Leuconostoc lactis (DSM 8581, JCM 11052, CCUG 38887)

Name: Leuconostoc lactis (DSM 8581, JCM 11052, CCUG 38887)
Creator: BacDive
License: http://creativecommons.org/licenses/by/4.0/

BacDive ID 6814

Type strain

Strain Designation LL76

Variant Isotype of BacDive ID 137658

Culture col. no. DSM 8581 JCM 11052 CCUG 38887 CECT 5746 LL76 3 more

NCBI tax ID(s) 886872 1246

Special Collections DSMZ CCUG JCM KCTC CIP

History <- L.M.T. Dicks <- F. Dellaglio <- F.C. Gonzalez et al., LL76 DSM 8581 <-- L. M. T. Dicks LL76 <-- F. Dellaglio <-- F. C. Gonzalez. CIP <- 1993, L.M.T. Dicks, Food Ind. Microbiol., Stellenbosch, South Africa, Leuconostoc argentinum: strain LL76 <- F. Dellaglio <- F.C. Gonzales

Links

Leuconostoc lactis LL76 is an anaerobe, Gram-positive, coccus-shaped bacterium that was isolated from raw milk.

Gram-positive coccus-shaped anaerobe genome sequence 16S sequence Bacteria

Name and taxonomic classification

SI-ID 12409

LMG 18543,CCUG 38887,CIP 103889,JCM 11052,KCTC 3773,CECT 5746,DSM 8581

@ref 20215

Last LPSN update 2026-02-09 11:19:19

Domain Bacteria

Phylum Bacillota

Class Bacilli

Order Lactobacillales

Family Lactobacillaceae

Genus Leuconostoc

Species Leuconostoc lactis

Full scientific name Leuconostoc lactis Garvie 1960 (Approved Lists 1980)

Synonyms (1)

Leuconostoc argentinum

BacDive ID	Other strains from **Leuconostoc lactis** (36)	Type strain
6818	L. lactis CCUG 30064, NRRL B-3468, DSM 20202, ATCC ... (type strain)
6815	L. lactis LL80, DSM 8582, ATCC 51354
6816	L. lactis LL84, DSM 8583
6817	L. lactis Zg V1, DSM 20192, CCUG 21964, LMG 7940t2, ...
135006	L. lactis 130.87, CIP 102869
135007	L. lactis 129.87, CIP 102870
135836	L. lactis CIP 101238
135837	L. lactis CIP 101240
136023	L. lactis CIP 101878
137658	L. lactis CIP 103889, LMG 18543
137868	L. lactis CIP 101991
137909	L. lactis 103-86, CIP 102167
137993	L. lactis CIP 102427
138712	L. lactis CIP 102307
139185	L. lactis CIP 100915
139199	L. lactis CIP 101268
141962	L. lactis CCUG 8883 B
145815	L. lactis CCUG 29681
146667	L. lactis CCUG 31753
149204	L. lactis CCUG 37264
149290	L. lactis CCUG 37427 A
149543	L. lactis CCUG 37937
149671	L. lactis CCUG 38156
150273	L. lactis CCUG 39462
151319	L. lactis CCUG 43736
151328	L. lactis CCUG 43770
151780	L. lactis CCUG 44865
152345	L. lactis CCUG 46478
153372	L. lactis CCUG 49364
154775	L. lactis CCUG 55147
155335	L. lactis CCUG 57361
155984	L. lactis CCUG 59883
161159	L. lactis JCM 1142, ATCC 15520, IAM 10063, JCM 20305, ...
162860	L. lactis JCM 20305
173140	L. lactis CRBIP24.147
173141	L. lactis 536, CRBIP24.167

Morphology

Cell morphology

@ref	Gram stain	Cell shape	Confidence
38487	positive	coccus-shaped
125438			91.5
125438	positive		93.714

Culture and growth conditions

Culture medium

@ref	Name	Growth	Medium link	Composition
3310	MRS MEDIUM (DSMZ Medium 11)		Medium recipe at MediaDive	Name: MRS MEDIUM (DSMZ Medium 11) Composition: Glucose 20.0 g/l Casein peptone 10.0 g/l Meat extract 10.0 g/l Na-acetate 5.0 g/l Yeast extract 5.0 g/l (NH4)3 citrate 2.0 g/l K2HPO4 2.0 g/l Tween 80 1.0 g/l MgSO4 x 7 H2O 0.2 g/l MnSO4 x H2O 0.05 g/l Distilled water
38487	CIP Medium 40		Medium recipe at CIP

Culture temp

@ref	Growth	Type	Temperature (°C)
3310	positive	growth	30
38487	positive	growth	10-41
38487	negative	growth	5
38487	negative	growth	44
54529	positive	growth	30
54529	positive	growth	30-37
67770	positive	growth	30

Physiology and metabolism

Oxygen tolerance

@ref	Oxygen tolerance	Confidence
54529	anaerobe
54529	microaerophile
38487	facultative anaerobe
125439	microaerophile	93.6

Murein

@ref	Murein short key	Type
3310	A11.05	A3alpha L-Lys-L-Ala₂

Metabolite utilization

@ref	Chebi-ID	Metabolite	Utilization activity	Kind of utilization tested
68371	17108 ChEBI	D-arabinose	-	builds acid from	from API 50CH acid
68371	18333 ChEBI	D-arabitol	-	builds acid from	from API 50CH acid
68371	28847 ChEBI	D-fucose	-	builds acid from	from API 50CH acid
68371	62318 ChEBI	D-lyxose	-	builds acid from	from API 50CH acid
68371	17924 ChEBI	D-sorbitol	-	builds acid from	from API 50CH acid
68371	65327 ChEBI	D-xylose	-	builds acid from	from API 50CH acid
68371	17113 ChEBI	erythritol	-	builds acid from	from API 50CH acid
38487	4853 ChEBI	esculin	-	hydrolysis
68371	16813 ChEBI	galactitol	-	builds acid from	from API 50CH acid
68371	24265 ChEBI	gluconate	-	builds acid from	from API 50CH acid
68371	17754 ChEBI	glycerol	-	builds acid from	from API 50CH acid
68371	28087 ChEBI	glycogen	-	builds acid from	from API 50CH acid
68371	15443 ChEBI	inulin	-	builds acid from	from API 50CH acid
68371	18403 ChEBI	L-arabitol	-	builds acid from	from API 50CH acid
68371	18287 ChEBI	L-fucose	-	builds acid from	from API 50CH acid
68371	62345 ChEBI	L-rhamnose	-	builds acid from	from API 50CH acid
68371	17266 ChEBI	L-sorbose	-	builds acid from	from API 50CH acid
68371	65328 ChEBI	L-xylose	-	builds acid from	from API 50CH acid
68371	6731 ChEBI	melezitose	-	builds acid from	from API 50CH acid
68371	320061 ChEBI	methyl alpha-D-glucopyranoside	-	builds acid from	from API 50CH acid
68371	43943 ChEBI	methyl alpha-D-mannoside	-	builds acid from	from API 50CH acid
68371	74863 ChEBI	methyl beta-D-xylopyranoside	-	builds acid from	from API 50CH acid
68371	17268 ChEBI	myo-inositol	-	builds acid from	from API 50CH acid
38487	17632 ChEBI	nitrate	-	reduction
38487	16301 ChEBI	nitrite	-	reduction
68371		Potassium 2-ketogluconate	-	builds acid from	from API 50CH acid
68371		Potassium 5-ketogluconate	-	builds acid from	from API 50CH acid
68371	16634 ChEBI	raffinose	-	builds acid from	from API 50CH acid
68371	15963 ChEBI	ribitol	-	builds acid from	from API 50CH acid
68371	28017 ChEBI	starch	-	builds acid from	from API 50CH acid
68371	32528 ChEBI	turanose	-	builds acid from	from API 50CH acid
68371	17151 ChEBI	xylitol	-	builds acid from	from API 50CH acid

Antibiotic resistance

@ref	Metabolite	Is sensitive	Is resistant
38487	0129 (2,4-Diamino-6,7-di-iso-propylpteridine phosphate)

Metabolite tests

@ref	Chebi-ID	Metabolite	Voges-proskauer-test
38487	15688 ChEBI	acetoin	-

Enzymes

@ref	Value	Activity	Ec
38487	alcohol dehydrogenase	+	1.1.1.1
38487	catalase	-	1.11.1.6
38487	lysine decarboxylase	-	4.1.1.18
38487	ornithine decarboxylase	-	4.1.1.17
38487	oxidase	-

API 50CHac

@ref	ControlQ	GLY	ERY	DARA	LARA	RIB	DXYL	LXYL	ADO	MDX	GAL	GLU	FRU	MNE	SBE	RHA	DUL	INO	MAN	SOR	MDM	MDG	NAG	AMY	ARB	ESC	SAL	CEL	MAL	LAC	MEL	SAC	TRE	INU	MLZ	RAF	AMD	GLYG	XLT	GEN	TUR	LYX	TAG	DFUC	LFUC	DARL	LARL	GNT	2KG	5KG
38487	not determinedn.d.	-	-	-	+/-	+/-	-	-	-	-	+/-	+/-	+/-	+/-	-	-	-	-	+/-	-	-	-	+/-	+/-	+/-	+/-	+/-	+/-	+/-	+/-	+/-	+/-	+/-	-	-	-	-	-	-	+/-	-	-	+/-	-	-	-	-	-	-	-

Isolation, sampling and environmental information

Isolation source categories

Cat1	Cat2	Cat3
#Host Body Product	#Fluids	#Milk
#Host	#Mammals	-

Isolation

@ref	Sample type	Country	Country ISO 3 Code	Continent
3310	raw milk	Argentina	ARG	Middle and South America
54529	Milk,raw	Argentina	ARG	Middle and South America
67770	Argentine raw milk
38487	Food, Raw milk	Argentina	ARG	Middle and South America

Taxonmaps

69479

Global distribution of 16S sequence LC260036 (>99% sequence identity) for Leuconostoc from Microbeatlas

Aquatic Samples	3705
Soil Samples	2149
Animal Samples	23973
Plant Samples	1253
Total Samples	31080

Interaction and safety

Risk assessment

@ref	Pathogenicity human	Biosafety level	Biosafety level comment
3310	yes, in single cases	1	Risk group (German classification) According to TRBA 466
38487		1	Risk group (French classification) According to TRBA 466

Sequence information

Genome sequences

@ref	Description	Assembly level	INSDC accession	BV-BRC accession	IMG accession	NCBI tax ID	Score
66792	ASM17987v1 assembly for Leuconostoc lactis KCTC 3773	contig	GCA_000179875	886872.3	651324066	886872	59.59

16S sequences

@ref	Description	Accession	Length	Database	NCBI tax ID
20218	Leuconostoc argentinum 16S ribosomal RNA gene, partial sequence	AF175403	1471		886872
67770	Leuconostoc lactis gene for 16S ribosomal RNA, partial sequence, strain: JCM 11052	LC260036	1485		1246

GC content

@ref	GC-content (mol%)	Method
3310	41.0	thermal denaturation, midpoint method (Tm)
67770	40.5	high performance liquid chromatography (HPLC)

Genome-based predictions

Predictions

Predictions from Deep Learning for Genome Sequence Data. R package version 0.3.1 based on: Leuconostoc lactis KCTC 3773
NCBI: GCA_000179875

@ref	Trait	Model	Prediction	Confidence in %	In training data
125439	spore_formation	BacteriaNetⓘ	no	61.80	no
125439	motility	BacteriaNetⓘ	no	59.90	no
125439	gram_stain	BacteriaNetⓘ	positive	85.60	no
125439	oxygen_tolerance	BacteriaNetⓘ	microaerophile	93.60	no

Predictions from bacterial phenotypic traits through improved machine learning using high-quality, curated datasets based on: Leuconostoc argentinum KCTC 3773
PATRIC: 886872.3

@ref	Trait	Model	Prediction	Confidence in %	In training data
125438	gram-positive	gram-positiveⓘ	yes	93.71	no
125438	anaerobic	anaerobicⓘ	no	83.09	no
125438	aerobic	aerobicⓘ	no	93.78	yes
125438	spore-forming	spore-formingⓘ	no	87.20	no
125438	thermophilic	thermophileⓘ	no	96.00	yes
125438	flagellated	motile2+ⓘ	no	91.50	no

Literature

Topic	Title	Authors	Journal	DOI	Year
Enzymology	Diversity of anaerobic microbes in spacecraft assembly clean rooms.	Probst A, Vaishampayan P, Osman S, Moissl-Eichinger C, Andersen GL, Venkateswaran K.	Appl Environ Microbiol	10.1128/aem.02167-09	2010
	Development of innovative pediocin PA-1 by DNA shuffling among class IIa bacteriocins.	Tominaga T, Hatakeyama Y.	Appl Environ Microbiol	10.1128/aem.00558-07	2007
Genetics	Comparative genomics of Leuconostoc lactis strains isolated from human gastrointestinal system and fermented foods microbiomes.	Gumustop I, Ortakci F.	BMC Genom Data	10.1186/s12863-022-01074-6	2022
Phylogeny	Phylogenomic analysis of the genus Leuconostoc.	Raimondi S, Candeliere F, Amaretti A, Costa S, Vertuani S, Spampinato G, Rossi M.	Front Microbiol	10.3389/fmicb.2022.897656	2022
	Evaluation of antimicrobial efficacy against spoilage microorganisms and impact on beverage color and turbidity of commercial preservatives derived from edible mushrooms.	Galasong Y, Charles-Vegdahl A, Worobo RW.	Int J Food Microbiol	10.1016/j.ijfoodmicro.2025.111130	2025
	Hydrolysis of oligosaccharides in the gastrointestinal tract alters their prebiotic effects on probiotic strains.	Lee WM, Song YB, Han KS, Sim WS, Lee BH.	Food Sci Biotechnol	10.1007/s10068-023-01474-z	2024
	In Vitro Prebiotic Potential of Opuntia humifusa Leaf Extract and Its Active Constituent	Ko M, Eom D, Lee C, Park T, Lee S, Kim C, Moon H, Lee S, Hwang K, Park S.	Molecules		2025
	Assessment of the feed additive consisting of Enterococcus lactis DSM 7134 (Bonvital®) for sows for the renewal of its authorisation (Lactosan GmbH & Co.KG).	EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Villa RE, Azimonti G, Bonos E, Christensen H, Durjava M, Dusemund B, Gehring R, Glandorf B, Kouba M, Lopez-Alonso M, Marcon F, Nebbia C, Pechova A, Prieto-Maradona M, Rohe I, Theodoridou K, Cocconcelli PS, Anguita M, Galobart J, Innocenti ML, Brozzi R.	EFSA J	10.2903/j.efsa.2025.9353	2025
	Complete Genome Sequence of Lactobacillus hilgardii LMG 7934, Carrying the Gene Encoding for the Novel PII-Like Protein PotN.	Zhuravleva DE, Iskhakova ZI, Ozhegov GD, Gogoleva NE, Khusnutdinova DR, Shagimardanova EI, Forchhammer K, Kayumov AR.	Curr Microbiol	10.1007/s00284-020-02161-6	2020
	Assessment of Antimicrobial Activity and Safety of Pediococcus pentosaceus Isolated from Ginseng as a Functional Cosmetic Ingredient.	Jin X, Zheng Q, Nguyen TTM, Yi GS, Yang SJ, Yi TH.	Microorganisms	10.3390/microorganisms13051093	2025
	Characterization of an Aminopeptidase A from Tetragenococcus halophilus CY54 Isolated from Myeolchi-Jeotgal.	Kim TJ, Kim MJ, Kang YJ, Yoo JY, Kim JH.	J Microbiol Biotechnol	10.4014/jmb.2210.10003	2023
	Lipoteichoic Acid from Lacticaseibacillus rhamnosus GG as a Novel Intracanal Medicament Targeting Enterococcus faecalis Biofilm Formation.	Yoon JY, Park S, Lee D, Park OJ, Lee W, Han SH.	J Microbiol	10.1007/s12275-024-00165-6	2024
Pathogenicity	Anti-Inflammatory and Prebiotic Potential of Ethanol Extracts and Mucilage Polysaccharides from Korean Yams (Dioscorea polystachya and Dioscorea bulbifera).	Park SY, Truong VL, Jeon SG, Choe SY, Rarison RHG, Yoon BH, Park JW, Jeong HJ, Jeong WS.	Foods	10.3390/foods14020173	2025
Cultivation	Evaluation of Different Nutritional Sources in Lactic Acid Bacteria Fermentation for Sustainable Postbiotic Production.	Garrote Achou C, Cantalejo Diez MJ, Diaz Cano J, Molinos Equiza X.	Foods	10.3390/foods14040649	2025
Genetics	Functional genomic insights into Floricoccus penangensis ML061-4 isolated from leaf surface of Assam tea.	Rungsirivanich P, Parlindungan E, Mahony J, Supandee W, Thongwai N, van Sinderen D.	Sci Rep	10.1038/s41598-025-86602-x	2025
	Inhibition of Differentiation of 3T3-L1 Cells by Increasing Glioma-Associated Oncogene Expression in Chrysanthemum indicum L. Using Lactococcus lactis KCTC 3115.	Cho YJ, Lee JB, Lee Y, Lee MS, Choi J.	Prev Nutr Food Sci	10.3746/pnf.2024.29.4.533	2024
Biotechnology	Probiotic potential of ginseng derived Lacticaseibacillus rhamnosus strains with hypocholesterolemic, antioxidant and antibacterial activities	Ahmed E, Lee J, Hamayun M, Jung S, Kim H, Lee B.	Sci Rep		2025
	Safety and efficacy of a feed additive consisting of Lactococcus lactis DSM 34262 as a silage additive for all animal species (Lactosan GmbH & Co.KG).	EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Bampidis V, Azimonti G, Bastos ML, Christensen H, Durjava M, Dusemund B, Kouba M, Lopez-Alonso M, Lopez Puente S, Marcon F, Mayo B, Pechova A, Petkova M, Ramos F, Villa RE, Woutersen R, Anguita M, Bozzi Cionci N, Brozzi R, Innocenti ML, Ortuno J, Tarres-Call J, Valeri P, Garcia-Cazorla Y.	EFSA J	10.2903/j.efsa.2024.8902	2024
	Microbiome-Based Products: Therapeutic Potential for Inflammatory Skin Diseases.	Rusanac A, Skibola Z, Matijasic M, Cipcic Paljetak H, Peric M.	Int J Mol Sci	10.3390/ijms26146745	2025
Metabolism	Nisin production in realkalized fed-batch cultures in whey with feeding with lactose- or glucose-containing substrates.	Costas Malvido M, Alonso Gonzalez E, Perez Guerra N.	Appl Microbiol Biotechnol	10.1007/s00253-016-7558-9	2016
	Assessment of the feed additive consisting of Enterococcus lactis DSM 7134 and Lacticaseibacillus rhamnosus DSM 7133 (Provita LE) for calves for rearing for the renewal of its authorisation (Lactosan GmbH & Co.KG).	EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Bampidis V, Azimonti G, Bastos ML, Christensen H, Durjava M, Dusemund B, Kouba M, Lopez-Alonso M, Lopez Puente S, Marcon F, Mayo B, Pechova A, Petkova M, Ramos F, Villa RE, Woutersen R, Alija Novo N, Anguita M, Brozzi R, Tarres-Call J.	EFSA J	10.2903/j.efsa.2023.8350	2023
Enzymology	Identification of a staphylococcal dipeptidase involved in the production of human body odor.	Herman R, Kinniment-Williams B, Rudden M, James AG, Wilkinson AJ, Murphy B, Thomas GH.	J Biol Chem	10.1016/j.jbc.2024.107928	2024
Pathogenicity	A multistrategic approach in the development of sourdough bread targeted towards blood pressure reduction.	Penas E, Diana M, Frias J, Quilez J, Martinez-Villaluenga C.	Plant Foods Hum Nutr	10.1007/s11130-015-0469-6	2015
	Assessment of the feed additive consisting of Enterococcus lactisDSM 7134 (Bonvital®) for chickens reared for laying and minor poultry species other than those used for laying for the renewal of its authorisation (Lactosan GmbH & Co.KG).	EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Bampidis V, Azimonti G, Bastos ML, Christensen H, Durjava M, Dusemund B, Kouba M, Lopez-Alonso M, Lopez Puente S, Marcon F, Mayo B, Pechova A, Petkova M, Ramos F, Villa RE, Woutersen R, Alija-Novo N, Anguita M, Brozzi R.	EFSA J	10.2903/j.efsa.2023.8351	2023
	Specificity of the AMP-6000 Method for Enumerating Clostridium Endospores in Milk.	Burtscher J, Rudavsky T, Zitz U, Domig KJ.	Foods	10.3390/foods13081192	2024
	Psychobiotics Ameliorate Depression and Anxiety Status in Surgical Oncology Patients: Results from the ProDeCa Study.	Tzikos G, Chamalidou E, Christopoulou D, Apostolopoulou A, Gkarmiri S, Pertsikapa M, Menni AE, Theodorou IM, Stavrou G, Doutsini ND, Shrewsbury AD, Papavramidis T, Tsetis JK, Theodorou H, Konsta A, Kotzampassi K.	Nutrients	10.3390/nu17050857	2025
	Rewiring Mood: Precision Psychobiotics as Adjunct or Stand-Alone Therapy in Depression Using Insights from 19 Randomized Controlled Trials in Adults.	Menni AE, Theodorou H, Tzikos G, Theodorou IM, Semertzidou E, Stelmach V, Shrewsbury AD, Stavrou G, Kotzampassi K.	Nutrients	10.3390/nu17122022	2025
Pathogenicity	Modulation of miR-29a and miR-29b Expression and Their Target Genes Related to Inflammation and Renal Fibrosis by an Oral Nutritional Supplement with Probiotics in Malnourished Hemodialysis Patients.	Sasso CV, Lhamyani S, Hevilla F, Padial M, Blanca M, Barril G, Jimenez-Salcedo T, Martinez ES, Nogueira A, Lago-Sampedro AM, Olveira G.	Int J Mol Sci	10.3390/ijms25021132	2024
	Identification of FtfL as a novel target of berberine in intestinal bacteria.	Yan J, Fang C, Yang G, Li J, Liu Y, Zhang L, Yang P, Fang J, Gu Y, Zhang Y, Jiang W.	BMC Biol	10.1186/s12915-023-01778-w	2023
	The role of Bifidobacterium in longevity and the future of probiotics.	Ku S, Haque MA, Jang MJ, Ahn J, Choe D, Jeon JI, Park MS.	Food Sci Biotechnol	10.1007/s10068-024-01631-y	2024
	Evaluation of the Probiotic Properties of Lacticaseibacillus casei 431^® Isolated from Food for Special Medical Purposes^§.	Lebos Pavunc A, Penava L, Culjak N, Banic M, Novak J, Butorac K, Ceilinger M, Milicevic J, Cukelj D, Suskovic J, Kos B.	Food Technol Biotechnol	10.17113/ftb.61.04.23.8045	2023
	Evaluation of two bacteriocin-producing probiotic lactic acid bacteria as inoculants for controlling Listeria monocytogenes in grass and maize silages	Amado IR, Fucinos C, Fajardo P, Guerra NP, Pastrana L.	Anim Feed Sci Technol	10.1016/j.anifeedsci.2012.05.006	2012
	Genome Sequence of Salegentibacter mishustinae KCTC 12263, Containing a Complete Subtype I-B CRISPR-Cas System.	Zhang F, Lin W, Zhang R, Zheng Q, Jiao N.	Genome Announc	10.1128/genomea.00267-16	2016
Pathogenicity	Anti-Inflammation and Anti-Melanogenic Effects of Maca Root Extracts Fermented Using Lactobacillus Strains.	Yang J, Cho H, Gil M, Kim KE.	Antioxidants (Basel)	10.3390/antiox12040798	2023
	Heat-killed Limosilactobacillus reuteri PSC102 Ameliorates Impaired Immunity in Cyclophosphamide-induced Immunosuppressed Mice.	Ali MS, Lee EB, Quah Y, Birhanu BT, Suk K, Lim SK, Park SC.	Front Microbiol	10.3389/fmicb.2022.820838	2022
	Protist-Lactic Acid Bacteria Co-Culture as a Strategy to Bioaccumulate Polyunsaturated Fatty Acids in the Protist Aurantiochytrium sp. T66.	Marileo L, Acuna J, Rilling J, Diaz P, Langellotti AL, Russo GL, Barra PJ, Dantagnan P, Viscardi S.	Mar Drugs	10.3390/md21030142	2023
	Production of Reduced Graphene Oxide by Using Three Different Microorganisms and Investigation of Their Cell Interactions.	Utkan G, Yumusak G, Tunali BC, Ozturk T, Turk M.	ACS Omega	10.1021/acsomega.3c03213	2023
Pathogenicity	Heat-Killed Lactobacillus brevis Enhances Phagocytic Activity and Generates Immune-Stimulatory Effects through Activating the TAK1 Pathway.	Jeong M, Kim JH, Lee JS, Kang SD, Shim S, Jung MY, Yang H, Byun S, Lee KW.	J Microbiol Biotechnol	10.4014/jmb.2002.02004	2020
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	Alginate- and Gelatin-Coated Apple Pieces as Carriers for Bifidobacterium animalis subsp. lactis DSM 10140.	Campaniello D, Bevilacqua A, Speranza B, Sinigaglia M, Corbo MR.	Front Microbiol	10.3389/fmicb.2020.566596	2020
	Effect of Lactobacillus cultures on microbiological, chemical and odour changes during storage of rainbow trout fillets	Katikou P, Ambrosiadis I, Georgantelis D, Koidis P, Georgakis SA.	J Sci Food Agric	10.1002/jsfa.2736	2007
	Probiotic and postbiotic analytical methods: a perspective of available enumeration techniques.	Boyte ME, Benkowski A, Pane M, Shehata HR.	Front Microbiol	10.3389/fmicb.2023.1304621	2023
	Valorizing cabbage (Brassica oleracea L. var. capitata) and capsicum (Capsicum annuum L.) wastes: in vitro health-promoting activities.	Liang JL, Yeow CC, Teo KC, Gnanaraj C, Chang YP.	J Food Sci Technol	10.1007/s13197-019-03912-5	2019
Biotechnology	Relation of biogenic amines' formation with microbiological and sensory attributes in Lactobacillus-inoculated vacuum-packed rainbow trout (Oncorhynchus mykiss) fillets.	Katikou P, Georgantelis D, Paleologos EK, Ambrosiadis I, Kontominas MG.	J Agric Food Chem	10.1021/jf0602121	2006
	Characterization and cytotoxicity assessment of biosurfactant derived from Lactobacillus pentosus NCIM 2912.	Sharma V, Singh D, Manzoor M, Banpurkar AG, Satpute SK, Sharma D.	Braz J Microbiol	10.1007/s42770-021-00654-5	2022
	Fermentation of Cucumber Extract with Hydromagnesite as a Neutralizing Agent to Produce an Ingredient for Dermal Magnesium Products.	Nguyen VK, Tran T, Crimmins T, Luong VT, Kang HY.	Materials (Basel)	10.3390/ma12101701	2019
	Resistance of Lactobacillus casei KCTC 3260 to reactive oxygen species (ROS): role for a metal ion chelating effect	Lee J, Hwang KT, Chung MY, Cho DH, Park CS.	J Food Sci		2005
	Skin Microbiota in Atopic Dermatitis.	Hrestak D, Matijasic M, Cipcic Paljetak H, Ledic Drvar D, Ljubojevic Hadzavdic S, Peric M.	Int J Mol Sci	10.3390/ijms23073503	2022
Genetics	Genome Mining for Antimicrobial Compounds in Wild Marine Animals-Associated Enterococci.	Prichula J, Primon-Barros M, Luz RCZ, Castro IMS, Paim TGS, Tavares M, Ligabue-Braun R, d'Azevedo PA, Frazzon J, Frazzon APG, Seixas A, Gilmore MS.	Mar Drugs	10.3390/md19060328	2021
Metabolism	A Probiotic Preparation Hydrolyzes Gliadin and Protects Intestinal Cells from the Toxicity of Pro-Inflammatory Peptides.	Giorgi A, Cerrone R, Capobianco D, Filardo S, Mancini P, Zanni F, Fanelli S, Mastromarino P, Mosca L.	Nutrients	10.3390/nu12020495	2020
	Effects of Class IIa Bacteriocin-Producing Lactobacillus Species on Fermentation Quality and Aerobic Stability of Alfalfa Silage.	Li F, Ding Z, Adesogan AT, Ke W, Jiang Y, Bai J, Mudassar S, Zhang Y, Huang W, Guo X, Guo X.	Animals (Basel)	10.3390/ani10091575	2020
Pathogenicity	Effect on nutritional status and biomarkers of inflammation and oxidation of an oral nutritional supplement (with or without probiotics) in malnourished hemodialysis patients. A multicenter randomized clinical trial "Renacare Trial".	Hevilla F, Padial M, Blanca M, Barril G, Jimenez-Salcedo T, Ramirez-Ortiz M, Nogueira A, Gentile A, Garcia-Escobar E, Romero-Zerbo SY, Olveira G.	Front Nutr	10.3389/fnut.2023.1107869	2023
Biotechnology	Effect of Lactobacillus-protective cultures with bacteriocin-like inhibitory substances' producing ability on microbiological, chemical and sensory changes during storage of refrigerated vacuum-packaged sliced beef.	Katikou P, Ambrosiadis I, Georgantelis D, Koidis P, Georgakis SA.	J Appl Microbiol	10.1111/j.1365-2672.2005.02739.x	2005
	Clinical Applications of System Regulation Medicine.	Fioranelli M, Sepehri A, Roccia MG, Linda C, Rossi C, Dawodo A, Vojvodic P, Lotti J, Barygina V, Vojvodic A, Wollina U, Tirant M, Van TN, Lotti T.	Open Access Maced J Med Sci	10.3889/oamjms.2019.775	2019
	Production of a Potentially Probiotic Product for Animal Feed and Evaluation of Some of Its Probiotic Properties.	Agregan-Perez R, Alonso-Gonzalez E, Mejuto JC, Perez-Guerra N.	Int J Mol Sci	10.3390/ijms221810004	2021
Enzymology	Biochemical Basis of Xylooligosaccharide Utilisation by Gut Bacteria.	Singh RP, Bhaiyya R, Thakur R, Niharika J, Singh C, Latousakis D, Saalbach G, Nepogodiev SA, Singh P, Sharma SC, Sengupta S, Juge N, Field RA.	Int J Mol Sci	10.3390/ijms23062992	2022
	Biological activities of a garlic-Cirsium setidens Nakai blend fermented with Leuconostoc mesenteroides.	Daliri EB, Choi SI, Cho BY, Jo HY, Kim SH, Chelliah R, Rubab M, Kim JH, Oh HT, Lee OH, Oh DH.	Food Sci Nutr	10.1002/fsn3.1032	2019
Metabolism	Batch and fed-batch production of probiotic biomass and nisin in nutrient-supplemented whey media.	Malvido MC, Gonzalez EA, Bazan Tantalean DL, Bendana Jacome RJ, Guerra NP.	Braz J Microbiol	10.1007/s42770-019-00114-1	2019
	Clinical and Microbiological Effect of a Multispecies Probiotic Supplementation in Celiac Patients With Persistent IBS-type Symptoms: A Randomized, Double-Blind, Placebo-controlled, Multicenter Trial.	Francavilla R, Piccolo M, Francavilla A, Polimeno L, Semeraro F, Cristofori F, Castellaneta S, Barone M, Indrio F, Gobbetti M, De Angelis M.	J Clin Gastroenterol	10.1097/mcg.0000000000001023	2019
	Aglycone Isoflavones and Exopolysaccharides Produced by Lactobacillus acidophilus in Fermented Soybean Paste.	Kim JS, Lee JH, Surh J, Kang SA, Jang KH.	Prev Nutr Food Sci	10.3746/pnf.2016.21.2.117	2016
Metabolism	The Joint Effect of pH Gradient and Glucose Feeding on the Growth Kinetics of Lactococcus lactis CECT 539 in Glucose-Limited Fed-Batch Cultures.	Malvido MC, Gonzalez EA, Bendana Jacome RJ, Guerra NP.	Pol J Microbiol	10.33073/pjm-2019-030	2019
Phylogeny	Comparison of 16S rRNA Gene Based Microbial Profiling Using Five Next-Generation Sequencers and Various Primers.	Park C, Kim SB, Choi SH, Kim S.	Front Microbiol	10.3389/fmicb.2021.715500	2021
	Impact of Heat-Killed Lactobacillus casei Strain IMAU60214 on the Immune Function of Macrophages in Malnourished Children.	Rocha-Ramirez LM, Hernandez-Ochoa B, Gomez-Manzo S, Marcial-Quino J, Cardenas-Rodriguez N, Centeno-Leija S, Garcia-Garibay M.	Nutrients	10.3390/nu12082303	2020
	Glass bead transformation method for gram-positive bacteria.	Rattanachaikunsopon P, Phumkhachorn P.	Braz J Microbiol	10.1590/s1517-838220090004000025	2009
	Differences in folate production by bifidobacteria of different origins.	Sugahara H, Odamaki T, Hashikura N, Abe F, Xiao JZ.	Biosci Microbiota Food Health	10.12938/bmfh.2015-003	2015
	Identification of Species and Subspecies of Lactic Acid Bacteria Present in Spanish Cheeses Type "Torta" by MALDI-TOF MS and pheS gene Analyses.	Sanchez-Juanes F, Teixeira-Martin V, Gonzalez-Buitrago JM, Velazquez E, Flores-Felix JD.	Microorganisms	10.3390/microorganisms8020301	2020
	Effect of Oral Administration of a Mixture of Probiotic Strains on SCORAD Index and Use of Topical Steroids in Young Patients With Moderate Atopic Dermatitis: A Randomized Clinical Trial.	Navarro-Lopez V, Ramirez-Bosca A, Ramon-Vidal D, Ruzafa-Costas B, Genoves-Martinez S, Chenoll-Cuadros E, Carrion-Gutierrez M, Horga de la Parte J, Prieto-Merino D, Codoner-Cortes FM.	JAMA Dermatol	10.1001/jamadermatol.2017.3647	2018
	Enhanced Bacteriocin Production by Pediococcus pentosaceus 147 in Co-culture With Lactobacillus plantarum LE27 on Cheese Whey Broth.	Gutierrez-Cortes C, Suarez H, Buitrago G, Nero LA, Todorov SD.	Front Microbiol	10.3389/fmicb.2018.02952	2018
Pathogenicity	Antimicrobial and Antibiofilm Activities of Sulfated Polysaccharides from Marine Algae against Dental Plaque Bacteria.	Jun JY, Jung MJ, Jeong IH, Yamazaki K, Kawai Y, Kim BM.	Mar Drugs	10.3390/md16090301	2018
	Microbial biocatalysis of quercetin-3-glucoside and isorhamnetin-3-glucoside in Salicornia herbacea and their contribution to improved anti-inflammatory activity.	Ahn HJ, You HJ, Park MS, Li Z, Choe D, Johnston TV, Ku S, Ji GE.	RSC Adv	10.1039/c9ra08059g	2020
	Probiotics in Celiac Disease.	Cristofori F, Indrio F, Miniello VL, De Angelis M, Francavilla R.	Nutrients	10.3390/nu10121824	2018
	Production of a highly concentrated probiotic culture of Lactococcus lactis CECT 539 containing high amounts of nisin.	Costas Malvido M, Alonso Gonzalez E, Outeirino D, Perez Guerra N.	3 Biotech	10.1007/s13205-018-1318-8	2018
	The Impact of Low-FODMAPs, Gluten-Free, and Ketogenic Diets on Gut Microbiota Modulation in Pathological Conditions.	Reddel S, Putignani L, Del Chierico F.	Nutrients	10.3390/nu11020373	2019
	Effect of Functional Bread Rich in Potassium, gamma-Aminobutyric Acid and Angiotensin-Converting Enzyme Inhibitors on Blood Pressure, Glucose Metabolism and Endothelial Function: A Double-blind Randomized Crossover Clinical Trial.	Becerra-Tomas N, Guasch-Ferre M, Quilez J, Merino J, Ferre R, Diaz-Lopez A, Bullo M, Hernandez-Alonso P, Palau-Galindo A, Salas-Salvado J.	Medicine (Baltimore)	10.1097/md.0000000000001807	2015
	Preservative effect of Chinese cabbage (Brassica rapa subsp. pekinensis) extract on their molecular docking, antioxidant and antimicrobial properties.	Rubab M, Chellia R, Saravanakumar K, Mandava S, Khan I, Tango CN, Hussain MS, Daliri EB, Kim SH, Ramakrishnan SR, Wang MH, Lee J, Kwon JH, Chandrashekar S, Oh DH.	PLoS One	10.1371/journal.pone.0203306	2018
	Controlled functional expression of the bacteriocins pediocin PA-1 and bactofencin A in Escherichia coli.	Mesa-Pereira B, O'Connor PM, Rea MC, Cotter PD, Hill C, Ross RP.	Sci Rep	10.1038/s41598-017-02868-w	2017
	Prebiotic potential of Agave angustifolia Haw fructans with different degrees of polymerization.	Velazquez-Martinez JR, Gonzalez-Cervantes RM, Hernandez-Gallegos MA, Mendiola RC, Aparicio AR, Ocampo ML.	Molecules	10.3390/molecules190812660	2014
Genetics	Long-read based de novo assembly of low-complexity metagenome samples results in finished genomes and reveals insights into strain diversity and an active phage system.	Somerville V, Lutz S, Schmid M, Frei D, Moser A, Irmler S, Frey JE, Ahrens CH.	BMC Microbiol	10.1186/s12866-019-1500-0	2019
	Protective effects of two Lactobacillus plantarum strains in hyperlipidemic mice.	Wang LX, Liu K, Gao DW, Hao JK.	World J Gastroenterol	10.3748/wjg.v19.i20.3150	2013
Phylogeny	Bifidobacterium animalis subsp. lactis ATCC 27673 is a genomically unique strain within its conserved subspecies.	Loquasto JR, Barrangou R, Dudley EG, Stahl B, Chen C, Roberts RF.	Appl Environ Microbiol	10.1128/aem.01777-13	2013
	Production, active staining and gas chromatography assay analysis of recombinant aminopeptidase P from Lactococcus lactis ssp. lactis DSM 20481.	Stressler T, Eisele T, Schlayer M, Fischer L.	AMB Express	10.1186/2191-0855-2-39	2012
	Design, construction, and in vivo augmentation of a complex gut microbiome.	Cheng AG, Ho PY, Aranda-Diaz A, Jain S, Yu FB, Meng X, Wang M, Iakiviak M, Nagashima K, Zhao A, Murugkar P, Patil A, Atabakhsh K, Weakley A, Yan J, Brumbaugh AR, Higginbottom S, Dimas A, Shiver AL, Deutschbauer A, Neff N, Sonnenburg JL, Huang KC, Fischbach MA.	Cell	10.1016/j.cell.2022.08.003	2022
	Effects of feeding of two potentially probiotic preparations from lactic acid bacteria on the performance and faecal microflora of broiler chickens.	Fajardo P, Pastrana L, Mendez J, Rodriguez I, Fucinos C, Guerra NP.	ScientificWorldJournal	10.1100/2012/562635	2012
Enzymology	Role of bifidobacteria in the hydrolysis of chlorogenic acid.	Raimondi S, Anighoro A, Quartieri A, Amaretti A, Tomas-Barberan FA, Rastelli G, Rossi M.	Microbiologyopen	10.1002/mbo3.219	2015
Metabolism	Strong synergy between a eukaryotic antimicrobial peptide and bacteriocins from lactic acid bacteria.	Luders T, Birkemo GA, Fimland G, Nissen-Meyer J, Nes IF.	Appl Environ Microbiol	10.1128/aem.69.3.1797-1799.2003	2003
	A Novel Glutamyl (Aspartyl)-Specific Aminopeptidase A from Lactobacillus delbrueckii with Promising Properties for Application.	Stressler T, Ewert J, Merz M, Funk J, Claassen W, Lutz-Wahl S, Schmidt H, Kuhn A, Fischer L.	PLoS One	10.1371/journal.pone.0152139	2016
Phenotype	Characterization of a wild, novel nisin a-producing Lactococcus strain with an L. lactis subsp. cremoris genotype and an L. lactis subsp. lactis phenotype, isolated from Greek raw milk.	Parapouli M, Delbes-Paus C, Kakouri A, Koukkou AI, Montel MC, Samelis J.	Appl Environ Microbiol	10.1128/aem.00436-13	2013
	Comparison of the complete genome sequences of Bifidobacterium animalis subsp. lactis DSM 10140 and Bl-04.	Barrangou R, Briczinski EP, Traeger LL, Loquasto JR, Richards M, Horvath P, Coute-Monvoisin AC, Leyer G, Rendulic S, Steele JL, Broadbent JR, Oberg T, Dudley EG, Schuster S, Romero DA, Roberts RF.	J Bacteriol	10.1128/jb.00155-09	2009
	Mutational analysis of residues in the helical region of the class IIa bacteriocin pediocin PA-1.	Haugen HS, Fimland G, Nissen-Meyer J.	Appl Environ Microbiol	10.1128/aem.02488-10	2011
Metabolism	In vitro kinetic analysis of fermentation of prebiotic inulin-type fructans by Bifidobacterium species reveals four different phenotypes.	Falony G, Lazidou K, Verschaeren A, Weckx S, Maes D, De Vuyst L.	Appl Environ Microbiol	10.1128/aem.01488-08	2009
Metabolism	Development of a double-crossover markerless gene deletion system in Bifidobacterium longum: functional analysis of the alpha-galactosidase gene for raffinose assimilation.	Hirayama Y, Sakanaka M, Fukuma H, Murayama H, Kano Y, Fukiya S, Yokota A.	Appl Environ Microbiol	10.1128/aem.00588-12	2012
	Structure-function analysis of immunity proteins of pediocin-like bacteriocins: C-terminal parts of immunity proteins are involved in specific recognition of cognate bacteriocins.	Johnsen L, Fimland G, Mantzilas D, Nissen-Meyer J.	Appl Environ Microbiol	10.1128/aem.70.5.2647-2652.2004	2004
Phylogeny	Rapid differentiation and in situ detection of 16 sourdough lactobacillus species by multiplex PCR.	Settanni L, van Sinderen D, Rossi J, Corsetti A.	Appl Environ Microbiol	10.1128/aem.71.6.3049-3059.2005	2005
Enzymology	Prophage-like elements in bifidobacteria: insights from genomics, transcription, integration, distribution, and phylogenetic analysis.	Ventura M, Lee JH, Canchaya C, Zink R, Leahy S, Moreno-Munoz JA, O'Connell-Motherway M, Higgins D, Fitzgerald GF, O'Sullivan DJ, van Sinderen D.	Appl Environ Microbiol	10.1128/aem.71.12.8692-8705.2005	2005
Genetics	Genome sequence analysis of potential probiotic strain Leuconostoc lactis EFEL005 isolated from kimchi.	Moon JS, Choi HS, Shin SY, Noh SJ, Jeon CO, Han NS	J Microbiol	10.1007/s12275-015-5090-8	2015
Genetics	Genome sequence of Leuconostoc argentinum KCTC 3773.	Nam SH, Choi SH, Kang A, Kim DW, Kim RN, Kim A, Park HS	J Bacteriol	10.1128/JB.01148-10	2010
Phylogeny	Characterization of Leuconostoc gasicomitatum sp. nov., associated with spoiled raw tomato-marinated broiler meat strips packaged under modified-atmosphere conditions.	Bjorkroth KJ, Geisen R, Schillinger U, Weiss N, De Vos P, Holzapfel WH, Korkeala HJ, Vandamme P.	Appl Environ Microbiol	10.1128/aem.66.9.3764-3772.2000	2000

References

#3310	Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 8581
#20215	Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 )
#20218	Verslyppe, B., De Smet, W., De Baets, B., De Vos, P., Dawyndt P.: StrainInfo introduces electronic passports for microorganisms.. Syst Appl Microbiol. 37: 42 - 50 2014 ( DOI 10.1016/j.syapm.2013.11.002 , PubMed 24321274 )
#38487	Collection of Institut Pasteur ; Curators of the CIP; CIP 103889
#54529	Culture Collection University of Gothenburg (CCUG) ; Curators of the CCUG; CCUG 38887
#66792	Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) .
#67770	Japan Collection of Microorganism (JCM) ; Curators of the JCM;
#68371	Automatically annotated from API 50CH acid .
#69479	João F Matias Rodrigues, Janko Tackmann,Gregor Rot, Thomas SB Schmidt, Lukas Malfertheiner, Mihai Danaila,Marija Dmitrijeva, Daniela Gaio, Nicolas Näpflin and Christian von Mering. University of Zurich.: MicrobeAtlas 1.0 beta .
#125438	Julia Koblitz, Lorenz Christian Reimer, Rüdiger Pukall, Jörg Overmann: Predicting bacterial phenotypic traits through improved machine learning using high-quality, curated datasets. 2024 ( DOI 10.1101/2024.08.12.607695 )
#125439	Philipp Münch, René Mreches, Martin Binder, Hüseyin Anil Gündüz, Xiao-Yin To, Alice McHardy: deepG: Deep Learning for Genome Sequence Data. R package version 0.3.1 .
#126262	A. Lissin, I. Schober, J. F. Witte, H. Lüken, A. Podstawka, J. Koblitz, B. Bunk, P. Dawyndt, P. Vandamme, P. de Vos, J. Overmann, L. C. Reimer: StrainInfo—the central database for linked microbial strain identifiers. ( DOI 10.1093/database/baaf059 )

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Leuconostoc lactis (DSM 8581, JCM 11052, CCUG 38887)

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