Leptospira santarosai (DSM 21524, ATCC 43286, 1342)

Name: Leptospira santarosai (DSM 21524, ATCC 43286, 1342)
Creator: BacDive
License: http://creativecommons.org/licenses/by/4.0/

BacDive ID 6801

Type strain

Strain Designation 1342, LT 821, Shermani

Culture col. no. DSM 21524 ATCC 43286 1342 LT 821 Shermani

NCBI tax ID(s) 28183

Special Collections DSMZ

Links

Leptospira santarosai 1342 is a prokaryote that was isolated from spiney rat kidney, Proechimys semispinosus.

genome sequence 16S sequence

Name and taxonomic classification

SI-ID 41756

ATCC 43286

@ref 20215

Last LPSN update 2025-12-16 09:48:25

Domain Pseudomonadati

Phylum Spirochaetota

Class Spirochaetia

Order Leptospirales

Family Leptospiraceae

Genus Leptospira

Species Leptospira santarosai

Full scientific name Leptospira santarosai Yasuda et al. 1987

BacDive ID	Other strains from **Leptospira santarosai** (53)	Type strain
173551	L. santarosai LEP1215, 1342 K, CRBIP6.1215 (type strain)
173556	L. santarosai LEP1274, MW 10, CRBIP6.1274 (type strain)
173552	L. santarosai LEP1241, Alice, CRBIP6.1241
173553	L. santarosai LEP1261, NN-1, CRBIP6.1261
173554	L. santarosai LEP1266, 735 U, CRBIP6.1266
173555	L. santarosai LEP1269, CZ 320, CRBIP6.1269
173557	L. santarosai LEP1277, 24, CRBIP6.1277
173558	L. santarosai LEP1280, MR 12, CRBIP6.1280
173559	L. santarosai LEP 1288, Bovino 131, CRBIP6.1288
173560	L. santarosai LEP 1289, An 776, CRBIP6.1289
173561	L. santarosai LEP1290, CT 63, CRBIP6.1290
173562	L. santarosai LEP 1291, Bovino 131, CRBIP6.1291
173563	L. santarosai LEP 1297, Aa3, CRBIP6.1297
173564	L. santarosai LEP1301, M 13, CRBIP6.1301
173565	L. santarosai LEP1303, MW12, CRBIP6.1303
173566	L. santarosai LEP 1320, Rr 5, CRBIP6.1320
173567	L. santarosai LEP1321, MMD3, CRBIP6.1321
173568	L. santarosai LEP1323, LT 117, CRBIP6.1323
173569	L. santarosai LEP1324, M 3, CRBIP6.1324
173570	L. santarosai LEP1328, 1019, CRBIP6.1328
173571	L. santarosai LEP1331, CT 63, CRBIP6.1331
173572	L. santarosai LEP1332, 24, CRBIP6.1332
173573	L. santarosai LEP1333, M3, CRBIP6.1333
173574	L. santarosai LEP1338, CZ 299, CRBIP6.1338
173575	L. santarosai LEP1349, 45-74, CRBIP6.1349
173576	L. santarosai LEP1352, CZ 390, CRBIP6.1352
173577	L. santarosai LEP1358, M 6, CRBIP6.1358
173578	L. santarosai LEP1363, 637 K, CRBIP6.1363
173579	L. santarosai LEP1367, LT 81, CRBIP6.1367
173580	L. santarosai LEP1368, CRBIP6.1368, LSU 1013
173581	L. santarosai LEP1369, 316, CRBIP6.1369
173582	L. santarosai LEP1371, CRBIP6.1371, LSU 1013
173583	L. santarosai LEP1374, HS 622, CRBIP6.1374
173584	L. santarosai LEP 1376, Bov. G., CRBIP6.1376
173585	L. santarosai LEP1384, LT 839, CRBIP6.1384
173586	L. santarosai LEP1385, TRVL 109873, CRBIP6.1385
173587	L. santarosai LEP1386, 1473 K, CRBIP6.1386
173588	L. santarosai LEP1387, LT 79, CRBIP6.1387
173589	L. santarosai LEP1393, Bravo, CRBIP6.1393
173590	L. santarosai LEP1396, LT 82, CRBIP6.1396
173591	L. santarosai LEP1408, LT 924, CRBIP6.1408
173592	L. santarosai LEP1411, TRVL 34056 (LT 1098), CRBIP6.1411
173593	L. santarosai LEP1416, HS 616, CRBIP6.1416
173594	L. santarosai LEP1421, TVRL 3214, CRBIP6.1421
173595	L. santarosai LEP1428, 1413 U, CRBIP6.1428
173596	L. santarosai LEP1440, CZ 188, CRBIP6.1440
173597	L. santarosai LEP1443, Cl 40, CRBIP6.1443
173598	L. santarosai LEP1450, 1537 U, CRBIP6.1450
173599	L. santarosai LEP1453, 1413 U, CRBIP6.1453
173600	L. santarosai LEP1454, TRVL 112499, CRBIP6.1454
173601	L. santarosai LEP1472, CZ 285, CRBIP6.1472
173602	L. santarosai LEP1478, 1913 K, CRBIP6.1478
173603	L. santarosai LEP1484, MW2, CRBIP6.1484

Morphology

Cell morphology

@ref	Gram stain	Confidence
125439	negative	99.9
125438	negative	92.257

Culture and growth conditions

Physiology and metabolism

Oxygen tolerance

@ref	Oxygen tolerance	Confidence
125439	obligate aerobe	94.9

Spore formation

@ref	Spore formation	Confidence
125439		99.7

Isolation, sampling and environmental information

Isolation source categories

Cat1	Cat2	Cat3
#Host	#Mammals	#Rodentia (Other)
#Host Body-Site	#Urogenital tract	#Kidney

Isolation

@ref	Sample type	Host species	Country	Country ISO 3 Code	Continent
15760	spiney rat kidney, Proechimys semispinosus	Proechimys semispinosus	Panama	PAN	Middle and South America

Interaction and safety

Risk assessment

@ref	Biosafety level	Biosafety level comment
15760	2	Risk group (German classification) According to TRBA 466

Sequence information

Genome sequences

@ref	Description	Assembly level	INSDC accession	BV-BRC accession	IMG accession	NCBI tax ID	Score
66792	ASM31317v2 assembly for Leptospira santarosai serovar Shermani str. LT 821	complete	GCA_000313175	758847.45	2537562171	758847	88.47
66792	Leptospira santarosai serovar Shermani str. LT 821	contig		758847.3		758847	58.6

16S sequences

@ref	Description	Accession	Length	Database	NCBI tax ID
15760	Leptospira santarosai serovar Shermani strain LT 821 16S ribosomal RNA gene, partial sequence	AY631883	1431		758847

GC content

@ref	GC-content (mol%)	Method
15760	40.7	high performance liquid chromatography (HPLC)

Genome-based predictions

Predictions

Predictions from Deep Learning for Genome Sequence Data. R package version 0.3.1 based on: Leptospira santarosai serovar Shermani str. LT 821
PATRIC: 758847.3

@ref	Trait	Model	Prediction	Confidence in %	In training data
125439	spore_formation	BacteriaNetⓘ	no	99.70	no
125439	motility	BacteriaNetⓘ	no	71.30	no
125439	gram_stain	BacteriaNetⓘ	negative	99.90	no
125439	oxygen_tolerance	BacteriaNetⓘ	obligate aerobe	94.90	no

Predictions from bacterial phenotypic traits through improved machine learning using high-quality, curated datasets based on: Leptospira santarosai serovar Shermani str. LT 821 LT 821
NCBI: GCA_000313175.2

@ref	Trait	Model	Prediction	Confidence in %	In training data
125438	gram-positive	gram-positiveⓘ	no	92.26	no
125438	anaerobic	anaerobicⓘ	no	80.89	no
125438	aerobic	aerobicⓘ	yes	64.69	no
125438	spore-forming	spore-formingⓘ	no	79.98	no
125438	thermophilic	thermophileⓘ	no	87.07	no
125438	flagellated	motile2+ⓘ	yes	51.71	no

Literature

Topic	Title	Authors	Journal	DOI	Year
Metabolism	Leptospira santorosai Serovar Shermani detergent extract induces an increase in fibronectin production through a Toll-like receptor 2-mediated pathway.	Tian YC, Hung CC, Li YJ, Chen YC, Chang MY, Yen TH, Hsu HH, Wu MS, Phillips A, Yang CW.	Infect Immun	10.1128/iai.01287-09	2011
Pathogenicity	Factors associated with severity and mortality in patients with confirmed leptospirosis at a regional hospital in northern Taiwan.	Wang HK, Lee MH, Chen YC, Hsueh PR, Chang SC	J Microbiol Immunol Infect	10.1016/j.jmii.2018.05.005	2018
Phylogeny	Plurality of Leptospira strains on slaughtered animals suggest a broader concept of adaptability of leptospires to cattle.	Pinto PS, Pestana C, Medeiros MA, Lilenbaum W	Acta Trop	10.1016/j.actatropica.2017.04.032	2017
Metabolism	Leptospiral outer membrane protein LipL32 induces inflammation and kidney injury in zebrafish larvae.	Chang MY, Cheng YC, Hsu SH, Ma TL, Chou LF, Hsu HH, Tian YC, Chen YC, Sun YJ, Hung CC, Pan RL, Yang CW	Sci Rep	10.1038/srep27838	2016
	Potential impact on kidney infection: a whole-genome analysis of Leptospira santarosai serovar Shermani.	Chou LF, Chen TW, Ko YC, Pan MJ, Tian YC, Chiu CH, Tang P, Hung CC, Yang CW	Emerg Microbes Infect	10.1038/emi.2014.78	2014
Metabolism	LipL41, a hemin binding protein from Leptospira santarosai serovar Shermani.	Lin MH, Chang YC, Hsiao CD, Huang SH, Wang MS, Ko YC, Yang CW, Sun YJ	PLoS One	10.1371/journal.pone.0083246	2013
Genetics	Sequence of Leptospira santarosai serovar Shermani genome and prediction of virulence-associated genes.	Chou LF, Chen YT, Lu CW, Ko YC, Tang CY, Pan MJ, Tian YC, Chiu CH, Hung CC, Yang CW	Gene	10.1016/j.gene.2012.09.074	2012
Pathogenicity	Demographic and clinical features of leptospirosis: three-year experience in central Taiwan.	Lin PC, Chi CY, Ho MW, Chen CM, Ho CM, Wang JH	J Microbiol Immunol Infect		2008
Pathogenicity	Leptospirosis in Taiwan--an underestimated infectious disease.	Yang CW	Chang Gung Med J	3002/300202	2007
Metabolism	Leptospiral outer membrane protein induces extracellular matrix accumulation through a TGF-beta1/Smad-dependent pathway.	Tian YC, Chen YC, Hung CC, Chang CT, Wu MS, Phillips AO, Yang CW	J Am Soc Nephrol	10.1681/ASN.2006020159	2006
Pathogenicity	Upregulation of chemokine CXCL1/KC by leptospiral membrane lipoprotein preparation in renal tubule epithelial cells.	Hung CC, Chang CT, Chen KH, Tian YC, Wu MS, Pan MJ, Vandewalle A, Yang CW	Kidney Int	10.1038/sj.ki.5000362	2006
Pathogenicity	Toll-like receptor 2 mediates early inflammation by leptospiral outer membrane proteins in proximal tubule cells.	Yang CW, Hung CC, Wu MS, Tian YC, Chang CT, Pan MJ, Vandewalle A	Kidney Int	10.1038/sj.ki.5000119	2006
Metabolism	Leptospiral membrane proteins stimulate pro-inflammatory chemokines secretion by renal tubule epithelial cells through toll-like receptor 2 and p38 mitogen activated protein kinase.	Hung CC, Chang CT, Tian YC, Wu MS, Yu CC, Pan MJ, Vandewalle A, Yang CW	Nephrol Dial Transplant	10.1093/ndt/gfi316	2005
Metabolism	Omp52 is a growth-phase-regulated outer membrane protein of Leptospira santarosai serovar Shermani.	Hsieh WJ, Chang YF, Chen CS, Pan MJ	FEMS Microbiol Lett	10.1016/j.femsle.2004.12.021	2005

References

#15760	Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 21524
#20215	Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 )
#66792	Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) .
#125438	Julia Koblitz, Lorenz Christian Reimer, Rüdiger Pukall, Jörg Overmann: Predicting bacterial phenotypic traits through improved machine learning using high-quality, curated datasets. 2024 ( DOI 10.1101/2024.08.12.607695 )
#125439	Philipp Münch, René Mreches, Martin Binder, Hüseyin Anil Gündüz, Xiao-Yin To, Alice McHardy: deepG: Deep Learning for Genome Sequence Data. R package version 0.3.1 .
#126262	A. Lissin, I. Schober, J. F. Witte, H. Lüken, A. Podstawka, J. Koblitz, B. Bunk, P. Dawyndt, P. Vandamme, P. de Vos, J. Overmann, L. C. Reimer: StrainInfo—the central database for linked microbial strain identifiers. ( DOI 10.1093/database/baaf059 )

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Leptospira santarosai (DSM 21524, ATCC 43286, 1342)

Name and taxonomic classification

Morphology

Cell morphology

Culture and growth conditions

Physiology and metabolism

Oxygen tolerance

Spore formation

Isolation, sampling and environmental information

Isolation source categories

Isolation

Interaction and safety

Risk assessment

Sequence information

Genome sequences

Genome browser: GCA_000313175

16S sequences

GC content

Genome-based predictions

Predictions

Literature

Literature

References

BacDive

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