Legionella pneumophila subsp. pneumophila R52 is a microaerophile, Gram-negative, rod-shaped bacterium that was isolated from showerhead.
Gram-negative rod-shaped microaerophile genome sequence Bacteria| @ref 20215 |
|
Last LPSN update
2026-05-29 08:26:29 |
| Domain Bacteria |
| Phylum Pseudomonadota |
| Class Gammaproteobacteria |
| Order Legionellales |
| Family Legionellaceae |
| Genus Legionella |
| Species Legionella pneumophila subsp. pneumophila |
| Full scientific name Legionella pneumophila subsp. pneumophila (Brenner et al. 1979) Brenner et al. 1989 |
| @ref | Name | Growth | Medium link | Composition | |
|---|---|---|---|---|---|
| 17928 | BCYE-AGAR (DSMZ Medium 585) | Medium recipe at MediaDive  | Name: BCYE AGAR (DSMZ Medium 585) Composition: OXOID Legionella CYE-Agar base | ||
| 36893 | MEDIUM 23 - for Afipia and Legionella | Distilled water make up to (1000.000 ml);Legionella agar (37.000 g);Legionella - enrichment mixture (10.000 ml) | |||
| 121902 | CIP Medium 23 | Medium recipe at CIP |
| 17928 | Oxygen tolerancemicroaerophile |
| @ref | Value | Activity | Ec | |
|---|---|---|---|---|
| 68382 | acid phosphatase | + | 3.1.3.2 | from API zym |
| 68382 | alkaline phosphatase | + | 3.1.3.1 | from API zym |
| 68382 | alpha-chymotrypsin | - | 3.4.21.1 | from API zym |
| 68382 | alpha-fucosidase | - | 3.2.1.51 | from API zym |
| 68382 | alpha-galactosidase | - | 3.2.1.22 | from API zym |
| 68382 | alpha-glucosidase | - | 3.2.1.20 | from API zym |
| 68382 | alpha-mannosidase | - | 3.2.1.24 | from API zym |
| 68382 | beta-galactosidase | - | 3.2.1.23 | from API zym |
| 68382 | beta-glucosidase | - | 3.2.1.21 | from API zym |
| 68382 | beta-glucuronidase | - | 3.2.1.31 | from API zym |
| 17928 | catalase | + | 1.11.1.6 | |
| 121902 | catalase | + | 1.11.1.6 | |
| 68382 | cystine arylamidase | - | 3.4.11.3 | from API zym |
| 17928 | cytochrome-c oxidase | + | 1.9.3.1 | |
| 68382 | esterase (C 4) | + | from API zym | |
| 68382 | esterase lipase (C 8) | - | from API zym | |
| 68382 | leucine arylamidase | + | 3.4.11.1 | from API zym |
| 68382 | lipase (C 14) | - | from API zym | |
| 68382 | N-acetyl-beta-glucosaminidase | - | 3.2.1.52 | from API zym |
| 68382 | naphthol-AS-BI-phosphohydrolase | + | from API zym | |
| 121902 | oxidase | - | ||
| 68382 | trypsin | - | 3.4.21.4 | from API zym |
| 121902 | urease | - | 3.5.1.5 | |
| 68382 | valine arylamidase | + | from API zym |
| @ref | Description | Assembly level | INSDC accession | BV-BRC accession | IMG accession | NCBI tax ID | Score | |
|---|---|---|---|---|---|---|---|---|
| 66792 | 45076_F02 assembly for Legionella pneumophila NCTC11984 | contig | GCA_900461605   | 446.734  | 2907362625  | 446 | 78.39 | |
| 66792 | ASM158230v1 assembly for Legionella pneumophila ATCC 33823 | scaffold | GCA_001582305 | 446.152 | 446 | 69.16 | | |
| 66792 | ATCC_33823 assembly for Legionella pneumophila subsp. pneumophila ATCC 33823 | scaffold | GCA_000586235 | 91891.31 | 2660238565 | 91891 | 65.19 | |
| Topic | Title | Authors | Journal | DOI | Year | |
|---|---|---|---|---|---|---|
| A novel hybridization capture method for direct whole genome sequencing of clinical specimens to inform Legionnaires' disease investigations. | Weeber P, Singh N, Lapierre P, Mingle L, Wroblewski D, Nazarian EJ, Haas W, Weiss D, Musser KA. | J Clin Microbiol | 10.1128/jcm.01305-23 | 2024 | | |
| Development of a Multiplex-PCR Serotyping Assay for Characterizing Legionella pneumophila Serogroups Based on the Diversity of Lipopolysaccharide Biosynthetic Loci. | Nakaue R, Qin T, Morita M, Ren H, Chang B, Murai M, Amemura-Maekawa J, Ohnishi M. | J Clin Microbiol | 10.1128/jcm.00157-21 | 2021 | | |
| Use of Fourier-Transform Infrared Spectroscopy With IR Biotyper® System for Legionella pneumophila Serogroups Identification. | Pascale MR, Bisognin F, Mazzotta M, Girolamini L, Marino F, Dal Monte P, Cordovana M, Scaturro M, Ricci ML, Cristino S. | Front Microbiol | 10.3389/fmicb.2022.866426 | 2022 | | |
| Phylogeny | Approach to determine the diversity of Legionella species by nested PCR-DGGE in aquatic environments. | Huang WC, Tsai HC, Tao CW, Chen JS, Shih YJ, Kao PM, Huang TY, Hsu BM. | PLoS One | 10.1371/journal.pone.0170992 | 2017 | |
| Pathogenicity | Bacterial Long-Range Warfare: Aerial Killing of Legionella pneumophila by Pseudomonas fluorescens. | Corre MH, Mercier A, Bouteiller M, Khalil A, Ginevra C, Depayras S, Dupont C, Rouxel M, Gallique M, Grac L, Jarraud S, Giron D, Merieau A, Berjeaud JM, Verdon J. | Microbiol Spectr | 10.1128/spectrum.00404-21 | 2021 | |
| Human macrophages utilize a wide range of pathogen recognition receptors to recognize Legionella pneumophila, including Toll-Like Receptor 4 engaging Legionella lipopolysaccharide and the Toll-like Receptor 3 nucleic-acid sensor. | Grigoryeva LS, Cianciotto NP. | PLoS Pathog | 10.1371/journal.ppat.1009781 | 2021 | | |
| Enzymology | Assessment of Legionella pneumophila in recreational spring water with quantitative PCR (Taqman) assay. | Shen SM, Chou MY, Hsu BM, Ji WT, Hsu TK, Tsai HF, Huang YL, Chiu YC, Kao ES, Kao PM, Fan CW. | Pathog Glob Health | 10.1179/2047773215y.0000000023 | 2015 | |
| Enzymology | Effect of Common Drinking Water Disinfectants, Chlorine and Heat, on Free Legionella and Amoebae-Associated Legionella. | Cervero-Arago S, Rodriguez-Martinez S, Puertas-Bennasar A, Araujo RM. | PLoS One | 10.1371/journal.pone.0134726 | 2015 | |
| Phylogeny | Development of a DNA microarray method for detection and identification of all 15 distinct O-antigen forms of Legionella pneumophila. | Cao B, Yao F, Liu X, Feng L, Wang L. | Appl Environ Microbiol | 10.1128/aem.01957-13 | 2013 | |
| Occurrence and Control of Legionella in Recycled Water Systems. | Jjemba PK, Johnson W, Bukhari Z, LeChevallier MW. | Pathogens | 10.3390/pathogens4030470 | 2015 | | |
| Pathogenicity | Susceptibility of Legionella strains to the chlorinated biocide, monochloramine. | Jakubek D, Guillaume C, Binet M, Leblon G, DuBow M, Le Brun M. | Microbes Environ | 10.1264/jsme2.me12205 | 2013 | |
| Phylogeny | The N-acylneuraminate cytidyltransferase gene, neuA, is heterogenous in Legionella pneumophila strains but can be used as a marker for epidemiological typing in the consensus sequence-based typing scheme. | Farhat C, Mentasti M, Jacobs E, Fry NK, Luck C. | J Clin Microbiol | 10.1128/jcm.00687-11 | 2011 | |
| Opportunistic Pathogens in Drinking Water Distribution Systems-A Review. | LeChevallier MW, Prosser T, Stevens M. | Microorganisms | 10.3390/microorganisms12050916 | 2024 | | |
| Enzymology | Surveillance of parasitic Legionella in surface waters by using immunomagnetic separation and amoebae enrichment. | Hsu TK, Wu SF, Hsu BM, Kao PM, Tao CW, Shen SM, Ji WT, Huang WC, Fan CW. | Pathog Glob Health | 10.1179/2047773215y.0000000034 | 2015 | |
| Enzymology | Accurate, rapid and low-cost diagnosis of Mycoplasma pneumoniae via fast narrow-thermal-cycling denaturation bubble-mediated strand exchange amplification. | Yang C, Li Y, Deng J, Li M, Ma C, Shi C. | Anal Bioanal Chem | 10.1007/s00216-020-02977-y | 2020 | |
| Phylogeny | Two-step scheme for rapid identification and differentiation of Legionella pneumophila and non-Legionella pneumophila species. | Zhan XY, Li LQ, Hu CH, Zhu QY. | J Clin Microbiol | 10.1128/jcm.01778-09 | 2010 | |
| Legionellosis and Recent Advances in Technologies for Legionella Control in Premise Plumbing Systems: A Review. | Carlson KM, Boczek LA, Chae S, Ryu H. | Water (Basel) | 10.3390/w12030676 | 2020 | | |
| Enzymology | Purification and characterization of a UDP-glucosyltransferase produced by Legionella pneumophila. | Belyi I, Popoff MR, Cianciotto NP. | Infect Immun | 10.1128/iai.71.1.181-186.2003 | 2003 | |
| Metabolism | Lgt: a family of cytotoxic glucosyltransferases produced by Legionella pneumophila. | Belyi Y, Tabakova I, Stahl M, Aktories K. | J Bacteriol | 10.1128/jb.01798-07 | 2008 | |
| Molecular evolution of the dotA gene in Legionella pneumophila. | Ko KS, Hong SK, Lee HK, Park MY, Kook YH. | J Bacteriol | 10.1128/jb.185.21.6269-6277.2003 | 2003 | | |
| Phylogeny | Population genetic structure of Legionella pneumophila inferred from RNA polymerase gene (rpoB) and DotA gene (dotA) sequences. | Ko KS, Lee HK, Park MY, Park MS, Lee KH, Woo SY, Yun YJ, Kook YH. | J Bacteriol | 10.1128/jb.184.8.2123-2130.2002 | 2002 | |
| Enzymology | Quantitative real-time Legionella PCR for environmental water samples: data interpretation. | Joly P, Falconnet PA, Andre J, Weill N, Reyrolle M, Vandenesch F, Maurin M, Etienne J, Jarraud S. | Appl Environ Microbiol | 10.1128/aem.72.4.2801-2808.2006 | 2006 | |
| Pathogenicity | In vitro activity of macrolides against intracellular Legionella pneumophila. | Segreti J, Meyer P, Kapell K. | Diagn Microbiol Infect Dis | 10.1016/s0732-8893(96)00097-1 | 1996 | |
| Phylogeny | Identification of legionella species by use of an oligonucleotide array. | Su HP, Tung SK, Tseng LR, Tsai WC, Chung TC, Chang TC. | J Clin Microbiol | 10.1128/jcm.02225-08 | 2009 | |
| Characterization of a tandem repeat polymorphism in Legionella pneumophila and its use for genotyping. | Pourcel C, Vidgop Y, Ramisse F, Vergnaud G, Tram C. | J Clin Microbiol | 10.1128/jcm.41.5.1819-1826.2003 | 2003 | | |
| Metabolism | Targeting species-specific low-affinity 16S rRNA binding sites by using peptide nucleic acids for detection of Legionellae in biofilms. | Wilks SA, Keevil CW. | Appl Environ Microbiol | 10.1128/aem.02918-05 | 2006 | |
| Enzymology | Detection of legionellae in hospital water samples by quantitative real-time LightCycler PCR. | Wellinghausen N, Frost C, Marre R. | Appl Environ Microbiol | 10.1128/aem.67.9.3985-3993.2001 | 2001 | |
| Metabolism | Isolation of a gene encoding a novel spectinomycin phosphotransferase from Legionella pneumophila. | Suter TM, Viswanathan VK, Cianciotto NP. | Antimicrob Agents Chemother | 10.1128/aac.41.6.1385 | 1997 | |
| Enzymology | Presence and persistence of Legionella spp. in groundwater. | Costa J, Tiago I, da Costa MS, Verissimo A. | Appl Environ Microbiol | 10.1128/aem.71.2.663-671.2005 | 2005 | |
| Phylogeny | Genetic and phenotypic differences between Legionella pneumophila strains. | Samrakandi MM, Cirillo SL, Ridenour DA, Bermudez LE, Cirillo JD. | J Clin Microbiol | 10.1128/jcm.40.4.1352-1362.2002 | 2002 | |
| Metabolism | Discovery of a nonclassical siderophore, legiobactin, produced by strains of Legionella pneumophila. | Liles MR, Scheel TA, Cianciotto NP. | J Bacteriol | 10.1128/jb.182.3.749-757.2000 | 2000 | |
| Identification of Legionella pneumophila rcp, a pagP-like gene that confers resistance to cationic antimicrobial peptides and promotes intracellular infection. | Robey M, O'Connell W, Cianciotto NP. | Infect Immun | 10.1128/iai.69.7.4276-4286.2001 | 2001 | | |
| Enzymology | Isolation and characterization of a seventh serogroup of Legionella pneumophila. | Bibb WF, Arnow PM, Dellinger DL, Perryman SR. | J Clin Microbiol | 10.1128/jcm.17.2.346-348.1983 | 1983 | |
| Enzymology | Development of conventional and real-time PCR assays for detection of Legionella DNA in respiratory specimens. | Rantakokko-Jalava K, Jalava J. | J Clin Microbiol | 10.1128/jcm.39.8.2904-2910.2001 | 2001 | |
| Enzymology | Application of RNA polymerase beta-subunit gene (rpoB) sequences for the molecular differentiation of Legionella species. | Ko KS, Lee HK, Park MY, Lee KH, Yun YJ, Woo SY, Miyamoto H, Kook YH. | J Clin Microbiol | 10.1128/jcm.40.7.2653-2658.2002 | 2002 | |
| Enzymology | Enzyme-linked immunoassay for detection of PCR-amplified DNA of legionellae in bronchoalveolar fluid. | Jonas D, Rosenbaum A, Weyrich S, Bhakdi S. | J Clin Microbiol | 10.1128/jcm.33.5.1247-1252.1995 | 1995 | |
| Phase-variable expression of lipopolysaccharide contributes to the virulence of legionella pneumophila. | Luneberg E, Zahringer U, Knirel YA, Steinmann D, Hartmann M, Steinmetz I, Rohde M, Kohl J, Frosch M. | J Exp Med | 10.1084/jem.188.1.49 | 1998 | | |
| Detection of Legionella spp. in bronchoalveolar lavage fluids by DNA amplification. | Jaulhac B, Nowicki M, Bornstein N, Meunier O, Prevost G, Piemont Y, Fleurette J, Monteil H. | J Clin Microbiol | 10.1128/jcm.30.4.920-924.1992 | 1992 | | |
| Metabolism | An iron- and fur-repressed Legionella pneumophila gene that promotes intracellular infection and encodes a protein with similarity to the Escherichia coli aerobactin synthetases. | Hickey EK, Cianciotto NP. | Infect Immun | 10.1128/iai.65.1.133-143.1997 | 1997 | |
| Identification of mip-like genes in the genus Legionella. | Cianciotto NP, Bangsborg JM, Eisenstein BI, Engleberg NC. | Infect Immun | 10.1128/iai.58.9.2912-2918.1990 | 1990 | | |
| Phylogeny | Characterization of members of the Legionellaceae family by automated ribotyping. | Cordevant C, Tang JS, Cleland D, Lange M. | J Clin Microbiol | 10.1128/jcm.41.1.34-43.2003 | 2003 | |
| Phylogeny | Hydroxy-fatty acid profiles of Legionella species: diagnostic usefulness assessed by principal component analysis. | Jantzen E, Sonesson A, Tangen T, Eng J. | J Clin Microbiol | 10.1128/jcm.31.6.1413-1419.1993 | 1993 | |
| Monoclonal antibodies to Legionella Mip proteins recognize genus- and species-specific epitopes. | Helbig JH, Ludwig B, Luck PC, Groh A, Witzleb W, Hacker J. | Clin Diagn Lab Immunol | 10.1128/cdli.2.2.160-165.1995 | 1995 | | |
| Genus-specific epitope on the 60-kilodalton Legionella heat shock protein recognized by a monoclonal antibody. | Steinmetz I, Rheinheimer C, Hubner I, Bitter-Suermann D. | J Clin Microbiol | 10.1128/jcm.29.2.346-354.1991 | 1991 | | |
| Phylogeny | Identification and DNA fingerprinting of Legionella strains by randomly amplified polymorphic DNA analysis. | Bansal NS, McDonell F. | J Clin Microbiol | 10.1128/jcm.35.9.2310-2314.1997 | 1997 | |
| Phylogeny | Usefulness of fatty acid composition for differentiation of Legionella species. | Diogo A, Verissimo A, Nobre MF, da Costa MS. | J Clin Microbiol | 10.1128/jcm.37.7.2248-2254.1999 | 1999 | |
| Detection of flagella in 278 Legionella strains by latex reagent sensitized with antiflagellum immunoglobulins. | Bornstein N, Marmet D, Dumaine MH, Surgot M, Fleurette J. | J Clin Microbiol | 10.1128/jcm.29.5.953-956.1991 | 1991 | | |
| Phylogeny | Sequence-based classification scheme for the genus Legionella targeting the mip gene. | Ratcliff RM, Lanser JA, Manning PA, Heuzenroeder MW. | J Clin Microbiol | 10.1128/jcm.36.6.1560-1567.1998 | 1998 | |
| COVID-19 pandemic lesson learned- critical parameters and research needs for UVC inactivation of viral aerosols. | Abkar L, Zimmermann K, Dixit F, Kheyrandish A, Mohseni M. | J Hazard Mater Adv | 10.1016/j.hazadv.2022.100183 | 2022 | | |
| Metabolism | Photocatalytic disinfection using titanium dioxide: spectrum and mechanism of antimicrobial activity. | Foster HA, Ditta IB, Varghese S, Steele A. | Appl Microbiol Biotechnol | 10.1007/s00253-011-3213-7 | 2011 | |
| Validation of MICA Legionella for Enumeration of Legionella pneumophila in Sanitary Waters and Cooling Tower Waters: AOAC Performance Tested MethodSM 032201. | Passot F, Peslier S, Benzinger MJ, Blackburn J, Thompson W, Bastin B, Dumont A, Dukan S. | J AOAC Int | 10.1093/jaoacint/qsac150 | 2023 | | |
| Intergenic 16S rRNA gene (rDNA)-23S rDNA sequence length polymorphisms in members of the family Legionellaceae. | Hookey JV, Birtles RJ, Saunders NA. | J Clin Microbiol | 10.1128/jcm.33.9.2377-2381.1995 | 1995 | | |
| Metabolism | Development of the BIOLOG substrate utilization system for identification of Legionella spp. | Mauchline WS, Keevil CW. | Appl Environ Microbiol | 10.1128/aem.57.11.3345-3349.1991 | 1991 | |
How to citeIf you want to cite this particular strain cite the following doi:
https://doi.org/10.13145/bacdive6782.20260601.11
When using BacDive for research please cite the following paper
BacDive in 2025: the core database for prokaryotic strain data
License