 g/l NaCl 0.399202 g/l MgSO4 x 7 H2O 0.399202 g/l CaCl2 x 2 H2O 0.0499002 g/l HCl 0.00249501 g/l FeCl2 x 4 H2O 0.00149701 g/l Sodium resazurin 0.000499002 g/l Pyridoxine hydrochloride 0.000299401 g/l Nicotinic acid 0.000199601 g/l Thiamine-HCl x 2 H2O 0.000199601 g/l CoCl2 x 6 H2O 0.000189621 g/l Vitamin B12 9.98004e-05 g/l Calcium pantothenate 9.98004e-05 g/l MnCl2 x 4 H2O 9.98004e-05 g/l p-Aminobenzoic acid 7.98403e-05 g/l ZnCl2 6.98603e-05 g/l Na2MoO4 x 2 H2O 3.59281e-05 g/l NiCl2 x 6 H2O 2.39521e-05 g/l D-(+)-biotin 1.99601e-05 g/l H3BO3 5.98802e-06 g/l CuCl2 x 2 H2O 1.99601e-06 g/l Distilled water
547	METHANOBACTERIUM MEDIUM (DSMZ Medium 119)		Medium recipe at MediaDive	Name: METHANOBACTERIUM MEDIUM (DSMZ Medium 119) Composition: NaHCO3 3.98804 g/l Na-formate 1.99402 g/l Na-acetate 0.997009 g/l Na2S x 9 H2O 0.498504 g/l L-Cysteine HCl x H2O 0.498504 g/l KH2PO4 0.498504 g/l NH4Cl 0.398804 g/l NaCl 0.398804 g/l MgSO4 x 7 H2O 0.398804 g/l Yeast extract 0.199402 g/l CaCl2 x 2 H2O 0.0498504 g/l HCl 0.00249252 g/l FeSO4 x 7 H2O 0.00199402 g/l FeCl2 x 4 H2O 0.00149551 g/l Sodium resazurin 0.000498504 g/l CoCl2 x 6 H2O 0.000189432 g/l MnCl2 x 4 H2O 9.97009e-05 g/l ZnCl2 6.97906e-05 g/l Na2MoO4 x 2 H2O 3.58923e-05 g/l NiCl2 x 6 H2O 2.39282e-05 g/l H3BO3 5.98205e-06 g/l CuCl2 x 2 H2O 1.99402e-06 g/l Isobutyric acid DL-2-Methylbutyric acid Valeric acid Isovaleric acid H2SO4 Sludge Distilled water

Culture temp

@ref	Growth	Type	Temperature (°C)	Range
547	positive	growth	37	mesophilic
67770	positive	growth	37	mesophilic

Physiology and metabolism

Oxygen tolerance

@ref	Oxygen tolerance	Confidence
547	anaerobe
125438	anaerobe	90.448

Spore formation

@ref	Spore formation	Confidence
125439		99.2

Pathway annotation

Computationally determined by

@ref	pathway	enzyme coverage	annotated reactions
66794	ribulose monophosphate pathway	100	2 of 2
66794	anapleurotic synthesis of oxalacetate	100	1 of 1
66794	suberin monomers biosynthesis	100	2 of 2
66794	formaldehyde oxidation	100	3 of 3
66794	biotin biosynthesis	100	4 of 4
66794	UDP-GlcNAc biosynthesis	100	3 of 3
66794	coenzyme A metabolism	100	4 of 4
66794	flavin biosynthesis	93.33	14 of 15
66794	aspartate and asparagine metabolism	88.89	8 of 9
66794	chorismate metabolism	88.89	8 of 9
66794	molybdenum cofactor biosynthesis	88.89	8 of 9
66794	isoleucine metabolism	87.5	7 of 8
66794	phenylalanine metabolism	84.62	11 of 13
66794	NAD metabolism	83.33	15 of 18
66794	hydrogen production	80	4 of 5
66794	factor 420 biosynthesis	80	4 of 5
66794	methanofuran biosynthesis	80	4 of 5
66794	vitamin B12 metabolism	79.41	27 of 34
66794	valine metabolism	77.78	7 of 9
66794	palmitate biosynthesis	77.27	17 of 22
66794	acetate fermentation	75	3 of 4
66794	methanogenesis from CO2	75	9 of 12
66794	6-hydroxymethyl-dihydropterin diphosphate biosynthesis	75	6 of 8
66794	sulfopterin metabolism	75	3 of 4
66794	ubiquinone biosynthesis	71.43	5 of 7
66794	pyrimidine metabolism	71.11	32 of 45
66794	coenzyme M biosynthesis	70	7 of 10
66794	threonine metabolism	70	7 of 10
66794	vitamin B1 metabolism	69.23	9 of 13
66794	glutamate and glutamine metabolism	67.86	19 of 28
66794	purine metabolism	67.02	63 of 94
66794	pantothenate biosynthesis	66.67	4 of 6
66794	CO2 fixation in Crenarchaeota	66.67	6 of 9
66794	L-lactaldehyde degradation	66.67	2 of 3
66794	acetoin degradation	66.67	2 of 3
66794	selenocysteine biosynthesis	66.67	4 of 6
66794	photosynthesis	64.29	9 of 14
66794	heme metabolism	64.29	9 of 14
66794	C4 and CAM-carbon fixation	62.5	5 of 8
66794	methionine metabolism	61.54	16 of 26
66794	lipid metabolism	61.29	19 of 31
66794	myo-inositol biosynthesis	60	6 of 10
66794	peptidoglycan biosynthesis	60	9 of 15
66794	citric acid cycle	57.14	8 of 14
66794	d-mannose degradation	55.56	5 of 9
66794	nitrate assimilation	55.56	5 of 9
66794	oxidative phosphorylation	53.85	49 of 91
66794	glycolysis	52.94	9 of 17
66794	histidine metabolism	51.72	15 of 29
66794	vitamin E metabolism	50	2 of 4
66794	propionate fermentation	50	5 of 10
66794	cis-vaccenate biosynthesis	50	1 of 2
66794	dolichol and dolichyl phosphate biosynthesis	50	1 of 2
66794	gluconeogenesis	50	4 of 8
66794	glycolate and glyoxylate degradation	50	3 of 6
66794	aminopropanol phosphate biosynthesis	50	1 of 2
66794	ethanol fermentation	50	1 of 2
66794	glycine metabolism	50	5 of 10
66794	dTDPLrhamnose biosynthesis	50	4 of 8
66794	glycogen biosynthesis	50	2 of 4
66794	butanoate fermentation	50	2 of 4
66794	arginine metabolism	50	12 of 24
66794	cysteine metabolism	50	9 of 18
66794	adipate degradation	50	1 of 2
66794	tyrosine metabolism	50	7 of 14
66794	CDP-diacylglycerol biosynthesis	50	1 of 2
66794	non-pathway related	47.37	18 of 38
66794	leucine metabolism	46.15	6 of 13
66794	proline metabolism	45.45	5 of 11
66794	tryptophan metabolism	44.74	17 of 38
66794	serine metabolism	44.44	4 of 9
66794	degradation of sugar alcohols	43.75	7 of 16
66794	reductive acetyl coenzyme A pathway	42.86	3 of 7
66794	tetrahydrofolate metabolism	42.86	6 of 14
66794	cardiolipin biosynthesis	42.86	3 of 7
66794	aclacinomycin biosynthesis	42.86	3 of 7
66794	propanol degradation	42.86	3 of 7
66794	degradation of aromatic, nitrogen containing compounds	41.67	5 of 12
66794	alanine metabolism	41.38	12 of 29
66794	4-hydroxyphenylacetate degradation	40	4 of 10
66794	metabolism of amino sugars and derivatives	40	2 of 5
66794	urea cycle	38.46	5 of 13
66794	isoprenoid biosynthesis	38.46	10 of 26
66794	lysine metabolism	38.1	16 of 42
66794	ketogluconate metabolism	37.5	3 of 8
66794	dolichyl-diphosphooligosaccharide biosynthesis	36.36	4 of 11
66794	pentose phosphate pathway	36.36	4 of 11
66794	vitamin B6 metabolism	36.36	4 of 11
66794	IAA biosynthesis	33.33	1 of 3
66794	methane metabolism	33.33	1 of 3
66794	cyanate degradation	33.33	1 of 3
66794	acetyl CoA biosynthesis	33.33	1 of 3
66794	octane oxidation	33.33	1 of 3
66794	degradation of hexoses	33.33	6 of 18
66794	lipid A biosynthesis	33.33	3 of 9
66794	sulfate reduction	30.77	4 of 13
66794	polyamine pathway	30.43	7 of 23
66794	degradation of pentoses	28.57	8 of 28
66794	benzoyl-CoA degradation	28.57	2 of 7
66794	mevalonate metabolism	28.57	2 of 7
66794	glutathione metabolism	28.57	4 of 14
66794	lactate fermentation	25	1 of 4
66794	cyclohexanol degradation	25	1 of 4
66794	toluene degradation	25	1 of 4
66794	catecholamine biosynthesis	25	1 of 4
66794	CMP-KDO biosynthesis	25	1 of 4
66794	phenylpropanoid biosynthesis	23.08	3 of 13
66794	phosphatidylethanolamine bioynthesis	23.08	3 of 13
66794	ascorbate metabolism	22.73	5 of 22
66794	allantoin degradation	22.22	2 of 9

Isolation, sampling and environmental information

Isolation source categories

Cat1	Cat2	Cat3
#Host	#Mammals	#Bovinae (Cow, Cattle)
#Host Body-Site	#Organ	#Rumen

Isolation

547

Sample typebovine rumen

Taxonmaps

69479

Global distribution of 16S sequence AY196666 (>99% sequence identity) for Methanobrevibacter ruminantium subclade from Microbeatlas

Aquatic Samples	14
Soil Samples	46
Animal Samples	1166
Plant Samples	122
Total Samples	1348

Interaction and safety

Risk assessment

@ref	Biosafety level	Biosafety level comment
547	1	Risk group (German classification) According to TRBA 466

Sequence information

Genome sequences

@ref	Description	Assembly level	INSDC accession	BV-BRC accession	IMG accession	NCBI tax ID	Score
66792	ASM2418v1 assembly for Methanobrevibacter ruminantium M1	complete	GCA_000024185	634498.28	646311943	634498	99.02

16S sequences

@ref	Description	Accession	Length	Database	NCBI tax ID
67770	Methanobrevibacter ruminantium 16S ribosomal RNA gene, partial sequence	AY196666	1260		634498

GC content

@ref	GC-content (mol%)	Method
547	30.6
547	32.6	sequence analysis

Genome-based predictions

Predictions

Predictions from Deep Learning for Genome Sequence Data. R package version 0.3.1 based on: Methanobrevibacter ruminantium M1
NCBI: GCA_000024185

@ref	Trait	Model	Prediction	Confidence in %	In training data
125439	spore_formation	BacteriaNetⓘ	no	99.20	no
125439	motility	BacteriaNetⓘ	no	71.70	no
125439	gram_stain	BacteriaNetⓘ	negative	96.60	no
125439	oxygen_tolerance	BacteriaNetⓘ	obligate anaerobe	75.50	no

Predictions from bacterial phenotypic traits through improved machine learning using high-quality, curated datasets based on: Methanobrevibacter ruminantium M1 M1
NCBI: GCA_000024185.1

@ref	Trait	Model	Prediction	Confidence in %	In training data
125438	gram-positive	gram-positiveⓘ	no	60.07	no
125438	anaerobic	anaerobicⓘ	yes	90.45	yes
125438	aerobic	aerobicⓘ	no	91.37	yes
125438	spore-forming	spore-formingⓘ	no	89.20	no
125438	thermophilic	thermophileⓘ	no	80.71	yes
125438	flagellated	motile2+ⓘ	no	82.71	no

Literature

Topic	Title	Authors	Journal	DOI	Year
Metabolism	Rumen microbial degradation of bromoform from red seaweed (Asparagopsis taxiformis) and the impact on rumen fermentation and methanogenic archaea.	Romero P, Belanche A, Jimenez E, Hueso R, Ramos-Morales E, Salwen JK, Kebreab E, Yanez-Ruiz DR.	J Anim Sci Biotechnol	10.1186/s40104-023-00935-z	2023
	Rumen microbiota associated with feed efficiency in beef cattle are highly influenced by diet composition.	Ortiz-Chura A, Corral-Jara KF, Tournayre J, Cantalapiedra-Hijar G, Popova M, Morgavi DP.	Anim Nutr	10.1016/j.aninu.2024.11.027	2025
Phylogeny	Genome reduction in novel, obligately methyl-reducing Methanosarcinales isolated from arthropod guts (Methanolapillus gen. nov. and Methanimicrococcus).	Protasov E, Reeh H, Liu P, Poehlein A, Platt K, Heimerl T, Herve V, Daniel R, Brune A.	FEMS Microbiol Ecol	10.1093/femsec/fiae111	2024
	Cross-reactivity of antibodies to different rumen methanogens demonstrated using immunomagnetic capture technology.	Khanum S, Roberts JM, Heathcott RW, Bagley S, Wilson T, Gupta SK, Kirk MR, Heiser A, Janssen PH, Wedlock DN.	Front Microbiol	10.3389/fmicb.2022.918111	2022
Biotechnology	Tailored Nanoparticles With the Potential to Reduce Ruminant Methane Emissions.	Altermann E, Reilly K, Young W, Ronimus RS, Muetzel S.	Front Microbiol	10.3389/fmicb.2022.816695	2022
	Inhibition of Rumen Methanogens by a Novel Archaeal Lytic Enzyme Displayed on Tailored Bionanoparticles.	Altermann E, Schofield LR, Ronimus RS, Beatty AK, Reilly K.	Front Microbiol	10.3389/fmicb.2018.02378	2018
	Evolving understanding of rumen methanogen ecophysiology.	Khairunisa BH, Heryakusuma C, Ike K, Mukhopadhyay B, Susanti D.	Front Microbiol	10.3389/fmicb.2023.1296008	2023
	Enteric methane emission of dairy cows supplemented with iodoform in a dose-response study.	Thorsteinsson M, Lund P, Weisbjerg MR, Noel SJ, Schonherz AA, Hellwing ALF, Hansen HH, Nielsen MO.	Sci Rep	10.1038/s41598-023-38149-y	2023
Metabolism	Expression, Purification, and Characterization of (R)-Sulfolactate Dehydrogenase (ComC) from the Rumen Methanogen Methanobrevibacter millerae SM9.	Zhang Y, Schofield LR, Sang C, Dey D, Ronimus RS.	Archaea	10.1155/2017/5793620	2017
	Methane Production in Dairy Cows Correlates with Rumen Methanogenic and Bacterial Community Structure.	Danielsson R, Dicksved J, Sun L, Gonda H, Muller B, Schnurer A, Bertilsson J.	Front Microbiol	10.3389/fmicb.2017.00226	2017
Metabolism	Hydrogenotrophic methanogens of the mammalian gut: Functionally similar, thermodynamically different-A modelling approach.	Munoz-Tamayo R, Popova M, Tillier M, Morgavi DP, Morel JP, Fonty G, Morel-Desrosiers N.	PLoS One	10.1371/journal.pone.0226243	2019
	Benefits and Challenges of Jatropha Meal as Novel Biofeed for Animal Production.	Oskoueian E, Oskoueian A, Shakeri M, Jahromi MF.	Vet Sci	10.3390/vetsci8090179	2021
Metabolism	Early life dietary intervention in dairy calves results in a long-term reduction in methane emissions.	Meale SJ, Popova M, Saro C, Martin C, Bernard A, Lagree M, Yanez-Ruiz DR, Boudra H, Duval S, Morgavi DP.	Sci Rep	10.1038/s41598-021-82084-9	2021
	The Structural and Functional Capacity of Ruminal and Cecal Microbiota in Growing Cattle Was Unaffected by Dietary Supplementation of Linseed Oil and Nitrate.	Popova M, McGovern E, McCabe MS, Martin C, Doreau M, Arbre M, Meale SJ, Morgavi DP, Waters SM.	Front Microbiol	10.3389/fmicb.2017.00937	2017
Metabolism	A1Ao-ATP synthase of Methanobrevibacter ruminantium couples sodium ions for ATP synthesis under physiological conditions.	McMillan DG, Ferguson SA, Dey D, Schroder K, Aung HL, Carbone V, Attwood GT, Ronimus RS, Meier T, Janssen PH, Cook GM.	J Biol Chem	10.1074/jbc.m111.281675	2011
Metabolism	Biochemical Characterisation of Phage Pseudomurein Endoisopeptidases PeiW and PeiP Using Synthetic Peptides.	Schofield LR, Beattie AK, Tootill CM, Dey D, Ronimus RS.	Archaea	10.1155/2015/828693	2015
Metabolism	The genome sequence of the rumen methanogen Methanobrevibacter ruminantium reveals new possibilities for controlling ruminant methane emissions.	Leahy SC, Kelly WJ, Altermann E, Ronimus RS, Yeoman CJ, Pacheco DM, Li D, Kong Z, McTavish S, Sang C, Lambie SC, Janssen PH, Dey D, Attwood GT.	PLoS One	10.1371/journal.pone.0008926	2010
Phylogeny	Sequence, structure and functional diversity of PD-(D/E)XK phosphodiesterase superfamily.	Steczkiewicz K, Muszewska A, Knizewski L, Rychlewski L, Ginalski K.	Nucleic Acids Res	10.1093/nar/gks382	2012
Phylogeny	An antimethanogenic nutritional intervention in early life of ruminants modifies ruminal colonization by Archaea.	Abecia L, Waddams KE, Martinez-Fernandez G, Martin-Garcia AI, Ramos-Morales E, Newbold CJ, Yanez-Ruiz DR.	Archaea	10.1155/2014/841463	2014
Phylogeny	Methanogens and methanogenesis in the rumens and ceca of lambs fed two different high-grain-content diets.	Popova M, Morgavi DP, Martin C.	Appl Environ Microbiol	10.1128/aem.03115-12	2013
Phylogeny	Methanogens: reevaluation of a unique biological group.	Balch WE, Fox GE, Magrum LJ, Woese CR, Wolfe RS.	Microbiol Rev	10.1128/mr.43.2.260-296.1979	1979
Phylogeny	Phylogenetic analysis of methanogens from the bovine rumen.	Whitford MF, Teather RM, Forster RJ.	BMC Microbiol	10.1186/1471-2180-1-5	2001
	Genome-resolved metagenomics and metatranscriptomics reveal niche differentiation in functionally redundant microbial communities at deep-sea hydrothermal vents.	Galambos D, Anderson RE, Reveillaud J, Huber JA.	Environ Microbiol	10.1111/1462-2920.14806	2019
	Characterization of the cecum microbiome from wild and captive rock ptarmigans indigenous to Arctic Norway.	Salgado-Flores A, Tveit AT, Wright AD, Pope PB, Sundset MA.	PLoS One	10.1371/journal.pone.0213503	2019
	Investigating the antimethanogenic effects of selected nitro-compounds on methane production, rumen fermentation, and methanogenic archaea in vitro.	Castaneda A, Indugu N, Challa K, Narayan K, Johnson A, Stefanovski D, Webb T, Zhao X, Pitta D.	Appl Environ Microbiol	10.1128/aem.01033-25	2025
Phenotype	Effects of methane inhibitors on ruminal fermentation and microbial composition in vitro using inoculum from phenotypically high- and low-enteric-methane-emitting cows.	Stepanchenko N, Wasson DE, Indugu N, Cueva SF, Martins L, Narayan K, Pitta DW, Hristov AN.	J Dairy Sci	10.3168/jds.2025-26408	2025
	Differential alteration of rumen microbial composition in response to 3-nitrooxypropanol supplementation in dairy cattle fed high-grain and high-forage diets.	Choi Y, Zhou M, Ban Y, Oba M, Duval S, Guan LL.	J Dairy Sci	10.3168/jds.2024-26206	2025
	Effects of dietary supplementation of nitrate on enteric methane production, performance, and rumen microbiome of Hanwoo steers.	Bharanidharan R, Tomple BM, Lee J, Nirmal Athauda AAK, Huh S, Hong W, Kim NY, Lim DH, Kim JG, Kim KH, Oh J.	J Anim Sci	10.1093/jas/skaf109	2025
	Evaluating the rumen microbial community of genetically divergent spring-calving dairy cows grazing grass-only or grass-clover swards at different stages of the grazing season.	Dwan C, Das A, O'Toole PW, O'Callaghan TF, Meehan D, Hennessy D, Irish H, Buckley F, Lahart B.	Front Microbiol	10.3389/fmicb.2025.1642486	2025
	Development and characterisation of brown seaweed hydrolysates and fermentates with potential to reduce enteric methane.	De Bhowmick G, Rai DK, Olatunji O, Kilcawley K, Skibinska I, Shannon E, Kennedy D, Walsh D, Mora L, Hayes M.	Sci Rep	10.1038/s41598-025-05387-1	2025
	Microbiome-informed study of the mechanistic basis of methane inhibition by Asparagopsis taxiformis in dairy cattle.	Indugu N, Narayan K, Stefenoni HA, Hennessy ML, Vecchiarelli B, Bender JS, Shah R, Dai G, Garapati S, Yarish C, Welchez SC, Raisanen SE, Wasson D, Lage C, Melgar A, Hristov AN, Pitta DW.	mBio	10.1128/mbio.00782-24	2024
	Microbial diurnal rhythmicity in the rumen fluid impacted by feeding regimes and exogenous microbiome providing novel mechanisms regulating dynamics of the rumen microbiome.	Hao Y, Wang W, Li M, Choi Y, Zhou M, Wang Y, Cao Z, Wang YJ, Yang H, Jiang L, Guan LL, Li S.	Microbiome	10.1186/s40168-025-02134-6	2025
	Rumen acidosis in ruminants: a review of the effects of high-concentrate diets and the potential modulatory role of rumen foam.	Mao J, Wang L.	Front Vet Sci	10.3389/fvets.2025.1595615	2025
	Programming rumen microbiome development in calves with the anti-methanogenic compound 3-NOP.	Martinez-Fernandez G, Denman SE, Walker N, Kindermann M, McSweeney CS.	Anim Microbiome	10.1186/s42523-024-00343-2	2024
	Bacterial species in the ruminal content of steers fed oilseeds in the diet.	de Melo HSA, Itavo LCV, de Castro AP, Itavo CCBF, de Araujo Caldas R, Mateus RG, Niwa MVG, de Moraes GJ, da Silva Zornitta C, Gurgel ALC, Benchaar C.	Trop Anim Health Prod	10.1007/s11250-022-03399-x	2022
Phenotype	Host-specific microbiome-rumination interactions shape methane-yield phenotypes in dairy cattle.	Castaneda A, Indugu N, Lenker K, Narayan K, Rassler S, Bender J, Baker L, Purandare O, Chai D, Zhao X, Pitta D.	mSphere	10.1128/msphere.00090-25	2025
	Metagenomic Comparison of Gut Microbes of Lemur catta in Captive and Semi-Free-Range Environments.	Xu C, Guo X, Li L.	Animals (Basel)	10.3390/ani15101442	2025
Phylogeny	Effects of Dietary Nonfibrous Carbohydrate/Neutral Detergent Fiber Ratio on Methanogenic Archaea and Cellulose-Degrading Bacteria in the Rumen of Karakul Sheep: a 16S rRNA Gene Sequencing Study.	Bai T, Pu X, Guo X, Liu J, Zhao L, Zhang X, Zhang S, Cheng L.	Appl Environ Microbiol	10.1128/aem.01291-22	2023
Transcriptome	Enhanced propionate and butyrate metabolism in cecal microbiota contributes to cold-stress adaptation in sheep.	Cheng X, Liang Y, Ji K, Feng M, Du X, Jiao D, Wu X, Zhong C, Cong H, Yang G.	Microbiome	10.1186/s40168-025-02096-9	2025
	Temporal changes in total and metabolically active ruminal methanogens in dairy cows supplemented with 3-nitrooxypropanol.	Pitta DW, Melgar A, Hristov AN, Indugu N, Narayan KS, Pappalardo C, Hennessy ML, Vecchiarelli B, Kaplan-Shabtai V, Kindermann M, Walker N.	J Dairy Sci	10.3168/jds.2020-19862	2021
Enzymology	Biophysical and biochemical characterization of a thermostable archaeal cyclophilin from Methanobrevibacter ruminantium.	Kaushik V, Prasad S, Goel M.	Int J Biol Macromol	10.1016/j.ijbiomac.2019.07.149	2019
Pathogenicity	Moderate altitude exposure impacts extensive host-microbiota multi-kingdom connectivity with serum metabolome and fasting blood glucose.	Huang X, Gao X, Fan Y, Wang D, Chen X, Qi X, Yang Z, Wang YE, Meng J, Zou G, Liu Z, Li X.	Virulence	10.1080/21505594.2025.2530660	2025
	Supplementation with avian-derived polyclonal antibodies against Methanobrevibacter gottschalkii and M. ruminantium decreases ex vivo methane production and modifies ruminal fermentation in Angus crossbred steers.	Garcia-Ascolani ME, Tarnonsky F, Roskopf S, Podversich F, Silva GM, Schulmeister TM, Ruiz-Moreno M, Hackmann TJ, Dubeux JCB, DiLorenzo N.	J Anim Sci	10.1093/jas/skae213	2024
	Effect of silkworm (Bombyx mori) pupae oil supplementation on enteric methane emission and methanogens diversity in sheep.	Thirumalaisamy G, Malik PK, Kolte AP, Trivedi S, Dhali A, Bhatta R.	Anim Biotechnol	10.1080/10495398.2020.1781147	2022
	Effects of cofD gene knock-out on the methanogenesis of Methanobrevibacter ruminantium.	Ma J, Wang X, Zhou T, Hu R, Zou H, Wang Z, Tan C, Zhang X, Peng Q, Xue B, Wang L.	AMB Express	10.1186/s13568-021-01236-2	2021
	Degradability, rumen fermentation, and rumen microbiota of livestock rations containing different levels of Azolla pinnata.	Abd-Elgwad AFA, Bakr SA, Sabra EA, Elwakeel EA, Khorshed MM, Metwally HM, Rabee AE.	AIMS Microbiol	10.3934/microbiol.2025028	2025
Pathogenicity	The crosstalk between host and rumen microbiome in cattle: insights from multi-omics approaches and genome-wide association studies.	Ye X, Sahana G, Lund MS, Cai Z.	World J Microbiol Biotechnol	10.1007/s11274-025-04504-6	2025
	Enhancing the Conventional Culture: the Evaluation of Several Culture Media and Growth Conditions Improves the Isolation of Ruminal Bacteria.	Botero Rute LM, Caro-Quintero A, Acosta-Gonzalez A.	Microb Ecol	10.1007/s00248-023-02319-2	2023
	Sex-Induced Changes in Microbial Eukaryotes and Prokaryotes in Gastrointestinal Tract of Simmental Cattle.	Rojas D, Estrada R, Romero Y, Figueroa D, Quilcate C, Ganoza-Roncal JJ, Maicelo JL, Coila P, Alvarado W, Cayo-Colca IS.	Biology (Basel)	10.3390/biology13110932	2024
	Relationship between jejunum ATPase activity and antioxidant function on the growth performance, feed conversion efficiency, and jejunum microbiota in Hu sheep (Ovis aries).	Chen Z, Wang G, Wang W, Wang X, Huang Y, Jia J, Gao Q, Xu H, He L, Xu Y, Liu Z, Sun J, Li C.	BMC Vet Res	10.1186/s12917-024-04100-0	2024
	Unlocking gut microbiota potential of dairy cows in varied environmental conditions using shotgun metagenomic approach.	Khan FA, Pandupuspitasari NS, Huang C, Negara W, Ahmed B, Putri EM, Lestari P, Priyatno TP, Prima A, Restitrisnani V, Surachman M, Akhadiarto S, Darmawan IWA, Wahyuni DS, Herdis H.	BMC Microbiol	10.1186/s12866-023-03101-7	2023
Metabolism	Methane Emission, Rumen Fermentation, and Microbial Community Response to a Nitrooxy Compound in Low-Quality Forage Fed Hu Sheep.	Xie F, Zhang L, Jin W, Meng Z, Cheng Y, Wang J, Zhu W.	Curr Microbiol	10.1007/s00284-019-01644-5	2019
	Characterization of the ruminal microbiota in sheep and goats fed different levels of tannin-rich Sericea lespedeza hay.	Min BR, Wang W, Pitta DW, Indugu N, Patra AK, Wang HH, Abrahamsen F, Hilaire M, Puchala R.	J Anim Sci	10.1093/jas/skae198	2024
	Weaning Time Affects the Archaeal Community Structure and Functional Potential in Pigs.	Deng F, Peng Y, Zhang Z, Howe S, Wu Z, Dou J, Li Y, Wei X, Wang X, Liang Y, Zhao J, Li Y.	Front Microbiol	10.3389/fmicb.2022.845621	2022
Genetics	Metagenomics reveals differences in microbial composition and metabolic functions in the rumen of dairy cows with different residual feed intake.	Xie Y, Sun H, Xue M, Liu J.	Anim Microbiome	10.1186/s42523-022-00170-3	2022
Pathogenicity	Effects of feeding mycotoxin-contaminated diets and the use of a yeast cell wall extracts mycotoxin adsorbent on ruminal and fecal microbiota of finishing beef steers.	Batista LHC, Granja-Salcedo YT, Ferreira IM, de Souza MG, de Abreu MJI, Costa E Silva LF, Koontz A, Holder V, Pettigrew JE, Siqueira GR, de Resende FD.	Front Microbiol	10.3389/fmicb.2025.1675653	2025
	Roughage biodegradation by natural co-cultures of rumen fungi and methanogens from Qinghai yaks.	Wei Y, Yang H, Wang Z, Zhao J, Qi H, Wang C, Zhang J, Yang T.	AMB Express	10.1186/s13568-022-01462-2	2022
	Effects of dairy cow diets supplied with flaxseed oil and propolis extract, with or without vitamin E, on the ruminal microbiota, biohydrogenation, and digestion	Yoshimura EH, Santos NW, Machado E, Agustinho BC, Pereira LM, de Aguiar SC, Franzolin R, Gasparino E, dos Santos GT, Zeoula LM.	Anim Feed Sci Technol	10.1016/j.anifeedsci.2018.04.024	2018
	Exploring the impact of forage-to-concentrate ratios on the ruminal bacteriome in vitro focusing on ciliate-associated bacteria.	Kim G, Lee W, Park T.	Sci Rep	10.1038/s41598-025-10599-6	2025
	Composition of the rumen archaeal community of growing camels fed different concentrate levels.	Rabee AE, Askar AR.	Int Microbiol	10.1007/s10123-023-00459-6	2025
	Screening macroalgae for mitigation of enteric methane in vitro.	Wasson DE, Stefenoni H, Cueva SF, Lage C, Raisanen SE, Melgar A, Fetter M, Hennessy M, Narayan K, Indugu N, Pitta D, Yarish C, Hristov AN.	Sci Rep	10.1038/s41598-023-36359-y	2023
	- Invited Review - Understanding the functionality of the rumen microbiota: searching for better opportunities for rumen microbial manipulation.	Qi W, Xue MY, Jia MH, Zhang S, Yan Q, Sun HZ.	Anim Biosci	10.5713/ab.23.0308	2024
	Feed Intake, Methane Emissions, Milk Production and Rumen Methanogen Populations of Grazing Dairy Cows Supplemented with Various C 18 Fatty Acid Sources.	Boland TM, Pierce KM, Kelly AK, Kenny DA, Lynch MB, Waters SM, Whelan SJ, McKay ZC.	Animals (Basel)	10.3390/ani10122380	2020
Phylogeny	Sequencing and culture-based characterization of the vaginal and uterine microbiota in beef cattle that became pregnant or remained open following artificial insemination.	Webb EM, Holman DB, Schmidt KN, Pun B, Sedivec KK, Hurlbert JL, Bochantin KA, Ward AK, Dahlen CR, Amat S.	Microbiol Spectr	10.1128/spectrum.02732-23	2023
Metabolism	Fiber degradation potential of natural co-cultures of Neocallimastix frontalis and Methanobrevibacter ruminantium isolated from yaks (Bos grunniens) grazing on the Qinghai Tibetan Plateau.	Wei YQ, Long RJ, Yang H, Yang HJ, Shen XH, Shi RF, Wang ZY, Du JG, Qi XJ, Ye QH.	Anaerobe	10.1016/j.anaerobe.2016.03.005	2016
	Characterization of Cyclophilin from Thaumarchaeota Nitrosopumilus maritimus: Implications on the Diversity of Chaperone-like Activity in the Archaeal Domain.	Kaushik V, Anchal, Goel M.	ACS Omega	10.1021/acsomega.1c03216	2022
	Diversity of rumen microbiota using metagenome sequencing and methane yield in Indian sheep fed on straw and concentrate diet.	Malik PK, Trivedi S, Kolte AP, Sejian V, Bhatta R, Rahman H.	Saudi J Biol Sci	10.1016/j.sjbs.2022.103345	2022
Genetics	Seasonal stability of the rumen microbiome contributes to the adaptation patterns to extreme environmental conditions in grazing yak and cattle.	Guo W, Zhou M, Li F, Neves ALA, Ma T, Bi S, Wang W, Long R, Guan LL.	BMC Biol	10.1186/s12915-024-02035-4	2024
Phylogeny	Establishment of methanogen bacterial interactions during the preweaning period of dairy cattle.	Indugu N, Narayan KS, Hennessy ML, Pitta D.	PLoS One	10.1371/journal.pone.0310648	2024
	Effect of Dietary Supplementation of Moringa Oleifera on the Production Performance and Fecal Methanogenic Community of Lactating Dairy Cows.	Dong L, Zhang T, Diao Q.	Animals (Basel)	10.3390/ani9050262	2019
	Computational Network Inference for Bacterial Interactomics.	James K, Munoz-Munoz J.	mSystems	10.1128/msystems.01456-21	2022
Genetics	Multiomics of yaks reveals significant contribution of microbiome into host metabolism.	Yang S, Zheng J, Mao H, Vinitchaikul P, Wu D, Chai J.	NPJ Biofilms Microbiomes	10.1038/s41522-024-00609-2	2024
	Effects of Thymol Supplementation on Goat Rumen Fermentation and Rumen Microbiota In Vitro.	Yu J, Cai L, Zhang J, Yang A, Wang Y, Zhang L, Guan LL, Qi D.	Microorganisms	10.3390/microorganisms8081160	2020
Phylogeny	Specific gastrointestinal microbiota profiles in Chinese Tan sheep are associated with lauric acid content in muscle.	Li Z, Cui R, Wang YB, Luo YB, Xue PX, Tang QG, Fang MY.	BMC Microbiol	10.1186/s12866-023-03079-2	2023
	Interactive Web-Based Tool for Nutritional Microbiology in Applied Agriculture Outreach.	Zambito Ivey JL, Myer PR.	J Microbiol Biol Educ	10.1128/jmbe.v19i2.1557	2018
Enzymology	The crystal structure of methenyltetrahydromethanopterin cyclohydrolase from Methanobrevibacter ruminantium.	Carbone V, Schofield LR, Beattie AK, Sutherland-Smith AJ, Ronimus RS.	Proteins	10.1002/prot.24372	2013
	Structural and functional insights from the sequences and complex domain architecture of adhesin-like proteins from Methanobrevibacter smithii and Methanosphaera stadtmanae.	Gupta AB, Seedorf H.	Front Microbiol	10.3389/fmicb.2024.1463715	2024
Enzymology	The effect of dietary Chlorella vulgaris supplementation on micro-organism community, enzyme activities and fatty acid profile in the rumen liquid of goats.	Tsiplakou E, Abdullah MA, Skliros D, Chatzikonstantinou M, Flemetakis E, Labrou N, Zervas G.	J Anim Physiol Anim Nutr (Berl)	10.1111/jpn.12521	2017
Pathogenicity	Effects of long-acting, broad spectra anthelmintic treatments on the rumen microbial community compositions of grazing sheep.	Moon CD, Carvalho L, Kirk MR, McCulloch AF, Kittelmann S, Young W, Janssen PH, Leathwick DM.	Sci Rep	10.1038/s41598-021-82815-y	2021
Pathogenicity	Effect of dietary fiber on the methanogen community in the hindgut of Lantang gilts.	Cao Z, Liang JB, Liao XD, Wright AD, Wu YB, Yu B.	Animal	10.1017/s1751731116000525	2016
	Accessing Dietary Effects on the Rumen Microbiome: Different Sequencing Methods Tell Different Stories.	Zhou M, O'Hara E, Tang S, Chen Y, Walpole ME, Gorka P, Penner GB, Guan LL.	Vet Sci	10.3390/vetsci8070138	2021
Phylogeny	Characterization of the Rumen Microbiota and Volatile Fatty Acid Profiles of Weaned Goat Kids under Shrub-Grassland Grazing and Indoor Feeding.	Guo J, Li P, Liu S, Miao B, Zeng B, Jiang Y, Li L, Wang L, Chen Y, Zhang H.	Animals (Basel)	10.3390/ani10020176	2020
Metabolism	Isolation, identification and fibrolytic characteristics of rumen fungi grown with indigenous methanogen from yaks (Bos grunniens) grazing on the Qinghai-Tibetan Plateau.	Wei YQ, Yang HJ, Luan Y, Long RJ, Wu YJ, Wang ZY.	J Appl Microbiol	10.1111/jam.13035	2016
Genetics	Effects of Short-Chain Fatty Acid Modulation on Potentially Diarrhea-Causing Pathogens in Yaks Through Metagenomic Sequencing.	Li K, Zeng Z, Liu J, Pei L, Wang Y, Li A, Kulyar MF, Shahzad M, Mehmood K, Li J, Qi D.	Front Cell Infect Microbiol	10.3389/fcimb.2022.805481	2022
	Annotating functional RNAs in genomes using Infernal.	Nawrocki EP.	Methods Mol Biol	10.1007/978-1-62703-709-9_9	2014
Phylogeny	Contrasting Fecal Methanogenic and Bacterial Profiles of Organic Dairy Cows Located in Northwest Washington Receiving Either a Mixed Diet of Pasture and TMR or Solely TMR.	Slanzon G, Sischo W, McConnel C.	Animals (Basel)	10.3390/ani12202771	2022
Genetics	Perspectives of gene editing for cattle farming in tropical and subtropical regions.	Camargo LSA, Saraiva NZ, Oliveira CS, Carmickle A, Lemos DR, Siqueira LGB, Denicol AC.	Anim Reprod	10.1590/1984-3143-ar2022-0108	2022
	Understanding the sources, function, and irreplaceable role of cobamides in organohalide-respiring bacteria.	Lu Y, Lu F, Zhang J, Tang Q, Yang D, Liu Y.	Front Microbiol	10.3389/fmicb.2024.1435674	2024
Metabolism	Navigating the archaeal frontier: insights and projections from bioinformatic pipelines.	Karavaeva V, Sousa FL.	Front Microbiol	10.3389/fmicb.2024.1433224	2024
	Survey of rumen microbiota of domestic grazing yak during different growth stages revealed novel maturation patterns of four key microbial groups and their dynamic interactions.	Guo W, Zhou M, Ma T, Bi S, Wang W, Zhang Y, Huang X, Guan LL, Long R.	Anim Microbiome	10.1186/s42523-020-00042-8	2020
Phylogeny	Methanogenic archaea diversity in Hanwoo (Bos taurus coreanae) rumen fluid, rectal dung, and barn floor manure using a culture-independent method based on mcrA gene sequences.	Daquiado AR, Cho KM, Kim TY, Kim SC, Chang HH, Lee YB.	Anaerobe	10.1016/j.anaerobe.2014.01.008	2014
	Effects of Starch Level and a Mixture of Sunflower and Fish Oils on Nutrient Intake and Digestibility, Rumen Fermentation, and Ruminal Methane Emissions in Dairy Cows.	Darabighane B, Tapio I, Ventto L, Kairenius P, Stefanski T, Leskinen H, Shingfield KJ, Vilkki J, Bayat AR.	Animals (Basel)	10.3390/ani11051310	2021
Pathogenicity	Archaeal virus entry and egress.	Kuiper BP, Schontag AMC, Oksanen HM, Daum B, Quax TEF.	Microlife	10.1093/femsml/uqad048	2024
Enzymology	Technical note: Comparison of biomarker and molecular biological methods for estimating methanogen abundance.	McCartney CA, Bull ID, Waters SM, Dewhurst RJ.	J Anim Sci	10.2527/jas.2013-6513	2013
Genetics	Virome and metagenomic analysis reveal the distinct distribution of microbiota in human fetal gut during gestation.	Liu X, He G, Lan Y, Guo W, Liu X, Li J, Liu A, He M, Liu X, Fan Z, Zhang Y.	Front Immunol	10.3389/fimmu.2022.1079294	2022
	Effects of propyl propane thiosulfinate on nutrient utilization, ruminal fermentation, microbial population and methane emissions in goats	Martinez-Fernandez G, Abecia L, Ramos-Morales E, Martin-Garcia AI, Molina-Alcaide E, Yanez-Ruiz DR.	Anim Feed Sci Technol	10.1016/j.anifeedsci.2014.01.008	2014
Genetics	Rumen metagenome reveals the mechanism of mitigation methane emissions by unsaturated fatty acid while maintaining the performance of dairy cows.	Yang Z, Zheng Y, Liu S, Xie T, Wang Q, Wang Z, Li S, Wang W.	Anim Nutr	10.1016/j.aninu.2024.06.003	2024
Metabolism	Differences in the methanogen population exist in sika deer (Cervus nippon) fed different diets in China.	Li ZP, Liu HL, Jin CA, Cui XZ, Jing Y, Yang FH, Li GY, Wright AD.	Microb Ecol	10.1007/s00248-013-0282-4	2013
	Effects of live yeast on differential genetic and functional attributes of rumen microbiota in beef cattle.	Ogunade IM, Lay J, Andries K, McManus CJ, Bebe F.	J Anim Sci Biotechnol	10.1186/s40104-019-0378-x	2019
Enzymology	The effect of 3-nitrooxypropanol, a potent methane inhibitor, on ruminal microbial gene expression profiles in dairy cows.	Pitta DW, Indugu N, Melgar A, Hristov A, Challa K, Vecchiarelli B, Hennessy M, Narayan K, Duval S, Kindermann M, Walker N.	Microbiome	10.1186/s40168-022-01341-9	2022
	Characterization of natural co-cultures of Piromyces with Methanobrevibacter ruminantium from yaks grazing on the Qinghai-Tibetan Plateau: a microbial consortium with high potential in plant biomass degradation.	Wei YQ, Yang HJ, Long RJ, Wang ZY, Cao BB, Ren QC, Wu TT.	AMB Express	10.1186/s13568-017-0459-1	2017
	Proteomic and metabolomic profiling of extracellular vesicles produced by human gut archaea	Weinberger V, Darnhofer B, Thapa H, Mertelj P, Stentz R, Jones E, Grabmann G, Mohammadzadeh R, Shinde T, Karner C, Ober J, Juodeikis R, Pernitsch D, Hingerl K, Zurabishvili T, Kumpitsch C, Kuehnast T, Rinner B, Strohmaier H, Kolb D, Gotts K, Weichhart T, Kocher T, Kofeler H, Carding S, Schild S, Moissl-Eichinger C.	Nat Commun		2025
	Metagenomic Analysis of Fecal Archaea, Bacteria, Eukaryota, and Virus in Przewalski's Horses Following Anthelmintic Treatment.	Hu D, Yang J, Qi Y, Li B, Li K, Mok KM.	Front Vet Sci	10.3389/fvets.2021.708512	2021
Metabolism	Methanogen prevalence throughout the gastrointestinal tract of pre-weaned dairy calves.	Zhou M, Chen Y, Griebel PJ, Guan le L.	Gut Microbes	10.4161/19490976.2014.969649	2014
	Effect of olive and date palm by-products on rumen methanogenic community in Barki sheep.	Rabee AE, Kewan KZ, El Shaer HM, Lamara M, Sabra EA.	AIMS Microbiol	10.3934/microbiol.2022003	2022
	The archaeal and bacterial community structure in composted cow manures is defined by the original populations: a shotgun metagenomic approach.	Romero-Yahuitl V, Zarco-Gonzalez KE, Toriz-Nava AL, Hernandez M, Velazquez-Fernandez JB, Navarro-Noya YE, Luna-Guido M, Dendooven L.	Front Microbiol	10.3389/fmicb.2024.1425548	2024
Genetics	A Preliminary Study of the Potential Molecular Mechanisms of Individual Growth and Rumen Development in Calves with Different Feeding Patterns.	Wang J, Zhao K, Li M, Fan H, Wang M, Xia S, Chen Y, Bai X, Liu Z, Ni J, Sun W, Jia X, Lai S.	Microorganisms	10.3390/microorganisms11102423	2023
	High-throughput DNA sequencing of the moose rumen from different geographical locations reveals a core ruminal methanogenic archaeal diversity and a differential ciliate protozoal diversity.	Ishaq SL, Sundset MA, Crouse J, Wright AG.	Microb Genom	10.1099/mgen.0.000034	2015
Metabolism	Plane of nutrition affects the phylogenetic diversity and relative abundance of transcriptionally active methanogens in the bovine rumen.	McGovern E, McCabe MS, Cormican P, Popova M, Keogh K, Kelly AK, Kenny DA, Waters SM.	Sci Rep	10.1038/s41598-017-13013-y	2017
Metabolism	Co-abundance analysis reveals hidden players associated with high methane yield phenotype in sheep rumen microbiome.	Ghanbari Maman L, Palizban F, Fallah Atanaki F, Elmi Ghiasi N, Ariaeenejad S, Ghaffari MR, Hosseini Salekdeh G, Kavousi K.	Sci Rep	10.1038/s41598-020-61942-y	2020
Metabolism	Response of the Rumen Microbiota of Sika Deer (Cervus nippon) Fed Different Concentrations of Tannin Rich Plants.	Li Z, Wright AD, Liu H, Fan Z, Yang F, Zhang Z, Li G.	PLoS One	10.1371/journal.pone.0123481	2015
Metabolism	Differences in the rumen methanogen populations of lactating Jersey and Holstein dairy cows under the same diet regimen.	King EE, Smith RP, St-Pierre B, Wright AD.	Appl Environ Microbiol	10.1128/aem.05130-11	2011
	Exploring rumen methanogen genomes to identify targets for methane mitigation strategies	Attwood GT, Altermann E, Kelly WJ, Leahy SC, Zhang L, Morrison M.	Anim Feed Sci Technol	10.1016/j.anifeedsci.2011.04.004	2011
	Methanogen community structure in the rumens of farmed sheep, cattle and red deer fed different diets.	Jeyanathan J, Kirs M, Ronimus RS, Hoskin SO, Janssen PH.	FEMS Microbiol Ecol	10.1111/j.1574-6941.2011.01056.x	2011
Genetics	Response of soil microbial compositional and functional heterogeneity to grazing exclusion in alpine shrub and meadows in the Qinghai-Tibet Plateau.	Wang S, Abalori TA, Wang W, Deng X, Liu W, Wang J, Cao W.	Front Microbiol	10.3389/fmicb.2022.1038805	2022
Pathogenicity	Development of Multiwell-Plate Methods Using Pure Cultures of Methanogens To Identify New Inhibitors for Suppressing Ruminant Methane Emissions.	Weimar MR, Cheung J, Dey D, McSweeney C, Morrison M, Kobayashi Y, Whitman WB, Carbone V, Schofield LR, Ronimus RS, Cook GM.	Appl Environ Microbiol	10.1128/aem.00396-17	2017
Transcriptome	Metatranscriptomic Profiling Reveals Linkages between the Active Rumen Microbiome and Feed Efficiency in Beef Cattle.	Li F, Guan LL.	Appl Environ Microbiol	10.1128/aem.00061-17	2017
	Comparative genomic analysis of Methanimicrococcus blatticola provides insights into host adaptation in archaea and the evolution of methanogenesis.	Thomas CM, Taib N, Gribaldo S, Borrel G.	ISME Commun	10.1038/s43705-021-00050-y	2021
Phylogeny	Characteristics and Functions of the Rumen Microbial Community of Cattle-Yak at Different Ages.	Sha Y, Hu J, Shi B, Dingkao R, Wang J, Li S, Zhang W, Luo Y, Liu X.	Biomed Res Int	10.1155/2020/3482692	2020
Genetics	Revealing the developmental characterization of rumen microbiome and its host in newly received cattle during receiving period contributes to formulating precise nutritional strategies.	Li Y, Mao K, Zang Y, Lu G, Qiu Q, Ouyang K, Zhao X, Song X, Xu L, Liang H, Qu M.	Microbiome	10.1186/s40168-023-01682-z	2023
Enzymology	Anti-Methanogenic Effect of Phytochemicals on Methyl-Coenzyme M Reductase-Potential: In Silico and Molecular Docking Studies for Environmental Protection.	Dinakarkumar Y, Rajabathar JR, Arokiyaraj S, Jeyaraj I, Anjaneyulu SR, Sandeep S, Karthik CS, Appaturi JN, Wilson LD.	Micromachines (Basel)	10.3390/mi12111425	2021
Genetics	Bacillus subtilis and Macleaya cordata extract regulate the rumen microbiota associated with enteric methane emission in dairy cows.	Jia P, Dong LF, Tu Y, Diao QY.	Microbiome	10.1186/s40168-023-01654-3	2023
Enzymology	Methanobrevibacter ruminantium as an indicator of domesticated-ruminant fecal pollution in surface waters.	Ufnar JA, Wang SY, Ufnar DF, Ellender RD.	Appl Environ Microbiol	10.1128/aem.00911-07	2007
	Impact of Moringa oleifera Leaves on Nutrient Utilization, Enteric Methane Emissions, and Performance of Goat Kids.	Leitanthem VK, Chaudhary P, Maiti S, Mohini M, Mondal G.	Animals (Basel)	10.3390/ani13010097	2022
Phylogeny	Few highly abundant operational taxonomic units dominate within rumen methanogenic archaeal species in New Zealand sheep and cattle.	Seedorf H, Kittelmann S, Janssen PH.	Appl Environ Microbiol	10.1128/aem.03018-14	2015
	The effects of residual energy intake on nutrient use, methane emissions and microbial composition in dairy cows.	Ahvenjarvi S, Bayat AR, Toivanen M, Mantysaari P, Tapio I.	Sci Rep	10.1038/s41598-024-51300-7	2024
	Feeding an unsalable carrot total-mixed ration altered bacterial amino acid degradation in the rumen of lambs.	Forwood DL, Innes DJ, Parra MC, Stark T, de Souza DP, Chaves AV, Meale SJ.	Sci Rep	10.1038/s41598-023-34181-0	2023
Genetics	Rumen Microbiota Predicts Feed Efficiency of Primiparous Nordic Red Dairy Cows.	Tapio M, Fischer D, Mantysaari P, Tapio I.	Microorganisms	10.3390/microorganisms11051116	2023
Genetics	Metagenomic analysis provides bases on individualized shift of colon microbiome affected by delaying colostrum feeding in neonatal calves.	Song Y, Wen S, Li F, Fischer-Tlustos A, He Z, Guan LL, Steele M.	Front Microbiol	10.3389/fmicb.2022.1035331	2022
	The Historical Development of Cultivation Techniques for Methanogens and Other Strict Anaerobes and Their Application in Modern Microbiology.	Hanisakova N, Vitezova M, Rittmann SKR.	Microorganisms	10.3390/microorganisms10020412	2022
	Comparative analysis of macroalgae supplementation on the rumen microbial community: Asparagopsis taxiformis inhibits major ruminal methanogenic, fibrolytic, and volatile fatty acid-producing microbes in vitro.	O'Hara E, Terry SA, Moote P, Beauchemin KA, McAllister TA, Abbott DW, Gruninger RJ.	Front Microbiol	10.3389/fmicb.2023.1104667	2023
	Diversity, abundance and novel 16S rRNA gene sequences of methanogens in rumen liquid, solid and epithelium fractions of Jinnan cattle.	Pei CX, Mao SY, Cheng YF, Zhu WY.	Animal	10.1017/s1751731109990681	2010
	Reducing crude protein content in the diet of lactating dairy cows improved nitrogen-use-efficiency and reduced N excretion in urine, whilst having no obvious effects on the rumen microbiome	Zeleke A, Dimonaco N, Lawther K, Lavery A, Ferris C, Moorby J, Huws S.	J Anim Sci Biotechnol		2025
Metabolism	Satellites in the prokaryote world.	Subirana JA, Messeguer X.	BMC Evol Biol	10.1186/s12862-019-1504-2	2019
Phylogeny	Comparative analysis of the methanogen diversity in horse and pony by using mcrA gene and archaeal 16s rRNA gene clone libraries.	Lwin KO, Matsui H.	Archaea	10.1155/2014/483574	2014
Enzymology	Illumina MiSeq Phylogenetic Amplicon Sequencing Shows a Large Reduction of an Uncharacterised Succinivibrionaceae and an Increase of the Methanobrevibacter gottschalkii Clade in Feed Restricted Cattle.	McCabe MS, Cormican P, Keogh K, O'Connor A, O'Hara E, Palladino RA, Kenny DA, Waters SM.	PLoS One	10.1371/journal.pone.0133234	2015
Genetics	Simulated seasonal diets alter yak rumen microbiota structure and metabolic function.	Yang X, Fan X, Jiang H, Zhang Q, Basangwangdui, Zhang Q, Dang S, Long R, Huang X.	Front Microbiol	10.3389/fmicb.2022.1006285	2022
Metabolism	Comparative Analysis of the Microbiota Between Rumen and Duodenum of Twin Lambs Based on Diets of Ceratoides or Alfalfa.	Akonyani ZP, Song F, Li Y, Qiqige S, Wu J.	Pol J Microbiol	10.33073/pjm-2021-015	2021
Phylogeny	Analysis of methanogen diversity in the rumen using temporal temperature gradient gel electrophoresis: identification of uncultured methanogens.	Nicholson MJ, Evans PN, Joblin KN.	Microb Ecol	10.1007/s00248-006-9182-1	2007
	Inoculation with rumen fluid in early life accelerates the rumen microbial development and favours the weaning process in goats.	Palma-Hidalgo JM, Jimenez E, Popova M, Morgavi DP, Martin-Garcia AI, Yanez-Ruiz DR, Belanche A.	Anim Microbiome	10.1186/s42523-021-00073-9	2021
Phylogeny	Dietary pea fiber increases diversity of colonic methanogens of pigs with a shift from Methanobrevibacter to Methanomassiliicoccus-like genus and change in numbers of three hydrogenotrophs.	Luo Y, Chen H, Yu B, He J, Zheng P, Mao X, Tian G, Yu J, Huang Z, Luo J, Chen D.	BMC Microbiol	10.1186/s12866-016-0919-9	2017
Phylogeny	Phloroglucinol Degradation in the Rumen Promotes the Capture of Excess Hydrogen Generated from Methanogenesis Inhibition.	Martinez-Fernandez G, Denman SE, Cheung J, McSweeney CS.	Front Microbiol	10.3389/fmicb.2017.01871	2017
Metabolism	Rumen-like methanogens identified from the crop of the folivorous South American bird, the hoatzin (Opisthocomus hoazin).	Wright AD, Northwood KS, Obispo NE.	ISME J	10.1038/ismej.2009.41	2009
Enzymology	Rumen methanogenic genotypes differ in abundance according to host residual feed intake phenotype and diet type.	Carberry CA, Waters SM, Kenny DA, Creevey CJ.	Appl Environ Microbiol	10.1128/aem.03131-13	2014
	The effects of feeding ferric citrate on ruminal bacteria, methanogenic archaea and methane production in growing beef steers.	Clemmons BA, Schneider LG, Melchior EA, Lindholm-Perry AK, Hales KE, Wells JE, Freetly HC, Hansen SL, Drewnoski ME, Hartman SJ, Myer PR.	Access Microbiol	10.1099/acmi.0.000180	2021
Genetics	Methanobacterium formicicum as a target rumen methanogen for the development of new methane mitigation interventions: A review.	Chellapandi P, Bharathi M, Sangavai C, Prathiviraj R.	Vet Anim Sci	10.1016/j.vas.2018.09.001	2018
Pathogenicity	Effect of tea saponin on methanogenesis, microbial community structure and expression of mcrA gene, in cultures of rumen micro-organisms.	Guo YQ, Liu JX, Lu Y, Zhu WY, Denman SE, McSweeney CS.	Lett Appl Microbiol	10.1111/j.1472-765x.2008.02459.x	2008
Phylogeny	Molecular phylogenetics before sequences: oligonucleotide catalogs as k-mer spectra.	Ragan MA, Bernard G, Chan CX.	RNA Biol	10.4161/rna.27505	2014
Genetics	The Remodeling Effects of High-Concentrate Diets on Microbial Composition and Function in the Hindgut of Dairy Cows.	Zhang R, Liu J, Jiang L, Wang X, Mao S.	Front Nutr	10.3389/fnut.2021.809406	2021
Phylogeny	Toward the identification of methanogenic archaeal groups as targets of methane mitigation in livestock animalsr.	St-Pierre B, Cersosimo LM, Ishaq SL, Wright AD.	Front Microbiol	10.3389/fmicb.2015.00776	2015
	Enhancing the Resolution of Rumen Microbial Classification from Metatranscriptomic Data Using Kraken and Mothur.	Neves ALA, Li F, Ghoshal B, McAllister T, Guan LL.	Front Microbiol	10.3389/fmicb.2017.02445	2017
Phylogeny	Genome-Wide Analysis Reveals Ancestral Lack of Seventeen Different tRNAs and Clade-Specific Loss of tRNA-CNNs in Archaea.	Wu Y, Wu P, Wang B, Shao ZQ.	Front Microbiol	10.3389/fmicb.2018.01245	2018
	Illumina MiSeq sequencing reveals the effects of grape seed procyanidin on rumen archaeal communities in vitro.	Zhang H, Tong J, Wang Z, Xiong B, Jiang L.	Asian-Australas J Anim Sci	10.5713/ajas.19.0226	2020
	Effects of steam-flaked grains on foals' growth and faecal microbiota.	Li XB, Huang XX, Zang CJ, Ma C, Chen KX, Zhao GD, Li Q, Li XY, Zhang WJ, Yang KL.	BMC Vet Res	10.1186/s12917-021-02994-8	2021
Phylogeny	Molecular analysis of methanogenic archaea in the forestomach of the alpaca (Vicugna pacos).	St-Pierre B, Wright AD.	BMC Microbiol	10.1186/1471-2180-12-1	2012
Metabolism	Community structure of the metabolically active rumen bacterial and archaeal communities of dairy cows over the transition period.	Zhu Z, Noel SJ, Difford GF, Al-Soud WA, Brejnrod A, Sorensen SJ, Lassen J, Lovendahl P, Hojberg O.	PLoS One	10.1371/journal.pone.0187858	2017
	Effect of Long-Term Supplementation With Silkworm Pupae Oil on the Methane Yield, Ruminal Protozoa, and Archaea Community in Sheep.	Thirumalaisamy G, Malik PK, Trivedi S, Kolte AP, Bhatta R.	Front Microbiol	10.3389/fmicb.2022.780073	2022
	Pretreatments of Broussonetia papyrifera: in vitro assessment on gas and methane production, fermentation characteristic, and methanogenic archaea profile.	Dong L, Gao Y, Jing X, Guo H, Zhang H, Lai Q, Diao Q.	Anim Biosci	10.5713/ajas.20.0503	2022
Pathogenicity	Host genetics influence the rumen microbiota and heritable rumen microbial features associate with feed efficiency in cattle.	Li F, Li C, Chen Y, Liu J, Zhang C, Irving B, Fitzsimmons C, Plastow G, Guan LL.	Microbiome	10.1186/s40168-019-0699-1	2019
Phylogeny	Taxon abundance, diversity, co-occurrence and network analysis of the ruminal microbiota in response to dietary changes in dairy cows.	Tapio I, Fischer D, Blasco L, Tapio M, Wallace RJ, Bayat AR, Ventto L, Kahala M, Negussie E, Shingfield KJ, Vilkki J.	PLoS One	10.1371/journal.pone.0180260	2017
	Biochemical Properties of Black and Green Teas and Their Insoluble Residues as Natural Dietary Additives to Optimize In Vitro Rumen Degradability and Fermentation but Reduce Methane in Sheep.	Ramdani D, Jayanegara A, Chaudhry AS.	Animals (Basel)	10.3390/ani12030305	2022
Enzymology	Mode of action uncovered for the specific reduction of methane emissions from ruminants by the small molecule 3-nitrooxypropanol.	Duin EC, Wagner T, Shima S, Prakash D, Cronin B, Yanez-Ruiz DR, Duval S, Rumbeli R, Stemmler RT, Thauer RK, Kindermann M.	Proc Natl Acad Sci U S A	10.1073/pnas.1600298113	2016
	Effect of castration timing and weaning strategy on the taxonomic and functional profile of ruminal bacteria and archaea of beef calves.	Diaz GR, Gaire TN, Ferm P, Case L, Caixeta LS, Goldsmith TJ, Armstrong J, Noyes NR.	Anim Microbiome	10.1186/s42523-023-00284-2	2023
Metabolism	Effects of several inhibitors on pure cultures of ruminal methanogens.	Ungerfeld EM, Rust SR, Boone DR, Liu Y.	J Appl Microbiol	10.1111/j.1365-2672.2004.02330.x	2004
	Three-Source Partitioning of Methane Emissions from Paddy Soil: Linkage to Methanogenic Community Structure.	Yuan J, Yi X, Cao L.	Int J Mol Sci	10.3390/ijms20071586	2019
	Diversity and taxonomic revision of methanogens and other archaea in the intestinal tract of terrestrial arthropods.	Protasov E, Nonoh JO, Kastle Silva JM, Mies US, Herve V, Dietrich C, Lang K, Mikulski L, Platt K, Poehlein A, Kohler-Ramm T, Miambi E, Boga HI, Feldewert C, Ngugi DK, Plarre R, Sillam-Dusses D, Sobotnik J, Daniel R, Brune A.	Front Microbiol	10.3389/fmicb.2023.1281628	2023
	CRISPR sequences are sometimes erroneously translated and can contaminate public databases with spurious proteins containing spaced repeats.	Rubio A, Mier P, Andrade-Navarro MA, Garzon A, Jimenez J, Perez-Pulido AJ.	Database (Oxford)	10.1093/database/baaa088	2020
Metabolism	Methanogenesis in the Digestive Tracts of the Tropical Millipedes Archispirostreptus gigas (Diplopoda, Spirostreptidae) and Epibolus pulchripes (Diplopoda, Pachybolidae).	Horvathova T, Sustr V, Chronakova A, Semanova S, Lang K, Dietrich C, Hubacek T, Ardestani MM, Lara AC, Brune A, Simek M.	Appl Environ Microbiol	10.1128/aem.00614-21	2021
Enzymology	Lean breed Landrace pigs harbor fecal methanogens at higher diversity and density than obese breed Erhualian pigs.	Luo YH, Su Y, Wright AD, Zhang LL, Smidt H, Zhu WY.	Archaea	10.1155/2012/605289	2012
Enzymology	The Composition of Fungal Communities in the Rumen of Gayals (Bos frontalis), Yaks (Bos grunniens), and Yunnan and Tibetan Yellow Cattle (Bos taurs).	Wang H, Li P, Liu X, Zhang C, Lu Q, Xi D, Yang R, Wang S, Bai W, Yang Z, Zhou R, Cheng X, Leng J.	Pol J Microbiol	10.33073/pjm-2019-050	2019
	Impact of inulin and yeast containing synbiotic on calves' productivity and greenhouse gas production.	Jonova S, Ilgaza A, Zolovs M, Balins A.	Vet World	10.14202/vetworld.2020.1017-1024	2020
Metabolism	Characterization of variation in rumen methanogenic communities under different dietary and host feed efficiency conditions, as determined by PCR-denaturing gradient gel electrophoresis analysis.	Zhou M, Hernandez-Sanabria E, Guan LL.	Appl Environ Microbiol	10.1128/aem.00010-10	2010
	The complete genome sequence of the rumen methanogen Methanosarcina barkeri CM1.	Lambie SC, Kelly WJ, Leahy SC, Li D, Reilly K, McAllister TA, Valle ER, Attwood GT, Altermann E.	Stand Genomic Sci	10.1186/s40793-015-0038-5	2015
	Ruminal fermentation and microbial community differently influenced by four typical subtropical forages in vitro.	Iqbal MW, Zhang Q, Yang Y, Zou C, Li L, Liang X, Wei S, Lin B.	Anim Nutr	10.1016/j.aninu.2017.10.005	2018
Metabolism	Molecular diversity of methanogens in feedlot cattle from Ontario and Prince Edward Island, Canada.	Wright AD, Auckland CH, Lynn DH.	Appl Environ Microbiol	10.1128/aem.00103-07	2007
	Maternal versus artificial rearing shapes the rumen microbiome having minor long-term physiological implications.	Belanche A, Yanez-Ruiz DR, Detheridge AP, Griffith GW, Kingston-Smith AH, Newbold CJ.	Environ Microbiol	10.1111/1462-2920.14801	2019
	The streptothricin acetyltransferase (sat) gene as a positive selectable marker for methanogenic archaea.	Farley KR, Metcalf WW.	FEMS Microbiol Lett	10.1093/femsle/fnz216	2019
	Simultaneous amplicon sequencing to explore co-occurrence patterns of bacterial, archaeal and eukaryotic microorganisms in rumen microbial communities.	Kittelmann S, Seedorf H, Walters WA, Clemente JC, Knight R, Gordon JI, Janssen PH.	PLoS One	10.1371/journal.pone.0047879	2013
Metabolism	Comparison of enteric methane yield and diversity of ruminal methanogens in cattle and buffaloes fed on the same diet.	Malik PK, Trivedi S, Mohapatra A, Kolte AP, Sejian V, Bhatta R, Rahman H.	PLoS One	10.1371/journal.pone.0256048	2021
Enzymology	Phylogenetic analysis of methyl coenzyme-M reductase detected from the bovine rumen.	Tatsuoka N, Mohammed N, Mitsumori M, Hara K, Kurihara M, Itabashi H.	Lett Appl Microbiol	10.1111/j.1472-765x.2004.01566.x	2004
	Molecular Genetic Diversity and Quantitation of Methanogen in Ruminal Fluid of Buffalo (Bubalus bubalis) Fed Ration (Wheat Straw and Concentrate Mixture Diet).	Singh KM, Tripathi AK, Pandya PR, Parnerkar S, Kothari RK, Joshi CG.	Genet Res Int	10.1155/2013/980191	2013
Pathogenicity	Effects of the Fusarium spp. mycotoxins fusaric acid and deoxynivalenol on the growth of Ruminococcus albus and Methanobrevibacter ruminantium.	May HD, Wu Q, Blake CK.	Can J Microbiol	10.1139/w00-045	2000
	The structure of microbial populations in Nelore GIT reveals inter-dependency of methanogens in feces and rumen.	Andrade BGN, Bressani FA, Cuadrat RRC, Tizioto PC, de Oliveira PSN, Mourao GB, Coutinho LL, Reecy JM, Koltes JE, Walsh P, Berndt A, Palhares JCP, Regitano LCA.	J Anim Sci Biotechnol	10.1186/s40104-019-0422-x	2020
	In Vitro Incubations Do Not Reflect In Vivo Differences Based on Ranking of Low and High Methane Emitters in Dairy Cows.	Cabezas-Garcia EH, Danielsson R, Ramin M, Huhtanen P.	Animals (Basel)	10.3390/ani11113112	2021
Phylogeny	Isolation and characterization of a new Methanoculleus bourgensis strain KOR-2 from the rumen of Holstein steers.	Battumur U, Lee M, Bae GS, Kim CH.	Asian-Australas J Anim Sci	10.5713/ajas.18.0409	2019
	Distribution of Peptidyl-Prolyl Isomerase (PPIase) in the Archaea.	Anchal, Kaushik V, Goel M.	Front Microbiol	10.3389/fmicb.2021.751049	2021
	Peri-implantitis-associated methanogens: a preliminary report.	Belkacemi S, Mazel A, Tardivo D, Tavitian P, Stephan G, Bianca G, Terrer E, Drancourt M, Aboudharam G.	Sci Rep	10.1038/s41598-018-27862-8	2018
Phylogeny	Comparison of methanogen diversity of yak (Bos grunniens) and cattle (Bos taurus) from the Qinghai-Tibetan plateau, China.	Huang XD, Tan HY, Long R, Liang JB, Wright AD.	BMC Microbiol	10.1186/1471-2180-12-237	2012
	CRISPRDetect: A flexible algorithm to define CRISPR arrays.	Biswas A, Staals RH, Morales SE, Fineran PC, Brown CM.	BMC Genomics	10.1186/s12864-016-2627-0	2016
	Investigation into the effect of divergent feed efficiency phenotype on the bovine rumen microbiota across diet and breed.	McGovern E, McGee M, Byrne CJ, Kenny DA, Kelly AK, Waters SM.	Sci Rep	10.1038/s41598-020-71458-0	2020
Metabolism	Application of pseudomurein endoisopeptidase to fluorescence in situ hybridization of methanogens within the family Methanobacteriaceae.	Nakamura K, Terada T, Sekiguchi Y, Shinzato N, Meng XY, Enoki M, Kamagata Y.	Appl Environ Microbiol	10.1128/aem.01499-06	2006
	Microbiome Aggregated Traits and Assembly Are More Sensitive to Soil Management than Diversity.	Neal AL, Hughes D, Clark IM, Jansson JK, Hirsch PR.	mSystems	10.1128/msystems.01056-20	2021
Metabolism	Fibrolytic rumen bacteria of camel and sheep and their applications in the bioconversion of barley straw to soluble sugars for biofuel production.	Rabee AE, Sayed Alahl AA, Lamara M, Ishaq SL.	PLoS One	10.1371/journal.pone.0262304	2022
Pathogenicity	Using Structural Equation Modeling to Understand Interactions Between Bacterial and Archaeal Populations and Volatile Fatty Acid Proportions in the Rumen.	Kaplan-Shabtai V, Indugu N, Hennessy ML, Vecchiarelli B, Bender JS, Stefanovski D, De Assis Lage CF, Raisanen SE, Melgar A, Nedelkov K, Fetter ME, Fernandez A, Spitzer A, Hristov AN, Pitta DW.	Front Microbiol	10.3389/fmicb.2021.611951	2021
Metabolism	Identification of rumen microbial biomarkers linked to methane emission in Holstein dairy cows.	Ramayo-Caldas Y, Zingaretti L, Popova M, Estelle J, Bernard A, Pons N, Bellot P, Mach N, Rau A, Roume H, Perez-Enciso M, Faverdin P, Edouard N, Ehrlich D, Morgavi DP, Renand G.	J Anim Breed Genet	10.1111/jbg.12427	2020
	Effectiveness of decontamination protocols when analyzing ancient DNA preserved in dental calculus.	Farrer AG, Wright SL, Skelly E, Eisenhofer R, Dobney K, Weyrich LS.	Sci Rep	10.1038/s41598-021-86100-w	2021
Phylogeny	Heterogeneous development of methanogens and the correlation with bacteria in the rumen and cecum of sika deer (Cervus nippon) during early life suggest different ecology relevance.	Li Z, Wang X, Zhang T, Si H, Xu C, Wright AG, Li G.	BMC Microbiol	10.1186/s12866-019-1504-9	2019
	Taxonomic Assessment of Rumen Microbiota Using Total RNA and Targeted Amplicon Sequencing Approaches.	Li F, Henderson G, Sun X, Cox F, Janssen PH, Guan le L.	Front Microbiol	10.3389/fmicb.2016.00987	2016
Pathogenicity	Fungal species and mycotoxins in mouldy spots of grass and maize silages in Austria.	Penagos-Tabares F, Khiaosa-Ard R, Schmidt M, Pacifico C, Faas J, Jenkins T, Nagl V, Sulyok M, Labuda R, Zebeli Q.	Mycotoxin Res	10.1007/s12550-022-00453-3	2022
	Advanced estimation and mitigation strategies: a cumulative approach to enteric methane abatement from ruminants.	Islam M, Lee SS.	J Anim Sci Technol	10.5187/jast.2019.61.3.122	2019
Genetics	Metagenomic analysis of ancient dental calculus reveals unexplored diversity of oral archaeal Methanobrevibacter.	Granehall L, Huang KD, Tett A, Manghi P, Paladin A, O'Sullivan N, Rota-Stabelli O, Segata N, Zink A, Maixner F.	Microbiome	10.1186/s40168-021-01132-8	2021
Phylogeny	A 'universal' type II chaperonin PCR detection system for the investigation of Archaea in complex microbial communities.	Chaban B, Hill JE.	ISME J	10.1038/ismej.2011.96	2012
Pathogenicity	Comparative Microbiome Analysis Reveals the Ecological Relationships Between Rumen Methanogens, Acetogens, and Their Hosts.	Li Z, Wang X, Alberdi A, Deng J, Zhong Z, Si H, Zheng C, Zhou H, Wang J, Yang Y, Wright AG, Mao S, Zhang Z, Guan L, Li G.	Front Microbiol	10.3389/fmicb.2020.01311	2020
Phylogeny	The Draft Genome of the Non-Host-Associated Methanobrevibacter arboriphilus Strain DH1 Encodes a Large Repertoire of Adhesin-Like Proteins.	Poehlein A, Daniel R, Seedorf H.	Archaea	10.1155/2017/4097425	2017
Phylogeny	Phylogenetic study of methanogens associated with rumen ciliates.	Tokura M, Chagan I, Ushida K, Kojima Y.	Curr Microbiol	10.1007/s002849900432	1999
Metabolism	Bacteria and methanogens differ along the gastrointestinal tract of Chinese roe deer (Capreolus pygargus).	Li Z, Zhang Z, Xu C, Zhao J, Liu H, Fan Z, Yang F, Wright AD, Li G.	PLoS One	10.1371/journal.pone.0114513	2014
Enzymology	Effect of DNA extraction methods and sampling techniques on the apparent structure of cow and sheep rumen microbial communities.	Henderson G, Cox F, Kittelmann S, Miri VH, Zethof M, Noel SJ, Waghorn GC, Janssen PH.	PLoS One	10.1371/journal.pone.0074787	2013
	Dose-Response Effects of 3-Nitrooxypropanol Combined with Low- and High-Concentrate Feed Proportions in the Dairy Cow Ration on Fermentation Parameters in a Rumen Simulation Technique.	Schilde M, von Soosten D, Huther L, Kersten S, Meyer U, Zeyner A, Danicke S.	Animals (Basel)	10.3390/ani11061784	2021
	Gut microbiome differences between wild and captive black rhinoceros - implications for rhino health.	Gibson KM, Nguyen BN, Neumann LM, Miller M, Buss P, Daniels S, Ahn MJ, Crandall KA, Pukazhenthi B.	Sci Rep	10.1038/s41598-019-43875-3	2019
	Vaccination of Sheep with a Methanogen Protein Provides Insight into Levels of Antibody in Saliva Needed to Target Ruminal Methanogens.	Subharat S, Shu D, Zheng T, Buddle BM, Kaneko K, Hook S, Janssen PH, Wedlock DN.	PLoS One	10.1371/journal.pone.0159861	2016
Metabolism	Betaine Modulates Rumen Archaeal Community and Functioning during Heat and Osmotic Stress Conditions In Vitro.	Mahmood M, Khiaosa-Ard R, Zebeli Q, Petri RM.	Archaea	10.1155/2020/8875773	2020
Phylogeny	Long-term monensin supplementation does not significantly affect the quantity or diversity of methanogens in the rumen of the lactating dairy cow.	Hook SE, Northwood KS, Wright AD, McBride BW.	Appl Environ Microbiol	10.1128/aem.01672-08	2009
Metabolism	Rumen and Cecum Microbiomes in Reindeer (Rangifer tarandus tarandus) Are Changed in Response to a Lichen Diet and May Affect Enteric Methane Emissions.	Salgado-Flores A, Hagen LH, Ishaq SL, Zamanzadeh M, Wright AD, Pope PB, Sundset MA.	PLoS One	10.1371/journal.pone.0155213	2016
	Diversity and community composition of methanogenic archaea in the rumen of Scottish upland sheep assessed by different methods.	Snelling TJ, Genc B, McKain N, Watson M, Waters SM, Creevey CJ, Wallace RJ.	PLoS One	10.1371/journal.pone.0106491	2014
	The Nasopharyngeal, Ruminal, and Vaginal Microbiota and the Core Taxa Shared across These Microbiomes in Virgin Yearling Heifers Exposed to Divergent In Utero Nutrition during Their First Trimester of Gestation and in Pregnant Beef Heifers in Response to Mineral Supplementation.	Amat S, Holman DB, Schmidt K, Menezes ACB, Baumgaertner F, Winders T, Kirsch JD, Liu T, Schwinghamer TD, Sedivec KK, Dahlen CR.	Microorganisms	10.3390/microorganisms9102011	2021
Enzymology	Characterization of bioaerosols from dairy barns: reconstructing the puzzle of occupational respiratory diseases by using molecular approaches.	Blais Lecours P, Veillette M, Marsolais D, Duchaine C.	Appl Environ Microbiol	10.1128/aem.07661-11	2012
	Isolation of cellulose-degrading bacteria and determination of their cellulolytic potential.	Gupta P, Samant K, Sahu A.	Int J Microbiol	10.1155/2012/578925	2012
	Secondary Structural Model of Human MALAT1 Reveals Multiple Structure-Function Relationships.	McCown PJ, Wang MC, Jaeger L, Brown JA.	Int J Mol Sci	10.3390/ijms20225610	2019
Metabolism	Rumen methanogen and protozoal communities of Tibetan sheep and Gansu Alpine Finewool sheep grazing on the Qinghai-Tibetan Plateau, China.	Huang J, Li Y.	BMC Microbiol	10.1186/s12866-018-1351-0	2018
	Fresh Rumen Liquid Inoculant Enhances the Rumen Microbial Community Establishment in Pre-weaned Dairy Calves.	Huuki H, Ahvenjarvi S, Lidauer P, Popova M, Vilkki J, Vanhatalo A, Tapio I.	Front Microbiol	10.3389/fmicb.2021.758395	2021
	Interactions between Anaerobic Fungi and Methanogens in the Rumen and Their Biotechnological Potential in Biogas Production from Lignocellulosic Materials.	Li Y, Meng Z, Xu Y, Shi Q, Ma Y, Aung M, Cheng Y, Zhu W.	Microorganisms	10.3390/microorganisms9010190	2021
Phylogeny	Genomic expansion of magnetotactic bacteria reveals an early common origin of magnetotaxis with lineage-specific evolution.	Lin W, Zhang W, Zhao X, Roberts AP, Paterson GA, Bazylinski DA, Pan Y.	ISME J	10.1038/s41396-018-0098-9	2018
	Influence of Diet Composition on Cattle Rumen Methanogenesis: A Comparative Metagenomic Analysis in Indian and Exotic Cattle.	Parmar NR, Pandit PD, Purohit HJ, Nirmal Kumar JI, Joshi CG.	Indian J Microbiol	10.1007/s12088-016-0635-z	2017
Phylogeny	Rumen Microbiome Composition Is Altered in Sheep Divergent in Feed Efficiency.	McLoughlin S, Spillane C, Claffey N, Smith PE, O'Rourke T, Diskin MG, Waters SM.	Front Microbiol	10.3389/fmicb.2020.01981	2020
Phylogeny	Faecal microbiota of forage-fed horses in New Zealand and the population dynamics of microbial communities following dietary change.	Fernandes KA, Kittelmann S, Rogers CW, Gee EK, Bolwell CF, Bermingham EN, Thomas DG.	PLoS One	10.1371/journal.pone.0112846	2014
	Rumen methanogens and mitigation of methane emission by anti-methanogenic compounds and substances.	Patra A, Park T, Kim M, Yu Z.	J Anim Sci Biotechnol	10.1186/s40104-017-0145-9	2017
Enzymology	Haloferax volcanii N-glycosylation: delineating the pathway of dTDP-rhamnose biosynthesis.	Kaminski L, Eichler J.	PLoS One	10.1371/journal.pone.0097441	2014
Genetics	Metabolic Modeling Elucidates the Transactions in the Rumen Microbiome and the Shifts Upon Virome Interactions.	Islam MM, Fernando SC, Saha R.	Front Microbiol	10.3389/fmicb.2019.02412	2019
	Effects of Fermented Herbal Tea Residues on the Intestinal Microbiota Characteristics of Holstein Heifers Under Heat Stress.	Xie Y, Chen Z, Wang D, Chen G, Sun X, He Q, Luo J, Chen T, Xi Q, Zhang Y, Sun J.	Front Microbiol	10.3389/fmicb.2020.01014	2020
Enzymology	Molecular diversity of rumen methanogens from sheep in Western Australia.	Wright AD, Williams AJ, Winder B, Christophersen CT, Rodgers SL, Smith KD.	Appl Environ Microbiol	10.1128/aem.70.3.1263-1270.2004	2004
Metabolism	Co-Occurrence of Regulated and Emerging Mycotoxins in Corn Silage: Relationships with Fermentation Quality and Bacterial Communities.	Gallo A, Ghilardelli F, Atzori AS, Zara S, Novak B, Faas J, Fancello F.	Toxins (Basel)	10.3390/toxins13030232	2021
Genetics	Deconstruction of archaeal genome depict strategic consensus in core pathways coding sequence assembly.	Pal A, Banerjee R, Mondal UK, Mukhopadhyay S, Bothra AK.	PLoS One	10.1371/journal.pone.0118245	2015
	Assessment of Ruminal Bacterial and Archaeal Community Structure in Yak (Bos grunniens).	Zhou Z, Fang L, Meng Q, Li S, Chai S, Liu S, Schonewille JT.	Front Microbiol	10.3389/fmicb.2017.00179	2017
Metabolism	The rumen microbial metaproteome as revealed by SDS-PAGE.	Snelling TJ, Wallace RJ.	BMC Microbiol	10.1186/s12866-016-0917-y	2017
	Correlation coefficients between different methods of expressing bacterial quantification using real time PCR.	Navidshad B, Liang JB, Jahromi MF.	Int J Mol Sci	10.3390/ijms13022119	2012
	Evaluating Strategies to Reduce Ruminal Protozoa and Their Impacts on Nutrient Utilization and Animal Performance in Ruminants - A Meta-Analysis.	Dai X, Faciola AP.	Front Microbiol	10.3389/fmicb.2019.02648	2019
Enzymology	Assessment of the microbial ecology of ruminal methanogens in cattle with different feed efficiencies.	Zhou M, Hernandez-Sanabria E, Guan LL.	Appl Environ Microbiol	10.1128/aem.02815-08	2009
Enzymology	A c subunit with four transmembrane helices and one ion (Na+)-binding site in an archaeal ATP synthase: implications for c ring function and structure.	Mayer F, Leone V, Langer JD, Faraldo-Gomez JD, Muller V.	J Biol Chem	10.1074/jbc.m112.411223	2012
Metabolism	Enteric methane production and ruminal fermentation of forage brassica diets fed in continuous culture.	Dillard SL, Roca-Fernandez AI, Rubano MD, Elkin KR, Soder KJ.	J Anim Sci	10.1093/jas/sky030	2018
Metabolism	Is coenzyme M bound to factor F430 in methanogenic bacteria? Experiments with Methanobrevibacter ruminantium.	Huster R, Gilles HH, Thauer RK.	Eur J Biochem	10.1111/j.1432-1033.1985.tb08813.x	1985
Metabolism	Diverse hydrogen production and consumption pathways influence methane production in ruminants.	Greening C, Geier R, Wang C, Woods LC, Morales SE, McDonald MJ, Rushton-Green R, Morgan XC, Koike S, Leahy SC, Kelly WJ, Cann I, Attwood GT, Cook GM, Mackie RI.	ISME J	10.1038/s41396-019-0464-2	2019
Metabolism	Non-autotrophic methanogens dominate in anaerobic digesters.	Kouzuma A, Tsutsumi M, Ishii S, Ueno Y, Abe T, Watanabe K.	Sci Rep	10.1038/s41598-017-01752-x	2017
	tRNAscan-SE 2.0: improved detection and functional classification of transfer RNA genes.	Chan PP, Lin BY, Mak AJ, Lowe TM.	Nucleic Acids Res	10.1093/nar/gkab688	2021
	Anaerobic Transformation of Furfural by Methanococcus deltae (Delta)LH.	Belay N, Boopathy R, Voskuilen G.	Appl Environ Microbiol	10.1128/aem.63.5.2092-2094.1997	1997
Phylogeny	Diversity and functions of the sheep faecal microbiota: a multi-omic characterization.	Tanca A, Fraumene C, Manghina V, Palomba A, Abbondio M, Deligios M, Pagnozzi D, Addis MF, Uzzau S.	Microb Biotechnol	10.1111/1751-7915.12462	2017
Metabolism	Identification of a unique radical S-adenosylmethionine methylase likely involved in methanopterin biosynthesis in Methanocaldococcus jannaschii.	Allen KD, Xu H, White RH.	J Bacteriol	10.1128/jb.01903-14	2014
Metabolism	Effects of flavonoids on rumen fermentation activity, methane production, and microbial population.	Oskoueian E, Abdullah N, Oskoueian A.	Biomed Res Int	10.1155/2013/349129	2013
	Application of Mootral^TM Reduces Methane Production by Altering the Archaea Community in the Rumen Simulation Technique.	Eger M, Graz M, Riede S, Breves G.	Front Microbiol	10.3389/fmicb.2018.02094	2018
Pathogenicity	Tithonia diversifolia as a Supplementary Feed for Dairy Cows.	Ribeiro RS, Terry SA, Sacramento JP, Silveira SR, Bento CB, da Silva EF, Mantovani HC, Gama MA, Pereira LG, Tomich TR, Mauricio RM, Chaves AV.	PLoS One	10.1371/journal.pone.0165751	2016
Metabolism	Differences down-under: alcohol-fueled methanogenesis by archaea present in Australian macropodids.	Hoedt EC, Cuiv PO, Evans PN, Smith WJ, McSweeney CS, Denman SE, Morrison M.	ISME J	10.1038/ismej.2016.41	2016
Phylogeny	Postinoculation protozoan establishment and association patterns of methanogenic archaea in the ovine rumen.	Ohene-Adjei S, Teather RM, Ivan M, Forster RJ.	Appl Environ Microbiol	10.1128/aem.02687-06	2007
	A Multi-Kingdom Study Reveals the Plasticity of the Rumen Microbiota in Response to a Shift From Non-grazing to Grazing Diets in Sheep.	Belanche A, Kingston-Smith AH, Griffith GW, Newbold CJ.	Front Microbiol	10.3389/fmicb.2019.00122	2019
	Quantitative analysis of ruminal methanogenic microbial populations in beef cattle divergent in phenotypic residual feed intake (RFI) offered contrasting diets.	Carberry CA, Kenny DA, Kelly AK, Waters SM.	J Anim Sci Biotechnol	10.1186/2049-1891-5-41	2014
Metabolism	Influence of sire breed on the interplay among rumen microbial populations inhabiting the rumen liquid of the progeny in beef cattle.	Hernandez-Sanabria E, Goonewardene LA, Wang Z, Zhou M, Moore SS, Guan LL.	PLoS One	10.1371/journal.pone.0058461	2013
Metabolism	Specific microbiome-dependent mechanisms underlie the energy harvest efficiency of ruminants.	Shabat SK, Sasson G, Doron-Faigenboim A, Durman T, Yaacoby S, Berg Miller ME, White BA, Shterzer N, Mizrahi I.	ISME J	10.1038/ismej.2016.62	2016
	Archaea in symbioses.	Wrede C, Dreier A, Kokoschka S, Hoppert M.	Archaea	10.1155/2012/596846	2012
	Hops (Humulus lupulus L.) Bitter Acids: Modulation of Rumen Fermentation and Potential As an Alternative Growth Promoter.	Flythe MD, Kagan IA, Wang Y, Narvaez N.	Front Vet Sci	10.3389/fvets.2017.00131	2017
Pathogenicity	An inhibitor persistently decreased enteric methane emission from dairy cows with no negative effect on milk production.	Hristov AN, Oh J, Giallongo F, Frederick TW, Harper MT, Weeks HL, Branco AF, Moate PJ, Deighton MH, Williams SR, Kindermann M, Duval S.	Proc Natl Acad Sci U S A	10.1073/pnas.1504124112	2015
Enzymology	Characteristics of methanogens isolated from bovine rumen.	Miller TL, Wolin MJ, Zhao HX, Bryant MP.	Appl Environ Microbiol	10.1128/aem.51.1.201-202.1986	1986
Enzymology	Birth of Archaeal Cells: Molecular Phylogenetic Analyses of G1P Dehydrogenase, G3P Dehydrogenases, and Glycerol Kinase Suggest Derived Features of Archaeal Membranes Having G1P Polar Lipids.	Yokobori SI, Nakajima Y, Akanuma S, Yamagishi A.	Archaea	10.1155/2016/1802675	2016
Phylogeny	Comparative metagenomic and metatranscriptomic analyses reveal the breed effect on the rumen microbiome and its associations with feed efficiency in beef cattle.	Li F, Hitch TCA, Chen Y, Creevey CJ, Guan LL.	Microbiome	10.1186/s40168-019-0618-5	2019
Metabolism	Na+ transport by the A1AO-ATP synthase purified from Thermococcus onnurineus and reconstituted into liposomes.	Mayer F, Lim JK, Langer JD, Kang SG, Muller V.	J Biol Chem	10.1074/jbc.m114.616862	2015
	Dynamics of a pig slurry microbial community during anaerobic storage and management.	Peu P, Brugere H, Pourcher AM, Kerouredan M, Godon JJ, Delgenes JP, Dabert P.	Appl Environ Microbiol	10.1128/aem.72.5.3578-3585.2006	2006
Metabolism	Lambs fed fresh winter forage rape (Brassica napus L.) emit less methane than those fed perennial ryegrass (Lolium perenne L.), and possible mechanisms behind the difference.	Sun X, Henderson G, Cox F, Molano G, Harrison SJ, Luo D, Janssen PH, Pacheco D.	PLoS One	10.1371/journal.pone.0119697	2015
Metabolism	Characterization of a novel eukaryal nick-sealing RNA ligase from Naegleria gruberi.	Unciuleac MC, Shuman S.	RNA	10.1261/rna.049197.114	2015
Genetics	Methane yield phenotypes linked to differential gene expression in the sheep rumen microbiome.	Shi W, Moon CD, Leahy SC, Kang D, Froula J, Kittelmann S, Fan C, Deutsch S, Gagic D, Seedorf H, Kelly WJ, Atua R, Sang C, Soni P, Li D, Pinares-Patino CS, McEwan JC, Janssen PH, Chen F, Visel A, Wang Z, Attwood GT, Rubin EM.	Genome Res	10.1101/gr.168245.113	2014
	Methanosarcina Spherical Virus, a Novel Archaeal Lytic Virus Targeting Methanosarcina Strains.	Weidenbach K, Nickel L, Neve H, Alkhnbashi OS, Kunzel S, Kupczok A, Bauersachs T, Cassidy L, Tholey A, Backofen R, Schmitz RA.	J Virol	10.1128/jvi.00955-17	2017
Genetics	A Comprehensive tRNA Genomic Survey Unravels the Evolutionary History of tRNA Arrays in Prokaryotes.	Tran TT, Belahbib H, Bonnefoy V, Talla E.	Genome Biol Evol	10.1093/gbe/evv254	2015
Metabolism	Effects of 3'-OH and 5'-PO4 base mispairs and damaged base lesions on the fidelity of nick sealing by Deinococcus radiodurans RNA ligase.	Schmier BJ, Shuman S.	J Bacteriol	10.1128/jb.00020-14	2014
Enzymology	Fibrolytic Bacteria Isolated from the Rumen of North American Moose (Alces alces) and Their Use as a Probiotic in Neonatal Lambs.	Ishaq SL, Kim CJ, Reis D, Wright AD.	PLoS One	10.1371/journal.pone.0144804	2015
	Effect of Pre-weaning Diet on the Ruminal Archaeal, Bacterial, and Fungal Communities of Dairy Calves.	Dias J, Marcondes MI, Noronha MF, Resende RT, Machado FS, Mantovani HC, Dill-McFarland KA, Suen G.	Front Microbiol	10.3389/fmicb.2017.01553	2017
	Rumen microbial community composition varies with diet and host, but a core microbiome is found across a wide geographical range.	Henderson G, Cox F, Ganesh S, Jonker A, Young W, Global Rumen Census Collaborators, Janssen PH.	Sci Rep	10.1038/srep14567	2015
Genetics	Extensive Inter-Domain Lateral Gene Transfer in the Evolution of the Human Commensal Methanosphaera stadtmanae.	Lurie-Weinberger MN, Peeri M, Tuller T, Gophna U.	Front Genet	10.3389/fgene.2012.00182	2012
Metabolism	Syntrophic association of a butyrate-degrading bacterium and methanosarcina enriched from bovine rumen fluid.	McInerney MJ, Mackie RI, Bryant MP.	Appl Environ Microbiol	10.1128/aem.41.3.826-828.1981	1981
Pathogenicity	Effects of essential oils on methane production and fermentation by, and abundance and diversity of, rumen microbial populations.	Patra AK, Yu Z.	Appl Environ Microbiol	10.1128/aem.00309-12	2012
	Chromosome segregation in Archaea mediated by a hybrid DNA partition machine.	Kalliomaa-Sanford AK, Rodriguez-Castaneda FA, McLeod BN, Latorre-Rosello V, Smith JH, Reimann J, Albers SV, Barilla D.	Proc Natl Acad Sci U S A	10.1073/pnas.1113384109	2012
Pathogenicity	Review on Mycotoxin Issues in Ruminants: Occurrence in Forages, Effects of Mycotoxin Ingestion on Health Status and Animal Performance and Practical Strategies to Counteract Their Negative Effects.	Gallo A, Giuberti G, Frisvad JC, Bertuzzi T, Nielsen KF.	Toxins (Basel)	10.3390/toxins7083057	2015
Metabolism	Hydrogen formation and its regulation in Ruminococcus albus: involvement of an electron-bifurcating [FeFe]-hydrogenase, of a non-electron-bifurcating [FeFe]-hydrogenase, and of a putative hydrogen-sensing [FeFe]-hydrogenase.	Zheng Y, Kahnt J, Kwon IH, Mackie RI, Thauer RK.	J Bacteriol	10.1128/jb.02070-14	2014
	An Integrated Multi-Omics Approach Reveals the Effects of Supplementing Grass or Grass Hay with Vitamin E on the Rumen Microbiome and Its Function.	Belanche A, Kingston-Smith AH, Newbold CJ.	Front Microbiol	10.3389/fmicb.2016.00905	2016
Phylogeny	A Structural and Functional Elucidation of the Rumen Microbiome Influenced by Various Diets and Microenvironments.	Deusch S, Camarinha-Silva A, Conrad J, Beifuss U, Rodehutscord M, Seifert J.	Front Microbiol	10.3389/fmicb.2017.01605	2017
	Methanogens: biochemical background and biotechnological applications.	Enzmann F, Mayer F, Rother M, Holtmann D.	AMB Express	10.1186/s13568-017-0531-x	2018
Phylogeny	Phylogenetic comparison of the methanogenic communities from an acidic, oligotrophic fen and an anaerobic digester treating municipal wastewater sludge.	Steinberg LM, Regan JM.	Appl Environ Microbiol	10.1128/aem.00553-08	2008
Metabolism	Targeting methanopterin biosynthesis to inhibit methanogenesis.	Dumitru R, Palencia H, Schroeder SD, DeMontigny BA, Takacs JM, Rasche ME, Miner JL, Ragsdale SW.	Appl Environ Microbiol	10.1128/aem.69.12.7236-7241.2003	2003
Metabolism	Rapidly growing rumen methanogenic organism that synthesizes coenzyme M and has a high affinity for formate.	Lovley DR, Greening RC, Ferry JG.	Appl Environ Microbiol	10.1128/aem.48.1.81-87.1984	1984
Enzymology	Identification and quantification of archaea involved in primary endodontic infections.	Vianna ME, Conrads G, Gomes BP, Horz HP.	J Clin Microbiol	10.1128/jcm.44.4.1274-1282.2006	2006
	Methanogenic Archaea and human periodontal disease.	Lepp PW, Brinig MM, Ouverney CC, Palm K, Armitage GC, Relman DA.	Proc Natl Acad Sci U S A	10.1073/pnas.0308766101	2004
	Development of a swine-specific fecal pollution marker based on host differences in methanogen mcrA genes.	Ufnar JA, Ufnar DF, Wang SY, Ellender RD.	Appl Environ Microbiol	10.1128/aem.00319-07	2007
	Purine biosynthesis in archaea: variations on a theme.	Brown AM, Hoopes SL, White RH, Sarisky CA.	Biol Direct	10.1186/1745-6150-6-63	2011
Metabolism	Getting a handle on the role of coenzyme M in alkene metabolism.	Krishnakumar AM, Sliwa D, Endrizzi JA, Boyd ES, Ensign SA, Peters JW.	Microbiol Mol Biol Rev	10.1128/mmbr.00005-08	2008
Metabolism	New approach to the cultivation of methanogenic bacteria: 2-mercaptoethanesulfonic acid (HS-CoM)-dependent growth of Methanobacterium ruminantium in a pressureized atmosphere.	Balch WE, Wolfe RS.	Appl Environ Microbiol	10.1128/aem.32.6.781-791.1976	1976
Metabolism	Transport of coenzyme M (2-mercaptoethanesulfonic acid) in Methanobacterium ruminantium.	Balch WE, Wolfe RS.	J Bacteriol	10.1128/jb.137.1.264-273.1979	1979
Biotechnology	The Ability of Hop Extracts to Reduce the Methane Production of Methanobrevibacter ruminantium.	Blaxland JA, Watkins AJ, Baillie LWJ	Archaea	10.1155/2021/5510063	2021
Transcriptome	The transcriptome response of the ruminal methanogen Methanobrevibacter ruminantium strain M1 to the inhibitor lauric acid.	Zhou X, Stevens MJA, Neuenschwander S, Schwarm A, Kreuzer M, Bratus-Neuenschwander A, Zeitz JO	BMC Res Notes	10.1186/s13104-018-3242-8	2018
Pathogenicity	The effect of saturated fatty acids on methanogenesis and cell viability of Methanobrevibacter ruminantium.	Zhou X, Meile L, Kreuzer M, Zeitz JO	Archaea	10.1155/2013/106916	2013
	Anaerobic flora, Selenomonas ruminis sp. nov., and the bacteriocinogenic Ligilactobacillus salivarius strain MP3 from crossbred-lactating goats.	Poothong S, Tanasupawat S, Chanpongsang S, Kingkaew E, Nuengjamnong C.	Sci Rep	10.1038/s41598-024-54686-6	2024

References

#547	Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 1093
#20215	Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 )
#66792	Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) .
#66794	Antje Chang, Lisa Jeske, Sandra Ulbrich, Julia Hofmann, Julia Koblitz, Ida Schomburg, Meina Neumann-Schaal, Dieter Jahn, Dietmar Schomburg: BRENDA, the ELIXIR core data resource in 2021: new developments and updates. Nucleic Acids Res. 49: D498 - D508 2020 ( DOI 10.1093/nar/gkaa1025 , PubMed 33211880 )
#67770	Japan Collection of Microorganism (JCM) ; Curators of the JCM;
#69479	João F Matias Rodrigues, Janko Tackmann,Gregor Rot, Thomas SB Schmidt, Lukas Malfertheiner, Mihai Danaila,Marija Dmitrijeva, Daniela Gaio, Nicolas Näpflin and Christian von Mering. University of Zurich.: MicrobeAtlas 1.0 beta .
#125438	Julia Koblitz, Lorenz Christian Reimer, Rüdiger Pukall, Jörg Overmann: Predicting bacterial phenotypic traits through improved machine learning using high-quality, curated datasets. 2024 ( DOI 10.1101/2024.08.12.607695 )
#125439	Philipp Münch, René Mreches, Martin Binder, Hüseyin Anil Gündüz, Xiao-Yin To, Alice McHardy: deepG: Deep Learning for Genome Sequence Data. R package version 0.3.1 .
#126262	A. Lissin, I. Schober, J. F. Witte, H. Lüken, A. Podstawka, J. Koblitz, B. Bunk, P. Dawyndt, P. Vandamme, P. de Vos, J. Overmann, L. C. Reimer: StrainInfo—the central database for linked microbial strain identifiers. ( DOI 10.1093/database/baaf059 )

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Methanobrevibacter ruminantium (DSM 1093, ATCC 35063, JCM 13430)

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