Methanobacterium thermautotrophicum (DSM 1053, ATCC 29096, JCM 10044)

Name: Methanobacterium thermautotrophicum (DSM 1053, ATCC 29096, JCM 10044)
Creator: BacDive
License: http://creativecommons.org/licenses/by/4.0/

BacDive ID 6882

Type strain

Strain Designation Delta H, DeltaH

Culture col. no. DSM 1053 ATCC 29096 JCM 10044 NBRC 100330 Delta H 3 more

NCBI tax ID(s) 145262

Special Collections DSMZ JCM

History <- J. G. Zeikus, University of Illinois, Urbana, USA; DeltaH <- J. G. Zeikus {1971} DSM 1053 <-- J. G. Zeikus ΔH.

Links

Methanobacterium thermautotrophicum Delta H is an anaerobe archaeon that was isolated from sewage sludge.

anaerobe genome sequence 16S sequence Archaea

Name and taxonomic classification

SI-ID 47306

DSM 1053,ATCC 29096,JCM 10044,VKM B-1908,NBRC 100330

@ref 20215

Last LPSN update 2026-02-09 11:19:20

Domain Archaea

Phylum Methanobacteriota

Class Methanobacteria

Order Methanobacteriales

Family Methanobacteriaceae

Genus Methanobacterium

Species Methanobacterium thermautotrophicum

Full scientific name Methanobacterium thermautotrophicum corrig. Zeikus and Wolfe 1972 (Approved Lists 1980)

Synonyms (6)

Methanobacterium thermoautotrophicum
Methanothermobacter thermautotrophicus
Methanobacterium thermalcaliphilum
Methanobacterium thermoautotrophicus
Methanobacterium thermoalcaliphilum
Methanobacterium thermoformicicum

Morphology

Culture and growth conditions

Culture medium

@ref	Name	Growth	Medium link	Composition
387	MODIFIED METHANOBACTERIUM MEDIUM (DSMZ Medium 1523)		Medium recipe at MediaDive	Name: MODIFIED METHANOBACTERIUM MEDIUM (DSMZ Medium 1523) Composition: Brain heart infusion 5.98802 g/l Proteose peptone 5.98802 g/l NaHCO3 3.99202 g/l Yeast extract 1.99601 g/l Na-formate 1.99601 g/l Na-acetate 0.998004 g/l Na2S x 9 H2O 0.499002 g/l KH2PO4 0.499002 g/l L-Cysteine HCl x H2O 0.499002 g/l MgSO4 x 7 H2O 0.399202 g/l NH4Cl 0.399202 g/l NaCl 0.399202 g/l CaCl2 x 2 H2O 0.0499002 g/l HCl 0.00249501 g/l FeCl2 x 4 H2O 0.00149701 g/l Sodium resazurin 0.000499002 g/l Pyridoxine hydrochloride 0.000299401 g/l Thiamine-HCl x 2 H2O 0.000199601 g/l Nicotinic acid 0.000199601 g/l CoCl2 x 6 H2O 0.000189621 g/l Calcium pantothenate 9.98004e-05 g/l Vitamin B12 9.98004e-05 g/l MnCl2 x 4 H2O 9.98004e-05 g/l p-Aminobenzoic acid 7.98403e-05 g/l ZnCl2 6.98603e-05 g/l Na2MoO4 x 2 H2O 3.59281e-05 g/l NiCl2 x 6 H2O 2.39521e-05 g/l D-(+)-biotin 1.99601e-05 g/l H3BO3 5.98802e-06 g/l CuCl2 x 2 H2O 1.99601e-06 g/l Distilled water
387	METHANOBACTERIUM MEDIUM (DSMZ Medium 119)		Medium recipe at MediaDive	Name: METHANOBACTERIUM MEDIUM (DSMZ Medium 119) Composition: NaHCO3 3.98804 g/l Na-formate 1.99402 g/l Na-acetate 0.997009 g/l Na2S x 9 H2O 0.498504 g/l L-Cysteine HCl x H2O 0.498504 g/l KH2PO4 0.498504 g/l NH4Cl 0.398804 g/l NaCl 0.398804 g/l MgSO4 x 7 H2O 0.398804 g/l Yeast extract 0.199402 g/l CaCl2 x 2 H2O 0.0498504 g/l HCl 0.00249252 g/l FeSO4 x 7 H2O 0.00199402 g/l FeCl2 x 4 H2O 0.00149551 g/l Sodium resazurin 0.000498504 g/l CoCl2 x 6 H2O 0.000189432 g/l MnCl2 x 4 H2O 9.97009e-05 g/l ZnCl2 6.97906e-05 g/l Na2MoO4 x 2 H2O 3.58923e-05 g/l NiCl2 x 6 H2O 2.39282e-05 g/l H3BO3 5.98205e-06 g/l CuCl2 x 2 H2O 1.99402e-06 g/l Isobutyric acid DL-2-Methylbutyric acid Valeric acid Isovaleric acid H2SO4 Sludge Distilled water

Culture temp

@ref	Growth	Type	Temperature (°C)
387	positive	growth	65
67770	positive	growth	65

Physiology and metabolism

Oxygen tolerance

@ref	Oxygen tolerance	Confidence
387	anaerobe
125439	obligate anaerobe	99.8

Spore formation

@ref	Spore formation	Confidence
125438		91.493

Compound production

@ref	Compound
387	7,8 didemethyl-8-hydroxy-5-deazariboflavin
387	coenzyme F₄₂₀

Isolation, sampling and environmental information

Isolation source categories

Cat1	Cat2	Cat3
#Engineered	#Waste	#Sewage sludge

Isolation

@ref	Sample type	Geographic location	Country	Country ISO 3 Code	Continent
387	sewage sludge	Illinois, Urbana	USA	USA	North America
67770	Anaerobic sewage-sludge

Interaction and safety

Risk assessment

@ref	Biosafety level	Biosafety level comment
387	1	Risk group (German classification) According to TRBA 466

Sequence information

Genome sequences

@ref	Description	Assembly level	INSDC accession	BV-BRC accession	IMG accession	NCBI tax ID	Score
66792	ASM864v1 assembly for Methanothermobacter thermautotrophicus str. Delta H	complete	GCA_000008645	187420.15	638154510	187420	98.73
66792	ASM2755490v1 assembly for Methanothermobacter thermautotrophicus Delta H	complete	GCA_027554905		8049250981	145262	98.23

16S sequences

@ref	Description	Accession	Length	Database	NCBI tax ID
67770	M.thermoautotrophicum (DELTA H) gene for 16S rRNA	X68720	1334		145262
387	Methanothermobacter thermautotrophicus strain delta H 16S ribosomal RNA gene, partial sequence	AY196660	1265		145262

GC content

@ref	GC-content (mol%)	Method
387	49.7
387	48.6
67770	52	Buoyant density centrifugation (BD)
67770	49.7	Buoyant density centrifugation (BD)
67770	50.7	thermal denaturation, midpoint method (Tm)

Genome-based predictions

Predictions

Predictions from Deep Learning for Genome Sequence Data. R package version 0.3.1 based on: Methanothermobacter thermautotrophicus str. Delta H
NCBI: GCA_000008645

@ref	Trait	Model	Prediction	Confidence in %	In training data
125439	spore_formation	BacteriaNetⓘ	no	83.20	no
125439	motility	BacteriaNetⓘ	no	67.60	no
125439	gram_stain	BacteriaNetⓘ	variable	65.20	no
125439	oxygen_tolerance	BacteriaNetⓘ	obligate anaerobe	99.80	no

Predictions from bacterial phenotypic traits through improved machine learning using high-quality, curated datasets based on: Methanothermobacter thermautotrophicus str. Delta H Delta H
NCBI: GCA_000008645.1

@ref	Trait	Model	Prediction	Confidence in %	In training data
125438	gram-positive	gram-positiveⓘ	no	52.48	no
125438	anaerobic	anaerobicⓘ	yes	89.28	yes
125438	aerobic	aerobicⓘ	no	89.18	no
125438	spore-forming	spore-formingⓘ	no	91.49	no
125438	thermophilic	thermophileⓘ	yes	64.79	no
125438	flagellated	motile2+ⓘ	no	88.50	no

Literature

Topic	Title	Authors	Journal	DOI	Year
Biotechnology	A development study for liquid- and vapor-fed anode zero-gap bioelectrolysis cells.	Rohbohm N, Angenent LT.	iScience	10.1016/j.isci.2025.112959	2025
	Phenyl Acid Induced Inhibition of Methanogenesis in CO₂ Reducing Organisms.	Wunderer M, Unterkircher M, Schmidhofer A, Prem EM, Wagner AO.	Environ Microbiol Rep	10.1111/1758-2229.70082	2025
	An integrated systems biology approach reveals differences in formate metabolism in the genus Methanothermobacter.	Casini I, McCubbin T, Esquivel-Elizondo S, Luque GG, Evseeva D, Fink C, Beblawy S, Youngblut ND, Aristilde L, Huson DH, Drager A, Ley RE, Marcellin E, Angenent LT, Molitor B.	iScience	10.1016/j.isci.2023.108016	2023
Enzymology	Comprehensive mutagenesis to identify amino acid residues contributing to the difference in thermostability between two originally thermostable ancestral proteins.	Akanuma S, Yamaguchi M, Yamagishi A.	PLoS One	10.1371/journal.pone.0258821	2021
Genetics	Complete genome sequence of Methanothermobacter marburgensis, a methanoarchaeon model organism.	Liesegang H, Kaster AK, Wiezer A, Goenrich M, Wollherr A, Seedorf H, Gottschalk G, Thauer RK.	J Bacteriol	10.1128/jb.00844-10	2010
	Large-Scale Molecular Evolutionary Analysis Uncovers a Variety of Polynucleotide Kinase Clp1 Family Proteins in the Three Domains of Life.	Saito M, Sato A, Nagata S, Tamaki S, Tomita M, Suzuki H, Kanai A.	Genome Biol Evol	10.1093/gbe/evz195	2019
Pathogenicity	Carbon dioxide concentration dictates alternative methanogenic pathways in oil reservoirs.	Mayumi D, Dolfing J, Sakata S, Maeda H, Miyagawa Y, Ikarashi M, Tamaki H, Takeuchi M, Nakatsu CH, Kamagata Y.	Nat Commun	10.1038/ncomms2998	2013
Metabolism	A novel biosynthetic pathway of archaetidyl-myo-inositol via archaetidyl-myo-inositol phosphate from CDP-archaeol and D-glucose 6-phosphate in methanoarchaeon Methanothermobacter thermautotrophicus cells.	Morii H, Kiyonari S, Ishino Y, Koga Y.	J Biol Chem	10.1074/jbc.m109.034652	2009
Metabolism	In vitro biosynthesis of ether-type glycolipids in the methanoarchaeon Methanothermobacter thermautotrophicus.	Morii H, Eguchi T, Koga Y.	J Bacteriol	10.1128/jb.01875-06	2007
Phylogeny	Vertebrate host phylogeny influences gut archaeal diversity.	Youngblut ND, Reischer GH, Dauser S, Maisch S, Walzer C, Stalder G, Farnleitner AH, Ley RE.	Nat Microbiol	10.1038/s41564-021-00980-2	2021
Metabolism	Biochemical Characterisation of Phage Pseudomurein Endoisopeptidases PeiW and PeiP Using Synthetic Peptides.	Schofield LR, Beattie AK, Tootill CM, Dey D, Ronimus RS.	Archaea	10.1155/2015/828693	2015
Metabolism	Coupling of Methanothermobacter thermautotrophicus methane formation and growth in fed-batch and continuous cultures under different H2 gassing regimens.	de Poorter LM, Geerts WJ, Keltjens JT.	Appl Environ Microbiol	10.1128/aem.01885-06	2007
Metabolism	The Methanothermobacter thermautotrophicus ExoIII homologue Mth212 is a DNA uridine endonuclease.	Georg J, Schomacher L, Chong JP, Majernik AI, Raabe M, Urlaub H, Muller S, Ciirdaeva E, Kramer W, Fritz HJ.	Nucleic Acids Res	10.1093/nar/gkl604	2006
Genetics	Cell cycle characteristics of crenarchaeota: unity among diversity.	Lundgren M, Malandrin L, Eriksson S, Huber H, Bernander R.	J Bacteriol	10.1128/jb.00330-08	2008
Enzymology	CDP-2,3-Di-O-geranylgeranyl-sn-glycerol:L-serine O-archaetidyltransferase (archaetidylserine synthase) in the methanogenic archaeon Methanothermobacter thermautotrophicus.	Morii H, Koga Y.	J Bacteriol	10.1128/jb.185.4.1181-1189.2003	2003
Phylogeny	In situ detection, isolation, and physiological properties of a thin filamentous microorganism abundant in methanogenic granular sludges: a novel isolate affiliated with a clone cluster, the green non-sulfur bacteria, subdivision I.	Sekiguchi Y, Takahashi H, Kamagata Y, Ohashi A, Harada H.	Appl Environ Microbiol	10.1128/aem.67.12.5740-5749.2001	2001
Metabolism	Helix-hairpin-helix protein MJ1434 from Methanocaldococcus jannaschii and EndoIV homologue TTC0482 from Thermus thermophilus HB27 do not process DNA uracil residues.	Schomacher L, Smolorz S, Ciirdaeva E, Ber S, Kramer W, Fritz HJ.	Nucleic Acids Res	10.1093/nar/gkq270	2010
Transcriptome	Enzyme Function Initiative-Enzyme Similarity Tool (EFI-EST): A web tool for generating protein sequence similarity networks.	Gerlt JA, Bouvier JT, Davidson DB, Imker HJ, Sadkhin B, Slater DR, Whalen KL.	Biochim Biophys Acta	10.1016/j.bbapap.2015.04.015	2015
Metabolism	Reconstruction and regulation of the central catabolic pathway in the thermophilic propionate-oxidizing syntroph Pelotomaculum thermopropionicum.	Kosaka T, Uchiyama T, Ishii S, Enoki M, Imachi H, Kamagata Y, Ohashi A, Harada H, Ikenaga H, Watanabe K.	J Bacteriol	10.1128/jb.188.1.202-210.2006	2006
Metabolism	Non-sulfate-reducing, syntrophic bacteria affiliated with desulfotomaculum cluster I are widely distributed in methanogenic environments.	Imachi H, Sekiguchi Y, Kamagata Y, Loy A, Qiu YL, Hugenholtz P, Kimura N, Wagner M, Ohashi A, Harada H.	Appl Environ Microbiol	10.1128/aem.72.3.2080-2091.2006	2006
Metabolism	A novel nuclease-ATPase (Nar71) from archaea is part of a proposed thermophilic DNA repair system.	Guy CP, Majernik AI, Chong JP, Bolt EL.	Nucleic Acids Res	10.1093/nar/gkh960	2004
	Light sensitivity of methanogenic archaebacteria.	Olson KD, McMahon CW, Wolfe RS.	Appl Environ Microbiol	10.1128/aem.57.9.2683-2686.1991	1991
Phylogeny	Diversity, localization, and physiological properties of filamentous microbes belonging to Chloroflexi subphylum I in mesophilic and thermophilic methanogenic sludge granules.	Yamada T, Sekiguchi Y, Imachi H, Kamagata Y, Ohashi A, Harada H.	Appl Environ Microbiol	10.1128/aem.71.11.7493-7503.2005	2005
Enzymology	Minor changes largely restore catalytic activity of archaeal RNase P RNA from Methanothermobacter thermoautotrophicus.	Li D, Willkomm DK, Hartmann RK.	Nucleic Acids Res	10.1093/nar/gkn915	2009
Metabolism	Cultivation and in situ detection of a thermophilic bacterium capable of oxidizing propionate in syntrophic association with hydrogenotrophic methanogens in a thermophilic methanogenic granular sludge.	Imachi H, Sekiguchi Y, Kamagata Y, Ohashi A, Harada H.	Appl Environ Microbiol	10.1128/aem.66.8.3608-3615.2000	2000
Enzymology	Comparison of vertical distributions of prokaryotic assemblages in the anoxic Cariaco Basin and Black Sea by use of fluorescence in situ hybridization.	Lin X, Wakeham SG, Putnam IF, Astor YM, Scranton MI, Chistoserdov AY, Taylor GT.	Appl Environ Microbiol	10.1128/aem.72.4.2679-2690.2006	2006
	Immunocytochemical localization of component C of the methylreductase system in Methanococcus voltae and Methanobacterium thermoautotrophicum.	Ossmer R, Mund T, Hartzell PL, Konheiser U, Kohring GW, Klein A, Wolfe RS, Gottschalk G, Mayer F.	Proc Natl Acad Sci U S A	10.1073/pnas.83.16.5789	1986
Metabolism	Activation of formylmethanofuran synthesis in cell extracts of Methanobacterium thermoautotrophicum.	Bobik TA, Wolfe RS.	J Bacteriol	10.1128/jb.171.3.1423-1427.1989	1989
Metabolism	Hydrolysis and reduction of factor 390 by cell extracts of Methanobacterium thermoautotrophicum (strain delta H).	Kengen SW, von den Hoff HW, Keltjens JT, van der Drift C, Vogels GD.	J Bacteriol	10.1128/jb.173.7.2283-2288.1991	1991
	Physical map of the Methanobacterium thermoautotrophicum Marburg chromosome.	Stettler R, Leisinger T.	J Bacteriol	10.1128/jb.174.22.7227-7234.1992	1992
Metabolism	Organization and growth phase-dependent transcription of methane genes in two regions of the Methanobacterium thermoautotrophicum genome.	Nolling J, Pihl TD, Vriesema A, Reeve JN.	J Bacteriol	10.1128/jb.177.9.2460-2468.1995	1995
Phylogeny	A new class of DNA photolyases present in various organisms including aplacental mammals.	Yasui A, Eker AP, Yasuhira S, Yajima H, Kobayashi T, Takao M, Oikawa A.	EMBO J	10.1002/j.1460-2075.1994.tb06961.x	1994
Enzymology	Purification and characterization of the reduced-nicotinamide-dependent 2,2'-dithiodiethanesulfonate reductase from Methanobacterium thermoautotrophicum delta H.	Smith SG, Rouviere PE.	J Bacteriol	10.1128/jb.172.11.6435-6441.1990	1990
Enzymology	Purification and properties of 5,10-methenyltetrahydromethanopterin cyclohydrolase from Methanosarcina barkeri.	te Brommelstroet BW, Hensgens CM, Geerts WJ, Keltjens JT, van der Drift C, Vogels GD.	J Bacteriol	10.1128/jb.172.2.564-571.1990	1990
Metabolism	Methyl-coenzyme M reductase of Methanobacterium thermoautotrophicum delta H catalyzes the reductive dechlorination of 1,2-dichloroethane to ethylene and chloroethane.	Holliger C, Kengen SW, Schraa G, Stams AJ, Zehnder AJ.	J Bacteriol	10.1128/jb.174.13.4435-4443.1992	1992
Metabolism	Assimilatory reduction of sulfate and sulfite by methanogenic bacteria.	Daniels L, Belay N, Rajagopal BS.	Appl Environ Microbiol	10.1128/aem.51.4.703-709.1986	1986
	Inhibition of Rumen Methanogens by a Novel Archaeal Lytic Enzyme Displayed on Tailored Bionanoparticles.	Altermann E, Schofield LR, Ronimus RS, Beatty AK, Reilly K.	Front Microbiol	10.3389/fmicb.2018.02378	2018
Enzymology	Characterization of thermophilic archaeal isopentenyl phosphate kinases.	Chen M, Poulter CD.	Biochemistry	10.1021/bi9017957	2010
Metabolism	Requirement of the nickel tetrapyrrole F430 for in vitro methanogenesis: reconstitution of methylreductase component C from its dissociated subunits.	Hartzell PL, Wolfe RS.	Proc Natl Acad Sci U S A	10.1073/pnas.83.18.6726	1986
Metabolism	Formate auxotroph of Methanobacterium thermoautotrophicum Marburg.	Tanner RS, McInerney MJ, Nagle DP.	J Bacteriol	10.1128/jb.171.12.6534-6538.1989	1989
Metabolism	Structural modifications and kinetic studies of the substrates involved in the final step of methane formation in Methanobacterium thermoautotrophicum.	Olson KD, Chmurkowska-Cichowlas L, McMahon CW, Wolfe RS.	J Bacteriol	10.1128/jb.174.3.1007-1012.1992	1992
Enzymology	Structure of component B (7-mercaptoheptanoylthreonine phosphate) of the methylcoenzyme M methylreductase system of Methanobacterium thermoautotrophicum.	Noll KM, Rinehart KL, Tanner RS, Wolfe RS.	Proc Natl Acad Sci U S A	10.1073/pnas.83.12.4238	1986
Metabolism	Levels of cyclic-2,3-diphosphoglycerate in Methanobacterium thermoautotrophicum during phosphate limitation.	Seely RJ, Fahrney DE.	J Bacteriol	10.1128/jb.160.1.50-54.1984	1984
Enzymology	Component A of the methyl coenzyme M methylreductase system of Methanobacterium: resolution into four components.	Nagle DP, Wolfe RS.	Proc Natl Acad Sci U S A	10.1073/pnas.80.8.2151	1983
	Role of organic acid-degrading bacteria in a microbial methanation system using a subterranean microbial community.	Kawano M, Ikeura K, Taniguchi H, Terao M, Ichikawa K, Higashi T, Futamata H, Kimura H.	World J Microbiol Biotechnol	10.1007/s11274-025-04496-3	2025
	Functional Group Distribution of the Carrier Surface Influences Adhesion of Methanothermobacter thermautotrophicus.	Umetsu M, Sunouchi T, Fukuda Y, Takahashi H, Tada C.	Archaea	10.1155/2020/9432803	2020
	Repurposing branched chain amino acid aminotransferase in the chemoenzymatic synthesis of azacyclic noncanonical amino acids.	Chao TH, Renata H.	Methods Enzymol	10.1016/bs.mie.2025.08.019	2025
	Bacterial/archaeal protein-only RNase P: complementation in Escherichia coli uncovers coevolution of protein-only RNase P and precursor tRNA structures in Aquifex aeolicus.	Davydov S, Waber NB, Gossringer M, Klemm P, Rennar I, Lechner M, Hartmann RK.	RNA	10.1261/rna.080492.125	2025
	Advances in production related petroleum microbiology.	Mahajan S, Tyagi A, Prajapat G, Agrawal A.	Adv Appl Microbiol	10.1016/bs.aambs.2025.04.001	2025
	Methanothermobacter thermautotrophicus and Alternative Methanogens: Archaea-Based Production.	Muhling L, Baur T, Molitor B.	Adv Biochem Eng Biotechnol	10.1007/10_2024_270	2025
Enzymology	Convergent Evolution of Coenzyme Metabolism in Methanosarcina mazei: Insights Into Primitive Life and Metabolic Adaptations.	Saranya SV, Chellapandi P.	J Basic Microbiol	10.1002/jobm.70015	2025
	Advances in production related petroleum microbiology	Mahajan S, Tyagi A, Prajapat G, Agrawal A.	Advances in Applied Microbiology.		2025
	Improving photosynthetic efficiency of rice via over-expressing a ferredoxin-like protein gene from Methanothermobacter thermautotrophicus.	Yan X, Si F, Zhu D, Chen Q, Hu Z, Wang T, Ying S, Tang Y, Yang J, Ding X, Li Y, Liu Y, Wang Z, Peng X.	Physiol Plant	10.1111/ppl.14571	2024
	Dynamically Interacting Protein Networks Provide a Mechanism to Overcome the Enormous Intrinsic Barrier to Orotidine 5'-Monophosphate Decarboxylation.	Dubey P, Somani A, Lin J, Iavarone AT, Klinman JP.	ACS Cent Sci	10.1021/acscentsci.5c00590	2025
	Structural characterisation of methanogen pseudomurein cell wall peptide ligases homologous to bacterial MurE/F murein peptide ligases.	Subedi BP, Schofield LR, Carbone V, Wolf M, Martin WF, Ronimus RS, Sutherland-Smith AJ.	Microbiology (Reading)	10.1099/mic.0.001235	2022
	In-situ biogas upgrading assisted by bioaugmentation with hydrogenotrophic methanogens during mesophilic and thermophilic co-digestion.	Palu M, Peprah M, Tsapekos P, Kougias P, Campanaro S, Angelidaki I, Treu L.	Bioresour Technol	10.1016/j.biortech.2022.126754	2022
	Green Synthesis of Vanadium Dioxide Nanoparticles by Shewanella sp. Strain HN-41.	Ko Y, Kang S, Yang Y, Lee J, Hur HG.	J Microbiol Biotechnol	10.4014/jmb.2502.02051	2025
	Comprehensive evaluation of different strategies to recover methanogenic performance in ammonia-stressed reactors.	Yan M, Zhu X, Treu L, Ravenni G, Campanaro S, Goonesekera EM, Ferrigno R, Jacobsen CS, Zervas A, Angelidaki I, Fotidis IA.	Bioresour Technol	10.1016/j.biortech.2021.125329	2021
Biotechnology	Markerless mutagenesis enables isoleucine biosynthesis solely from threonine in Methanothermobacter marburgensis.	Klein M, Hilts AS, Fennessy RT, Trattnig N, Stehrer-Polasek T, Rittmann SK-MR, Fink C.	Microbiol Spectr	10.1128/spectrum.03068-24	2025
Enzymology	Development of a rapid and highly accurate method for ¹³C tracer-based metabolomics and its application on a hydrogenotrophic methanogen.	Fukuyama Y, Shimamura S, Sakai S, Michimori Y, Sumida T, Chikaraishi Y, Atomi H, Nunoura T.	ISME Commun	10.1093/ismeco/ycad006	2024
Metabolism	Application of Acetyl-CoA synthetase from Methanothermobacter thermautotrophicus to non-native substrates.	Mouterde LMM, Stewart JD.	Enzyme Microb Technol	10.1016/j.enzmictec.2019.05.005	2019
	Impact of trace metal supplementation on anaerobic biological methanation under hydrogen and carbon dioxide starvation.	Ghiotto G, De Bernardini N, Orellana E, Fiorito G, Cenci L, Kougias PG, Campanaro S, Treu L.	NPJ Biofilms Microbiomes	10.1038/s41522-025-00649-2	2025
Enzymology	Thermostable Enzyme Variants in the Lower Mevalonate Pathway Improve Isoprenoid Production by Cell-Free Biocatalysis.	Sarnik SA, Martinsen MR, Korman TP, Schwartz DK, Kaar JL, Bomble YJ.	ACS Sustain Chem Eng	10.1021/acssuschemeng.5c03763	2025
	Archaeal Hel308 suppresses recombination through a catalytic switch that controls DNA annealing.	Lever RJ, Simmons E, Gamble-Milner R, Buckley RJ, Harrison C, Parkes AJ, Mitchell L, Gausden JA, Skulj S, Bertosa B, Bolt EL, Allers T.	Nucleic Acids Res	10.1093/nar/gkad572	2023
Metabolism	Meta-omics based analyses of microbiome involved in biomethanation of rice straw in a thermophilic anaerobic bioreactor under optimized conditions.	Pore SD, Engineer A, Dagar SS, Dhakephalkar PK.	Bioresour Technol	10.1016/j.biortech.2019.01.099	2019
	The Roles of Coenzyme A Binding Pocket Residues in Short and Medium Chain Acyl-CoA Synthetases.	Meng Y, Ingram-Smith C, Ahmed O, Smith K.	Life (Basel)	10.3390/life13081643	2023
	Over-expression of a protein disulfide isomerase gene from Methanothermobacter thermautotrophicus, enhances heat stress tolerance in rice.	Wang X, Chen J, Liu C, Luo J, Yan X, Aihua Ai, Cai Y, Xie H, Ding X, Peng X.	Gene	10.1016/j.gene.2018.10.064	2019
	One-pot chemoenzymatic syntheses of non-canonical amino acids.	Chao TH, Wu X, Renata H.	J Ind Microbiol Biotechnol	10.1093/jimb/kuae005	2024
Genetics	Remote Homology Detection Identifies a Eukaryotic RPA DBD-C-like DNA Binding Domain as a Conserved Feature of Archaeal Rpa1-Like Proteins.	MacNeill SA.	Front Mol Biosci	10.3389/fmolb.2021.675229	2021
	Nitrogenase Cofactor Maturase NifB Isolated from Transgenic Rice is Active in FeMo-co Synthesis.	He W, Buren S, Baysal C, Jiang X, Capell T, Christou P, Rubio LM.	ACS Synth Biol	10.1021/acssynbio.2c00194	2022
Phylogeny	Human Milk Archaea Associated with Neonatal Gut Colonization and Its Co-Occurrence with Bacteria.	Salas-Lopez M, Velez-Ixta JM, Rojas-Guerrero DL, Pina-Escobedo A, Hernandez-Hernandez JM, Rangel-Calvillo MN, Perez-Cruz C, Corona-Cervantes K, Juarez-Castelan CJ, Garcia-Mena J.	Microorganisms	10.3390/microorganisms13010085	2025
	Engineering Escherichia coli via introduction of the isopentenol utilization pathway to effectively produce geranyllinalool.	Chang J, Wei X, Liu D, Li Q, Li C, Zhao J, Cheng L, Wang G.	Microb Cell Fact	10.1186/s12934-024-02563-2	2024
	Two-year microbial adaptation during hydrogen-mediated biogas upgrading process in a serial reactor configuration.	Treu L, Kougias PG, de Diego-Diaz B, Campanaro S, Bassani I, Fernandez-Rodriguez J, Angelidaki I.	Bioresour Technol	10.1016/j.biortech.2018.05.070	2018
Genetics	A large-scale genomically predicted protein mass database enables rapid and broad-spectrum identification of bacterial and archaeal isolates by mass spectrometry.	Sekiguchi Y, Teramoto K, Tourlousse DM, Ohashi A, Hamajima M, Miura D, Yamada Y, Iwamoto S, Tanaka K.	Genome Biol	10.1186/s13059-023-03096-4	2023
Genetics	Releasing the "GENI": integrating authentic microbial genomics research into the classroom through GENI-ACT.	Moitra K.	FEMS Microbiol Lett	10.1093/femsle/fnx215	2017
Enzymology	Hexamerization of Geranylgeranylglyceryl Phosphate Synthase Ensures Structural Integrity and Catalytic Activity at High Temperatures.	Linde M, Heyn K, Merkl R, Sterner R, Babinger P.	Biochemistry	10.1021/acs.biochem.7b01284	2018
Stress	Performance and microbial community of hydrogenotrophic methanogenesis under thermophilic and extreme-thermophilic conditions.	Dong N, Bu F, Zhou Q, Khanal SK, Xie L.	Bioresour Technol	10.1016/j.biortech.2018.05.105	2018
	Evaluation of process performance, energy consumption and microbiota characterization in a ceramic membrane bioreactor for ex-situ biomethanation of H₂ and CO₂.	Alfaro N, Fdz-Polanco M, Fdz-Polanco F, Diaz I.	Bioresour Technol	10.1016/j.biortech.2018.02.087	2018
Enzymology	Carbon Monoxide Production during Bio-Waste Composting under Different Temperature and Aeration Regimes.	Sobieraj K, Stegenta-Dabrowska S, Zafiu C, Binner E, Bialowiec A.	Materials (Basel)	10.3390/ma16134551	2023
	Identification and characterization of archaeal pseudomurein biosynthesis genes through pangenomics.	Lupo V, Roomans C, Royen E, Ongena L, Jacquemin O, Mullender C, Kerff F, Baurain D.	mSystems	10.1128/msystems.01401-24	2025
Enzymology	An archaeal aminoacyl-tRNA synthetase complex for improved substrate quality control.	Crnkovic A, Cavuzic M, Godinic-Mikulcic V, Anderluh G, Weygand-Durasevic I, Gruic-Sovulj I.	Biochimie	10.1016/j.biochi.2017.12.006	2018
Metabolism	Comparative proteomic analysis of Methanothermobacter thermautotrophicus reveals methane formation from H₂ and CO₂ under different temperature conditions.	Liu C, Mao L, Zheng X, Yuan J, Hu B, Cai Y, Xie H, Peng X, Ding X.	Microbiologyopen	10.1002/mbo3.715	2019
Genetics	A Rapid, Sensitive, Low-Cost Assay for Detecting Hydrogenotrophic Methanogens in Anaerobic Digesters Using Loop-Mediated Isothermal Amplification.	Alessi AM, Tao B, Zhang W, Zhang Y, Heaven S, Banks CJ, Chong JPJ.	Microorganisms	10.3390/microorganisms8050740	2020
Genetics	Archaea Microbiome Dysregulated Genes and Pathways as Molecular Targets for Lung Adenocarcinoma and Squamous Cell Carcinoma.	Uzelac M, Li Y, Chakladar J, Li WT, Ongkeko WM.	Int J Mol Sci	10.3390/ijms231911566	2022
	Atomic Force Microscopy Investigation of the Interactions between the MCM Helicase and DNA.	Mohammed Khalid AA, Parisse P, Medagli B, Onesti S, Casalis L.	Materials (Basel)	10.3390/ma14030687	2021
	Ex-situ biogas upgrading and enhancement in different reactor systems.	Kougias PG, Treu L, Benavente DP, Boe K, Campanaro S, Angelidaki I.	Bioresour Technol	10.1016/j.biortech.2016.11.124	2017
Phylogeny	Optimization of hydrogen dispersion in thermophilic up-flow reactors for ex situ biogas upgrading.	Bassani I, Kougias PG, Treu L, Porte H, Campanaro S, Angelidaki I.	Bioresour Technol	10.1016/j.biortech.2017.03.055	2017
Metabolism	Effect of operating temperature on anaerobic digestion of the Brazilian waterweed Egeria densa and its microbial community.	Watanabe K, Koyama M, Ueda J, Ban S, Kurosawa N, Toda T.	Anaerobe	10.1016/j.anaerobe.2017.03.014	2017
	Structural Insights into the Rrp4 Subunit from the Crystal Structure of the Thermoplasma acidophilum Exosome	Park S, Kim H, Bang K, Han A, Shin B, Seo M, Kim S, Hwang K.	Biomolecules		2024
	Microbiological insight into various underground gas storages in Vienna Basin focusing on methanogenic Archaea.	Hanisakova N, Vitezova M, Vitez T, Kushkevych I, Kotrlova E, Novak D, Lochman J, Zavada R.	Front Microbiol	10.3389/fmicb.2023.1293506	2023
	Computational Network Inference for Bacterial Interactomics.	James K, Munoz-Munoz J.	mSystems	10.1128/msystems.01456-21	2022
Enzymology	The Characterization of Ancient Methanococcales Malate Dehydrogenases Reveals That Strong Thermal Stability Prevents Unfolding Under Intense gamma-Irradiation.	Madern D, Halgand F, Houee-Levin C, Dufour AB, Coquille S, Ansanay-Alex S, Sacquin-Mora S, Brochier-Armanet C.	Mol Biol Evol	10.1093/molbev/msae231	2024
	Biosynthesis of GMGT lipids by a radical SAM enzyme associated with anaerobic archaea and oxygen-deficient environments.	Li Y, Yu T, Feng X, Zhao B, Chen H, Yang H, Chen X, Zhang XH, Anderson HR, Burns NZ, Zeng F, Tao L, Zeng Z.	Nat Commun	10.1038/s41467-024-49650-x	2024
Transcriptome	Cometabolism of ferrihydrite reduction and methyl-dismutating methanogenesis by Methanosarcina mazei.	Guo C, Lu Y.	Appl Environ Microbiol	10.1128/aem.02238-24	2025
	The chromatin landscape of the euryarchaeon Haloferax volcanii.	Marinov GK, Bagdatli ST, Wu T, He C, Kundaje A, Greenleaf WJ.	Genome Biol	10.1186/s13059-023-03095-5	2023
Metabolism	Ammonia effect on hydrogenotrophic methanogens and syntrophic acetate-oxidizing bacteria.	Wang H, Fotidis IA, Angelidaki I.	FEMS Microbiol Ecol	10.1093/femsec/fiv130	2015
	Purification, kinetic characterization, and site-directed mutagenesis of Methanothermobacter thermautotrophicus RFAP Synthase Produced in Escherichia coli.	Bechard ME, Farahani P, Greene D, Pham A, Orry A, Rasche ME.	AIMS Microbiol	10.3934/microbiol.2019.3.186	2019
Metabolism	Electrochemical control of redox potential affects methanogenesis of the hydrogenotrophic methanogen Methanothermobacter thermautotrophicus.	Hirano S, Matsumoto N, Morita M, Sasaki K, Ohmura N.	Lett Appl Microbiol	10.1111/lam.12059	2013
Phylogeny	DUF99 family proteins are novel endonucleases that cleave deoxyuridine on DNA substrates.	Li J, Xia R, Huang WC, Gu J, Li M.	J Biol Chem	10.1016/j.jbc.2024.107901	2024
Genetics	The Archaeal Cell Cycle.	Cezanne A, Foo S, Kuo YW, Baum B.	Annu Rev Cell Dev Biol	10.1146/annurev-cellbio-111822-120242	2024
Transcriptome	Physiological and transcriptomic response to methyl-coenzyme M reductase limitation in Methanosarcina acetivorans.	Chadwick GL, Dury GA, Nayak DD.	Appl Environ Microbiol	10.1128/aem.02220-23	2024
	Ternary complexes of isopentenyl phosphate kinase from Thermococcus paralvinellae reveal molecular determinants of non-natural substrate specificity.	Johnson BP, Mandal PS, Brown SM, Thomas LM, Singh S.	Proteins	10.1002/prot.26674	2024
Genetics	Unveiling the Biodiversity of Hyperthermophilic Archaea in Jharia Coal Mines: Potential Threat to Methanogenesis?	Jha P, Singh J, Vidyarthi AS, Prasad R.	Curr Genomics	10.2174/1389202921999200605151722	2020
Metabolism	Acetate and Acetyl-CoA Metabolism of ANME-2 Anaerobic Archaeal Methanotrophs.	Ouboter HT, Arshad A, Berger S, Saucedo Sanchez JG, Op den Camp HJM, Jetten MSM, Welte CU, Kurth JM.	Appl Environ Microbiol	10.1128/aem.00367-23	2023
	Ammonia Production Using Bacteria and Yeast toward a Sustainable Society.	Watanabe Y, Aoki W, Ueda M.	Bioengineering (Basel)	10.3390/bioengineering10010082	2023
	Mono-, di- and trimethylated homologues of isoprenoid tetraether lipid cores in archaea and environmental samples: mass spectrometric identification and significance.	Knappy C, Barilla D, Chong J, Hodgson D, Morgan H, Suleman M, Tan C, Yao P, Keely B.	J Mass Spectrom	10.1002/jms.3709	2015
	The Effect of Saponite Clay on Ruminal Fermentation Parameters during In Vitro Studies.	Pikhtirova A, Pecka-Kielb E, Kroliczewska B, Zachwieja A, Kroliczewski J, Kupczynski R.	Animals (Basel)	10.3390/ani14050738	2024
Metabolism	Functional Nitrogenase Cofactor Maturase NifB in Mitochondria and Chloroplasts of Nicotiana benthamiana.	Jiang X, Coroian D, Barahona E, Echavarri-Erasun C, Castellanos-Rueda R, Eseverri A, Aznar-Moreno JA, Buren S, Rubio LM.	mBio	10.1128/mbio.00268-22	2022
	Members of the paralogous gene family 12 from the Lyme disease agent Borrelia burgdorferi are non-specific DNA-binding proteins.	Brangulis K, Akopjana I, Drunka L, Matisone S, Zelencova-Gopejenko D, Bhattacharya S, Bogans J, Tars K.	PLoS One	10.1371/journal.pone.0296127	2024
Metabolism	Mechanistic insights into Lhr helicase function in DNA repair.	Buckley RJ, Kramm K, Cooper CDO, Grohmann D, Bolt EL.	Biochem J	10.1042/bcj20200379	2020
	Optimization of the Ex Situ Biomethanation of Hydrogen and Carbon Dioxide in a Novel Meandering Plug Flow Reactor: Start-Up Phase and Flexible Operation.	Hoffstadt K, Nikolausz M, Krafft S, Bonatelli ML, Kumar V, Harms H, Kuperjans I.	Bioengineering (Basel)	10.3390/bioengineering11020165	2024
Metabolism	Reduction of Fe(III) oxides by phylogenetically and physiologically diverse thermophilic methanogens.	Yamada C, Kato S, Kimura S, Ishii M, Igarashi Y.	FEMS Microbiol Ecol	10.1111/1574-6941.12365	2014
	Putative nucleotide-based second messengers in archaea.	van der Does C, Braun F, Ren H, Albers SV.	Microlife	10.1093/femsml/uqad027	2023
	The effects of elevated CO2 concentration on competitive interaction between aceticlastic and syntrophic methanogenesis in a model microbial consortium.	Kato S, Yoshida R, Yamaguchi T, Sato T, Yumoto I, Kamagata Y.	Front Microbiol	10.3389/fmicb.2014.00575	2014
	3-Dimensional architecture of the human multi-tRNA synthetase complex.	Khan K, Baleanu-Gogonea C, Willard B, Gogonea V, Fox PL.	Nucleic Acids Res	10.1093/nar/gkaa569	2020
Genetics	Escherichia coli DNA repair helicase Lhr is also a uracil-DNA glycosylase.	Buckley RJ, Lou-Hing A, Hanson KM, Ahmed NR, Cooper CDO, Bolt EL.	Mol Microbiol	10.1111/mmi.15123	2023
	The mARS complex: a critical mediator of immune regulation and homeostasis.	Amanya SB, Oyewole-Said D, Ernste KJ, Bisht N, Murthy A, Vazquez-Perez J, Konduri V, Decker WK.	Front Immunol	10.3389/fimmu.2024.1423510	2024
Biotechnology	Systematic biotechnological production of isoprenoid analogs with bespoke carbon skeletons.	Wang L, Rosenfeldt M, Koutsaviti A, Harizani M, Zhao Y, Leelahakorn N, Frachon A, Raadam MH, Miettinen K, Pateraki I, Ioannou E, Kampranis SC.	Nat Commun	10.1038/s41467-025-57494-2	2025
	Impact of physical structure of granular sludge on methanogenesis and methanogenic community structure.	Pan X, Wang L, Lv N, Ning J, Zhou M, Wang T, Li C, Zhu G.	RSC Adv	10.1039/c9ra04257a	2019
	Predictions of DNA mechanical properties at a genomic scale reveal potentially new functional roles of DNA flexibility.	Back G, Walther D.	NAR Genom Bioinform	10.1093/nargab/lqad097	2023
Genetics	The solution structure of full-length dodecameric MCM by SANS and molecular modeling.	Krueger S, Shin JH, Curtis JE, Rubinson KA, Kelman Z.	Proteins	10.1002/prot.24598	2014
Metabolism	Syntrophic degradation of proteinaceous materials by the thermophilic strains Coprothermobacter proteolyticus and Methanothermobacter thermautotrophicus.	Sasaki K, Morita M, Sasaki D, Nagaoka J, Matsumoto N, Ohmura N, Shinozaki H.	J Biosci Bioeng	10.1016/j.jbiosc.2011.07.003	2011
	Expression of divergent methyl/alkyl coenzyme M reductases from uncultured archaea.	Shao N, Fan Y, Chou CW, Yavari S, Williams RV, Amster IJ, Brown SM, Drake IJ, Duin EC, Whitman WB, Liu Y.	Commun Biol	10.1038/s42003-022-04057-6	2022
Metabolism	Anaerobic digestion for simultaneous sewage sludge treatment and CO biomethanation: process performance and microbial ecology.	Luo G, Wang W, Angelidaki I.	Environ Sci Technol	10.1021/es401018d	2013
Enzymology	Mutational analysis of conserved aspartic acid residues in the Methanothermobacter thermautotrophicus MCM helicase.	Sakakibara N, Kasiviswanathan R, Kelman Z.	Extremophiles	10.1007/s00792-010-0352-1	2011
Pathogenicity	Harmaline-resistant mutant of Methanothermobacter thermautotrophicus with a lesion in Na(+)/H(+) antiport.	Vidova M, Bobalova J, Smigan P.	Gen Physiol Biophys	10.4149/gpb_2011_si1_54	2011
	The 23S Ribosomal RNA From Pyrococcus furiosus Is Circularly Permuted.	Birkedal U, Beckert B, Wilson DN, Nielsen H.	Front Microbiol	10.3389/fmicb.2020.582022	2020
Pathogenicity	Effects of 3-hydroxy-3-methylglutaryl-coenzyme a reductase inhibitor pravastatin on membrane lipids and membrane associated functions of Methanothermobacter thermautotrophicus.	Novakova Z, Blasko J, Hapala I, Smigan P.	Folia Microbiol (Praha)	10.1007/s12223-010-0058-x	2010
Metabolism	Methane production by Methanothermobacter thermautotrophicus to recover energy from carbon dioxide sequestered in geological reservoirs.	Kawaguchi H, Sakuma T, Nakata Y, Kobayashi H, Endo K, Sato K.	J Biosci Bioeng	10.1016/j.jbiosc.2010.01.008	2010
	Two-stage conversion of syngas and pyrolysis aqueous condensate into L-malate.	Robazza A, Baleeiro FCF, Kleinsteuber S, Neumann A.	Biotechnol Biofuels Bioprod	10.1186/s13068-024-02532-2	2024
	Microbial community shifts and biogas conversion computation during steady, inhibited and recovered stages of thermophilic methane fermentation on chicken manure with a wide variation of ammonia.	Niu Q, Qiao W, Qiang H, Li YY.	Bioresour Technol	10.1016/j.biortech.2013.07.038	2013
	Adaptive laboratory evolution of a thermophile toward a reduced growth temperature optimum.	Lehmann M, Prohaska C, Zeldes B, Poehlein A, Daniel R, Basen M.	Front Microbiol	10.3389/fmicb.2023.1265216	2023
	Monitoring of a microbial community during bioaugmentation with hydrogenotrophic methanogens to improve methane yield of an anaerobic digestion process.	Gallego-Bravo AK, Garcia-Mena J, Pina-Escobedo A, Lopez-Jimenez G, Gutierrez-Castillo ME, Tovar-Galvez LR.	Biotechnol Lett	10.1007/s10529-023-03414-7	2023
	In vivo structure probing of RNA in Archaea: novel insights into the ribosome structure of Methanosarcina acetivorans.	Williams AM, Jolley EA, Santiago-Martinez MG, Chan CX, Gutell RR, Ferry JG, Bevilacqua PC.	RNA	10.1261/rna.079687.123	2023
	Archaeal pseudomurein and bacterial murein cell wall biosynthesis share a common evolutionary ancestry.	Subedi BP, Martin WF, Carbone V, Duin EC, Cronin B, Sauter J, Schofield LR, Sutherland-Smith AJ, Ronimus RS.	FEMS Microbes	10.1093/femsmc/xtab012	2021
Enzymology	Structure of the Methanothermobacter thermautotrophicus exosome RNase PH ring.	Ng CL, Waterman DG, Antson AA, Ortiz-Lombardia M.	Acta Crystallogr D Biol Crystallogr	10.1107/s0907444910002908	2010
Metabolism	Co-digestion of manure and whey for in situ biogas upgrading by the addition of H(2): process performance and microbial insights.	Luo G, Angelidaki I.	Appl Microbiol Biotechnol	10.1007/s00253-012-4547-5	2013
Enzymology	Crystal structure of (S)-3-O-geranylgeranylglyceryl phosphate synthase from Thermoplasma acidophilum in complex with the substrate sn-glycerol 1-phosphate.	Nemoto N, Miyazono KI, Tanokura M, Yamagishi A.	Acta Crystallogr F Struct Biol Commun	10.1107/s2053230x19007453	2019
Pathogenicity	Isolation and characterization of a N,N'-dicyclohexylcarbodiimide-resistant mutant of Methanothermobacter thermautotrophicus with alterations to the ATP synthesis machinery.	Novakova Z, Majernik AI, Bobal'ova J, Vidova M, Smigan P.	Folia Microbiol (Praha)	10.1007/s12223-009-0068-8	2009
	PerR functions as a redox-sensing transcription factor regulating metal homeostasis in the thermoacidophilic archaeon Saccharolobus islandicus REY15A.	Zhang X, Wu P, Bai R, Gan Q, Yang Y, Li H, Ni J, Huang Q, Shen Y.	Nucleic Acids Res	10.1093/nar/gkae1263	2025
Genetics	An archaeal nucleoid-associated protein binds an essential motif in DNA replication origins	Dhanaraju R, Samson R, Feng X, Costa A, Gonzalez-Gutierrez G, Bell S.	Nat Commun		2025
Enzymology	Isolation of an Obligate Mixotrophic Methanogen That Represents the Major Population in Thermophilic Fixed-Bed Anaerobic Digesters.	Nagoya M, Kouzuma A, Ueno Y, Watanabe K.	Microorganisms	10.3390/microorganisms8020217	2020
	Effect of Inoculum Microbial Diversity in Ex Situ Biomethanation of Hydrogen.	Logrono W, Kluge P, Kleinsteuber S, Harms H, Nikolausz M.	Bioengineering (Basel)	10.3390/bioengineering9110678	2022
Pathogenicity	Tributyltin-resistant Methanothermobacter thermautotrophicus mutant with mutational substitutions in the A1A0-ATP synthase operon.	Novakova Z, Bobalova J, Vidova M, Hapala I, Smigan P.	FEMS Microbiol Lett	10.1111/j.1574-6968.2009.01725.x	2009
Metabolism	[Detection of the quorum sensing signals in methanogenic archaea].	Guo X, Zhang G, Liu X, Ma K, Dong X.	Wei Sheng Wu Xue Bao		2011
Metabolism	Membrane proteins and squalene-hydrosqualene profile in methanoarchaeon Methanothermobacter thermautotrophicus resistant to N,N'-dicyclohexylcarbodiimide.	Novakova Z, Surin S, Blasko J, Majernik A, Smigan P.	Folia Microbiol (Praha)	10.1007/s12223-008-0034-x	2008
Enzymology	The Methanothermobacter thermautotrophicus MCM helicase is active as a hexameric ring.	Shin JH, Heo GY, Kelman Z.	J Biol Chem	10.1074/jbc.m806803200	2009
Metabolism	Glucose Metabolism and Acetate Switch in Archaea: the Enzymes in Haloferax volcanii.	Kuprat T, Ortjohann M, Johnsen U, Schonheit P.	J Bacteriol	10.1128/jb.00690-20	2021
Metabolism	Sodium ion translocation and ATP synthesis in methanogens.	Schlegel K, Muller V.	Methods Enzymol	10.1016/b978-0-12-385112-3.00012-3	2011
	Evidence for Enzymatic Backbone Methylation of the Main Membrane Lipids in the Archaeon Methanomassiliicoccus luminyensis.	Coffinet S, Muhlena L, Lipp JS, Weil M, Neubauer C, Urich T, Hinrichs KU.	Appl Environ Microbiol	10.1128/aem.02154-21	2022
	Molecular characterization of microorganisms with industrial potential for methane production in sludge from Kangemi sewage treatment plant, Nyeri county-Kenya.	Kimisto AK, Muia AW, Ong'ondo GO, Ndung'u KC.	Heliyon	10.1016/j.heliyon.2023.e15715	2023
	Methanogenic partner influences cell aggregation and signalling of Syntrophobacterium fumaroxidans.	Doloman A, Besteman MS, Sanders MG, Sousa DZ.	Appl Microbiol Biotechnol	10.1007/s00253-023-12955-w	2024
Pathogenicity	Deazaflavin metabolite produced by endosymbiotic bacteria controls fungal host reproduction.	Richter I, Hasan M, Kramer JW, Wein P, Krabbe J, Wojtas KP, Stinear TP, Pidot SJ, Kloss F, Hertweck C, Lackner G.	ISME J	10.1093/ismejo/wrae074	2024
	Osmotic stress responses and the biology of the second messenger c-di-AMP in Streptomyces.	Bhowmick S, Shenouda ML, Tschowri N.	Microlife	10.1093/femsml/uqad020	2023
Phenotype	Phenotypic and genomic characterization of Methanothermobacter wolfeii strain BSEL, a CO₂-capturing archaeon with minimal nutrient requirements.	Ale Enriquez F, Ahring BK.	Appl Environ Microbiol	10.1128/aem.00268-24	2024
	Microbial Consortiums of Hydrogenotrophic Methanogenic Mixed Cultures in Lab-Scale Ex-Situ Biogas Upgrading Systems under Different Conditions of Temperature, pH and CO.	Xu J, Bu F, Zhu W, Luo G, Xie L.	Microorganisms	10.3390/microorganisms8050772	2020
	Microbial diversity with dominance of 16S rRNA gene sequences with high GC contents at 74 and 98 °C subsurface crude oil deposits in Japan.	Yamane K, Hattori Y, Ohtagaki H, Fujiwara K.	FEMS Microbiol Ecol	10.1111/j.1574-6941.2011.01044.x	2011
	Nitrogenase cofactor biosynthesis using proteins produced in mitochondria of Saccharomyces cerevisiae.	Dobrzynska K, Perez-Gonzalez A, Echavarri-Erasun C, Coroian D, Salinero-Lanzarote A, Veldhuizen M, Dean DR, Buren S, Rubio LM.	mBio	10.1128/mbio.03088-23	2024
	Diversity and function of methyl-coenzyme M reductase-encoding archaea in Yellowstone hot springs revealed by metagenomics and mesocosm experiments.	Lynes MM, Krukenberg V, Jay ZJ, Kohtz AJ, Gobrogge CA, Spietz RL, Hatzenpichler R.	ISME Commun	10.1038/s43705-023-00225-9	2023
Metabolism	Genetic Study of Four Candidate Holliday Junction Processing Proteins in the Thermophilic Crenarchaeon Sulfolobus acidocaldarius.	Matsuda R, Suzuki S, Kurosawa N.	Int J Mol Sci	10.3390/ijms23020707	2022
	Photosynthesis: Genetic Strategies Adopted to Gain Higher Efficiency.	Khan N, Choi SH, Lee CH, Qu M, Jeon JS.	Int J Mol Sci	10.3390/ijms25168933	2024
Metabolism	Alternative Pathways of Acetogenic Ethanol and Methanol Degradation in the Thermophilic Anaerobe Thermacetogenium phaeum.	Keller A, Schink B, Muller N.	Front Microbiol	10.3389/fmicb.2019.00423	2019
	Evolving understanding of rumen methanogen ecophysiology.	Khairunisa BH, Heryakusuma C, Ike K, Mukhopadhyay B, Susanti D.	Front Microbiol	10.3389/fmicb.2023.1296008	2023
Metabolism	Certain, but Not All, Tetraether Lipids from the Thermoacidophilic Archaeon Sulfolobus acidocaldarius Can Form Black Lipid Membranes with Remarkable Stability and Exhibiting Mthk Channel Activity with Unusually High Ca²⁺ Sensitivity.	Bonanno A, Chong PL.	Int J Mol Sci	10.3390/ijms222312941	2021
Metabolism	Evolution of initiator tRNAs and selection of methionine as the initiating amino acid.	Bhattacharyya S, Varshney U.	RNA Biol	10.1080/15476286.2016.1195943	2016
Phylogeny	Isolation and characterization of an amiloride-resistant mutant of Methanothermobacter thermautotrophicus possessing a defective Na+/H+ antiport.	Surin S, Cubonova L, Majernik AI, McDermott P, Chong JP, Smigan P.	FEMS Microbiol Lett	10.1111/j.1574-6968.2007.00655.x	2007
Metabolism	Something special about CO-dependent CO₂ fixation.	Xavier JC, Preiner M, Martin WF.	FEBS J	10.1111/febs.14664	2018
	An Aggregation-defective Mutant of Methanothermobacter sp. CaT2 Reveals Unique Protein-dependent Aggregation.	Sumikawa K, Kosaka T, Mayahara N, Matsutani M, Udo K, Yamada M.	Microbes Environ	10.1264/jsme2.me19014	2019
Transcriptome	Growth of soil ammonia-oxidizing archaea on air-exposed solid surface.	Abiola C, Gwak JH, Lee UJ, Awala SI, Jung MY, Park W, Rhee SK.	ISME Commun	10.1093/ismeco/ycae129	2024
Enzymology	ATP hydrolysis and DNA binding confer thermostability on the MCM helicase.	Sakakibara N, Schwarz FP, Kelman Z.	Biochemistry	10.1021/bi801921j	2009
Phylogeny	Isolation and characterization of a new strain of Methanothermobacter marburgensis DX01 from hot springs in China.	Ding X, Yang WJ, Min H, Peng XT, Zhou HY, Lu ZM.	Anaerobe	10.1016/j.anaerobe.2009.04.001	2010
	Evolutionary and functional insights into the Ski2-like helicase family in Archaea: a comparison of Thermococcales ASH-Ski2 and Hel308 activities.	Batista M, Langendijk-Genevaux P, Kwapisz M, Canal I, Phung DK, Plassart L, Capeyrou R, Moalic Y, Jebbar M, Flament D, Fichant G, Bouvier M, Clouet-d'Orval B.	NAR Genom Bioinform	10.1093/nargab/lqae026	2024
Enzymology	Archaeal Nucleic Acid Ligases and Their Potential in Biotechnology.	Chambers CR, Patrick WM.	Archaea	10.1155/2015/170571	2015
Biotechnology	Quantitative Analysis of Core Lipid Production in Methanothermobacter marburgensis at Different Scales.	Baumann LMF, Taubner RS, Olah K, Rohrweber AC, Schuster B, Birgel D, Rittmann SKR.	Bioengineering (Basel)	10.3390/bioengineering9040169	2022
Metabolism	Archaeal minichromosome maintenance (MCM) helicase can unwind DNA bound by archaeal histones and transcription factors.	Shin JH, Santangelo TJ, Xie Y, Reeve JN, Kelman Z.	J Biol Chem	10.1074/jbc.m606847200	2007
	Differential stability of TATA box binding proteins from archaea with different optimal growth temperatures.	Kopitz A, Soppa J, Krejtschi C, Hauser K.	Spectrochim Acta A Mol Biomol Spectrosc	10.1016/j.saa.2009.04.002	2009
	Controlling Enzymatic Activity by Modulating the Oligomerization State via Chemical Rescue and Optical Control.	Kropp C, Bruckmann A, Babinger P.	Chembiochem	10.1002/cbic.202100490	2022
Metabolism	Non-essential MCM-related proteins mediate a response to DNA damage in the archaeon Methanococcus maripaludis.	Walters AD, Chong JPJ.	Microbiology (Reading)	10.1099/mic.0.000460	2017
	Metabolic engineering of Methylobacterium extorquens AM1 for the production of butadiene precursor.	Yang J, Zhang CT, Yuan XJ, Zhang M, Mo XH, Tan LL, Zhu LP, Chen WJ, Yao MD, Hu B, Yang S.	Microb Cell Fact	10.1186/s12934-018-1042-4	2018
Metabolism	Biosynthesis of the nitrogenase active-site cofactor precursor NifB-co in Saccharomyces cerevisiae.	Buren S, Pratt K, Jiang X, Guo Y, Jimenez-Vicente E, Echavarri-Erasun C, Dean DR, Saaem I, Gordon DB, Voigt CA, Rubio LM.	Proc Natl Acad Sci U S A	10.1073/pnas.1904903116	2019
	Comparative Metagenomic Analysis of Electrogenic Microbial Communities in Differentially Inoculated Swine Wastewater-Fed Microbial Fuel Cells.	Khilyas IV, Sorokin AA, Kiseleva L, Simpson DJW, Fedorovich V, Sharipova MR, Kainuma M, Cohen MF, Goryanin I.	Scientifica (Cairo)	10.1155/2017/7616359	2017
	Insights into the architecture of the replicative helicase from the structure of an archaeal MCM homolog.	Bae B, Chen YH, Costa A, Onesti S, Brunzelle JS, Lin Y, Cann IK, Nair SK.	Structure	10.1016/j.str.2008.11.010	2009
	Hydrogenotrophs-Based Biological Biogas Upgrading Technologies.	Antukh T, Lee I, Joo S, Kim H.	Front Bioeng Biotechnol	10.3389/fbioe.2022.833482	2022
Enzymology	Exploiting genetic diversity and gene synthesis to identify superior nitrogenase NifH protein variants to engineer N₂-fixation in plants.	Jiang X, Paya-Tormo L, Coroian D, Garcia-Rubio I, Castellanos-Rueda R, Eseverri A, Lopez-Torrejon G, Buren S, Rubio LM.	Commun Biol	10.1038/s42003-020-01536-6	2021
Enzymology	Elucidation of substrate specificity in the cobalamin (vitamin B12) biosynthetic methyltransferases. Structure and function of the C20 methyltransferase (CbiL) from Methanothermobacter thermautotrophicus.	Frank S, Deery E, Brindley AA, Leech HK, Lawrence A, Heathcote P, Schubert HL, Brocklehurst K, Rigby SE, Warren MJ, Pickersgill RW.	J Biol Chem	10.1074/jbc.m703827200	2007
	Growth Coordination Between Butyrate-Oxidizing Syntrophs and Hydrogenotrophic Methanogens.	Cong S, Xu Y, Lu Y.	Front Microbiol	10.3389/fmicb.2021.742531	2021
Metabolism	Deconstructing Methanosarcina acetivorans into an acetogenic archaeon.	Schone C, Poehlein A, Jehmlich N, Adlung N, Daniel R, von Bergen M, Scheller S, Rother M.	Proc Natl Acad Sci U S A	10.1073/pnas.2113853119	2022
	Reduction of hexavalent chromium by the thermophilic methanogen Methanothermobacter thermautotrophicus.	Singh R, Dong H, Liu D, Zhao L, Marts AR, Farquhar E, Tierney DL, Almquist CB, Briggs BR.	Geochim Cosmochim Acta	10.1016/j.gca.2014.10.012	2015
	Structural polymorphism of Methanothermobacter thermautotrophicus MCM.	Chen YJ, Yu X, Kasiviswanathan R, Shin JH, Kelman Z, Egelman EH.	J Mol Biol	10.1016/j.jmb.2004.11.076	2005
Genetics	Reprogramming Microbial CO₂-Metabolizing Chassis With CRISPR-Cas Systems.	Yu HY, Wang SG, Xia PF.	Front Bioeng Biotechnol	10.3389/fbioe.2022.897204	2022
Metabolism	Stable acetate production in extreme-thermophilic (70°C) mixed culture fermentation by selective enrichment of hydrogenotrophic methanogens.	Zhang F, Zhang Y, Ding J, Dai K, van Loosdrecht MC, Zeng RJ.	Sci Rep	10.1038/srep05268	2014
	Effects of nickel and cobalt on methane production and methanogen abundance and diversity in paddy soil.	Wang T, Li Z, Chen X, Long XE.	PeerJ	10.7717/peerj.6274	2019
Metabolism	Isolation and characterization of an uncoupler-resistant mutant of Methanothermobacter thermautotrophicus.	Cubonova L, Surin S, Majernik A, Smigan P.	FEMS Microbiol Lett	10.1016/j.femsle.2004.01.033	2004
Enzymology	A recombinant exonuclease III homologue of the thermophilic archaeon Methanothermobacter thermautotrophicus.	Pfeifer S, Greiner-Stoffele T.	DNA Repair (Amst)	10.1016/j.dnarep.2004.11.008	2005
Metabolism	Effect of temperature on microbial community of a glucose-degrading methanogenic consortium under hyperthermophilic chemostat cultivation.	Tang YQ, Matsui T, Morimura S, Wu XL, Kida K.	J Biosci Bioeng	10.1263/jbb.106.180	2008
	Biochemical characterization of the Methanothermobacter thermautotrophicus minichromosome maintenance (MCM) helicase N-terminal domains.	Kasiviswanathan R, Shin JH, Melamud E, Kelman Z.	J Biol Chem	10.1074/jbc.m403202200	2004
	Protein complexes in the archaeon Methanothermobacter thermautotrophicus analyzed by blue native/SDS-PAGE and mass spectrometry.	Farhoud MH, Wessels HJ, Steenbakkers PJ, Mattijssen S, Wevers RA, van Engelen BG, Jetten MS, Smeitink JA, van den Heuvel LP, Keltjens JT.	Mol Cell Proteomics	10.1074/mcp.m500171-mcp200	2005
Pathogenicity	Biochemical characteristics of a mutant of the methanoarchaeon Methanothermobacter thermautotrophicus resistant to the protonophoric uncoupler TCS.	Cijbonova L, Majernik A, Smigan P.	Folia Microbiol (Praha)	10.1007/bf02931390	2004
Biotechnology	Lipidomics and Comparative Metabolite Excretion Analysis of Methanogenic Archaea Reveal Organism-Specific Adaptations to Varying Temperatures and Substrate Concentrations.	Taubner RS, Baumann LMF, Steiner M, Pfeifer K, Reischl B, Korynt K, Bauersachs T, Mahnert B, Clifford EL, Peckmann J, Schuster B, Birgel D, Rittmann SKR.	mSystems	10.1128/msystems.01159-22	2023
	AMP-dependent phosphite dehydrogenase, a phosphorylating enzyme in dissimilatory phosphite oxidation.	Mao Z, Fleming JR, Mayans O, Frey J, Schleheck D, Schink B, Muller N.	Proc Natl Acad Sci U S A	10.1073/pnas.2309743120	2023
Genetics	An Efficient, Nonphylogenetic Method for Detecting Genes Sharing Evolutionary Signals in Phylogenomic Data Sets.	Rangel LT, Soucy SM, Setubal JC, Gogarten JP, Fournier GP.	Genome Biol Evol	10.1093/gbe/evab187	2021
Metabolism	A conserved mechanism for replication origin recognition and binding in archaea.	Majernik AI, Chong JP.	Biochem J	10.1042/bj20070213	2008
	Functional expression of the nitrogenase Fe protein in transgenic rice.	Baysal C, Buren S, He W, Jiang X, Capell T, Rubio LM, Christou P.	Commun Biol	10.1038/s42003-022-03921-9	2022
Metabolism	High-temperature single-molecule kinetic analysis of thermophilic archaeal MCM helicases.	Schermerhorn KM, Tanner N, Kelman Z, Gardner AF.	Nucleic Acids Res	10.1093/nar/gkw612	2016
	Controls on the isotopic composition of microbial methane.	Gropp J, Jin Q, Halevy I.	Sci Adv	10.1126/sciadv.abm5713	2022
Metabolism	Different residues on the surface of the Methanothermobacter thermautotrophicus MCM helicase interact with single- and double-stranded DNA.	Sakakibara N, Kasiviswanathan R, Kelman Z.	Archaea	10.1155/2010/505693	2010
Metabolism	The mesophilic archaeon Methanosarcina acetivorans counteracts uracil in DNA with multiple enzymes: EndoQ, ExoIII, and UDG.	Shiraishi M, Ishino S, Heffernan M, Cann I, Ishino Y.	Sci Rep	10.1038/s41598-018-34000-x	2018
Metabolism	The TK0271 Protein Activates Transcription of Aromatic Amino Acid Biosynthesis Genes in the Hyperthermophilic Archaeon Thermococcus kodakarensis.	Yamamoto Y, Kanai T, Kaneseki T, Atomi H.	mBio	10.1128/mbio.01213-19	2019
	Comparative analysis of differential proteome-wide protein-protein interaction network of Methanobrevibacter ruminantium M1.	M B, P C.	Biochem Biophys Rep	10.1016/j.bbrep.2019.100698	2019
Metabolism	A minimum of three motifs is essential for optimal binding of pseudomurein cell wall-binding domain of Methanothermobacter thermautotrophicus.	Visweswaran GR, Dijkstra BW, Kok J.	PLoS One	10.1371/journal.pone.0021582	2011
Metabolism	Microbial diversity and methanogenic potential in a high temperature natural gas field in Japan.	Mochimaru H, Yoshioka H, Tamaki H, Nakamura K, Kaneko N, Sakata S, Imachi H, Sekiguchi Y, Uchiyama H, Kamagata Y.	Extremophiles	10.1007/s00792-006-0056-8	2007
Metabolism	Archaeal chromatin proteins histone HMtB and Alba have lost DNA-binding ability in laboratory strains of Methanothermobacter thermautotrophicus.	Sandman K, Louvel H, Samson RY, Pereira SL, Reeve JN.	Extremophiles	10.1007/s00792-008-0185-3	2008
	Novel Homologs of Isopentenyl Phosphate Kinase Reveal Class-Wide Substrate Flexibility.	Kumar V, Johnson BP, Dimas DA, Singh S.	ChemCatChem	10.1002/cctc.202100595	2021
	Functionalized Membrane Domains: An Ancestral Feature of Archaea?	Tourte M, Schaeffer P, Grossi V, Oger PM.	Front Microbiol	10.3389/fmicb.2020.00526	2020
Enzymology	Functional association between three archaeal aminoacyl-tRNA synthetases.	Praetorius-Ibba M, Hausmann CD, Paras M, Rogers TE, Ibba M.	J Biol Chem	10.1074/jbc.m609988200	2007
Genetics	Characterization of promoters in archaeal genomes based on DNA structural parameters.	Martinez GS, Sarkar S, Kumar A, Perez-Rueda E, de Avila E Silva S.	Microbiologyopen	10.1002/mbo3.1230	2021
	Phytobacter diazotrophicus from Intestine of Caenorhabditis elegans Confers Colonization-Resistance against Bacillus nematocida Using Flagellin (FliC) as an Inhibition Factor.	Niu Q, Liu S, Yin M, Lei S, Rezzonico F, Zhang L.	Pathogens	10.3390/pathogens11010082	2022
Metabolism	Transfer of pro-R hydrogen from NADH to dihydroxyacetonephosphate by sn-glycerol-1-phosphate dehydrogenase from the archaeon Methanothermobacter thermautotrophicus.	Koga Y, Sone N, Noguchi S, Morii H.	Biosci Biotechnol Biochem	10.1271/bbb.67.1605	2003
Metabolism	Identification of pseudomurein cell wall binding domains.	Steenbakkers PJ, Geerts WJ, Ayman-Oz NA, Keltjens JT.	Mol Microbiol	10.1111/j.1365-2958.2006.05483.x	2006
Metabolism	A single-culture bioprocess of Methanothermobacter thermautotrophicus to upgrade digester biogas by CO2 -to-CH4 conversion with H2.	Martin MR, Fornero JJ, Stark R, Mets L, Angenent LT.	Archaea	10.1155/2013/157529	2013
	The role of Cas8 in type I CRISPR interference.	Cass SD, Haas KA, Stoll B, Alkhnbashi OS, Sharma K, Urlaub H, Backofen R, Marchfelder A, Bolt EL.	Biosci Rep	10.1042/bsr20150043	2015
	Preliminary crystallography confirms that the archaeal DNA-binding and tryptophan-sensing regulator TrpY is a dimer.	Cafasso J, Manjasetty BA, Karr EA, Sandman K, Chance MR, Reeve JN.	Acta Crystallogr Sect F Struct Biol Cryst Commun	10.1107/s1744309110036031	2010
Metabolism	Archaeal RNA polymerase is sensitive to intrinsic termination directed by transcribed and remote sequences.	Santangelo TJ, Reeve JN.	J Mol Biol	10.1016/j.jmb.2005.10.062	2006
Metabolism	Structural basis of RNA-dependent recruitment of glutamine to the genetic code.	Oshikane H, Sheppard K, Fukai S, Nakamura Y, Ishitani R, Numata T, Sherrer RL, Feng L, Schmitt E, Panvert M, Blanquet S, Mechulam Y, Soll D, Nureki O.	Science	10.1126/science.1128470	2006
Enzymology	Phylogenetic Diversity of Lhr Proteins and Biochemical Activities of the Thermococcales aLhr2 DNA/RNA Helicase.	Hajj M, Langendijk-Genevaux P, Batista M, Quentin Y, Laurent S, Capeyrou R, Abdel-Razzak Z, Flament D, Chamieh H, Fichant G, Clouet-d'Orval B, Bouvier M.	Biomolecules	10.3390/biom11070950	2021
Metabolism	Bioenergetics of the formyl-methanofuran dehydrogenase and heterodisulfide reductase reactions in Methanothermobacter thermautotrophicus.	de Poorter LM, Geerts WG, Theuvenet AP, Keltjens JT.	Eur J Biochem	10.1046/j.1432-1033.2003.03362.x	2003
	Expression, purification, crystallization and preliminary X-ray studies of the TAN1 orthologue from Methanothermobacter thermautotrophicus.	Silva AP, Byrne RT, Chechik M, Smits C, Waterman DG, Antson AA.	Acta Crystallogr Sect F Struct Biol Cryst Commun	10.1107/s1744309108034039	2008
	Archaea: The Final Frontier of Chromatin.	Laursen SP, Bowerman S, Luger K.	J Mol Biol	10.1016/j.jmb.2020.166791	2021
	Biological treatment of biowaste as an innovative source of CO-The role of composting process.	Sobieraj K, Stegenta-Dabrowska S, Luo G, Koziel JA, Bialowiec A.	Front Bioeng Biotechnol	10.3389/fbioe.2023.1126737	2023
Metabolism	Acetate production from lactose by Clostridium thermolacticum and hydrogen-scavenging microorganisms in continuous culture--effect of hydrogen partial pressure.	Collet C, Gaudard O, Peringer P, Schwitzguebel JP.	J Biotechnol	10.1016/j.jbiotec.2005.05.011	2005
	Identification of amino acids important for the biochemical activity of Methanothermobacter thermautotrophicus MCM.	Fletcher RJ, Shen J, Holden LG, Chen XS.	Biochemistry	10.1021/bi800032t	2008
Metabolism	Analysis of Haloferax mediterranei Lrp Transcriptional Regulator.	Matarredona L, Camacho M, Garcia-Bonete MJ, Esquerra B, Zafrilla B, Esclapez J, Bonete MJ.	Genes (Basel)	10.3390/genes12060802	2021
	DNAcycP: a deep learning tool for DNA cyclizability prediction.	Li K, Carroll M, Vafabakhsh R, Wang XA, Wang JP.	Nucleic Acids Res	10.1093/nar/gkac162	2022
Enzymology	Two major archaeal pseudomurein endoisopeptidases: PeiW and PeiP.	Visweswaran GR, Dijkstra BW, Kok J.	Archaea	10.1155/2010/480492	2010
	Genome-resolved metagenomics and metatranscriptomics reveal niche differentiation in functionally redundant microbial communities at deep-sea hydrothermal vents.	Galambos D, Anderson RE, Reveillaud J, Huber JA.	Environ Microbiol	10.1111/1462-2920.14806	2019
Metabolism	Hydrogen concentrations in methane-forming cells probed by the ratios of reduced and oxidized coenzyme F420.	de Poorter LMI, Geerts WJ, Keltjens JT.	Microbiology (Reading)	10.1099/mic.0.27679-0	2005
Metabolism	Reconstruction of the Diaminopimelic Acid Pathway to Promote L-lysine Production in Corynebacterium glutamicum.	Liu N, Zhang TT, Rao ZM, Zhang WG, Xu JZ.	Int J Mol Sci	10.3390/ijms22169065	2021
Metabolism	Biochemistry and physiology of the beta class carbonic anhydrase (Cpb) from Clostridium perfringens strain 13.	Kumar RS, Hendrick W, Correll JB, Patterson AD, Melville SB, Ferry JG.	J Bacteriol	10.1128/jb.02288-12	2013
Metabolism	The Methanothermobacter thermautotrophicus Cdc6-2 protein, the putative helicase loader, dissociates the minichromosome maintenance helicase.	Shin JH, Heo GY, Kelman Z.	J Bacteriol	10.1128/jb.00233-08	2008
Metabolism	Expression, Purification, and Characterization of (R)-Sulfolactate Dehydrogenase (ComC) from the Rumen Methanogen Methanobrevibacter millerae SM9.	Zhang Y, Schofield LR, Sang C, Dey D, Ronimus RS.	Archaea	10.1155/2017/5793620	2017
Metabolism	The Oligosaccharyltransferase AglB Supports Surface-Associated Growth and Iron Oxidation in Methanococcus maripaludis.	Holten MP, Fonseca DR, Costa KC.	Appl Environ Microbiol	10.1128/aem.00995-21	2021
Genetics	Genome-Resolved Meta-Analysis of the Microbiome in Oil Reservoirs Worldwide.	Hidalgo KJ, Sierra-Garcia IN, Zafra G, de Oliveira VM.	Microorganisms	10.3390/microorganisms9091812	2021
	Organelle-dependent polyprotein designs enable stoichiometric expression of nitrogen fixation components targeted to mitochondria.	Yang J, Xiang N, Liu Y, Guo C, Li C, Li H, Cai S, Dixon R, Wang YP.	Proc Natl Acad Sci U S A	10.1073/pnas.2305142120	2023
Enzymology	Molecular Basis for the Substrate Promiscuity of Isopentenyl Phosphate Kinase from Candidatus methanomethylophilus alvus.	Johnson BP, Kumar V, Scull EM, Thomas LM, Bourne CR, Singh S.	ACS Chem Biol	10.1021/acschembio.1c00655	2022
Metabolism	Redox-sensitive DNA binding by homodimeric Methanosarcina acetivorans MsvR is modulated by cysteine residues.	Isom CE, Turner JL, Lessner DJ, Karr EA.	BMC Microbiol	10.1186/1471-2180-13-163	2013
	Archaeal nucleosome positioning in vivo and in vitro is directed by primary sequence motifs.	Nalabothula N, Xi L, Bhattacharyya S, Widom J, Wang JP, Reeve JN, Santangelo TJ, Fondufe-Mittendorf YN.	BMC Genomics	10.1186/1471-2164-14-391	2013
	RNA granule-clustered mitochondrial aminoacyl-tRNA synthetases form multiple complexes with the potential to fine-tune tRNA aminoacylation.	Peng GX, Mao XL, Cao Y, Yao SY, Li QR, Chen X, Wang ED, Zhou XL.	Nucleic Acids Res	10.1093/nar/gkac1141	2022
	Emerging views of genome organization in Archaea.	Takemata N, Bell SD.	J Cell Sci	10.1242/jcs.243782	2020
Metabolism	Coenzyme F₄₂₀-Dependent Glucose-6-Phosphate Dehydrogenase-Coupled Polyglutamylation of Coenzyme F₄₂₀ in Mycobacteria.	Purwantini E, Loganathan U, Mukhopadhyay B.	J Bacteriol	10.1128/jb.00375-18	2018
Metabolism	A new type of sulfite reductase, a novel coenzyme F420-dependent enzyme, from the methanarchaeon Methanocaldococcus jannaschii.	Johnson EF, Mukhopadhyay B.	J Biol Chem	10.1074/jbc.m503492200	2005
Metabolism	Homologous recombination in Archaea: new Holliday junction helicases.	Bolt EL, Guy CP.	Biochem Soc Trans	10.1042/bst0310703	2003
	Enhanced methane production from cellulose using a two-stage process involving a bioelectrochemical system and a fixed film reactor.	Sasaki K, Sasaki D, Tsuge Y, Morita M, Kondo A.	Biotechnol Biofuels	10.1186/s13068-020-01866-x	2021
	Accurate Representation of Protein-Ligand Structural Diversity in the Protein Data Bank (PDB).	Shinada NK, Schmidtke P, de Brevern AG.	Int J Mol Sci	10.3390/ijms21062243	2020
	An Improved Natural Transformation Protocol for the Cyanobacterium Synechocystis sp. PCC 6803.	Pope MA, Hodge JA, Nixon PJ.	Front Plant Sci	10.3389/fpls.2020.00372	2020
	Mechanical and structural properties of archaeal hypernucleosomes.	Henneman B, Brouwer TB, Erkelens AM, Kuijntjes GJ, van Emmerik C, van der Valk RA, Timmer M, Kirolos NCS, van Ingen H, van Noort J, Dame RT.	Nucleic Acids Res	10.1093/nar/gkaa1196	2021
	The methanogen-specific transcription factor MsvR regulates the fpaA-rlp-rub oxidative stress operon adjacent to msvR in Methanothermobacter thermautotrophicus.	Karr EA.	J Bacteriol	10.1128/jb.00816-10	2010
	Gln-tRNAGln formation from Glu-tRNAGln requires cooperation of an asparaginase and a Glu-tRNAGln kinase.	Feng L, Sheppard K, Tumbula-Hansen D, Soll D.	J Biol Chem	10.1074/jbc.m411098200	2005
	Effects of ferrous iron supplementation on reductive dechlorination of tetrachloroethene and on methanogenic microbial community.	Yoshikawa M, Zhang M, Kawabe Y, Katayama T.	FEMS Microbiol Ecol	10.1093/femsec/fiab069	2021
Metabolism	Voltage vs. Ligand II: Structural insights of the intrinsic flexibility in cyclic nucleotide-gated channels.	Romero-Romero S, Martinez-Delgado G, Balleza D.	Channels (Austin)	10.1080/19336950.2019.1666456	2019
	Arsenic metabolism in technical biogas plants: possible consequences for resident microbiota and downstream units.	Weithmann N, Mlinar S, Hilbrig F, Bachmaf S, Arndt J, Planer-Friedrich B, Weig AR, Freitag R.	AMB Express	10.1186/s13568-019-0902-6	2019
Enzymology	Mutational analysis of an archaeal minichromosome maintenance protein exterior hairpin reveals critical residues for helicase activity and DNA binding.	Brewster AS, Slaymaker IM, Afif SA, Chen XS.	BMC Mol Biol	10.1186/1471-2199-11-62	2010
	Interspecies Horizontal Transfer and Specific Integration of the Mosquitocidal Toxin-Encoding Plasmid pTAND672-2 from Bacillus thuringiensis subsp. israelensis to Lysinibacillus sphaericus.	Geng P, Zhao P, Wan X, Mahillon J, Hu Y, Gong Y, Hu X.	Appl Environ Microbiol	10.1128/aem.01652-22	2023
	Correlating ion channel structure and function.	Schmidpeter PAM, Nimigean CM.	Methods Enzymol	10.1016/bs.mie.2021.02.016	2021
Metabolism	Archaeal Inorganic Pyrophosphatase Displays Robust Activity under High-Salt Conditions and in Organic Solvents.	McMillan LJ, Hepowit NL, Maupin-Furlow JA.	Appl Environ Microbiol	10.1128/aem.03055-15	2016
Enzymology	Archaeal community compositions at different depths (up to 30 m) of a municipal solid waste landfill in Taiwan as revealed by 16S rDNA cloning analyses.	Chen AC, Imachi H, Sekiguchi Y, Ohashi A, Harada H.	Biotechnol Lett	10.1023/a:1023458631699	2003
	Regulation of minichromosome maintenance helicase activity by Cdc6.	Shin JH, Grabowski B, Kasiviswanathan R, Bell SD, Kelman Z.	J Biol Chem	10.1074/jbc.m305477200	2003
Enzymology	Genetic confirmation of the role of sulfopyruvate decarboxylase in coenzyme M biosynthesis in Methanococcus maripaludis.	Sarmiento F, Ellison CK, Whitman WB.	Archaea	10.1155/2013/185250	2013
	Computational engineering of previously crystallized pyruvate formate-lyase activating enzyme reveals insights into SAM binding and reductive cleavage.	Moody JD, Hill S, Lundahl MN, Saxton AJ, Galambas A, Broderick WE, Lawrence CM, Broderick JB.	J Biol Chem	10.1016/j.jbc.2023.104791	2023
Enzymology	Evolution of vitamin B2 biosynthesis. A novel class of riboflavin synthase in Archaea.	Fischer M, Schott AK, Romisch W, Ramsperger A, Augustin M, Fidler A, Bacher A, Richter G, Huber R, Eisenreich W.	J Mol Biol	10.1016/j.jmb.2004.08.016	2004
Metabolism	PredHSP: Sequence Based Proteome-Wide Heat Shock Protein Prediction and Classification Tool to Unlock the Stress Biology.	Kumar R, Kumari B, Kumar M.	PLoS One	10.1371/journal.pone.0155872	2016
Lipids	Novel Intact Polar and Core Lipid Compositions in the Pyrococcus Model Species, P. furiosus and P. yayanosii, Reveal the Largest Lipid Diversity Amongst Thermococcales.	Tourte M, Kuentz V, Schaeffer P, Grossi V, Cario A, Oger PM.	Biomolecules	10.3390/biom10060830	2020
Enzymology	Metabolic Strategies Shared by Basement Residents of the Lost City Hydrothermal Field.	Brazelton WJ, McGonigle JM, Motamedi S, Pendleton HL, Twing KI, Miller BC, Lowe WJ, Hoffman AM, Prator CA, Chadwick GL, Anderson RE, Thomas E, Butterfield DA, Aquino KA, Fruh-Green GL, Schrenk MO, Lang SQ.	Appl Environ Microbiol	10.1128/aem.00929-22	2022
	Thermal adaptation of the archaeal and bacterial lipid membranes.	Koga Y.	Archaea	10.1155/2012/789652	2012
Metabolism	Substrate requirements for duplex DNA translocation by the eukaryal and archaeal minichromosome maintenance helicases.	Shin JH, Jiang Y, Grabowski B, Hurwitz J, Kelman Z.	J Biol Chem	10.1074/jbc.m308599200	2003
	DNA content and nucleoid distribution in Methanothermobacter thermautotrophicus.	Majernik AI, Lundgren M, McDermott P, Bernander R, Chong JP.	J Bacteriol	10.1128/jb.187.5.1856-1858.2005	2005
Enzymology	Archaeal aminoacyl-tRNA synthetases interact with the ribosome to recycle tRNAs.	Godinic-Mikulcic V, Jaric J, Greber BJ, Franke V, Hodnik V, Anderluh G, Ban N, Weygand-Durasevic I.	Nucleic Acids Res	10.1093/nar/gku164	2014
	Substrate-dependent transcriptomic shifts in Pelotomaculum thermopropionicum grown in syntrophic co-culture with Methanothermobacter thermautotrophicus.	Kato S, Kosaka T, Watanabe K.	Microb Biotechnol	10.1111/j.1751-7915.2009.00102.x	2009
Phylogeny	Biogas production using anaerobic groundwater containing a subterranean microbial community associated with the accretionary prism.	Baito K, Imai S, Matsushita M, Otani M, Sato Y, Kimura H.	Microb Biotechnol	10.1111/1751-7915.12179	2015
	Analysis of membrane stereochemistry with homology modeling of sn-glycerol-1-phosphate dehydrogenase.	Daiyasu H, Hiroike T, Koga Y, Toh H.	Protein Eng	10.1093/protein/15.12.987	2002
	TrpY regulation of trpB2 transcription in Methanothermobacter thermautotrophicus.	Karr EA, Sandman K, Lurz R, Reeve JN.	J Bacteriol	10.1128/jb.01926-07	2008
Metabolism	The Methanosarcina acetivorans thioredoxin system activates DNA binding of the redox-sensitive transcriptional regulator MsvR.	Sheehan R, McCarver AC, Isom CE, Karr EA, Lessner DJ.	J Ind Microbiol Biotechnol	10.1007/s10295-015-1592-y	2015
	Co-cultivation of Thermoanaerobacter strains with a methanogenic partner enhances glycerol conversion.	Magalhaes CP, Ribeiro JA, Guedes AP, Arantes AL, Sousa DZ, Stams AJM, Alves MM, Cavaleiro AJ.	Microb Biotechnol	10.1111/1751-7915.13506	2020
Metabolism	Application of pseudomurein endoisopeptidase to fluorescence in situ hybridization of methanogens within the family Methanobacteriaceae.	Nakamura K, Terada T, Sekiguchi Y, Shinzato N, Meng XY, Enoki M, Kamagata Y.	Appl Environ Microbiol	10.1128/aem.01499-06	2006
Enzymology	The anabolic pyruvate oxidoreductase from Methanococcus maripaludis.	Lin WC, Yang YL, Whitman WB.	Arch Microbiol	10.1007/s00203-003-0554-3	2003
Metabolism	Detection of novel syntrophic acetate-oxidizing bacteria from biogas processes by continuous acetate enrichment approaches.	Westerholm M, Muller B, Singh A, Karlsson Lindsjo O, Schnurer A.	Microb Biotechnol	10.1111/1751-7915.13035	2018
Metabolism	DNA binding by the Methanothermobacter thermautotrophicus Cdc6 protein is inhibited by the minichromosome maintenance helicase.	Kasiviswanathan R, Shin JH, Kelman Z.	J Bacteriol	10.1128/jb.00168-06	2006
Metabolism	Methanococci use the diaminopimelate aminotransferase (DapL) pathway for lysine biosynthesis.	Liu Y, White RH, Whitman WB.	J Bacteriol	10.1128/jb.00172-10	2010
	Rational design of an evolutionary precursor of glutaminyl-tRNA synthetase.	O'Donoghue P, Sheppard K, Nureki O, Soll D.	Proc Natl Acad Sci U S A	10.1073/pnas.1117294108	2011
	Diversity and Functional Analysis of the FeMo-Cofactor Maturase NifB.	Arragain S, Jimenez-Vicente E, Scandurra AA, Buren S, Rubio LM, Echavarri-Erasun C.	Front Plant Sci	10.3389/fpls.2017.01947	2017
Metabolism	Cysteine activation is an inherent in vitro property of prolyl-tRNA synthetases.	Ahel I, Stathopoulos C, Ambrogelly A, Sauerwald A, Toogood H, Hartsch T, Soll D.	J Biol Chem	10.1074/jbc.m206928200	2002
	Evaluation of synthetic formaldehyde and methanol assimilation pathways in Yarrowia lipolytica.	Vartiainen E, Blomberg P, Ilmen M, Andberg M, Toivari M, Penttila M.	Fungal Biol Biotechnol	10.1186/s40694-019-0090-9	2019
	Microbial Resource Management for Ex Situ Biomethanation of Hydrogen at Alkaline pH.	Logrono W, Popp D, Kleinsteuber S, Strauber H, Harms H, Nikolausz M.	Microorganisms	10.3390/microorganisms8040614	2020
Metabolism	Unusual Phosphoenolpyruvate (PEP) Synthetase-Like Protein Crucial to Enhancement of Polyhydroxyalkanoate Accumulation in Haloferax mediterranei Revealed by Dissection of PEP-Pyruvate Interconversion Mechanism.	Chen J, Mitra R, Zhang S, Zuo Z, Lin L, Zhao D, Xiang H, Han J.	Appl Environ Microbiol	10.1128/aem.00984-19	2019
	Evolutionary divergence of the archaeal aspartyl-tRNA synthetases into discriminating and nondiscriminating forms.	Tumbula-Hansen D, Feng L, Toogood H, Stetter KO, Soll D.	J Biol Chem	10.1074/jbc.m204767200	2002
	MetaMetaDB: a database and analytic system for investigating microbial habitability.	Yang CC, Iwasaki W.	PLoS One	10.1371/journal.pone.0087126	2014
	The chromosome copy number of the hyperthermophilic archaeon Thermococcus kodakarensis KOD1.	Spaans SK, van der Oost J, Kengen SW.	Extremophiles	10.1007/s00792-015-0750-5	2015
Metabolism	The One-carbon Carrier Methylofuran from Methylobacterium extorquens AM1 Contains a Large Number of alpha- and gamma-Linked Glutamic Acid Residues.	Hemmann JL, Saurel O, Ochsner AM, Stodden BK, Kiefer P, Milon A, Vorholt JA.	J Biol Chem	10.1074/jbc.m116.714741	2016
Metabolism	Genome-guided analysis of physiological and morphological traits of the fermentative acetate oxidizer Thermacetogenium phaeum.	Oehler D, Poehlein A, Leimbach A, Muller N, Daniel R, Gottschalk G, Schink B.	BMC Genomics	10.1186/1471-2164-13-723	2012
Metabolism	3'-5' tRNAHis guanylyltransferase in bacteria.	Heinemann IU, Randau L, Tomko RJ, Soll D.	FEBS Lett	10.1016/j.febslet.2010.07.023	2010
	Advances and Applications of Clostridium Co-culture Systems in Biotechnology.	Du Y, Zou W, Zhang K, Ye G, Yang J, Yang J.	Front Microbiol	10.3389/fmicb.2020.560223	2020
Metabolism	Structure and regulatory role of the C-terminal winged helix domain of the archaeal minichromosome maintenance complex.	Wiedemann C, Szambowska A, Hafner S, Ohlenschlager O, Guhrs KH, Gorlach M.	Nucleic Acids Res	10.1093/nar/gkv120	2015
	RNA degradation by the plant RNA exosome involves both phosphorolytic and hydrolytic activities.	Sikorska N, Zuber H, Gobert A, Lange H, Gagliardi D.	Nat Commun	10.1038/s41467-017-02066-2	2017
	Identification of a Ligand Binding Pocket in LdtR from Liberibacter asiaticus.	Pagliai FA, Gonzalez CF, Lorca GL.	Front Microbiol	10.3389/fmicb.2015.01314	2015
Metabolism	The carbonic anhydrase of Clostridium autoethanogenum represents a new subclass of beta-carbonic anhydrases.	Pander B, Harris G, Scott DJ, Winzer K, Kopke M, Simpson SD, Minton NP, Henstra AM.	Appl Microbiol Biotechnol	10.1007/s00253-019-10015-w	2019
	Towards a metagenomic understanding on enhanced biomethane production from waste activated sludge after pH 10 pretreatment.	Wong MT, Zhang D, Li J, Hui RK, Tun HM, Brar MS, Park TJ, Chen Y, Leung FC.	Biotechnol Biofuels	10.1186/1754-6834-6-38	2013
Metabolism	Lipid-protein interactions modulate the conformational equilibrium of a potassium channel.	Gu RX, de Groot BL.	Nat Commun	10.1038/s41467-020-15741-8	2020
	The isoprenoid alcohol pathway, a synthetic route for isoprenoid biosynthesis.	Clomburg JM, Qian S, Tan Z, Cheong S, Gonzalez R.	Proc Natl Acad Sci U S A	10.1073/pnas.1821004116	2019
	The membrane potential of Methanobacterium thermoautotrophicum under different external conditions.	Polak P, Smigan P, Greksak M.	Folia Microbiol (Praha)	10.1007/bf02817407	2000
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	Characterization of a Novel Thermostable DNA Lyase Used To Prepare DNA for Next-Generation Sequencing.	Baljinnyam T, Conrad JW, Sowers ML, Chang-Gu B, Herring JL, Hackfeld LC, Zhang K, Sowers LC.	Chem Res Toxicol	10.1021/acs.chemrestox.2c00172	2023
Metabolism	Methanogens with pseudomurein use diaminopimelate aminotransferase in lysine biosynthesis.	Graham DE, Huse HK.	FEBS Lett	10.1016/j.febslet.2008.03.021	2008
Metabolism	Structural and functional mapping of the archaeal multi-aminoacyl-tRNA synthetase complex.	Hausmann CD, Ibba M.	FEBS Lett	10.1016/j.febslet.2008.05.043	2008
Metabolism	The intrinsic DNA helicase activity of Methanobacterium thermoautotrophicum delta H minichromosome maintenance protein.	Shechter DF, Ying CY, Gautier J.	J Biol Chem	10.1074/jbc.m000398200	2000
Metabolism	Improving the catalytic activity of isopentenyl phosphate kinase through protein coevolution analysis.	Liu Y, Yan Z, Lu X, Xiao D, Jiang H.	Sci Rep	10.1038/srep24117	2016
Metabolism	A Ferredoxin- and F420H2-Dependent, Electron-Bifurcating, Heterodisulfide Reductase with Homologs in the Domains Bacteria and Archaea.	Yan Z, Wang M, Ferry JG.	mBio	10.1128/mbio.02285-16	2017
Metabolism	Prion protein regulates iron transport by functioning as a ferrireductase.	Singh A, Haldar S, Horback K, Tom C, Zhou L, Meyerson H, Singh N.	J Alzheimers Dis	10.3233/jad-130218	2013
	Stable and Variable Parts of Microbial Community in Siberian Deep Subsurface Thermal Aquifer System Revealed in a Long-Term Monitoring Study.	Frank YA, Kadnikov VV, Gavrilov SN, Banks D, Gerasimchuk AL, Podosokorskaya OA, Merkel AY, Chernyh NA, Mardanov AV, Ravin NV, Karnachuk OV, Bonch-Osmolovskaya EA.	Front Microbiol	10.3389/fmicb.2016.02101	2016
	The Catabolic System of Acetovanillone and Acetosyringone in Sphingobium sp. Strain SYK-6 Useful for Upgrading Aromatic Compounds Obtained through Chemical Lignin Depolymerization.	Higuchi Y, Kamimura N, Takenami H, Kikuiri Y, Yasuta C, Tanatani K, Shobuda T, Otsuka Y, Nakamura M, Sonoki T, Masai E.	Appl Environ Microbiol	10.1128/aem.00724-22	2022
Metabolism	Metabolic dependencies govern microbial syntrophies during methanogenesis in an anaerobic digestion ecosystem.	Zhu X, Campanaro S, Treu L, Seshadri R, Ivanova N, Kougias PG, Kyrpides N, Angelidaki I.	Microbiome	10.1186/s40168-019-0780-9	2020
	Efficient production of methane from artificial garbage waste by a cylindrical bioelectrochemical reactor containing carbon fiber textiles.	Sasaki D, Sasaki K, Watanabe A, Morita M, Igarashi Y, Ohmura N.	AMB Express	10.1186/2191-0855-3-17	2013
Metabolism	An archaeal glutamate decarboxylase homolog functions as an aspartate decarboxylase and is involved in beta-alanine and coenzyme A biosynthesis.	Tomita H, Yokooji Y, Ishibashi T, Imanaka T, Atomi H.	J Bacteriol	10.1128/jb.01327-13	2014
Metabolism	Mesophilic fermentation of renewable biomass: does hydraulic retention time regulate methanogen diversity?	Krakat N, Schmidt S, Scherer P.	Appl Environ Microbiol	10.1128/aem.00927-10	2010
	A redox trap to augment the intein toolbox.	Callahan BP, Stanger M, Belfort M.	Biotechnol Bioeng	10.1002/bit.24821	2013
	Biological iron-sulfur storage in a thioferrate-protein nanoparticle.	Vaccaro BJ, Clarkson SM, Holden JF, Lee DW, Wu CH, Poole Ii FL, Cotelesage JJH, Hackett MJ, Mohebbi S, Sun J, Li H, Johnson MK, George GN, Adams MWW.	Nat Commun	10.1038/ncomms16110	2017
	Atomistic ensemble modeling and small-angle neutron scattering of intrinsically disordered protein complexes: applied to minichromosome maintenance protein.	Krueger S, Shin JH, Raghunandan S, Curtis JE, Kelman Z.	Biophys J	10.1016/j.bpj.2011.11.006	2011
	Facilitation as Attenuating of Environmental Stress among Structured Microbial Populations.	Martins SC, Santaella ST, Martins CM, Martins RP.	ScientificWorldJournal	10.1155/2016/5713939	2016
Metabolism	The biosynthesis of the anti-microbial diterpenoid leubethanol in Leucophyllum frutescens proceeds via an all-cis prenyl intermediate.	Miller GP, Bhat WW, Lanier ER, Johnson SR, Mathieu DT, Hamberger B.	Plant J	10.1111/tpj.14957	2020
	Structure of an archaeal non-discriminating glutamyl-tRNA synthetase: a missing link in the evolution of Gln-tRNAGln formation.	Nureki O, O'Donoghue P, Watanabe N, Ohmori A, Oshikane H, Araiso Y, Sheppard K, Soll D, Ishitani R.	Nucleic Acids Res	10.1093/nar/gkq605	2010
Metabolism	Exploring natural biodiversity to expand access to microbial terpene synthesis.	Rico J, Duquesne K, Petit JL, Mariage A, Darii E, Peruch F, de Berardinis V, Iacazio G.	Microb Cell Fact	10.1186/s12934-019-1074-4	2019
Metabolism	Methanothermobacter thermautotrophicus tRNA Gln confines the amidotransferase GatCAB to asparaginyl-tRNA Asn formation.	Sheppard K, Sherrer RL, Soll D.	J Mol Biol	10.1016/j.jmb.2008.01.064	2008
Phylogeny	Computational Exploration of Putative LuxR Solos in Archaea and Their Functional Implications in Quorum Sensing.	Rajput A, Kumar M.	Front Microbiol	10.3389/fmicb.2017.00798	2017
Enzymology	Overexpression of the Arabidopsis and winter squash superoxide dismutase genes enhances chilling tolerance via ABA-sensitive transcriptional regulation in transgenic Arabidopsis.	Lin KH, Sei SC, Su YH, Chiang CM.	Plant Signal Behav	10.1080/15592324.2019.1685728	2019
	Characterizing the DNA Methyltransferases of Haloferax volcanii via Bioinformatics, Gene Deletion, and SMRT Sequencing.	Ouellette M, Gogarten JP, Lajoie J, Makkay AM, Papke RT.	Genes (Basel)	10.3390/genes9030129	2018
Metabolism	Mechanism of Archaeal MCM Helicase Recruitment to DNA Replication Origins.	Samson RY, Abeyrathne PD, Bell SD.	Mol Cell	10.1016/j.molcel.2015.12.005	2016
	Microbial interspecies interactions: recent findings in syntrophic consortia.	Kouzuma A, Kato S, Watanabe K.	Front Microbiol	10.3389/fmicb.2015.00477	2015
Enzymology	Structural studies of geranylgeranylglyceryl phosphate synthase, a prenyltransferase found in thermophilic Euryarchaeota.	Blank PN, Barnett AA, Barnett AA, Ronnebaum TA, Alderfer KE, Gillott BN, Christianson DW, Himmelberger JA.	Acta Crystallogr D Struct Biol	10.1107/s2059798320004878	2020
Stress	Hexamerization and thermostability emerged very early during geranylgeranylglyceryl phosphate synthase evolution.	Kropp C, Straub K, Linde M, Babinger P.	Protein Sci	10.1002/pro.4016	2021
Metabolism	Crystal structure of a 9-subunit archaeal exosome in pre-catalytic states of the phosphorolytic reaction.	Lorentzen E, Conti E.	Archaea	10.1155/2012/721869	2012
Genetics	Genome-Wide Identification and Expression Profiling of the PDI Gene Family Reveals Their Probable Involvement in Abiotic Stress Tolerance in Tomato (Solanum Lycopersicum L.).	Wai AH, Waseem M, Khan ABMMM, Nath UK, Lee DJ, Kim ST, Kim CK, Chung MY.	Genes (Basel)	10.3390/genes12010023	2020
Metabolism	Complete genome sequence of the genetically tractable hydrogenotrophic methanogen Methanococcus maripaludis.	Hendrickson EL, Kaul R, Zhou Y, Bovee D, Chapman P, Chung J, Conway de Macario E, Dodsworth JA, Gillett W, Graham DE, Hackett M, Haydock AK, Kang A, Land ML, Levy R, Lie TJ, Major TA, Moore BC, Porat I, Palmeiri A, Rouse G, Saenphimmachak C, Soll D, Van Dien S, Wang T, Whitman WB, Xia Q, Zhang Y, Larimer FW, Olson MV, Leigh JA.	J Bacteriol	10.1128/jb.186.20.6956-6969.2004	2004
Metabolism	The archaeal transamidosome for RNA-dependent glutamine biosynthesis.	Rampias T, Sheppard K, Soll D.	Nucleic Acids Res	10.1093/nar/gkq336	2010
Phylogeny	Distinct Distribution of Archaea From Soil to Freshwater to Estuary: Implications of Archaeal Composition and Function in Different Environments.	Wang H, Bier R, Zgleszewski L, Peipoch M, Omondi E, Mukherjee A, Chen F, Zhang C, Kan J.	Front Microbiol	10.3389/fmicb.2020.576661	2020
Metabolism	Operation of the CO dehydrogenase/acetyl coenzyme A pathway in both acetate oxidation and acetate formation by the syntrophically acetate-oxidizing bacterium Thermacetogenium phaeum.	Hattori S, Galushko AS, Kamagata Y, Schink B.	J Bacteriol	10.1128/jb.187.10.3471-3476.2005	2005
	Unraveling the microbiome of a thermophilic biogas plant by metagenome and metatranscriptome analysis complemented by characterization of bacterial and archaeal isolates.	Maus I, Koeck DE, Cibis KG, Hahnke S, Kim YS, Langer T, Kreubel J, Erhard M, Bremges A, Off S, Stolze Y, Jaenicke S, Goesmann A, Sczyrba A, Scherer P, Konig H, Schwarz WH, Zverlov VV, Liebl W, Puhler A, Schluter A, Klocke M.	Biotechnol Biofuels	10.1186/s13068-016-0581-3	2016
Metabolism	Characterization of an archaeal medium-chain acyl coenzyme A synthetase from Methanosarcina acetivorans.	Meng Y, Ingram-Smith C, Cooper LL, Smith KS.	J Bacteriol	10.1128/jb.00600-10	2010
Enzymology	Identification of an Archaeal type II isopentenyl diphosphate isomerase in methanothermobacter thermautotrophicus.	Barkley SJ, Cornish RM, Poulter CD.	J Bacteriol	10.1128/jb.186.6.1811-1817.2004	2004
Metabolism	Transcription by Methanothermobacter thermautotrophicus RNA polymerase in vitro releases archaeal transcription factor B but not TATA-box binding protein from the template DNA.	Xie Y, Reeve JN.	J Bacteriol	10.1128/jb.186.18.6306-6310.2004	2004
Metabolism	Lipid Anchoring of Archaeosortase Substrates and Midcell Growth in Haloarchaea.	Abdul-Halim MF, Schulze S, DiLucido A, Pfeiffer F, Bisson Filho AW, Pohlschroder M.	mBio	10.1128/mbio.00349-20	2020
	Characterization of a Methanogenic Community within an Algal Fed Anaerobic Digester.	Ellis JT, Tramp C, Sims RC, Miller CD.	ISRN Microbiol	10.5402/2012/753892	2012
Metabolism	Expression, purification and biochemical characterization of Schizosaccharomyces pombe Mcm4, 6 and 7.	Xu M, Chang YP, Chen XS.	BMC Biochem	10.1186/1471-2091-14-5	2013
Enzymology	The phosphoenolpyruvate carboxylase from Methanothermobacter thermautotrophicus has a novel structure.	Patel HM, Kraszewski JL, Mukhopadhyay B.	J Bacteriol	10.1128/jb.186.15.5129-5137.2004	2004
	Membrane Lipid Composition and Amino Acid Excretion Patterns of Methanothermococcus okinawensis Grown in the Presence of Inhibitors Detected in the Enceladian Plume.	Taubner RS, Baumann LMF, Bauersachs T, Clifford EL, Mahnert B, Reischl B, Seifert R, Peckmann J, Rittmann SKR, Birgel D.	Life (Basel)	10.3390/life9040085	2019
Metabolism	Modeling the Thermoproteaceae RNase P RNA.	Chan PP, Brown JW, Lowe TM.	RNA Biol	10.4161/rna.21502	2012
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Metabolism	Microbial and Genetic Resources for Cobalamin (Vitamin B12) Biosynthesis: From Ecosystems to Industrial Biotechnology.	Balabanova L, Averianova L, Marchenok M, Son O, Tekutyeva L.	Int J Mol Sci	10.3390/ijms22094522	2021
Metabolism	Anaerobic digestion of renewable biomass: thermophilic temperature governs methanogen population dynamics.	Krakat N, Westphal A, Schmidt S, Scherer P.	Appl Environ Microbiol	10.1128/aem.02397-09	2010
Enzymology	The presence of H+ and Na(+)-translocating ATPases in Methanobacterium thermoautotrophicum and their possible function under alkaline conditions.	Smigan P, Majernik A, Polak P, Hapala I, Greksak M.	FEBS Lett	10.1016/0014-5793(95)00866-8	1995
	The Heptameric SmAP1 and SmAP2 Proteins of the Crenarchaeon Sulfolobus Solfataricus Bind to Common and Distinct RNA Targets.	Martens B, Bezerra GA, Kreuter MJ, Grishkovskaya I, Manica A, Arkhipova V, Djinovic-Carugo K, Blasi U.	Life (Basel)	10.3390/life5021264	2015
Metabolism	Sequence Analysis and Comparative Study of the Protein Subunits of Archaeal RNase P.	Samanta MP, Lai SM, Daniels CJ, Gopalan V.	Biomolecules	10.3390/biom6020022	2016
Enzymology	Thermococcus Eurythermalis Endonuclease IV Can Cleave Various Apurinic/Apyrimidinic Site Analogues in ssDNA and dsDNA.	Wang WW, Zhou H, Xie JJ, Yi GS, He JH, Wang FP, Xiao X, Liu XP.	Int J Mol Sci	10.3390/ijms20010069	2018
	The Exploration of the Thermococcus barophilus Lipidome Reveals the Widest Variety of Phosphoglycolipids in Thermococcales.	Tourte M, Coffinet S, Wormer L, Lipp JS, Hinrichs KU, Oger PM.	Front Microbiol	10.3389/fmicb.2022.869479	2022
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Metabolism	Biochemical and phylogenetic analyses of phosphatidylinositol production in Angomonas deanei, an endosymbiont-harboring trypanosomatid.	de Azevedo-Martins AC, Alves JM, de Mello FG, Vasconcelos AT, de Souza W, Einicker-Lamas M, Motta MC.	Parasit Vectors	10.1186/s13071-015-0854-x	2015
Metabolism	Characterization of energy-conserving hydrogenase B in Methanococcus maripaludis.	Major TA, Liu Y, Whitman WB.	J Bacteriol	10.1128/jb.01446-09	2010
Biotechnology	Rational synthetic combination genetic devices boosting high temperature ethanol fermentation.	Sun H, Jia H, Li J, Feng X, Liu Y, Zhou X, Li C.	Synth Syst Biotechnol	10.1016/j.synbio.2017.04.003	2017
Enzymology	Crystal structure of a near-full-length archaeal MCM: functional insights for an AAA+ hexameric helicase.	Brewster AS, Wang G, Yu X, Greenleaf WB, Carazo JM, Tjajadi M, Klein MG, Chen XS.	Proc Natl Acad Sci U S A	10.1073/pnas.0808037105	2008
Proteome	Classification of the treble clef zinc finger: noteworthy lessons for structure and function evolution.	Kaur G, Subramanian S.	Sci Rep	10.1038/srep32070	2016
Pathogenicity	Assessment of the oxidant tolerance of Methanosarcina acetivorans.	Horne AJ, Lessner DJ.	FEMS Microbiol Lett	10.1111/1574-6968.12115	2013
Metabolism	Minichromosome maintenance helicase activity is controlled by N- and C-terminal motifs and requires the ATPase domain helix-2 insert.	Jenkinson ER, Chong JP.	Proc Natl Acad Sci U S A	10.1073/pnas.0509297103	2006
Enzymology	Minimal and RNA-free RNase P in Aquifex aeolicus.	Nickel AI, Waber NB, Gossringer M, Lechner M, Linne U, Toth U, Rossmanith W, Hartmann RK.	Proc Natl Acad Sci U S A	10.1073/pnas.1707862114	2017
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Genetics	The ring-shaped hexameric helicases that function at DNA replication forks.	O'Donnell ME, Li H.	Nat Struct Mol Biol	10.1038/s41594-018-0024-x	2018
Metabolism	Molecular analyses of a three-subunit euryarchaeal clamp loader complex from Methanosarcina acetivorans.	Chen YH, Lin Y, Yoshinaga A, Chhotani B, Lorenzini JL, Crofts AA, Mei S, Mackie RI, Ishino Y, Cann IK.	J Bacteriol	10.1128/jb.00414-09	2009
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Metabolism	Conformational changes in orotidine 5'-monophosphate decarboxylase: a structure-based explanation for how the 5'-phosphate group activates the enzyme.	Desai BJ, Wood BM, Fedorov AA, Fedorov EV, Goryanova B, Amyes TL, Richard JP, Almo SC, Gerlt JA.	Biochemistry	10.1021/bi301188k	2012
Metabolism	Molecular characterization of the thioredoxin system from Methanosarcina acetivorans.	McCarver AC, Lessner DJ.	FEBS J	10.1111/febs.12964	2014
Metabolism	Crystallographic snapshots of iterative substrate translocations during nicotianamine synthesis in Archaea.	Dreyfus C, Lemaire D, Mari S, Pignol D, Arnoux P.	Proc Natl Acad Sci U S A	10.1073/pnas.0904439106	2009
	X-ray structure of the complex of regulatory subunits of human DNA polymerase delta.	Baranovskiy AG, Babayeva ND, Liston VG, Rogozin IB, Koonin EV, Pavlov YI, Vassylyev DG, Tahirov TH.	Cell Cycle	10.4161/cc.7.19.6720	2008
Metabolism	Conformational flexibility and molecular interactions of an archaeal homologue of the Shwachman-Bodian-Diamond syndrome protein.	Ng CL, Waterman DG, Koonin EV, Walters AD, Chong JP, Isupov MN, Lebedev AA, Bunka DH, Stockley PG, Ortiz-Lombardia M, Antson AA.	BMC Struct Biol	10.1186/1472-6807-9-32	2009
Metabolism	An archaeal tRNA-synthetase complex that enhances aminoacylation under extreme conditions.	Godinic-Mikulcic V, Jaric J, Hausmann CD, Ibba M, Weygand-Durasevic I.	J Biol Chem	10.1074/jbc.m110.168526	2011
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Metabolism	Functional conservation of the pre-sensor one beta-finger hairpin (PS1-hp) structures in mini-chromosome maintenance proteins of Saccharomyces cerevisiae and archaea.	Ramey CJ, Sclafani RA.	G3 (Bethesda)	10.1534/g3.114.011668	2014
Metabolism	Cooperative RNP assembly: complementary rescue of structural defects by protein and RNA subunits of archaeal RNase P.	Chen WY, Xu Y, Cho IM, Oruganti SV, Foster MP, Gopalan V.	J Mol Biol	10.1016/j.jmb.2011.05.012	2011
Metabolism	Noteworthy Facts about a Methane-Producing Microbial Community Processing Acidic Effluent from Sugar Beet Molasses Fermentation.	Chojnacka A, Szczesny P, Blaszczyk MK, Zielenkiewicz U, Detman A, Salamon A, Sikora A.	PLoS One	10.1371/journal.pone.0128008	2015
Enzymology	Dual activity of PNGM-1 pinpoints the evolutionary origin of subclass B3 metallo-beta-lactamases: a molecular and evolutionary study.	Lee JH, Takahashi M, Jeon JH, Kang LW, Seki M, Park KS, Hong MK, Park YS, Kim TY, Karim AM, Lee JH, Nashimoto M, Lee SH.	Emerg Microbes Infect	10.1080/22221751.2019.1692638	2019
Metabolism	Structure and activity of a novel archaeal beta-CASP protein with N-terminal KH domains.	Silva AP, Chechik M, Byrne RT, Waterman DG, Ng CL, Dodson EJ, Koonin EV, Antson AA, Smits C.	Structure	10.1016/j.str.2011.03.002	2011
Metabolism	Analysis of propionate-degrading consortia from agricultural biogas plants.	Ahlert S, Zimmermann R, Ebling J, Konig H.	Microbiologyopen	10.1002/mbo3.386	2016
	Crystal structure of Mil (Mth680): internal duplication and similarity between the Imp4/Brix domain and the anticodon-binding domain of class IIa aminoacyl-tRNA synthetases.	Ng CL, Waterman D, Koonin EV, Antson AA, Ortiz-Lombardia M.	EMBO Rep	10.1038/sj.embor.7400328	2005
	Crystallization and preliminary X-ray diffraction analysis of the full-length Mg2+ transporter MgtE.	Hattori M, Tanaka Y, Fukai S, Ishitani R, Nureki O.	Acta Crystallogr Sect F Struct Biol Cryst Commun	10.1107/s1744309107032332	2007
Enzymology	Spectroscopic characterization of the alternate form of S-methylcoenzyme M reductase from Methanobacterium thermoautotrophicum (strain delta H).	Brenner MC, Ma L, Johnson MK, Scott RA.	Biochim Biophys Acta	10.1016/0167-4838(92)90264-e	1992
Genetics	DNA induces conformational changes in a recombinant human minichromosome maintenance complex.	Hesketh EL, Parker-Manuel RP, Chaban Y, Satti R, Coverley D, Orlova EV, Chong JP.	J Biol Chem	10.1074/jbc.m114.622738	2015
Metabolism	Mutations in subdomain B of the minichromosome maintenance (MCM) helicase affect DNA binding and modulate conformational transitions.	Jenkinson ER, Costa A, Leech AP, Patwardhan A, Onesti S, Chong JP.	J Biol Chem	10.1074/jbc.m806973200	2009
Metabolism	Characterization of a 45-kDa flavoprotein and evidence for a rubredoxin, two proteins that could participate in electron transport from H2 to CO2 in methanogenesis in Methanobacterium thermoautotrophicum.	Nolling J, Ishii M, Koch J, Pihl TD, Reeve JN, Thauer RK, Hedderich R.	Eur J Biochem	10.1111/j.1432-1033.1995.0628d.x	1995
	Regulation of tryptophan operon expression in the archaeon Methanothermobacter thermautotrophicus.	Xie Y, Reeve JN.	J Bacteriol	10.1128/jb.187.18.6419-6429.2005	2005
	X-ray structures of isopentenyl phosphate kinase.	Mabanglo MF, Schubert HL, Chen M, Hill CP, Poulter CD.	ACS Chem Biol	10.1021/cb100032g	2010
	Study of completed archaeal genomes and proteomes: hypothesis of strong mutational AT pressure existed in their common predecessor.	Khrustalev VV, Barkovsky EV.	Genomics Proteomics Bioinformatics	10.1016/s1672-0229(10)60003-4	2010
Metabolism	Microbial activity response to hydrogen injection in thermophilic anaerobic digesters revealed by genome-centric metatranscriptomics.	Fontana A, Kougias PG, Treu L, Kovalovszki A, Valle G, Cappa F, Morelli L, Angelidaki I, Campanaro S.	Microbiome	10.1186/s40168-018-0583-4	2018
Enzymology	Expression, purification and crystallization of an archaeal-type phosphoenolpyruvate carboxylase.	Dharmarajan L, Kraszewski JL, Mukhopadhyay B, Dunten PW.	Acta Crystallogr Sect F Struct Biol Cryst Commun	10.1107/s1744309109042663	2009
Enzymology	Coupling of DNA binding and helicase activity is mediated by a conserved loop in the MCM protein.	Sakakibara N, Kasiviswanathan R, Melamud E, Han M, Schwarz FP, Kelman Z.	Nucleic Acids Res	10.1093/nar/gkm1160	2008
Enzymology	Enzymatic degradation of cyclic 2,3-diphosphoglycerate to 2,3-diphosphoglycerate in Methanobacterium thermoautotrophicum.	Sastry MV, Robertson DE, Moynihan JA, Roberts MF.	Biochemistry	10.1021/bi00126a012	1992
	Characterization of the Cdc6 Homologues from the Euryarchaeon Thermoplasma acidophilum.	Haugland GT, Innselset M, Madern D, Birkeland NK.	Open Biochem J	10.2174/1874091x00802010129	2008
Metabolism	Non-autotrophic methanogens dominate in anaerobic digesters.	Kouzuma A, Tsutsumi M, Ishii S, Ueno Y, Abe T, Watanabe K.	Sci Rep	10.1038/s41598-017-01752-x	2017
Metabolism	Hjm/Hel308A DNA helicase from Sulfolobus tokodaii promotes replication fork regression and interacts with Hjc endonuclease in vitro.	Li Z, Lu S, Hou G, Ma X, Sheng D, Ni J, Shen Y.	J Bacteriol	10.1128/jb.01662-07	2008
Proteome	Realm of PD-(D/E)XK nuclease superfamily revisited: detection of novel families with modified transitive meta profile searches.	Knizewski L, Kinch LN, Grishin NV, Rychlewski L, Ginalski K.	BMC Struct Biol	10.1186/1472-6807-7-40	2007
Enzymology	Minimal Influence of [NiFe] Hydrogenase on Hydrogen Isotope Fractionation in H₂-Oxidizing Cupriavidus necator.	Campbell BJ, Sessions AL, Fox DN, Paul BG, Qin Q, Kellermann MY, Valentine DL.	Front Microbiol	10.3389/fmicb.2017.01886	2017
	Diversity and distribution of thermophilic hydrogenogenic carboxydotrophs revealed by microbial community analysis in sediments from multiple hydrothermal environments in Japan.	Omae K, Fukuyama Y, Yasuda H, Mise K, Yoshida T, Sako Y.	Arch Microbiol	10.1007/s00203-019-01661-9	2019
Metabolism	Isolation of a 5-hydroxybenzimidazolyl cobamide-containing enzyme involved in the methyltetrahydromethanopterin: coenzyme M methyltransferase reaction in Methanobacterium thermoautotrophicum.	Kengen SW, Daas PJ, Duits EF, Keltjens JT, van der Drift C, Vogels GD.	Biochim Biophys Acta	10.1016/0167-4838(92)90282-i	1992
Metabolism	The archaeal ATPase PINA interacts with the helicase Hjm via its carboxyl terminal KH domain remodeling and processing replication fork and Holliday junction.	Zhai B, DuPrez K, Han X, Yuan Z, Ahmad S, Xu C, Gu L, Ni J, Fan L, Shen Y.	Nucleic Acids Res	10.1093/nar/gky451	2018
	Activity-Based Protein Profiling for the Identification of Novel Carbohydrate-Active Enzymes Involved in Xylan Degradation in the Hyperthermophilic Euryarchaeon Thermococcus sp. Strain 2319x1E.	Klaus T, Ninck S, Albersmeier A, Busche T, Wibberg D, Jiang J, Elcheninov AG, Zayulina KS, Kaschani F, Brasen C, Overkleeft HS, Kalinowski J, Kublanov IV, Kaiser M, Siebers B.	Front Microbiol	10.3389/fmicb.2021.734039	2021
Enzymology	AMP-forming acetyl-CoA synthetases in Archaea show unexpected diversity in substrate utilization.	Ingram-Smith C, Smith KS.	Archaea	10.1155/2006/738517	2007
Genetics	Genome Analysis of Vallitalea guaymasensis Strain L81 Isolated from a Deep-Sea Hydrothermal Vent System.	Schouw A, Vulcano F, Roalkvam I, Hocking WP, Reeves E, Stokke R, Bodtker G, Steen IH.	Microorganisms	10.3390/microorganisms6030063	2018
	Cloning, Purification, and Partial Characterization of the Halobacterium sp. NRC-1 Minichromosome Maintenance (MCM) Helicase.	Sakakibara N, Han M, Rollor CR, Gilson RC, Busch C, Heo G, Kelman Z.	Open Microbiol J	10.2174/1874285800802010013	2008
Metabolism	Functional Interactions of Ribosomal Intersubunit Bridges in Saccharomyces cerevisiae.	Tamm T, Kisly I, Remme J.	Genetics	10.1534/genetics.119.302777	2019
Metabolism	Cytosolic lipid droplets as engineered organelles for production and accumulation of terpenoid biomaterials in leaves.	Sadre R, Kuo P, Chen J, Yang Y, Banerjee A, Benning C, Hamberger B.	Nat Commun	10.1038/s41467-019-08515-4	2019
Enzymology	Thermodynamic and Kinetic Response of Microbial Reactions to High CO₂.	Jin Q, Kirk MF.	Front Microbiol	10.3389/fmicb.2016.01696	2016
Metabolism	An aminoacyl-tRNA synthetase:elongation factor complex for substrate channeling in archaeal translation.	Hausmann CD, Praetorius-Ibba M, Ibba M.	Nucleic Acids Res	10.1093/nar/gkm534	2007
Metabolism	Improved orthologous databases to ease protozoan targets inference.	Kotowski N, Jardim R, Davila AM.	Parasit Vectors	10.1186/s13071-015-1090-0	2015
Enzymology	Structural basis of the Methanothermobacter thermautotrophicus MCM helicase activity.	Costa A, Pape T, van Heel M, Brick P, Patwardhan A, Onesti S.	Nucleic Acids Res	10.1093/nar/gkl708	2006
Metabolism	Stimulation of the methylcoenzyme M reduction by uridine-5'-diphospho-sugars in cell-free extracts of Methanobacterium thermoautotrophicum (strain delta H).	Keltjens JT, Kraft HJ, Damen WG, van der Drift C, Vogels GD.	Eur J Biochem	10.1111/j.1432-1033.1989.tb15031.x	1989
Metabolism	Anaerobic degradation of xenobiotic isophthalate by the fermenting bacterium Syntrophorhabdus aromaticivorans.	Junghare M, Spiteller D, Schink B.	ISME J	10.1038/s41396-019-0348-5	2019
Enzymology	Inhibition of homologous phosphorolytic ribonucleases by citrate may represent an evolutionarily conserved communicative link between RNA degradation and central metabolism.	Stone CM, Butt LE, Bufton JC, Lourenco DC, Gowers DM, Pickford AR, Cox PA, Vincent HA, Callaghan AJ.	Nucleic Acids Res	10.1093/nar/gkx114	2017
	Comparative Analysis of the Microbiota Between Sheep Rumen and Rabbit Cecum Provides New Insight Into Their Differential Methane Production.	Mi L, Yang B, Hu X, Luo Y, Liu J, Yu Z, Wang J.	Front Microbiol	10.3389/fmicb.2018.00575	2018
	Roles of thermophilic thiosulfate-reducing bacteria and methanogenic archaea in the biocorrosion of oil pipelines.	Liang R, Grizzle RS, Duncan KE, McInerney MJ, Suflita JM.	Front Microbiol	10.3389/fmicb.2014.00089	2014
	Atomic resolution structure of the orotidine 5'-monophosphate decarboxylase product complex combined with surface plasmon resonance analysis: implications for the catalytic mechanism.	Fujihashi M, Mito K, Pai EF, Miki K.	J Biol Chem	10.1074/jbc.m112.427252	2013
Metabolism	An intertwined evolutionary history of methanogenic archaea and sulfate reduction.	Susanti D, Mukhopadhyay B.	PLoS One	10.1371/journal.pone.0045313	2012
Metabolism	Cys-tRNACys formation and cysteine biosynthesis in methanogenic archaea: two faces of the same problem?	Ambrogelly A, Kamtekar S, Sauerwald A, Ruan B, Tumbula-Hansen D, Kennedy D, Ahel I, Soll D.	Cell Mol Life Sci	10.1007/s00018-004-4194-9	2004
Metabolism	Global responses of Methanococcus maripaludis to specific nutrient limitations and growth rate.	Hendrickson EL, Liu Y, Rosas-Sandoval G, Porat I, Soll D, Whitman WB, Leigh JA.	J Bacteriol	10.1128/jb.01805-07	2008
Metabolism	Characterization of the replication initiator Orc1/Cdc6 from the Archaeon Picrophilus torridus.	Arora J, Goswami K, Saha S.	J Bacteriol	10.1128/jb.01020-13	2014
Proteome	ir-HSP: Improved Recognition of Heat Shock Proteins, Their Families and Sub-types Based On g-Spaced Di-peptide Features and Support Vector Machine.	Meher PK, Sahu TK, Gahoi S, Rao AR.	Front Genet	10.3389/fgene.2017.00235	2017
	Synthetic microcin C analogs targeting different aminoacyl-tRNA synthetases.	Van de Vijver P, Vondenhoff GH, Kazakov TS, Semenova E, Kuznedelov K, Metlitskaya A, Van Aerschot A, Severinov K.	J Bacteriol	10.1128/jb.00829-09	2009
Metabolism	Unusual Butane- and Pentanetriol-Based Tetraether Lipids in Methanomassiliicoccus luminyensis, a Representative of the Seventh Order of Methanogens.	Becker KW, Elling FJ, Yoshinaga MY, Sollinger A, Urich T, Hinrichs KU.	Appl Environ Microbiol	10.1128/aem.00772-16	2016
Enzymology	Determination of the amino acid sequence requirements for catalysis by the highly proficient orotidine monophosphate decarboxylase.	Yuan J, Cardenas AM, Gilbert HF, Palzkill T.	Protein Sci	10.1002/pro.728	2011
	Transcription by an archaeal RNA polymerase is slowed but not blocked by an archaeal nucleosome.	Xie Y, Reeve JN.	J Bacteriol	10.1128/jb.186.11.3492-3498.2004	2004
Metabolism	Product deuterium isotope effects for orotidine 5'-monophosphate decarboxylase: effect of changing substrate and enzyme structure on the partitioning of the vinyl carbanion reaction intermediate.	Toth K, Amyes TL, Wood BM, Chan K, Gerlt JA, Richard JP.	J Am Chem Soc	10.1021/ja102408k	2010
Metabolism	Role of motif III in catalysis by acetyl-CoA synthetase.	Ingram-Smith C, Thurman JL, Zimowski K, Smith KS.	Archaea	10.1155/2012/509579	2012
Enzymology	The magnetic and electronic properties of Methanobacterium thermoautotrophicum (strain delta H) methyl coenzyme M reductase and its nickel tetrapyrrole cofactor F430. A low temperature magnetic circular dichroism study.	Hamilton CL, Scott RA, Johnson MK.	J Biol Chem	10.1016/s0021-9258(18)80106-5	1989
Metabolism	Inorganic pyrophosphate synthesis during methanogenesis from methylcoenzyme M by cell-free extracts of Methanobacterium thermoautotrophicum (strain delta H).	Keltjens JT, van Erp R, Mooijaart RJ, van der Drift C, Vogels GD.	Eur J Biochem	10.1111/j.1432-1033.1988.tb13912.x	1988
Metabolism	Archaeal phospholipid biosynthetic pathway reconstructed in Escherichia coli.	Yokoi T, Isobe K, Yoshimura T, Hemmi H.	Archaea	10.1155/2012/438931	2012
Metabolism	Genome sequence of a mesophilic hydrogenotrophic methanogen Methanocella paludicola, the first cultivated representative of the order Methanocellales.	Sakai S, Takaki Y, Shimamura S, Sekine M, Tajima T, Kosugi H, Ichikawa N, Tasumi E, Hiraki AT, Shimizu A, Kato Y, Nishiko R, Mori K, Fujita N, Imachi H, Takai K.	PLoS One	10.1371/journal.pone.0022898	2011
Metabolism	Carbon-dependent control of electron transfer and central carbon pathway genes for methane biosynthesis in the Archaean, Methanosarcina acetivorans strain C2A.	Rohlin L, Gunsalus RP.	BMC Microbiol	10.1186/1471-2180-10-62	2010
Enzymology	Association of a multi-synthetase complex with translating ribosomes in the archaeon Thermococcus kodakarensis.	Raina M, Elgamal S, Santangelo TJ, Ibba M.	FEBS Lett	10.1016/j.febslet.2012.05.039	2012
	Association between Archaeal prolyl- and leucyl-tRNA synthetases enhances tRNA(Pro) aminoacylation.	Praetorius-Ibba M, Rogers TE, Samson R, Kelman Z, Ibba M.	J Biol Chem	10.1074/jbc.m503539200	2005
Enzymology	In vivo activation of methyl-coenzyme M reductase by carbon monoxide.	Zhou Y, Dorchak AE, Ragsdale SW.	Front Microbiol	10.3389/fmicb.2013.00069	2013
Enzymology	8-Hydroxy-5-deazaflavin-reducing hydrogenase from Methanobacterium thermoautotrophicum: 1. Purification and characterization.	Fox JA, Livingston DJ, Orme-Johnson WH, Walsh CT.	Biochemistry	10.1021/bi00388a007	1987
Enzymology	The predatory bacterium Bdellovibrio bacteriovorus aspartyl-tRNA synthetase recognizes tRNAAsn as a substrate.	Alperstein A, Ulrich B, Garofalo DM, Dreisbach R, Raff H, Sheppard K.	PLoS One	10.1371/journal.pone.0110842	2014
Metabolism	Cryo-EM structure of the archaeal 50S ribosomal subunit in complex with initiation factor 6 and implications for ribosome evolution.	Greber BJ, Boehringer D, Godinic-Mikulcic V, Crnkovic A, Ibba M, Weygand-Durasevic I, Ban N.	J Mol Biol	10.1016/j.jmb.2012.01.018	2012
Metabolism	Ribosomal intergenic spacer analysis as a tool for monitoring methanogenic Archaea changes in an anaerobic digester.	Ciesielski S, Bulkowska K, Dabrowska D, Kaczmarczyk D, Kowal P, Mozejko J.	Curr Microbiol	10.1007/s00284-013-0353-2	2013
	Protein function annotation with Structurally Aligned Local Sites of Activity (SALSAs).	Wang Z, Yin P, Lee JS, Parasuram R, Somarowthu S, Ondrechen MJ.	BMC Bioinformatics	10.1186/1471-2105-14-s3-s13	2013
Genetics	Comparative genomics reveals conserved positioning of essential genomic clusters in highly rearranged Thermococcales chromosomes.	Cossu M, Da Cunha V, Toffano-Nioche C, Forterre P, Oberto J.	Biochimie	10.1016/j.biochi.2015.07.008	2015
	Occurrence and expression of novel methyl-coenzyme M reductase gene (mcrA) variants in hot spring sediments.	McKay LJ, Hatzenpichler R, Inskeep WP, Fields MW.	Sci Rep	10.1038/s41598-017-07354-x	2017
	Mechanism of the orotidine 5'-monophosphate decarboxylase-catalyzed reaction: evidence for substrate destabilization.	Chan KK, Wood BM, Fedorov AA, Fedorov EV, Imker HJ, Amyes TL, Richard JP, Almo SC, Gerlt JA.	Biochemistry	10.1021/bi900623r	2009
Metabolism	Engineering of functional replication protein a homologs based on insights into the evolution of oligonucleotide/oligosaccharide-binding folds.	Lin Y, Lin LJ, Sriratana P, Coleman K, Ha T, Spies M, Cann IK.	J Bacteriol	10.1128/jb.01930-07	2008
Metabolism	Analyses of soil microbial community compositions and functional genes reveal potential consequences of natural forest succession.	Cong J, Yang Y, Liu X, Lu H, Liu X, Zhou J, Li D, Yin H, Ding J, Zhang Y.	Sci Rep	10.1038/srep10007	2015
	The Proteome and Lipidome of Thermococcus kodakarensis across the Stationary Phase.	Gagen EJ, Yoshinaga MY, Garcia Prado F, Hinrichs KU, Thomm M.	Archaea	10.1155/2016/5938289	2016
Metabolism	Isolation, crystallization and preliminary X-ray analysis of the transamidosome, a ribonucleoprotein involved in asparagine formation.	Bailly M, Blaise M, Lorber B, Thirup S, Kern D.	Acta Crystallogr Sect F Struct Biol Cryst Commun	10.1107/s1744309109015000	2009
Metabolism	Cleavage of model substrates by archaeal RNase P: role of protein cofactors in cleavage-site selection.	Sinapah S, Wu S, Chen Y, Pettersson BM, Gopalan V, Kirsebom LA.	Nucleic Acids Res	10.1093/nar/gkq732	2011
	A Genetic System for Methanocaldococcus jannaschii: An Evolutionary Deeply Rooted Hyperthermophilic Methanarchaeon.	Susanti D, Frazier MC, Mukhopadhyay B.	Front Microbiol	10.3389/fmicb.2019.01256	2019
Metabolism	The minichromosome maintenance replicative helicase.	Bell SD, Botchan MR.	Cold Spring Harb Perspect Biol	10.1101/cshperspect.a012807	2013
	Structure of the prolyl-tRNA synthetase from the eukaryotic pathogen Giardia lamblia.	Larson ET, Kim JE, Napuli AJ, Verlinde CL, Fan E, Zucker FH, Van Voorhis WC, Buckner FS, Hol WG, Merritt EA.	Acta Crystallogr D Biol Crystallogr	10.1107/s0907444912024699	2012
Metabolism	TM0486 from the hyperthermophilic anaerobe Thermotoga maritima is a thiamin-binding protein involved in response of the cell to oxidative conditions.	Dermoun Z, Foulon A, Miller MD, Harrington DJ, Deacon AM, Sebban-Kreuzer C, Roche P, Lafitte D, Bornet O, Wilson IA, Dolla A.	J Mol Biol	10.1016/j.jmb.2010.05.014	2010
Metabolism	A biosynthetic pathway for BE-7585A, a 2-thiosugar-containing angucycline-type natural product.	Sasaki E, Ogasawara Y, Liu HW.	J Am Chem Soc	10.1021/ja1014037	2010
Metabolism	Dynamic transition of a methanogenic population in response to the concentration of volatile fatty acids in a thermophilic anaerobic digester.	Hori T, Haruta S, Ueno Y, Ishii M, Igarashi Y.	Appl Environ Microbiol	10.1128/aem.72.2.1623-1630.2006	2006
Metabolism	Physiological and molecular characterizations of the interactions in two cellulose-to-methane cocultures.	Lu H, Ng SK, Jia Y, Cai M, Lee PKH.	Biotechnol Biofuels	10.1186/s13068-017-0719-y	2017
Metabolism	Characterization of two methanopterin biosynthesis mutants of Methylobacterium extorquens AM1 by use of a tetrahydromethanopterin bioassay.	Rasche ME, Havemann SA, Rosenzvaig M.	J Bacteriol	10.1128/jb.186.5.1565-1570.2004	2004
Enzymology	A study of archaeal enzymes involved in polar lipid synthesis linking amino acid sequence information, genomic contexts and lipid composition.	Daiyasu H, Kuma K, Yokoi T, Morii H, Koga Y, Toh H.	Archaea	10.1155/2005/452563	2005
Metabolism	Thioredoxin targets fundamental processes in a methane-producing archaeon, Methanocaldococcus jannaschii.	Susanti D, Wong JH, Vensel WH, Loganathan U, DeSantis R, Schmitz RA, Balsera M, Buchanan BB, Mukhopadhyay B.	Proc Natl Acad Sci U S A	10.1073/pnas.1324240111	2014
Metabolism	Quantitative Metaproteomics Highlight the Metabolic Contributions of Uncultured Phylotypes in a Thermophilic Anaerobic Digester.	Hagen LH, Frank JA, Zamanzadeh M, Eijsink VGH, Pope PB, Horn SJ, Arntzen MO.	Appl Environ Microbiol	10.1128/aem.01955-16	2017
Genetics	A manual curation strategy to improve genome annotation: application to a set of haloarchael genomes.	Pfeiffer F, Oesterhelt D.	Life (Basel)	10.3390/life5021427	2015
Metabolism	Cysteinyl-tRNA(Cys) formation in Methanocaldococcus jannaschii: the mechanism is still unknown.	Ruan B, Nakano H, Tanaka M, Mills JA, DeVito JA, Min B, Low KB, Battista JR, Soll D.	J Bacteriol	10.1128/jb.186.1.8-14.2004	2004
Metabolism	The structural basis of cysteine aminoacylation of tRNAPro by prolyl-tRNA synthetases.	Kamtekar S, Kennedy WD, Wang J, Stathopoulos C, Soll D, Steitz TA.	Proc Natl Acad Sci U S A	10.1073/pnas.0437911100	2003
	Genome-scale analysis of gene function in the hydrogenotrophic methanogenic archaeon Methanococcus maripaludis.	Sarmiento F, Mrazek J, Whitman WB.	Proc Natl Acad Sci U S A	10.1073/pnas.1220225110	2013
Genetics	Genome copy numbers and gene conversion in methanogenic archaea.	Hildenbrand C, Stock T, Lange C, Rother M, Soppa J.	J Bacteriol	10.1128/jb.01016-10	2011
	Crystal structures of two active proliferating cell nuclear antigens (PCNAs) encoded by Thermococcus kodakaraensis.	Ladner JE, Pan M, Hurwitz J, Kelman Z.	Proc Natl Acad Sci U S A	10.1073/pnas.1019179108	2011
Metabolism	Effects of H2 and formate on growth yield and regulation of methanogenesis in Methanococcus maripaludis.	Costa KC, Yoon SH, Pan M, Burn JA, Baliga NS, Leigh JA.	J Bacteriol	10.1128/jb.02141-12	2013
	Biosynthesis of threonylcarbamoyl adenosine (t6A), a universal tRNA nucleoside.	Deutsch C, El Yacoubi B, de Crecy-Lagard V, Iwata-Reuyl D.	J Biol Chem	10.1074/jbc.m112.344028	2012
Metabolism	A genetically engineered protein domain binding to bacterial murein, archaeal pseudomurein, and fungal chitin cell wall material.	Visweswaran GR, Dijkstra BW, Kok J.	Appl Microbiol Biotechnol	10.1007/s00253-012-3871-0	2012
Metabolism	Ancient translation factor is essential for tRNA-dependent cysteine biosynthesis in methanogenic archaea.	Liu Y, Nakamura A, Nakazawa Y, Asano N, Ford KA, Hohn MJ, Tanaka I, Yao M, Soll D.	Proc Natl Acad Sci U S A	10.1073/pnas.1411267111	2014
Metabolism	Dissecting functional cooperation among protein subunits in archaeal RNase P, a catalytic ribonucleoprotein complex.	Chen WY, Pulukkunat DK, Cho IM, Tsai HY, Gopalan V.	Nucleic Acids Res	10.1093/nar/gkq668	2010
Metabolism	Expanding tRNA recognition of a tRNA synthetase by a single amino acid change.	Feng L, Tumbula-Hansen D, Toogood H, Soll D.	Proc Natl Acad Sci U S A	10.1073/pnas.0631525100	2003
Metabolism	Molecular hydrogen is involved in phytohormone signaling and stress responses in plants.	Zeng J, Zhang M, Sun X.	PLoS One	10.1371/journal.pone.0071038	2013
	Browsing repeats in genomes: Pygram and an application to non-coding region analysis.	Durand P, Mahe F, Valin AS, Nicolas J.	BMC Bioinformatics	10.1186/1471-2105-7-477	2006
Genetics	Metagenomic profiles of free-living archaea, bacteria and small eukaryotes in coastal areas of Sichang island, Thailand.	Somboonna N, Assawamakin A, Wilantho A, Tangphatsornruang S, Tongsima S.	BMC Genomics	10.1186/1471-2164-13-s7-s29	2012
Genetics	Genomic characterization of methanomicrobiales reveals three classes of methanogens.	Anderson I, Ulrich LE, Lupa B, Susanti D, Porat I, Hooper SD, Lykidis A, Sieprawska-Lupa M, Dharmarajan L, Goltsman E, Lapidus A, Saunders E, Han C, Land M, Lucas S, Mukhopadhyay B, Whitman WB, Woese C, Bristow J, Kyrpides N.	PLoS One	10.1371/journal.pone.0005797	2009
Metabolism	A family of metal-dependent phosphatases implicated in metabolite damage-control.	Huang L, Khusnutdinova A, Nocek B, Brown G, Xu X, Cui H, Petit P, Flick R, Zallot R, Balmant K, Ziemak MJ, Shanklin J, de Crecy-Lagard V, Fiehn O, Gregory JF, Joachimiak A, Savchenko A, Yakunin AF, Hanson AD.	Nat Chem Biol	10.1038/nchembio.2108	2016
Metabolism	H2-independent growth of the hydrogenotrophic methanogen Methanococcus maripaludis.	Costa KC, Lie TJ, Jacobs MA, Leigh JA.	mBio	10.1128/mbio.00062-13	2013
	Campylobacter jejuni adenosine triphosphate phosphoribosyltransferase is an active hexamer that is allosterically controlled by the twisting of a regulatory tail.	Mittelstadt G, Moggre GJ, Panjikar S, Nazmi AR, Parker EJ.	Protein Sci	10.1002/pro.2948	2016
Metabolism	Uracil in duplex DNA is a substrate for the nucleotide incision repair pathway in human cells.	Prorok P, Alili D, Saint-Pierre C, Gasparutto D, Zharkov DO, Ishchenko AA, Tudek B, Saparbaev MK.	Proc Natl Acad Sci U S A	10.1073/pnas.1305624110	2013
Metabolism	Identification in Haloferax volcanii of phosphomevalonate decarboxylase and isopentenyl phosphate kinase as catalysts of the terminal enzyme reactions in an archaeal alternate mevalonate pathway.	Vannice JC, Skaff DA, Keightley A, Addo JK, Wyckoff GJ, Miziorko HM.	J Bacteriol	10.1128/jb.01230-13	2014
Metabolism	Use of a restriction enzyme-digested PCR product as substrate for helicase assays.	Shin JH, Reeve JN, Kelman Z.	Nucleic Acids Res	10.1093/nar/gni009	2005
Metabolism	Acyl homoserine lactone-based quorum sensing in a methanogenic archaeon.	Zhang G, Zhang F, Ding G, Li J, Guo X, Zhu J, Zhou L, Cai S, Liu X, Luo Y, Zhang G, Shi W, Dong X.	ISME J	10.1038/ismej.2011.203	2012
Enzymology	Two distinct regions in Staphylococcus aureus GatCAB guarantee accurate tRNA recognition.	Nakamura A, Sheppard K, Yamane J, Yao M, Soll D, Tanaka I.	Nucleic Acids Res	10.1093/nar/gkp955	2010
Phylogeny	Archaeal phylogeny based on proteins of the transcription and translation machineries: tackling the Methanopyrus kandleri paradox.	Brochier C, Forterre P, Gribaldo S.	Genome Biol	10.1186/gb-2004-5-3-r17	2004
	Effect of UV irradiation on Sulfolobus acidocaldarius and involvement of the general transcription factor TFB3 in the early UV response.	Schult F, Le TN, Albersmeier A, Rauch B, Blumenkamp P, van der Does C, Goesmann A, Kalinowski J, Albers SV, Siebers B.	Nucleic Acids Res	10.1093/nar/gky527	2018
	Methanosarcina Spherical Virus, a Novel Archaeal Lytic Virus Targeting Methanosarcina Strains.	Weidenbach K, Nickel L, Neve H, Alkhnbashi OS, Kunzel S, Kupczok A, Bauersachs T, Cassidy L, Tholey A, Backofen R, Schmitz RA.	J Virol	10.1128/jvi.00955-17	2017
Enzymology	Assembly of the complex between archaeal RNase P proteins RPP30 and Pop5.	Crowe BL, Bohlen CJ, Wilson RC, Gopalan V, Foster MP.	Archaea	10.1155/2011/891531	2011
	The L7Ae protein binds to two kink-turns in the Pyrococcus furiosus RNase P RNA.	Lai SM, Lai LB, Foster MP, Gopalan V.	Nucleic Acids Res	10.1093/nar/gku994	2014
Metabolism	DNA unwinding assay using streptavidin-bound oligonucleotides.	Shin JH, Kelman Z.	BMC Mol Biol	10.1186/1471-2199-7-43	2006
Metabolism	Structure, function, and evolution of the tRNA endonucleases of Archaea: an example of subfunctionalization.	Tocchini-Valentini GD, Fruscoloni P, Tocchini-Valentini GP.	Proc Natl Acad Sci U S A	10.1073/pnas.0502350102	2005
	Mechanisms for initiating cellular DNA replication.	Costa A, Hood IV, Berger JM.	Annu Rev Biochem	10.1146/annurev-biochem-052610-094414	2013
Metabolism	Response of a rice paddy soil methanogen to syntrophic growth as revealed by transcriptional analyses.	Liu P, Yang Y, Lu Z, Lu Y.	Appl Environ Microbiol	10.1128/aem.01259-14	2014
Metabolism	Conversion of NO2 to NO by reduced coenzyme F420 protects mycobacteria from nitrosative damage.	Purwantini E, Mukhopadhyay B.	Proc Natl Acad Sci U S A	10.1073/pnas.0812883106	2009
Metabolism	Assays for transfer RNA-dependent amino acid biosynthesis.	Sheppard K, Akochy PM, Soll D.	Methods	10.1016/j.ymeth.2007.06.010	2008
Metabolism	Crystal Structures of SgcE6 and SgcC, the Two-Component Monooxygenase That Catalyzes Hydroxylation of a Carrier Protein-Tethered Substrate during the Biosynthesis of the Enediyne Antitumor Antibiotic C-1027 in Streptomyces globisporus.	Chang CY, Lohman JR, Cao H, Tan K, Rudolf JD, Ma M, Xu W, Bingman CA, Yennamalli RM, Bigelow L, Babnigg G, Yan X, Joachimiak A, Phillips GN, Shen B.	Biochemistry	10.1021/acs.biochem.6b00713	2016
Metabolism	Growth-Phase-Specific Modulation of Cell Morphology and Gene Expression by an Archaeal Histone Protein.	Dulmage KA, Todor H, Schmid AK.	mBio	10.1128/mbio.00649-15	2015
Metabolism	Syntrophic oxidation of propionate in rice field soil at 15 and 30°C under methanogenic conditions.	Gan Y, Qiu Q, Liu P, Rui J, Lu Y.	Appl Environ Microbiol	10.1128/aem.00688-12	2012
Enzymology	Elucidating the process of activation of methyl-coenzyme M reductase.	Prakash D, Wu Y, Suh SJ, Duin EC.	J Bacteriol	10.1128/jb.01658-14	2014
Metabolism	Characterization of biochemical properties of an apurinic/apyrimidinic endonuclease from Helicobacter pylori.	Turgimbayeva A, Abeldenov S, Zharkov DO, Ishchenko AA, Ramankulov Y, Saparbaev M, Khassenov B.	PLoS One	10.1371/journal.pone.0202232	2018
Metabolism	Anaerobic coculture of microalgae with Thermosipho globiformans and Methanocaldococcus jannaschii at 68°C enhances generation of n-alkane-rich biofuels after pyrolysis.	Yamane K, Matsuyama S, Igarashi K, Utsumi M, Shiraiwa Y, Kuwabara T.	Appl Environ Microbiol	10.1128/aem.01685-12	2013
Metabolism	Towards a computational model of a methane producing archaeum.	Peterson JR, Labhsetwar P, Ellermeier JR, Kohler PR, Jain A, Ha T, Metcalf WW, Luthey-Schulten Z.	Archaea	10.1155/2014/898453	2014
Genetics	Diversity and Evolution of Type IV pili Systems in Archaea.	Makarova KS, Koonin EV, Albers SV.	Front Microbiol	10.3389/fmicb.2016.00667	2016
Metabolism	Evolution of multiple, mutually orthogonal prolyl-tRNA synthetase/tRNA pairs for unnatural amino acid mutagenesis in Escherichia coli.	Chatterjee A, Xiao H, Schultz PG.	Proc Natl Acad Sci U S A	10.1073/pnas.1212454109	2012
Proteome	Charge segregation and low hydrophobicity are key features of ribosomal proteins from different organisms.	Fedyukina DV, Jennaro TS, Cavagnero S.	J Biol Chem	10.1074/jbc.m113.507707	2014
Metabolism	First archaeal inorganic polyphosphate/ATP-dependent NAD kinase, from hyperthermophilic archaeon Pyrococcus horikoshii: cloning, expression, and characterization.	Sakuraba H, Kawakami R, Ohshima T.	Appl Environ Microbiol	10.1128/aem.71.8.4352-4358.2005	2005
	Heat shock response of Archaeoglobus fulgidus.	Rohlin L, Trent JD, Salmon K, Kim U, Gunsalus RP, Liao JC.	J Bacteriol	10.1128/jb.187.17.6046-6057.2005	2005
Metabolism	Recognition of tRNAGln by Helicobacter pylori GluRS2--a tRNAGln-specific glutamyl-tRNA synthetase.	Chang KM, Hendrickson TL.	Nucleic Acids Res	10.1093/nar/gkp754	2009
Metabolism	Archaeal ubiquitin-like proteins: functional versatility and putative ancestral involvement in tRNA modification revealed by comparative genomic analysis.	Makarova KS, Koonin EV.	Archaea	10.1155/2010/710303	2010
	Archaeal intrinsic transcription termination in vivo.	Santangelo TJ, Cubonova L, Skinner KM, Reeve JN.	J Bacteriol	10.1128/jb.00982-09	2009
Metabolism	Interactions between the archaeal Cdc6 and MCM proteins modulate their biochemical properties.	Kasiviswanathan R, Shin JH, Kelman Z.	Nucleic Acids Res	10.1093/nar/gki807	2005
	Molecular signature of hypersaline adaptation: insights from genome and proteome composition of halophilic prokaryotes.	Paul S, Bag SK, Das S, Harvill ET, Dutta C.	Genome Biol	10.1186/gb-2008-9-4-r70	2008
Metabolism	Role of the fused corrinoid/methyl transfer protein CmtA during CO-dependent growth of Methanosarcina acetivorans.	Vepachedu VR, Ferry JG.	J Bacteriol	10.1128/jb.00593-12	2012
Enzymology	The oligomeric architecture of the archaeal exosome is important for processive and efficient RNA degradation.	Audin MJ, Wurm JP, Cvetkovic MA, Sprangers R.	Nucleic Acids Res	10.1093/nar/gkw062	2016
Lipids	Heat Stress Dictates Microbial Lipid Composition along a Thermal Gradient in Marine Sediments.	Sollich M, Yoshinaga MY, Hausler S, Price RE, Hinrichs KU, Buhring SI.	Front Microbiol	10.3389/fmicb.2017.01550	2017
Metabolism	Substrate-induced change in the quaternary structure of type 2 isopentenyl diphosphate isomerase from Sulfolobus shibatae.	Nakatani H, Goda S, Unno H, Nagai T, Yoshimura T, Hemmi H.	J Bacteriol	10.1128/jb.00068-12	2012
Enzymology	MTH1745, a protein disulfide isomerase-like protein from thermophilic archaea, Methanothermobacter thermoautotrophicum involving in stress response.	Ding X, Lv ZM, Zhao Y, Min H, Yang WJ.	Cell Stress Chaperones	10.1007/s12192-008-0026-4	2008
Metabolism	Synthesis of Glu-tRNA(Gln) by engineered and natural aminoacyl-tRNA synthetases.	Rodriguez-Hernandez A, Bhaskaran H, Hadd A, Perona JJ.	Biochemistry	10.1021/bi100886z	2010
Enzymology	Critical domain interactions for type A RNase P RNA catalysis with and without the specificity domain.	Mao G, Srivastava AS, Wu S, Kosek D, Lindell M, Kirsebom LA.	PLoS One	10.1371/journal.pone.0192873	2018
	Comparative classification of species and the study of pathway evolution based on the alignment of metabolic pathways.	Mano A, Tuller T, Beja O, Pinter RY.	BMC Bioinformatics	10.1186/1471-2105-11-s1-s38	2010
Metabolism	Diversity of glycosyl hydrolases from cellulose-depleting communities enriched from casts of two earthworm species.	Beloqui A, Nechitaylo TY, Lopez-Cortes N, Ghazi A, Guazzaroni ME, Polaina J, Strittmatter AW, Reva O, Waliczek A, Yakimov MM, Golyshina OV, Ferrer M, Golyshin PN.	Appl Environ Microbiol	10.1128/aem.00902-10	2010
Genetics	Extensive Inter-Domain Lateral Gene Transfer in the Evolution of the Human Commensal Methanosphaera stadtmanae.	Lurie-Weinberger MN, Peeri M, Tuller T, Gophna U.	Front Genet	10.3389/fgene.2012.00182	2012
	Catalysis in Enzymatic Decarboxylations: Comparison of Selected Cofactor-dependent and Cofactor-independent Examples.	Jordan F, Patel H.	ACS Catal	10.1021/cs400272x	2013
Metabolism	Biochemical characterization of a dihydromethanopterin reductase involved in tetrahydromethanopterin biosynthesis in Methylobacterium extorquens AM1.	Caccamo MA, Malone CS, Rasche ME.	J Bacteriol	10.1128/jb.186.7.2068-2073.2004	2004
Phylogeny	Diversity of Metabolically Active Bacteria in Water-Flooded High-Temperature Heavy Oil Reservoir.	Nazina TN, Shestakova NM, Semenova EM, Korshunova AV, Kostrukova NK, Tourova TP, Min L, Feng Q, Poltaraus AB.	Front Microbiol	10.3389/fmicb.2017.00707	2017
	Functional responses of methanogenic archaea to syntrophic growth.	Walker CB, Redding-Johanson AM, Baidoo EE, Rajeev L, He Z, Hendrickson EL, Joachimiak MP, Stolyar S, Arkin AP, Leigh JA, Zhou J, Keasling JD, Mukhopadhyay A, Stahl DA.	ISME J	10.1038/ismej.2012.60	2012
Metabolism	Functionally distinct genes regulated by hydrogen limitation and growth rate in methanogenic Archaea.	Hendrickson EL, Haydock AK, Moore BC, Whitman WB, Leigh JA.	Proc Natl Acad Sci U S A	10.1073/pnas.0701157104	2007
Enzymology	Structure and Evolution of the Archaeal Lipid Synthesis Enzyme sn-Glycerol-1-phosphate Dehydrogenase.	Carbone V, Schofield LR, Zhang Y, Sang C, Dey D, Hannus IM, Martin WF, Sutherland-Smith AJ, Ronimus RS.	J Biol Chem	10.1074/jbc.m115.647461	2015
Metabolism	Gln-tRNAGln synthesis in a dynamic transamidosome from Helicobacter pylori, where GluRS2 hydrolyzes excess Glu-tRNAGln.	Huot JL, Fischer F, Corbeil J, Madore E, Lorber B, Diss G, Hendrickson TL, Kern D, Lapointe J.	Nucleic Acids Res	10.1093/nar/gkr619	2011
Genetics	aCPSF1 cooperates with terminator U-tract to dictate archaeal transcription termination efficacy.	Li J, Yue L, Li Z, Zhang W, Zhang B, Zhao F, Dong X.	Elife	10.7554/elife.70464	2021
Metabolism	Amino acid precursor supply in the biosynthesis of the RNA polymerase inhibitor streptolydigin by Streptomyces lydicus.	Gomez C, Horna DH, Olano C, Palomino-Schatzlein M, Pineda-Lucena A, Carbajo RJ, Brana AF, Mendez C, Salas JA.	J Bacteriol	10.1128/jb.05062-11	2011
Metabolism	Sense and sensibility: flagellum-mediated gene regulation.	Anderson JK, Smith TG, Hoover TR.	Trends Microbiol	10.1016/j.tim.2009.11.001	2010
Genetics	Dispensability of zinc and the putative zinc-binding domain in bacterial glutamyl-tRNA synthetase.	Chongdar N, Dasgupta S, Datta AB, Basu G.	Biosci Rep	10.1042/bsr20150005	2015
Phylogeny	Archaeal beta-CASP ribonucleases of the aCPSF1 family are orthologs of the eukaryal CPSF-73 factor.	Phung DK, Rinaldi D, Langendijk-Genevaux PS, Quentin Y, Carpousis AJ, Clouet-d'Orval B.	Nucleic Acids Res	10.1093/nar/gks1237	2013
Metabolism	Biosynthesis of phosphoserine in the Methanococcales.	Helgadottir S, Rosas-Sandoval G, Soll D, Graham DE.	J Bacteriol	10.1128/jb.01269-06	2007
Metabolism	Identification of methyl coenzyme M reductase A (mcrA) genes associated with methane-oxidizing archaea.	Hallam SJ, Girguis PR, Preston CM, Richardson PM, DeLong EF.	Appl Environ Microbiol	10.1128/aem.69.9.5483-5491.2003	2003
Genetics	A conserved MCM single-stranded DNA binding element is essential for replication initiation.	Froelich CA, Kang S, Epling LB, Bell SP, Enemark EJ.	Elife	10.7554/elife.01993	2014
Metabolism	Human HEL308 localizes to damaged replication forks and unwinds lagging strand structures.	Tafel AA, Wu L, McHugh PJ.	J Biol Chem	10.1074/jbc.m111.228189	2011
Metabolism	Discovery and characterization of an amidinotransferase involved in the modification of archaeal tRNA.	Phillips G, Chikwana VM, Maxwell A, El-Yacoubi B, Swairjo MA, Iwata-Reuyl D, de Crecy-Lagard V.	J Biol Chem	10.1074/jbc.m110.102236	2010
	Application of a Colorimetric Assay to Identify Putative Ribofuranosylaminobenzene 5'-Phosphate Synthase Genes Expressed with Activity in Escherichia coli.	Bechard ME, Chhatwal S, Garcia RE, Rasche ME.	Biol Proced Online	10.1251/bpo48	2003
Phylogeny	Annotation and Classification of CRISPR-Cas Systems.	Makarova KS, Koonin EV.	Methods Mol Biol	10.1007/978-1-4939-2687-9_4	2015
Metabolism	Mycobacterium smegmatis SftH exemplifies a distinctive clade of superfamily II DNA-dependent ATPases with 3' to 5' translocase and helicase activities.	Yakovleva L, Shuman S.	Nucleic Acids Res	10.1093/nar/gks417	2012
Metabolism	Thermoplasma acidophilum Cdc6 protein stimulates MCM helicase activity by regulating its ATPase activity.	Haugland GT, Sakakibara N, Pey AL, Rollor CR, Birkeland NK, Kelman Z.	Nucleic Acids Res	10.1093/nar/gkn548	2008
Enzymology	Structure of an archaeal-type phosphoenolpyruvate carboxylase sensitive to inhibition by aspartate.	Dharmarajan L, Kraszewski JL, Mukhopadhyay B, Dunten PW.	Proteins	10.1002/prot.23006	2011
Metabolism	An uncharacterized member of the ribokinase family in Thermococcus kodakarensis exhibits myo-inositol kinase activity.	Sato T, Fujihashi M, Miyamoto Y, Kuwata K, Kusaka E, Fujita H, Miki K, Atomi H.	J Biol Chem	10.1074/jbc.m113.457259	2013
	TFB1 or TFB2 is sufficient for Thermococcus kodakaraensis viability and for basal transcription in vitro.	Santangelo TJ, Cubonova L, James CL, Reeve JN.	J Mol Biol	10.1016/j.jmb.2006.12.069	2007
Metabolism	Structural and Mechanistic Insights into the Pseudomonas fluorescens 2-Nitrobenzoate 2-Nitroreductase NbaA.	Kim YH, Song W, Kim JS, Jiao L, Lee K, Ha NC.	Appl Environ Microbiol	10.1128/aem.01289-15	2015
Metabolism	Investigations into microsporidian methionine aminopeptidase type 2: a therapeutic target for microsporidiosis.	Zhang H, Huang H, Cali A, Takvorian PM, Feng X, Zhou G, Weiss LM.	Folia Parasitol (Praha)	10.14411/fp.2005.023	2005
Metabolism	Farnesyl diphosphate synthase: the art of compromise between substrate selectivity and stereoselectivity.	Thulasiram HV, Poulter CD.	J Am Chem Soc	10.1021/ja065573b	2006
	Studies on the mechanism of inhibition of bacterial ribonuclease P by aminoglycoside derivatives.	Kawamoto SA, Sudhahar CG, Hatfield CL, Sun J, Behrman EJ, Gopalan V.	Nucleic Acids Res	10.1093/nar/gkm1088	2008
	A novel mechanism for regulating the activity of proliferating cell nuclear antigen by a small protein.	Li Z, Huang RY, Yopp DC, Hileman TH, Santangelo TJ, Hurwitz J, Hudgens JW, Kelman Z.	Nucleic Acids Res	10.1093/nar/gku239	2014
	The appearance of pyrrolysine in tRNAHis guanylyltransferase by neutral evolution.	Heinemann IU, O'Donoghue P, Madinger C, Benner J, Randau L, Noren CJ, Soll D.	Proc Natl Acad Sci U S A	10.1073/pnas.0912072106	2009
	Physiological differentiation within a single-species biofilm fueled by serpentinization.	Brazelton WJ, Mehta MP, Kelley DS, Baross JA.	mBio	10.1128/mbio.00127-11	2011
	Crystal structure of a two-subunit TrkA octameric gating ring assembly.	Deller MC, Johnson HA, Miller MD, Spraggon G, Elsliger MA, Wilson IA, Lesley SA.	PLoS One	10.1371/journal.pone.0122512	2015
Genetics	The haloarchaeal MCM proteins: bioinformatic analysis and targeted mutagenesis of the beta7-beta8 and beta9-beta10 hairpin loops and conserved zinc binding domain cysteines.	Kristensen TP, Maria Cherian R, Gray FC, MacNeill SA.	Front Microbiol	10.3389/fmicb.2014.00123	2014
	How difficult is it to fold a knotted protein? In silico insights from surface-tethered folding experiments.	Soler MA, Faisca PF.	PLoS One	10.1371/journal.pone.0052343	2012
Metabolism	Two-step aminoacylation of tRNA without channeling in Archaea.	Bhaskaran H, Perona JJ.	J Mol Biol	10.1016/j.jmb.2011.06.039	2011
Metabolism	Glutathione synthetase homologs encode alpha-L-glutamate ligases for methanogenic coenzyme F420 and tetrahydrosarcinapterin biosyntheses.	Li H, Xu H, Graham DE, White RH.	Proc Natl Acad Sci U S A	10.1073/pnas.1733391100	2003
Phylogeny	Comprehensive computational analysis of Hmd enzymes and paralogs in methanogenic Archaea.	Goldman AD, Leigh JA, Samudrala R.	BMC Evol Biol	10.1186/1471-2148-9-199	2009
Genetics	Analysis of the crystal structure of an active MCM hexamer.	Miller JM, Arachea BT, Epling LB, Enemark EJ.	Elife	10.7554/elife.03433	2014
	LVIS553 transcriptional regulator specifically recognizes novobiocin as an effector molecule.	Pagliai FA, Gardner CL, Pande SG, Lorca GL.	J Biol Chem	10.1074/jbc.m110.111138	2010
Metabolism	Stimulation of MCM helicase activity by a Cdc6 protein in the archaeon Thermoplasma acidophilum.	Haugland GT, Shin JH, Birkeland NK, Kelman Z.	Nucleic Acids Res	10.1093/nar/gkl864	2006
Metabolism	Correlation of methane production and functional gene transcriptional activity in a peat soil.	Freitag TE, Prosser JI.	Appl Environ Microbiol	10.1128/aem.01021-09	2009
	Archaeal Tuc1/Ncs6 homolog required for wobble uridine tRNA thiolation is associated with ubiquitin-proteasome, translation, and RNA processing system homologs.	Chavarria NE, Hwang S, Cao S, Fu X, Holman M, Elbanna D, Rodriguez S, Arrington D, Englert M, Uthandi S, Soll D, Maupin-Furlow JA.	PLoS One	10.1371/journal.pone.0099104	2014
Metabolism	A unique combination of genetic systems for the synthesis of trehalose in Rubrobacter xylanophilus: properties of a rare actinobacterial TreT.	Nobre A, Alarico S, Fernandes C, Empadinhas N, da Costa MS.	J Bacteriol	10.1128/jb.01055-08	2008
	Methanogens: biochemical background and biotechnological applications.	Enzmann F, Mayer F, Rother M, Holtmann D.	AMB Express	10.1186/s13568-017-0531-x	2018
Genetics	CRISPR loci reveal networks of gene exchange in archaea.	Brodt A, Lurie-Weinberger MN, Gophna U.	Biol Direct	10.1186/1745-6150-6-65	2011
Proteome	Conserved eukaryotic histone-fold residues substituted into an archaeal histone increase DNA affinity but reduce complex flexibility.	Soares DJ, Marc F, Reeve JN.	J Bacteriol	10.1128/jb.185.11.3453-3457.2003	2003
Metabolism	The electron transfer system of syntrophically grown Desulfovibrio vulgaris.	Walker CB, He Z, Yang ZK, Ringbauer JA, He Q, Zhou J, Voordouw G, Wall JD, Arkin AP, Hazen TC, Stolyar S, Stahl DA.	J Bacteriol	10.1128/jb.00356-09	2009
Metabolism	Catalysis by orotidine 5'-monophosphate decarboxylase: effect of 5-fluoro and 4'-substituents on the decarboxylation of two-part substrates.	Goryanova B, Spong K, Amyes TL, Richard JP.	Biochemistry	10.1021/bi301650d	2013
	Many nonuniversal archaeal ribosomal proteins are found in conserved gene clusters.	Wang J, Dasgupta I, Fox GE.	Archaea	10.1155/2009/971494	2009
Metabolism	Genomewide and biochemical analyses of DNA-binding activity of Cdc6/Orc1 and Mcm proteins in Pyrococcus sp.	Matsunaga F, Glatigny A, Mucchielli-Giorgi MH, Agier N, Delacroix H, Marisa L, Durosay P, Ishino Y, Aggerbeck L, Forterre P.	Nucleic Acids Res	10.1093/nar/gkm212	2007
Metabolism	Polyphasic analyses of methanogenic archaeal communities in agricultural biogas plants.	Nettmann E, Bergmann I, Pramschufer S, Mundt K, Plogsties V, Herrmann C, Klocke M.	Appl Environ Microbiol	10.1128/aem.01423-09	2010
	In silico screening of archaeal tRNA-encoding genes having multiple introns with bulge-helix-bulge splicing motifs.	Sugahara J, Yachie N, Arakawa K, Tomita M.	RNA	10.1261/rna.309507	2007
	Revisiting the operational RNA code for amino acids: Ensemble attributes and their implications.	Shaul S, Berel D, Benjamini Y, Graur D.	RNA	10.1261/rna.1745910	2010
Metabolism	The U3 small nucleolar ribonucleoprotein component Imp4p is a telomeric DNA-binding protein.	Hsieh YC, Tu PJ, Lee YY, Kuo CC, Lin YC, Wu CF, Lin JJ.	Biochem J	10.1042/bj20070968	2007
	An anaerobic-type alpha-ketoglutarate ferredoxin oxidoreductase completes the oxidative tricarboxylic acid cycle of Mycobacterium tuberculosis.	Baughn AD, Garforth SJ, Vilcheze C, Jacobs WR.	PLoS Pathog	10.1371/journal.ppat.1000662	2009
	Social evolution in multispecies biofilms.	Mitri S, Xavier JB, Foster KR.	Proc Natl Acad Sci U S A	10.1073/pnas.1100292108	2011
Metabolism	Solution structure of an archaeal RNase P binary protein complex: formation of the 30-kDa complex between Pyrococcus furiosus RPP21 and RPP29 is accompanied by coupled protein folding and highlights critical features for protein-protein and protein-RNA interactions.	Xu Y, Amero CD, Pulukkunat DK, Gopalan V, Foster MP.	J Mol Biol	10.1016/j.jmb.2009.08.068	2009
Phylogeny	Comparative molecular analysis of chemolithoautotrophic bacterial diversity and community structure from coastal saline soils, Gujarat, India.	Yousuf B, Sanadhya P, Keshri J, Jha B.	BMC Microbiol	10.1186/1471-2180-12-150	2012
	Crystal structure of a novel Sm-like protein of putative cyanophage origin at 2.60 A resolution.	Das D, Kozbial P, Axelrod HL, Miller MD, McMullan D, Krishna SS, Abdubek P, Acosta C, Astakhova T, Burra P, Carlton D, Chen C, Chiu HJ, Clayton T, Deller MC, Duan L, Elias Y, Elsliger MA, Ernst D, Farr C, Feuerhelm J, Grzechnik A, Grzechnik SK, Hale J, Han GW, Jaroszewski L, Jin KK, Johnson HA, Klock HE, Knuth MW, Kumar A, Marciano D, Morse AT, Murphy KD, Nigoghossian E, Nopakun A, Okach L, Oommachen S, Paulsen J, Puckett C, Reyes R, Rife CL, Sefcovic N, Sudek S, Tien H, Trame C, Trout CV, van den Bedem H, Weekes D, White A, Xu Q, Hodgson KO, Wooley J, Deacon AM, Godzik A, Lesley SA, Wilson IA.	Proteins	10.1002/prot.22360	2009
Enzymology	Idiosyncratic helix-turn-helix motif in Methanosarcina barkeri seryl-tRNA synthetase has a critical architectural role.	Bilokapic S, Ivic N, Godinic-Mikulcic V, Piantanida I, Ban N, Weygand-Durasevic I.	J Biol Chem	10.1074/jbc.m808501200	2009
Metabolism	Kinetics of tRNA folding monitored by aminoacylation.	Bhaskaran H, Rodriguez-Hernandez A, Perona JJ.	RNA	10.1261/rna.030080.111	2012
Enzymology	Atomic structures and functional implications of the archaeal RecQ-like helicase Hjm.	Oyama T, Oka H, Mayanagi K, Shirai T, Matoba K, Fujikane R, Ishino Y, Morikawa K.	BMC Struct Biol	10.1186/1472-6807-9-2	2009
	On the evolution of the tRNA-dependent amidotransferases, GatCAB and GatDE.	Sheppard K, Soll D.	J Mol Biol	10.1016/j.jmb.2008.01.016	2008
	The catalytic domains of thiamine triphosphatase and CyaB-like adenylyl cyclase define a novel superfamily of domains that bind organic phosphates.	Iyer LM, Aravind L.	BMC Genomics	10.1186/1471-2164-3-33	2002
Metabolism	Tail-anchor targeting by a Get3 tetramer: the structure of an archaeal homologue.	Suloway CJ, Rome ME, Clemons WM.	EMBO J	10.1038/emboj.2011.433	2012
	The uvrA, uvrB and uvrC genes are required for repair of ultraviolet light induced DNA photoproducts in Halobacterium sp. NRC-1.	Crowley DJ, Boubriak I, Berquist BR, Clark M, Richard E, Sullivan L, DasSarma S, McCready S.	Saline Syst	10.1186/1746-1448-2-11	2006
Metabolism	The hyperthermophilic euryarchaeon Archaeoglobus fulgidus repairs uracil by single-nucleotide replacement.	Knaevelsrud I, Moen MN, Grosvik K, Haugland GT, Birkeland NK, Klungland A, Leiros I, Bjelland S.	J Bacteriol	10.1128/jb.00135-10	2010
Genetics	An extended network of genomic maintenance in the archaeon Pyrococcus abyssi highlights unexpected associations between eucaryotic homologs.	Pluchon PF, Fouqueau T, Creze C, Laurent S, Briffotaux J, Hogrel G, Palud A, Henneke G, Godfroy A, Hausner W, Thomm M, Nicolas J, Flament D.	PLoS One	10.1371/journal.pone.0079707	2013
Metabolism	Something old, something new, something borrowed; how the thermoacidophilic archaeon Sulfolobus solfataricus responds to oxidative stress.	Maaty WS, Wiedenheft B, Tarlykov P, Schaff N, Heinemann J, Robison-Cox J, Valenzuela J, Dougherty A, Blum P, Lawrence CM, Douglas T, Young MJ, Bothner B.	PLoS One	10.1371/journal.pone.0006964	2009
Metabolism	Lysine-2,3-aminomutase and beta-lysine acetyltransferase genes of methanogenic archaea are salt induced and are essential for the biosynthesis of Nepsilon-acetyl-beta-lysine and growth at high salinity.	Pfluger K, Baumann S, Gottschalk G, Lin W, Santos H, Muller V.	Appl Environ Microbiol	10.1128/aem.69.10.6047-6055.2003	2003
Metabolism	Alternative mechanisms for coordinating polymerase alpha and MCM helicase.	Lee C, Liachko I, Bouten R, Kelman Z, Tye BK.	Mol Cell Biol	10.1128/mcb.01240-09	2010
Metabolism	Concerted loading of Mcm2-7 double hexamers around DNA during DNA replication origin licensing.	Remus D, Beuron F, Tolun G, Griffith JD, Morris EP, Diffley JF.	Cell	10.1016/j.cell.2009.10.015	2009
	The Dark Side of the Mushroom Spring Microbial Mat: Life in the Shadow of Chlorophototrophs. I. Microbial Diversity Based on 16S rRNA Gene Amplicons and Metagenomic Sequencing.	Thiel V, Wood JM, Olsen MT, Tank M, Klatt CG, Ward DM, Bryant DA.	Front Microbiol	10.3389/fmicb.2016.00919	2016
Metabolism	snRNA 3' end formation requires heterodimeric association of integrator subunits.	Albrecht TR, Wagner EJ.	Mol Cell Biol	10.1128/mcb.06511-11	2012
Metabolism	The genome of the Gram-positive metal- and sulfate-reducing bacterium Desulfotomaculum reducens strain MI-1.	Junier P, Junier T, Podell S, Sims DR, Detter JC, Lykidis A, Han CS, Wigginton NS, Gaasterland T, Bernier-Latmani R.	Environ Microbiol	10.1111/j.1462-2920.2010.02242.x	2010
Enzymology	Kinetic and spectroscopic characterization of type II isopentenyl diphosphate isomerase from Thermus thermophilus: evidence for formation of substrate-induced flavin species.	Rothman SC, Helm TR, Poulter CD.	Biochemistry	10.1021/bi0616347	2007
Phylogeny	BranchClust: a phylogenetic algorithm for selecting gene families.	Poptsova MS, Gogarten JP.	BMC Bioinformatics	10.1186/1471-2105-8-120	2007
Metabolism	Identification of essential and non-essential single-stranded DNA-binding proteins in a model archaeal organism.	Skowyra A, MacNeill SA.	Nucleic Acids Res	10.1093/nar/gkr838	2012
Metabolism	A genomic timescale of prokaryote evolution: insights into the origin of methanogenesis, phototrophy, and the colonization of land.	Battistuzzi FU, Feijao A, Hedges SB.	BMC Evol Biol	10.1186/1471-2148-4-44	2004
Metabolism	Transfer RNA-dependent amino acid biosynthesis: an essential route to asparagine formation.	Min B, Pelaschier JT, Graham DE, Tumbula-Hansen D, Soll D.	Proc Natl Acad Sci U S A	10.1073/pnas.012027399	2002
Enzymology	Post-transfer editing in vitro and in vivo by the beta subunit of phenylalanyl-tRNA synthetase.	Roy H, Ling J, Irnov M, Ibba M.	EMBO J	10.1038/sj.emboj.7600474	2004
Metabolism	Proton transfer from C-6 of uridine 5'-monophosphate catalyzed by orotidine 5'-monophosphate decarboxylase: formation and stability of a vinyl carbanion intermediate and the effect of a 5-fluoro substituent.	Tsang WY, Wood BM, Wong FM, Wu W, Gerlt JA, Amyes TL, Richard JP.	J Am Chem Soc	10.1021/ja3058474	2012
	Different patterns of evolution for duplicated DNA repair genes in bacteria of the Xanthomonadales group.	Martins-Pinheiro M, Galhardo RS, Lage C, Lima-Bessa KM, Aires KA, Menck CF.	BMC Evol Biol	10.1186/1471-2148-4-29	2004
	Genome scale prediction of substrate specificity for acyl adenylate superfamily of enzymes based on active site residue profiles.	Khurana P, Gokhale RS, Mohanty D.	BMC Bioinformatics	10.1186/1471-2105-11-57	2010
	Identification of SmtB/ArsR cis elements and proteins in archaea using the Prokaryotic InterGenic Exploration Database (PIGED).	Bose M, Slick D, Sarto MJ, Murphy P, Roberts D, Roberts J, Barber RD.	Archaea	10.1155/2006/837139	2006
Enzymology	A cambialistic superoxide dismutase in the thermophilic photosynthetic bacterium Chloroflexus aurantiacus.	Lancaster VL, LoBrutto R, Selvaraj FM, Blankenship RE.	J Bacteriol	10.1128/jb.186.11.3408-3414.2004	2004
Metabolism	Redundant synthesis of cysteinyl-tRNACys in Methanosarcina mazei.	Hauenstein SI, Perona JJ.	J Biol Chem	10.1074/jbc.m801839200	2008
Metabolism	From one amino acid to another: tRNA-dependent amino acid biosynthesis.	Sheppard K, Yuan J, Hohn MJ, Jester B, Devine KM, Soll D.	Nucleic Acids Res	10.1093/nar/gkn015	2008
Metabolism	Flavin mononucleotide-binding flavoprotein family in the domain Archaea.	Ding YH, Ferry JG.	J Bacteriol	10.1128/jb.186.1.90-97.2004	2004
	A comprehensive history of motility and Archaellation in Archaea.	Jarrell KF, Albers SV, Machado JNS.	FEMS Microbes	10.1093/femsmc/xtab002	2021
	Searching for RNA genes using base-composition statistics.	Schattner P.	Nucleic Acids Res	10.1093/nar/30.9.2076	2002
Enzymology	Insights into tRNA-dependent amidotransferase evolution and catalysis from the structure of the Aquifex aeolicus enzyme.	Wu J, Bu W, Sheppard K, Kitabatake M, Kwon ST, Soll D, Smith JL.	J Mol Biol	10.1016/j.jmb.2009.06.014	2009
	A CCCH zinc finger conserved in a replication protein a homolog found in diverse Euryarchaeotes.	Lin Y, Robbins JB, Nyannor EK, Chen YH, Cann IK.	J Bacteriol	10.1128/jb.187.23.7881-7889.2005	2005
Metabolism	Identification and isolation of the polyferredoxin from Methanobacterium thermoautotrophicum strain delta H.	Steigerwald VJ, Pihl TD, Reeve JN.	Proc Natl Acad Sci U S A	10.1073/pnas.89.15.6929	1992
Metabolism	Different catalytic mechanisms in mammalian selenocysteine- and cysteine-containing methionine-R-sulfoxide reductases.	Kim HY, Gladyshev VN.	PLoS Biol	10.1371/journal.pbio.0030375	2005
Metabolism	Topology of AspT, the aspartate:alanine antiporter of Tetragenococcus halophilus, determined by site-directed fluorescence labeling.	Nanatani K, Fujiki T, Kanou K, Takeda-Shitaka M, Umeyama H, Ye L, Wang X, Nakajima T, Uchida T, Maloney PC, Abe K.	J Bacteriol	10.1128/jb.00088-07	2007
	Flavin-Based Electron Bifurcation, Ferredoxin, Flavodoxin, and Anaerobic Respiration With Protons (Ech) or NAD⁺ (Rnf) as Electron Acceptors: A Historical Review.	Buckel W, Thauer RK.	Front Microbiol	10.3389/fmicb.2018.00401	2018
Genetics	An archaeal chromosomal autonomously replicating sequence element from an extreme halophile, Halobacterium sp. strain NRC-1.	Berquist BR, DasSarma S.	J Bacteriol	10.1128/jb.185.20.5959-5966.2003	2003
Metabolism	Biochemical characterization of Cdc6/Orc1 binding to the replication origin of the euryarchaeon Methanothermobacter thermoautotrophicus.	Capaldi SA, Berger JM.	Nucleic Acids Res	10.1093/nar/gkh819	2004
Genetics	Genomic context analysis in Archaea suggests previously unrecognized links between DNA replication and translation.	Berthon J, Cortez D, Forterre P.	Genome Biol	10.1186/gb-2008-9-4-r71	2008
Enzymology	Biochemical properties and base excision repair complex formation of apurinic/apyrimidinic endonuclease from Pyrococcus furiosus.	Kiyonari S, Tahara S, Shirai T, Iwai S, Ishino S, Ishino Y.	Nucleic Acids Res	10.1093/nar/gkp720	2009
Metabolism	Crystal structure and function of 5-formaminoimidazole-4-carboxamide ribonucleotide synthetase from Methanocaldococcus jannaschii.	Zhang Y, White RH, Ealick SE.	Biochemistry	10.1021/bi701406g	2008
	Close Interspecies Interactions between Prokaryotes from Sulfureous Environments.	Muller J, Overmann J.	Front Microbiol	10.3389/fmicb.2011.00146	2011
Metabolism	Uracil-DNA glycosylase of Thermoplasma acidophilum directs long-patch base excision repair, which is promoted by deoxynucleoside triphosphates and ATP/ADP, into short-patch repair.	Moen MN, Knaevelsrud I, Haugland GT, Grosvik K, Birkeland NK, Klungland A, Bjelland S.	J Bacteriol	10.1128/jb.00233-11	2011
	Archaeal type IV pili and their involvement in biofilm formation.	Pohlschroder M, Esquivel RN.	Front Microbiol	10.3389/fmicb.2015.00190	2015
Metabolism	Archaeal Hel308 helicase targets replication forks in vivo and in vitro and unwinds lagging strands.	Guy CP, Bolt EL.	Nucleic Acids Res	10.1093/nar/gki685	2005
Enzymology	Glycerate kinase of the hyperthermophilic archaeon Thermoproteus tenax: new insights into the phylogenetic distribution and physiological role of members of the three different glycerate kinase classes.	Kehrer D, Ahmed H, Brinkmann H, Siebers B.	BMC Genomics	10.1186/1471-2164-8-301	2007
	HMt, a histone-related protein from Methanobacterium thermoautotrophicum delta H.	Tabassum R, Sandman KM, Reeve JN.	J Bacteriol	10.1128/jb.174.24.7890-7895.1992	1992
	Molecular mechanisms of CRISPR-mediated microbial immunity.	Gasiunas G, Sinkunas T, Siksnys V.	Cell Mol Life Sci	10.1007/s00018-013-1438-6	2014
	Dissecting the antigenic mosaic of the Archaebacterium Methanobacterium thermoautotrophicum by monoclonal antibodies of defined molecular specificity.	Conway de Macario E, Macario AJ, Magarinos MC, Konig H, Kandler O.	Proc Natl Acad Sci U S A	10.1073/pnas.80.20.6346	1983
Phylogeny	Phylogenomic analysis of the GIY-YIG nuclease superfamily.	Dunin-Horkawicz S, Feder M, Bujnicki JM.	BMC Genomics	10.1186/1471-2164-7-98	2006
Phylogeny	Horizontal gene transfer in chromalveolates.	Nosenko T, Bhattacharya D.	BMC Evol Biol	10.1186/1471-2148-7-173	2007
	Development of a markerless genetic exchange method for Methanosarcina acetivorans C2A and its use in construction of new genetic tools for methanogenic archaea.	Pritchett MA, Zhang JK, Metcalf WW.	Appl Environ Microbiol	10.1128/aem.70.3.1425-1433.2004	2004
	SIGI: score-based identification of genomic islands.	Merkl R.	BMC Bioinformatics	10.1186/1471-2105-5-22	2004
Enzymology	Modelling the evolution of the archeal tryptophan synthase.	Merkl R.	BMC Evol Biol	10.1186/1471-2148-7-59	2007
Genetics	Genome sequence and global gene expression of Q54, a new phage species linking the 936 and c2 phage species of Lactococcus lactis.	Fortier LC, Bransi A, Moineau S.	J Bacteriol	10.1128/jb.00581-06	2006
	Detection of novel members, structure-function analysis and evolutionary classification of the 2H phosphoesterase superfamily.	Mazumder R, Iyer LM, Vasudevan S, Aravind L.	Nucleic Acids Res	10.1093/nar/gkf645	2002
Phylogeny	Domain-based small molecule binding site annotation.	Snyder KA, Feldman HJ, Dumontier M, Salama JJ, Hogue CW.	BMC Bioinformatics	10.1186/1471-2105-7-152	2006
Metabolism	Evolutionary primacy of sodium bioenergetics.	Mulkidjanian AY, Galperin MY, Makarova KS, Wolf YI, Koonin EV.	Biol Direct	10.1186/1745-6150-3-13	2008
Enzymology	Component A3 of the methylcoenzyme M methylreductase system of Methanobacterium thermoautotrophicum delta H: resolution into two components.	Rouviere PE, Wolfe RS.	J Bacteriol	10.1128/jb.171.9.4556-4562.1989	1989
	Component A2 of methylcoenzyme M reductase system from Methanobacterium thermoautotrophicum delta H: nucleotide sequence and functional expression by Escherichia coli.	Kuhner CH, Lindenbach BD, Wolfe RS.	J Bacteriol	10.1128/jb.175.10.3195-3203.1993	1993
	Tec3, a new developmentally eliminated DNA element in Euplotes crassus.	Jacobs ME, Sanchez-Blanco A, Katz LA, Klobutcher LA.	Eukaryot Cell	10.1128/ec.2.1.103-114.2003	2003
	Vitamin contents of archaebacteria.	Noll KM, Barber TS.	J Bacteriol	10.1128/jb.170.9.4315-4321.1988	1988
	One ancestor for two codes viewed from the perspective of two complementary modes of tRNA aminoacylation.	Rodin AS, Szathmary E, Rodin SN.	Biol Direct	10.1186/1745-6150-4-4	2009
	Natural history of S-adenosylmethionine-binding proteins.	Kozbial PZ, Mushegian AR.	BMC Struct Biol	10.1186/1472-6807-5-19	2005
	Archaeal extrachromosomal genetic elements.	Wang H, Peng N, Shah SA, Huang L, She Q.	Microbiol Mol Biol Rev	10.1128/mmbr.00042-14	2015
Metabolism	A Shuttle-Vector System Allows Heterologous Gene Expression in the Thermophilic Methanogen Methanothermobacter thermautotrophicus DeltaH.	Fink C, Beblawy S, Enkerlin AM, Muhling L, Angenent LT, Molitor B	mBio	10.1128/mBio.02766-21	2021
Phylogeny	Comparative genomic analysis reveals starvation survival systems in Methanothermobacter thermautotrophicus DeltaH.	Prathiviraj R, Chellapandi P	Anaerobe	10.1016/j.anaerobe.2020.102216	2020
Metabolism	Functional annotation of operome from Methanothermobacter thermautotrophicus DeltaH: An insight to metabolic gap filling.	Prathiviraj R, Chellapandi P	Int J Biol Macromol	10.1016/j.ijbiomac.2018.11.100	2018
Genetics	Intergenomic evolution and metabolic cross-talk between rumen and thermophilic autotrophic methanogenic archaea.	Bharathi M, Chellapandi P	Mol Phylogenet Evol	10.1016/j.ympev.2016.11.008	2016
	Methanothermobacter thermautotrophicus modulates its membrane lipids in response to hydrogen and nutrient availability.	Yoshinaga MY, Gagen EJ, Wormer L, Broda NK, Meador TB, Wendt J, Thomm M, Hinrichs KU	Front Microbiol	10.3389/fmicb.2015.00005	2015
Metabolism	Physiological and genetic basis for self-aggregation of a thermophilic hydrogenotrophic methanogen, Methanothermobacter strain CaT2.	Kosaka T, Toh H, Fujiyama A, Sakaki Y, Watanabe K, Meng XY, Hanada S, Toyoda A	Environ Microbiol Rep	10.1111/1758-2229.12128	2013
Stress	Without salt, the 'thermophilic' protein Mth10b is just mesophilic.	Zhang N, Pan XM, Ge M	PLoS One	10.1371/journal.pone.0053125	2012
Metabolism	Acceleration of cellulose degradation and shift of product via methanogenic co-culture of a cellulolytic bacterium with a hydrogenotrophic methanogen.	Sasaki D, Morita M, Sasaki K, Watanabe A, Ohmura N	J Biosci Bioeng	10.1016/j.jbiosc.2012.05.002	2012
Metabolism	Molecular mechanism underlying the interaction of typical Sac10b family proteins with DNA.	Liu YF, Zhang N, Liu X, Wang X, Wang ZX, Chen Y, Yao HW, Ge M, Pan XM	PLoS One	10.1371/journal.pone.0034986	2012
Metabolism	Comparative proteomic analysis of Methanothermobacter themautotrophicus DeltaH in pure culture and in co-culture with a butyrate-oxidizing bacterium.	Enoki M, Shinzato N, Sato H, Nakamura K, Kamagata Y	PLoS One	10.1371/journal.pone.0024309	2011
Metabolism	Mth10b, a unique member of the Sac10b family, does not bind nucleic acid.	Liu YF, Zhang N, Yao HW, Pan XM, Ge M	PLoS One	10.1371/journal.pone.0019977	2011
Metabolism	Crystal structure analysis of DNA uridine endonuclease Mth212 bound to DNA.	Lakomek K, Dickmanns A, Ciirdaeva E, Schomacher L, Ficner R	J Mol Biol	10.1016/j.jmb.2010.04.044	2010
Metabolism	Archaeal DNA uracil repair via direct strand incision: A minimal system reconstituted from purified components.	Schomacher L, Schurer KA, Ciirdaeva E, McDermott P, Chong JP, Kramer W, Fritz HJ	DNA Repair (Amst)	10.1016/j.dnarep.2010.01.004	2010
Metabolism	An examination of the relationship between active site loop size and thermodynamic activation parameters for orotidine 5'-monophosphate decarboxylase from mesophilic and thermophilic organisms.	Toth K, Amyes TL, Wood BM, Chan KK, Gerlt JA, Richard JP	Biochemistry	10.1021/bi901064k	2009
Metabolism	DNA uracil repair initiated by the archaeal ExoIII homologue Mth212 via direct strand incision.	Schomacher L, Chong JP, McDermott P, Kramer W, Fritz HJ	Nucleic Acids Res	10.1093/nar/gkp102	2009
Metabolism	Functional characterization of the DnaK chaperone system from the archaeon Methanothermobacter thermautotrophicus DeltaH.	Popp SL, Reinstein J	FEBS Lett	10.1016/j.febslet.2008.12.062	2009
Enzymology	Specific DNA binding of a potential transcriptional regulator, inosine 5'-monophosphate dehydrogenase-related protein VII, to the promoter region of a methyl coenzyme m reductase I-encoding operon retrieved from Methanothermobacter thermautotrophicus strain DeltaH.	Shinzato N, Enoki M, Sato H, Nakamura K, Matsui T, Kamagata Y	Appl Environ Microbiol	10.1128/AEM.02155-07	2008
Metabolism	Comparative transcriptome analysis of responses of Methanothermobacter thermautotrophicus to different environmental stimuli.	Kato S, Kosaka T, Watanabe K	Environ Microbiol	10.1111/j.1462-2920.2007.01508.x	2007
	Biochemical analysis of neomycin-resistance in the methanoarchaeon Methanothermobacter thermautotrophicus and some implications for energetic processes in this strain.	Majernik A, Cubonova L, Polak P, Smigan P, Greksak M	Anaerobe	10.1016/S1075-9964(03)00042-8	2003
Cultivation	Methanogenesis is Ca2+ dependent in Methanothermobacter thermautotrophicus strain DeltaH.	Vancek M, Vidova M, Majernik AI, Smigan P	FEMS Microbiol Lett	10.1111/j.1574-6968.2006.00232.x	2006
Metabolism	Coaggregation facilitates interspecies hydrogen transfer between Pelotomaculum thermopropionicum and Methanothermobacter thermautotrophicus.	Ishii S, Kosaka T, Hori K, Hotta Y, Watanabe K	Appl Environ Microbiol	10.1128/AEM.71.12.7838-7845.2005	2005
Phylogeny	Improved strategy for presumptive identification of methanogens using 16S riboprinting.	Wright AD, Pimm C	J Microbiol Methods	10.1016/s0167-7012(03)00169-6	2003
Metabolism	The cobY gene of the archaeon Halobacterium sp. strain NRC-1 is required for de novo cobamide synthesis.	Woodson JD, Peck RF, Krebs MP, Escalante-Semerena JC	J Bacteriol	10.1128/JB.185.1.311-316.2003	2003
Metabolism	Differential expression of methanogenesis genes of Methanothermobacter thermoautotrophicus (formerly Methanobacterium thermoautotrophicum) in pure culture and in cocultures with fatty acid-oxidizing syntrophs.	Luo HW, Zhang H, Suzuki T, Hattori S, Kamagata Y	Appl Environ Microbiol	10.1128/AEM.68.3.1173-1179.2002	2002
Metabolism	The zinc finger domain of the archaeal minichromosome maintenance protein is required for helicase activity.	Poplawski A, Grabowski B, Long SE, Kelman Z	J Biol Chem	10.1074/jbc.M108519200	2001
Metabolism	Convenient fluorescence-based methods to measure membrane potential and intracellular pH in the Archaeon Methanobacterium thermoautotrophicum.	de Poorter LM, Keltjens JT	J Microbiol Methods	10.1016/s0167-7012(01)00312-8	2001
Metabolism	Crystal structure of the MJ0490 gene product of the hyperthermophilic archaebacterium Methanococcus jannaschii, a novel member of the lactate/malate family of dehydrogenases.	Lee BI, Chang C, Cho SJ, Eom SH, Kim KK, Yu YG, Suh SW	J Mol Biol	10.1006/jmbi.2001.4532	2001
Metabolism	A DNA ligase from a hyperthermophilic archaeon with unique cofactor specificity.	Nakatani M, Ezaki S, Atomi H, Imanaka T	J Bacteriol	10.1128/JB.182.22.6424-6433.2000	2000
Enzymology	Identification of an alternative nucleoside triphosphate: 5'-deoxyadenosylcobinamide phosphate nucleotidyltransferase in Methanobacterium thermoautotrophicum delta H.	Thomas MG, Escalante-Semerena JC	J Bacteriol	10.1128/JB.182.15.4227-4233.2000	2000
Genetics	A unique organization of the protein subunits of the DNA polymerase clamp loader in the archaeon Methanobacterium thermoautotrophicum deltaH.	Kelman Z, Hurwitz J	J Biol Chem	10.1074/jbc.275.10.7327	2000
Metabolism	The single minichromosome maintenance protein of Methanobacterium thermoautotrophicum DeltaH contains DNA helicase activity.	Kelman Z, Lee JK, Hurwitz J	Proc Natl Acad Sci U S A	10.1073/pnas.96.26.14783	1999
Enzymology	A plant-type (beta-class) carbonic anhydrase in the thermophilic methanoarchaeon Methanobacterium thermoautotrophicum.	Smith KS, Ferry JG	J Bacteriol	10.1128/JB.181.20.6247-6253.1999	1999
Enzymology	Isolation and characterization of a split B-type DNA polymerase from the archaeon Methanobacterium thermoautotrophicum deltaH.	Kelman Z, Pietrokovski S, Hurwitz J	J Biol Chem	10.1074/jbc.274.40.28751	1999
Metabolism	Methanobacterium thermoautotrophicum RNA polymerase and transcription in vitro.	Darcy TJ, Hausner W, Awery DE, Edwards AM, Thomm M, Reeve JN	J Bacteriol	10.1128/JB.181.14.4424-4429.1999	1999
Enzymology	Two malate dehydrogenases in Methanobacterium thermoautotrophicum.	Thompson H, Tersteegen A, Thauer RK, Hedderich R	Arch Microbiol	10.1007/s002030050612	1998
Phylogeny	Isolation and characterization of Methanobacterium thermoautotrophicum DeltaH mutants unable to grow under hydrogen-deprived conditions.	Pennings JL, Keltjens JT, Vogels GD	J Bacteriol	10.1128/JB.180.10.2676-2681.1998	1998
Metabolism	Methanopterin biosynthesis: methylation of the biosynthetic intermediates.	White RH	Biochim Biophys Acta	10.1016/s0304-4165(97)00148-7	1998
Enzymology	Purification, regulation, and molecular and biochemical characterization of pyruvate carboxylase from Methanobacterium thermoautotrophicum strain deltaH.	Mukhopadhyay B, Stoddard SF, Wolfe RS	J Biol Chem	10.1074/jbc.273.9.5155	1998
	Identification, Biosynthesis, and Function of 1,3,4,6-Hexanetetracarboxylic Acid in Methanobacterium thermoautotrophicum DeltaH.	Gorkovenko A, Roberts MF, White RH	Appl Environ Microbiol	10.1128/aem.60.4.1249-1253.1994	1994
Phylogeny	DNA relatedness among some thermophilic members of the genus Methanobacterium: emendation of the species Methanobacterium thermoautotrophicum and rejection of Methanobacterium thermoformicicum as a synonym of Methanobacterium thermoautotrophicum.	Touzel JP, Conway de Macario E, Nolling J, De Vos WM, Zhilina T, Lysenko AM	Int J Syst Bacteriol	10.1099/00207713-42-3-408	1992
	Enrichment of Thermophilic Propionate-Oxidizing Bacteria in Syntrophy with Methanobacterium thermoautotrophicum or Methanobacterium thermoformicicum.	Stams AJ, Grolle KC, Frijters CT, Van Lier JB	Appl Environ Microbiol	10.1128/aem.58.1.346-352.1992	1992
Metabolism	Diversity and population dynamics of methanogenic bacteria in a granular consortium.	Visser FA, van Lier JB, Macario AJ, Conway de Macario E	Appl Environ Microbiol	10.1128/aem.57.6.1728-1734.1991	1991
	Hydrogen partial pressures in a thermophilic acetate-oxidizing methanogenic coculture.	Lee MJ, Zinder SH	Appl Environ Microbiol	10.1128/aem.54.6.1457-1461.1988	1988
Biotechnology	Production of ethane, ethylene, and acetylene from halogenated hydrocarbons by methanogenic bacteria.	Belay N, Daniels L	Appl Environ Microbiol	10.1128/aem.53.7.1604-1610.1987	1987
	Comparison of assimilatory organic nitrogen, sulfur, and carbon sources for growth of methanobacterium species.	Bhatnagar L, Jain MK, Aubert JP, Zeikus JG	Appl Environ Microbiol	10.1128/aem.48.4.785-790.1984	1984
Enzymology	A plasmid in the archaebacterium Methanobacterium thermoautotrophicum.	Meile L, Kiener A, Leisinger T	Mol Gen Genet	10.1007/BF00425766	1983
Enzymology	Paramagnetic centers in the nickel-containing, deazaflavin-reducing hydrogenase from Methanobacterium thermoautotrophicum.	Kojima N, Fox JA, Hausinger RP, Daniels L, Orme-Johnson WH, Walsh C	Proc Natl Acad Sci U S A	10.1073/pnas.80.2.378	1983
Enzymology	Microbiology of methanogenesis in thermal, volcanic environments.	Zeikus JG, Ben-Bassat A, Hegge PW	J Bacteriol	10.1128/jb.143.1.432-440.1980	1980
Metabolism	Functional Characterization and Screening of Promiscuous Kinases and Isopentenyl Phosphate Kinases for the Synthesis of DMAPP via a One-Pot Enzymatic Cascade.	Qiu C, Liu Y, Wu Y, Zhao L, Pei J	Int J Mol Sci	10.3390/ijms232112904	2022
Pathogenicity	An Interdomain Conjugation Protocol for Plasmid-DNA Transfer into Methanothermobacter thermautotrophicus DeltaH.	Fink C, Angenent LT, Molitor B	Methods Mol Biol	10.1007/978-1-0716-2445-6_7	2022
Metabolism	Syntrophorhabdus aromaticivorans gen. nov., sp. nov., the first cultured anaerobe capable of degrading phenol to acetate in obligate syntrophic associations with a hydrogenotrophic methanogen.	Qiu YL, Hanada S, Ohashi A, Harada H, Kamagata Y, Sekiguchi Y.	Appl Environ Microbiol	10.1128/aem.02378-07	2008
Phylogeny	Fidelibacter multiformis gen. nov., sp. nov., isolated from a deep subsurface aquifer and proposal of Fidelibacterota phyl. nov., formerly called Marine Group A, SAR406 or Candidatus Marinimicrobia.	Katayama T, Nobu MK, Kamagata Y, Tamaki H.	Int J Syst Evol Microbiol	10.1099/ijsem.0.006558	2024
	A novel interdomain consortium from a Costa Rican oil well composed of Methanobacterium cahuitense sp. nov. and Desulfomicrobium aggregans sp. nov.	Dengler L, Meier J, Klingl A, Nissl L, Bellack A, Grohmann D, Rachel R, Huber H.	Arch Microbiol	10.1007/s00203-023-03533-9	2023
Phylogeny	Tepidanaerobacter syntrophicus gen. nov., sp. nov., an anaerobic, moderately thermophilic, syntrophic alcohol- and lactate-degrading bacterium isolated from thermophilic digested sludges.	Sekiguchi Y, Imachi H, Susilorukmi A, Muramatsu M, Ohashi A, Harada H, Hanada S, Kamagata Y.	Int J Syst Evol Microbiol	10.1099/ijs.0.64112-0	2006
Phylogeny	Phylogenetic analysis of 18 thermophilic Methanobacterium isolates supports the proposals to create a new genus, Methanothermobacter gen. nov., and to reclassify several isolates in three species, Methanothermobacter thermautotrophicus comb. nov., Methanothermobacter wolfeii comb. nov., and Methanothermobacter marburgensis sp. nov.	Wasserfallen A, Nolling J, Pfister P, Reeve J, Conway de Macario E.	Int J Syst Evol Microbiol	10.1099/00207713-50-1-43	2000
Phylogeny	Thermoanaerosceptrum fracticalcis gen. nov. sp. nov., a Novel Fumarate-Fermenting Microorganism From a Deep Fractured Carbonate Aquifer of the US Great Basin.	Hamilton-Brehm SD, Stewart LE, Zavarin M, Caldwell M, Lawson PA, Onstott TC, Grzymski J, Neveux I, Lollar BS, Russell CE, Moser DP.	Front Microbiol	10.3389/fmicb.2019.02224	2019
Phylogeny	Zhaonella formicivorans gen. nov., sp. nov., an anaerobic formate-utilizing bacterium isolated from Shengli oilfield, and proposal of four novel families and Moorellales ord. nov. in the phylum Firmicutes.	Lv XM, Yang M, Dai LR, Tu B, Chang C, Huang Y, Deng Y, Lawson PA, Zhang H, Cheng L, Tang YQ	Int J Syst Evol Microbiol	10.1099/ijsem.0.004178	2020
Phylogeny	Methanothermobacter tenebrarum sp. nov., a hydrogenotrophic, thermophilic methanogen isolated from gas-associated formation water of a natural gas field.	Nakamura K, Takahashi A, Mori C, Tamaki H, Mochimaru H, Nakamura K, Takamizawa K, Kamagata Y	Int J Syst Evol Microbiol	10.1099/ijs.0.041681-0	2012
Phylogeny	Isolation and characterization of Methanothermobacter crinale sp. nov., a novel hydrogenotrophic methanogen from the Shengli oil field.	Cheng L, Dai L, Li X, Zhang H, Lu Y	Appl Environ Microbiol	10.1128/AEM.00210-11	2011
Phylogeny	Thermosyntropha tengcongensis sp. nov., a thermophilic bacterium that degrades long-chain fatty acids syntrophically.	Zhang F, Liu X, Dong X	Int J Syst Evol Microbiol	10.1099/ijs.0.033456-0	2011
Phylogeny	Thermodesulfovibrio aggregans sp. nov. and Thermodesulfovibrio thiophilus sp. nov., anaerobic, thermophilic, sulfate-reducing bacteria isolated from thermophilic methanogenic sludge, and emended description of the genus Thermodesulfovibrio.	Sekiguchi Y, Muramatsu M, Imachi H, Narihiro T, Ohashi A, Harada H, Hanada S, Kamagata Y	Int J Syst Evol Microbiol	10.1099/ijs.0.2008/000893-0	2008

References

#387	Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 1053
#20215	Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 )
#66792	Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) .
#67770	Japan Collection of Microorganism (JCM) ; Curators of the JCM;
#125438	Julia Koblitz, Lorenz Christian Reimer, Rüdiger Pukall, Jörg Overmann: Predicting bacterial phenotypic traits through improved machine learning using high-quality, curated datasets. 2024 ( DOI 10.1101/2024.08.12.607695 )
#125439	Philipp Münch, René Mreches, Martin Binder, Hüseyin Anil Gündüz, Xiao-Yin To, Alice McHardy: deepG: Deep Learning for Genome Sequence Data. R package version 0.3.1 .
#126262	A. Lissin, I. Schober, J. F. Witte, H. Lüken, A. Podstawka, J. Koblitz, B. Bunk, P. Dawyndt, P. Vandamme, P. de Vos, J. Overmann, L. C. Reimer: StrainInfo—the central database for linked microbial strain identifiers. ( DOI 10.1093/database/baaf059 )

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Methanobacterium thermautotrophicum (DSM 1053, ATCC 29096, JCM 10044)

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