Legionella pneumophila subsp. pneumophila R51 is a microaerophile, Gram-negative, rod-shaped bacterium that was isolated from human lung biopsy.
Gram-negative rod-shaped microaerophile genome sequence 16S sequence Bacteria| @ref 20215 |
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Last LPSN update
2026-05-29 08:26:28 |
| Domain Bacteria |
| Phylum Pseudomonadota |
| Class Gammaproteobacteria |
| Order Legionellales |
| Family Legionellaceae |
| Genus Legionella |
| Species Legionella pneumophila subsp. pneumophila |
| Full scientific name Legionella pneumophila subsp. pneumophila (Brenner et al. 1979) Brenner et al. 1989 |
| @ref | Name | Growth | Medium link | Composition | |
|---|---|---|---|---|---|
| 17927 | BCYE-AGAR (DSMZ Medium 585) | Medium recipe at MediaDive  | Name: BCYE AGAR (DSMZ Medium 585) Composition: OXOID Legionella CYE-Agar base | ||
| 38479 | MEDIUM 23 - for Afipia and Legionella | Distilled water make up to (1000.000 ml);Legionella agar (37.000 g);Legionella - enrichment mixture (10.000 ml) | |||
| 121912 | CIP Medium 23 | Medium recipe at CIP |
| @ref | Value | Activity | Ec | |
|---|---|---|---|---|
| 68382 | acid phosphatase | + | 3.1.3.2 | from API zym |
| 68382 | alkaline phosphatase | + | 3.1.3.1 | from API zym |
| 68382 | alpha-chymotrypsin | - | 3.4.21.1 | from API zym |
| 68382 | alpha-fucosidase | - | 3.2.1.51 | from API zym |
| 68382 | alpha-galactosidase | - | 3.2.1.22 | from API zym |
| 68382 | alpha-glucosidase | - | 3.2.1.20 | from API zym |
| 68382 | alpha-mannosidase | - | 3.2.1.24 | from API zym |
| 68382 | beta-galactosidase | - | 3.2.1.23 | from API zym |
| 68382 | beta-glucosidase | - | 3.2.1.21 | from API zym |
| 68382 | beta-glucuronidase | - | 3.2.1.31 | from API zym |
| 17927 | catalase | + | 1.11.1.6 | |
| 121912 | catalase | + | 1.11.1.6 | |
| 68382 | cystine arylamidase | + | 3.4.11.3 | from API zym |
| 17927 | cytochrome-c oxidase | + | 1.9.3.1 | |
| 68382 | esterase (C 4) | + | from API zym | |
| 68382 | esterase lipase (C 8) | + | from API zym | |
| 68382 | leucine arylamidase | + | 3.4.11.1 | from API zym |
| 68382 | lipase (C 14) | - | from API zym | |
| 68382 | N-acetyl-beta-glucosaminidase | - | 3.2.1.52 | from API zym |
| 68382 | naphthol-AS-BI-phosphohydrolase | + | from API zym | |
| 121912 | oxidase | + | ||
| 68382 | trypsin | - | 3.4.21.4 | from API zym |
| 68382 | valine arylamidase | + | from API zym |
| @ref | Description | Assembly level | INSDC accession | BV-BRC accession | IMG accession | NCBI tax ID | Score | |
|---|---|---|---|---|---|---|---|---|
| 66792 | ATCC_33215 assembly for Legionella pneumophila subsp. pneumophila ATCC 33215 | scaffold | GCA_000586295   | 933085.3  | 2667527927  | 933085 | 65.71 | |
| Topic | Title | Authors | Journal | DOI | Year | |
|---|---|---|---|---|---|---|
| Genetics | Genotypic and phenotypic profiling of 127 Legionella pneumophila strains: Insights into regional spread. | Colautti A, Civilini M, Bortolomeazzi R, Franchi M, Felice A, De Martin S, Iacumin L. | PLoS One | 10.1371/journal.pone.0307646 | 2024 | |
| Terpinen-4-ol, the Main Bioactive Component of Tea Tree Oil, as an Innovative Antimicrobial Agent against Legionella pneumophila. | Mondello F, Fontana S, Scaturro M, Girolamo A, Colone M, Stringaro A, Vito MD, Ricci ML. | Pathogens | 10.3390/pathogens11060682 | 2022 | | |
| Development of a PCR Assay for the Detection of Legionella micdadei in the Environment. | Belanger WN, Bastien M, Berube E, Gagnon M, Sahnoun YG, Dancause V, Boissinot K, Lalancette C, Riel-Roberge C, Jacob-Wagner M, Trottier S, Biot-Pelletier D, Ruest A, Tetreault I, Theriault M, Isabel S. | Infect Dis Rep | 10.3390/idr17050131 | 2025 | | |
| Development of a Multiplex-PCR Serotyping Assay for Characterizing Legionella pneumophila Serogroups Based on the Diversity of Lipopolysaccharide Biosynthetic Loci. | Nakaue R, Qin T, Morita M, Ren H, Chang B, Murai M, Amemura-Maekawa J, Ohnishi M. | J Clin Microbiol | 10.1128/jcm.00157-21 | 2021 | | |
| Differences in UV-C LED Inactivation of Legionellapneumophila Serogroups in Drinking Water. | Buse HY, Hall JS, Hunter GL, Goodrich JA. | Microorganisms | 10.3390/microorganisms10020352 | 2022 | | |
| Use of Fourier-Transform Infrared Spectroscopy With IR Biotyper® System for Legionella pneumophila Serogroups Identification. | Pascale MR, Bisognin F, Mazzotta M, Girolamini L, Marino F, Dal Monte P, Cordovana M, Scaturro M, Ricci ML, Cristino S. | Front Microbiol | 10.3389/fmicb.2022.866426 | 2022 | | |
| Microbial Community Establishment, Succession, and Temporal Dynamics in an Industrial Semi-Synthetic Metalworking Fluid Operation: A 50-Week Real-Time Tracking. | Kapoor R, Selvaraju SB, Subramanian V, Yadav JS. | Microorganisms | 10.3390/microorganisms12020267 | 2024 | | |
| Genetics | Genome Sequencing Links Persistent Outbreak of Legionellosis in Sydney (New South Wales, Australia) to an Emerging Clone of Legionella pneumophila Sequence Type 211. | Timms VJ, Rockett R, Bachmann NL, Martinez E, Wang Q, Chen SC, Jeoffreys N, Howard PJ, Smith A, Adamson S, Gilmour R, Sheppeard V, Sintchenko V. | Appl Environ Microbiol | 10.1128/aem.02020-17 | 2018 | |
| Enzymology | Electrophoretic mobility of Legionella pneumophila serogroups 1 to 14. | Buse HY, Hoelle JM, Muhlen C, Lytle DA. | FEMS Microbiol Lett | 10.1093/femsle/fny067 | 2018 | |
| Pathogenicity | Bacterial Long-Range Warfare: Aerial Killing of Legionella pneumophila by Pseudomonas fluorescens. | Corre MH, Mercier A, Bouteiller M, Khalil A, Ginevra C, Depayras S, Dupont C, Rouxel M, Gallique M, Grac L, Jarraud S, Giron D, Merieau A, Berjeaud JM, Verdon J. | Microbiol Spectr | 10.1128/spectrum.00404-21 | 2021 | |
| Highlighting the Potency of Biosurfactants Produced by Pseudomonas Strains as Anti-Legionella Agents. | Loiseau C, Portier E, Corre MH, Schlusselhuber M, Depayras S, Berjeaud JM, Verdon J. | Biomed Res Int | 10.1155/2018/8194368 | 2018 | | |
| Intragenic recombination has a critical role on the evolution of Legionella pneumophila virulence-related effector sidJ. | Costa J, Teixeira PG, d'Avo AF, Junior CS, Verissimo A. | PLoS One | 10.1371/journal.pone.0109840 | 2014 | | |
| Effect of temperature and colonization of Legionella pneumophila and Vermamoeba vermiformis on bacterial community composition of copper drinking water biofilms. | Buse HY, Ji P, Gomez-Alvarez V, Pruden A, Edwards MA, Ashbolt NJ. | Microb Biotechnol | 10.1111/1751-7915.12457 | 2017 | | |
| Pathogenicity | Exposure to synthetic gray water inhibits amoeba encystation and alters expression of Legionella pneumophila virulence genes. | Buse HY, Lu J, Ashbolt NJ. | Appl Environ Microbiol | 10.1128/aem.03394-14 | 2015 | |
| Enzymology | Specific real-time PCR for simultaneous detection and identification of Legionella pneumophila serogroup 1 in water and clinical samples. | Merault N, Rusniok C, Jarraud S, Gomez-Valero L, Cazalet C, Marin M, Brachet E, Aegerter P, Gaillard JL, Etienne J, Herrmann JL, DELPH-I Study Group, Lawrence C, Buchrieser C. | Appl Environ Microbiol | 10.1128/aem.02261-10 | 2011 | |
| Phylogeny | Legionella confirmation using real-time PCR and SYTO9 is an alternative to current methodology. | Giglio S, Monis PT, Saint CP. | Appl Environ Microbiol | 10.1128/aem.71.12.8944-8948.2005 | 2005 | |
| Phylogeny | Two-step scheme for rapid identification and differentiation of Legionella pneumophila and non-Legionella pneumophila species. | Zhan XY, Li LQ, Hu CH, Zhu QY. | J Clin Microbiol | 10.1128/jcm.01778-09 | 2010 | |
| Enzymology | Viability PCR, a culture-independent method for rapid and selective quantification of viable Legionella pneumophila cells in environmental water samples. | Delgado-Viscogliosi P, Solignac L, Delattre JM. | Appl Environ Microbiol | 10.1128/aem.02878-08 | 2009 | |
| Characterization of a tandem repeat polymorphism in Legionella pneumophila and its use for genotyping. | Pourcel C, Vidgop Y, Ramisse F, Vergnaud G, Tram C. | J Clin Microbiol | 10.1128/jcm.41.5.1819-1826.2003 | 2003 | | |
| Enzymology | Quantitative real-time Legionella PCR for environmental water samples: data interpretation. | Joly P, Falconnet PA, Andre J, Weill N, Reyrolle M, Vandenesch F, Maurin M, Etienne J, Jarraud S. | Appl Environ Microbiol | 10.1128/aem.72.4.2801-2808.2006 | 2006 | |
| Characterization of a lipoprotein common to Legionella species as a urinary broad-spectrum antigen for diagnosis of Legionnaires' disease. | Kim MJ, Sohn JW, Park DW, Park SC, Chun BC. | J Clin Microbiol | 10.1128/jcm.41.7.2974-2979.2003 | 2003 | | |
| Phylogeny | Population genetic structure of Legionella pneumophila inferred from RNA polymerase gene (rpoB) and DotA gene (dotA) sequences. | Ko KS, Lee HK, Park MY, Park MS, Lee KH, Woo SY, Yun YJ, Kook YH. | J Bacteriol | 10.1128/jb.184.8.2123-2130.2002 | 2002 | |
| Molecular evolution of the dotA gene in Legionella pneumophila. | Ko KS, Hong SK, Lee HK, Park MY, Kook YH. | J Bacteriol | 10.1128/jb.185.21.6269-6277.2003 | 2003 | | |
| Multiplication of different Legionella species in Mono Mac 6 cells and in Acanthamoeba castellanii. | Neumeister B, Schoniger S, Faigle M, Eichner M, Dietz K. | Appl Environ Microbiol | 10.1128/aem.63.4.1219-1224.1997 | 1997 | | |
| Phylogeny | Identification of legionella species by use of an oligonucleotide array. | Su HP, Tung SK, Tseng LR, Tsai WC, Chung TC, Chang TC. | J Clin Microbiol | 10.1128/jcm.02225-08 | 2009 | |
| Metabolism | Targeting species-specific low-affinity 16S rRNA binding sites by using peptide nucleic acids for detection of Legionellae in biofilms. | Wilks SA, Keevil CW. | Appl Environ Microbiol | 10.1128/aem.02918-05 | 2006 | |
| Enzymology | Detection of legionellae in hospital water samples by quantitative real-time LightCycler PCR. | Wellinghausen N, Frost C, Marre R. | Appl Environ Microbiol | 10.1128/aem.67.9.3985-3993.2001 | 2001 | |
| Enzymology | Presence and persistence of Legionella spp. in groundwater. | Costa J, Tiago I, da Costa MS, Verissimo A. | Appl Environ Microbiol | 10.1128/aem.71.2.663-671.2005 | 2005 | |
| Virulence conversion of Legionella pneumophila by conjugal transfer of chromosomal DNA. | Miyamoto H, Yoshida S, Taniguchi H, Shuman HA. | J Bacteriol | 10.1128/jb.185.22.6712-6718.2003 | 2003 | | |
| Characterization of the alternative sigma factor sigma54 and the transcriptional regulator FleQ of Legionella pneumophila, which are both involved in the regulation cascade of flagellar gene expression. | Jacobi S, Schade R, Heuner K. | J Bacteriol | 10.1128/jb.186.9.2540-2547.2004 | 2004 | | |
| Metabolism | Discovery of a nonclassical siderophore, legiobactin, produced by strains of Legionella pneumophila. | Liles MR, Scheel TA, Cianciotto NP. | J Bacteriol | 10.1128/jb.182.3.749-757.2000 | 2000 | |
| Identification of Legionella pneumophila rcp, a pagP-like gene that confers resistance to cationic antimicrobial peptides and promotes intracellular infection. | Robey M, O'Connell W, Cianciotto NP. | Infect Immun | 10.1128/iai.69.7.4276-4286.2001 | 2001 | | |
| Metabolism | Legionella dumoffii DjlA, a member of the DnaJ family, is required for intracellular growth. | Ohnishi H, Mizunoe Y, Takade A, Tanaka Y, Miyamoto H, Harada M, Yoshida S. | Infect Immun | 10.1128/iai.72.6.3592-3603.2004 | 2004 | |
| Enzymology | Cloning and characterization of the gene encoding the major cell-associated phospholipase A of Legionella pneumophila, plaB, exhibiting hemolytic activity. | Flieger A, Rydzewski K, Banerji S, Broich M, Heuner K. | Infect Immun | 10.1128/iai.72.5.2648-2658.2004 | 2004 | |
| Enzymology | Development of conventional and real-time PCR assays for detection of Legionella DNA in respiratory specimens. | Rantakokko-Jalava K, Jalava J. | J Clin Microbiol | 10.1128/jcm.39.8.2904-2910.2001 | 2001 | |
| Enzymology | Application of RNA polymerase beta-subunit gene (rpoB) sequences for the molecular differentiation of Legionella species. | Ko KS, Lee HK, Park MY, Lee KH, Yun YJ, Woo SY, Miyamoto H, Kook YH. | J Clin Microbiol | 10.1128/jcm.40.7.2653-2658.2002 | 2002 | |
| Cloning and genetic characterization of the flagellum subunit gene (flaA) of Legionella pneumophila serogroup 1. | Heuner K, Bender-Beck L, Brand BC, Luck PC, Mann KH, Marre R, Ott M, Hacker J. | Infect Immun | 10.1128/iai.63.7.2499-2507.1995 | 1995 | | |
| Phylogeny | Multiple types of Legionella pneumophila serogroup 6 in a hospital heated-water system associated with sporadic infections. | Visca P, Goldoni P, Luck PC, Helbig JH, Cattani L, Giltri G, Bramati S, Castellani Pastoris M. | J Clin Microbiol | 10.1128/jcm.37.7.2189-2196.1999 | 1999 | |
| Phylogeny | Antigenic and genetic variation in Legionella pneumophila serogroup 6. | McKinney RM, Kuffner TA, Bibb WF, Nokkaew C, Wells DE, Arnow PM, Woods TC, Plikaytis BD. | J Clin Microbiol | 10.1128/jcm.27.4.738-742.1989 | 1989 | |
| Efficacy of NY-198 against experimental Legionnaires disease. | Kohno S, Yamaguchi K, Dohtsu Y, Koga H, Hayashi T, Hirota M, Saito A, Hara K. | Antimicrob Agents Chemother | 10.1128/aac.32.9.1427 | 1988 | | |
| Detection of Legionella spp. in bronchoalveolar lavage fluids by DNA amplification. | Jaulhac B, Nowicki M, Bornstein N, Meunier O, Prevost G, Piemont Y, Fleurette J, Monteil H. | J Clin Microbiol | 10.1128/jcm.30.4.920-924.1992 | 1992 | | |
| Phase-variable expression of lipopolysaccharide contributes to the virulence of legionella pneumophila. | Luneberg E, Zahringer U, Knirel YA, Steinmann D, Hartmann M, Steinmetz I, Rohde M, Kohl J, Frosch M. | J Exp Med | 10.1084/jem.188.1.49 | 1998 | | |
| Comparison of ribotyping and restriction enzyme analysis using pulsed-field gel electrophoresis for distinguishing Legionella pneumophila isolates obtained during a nosocomial outbreak. | Schoonmaker D, Heimberger T, Birkhead G. | J Clin Microbiol | 10.1128/jcm.30.6.1491-1498.1992 | 1992 | | |
| Identification of mip-like genes in the genus Legionella. | Cianciotto NP, Bangsborg JM, Eisenstein BI, Engleberg NC. | Infect Immun | 10.1128/iai.58.9.2912-2918.1990 | 1990 | | |
| Phylogeny | Characterization of members of the Legionellaceae family by automated ribotyping. | Cordevant C, Tang JS, Cleland D, Lange M. | J Clin Microbiol | 10.1128/jcm.41.1.34-43.2003 | 2003 | |
| Pathogenicity | Susceptibility of Legionella pneumophila to ofloxacin in vitro and in experimental Legionella pneumonia in guinea pigs. | Saito A, Sawatari K, Fukuda Y, Nagasawa M, Koga H, Tomonaga A, Nakazato H, Fujita K, Shigeno Y, Suzuyama Y. | Antimicrob Agents Chemother | 10.1128/aac.28.1.15 | 1985 | |
| Phylogeny | Dye-containing buffered charcoal-yeast extract medium for differentiation of members of the family Legionellaceae. | Vickers RM, Brown A, Garrity GM. | J Clin Microbiol | 10.1128/jcm.13.2.380-382.1981 | 1981 | |
| Monoclonal antibodies to Legionella Mip proteins recognize genus- and species-specific epitopes. | Helbig JH, Ludwig B, Luck PC, Groh A, Witzleb W, Hacker J. | Clin Diagn Lab Immunol | 10.1128/cdli.2.2.160-165.1995 | 1995 | | |
| Phylogeny | Hydroxy-fatty acid profiles of Legionella species: diagnostic usefulness assessed by principal component analysis. | Jantzen E, Sonesson A, Tangen T, Eng J. | J Clin Microbiol | 10.1128/jcm.31.6.1413-1419.1993 | 1993 | |
| Genus-specific epitope on the 60-kilodalton Legionella heat shock protein recognized by a monoclonal antibody. | Steinmetz I, Rheinheimer C, Hubner I, Bitter-Suermann D. | J Clin Microbiol | 10.1128/jcm.29.2.346-354.1991 | 1991 | | |
| Cross-reactions between Legionella pneumophila (serogroup 1) and twenty-eight other bacterial species, including other members of the family Legionellaceae. | Collins MT, Espersen F, Hoiby N, Cho SN, Friis-Moller A, Reif JS. | Infect Immun | 10.1128/iai.39.3.1441-1456.1983 | 1983 | | |
| DNA probe specific for Legionella pneumophila. | Grimont PA, Grimont F, Desplaces N, Tchen P. | J Clin Microbiol | 10.1128/jcm.21.3.431-437.1985 | 1985 | | |
| Phylogeny | Identification and DNA fingerprinting of Legionella strains by randomly amplified polymorphic DNA analysis. | Bansal NS, McDonell F. | J Clin Microbiol | 10.1128/jcm.35.9.2310-2314.1997 | 1997 | |
| Antigenic analysis of Legionella pneumophila and Tatlockia micdadei (Legionella micdadei) by two-dimensional (crossed) immunoelectrophoresis. | Joly JR, Kenny GE. | Infect Immun | 10.1128/iai.35.2.721-729.1982 | 1982 | | |
| Substrate utilization by Legionella cells after cryopreservation in phosphate buffer. | Weiss E, Westfall HN. | Appl Environ Microbiol | 10.1128/aem.48.2.380-385.1984 | 1984 | | |
| Phylogeny | Usefulness of fatty acid composition for differentiation of Legionella species. | Diogo A, Verissimo A, Nobre MF, da Costa MS. | J Clin Microbiol | 10.1128/jcm.37.7.2248-2254.1999 | 1999 | |
| Enzymology | Detection of Legionella species in reclaimed water and air with the EnviroAmp Legionella PCR kit and direct fluorescent antibody staining. | Palmer CJ, Bonilla GF, Roll B, Paszko-Kolva C, Sangermano LR, Fujioka RS. | Appl Environ Microbiol | 10.1128/aem.61.2.407-412.1995 | 1995 | |
| Detection of flagella in 278 Legionella strains by latex reagent sensitized with antiflagellum immunoglobulins. | Bornstein N, Marmet D, Dumaine MH, Surgot M, Fleurette J. | J Clin Microbiol | 10.1128/jcm.29.5.953-956.1991 | 1991 | | |
| Phylogeny | Sequence-based classification scheme for the genus Legionella targeting the mip gene. | Ratcliff RM, Lanser JA, Manning PA, Heuzenroeder MW. | J Clin Microbiol | 10.1128/jcm.36.6.1560-1567.1998 | 1998 | |
| Phylogeny | Development of a DNA microarray method for detection and identification of all 15 distinct O-antigen forms of Legionella pneumophila. | Cao B, Yao F, Liu X, Feng L, Wang L. | Appl Environ Microbiol | 10.1128/aem.01957-13 | 2013 | |
| Phylogeny | Consensus sequence-based scheme for epidemiological typing of clinical and environmental isolates of Legionella pneumophila. | Gaia V, Fry NK, Afshar B, Luck PC, Meugnier H, Etienne J, Peduzzi R, Harrison TG. | J Clin Microbiol | 10.1128/jcm.43.5.2047-2052.2005 | 2005 | |
| Enzymology | Quantitative detection of Legionella pneumophila in water samples by immunomagnetic purification and real-time PCR amplification of the dotA gene. | Yanez MA, Carrasco-Serrano C, Barbera VM, Catalan V. | Appl Environ Microbiol | 10.1128/aem.71.7.3433-3441.2005 | 2005 | |
| Intergenic 16S rRNA gene (rDNA)-23S rDNA sequence length polymorphisms in members of the family Legionellaceae. | Hookey JV, Birtles RJ, Saunders NA. | J Clin Microbiol | 10.1128/jcm.33.9.2377-2381.1995 | 1995 | | |
| Phylogeny | Legionella pneumophila serogroup Lansing 3 isolated from a patient with fatal pneumonia, and descriptions of L. pneumophila subsp. pneumophila subsp. nov., L. pneumophila subsp. fraseri subsp. nov., and L. pneumophila subsp. pascullei subsp. nov. | Brenner DJ, Steigerwalt AG, Epple P, Bibb WF, McKinney RM, Starnes RW, Colville JM, Selander RK, Edelstein PH, Moss CW. | J Clin Microbiol | 10.1128/jcm.26.9.1695-1703.1988 | 1988 | |
How to citeIf you want to cite this particular strain cite the following doi:
https://doi.org/10.13145/bacdive6721.20260601.11
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BacDive in 2025: the core database for prokaryotic strain data
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