Name: Lacticaseibacillus casei 03
Creator: BacDive
License: http://creativecommons.org/licenses/by-nc/4.0/

Strain identifier

BacDive ID: 6559

Type strain:

Species: Lacticaseibacillus casei

Strain Designation: 03, 7, O3

Culture col. no.: CCUG 21451, IAM 12473, LMG 6904, DSM 20011, ATCC 393, NCDO 161, WDCM 00100, JCM 1134, BCRC 10697, CECT 475, CIP 103137, IFO 15883, KCTC 3109, NBRC 15883, NCIMB 11970, NRRL B-1922, VTT E-85225, IID 892, CCM 7088, NCTC 13641

Strain history: CIP <- 1998, DSM, <- ATCC <- G. J. Hucker: strain O3 <- S. Orla-Jensen: strain 7, Streptobacterium casei

NCBI tax ID(s): 1582 (species)

SI-ID 9751

LMG 9190, ATCC 393, CECT 475, DSM 20011, IAM 12473, JCM 1134, LMG 6904, NCFB 161, NCIMB 11970, CCUG 21451, NCDO 161, CIP 103137, NCIB 11970, CCRC 10697, IFO 15883, KCTC 3109, HAMBI 85, VTT E-85225, CECT 5275, NRRL B-1922, KCTC 3110, NBRC 15883, CCM 7088, BCC 4308, BCRC 10697, CCT 3750, CCT 1465, CDBB 794, CDBB 382, BCRC 17646, CCRC 17646, VTT E-001744, VTT E-001745

Other strains from Lacticaseibacillus casei

L. casei pLZ15, CIP 109805
L. casei JCM 20024, ATU L-29, IAM 1045
L. casei JCM 20304, IAM 10062
L. casei JCM 2120, ATCC 4913
L. casei JCM 8129, BCRC 17487, NCDO 173
L. casei JCM 8608
L. casei JCM 8615
L. casei JCM 8621
L. casei JCM 8648
L. casei JCM 8677

Section

Lacticaseibacillus casei 03 is a facultative anaerobe human pathogen that was isolated from cheese.

facultative anaerobe
human pathogen
16S sequence
Bacteria
genome sequence

Information on the name and the taxonomic classification. Name and taxonomic classification

	Last LPSN update	14-12-2023 (DD-MM-YYYY)
	Domain	"Bacteria"
	Phylum	*Bacillota*
	Class	*Bacilli*
	Order	*Lactobacillales*
	Family	*Lactobacillaceae*
	Genus	*Lacticaseibacillus*
	Species	**Lacticaseibacillus casei**
	Full Scientific Name (LPSN)	Lacticaseibacillus casei (Orla-Jensen 1916) Zheng et al. 2020

	Synonym	Lactobacillus casei
	Synonym	"Caseobacterium* vulgare"*

Information on morphological and physiological properties Morphology

[Ref.: #117199]	Gram stain	positive
[Ref.: #69480]	Gram stain	positive Confidence in %100

[Ref.: #117199]	Cell shape	rod-shaped

[Ref.: #117199]	Motility	no
[Ref.: #69480]	Motility	no Confidence in %96.635

Information on culture and growth conditions Culture and growth conditions

[Ref.: #8425]

Culture medium

MRS MEDIUM (DSMZ Medium 11)

[Ref.: #8425]

Culture medium growth

[Ref.: #8425]

Culture medium link

Medium recipe at MediaDive

[Ref.: #8425]

Culture medium composition

expand / minimize

[Ref.: #41833]

Culture medium

MEDIUM 40- for Lactobacillus and Leuconostoc

[Ref.: #41833]

Culture medium growth

[Ref.: #41833]

Culture medium composition

expand / minimize

[Ref.: #117199]

Culture medium

CIP Medium 40

[Ref.: #117199]

Culture medium growth

[Ref.: #117199]

Culture medium link

Medium recipe provided by DSMZ

	Kind of temperature		Temperature
[Ref.: #8425]		growth	30 °C
[Ref.: #22930]		growth	15-45 °C
[Ref.: #41833]		growth	37 °C
[Ref.: #67770]		growth	37 °C
[Ref.: #117199]		growth	15-45 °C
[Ref.: #117199]	no	growth	10 °C

[Ref.: #8425]	Temperature range	mesophilic
[Ref.: #41833]	Temperature range	mesophilic
[Ref.: #67770]	Temperature range	mesophilic
[Ref.: #117199]	Temperature range	psychrophilic

Information on physiology and metabolism Physiology and metabolism

[Ref.: #117199]

Oxygen tolerance

facultative anaerobe

[Ref.: #117199]	Ability of spore formation	no
[Ref.: #69481]	Ability of spore formation	no Confidence in %100
[Ref.: #69480]	Ability of spore formation	no Confidence in %99.99

[Ref.: #8425]	Name of produced compound	acetoin
[Ref.: #8425]	Name of produced compound	diacetyl

[Ref.: #8425]	Murein short key	A11.31
[Ref.: #8425]	Murein types	A4alpha L-Lys-D-Asp

	Metabolite	Utilization activity	Kind of utilization tested
[Ref.: #22930]	amygdalin ChEBI	+	growth
[Ref.: #68371]	amygdalin ChEBI	+	builds acid from	* from API 50CH acid
[Ref.: #68371]	arbutin ChEBI	+	builds acid from	* from API 50CH acid
[Ref.: #68371]	cellobiose ChEBI	+	builds acid from	* from API 50CH acid
[Ref.: #68371]	D-arabinose ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	D-arabitol ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	D-fructose ChEBI	+	builds acid from	* from API 50CH acid
[Ref.: #68371]	D-fucose ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	D-galactose ChEBI	+	builds acid from	* from API 50CH acid
[Ref.: #68371]	D-glucose ChEBI	+	builds acid from	* from API 50CH acid
[Ref.: #22930]	D-lyxose ChEBI	-	growth
[Ref.: #68371]	D-lyxose ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	D-mannitol ChEBI	+	builds acid from	* from API 50CH acid
[Ref.: #68379]	D-mannitol ChEBI	+	fermentation	* from API Coryne
[Ref.: #68371]	D-mannose ChEBI	+	builds acid from	* from API 50CH acid
[Ref.: #68371]	D-ribose ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68379]	D-ribose ChEBI	-	fermentation	* from API Coryne
[Ref.: #68371]	D-sorbitol ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	D-xylose ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68379]	D-xylose ChEBI	-	fermentation	* from API Coryne
[Ref.: #68371]	erythritol ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	esculin ChEBI	+	builds acid from	* from API 50CH acid
[Ref.: #68379]	esculin ChEBI	+	hydrolysis	* from API Coryne
[Ref.: #68371]	galactitol ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68379]	gelatin ChEBI	-	hydrolysis	* from API Coryne
[Ref.: #68371]	glycerol ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	glycogen ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68379]	glycogen ChEBI	-	fermentation	* from API Coryne
[Ref.: #68371]	inulin ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	L-arabinose ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	L-arabitol ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	L-fucose ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	L-rhamnose ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #22930]	L-sorbose ChEBI	-	growth
[Ref.: #68371]	L-sorbose ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	L-xylose ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	lactose ChEBI	+	builds acid from	* from API 50CH acid
[Ref.: #68379]	lactose ChEBI	+	fermentation	* from API Coryne
[Ref.: #68379]	maltose ChEBI	+	fermentation	* from API Coryne
[Ref.: #68371]	maltose ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #22930]	melezitose ChEBI	+	growth
[Ref.: #68371]	melezitose ChEBI	+	builds acid from	* from API 50CH acid
[Ref.: #68371]	melibiose ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	methyl alpha-D-glucopyranoside ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	methyl alpha-D-mannoside ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	methyl beta-D-xylopyranoside ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	myo-inositol ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	N-acetylglucosamine ChEBI	+	builds acid from	* from API 50CH acid
[Ref.: #117199]	nitrate ChEBI	-	reduction
[Ref.: #117199]	nitrate ChEBI	+	respiration
[Ref.: #68379]	nitrate ChEBI	+	reduction	* from API Coryne
[Ref.: #117199]	nitrite ChEBI	-	reduction
[Ref.: #68371]	Potassium 2-ketogluconate ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	Potassium 5-ketogluconate ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	raffinose ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #22930]	ribitol ChEBI	-	growth
[Ref.: #68371]	ribitol ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #22930]	ribose ChEBI	-	growth
[Ref.: #68371]	salicin ChEBI	+	builds acid from	* from API 50CH acid
[Ref.: #22930]	sorbitol ChEBI	-	growth
[Ref.: #68371]	starch ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #22930]	sucrose ChEBI	-	growth
[Ref.: #68379]	sucrose ChEBI	+	fermentation	* from API Coryne
[Ref.: #68371]	trehalose ChEBI	+	builds acid from	* from API 50CH acid
[Ref.: #22930]	turanose ChEBI	-	growth
[Ref.: #68371]	turanose ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68379]	urea ChEBI	-	hydrolysis	* from API Coryne
[Ref.: #68371]	xylitol ChEBI	-	builds acid from	* from API 50CH acid
	Only first 10 entries are displayed. Click here to see all.

	Physiological tests	Metabolite	Voges-Proskauer-test
[Ref.: #117199]		acetoin ChEBI	+

	Enzyme	Enzyme activity	EC number
[Ref.: #68382]	acid phosphatase	+	3.1.3.2	* from API zym
[Ref.: #117199]	alcohol dehydrogenase	-	1.1.1.1
[Ref.: #68382]	alkaline phosphatase	+	3.1.3.1	* from API zym, API Coryne
[Ref.: #68382]	alpha-chymotrypsin	+	3.4.21.1	* from API zym
[Ref.: #68382]	alpha-fucosidase	-	3.2.1.51	* from API zym
[Ref.: #68382]	alpha-galactosidase	-	3.2.1.22	* from API zym
[Ref.: #68382]	alpha-glucosidase	-	3.2.1.20	* from API zym, API Coryne
[Ref.: #68382]	alpha-mannosidase	-	3.2.1.24	* from API zym
[Ref.: #68382]	beta-galactosidase	+	3.2.1.23	* from API zym, API Coryne
[Ref.: #68382]	beta-glucosidase	+	3.2.1.21	* from API zym, API Coryne
[Ref.: #68382]	beta-glucuronidase	-	3.2.1.31	* from API zym, API Coryne
[Ref.: #117199]	catalase	-	1.11.1.6
[Ref.: #68379]	catalase	+	1.11.1.6	* from API Coryne
[Ref.: #68382]	cystine arylamidase	+	3.4.11.3	* from API zym
[Ref.: #68382]	esterase (C 4)	+		* from API zym
[Ref.: #68382]	esterase lipase (C 8)	+		* from API zym
[Ref.: #68379]	gelatinase	-		* from API Coryne
[Ref.: #68382]	leucine arylamidase	+	3.4.11.1	* from API zym
[Ref.: #68382]	lipase (C 14)	+		* from API zym
[Ref.: #117199]	lysine decarboxylase	-	4.1.1.18
[Ref.: #68382]	N-acetyl-beta-glucosaminidase	-	3.2.1.52	* from API zym, API Coryne
[Ref.: #68382]	naphthol-AS-BI-phosphohydrolase	+		* from API zym
[Ref.: #117199]	ornithine decarboxylase	-	4.1.1.17
[Ref.: #117199]	oxidase	-
[Ref.: #68379]	pyrazinamidase	-	3.5.1.B15	* from API Coryne
[Ref.: #68379]	pyrrolidonyl arylamidase	+	3.4.19.3	* from API Coryne
[Ref.: #68382]	trypsin	-	3.4.21.4	* from API zym
[Ref.: #68379]	urease	-	3.5.1.5	* from API Coryne
[Ref.: #68382]	valine arylamidase	+		* from API zym
	Only first 10 entries are displayed. Click here to see all.

API® 50CH acid:

Note that the displayed test results represent raw data and therefore may deviate!

	API ID	ControlQ	Acid from glycerolGLY	Acid from erythritolERY	Acid from D-arabinoseDARA	Acid from L-arabinoseLARA	Acid from D-riboseRIB	Acid from D-xyloseDXYL	Acid from L-xyloseLXYL	Acid from D-adonitolADO	Acid from methyl beta-D-xylopyranosideMDX	Acid from D-galactoseGAL	Acid from D-glucoseGLU	Acid from D-fructoseFRU	Acid from D-mannoseMNE	Acid from L-sorboseSBE	Acid from L-rhamnoseRHA	Acid from dulcitolDUL	Acid from inositolINO	Acid from D-mannitolMAN	Acid from D-sorbitolSOR	Acid from methyl alpha-D-mannopyranosideMDM	Acid from methyl alpha-D-glucopyranosideMDG	Acid from N-acetyl-glucosamineNAG	Acid from amygdalinAMY	Acid from arbutinARB	Acid from esculinESC	Acid from salicinSAL	Acid from cellobioseCEL	Acid from maltoseMAL	Acid from lactoseLAC	Acid from melibioseMEL	Acid from sucroseSAC	Acid from trehaloseTRE	Acid from inulinINU	Acid from melezitoseMLZ	Acid from raffinoseRAF	Acid from starchAMD	Acid from glycogenGLYG	Acid from xylitolXLT	Acid from gentiobioseGEN	Acid from turanoseTUR	Acid from D-lyxoseLYX	Acid from D-tagatoseTAG	Acid from D-fucoseDFUC	Acid from L-fucoseLFUC	Acid from D-arabitolDARL	Acid from L-arabitolLARL	Acid from gluconateGNT	Acid from 2-Ketogluconate2KG	Acid from 5-Ketogluconate5KG
[Ref.: #8425]	14959	-	-	-	-	-	-	-	-	-	-	+	+	+	+	-	-	-	-	+	-	-	-	+	+	+	+	+	+	-	+	-	-	+	-	+	-	-	-	-	+	-	-	+	-	-	-	-	-	-	-
[Ref.: #8425]	14906	-	-	-	-	-	-	-	-	-	-	+	+	+	+	-	-	-	-	+	-	-	-	+	+	+	+	+	+	-	+	-	-	+	-	+	-	-	-	-	+	-	-	+	-	-	-	-	-	-	-
[Ref.: #8425]	14432	-	-	-	-	-	-	-	-	-	-	+	+	+	+	-	-	-	-	+	-	-	-	+	+	+	+	+	+	-	+	-	-	+	-	+	-	-	-	-	-	-	-	+	-	-	-	-	-	-	-
[Ref.: #8425]	14431	-	-	-	-	-	-	-	-	-	-	+	+	+	+	-	-	-	-	+	-	-	-	+	+	+	+	+	+	-	+	-	-	+	-	+	-	-	-	-	-	-	-	+	-	-	-	-	-	-	-
[Ref.: #8425]	14430	-	-	-	-	-	-	-	-	-	-	+	+	+	+	-	-	-	-	+	-	-	-	+	+	+	+	+	+	-	+	-	-	+	-	+	-	-	-	-	+	-	-	+	-	-	-	-	+	-	-
[Ref.: #8425]	14429	-	-	-	-	-	-	-	-	-	-	+	+	+	+	-	-	-	-	+	-	-	-	+	+	+	+	+	+	-	+	-	-	+	-	+	-	-	-	-	+	-	-	+	-	-	-	-	+	-	-
[Ref.: #8425]	14428	-	-	-	-	-	-	-	-	-	-	+	+	+	+	-	-	-	-	+	-	-	-	+	+	+	+	+	+	-	+	-	+/-	+	-	+	-	-	-	-	+	-	-	+	-	-	-	-	+	-	-
[Ref.: #8425]	14427	-	-	-	-	-	-	-	-	-	-	+	+	+	+	-	-	-	-	+	-	-	-	+	+	+	+	+	+	-	+	-	-	+	-	+	-	-	-	-	+	-	-	-	-	-	-	-	+	-	-

API® Coryne:

Note that the displayed test results represent raw data and therefore may deviate!

	API ID	Reduction of nitrateNIT	PyrazinamidasePYZ	Pyrrolidonyl arylamidasePYRA	Alkaline phosphatasePAL	beta-Glucuronidasebeta GUR	beta-Galactosidasebeta GAL	alpha-Glucosidasealpha GLU	N-Acetyl-beta-Glucosidasebeta NAG	Esculin hydrolysis/beta-GlucosidaseESC	Urease/urea hydrolysisURE	Gelatinase/gelatin hydrolysisGEL	Control fermentationControl	Fermentation of D-glucoseGLU	Fermentation of D-riboseRIB	Fermentation of D-xyloseXYL	Fermentation of D-mannitolMAN	Fermentation of maltoseMAL	Fermentation of lactoseLAC	Fermentation of sucroseSAC	Fermentation of glycogenGLYG	CatalaseCAT
[Ref.: #47412]	844	+	-	+	+	-	+	-	-	+	-	-	-	not determinedn.d.	-	-	+	+	+	+	-	+

API® zym:

Note that the displayed test results represent raw data and therefore may deviate!

	API ID	Control	2-naphthyl phosphateAlkaline phosphatase	2-naphthyl butyrateEsterase (C 4)	2-naphtyl caprylateEsterase Lipase (C 8)	2-naphthyl myristateLipase (C 14)	L-leucyl-2-naphthylamideLeucine arylamidase	L-valyl-2-naphthylamideValine arylamidase	L-cystyl-2-naphthylamideCystine arylamidase	N-benzoyl-DL-arginine-2-naphthylamideTrypsin	N-glutaryl-phenylalanine-2-naphthylamidealpha- Chymotrypsin	2-naphthyl phosphateAcid phosphatase	Naphthol-AS-BI-phosphateNaphthol-AS-BI-phosphohydrolase	6-Br-2-naphthyl-alphaD-galactpyranosidealpha- Galactosidase	2-naphthyl-betaD-galactpyranosidebeta- Galactosidase	Naphthol-AS-BI-betaD-glucuronidebeta- Glucuronidase	2-naphthyl-alphaD-glucopyranosidealpha- Glucosidase	6-Br-2-naphthyl-betaD-glucopyranosidebeta- Glucosidase	1-naphthyl-N-acetyl-betaD-glucosaminideN-acetyl-beta- glucosaminidase	6-Br-2-naphthyl-alphaD-mannopyranosidealpha- Mannosidase	2-naphthyl-alphaL-fucopyranosidealpha- Fucosidase
[Ref.: #117199]	7386	-	+	+	+	+	+	+	+	-	+	+	+	-	+	-	-	+	-	-	-

Information on isolation source, the sampling and environmental conditions Isolation, sampling and environmental information

[Ref.: #8425]	Sample type/isolated from	cheese

[Ref.: #47412]	Sample type/isolated from	Cheese

[Ref.: #67770]	Sample type/isolated from	Cheese

[Ref.: #117199]	Sample type/isolated from	Food, Cheese
* marker position based on {}

Isolation sources categories

#Engineered

#Food production

#Dairy product

What are isolation sources categories?

[Ref.: #69479]

Global distribution of 16S sequence LC064894 (>99% sequence identity) for Lactobacillaceae from Microbeatlas

Aquatic Samples	2397
Soil Samples	1801
Animal Samples	39363
Plant Samples	883
Total Samples	44444

Information on possible application of the strain and its possible interaction with e.g. potential hosts Safety information

[Ref.: #8425]	Pathogenicity (human)	yes, in single cases
[Ref.: #8425]	Biosafety level	1	Risk group (German classification) According to TRBA 466
[Ref.: #117199]	Biosafety level	1	Risk group (French classification)

Information on genomic background e.g. entries in nucleic sequence databass Sequence information

16S Sequence information:

Only first 5 entries are displayed. Click here to see all.

	Sequence accession description	Seq. accession number	Sequence length (bp)	Sequence database	Associated NCBI tax ID
[Ref.: #67770]	Lactobacillus casei gene for 16S ribosomal RNA, partial sequence, strain: JCM 1134	LC064894	1468	ENA	1423732 tax ID
[Ref.: #20218]	Lactobacillus zeae gene for 16S rRNA, partial sequence, strain: YIT 0078 (= ATCC 393)	AB008212	1563	ENA	57037 tax ID	*
[Ref.: #20218]	Lactobacillus casei strain BL23 16S ribosomal RNA gene, partial sequence	AF385770	1518	ENA	543734 tax ID	*
[Ref.: #20218]	Lactobacillus zeae ATCC 393 16S ribosomal RNA gene, partial sequence	AF429500	507	ENA	219334 tax ID	*
[Ref.: #20218]	Lactobacillus zeae strain ATCC 393 16S ribosomal RNA gene, partial sequence; 16S-23S intergenic spacer, complete sequence; and 23S ribosomal RNA gene, partial sequence	AF429587	537	ENA	219334 tax ID	*
[Ref.: #20218]	Lactobacillus casei strain ATCC 393 16S ribosomal RNA gene, partial sequence	AF469172	1517	ENA	219334 tax ID	*
[Ref.: #20218]	Lactobacillus casei subsp. casei ATCC 393 16S ribosomal RNA gene, partial sequence	AY196978	518	ENA	219334 tax ID	*
[Ref.: #20218]	L.casei small subunit ribosomal RNA	M23928	1574	ENA	1582 tax ID	*
[Ref.: #20218]	L.casei rrn operon, 16S-23S rRNA spacer (long), tRNA-Ile and tRNA-Ala genes	Z75478	432	ENA	219334 tax ID	*
[Ref.: #20218]	L.casei rrn operon, 16S-23S rRNA spacer (short)	Z75479	218	ENA	219334 tax ID	*
[Ref.: #20218]	Lactobacillus casei strain BCRC10697 16S ribosomal RNA gene, complete sequence	AY773945	1528	ENA	1582 tax ID	*
[Ref.: #20218]	Lactobacillus casei strain CECT 5275 16S ribosomal RNA gene, partial sequence	AY196967	518	ENA	1582 tax ID	*
[Ref.: #20218]	Lactobacillus casei strain DSM 20011 16S ribosomal RNA gene, partial sequence	EF468100	619	ENA	1582 tax ID	*
[Ref.: #20218]	Lactobacillus casei genes for 16S rRNA, 16S-23S internal transcribed spacer, tRNA-Ile, tRNA-Ala, 23S rRNA, partial and complete sequence, strain:JCM 1134	AB237516	577	ENA	219334 tax ID	*
[Ref.: #20218]	Lactobacillus casei genes for 16S rRNA, 16S-23S internal transcribed spacer, 23S rRNA, partial sequence, strain:JCM 1134	AB237517	364	ENA	219334 tax ID	*
[Ref.: #20218]	Lactobacillus casei gene for 16S rRNA, partial sequence, strain: JCM 1134	AB289057	681	ENA	219334 tax ID	*
[Ref.: #20218]	Lactobacillus casei subsp. casei 16S ribosomal RNA, partial sequence; 16S/23S intergenic spacer region, complete sequence; and 23S ribosomal RNA partial sequence	AF182729	685	ENA	219334 tax ID	*
[Ref.: #20218]	Lactobacillus casei gene for 16S rRNA	D16551	1522	ENA	219334 tax ID	*
[Ref.: #20218]	Lactobacillus casei gene for 16S rRNA, partial sequence, strain: NBRC 15883	AB626050	1495	ENA	1582 tax ID	*
[Ref.: #20218]	L.casei 16S rRNA gene	X61135	1491	ENA	219334 tax ID	*

Genome sequence information:

Only first 5 entries are displayed. Click here to see all.

	Sequence accession description	Seq. accession number	Assembly level	Sequence database	Associated NCBI tax ID
[Ref.: #67770]	Lacticaseibacillus casei DSM 20011 = JCM 1134 = ATCC 393	GCA_001433735	scaffold	GenBank	1423732 tax ID
[Ref.: #66792]	Lacticaseibacillus casei DSM 20011 = JCM 1134 = ATCC 393	GCA_000615205	contig	GenBank	1423732 tax ID	*
[Ref.: #66792]	Lactobacillus casei DSM 20011 = JCM 1134	1423732.4	wgs	PATRIC	1423732 tax ID	*
[Ref.: #66792]	Lactobacillus casei JCM 1134	1236939.3	wgs	PATRIC	1423732 tax ID	*
[Ref.: #66792]	Lactobacillus casei subsp. casei ATCC 393	219334.10	plasmid	PATRIC	1423732 tax ID	*
[Ref.: #66792]	Lactobacillus casei subsp. casei ATCC 393	219334.11	plasmid	PATRIC	1423732 tax ID	*

[Ref.: #8425]	GC-content	49.0 mol%
[Ref.: #67770]	GC-content	46.5 mol%	genome sequence analysis
[Ref.: #67770]	GC-content	49 mol%

Data predicted using genome information as a basis Genome-based predictions

	Trait	Prediction	Confidence in %	In training data
	Predictions from GenomeNet Sporulation v. 1 based on: Lacticaseibacillus casei DSM 20011 = JCM 1134 = ATCC 393 ATCC 393 NCBI: GCA_000829055.1
[Ref.: #69481]	spore-forming	no	100	no

	Trait	Prediction	Confidence in %	In training data
	Predictions from Diaspora project based on: Lacticaseibacillus casei DSM 20011 = JCM 1134 = ATCC 393 ATCC 393 NCBI: GCA_000829055.1
[Ref.: #69480]	motile	no	94.27	no
[Ref.: #69480]	flagellated	no	98.222	no
[Ref.: #69480]	gram-positive	yes	94.192	no
[Ref.: #69480]	anaerobic	no	94.723	no
[Ref.: #69480]	aerobic	no	94.8	no
[Ref.: #69480]	halophile	yes	79.581	no
[Ref.: #69480]	spore-forming	no	91.345	no
[Ref.: #69480]	glucose-util	yes	91.572	no
[Ref.: #69480]	thermophile	no	98.541	yes
[Ref.: #69480]	glucose-ferment	yes	87.545	no

Availability in culture collections External links

[Ref.: #8425]

Culture collection no.

CCUG 21451, IAM 12473, LMG 6904, DSM 20011, ATCC 393, NCDO 161, WDCM 00100, JCM 1134, BCRC 10697, CECT 475, CIP 103137, IFO 15883, KCTC 3109, NBRC 15883, NCIMB 11970, NRRL B-1922, VTT E-85225, IID 892, CCM 7088, NCTC 13641

[Ref.: #76030]

SI-ID 9751

Literature:

Only first 10 entries are displayed. Click here to see all.

	Title	Authors	Journal	DOI	Year
Metabolism	The Role of Vasoactive Intestinal Peptide and Mast Cells in the Regulatory Effect of Lactobacillus casei ATCC 393 on Intestinal Mucosal Immune Barrier.	Song X, Pi S, Gao Y, Zhou F, Yan S, Chen Y, Qiao L, Dou X, Shao D, Xu C	Front Immunol	10.3389/fimmu.2021.723173	2021	*
Metabolism	Lactobacillus casei ATCC 393 and it's metabolites alleviate dextran sulphate sodium-induced ulcerative colitis in mice through the NLRP3-(Caspase-1)/IL-1beta pathway.	Dou X, Qiao L, Chang J, Yan S, Song X, Chen Y, Xu Q, Xu C	Food Funct	10.1039/d1fo02405a	2021	*
Phylogeny	Isolation and Characterization of Membrane Vesicles from Lactobacillus Species.	Caruana JC, Dean SN, Walper SA	Bio Protoc	10.21769/BioProtoc.4145	2021	*
Pathogenicity	Tailored synbiotic powder (functional food) to prevent hyperphosphataemia (kidney disorder).	Anand A, Yoshida S, Aoyagi H	Sci Rep	10.1038/s41598-021-95176-3	2021	*
Pathogenicity	Biogenic selenium nanoparticles by Lactobacillus casei ATCC 393 alleviate the intestinal permeability, mitochondrial dysfunction and mitophagy induced by oxidative stress.	Yan S, Qiao L, Dou X, Song X, Chen Y, Zhang B, Xu C	Food Funct	10.1039/d0fo03141k	2021	*
Phylogeny	Genome-based reclassification of Lactobacillus casei: emended classification and description of the species Lactobacillus zeae.	Huang CH, Chen CC, Liou JS, Lee AY, Blom J, Lin YC, Huang L, Watanabe K	Int J Syst Evol Microbiol	10.1099/ijsem.0.003969	2020	*
Pathogenicity	Biogenic selenium nanoparticles synthesized by Lactobacillus casei ATCC 393 alleviate diquat-induced intestinal barrier dysfunction in C57BL/6 mice through their antioxidant activity.	Qiao L, Dou X, Yan S, Zhang B, Xu C	Food Funct	10.1039/d0fo00132e	2020	*
Metabolism	Lactobacillus casei ATCC 393 alleviates Enterotoxigenic Escherichia coli K88-induced intestinal barrier dysfunction via TLRs/mast cells pathway.	Xu C, Yan S, Guo Y, Qiao L, Ma L, Dou X, Zhang B	Life Sci	10.1016/j.lfs.2020.117281	2020	*
Phylogeny	A High Throughput Isolation Method for Phosphate-Accumulating Organisms.	Anand A, Aoyagi H	Sci Rep	10.1038/s41598-019-53429-2	2019	*
Cultivation	Topical Delivery of Lactobacillus Culture Supernatant Increases Survival and Wound Resolution in Traumatic Acinetobacter baumannii Infections.	Stanbro J, Park JM, Bond M, Stockelman MG, Simons MP, Watters C	Probiotics Antimicrob Proteins	10.1007/s12602-019-09603-z	2020	*
Metabolism	Exploring encapsulation strategies as a protective mechanism to avoid amensalism in mixed populations of Pseudomonas taetrolens and Lactobacillus casei.	Garcia C, Ranieri G, Rendueles M, Diaz M	Bioprocess Biosyst Eng	10.1007/s00449-019-02204-8	2019	*
Pathogenicity	Biogenic selenium nanoparticles synthesized by Lactobacillus casei ATCC 393 alleviate intestinal epithelial barrier dysfunction caused by oxidative stress via Nrf2 signaling-mediated mitochondrial pathway.	Xu C, Qiao L, Ma L, Guo Y, Dou X, Yan S, Zhang B, Roman A	Int J Nanomedicine	10.2147/IJN.S199193	2019	*
Metabolism	Estimation of microbial phosphate-accumulation abilities.	Anand A, Aoyagi H	Sci Rep	10.1038/s41598-018-37752-8	2019	*
Pathogenicity	Lactobacillus paracasei K5 displays adhesion, anti-proliferative activity and apoptotic effects in human colon cancer cells.	Chondrou P, Karapetsas A, Kiousi DE, Tsela D, Tiptiri-Kourpeti A, Anestopoulos I, Kotsianidis I, Bezirtzoglou E, Pappa A, Galanis A	Benef Microbes	10.3920/BM2017.0183	2018	*
Metabolism	Construction of Lactobacillus casei ghosts by Holin-mediated inactivation and the potential as a safe and effective vehicle for the delivery of DNA vaccines.	Hou R, Li M, Tang T, Wang R, Li Y, Xu Y, Tang L, Wang L, Liu M, Jiang Y, Cui W, Qiao X	BMC Microbiol	10.1186/s12866-018-1216-6	2018	*
Pathogenicity	Preparation, characteristics and antioxidant activity of polysaccharides and proteins-capped selenium nanoparticles synthesized by Lactobacillus casei ATCC 393.	Xu C, Qiao L, Guo Y, Ma L, Cheng Y	Carbohydr Polym	10.1016/j.carbpol.2018.04.110	2018	*
Metabolism	Adsorption preference for divalent metal ions by Lactobacillus casei JCM1134.	Endo R, Aoyagi H	Appl Microbiol Biotechnol	10.1007/s00253-018-9050-1	2018	*
Pathogenicity	Probiotic Lactobacillus sp. inhibit growth, biofilm formation and gene expression of caries-inducing Streptococcus mutans.	Wasfi R, Abd El-Rahman OA, Zafer MM, Ashour HM	J Cell Mol Med	10.1111/jcmm.13496	2018	*
Metabolism	Recombinant Lactobacillus casei expressing Clostridium perfringens toxoids alpha, beta2, epsilon and beta1 gives protection against Clostridium perfringens in rabbits.	Zhao L, Guo Z, Liu J, Wang Z, Wang R, Li Y, Wang L, Xu Y, Tang L, Qiao X	Vaccine	10.1016/j.vaccine.2017.05.076	2017	*
Enzymology	A Recombinant Probiotic, Lactobacillus casei, Expressing the Clostridium perfringens alpha-toxoid, as an Orally Vaccine Candidate Against Gas Gangrene and Necrotic Enteritis.	Alimolaei M, Golchin M, Abshenas J, Ezatkhah M, Bafti MS	Probiotics Antimicrob Proteins	10.1007/s12602-017-9276-8	2018	*
Pathogenicity	Protective Effect of Lactobacillus casei on DMH-Induced Colon Carcinogenesis in Mice.	Irecta-Najera CA, Del Rosario Huizar-Lopez M, Casas-Solis J, Castro-Felix P, Santerre A	Probiotics Antimicrob Proteins	10.1007/s12602-017-9253-2	2017	*
Pathogenicity	Prophylactic Effect of Lactobacillus pentosus strain S-PT84 on Candida Infection and Gastric Inflammation in a Murine Gastrointestinal Candidiasis Model [Errata].	Maekawa T, Ishijima AS, Ida M, Izumo T, Ono Y, Shibata H, Abe S	Med Mycol J	10.3314/mmj.16-00012E	2016	*
Pathogenicity	Prophylactic Effect of Lactobacillus pentosus strain S-PT84 on Candida Infection and Gastric Inflammation in a Murine Gastrointestinal Candidiasis Model.	Maekawa T, Ishijima AS, Ida M, Izumo T, Ono Y, Shibata H, Abe S	Med Mycol J	10.3314/mmj.16-00012	2016	*
Metabolism	Lactobacillus pentosus expressing porcine lactoferrin elevates antibacterial activity and improves the efficacy of vaccination against Aujeszky's disease.	Xu Y, Zong X, Han B, Li Y, Tang L	Acta Vet Hung	10.1556/004.2016.028	2016	*
Pathogenicity	Effect of oligosaccharides on the adhesion of gut bacteria to human HT-29 cells.	Altamimi M, Abdelhay O, Rastall RA	Anaerobe	10.1016/j.anaerobe.2016.03.010	2016	*
Metabolism	Lactobacillus casei Exerts Anti-Proliferative Effects Accompanied by Apoptotic Cell Death and Up-Regulation of TRAIL in Colon Carcinoma Cells.	Tiptiri-Kourpeti A, Spyridopoulou K, Santarmaki V, Aindelis G, Tompoulidou E, Lamprianidou EE, Saxami G, Ypsilantis P, Lampri ES, Simopoulos C, Kotsianidis I, Galanis A, Kourkoutas Y, Dimitrellou D, Chlichlia K	PLoS One	10.1371/journal.pone.0147960	2016	*
Biotechnology	Effect of refrigerated storage on probiotic viability and the production and stability of antimutagenic and antioxidant peptides in yogurt supplemented with pineapple peel.	Sah BN, Vasiljevic T, McKechnie S, Donkor ON	J Dairy Sci	10.3168/jds.2015-9450	2015	*
Enzymology	Isolation and Characterization of a Novel Virulent Phage of Lactobacillus casei ATCC 393.	Zhang X, Lan Y, Jiao W, Li Y, Tang L, Jiang Y, Cui W, Qiao X	Food Environ Virol	10.1007/s12560-015-9206-4	2015	*
Metabolism	Secretory expression of a phospholipase A2 from Lactobacillus casei DSM20011 in Kluyveromyces lactis.	Wang H, Zhang L, Shi G	J Biosci Bioeng	10.1016/j.jbiosc.2015.03.022	2015	*
Metabolism	[Comparison of expression and antibacterial activities of recombinant porcine lactoferrin expressed in four Lactobacillus species].	Yu H, Jiang Y, Cui W, Wu X, He J, Qiao X, Li Y, Tang L	Sheng Wu Gong Cheng Xue Bao		2014	*
Stress	Effect of immobilized Lactobacillus casei on volatile compounds of heat treated probiotic dry-fermented sausages.	Sidira M, Kandylis P, Kanellaki M, Kourkoutas Y	Food Chem	10.1016/j.foodchem.2015.01.068	2015	*
Metabolism	C/EBPalpha controls mast cell function.	Kasakura K, Takahashi K, Itoh T, Hosono A, Nunomura S, Ra C, Momose Y, Itoh K, Nishiyama C, Kaminogawa S	FEBS Lett	10.1016/j.febslet.2014.10.036	2014	*
Biotechnology	Effect of immobilized Lactobacillus casei on the evolution of flavor compounds in probiotic dry-fermented sausages during ripening.	Sidira M, Kandylis P, Kanellaki M, Kourkoutas Y	Meat Sci	10.1016/j.meatsci.2014.09.011	2014	*
Biotechnology	Free and immobilized Lactobacillus casei ATCC 393 on whey protein as starter cultures for probiotic Feta-type cheese production.	Dimitrellou D, Kandylis P, Sidira M, Koutinas AA, Kourkoutas Y	J Dairy Sci	10.3168/jds.2013-7597	2014	*
Genetics	Construction of upp deletion mutant strains of Lactobacillus casei and Lactococcus lactis based on counterselective system using temperature-sensitive plasmid.	Song L, Cui H, Tang L, Qiao X, Liu M, Jiang Y, Cui W, Li Y	J Microbiol Methods	10.1016/j.mimet.2014.04.011	2014	*
Enzymology	Effective survival of immobilized Lactobacillus casei during ripening and heat treatment of probiotic dry-fermented sausages and investigation of the microbial dynamics.	Sidira M, Karapetsas A, Galanis A, Kanellaki M, Kourkoutas Y	Meat Sci	10.1016/j.meatsci.2013.09.013	2013	*
Enzymology	16S rRNA PCR-Denaturing Gradient Gel Electrophoresis of Oral Lactobacillus casei Group and Their Phenotypic Appearances.	Piwat S, Teanpaisan R	ISRN Microbiol	10.1155/2013/342082	2013	*
Genetics	Genomic adaptation of the Lactobacillus casei group.	Toh H, Oshima K, Nakano A, Takahata M, Murakami M, Takaki T, Nishiyama H, Igimi S, Hattori M, Morita H	PLoS One	10.1371/journal.pone.0075073	2013	*
Metabolism	Growth inhibition of hepatocellular carcinoma Huh7 cells by Lactobacillus casei extract.	Han DJ, Kim JB, Park SY, Yang MG, Kim H	Yonsei Med J	10.3349/ymj.2013.54.5.1186	2013	*
Metabolism	Increase of the adhesion ability and display of a rumen fungal xylanase on the cell surface of Lactobacillus casei by using a listerial cell-wall-anchoring protein.	Hsueh HY, Yu B, Liu CT, Liu JR	J Sci Food Agric	10.1002/jsfa.6298	2013	*
Metabolism	Use of Lactobacillus acidophilus and Lactobacillus casei for a potential probiotic legume-based fermented product using pigeon pea (Cajanus cajan).	Parra K, Ferrer M, Pinero M, Barboza Y, Medina LM	J Food Prot	10.4315/0362-028X.JFP-12-138	2013	*
Phylogeny	Characterization of the Lactobacillus casei group based on the profiling of ribosomal proteins coded in S10-spc-alpha operons as observed by MALDI-TOF MS.	Sato H, Torimura M, Kitahara M, Ohkuma M, Hotta Y, Tamura H	Syst Appl Microbiol	10.1016/j.syapm.2012.08.008	2012	*
Enzymology	Stable integration and expression of heterologous genes in several lactobacilli using an integration vector constructed from the integrase and attP sequences of phage PhiAT3 isolated from Lactobacillus casei ATCC 393.	Lin CF, Lo TC, Kuo YC, Lin TH	Appl Microbiol Biotechnol	10.1007/s00253-012-4393-5	2012	*
Stress	Investigation of Shelf Life of Potency and Activity of the Lactobacilli Produced Bacteriocins Through Their Exposure to Various Physicochemical Stress Factors.	Zacharof MP, Lovitt RW	Probiotics Antimicrob Proteins	10.1007/s12602-012-9102-2	2012	*
Pathogenicity	Growth-inhibiting effects of Paeonia lactiflora root steam distillate constituents and structurally related compounds on human intestinal bacteria.	Ngan LT, Moon JK, Kim JH, Shibamoto T, Ahn YJ	World J Microbiol Biotechnol	10.1007/s11274-011-0961-6	2011	*
Phylogeny	Lactobacillus brantae sp. nov., isolated from faeces of Canada geese (Branta canadensis).	Volokhov DV, Amselle M, Beck BJ, Popham DL, Whittaker P, Wang H, Kerrigan E, Chizhikov VE	Int J Syst Evol Microbiol	10.1099/ijs.0.033852-0	2011	*
Metabolism	Effect of cellooligosaccharide or synbiotic feeding on growth performance, fecal condition and hormone concentrations in Holstein calves.	Hasunuma T, Kawashima K, Nakayama H, Murakami T, Kanagawa H, Ishii T, Akiyama K, Yasuda K, Terada F, Kushibiki S	Anim Sci J	10.1111/j.1740-0929.2010.00861.x	2011	*
Metabolism	Effect of probiotic-fermented milk administration on gastrointestinal survival of Lactobacillus casei ATCC 393 and modulation of intestinal microbial flora.	Sidira M, Galanis A, Ypsilantis P, Karapetsas A, Progaki Z, Simopoulos C, Kourkoutas Y	J Mol Microbiol Biotechnol	10.1159/000321115	2010	*
Metabolism	Expression of Lactobacillus reuteri Pg4 collagen-binding protein gene in Lactobacillus casei ATCC 393 increases its adhesion ability to Caco-2 cells.	Hsueh HY, Yueh PY, Yu B, Zhao X, Liu JR	J Agric Food Chem	10.1021/jf1035756	2010	*
Pathogenicity	The influence of some probiotic supernatants on the growth and virulence features expression of several selected enteroaggregative E. coli clinical strains.	Lazar V, Miyazaki Y, Hanawa T, Chifiriuc MC, Ditu LM, Marutescu L, Bleotu C, Kamiya S	Roum Arch Microbiol Immunol		2009	*
Pathogenicity	[Influence of cross-protection on the survival of Lactobacillus casei ATCC 393].	Xue F, Zhang J, Du G, Chen J	Wei Sheng Wu Xue Bao		2010	*
Pathogenicity	Rapid detection and identification of probiotic Lactobacillus casei ATCC 393 by multiplex PCR.	Karapetsas A, Vavoulidis E, Galanis A, Sandaltzopoulos R, Kourkoutas Y	J Mol Microbiol Biotechnol	10.1159/000308518	2010	*
Metabolism	Effect of prebiotics on viability and growth characteristics of probiotics in soymilk.	Yeo SK, Liong MT	J Sci Food Agric	10.1002/jsfa.3808	2010	*
Enzymology	Construction of recombinant Lactobacillus casei strains using splicing by overlap extension.	Jeong DW, Lee JH, Lee HJ	J Microbiol Biotechnol	8152	2008	*
Pathogenicity	Antibacterial effects of three experimental quaternary ammonium salt (QAS) monomers on bacteria associated with oral infections.	Xiao YH, Chen JH, Fang M, Xing XD, Wang H, Wang YJ, Li F	J Oral Sci	10.2334/josnusd.50.323	2008	*
Phylogeny	The type strain of Lactobacillus casei is ATCC 393, ATCC 334 cannot serve as the type because it represents a different taxon, the name Lactobacillus paracasei and its subspecies names are not rejected and the revival of the name 'Lactobacillus zeae' contravenes Rules 51b (1) and (2) of the International Code of Nomenclature of Bacteria. Opinion 82.		Int J Syst Evol Microbiol	10.1099/ijs.0.2008/005330-0	2008	*
Pathogenicity	Fluoride release and antibacterial activity of selected dental materials.	Marczuk-Kolada G, Jakoniuk P, Mystkowska J, Luczaj-Cepowicz E, Waszkiel D, Dabrowski JR, Leszczynska K	Postepy Hig Med Dosw (Online)	453293	2006	*
Phylogeny	Taxonomic and strain-specific identification of the probiotic strain Lactobacillus rhamnosus 35 within the Lactobacillus casei group.	Coudeyras S, Marchandin H, Fajon C, Forestier C	Appl Environ Microbiol	10.1128/AEM.02286-07	2008	*
Pathogenicity	Incorporation of citrus fibers in fermented milk containing probiotic bacteria.	Sendra E, Fayos P, Lario Y, Fernandez-Lopez J, Sayas-Barbera E, Perez-Alvarez JA	Food Microbiol	10.1016/j.fm.2007.09.003	2007	*
Metabolism	Induction of immune responses in mice after intragastric administration of Lactobacillus casei producing porcine parvovirus VP2 protein.	Xu Y, Li Y	Appl Environ Microbiol	10.1128/AEM.00436-07	2007	*
Phylogeny	Multilocus sequence typing of Lactobacillus casei reveals a clonal population structure with low levels of homologous recombination.	Diancourt L, Passet V, Chervaux C, Garault P, Smokvina T, Brisse S	Appl Environ Microbiol	10.1128/AEM.01095-07	2007	*
Metabolism	Arsenic removal by native and chemically modified lactic acid bacteria.	Halttunen T, Finell M, Salminen S	Int J Food Microbiol	10.1016/j.ijfoodmicro.2007.06.002	2007	*
Pathogenicity	Antibacterial activities of inorganic agents on six bacteria associated with oral infections by two susceptibility tests.	Fang M, Chen JH, Xu XL, Yang PH, Hildebrand HF	Int J Antimicrob Agents	10.1016/j.ijantimicag.2006.01.008	2006	*
Pathogenicity	Effects of Lactobacillus strains on cancer cell proliferation and oxidative stress in vitro.	Choi SS, Kim Y, Han KS, You S, Oh S, Kim SH	Lett Appl Microbiol	10.1111/j.1472-765X.2006.01913.x	2006	*
Phylogeny	Ribotyping of Lactobacillus casei group strains isolated from dairy products.	Svec P, Drab V, Sedlacek I	Folia Microbiol (Praha)	10.1007/BF02931570	2005	*
Phylogeny	DNA-based classification and sequence heterogeneities in the 16S rRNA genes of Lactobacillus casei/paracasei and related species.	Vasquez A, Molin G, Pettersson B, Antonsson M, Ahrne S	Syst Appl Microbiol	10.1016/j.syapm.2005.02.011	2005	*
Genetics	Complete genomic sequence of the temperate bacteriophage PhiAT3 isolated from Lactobacillus casei ATCC 393.	Lo TC, Shih TC, Lin CF, Chen HW, Lin TH	Virology	10.1016/j.virol.2005.05.022	2005	*
Metabolism	Malolactic fermentation in wine with Lactobacillus casei cells immobilized on Delignified cellulosic material.	Agouridis N, Bekatorou A, Nigam P, Kanellaki M	J Agric Food Chem	10.1021/jf048736t	2005	*
Enzymology	Cell wall modifications during osmotic stress in Lactobacillus casei.	Piuri M, Sanchez-Rivas C, Ruzal SM	J Appl Microbiol	10.1111/j.1365-2672.2004.02428.x	2005	*
Phylogeny	Lactobacillus casei, Lactobacillus rhamnosus, and Lactobacillus zeae isolates identified by sequence signature and immunoblot phenotype.	Dobson CM, Chaban B, Deneer H, Ziola B	Can J Microbiol	10.1139/w04-044	2004	*
Biotechnology	Nisin-controlled expression of Norwalk virus VP60 protein in Lactobacillus casei.	Martin MC, Fernandez M, Martin-Alonso JM, Parra F, Boga JA, Alvarez MA	FEMS Microbiol Lett	10.1016/j.femsle.2004.07.002	2004	*
Cultivation	Osmotic response in Lactobacillus casei ATCC 393: biochemical and biophysical characteristics of membrane.	Machado MC, Lopez CS, Heras H, Rivas EA	Arch Biochem Biophys	10.1016/j.abb.2003.11.001	2004	*
Genetics	Homology modeling of the central catalytic domain of insertion sequence ISLC3 isolated from Lactobacillus casei ATCC 393.	Lin TH, Tsai KC, Lo TC	Protein Eng	10.1093/protein/gzg107	2003	*
Phylogeny	Significant differences between Lactobacillus casei subsp. casei ATCC 393T and a commonly used plasmid-cured derivative revealed by a polyphasic study.	Acedo-Felix E, Perez-Martinez G	Int J Syst Evol Microbiol	10.1099/ijs.0.02325-0	2003	*
Phylogeny	The status of the species Lactobacillus casei (Orla-Jensen 1916) Hansen and Lessel 1971 and Lactobacillus paracasei Collins et al. 1989. Request for an opinion.	Dellaglio F, Felis GE, Torriani S	Int J Syst Evol Microbiol	10.1099/00207713-52-1-285	2002	*
Phylogeny	Comparative sequence analysis of a recA gene fragment brings new evidence for a change in the taxonomy of the Lactobacillus casei group.	Felis GE, Dellaglio F, Mizzi L, Torriani S	Int J Syst Evol Microbiol	10.1099/00207713-51-6-2113	2001	*
Phylogeny	Characterization of the Lactobacillus casei group and the Lactobacillus acidophilus group by automated ribotyping.	Ryu CS, Czajka JW, Sakamoto M, Benno Y	Microbiol Immunol	10.1111/j.1348-0421.2001.tb02618.x	2001	*
Metabolism	Expression of cbsA encoding the collagen-binding S-protein of Lactobacillus crispatus JCM5810 in Lactobacillus casei ATCC 393(T).	Martinez B, Sillanpaa J, Smit E, Korhonen TK, Pouwels PH	J Bacteriol	10.1128/JB.182.23.6857-6861.2000	2000	*
Biotechnology	Generation of food-grade recombinant lactic acid bacterium strains by site-specific recombination.	Martin MC, Alonso JC, Suarez JE, Alvarez MA	Appl Environ Microbiol	10.1128/AEM.66.6.2599-2604.2000	2000	*
Phylogeny	Comparative analysis of the genes encoding 23S-5S rRNA intergenic spacer regions of Lactobacillus casei-related strains.	Chen H, Lim CK, Lee YK, Chan YN	Int J Syst Evol Microbiol	10.1099/00207713-50-2-471	2000	*
Metabolism	Genetics of L-sorbose transport and metabolism in Lactobacillus casei.	Yebra MJ, Veyrat A, Santos MA, Perez-Martinez G	J Bacteriol	10.1128/JB.182.1.155-163.2000	2000	*
Metabolism	Enhanced production of L-(+)-lactic acid in chemostat by Lactobacillus casei DSM 20011 using ion-exchange resins and cross-flow filtration in a fully automated pilot plant controlled via NIR.	Gonzalez-Vara Y R A, Vaccari G, Dosi E, Trilli A, Rossi M, Matteuzzi D	Biotechnol Bioeng	10.1002/(SICI)1097-0290(20000120)67:2<147::AID-BIT4>3.0.CO;2-F	2000	*
Phylogeny	Comparison of ribotyping, randomly amplified polymorphic DNA analysis, and pulsed-field gel electrophoresis in typing of Lactobacillus rhamnosus and L. casei strains.	Tynkkynen S, Satokari R, Saarela M, Mattila-Sandholm T, Saxelin M	Appl Environ Microbiol	10.1128/AEM.65.9.3908-3914.1999	1999	*
Enzymology	Transport of D-xylose in Lactobacillus pentosus, Lactobacillus casei, and Lactobacillus plantarum: evidence for a mechanism of facilitated diffusion via the phosphoenolpyruvate:mannose phosphotransferase system.	Chaillou S, Pouwels PH, Postma PW	J Bacteriol	10.1128/JB.181.16.4768-4773.1999	1999	*
Metabolism	Elements involved in catabolite repression and substrate induction of the lactose operon in Lactobacillus casei.	Gosalbes MJ, Monedero V, Perez-Martinez G	J Bacteriol	10.1128/JB.181.13.3928-3934.1999	1999	*
Biotechnology	Stable expression of the Lactobacillus casei bacteriophage A2 repressor blocks phage propagation during milk fermentation.	Alvarez MA, Rodriguez A, Suarez JE	J Appl Microbiol	10.1046/j.1365-2672.1999.00728.x	1999	*
Enzymology	Catabolite repression in Lactobacillus casei ATCC 393 is mediated by CcpA.	Monedero V, Gosalbes MJ, Perez-Martinez G	J Bacteriol	10.1128/jb.179.21.6657-6664.1997	1997	*
Metabolism	Peptidoglycan structure of Lactobacillus casei, a species highly resistant to glycopeptide antibiotics.	Billot-Klein D, Legrand R, Schoot B, van Heijenoort J, Gutmann L	J Bacteriol	10.1128/jb.179.19.6208-6212.1997	1997	*
Genetics	Establishing a model to study the regulation of the lactose operon in Lactobacillus casei.	Gosalbes MJ, Monedero V, Alpert CA, Perez-Martinez G	FEMS Microbiol Lett	10.1111/j.1574-6968.1997.tb10271.x	1997	*
Phylogeny	Reclassification of Lactobacillus casei subsp. casei ATCC 393 and Lactobacillus rhamnosus ATCC 15820 as Lactobacillus zeae nom. rev., designation of ATCC 334 as the neotype of L. casei subsp. casei, and rejection of the name Lactobacillus paracasei.	Dicks LM, Du Plessis EM, Dellaglio F, Lauer E	Int J Syst Bacteriol	10.1099/00207713-46-1-337	1996	*
Enzymology	Expression of Lactobacillus casei ATCC 393 beta-galactosidase encoded by plasmid pLZ15 in Lactococcus lactis CNRZ 1123.	Hemme D, Gaier W, Winters DA, Foucaud C, Vogel RF	Lett Appl Microbiol	10.1111/j.1472-765x.1994.tb00471.x	1994	*
Metabolism	Glucose transport by the phosphoenolpyruvate:mannose phosphotransferase system in Lactobacillus casei ATCC 393 and its role in carbon catabolite repression.	Veyrat A, Monedero V, Perez-Martinez G	Microbiology (Reading)	10.1099/13500872-140-5-1141	1994	*
Genetics	Structural and functional analysis of two cryptic plasmids from Lactobacillus pentosus MD353 and Lactobacillus plantarum ATCC 8014.	Leer RJ, van Luijk N, Posno M, Pouwels PH	Mol Gen Genet	10.1007/BF00283847	1992	*
Enzymology	Cloning and nucleotide sequence of the Lactobacillus casei lactate dehydrogenase gene.	Kim SF, Baek SJ, Pack MY	Appl Environ Microbiol	10.1128/aem.57.8.2413-2417.1991	1991	*
Cultivation	Microbial caries induction in the roots of human teeth in vitro.	Kaufman HW, Pollock JJ, Gwinnett AJ	Arch Oral Biol	10.1016/0003-9969(88)90031-3	1988	*
Enzymology	Proteolytic activity of crude cell-free extract of Lactobacillus casei and Lactobacillus plantarum.	Hegazi FZ, Abo-Elnaga IG	Nahrung	10.1002/food.19870310309	1987	*
Enzymology	Comparative studies of lactic acid dehydrogenases in lactic acid bacteria. I. Purification and kinetics of the allosteric L-lactic acid dehydrogenase from Lactobacillus casei ssp. casei and Lactobacillus curvatus.	Hensel R, Mayr U, Stetter KO, Kandler O	Arch Microbiol	10.1007/BF00446658	1977	*
Enzymology	Purification, properties and immunological relationship of L (+)-lactate dehydrogenase from Lactobacillus casei.	Gordon GL, Doelle HW	Eur J Biochem	10.1111/j.1432-1033.1976.tb10720.x	1976	*
Metabolism	Effects of citrate on the composition and metabolism of Lactobacillus casei.	Branen AL, Keenan TW	Appl Microbiol	10.1128/am.21.6.993-998.1971	1971	*
Metabolism	Dietary supplementation with selenium nanoparticles-enriched Lactobacillus casei ATCC 393 alleviates intestinal barrier dysfunction of mice exposed to deoxynivalenol by regulating endoplasmic reticulum stress and gut microbiota.	Song X, Qiao L, Chang J, Dou X, Zhang X, Pi S, Xu C	Ecotoxicol Environ Saf	10.1016/j.ecoenv.2022.114276	2022	*
Metabolism	Selenium Nanoparticles-Enriched Lactobacillus casei ATCC 393 Prevents Cognitive Dysfunction in Mice Through Modulating Microbiota-Gut-Brain Axis.	Qiao L, Chen Y, Song X, Dou X, Xu C	Int J Nanomedicine	10.2147/IJN.S374024	2022	*
	Evaluation of the Immunogenicity in Mice Orally Immunized with Recombinant Lactobacillus casei Expressing Porcine Epidemic Diarrhea Virus S1 Protein.	Xiao Y, Wang X, Li Y, Li F, Zhao H, Shao Y, Zhang L, Ding G, Li J, Jiang Y, Cui W, Shan Z, Zhou H, Wang L, Qiao X, Tang L, Li Y	Viruses	10.3390/v14050890	2022	*
	Antiparasitic Action of Lactobacillus casei ATCC 393 and Lactobacillus paracasei CNCM Strains in CD-1 Mice Experimentally Infected with Trichinella britovi.	Boros Z, Baies MH, Vodnar DC, Gherman CM, Borsan SD, Cozma-Petrut A, Lefkaditis M, Gyorke A, Cozma V	Pathogens	10.3390/pathogens11030296	2022	*
	Lacticaseibacillus casei ATCC 393 Cannot Colonize the Gastrointestinal Tract of Crucian Carp.	Zhang H, Mu X, Wang H, Wang H, Wang H, Li Y, Mu Y, Song J, Xia L	Microorganisms	10.3390/microorganisms9122547	2021	*
	Polymer and Crosslinker Content Influences Performance of Encapsulated Live Biotherapeutic Products.	Qiu K, Huang Y, Anselmo AC	Cell Mol Bioeng	10.1007/s12195-021-00674-z	2021	*
	Anticancer Activity of Biogenic Selenium Nanoparticles: Apoptotic and Immunogenic Cell Death Markers in Colon Cancer Cells.	Spyridopoulou K, Aindelis G, Pappa A, Chlichlia K	Cancers (Basel)	10.3390/cancers13215335	2021	*
	Alterations in Faecal Microbiota and Elevated Levels of Intestinal IgA Following Oral Administration of Lacticaseibacillus casei in mice.	Aindelis G, Ypsilantis P, Chlichlia K	Probiotics Antimicrob Proteins	10.1007/s12602-021-09864-7	2021	*
	Development and Optimization of Djulis Sourdough Bread Fermented by Lactic Acid Bacteria for Antioxidant Capacity.	Chen HY, Hsieh CW, Chen PC, Lin SP, Lin YF, Cheng KC	Molecules	10.3390/molecules26185658	2021	*
	Oral Immunization with Lactobacillus casei Expressing the Porcine Circovirus Type 2 Cap and LTB Induces Mucosal and Systemic Antibody Responses in Mice.	Li F, Wang X, Ma R, Wu W, Teng F, Cheng X, Jiang Y, Zhou H, Wang L, Tang L, Qiao X, Li Y	Viruses	10.3390/v13071302	2021	*
	Encapsulation of Lactobacillus in Low-Methoxyl Pectin-Based Microcapsules Stimulates Biofilm Formation: Enhanced Resistances to Heat Shock and Simulated Gastrointestinal Digestion.	He C, Sampers I, Van de Walle D, Dewettinck K, Raes K	J Agric Food Chem	10.1021/acs.jafc.1c00719	2021	*
	Microencapsulation of Lactobacillus casei and Lactobacillus rhamnosus in pectin and pectin-inulin microgel particles: Effect on bacterial survival under storage conditions.	Tarifa MC, Piqueras CM, Genovese DB, Brugnoni LI	Int J Biol Macromol	10.1016/j.ijbiomac.2021.03.038	2021	*
	Polymeric Films for the Encapsulation, Storage, and Tunable Release of Therapeutic Microbes.	Qiu K, Young I, Woodburn BM, Huang Y, Anselmo AC	Adv Healthc Mater	10.1002/adhm.201901643	2020	*
	Enhanced Aromatic Profile and Functionality of Cheese Whey Beverages by Incorporation of Probiotic Cells Immobilized on Pistacia terebinthus Resin.	Schoina V, Terpou A, Papadaki A, Bosnea L, Kopsahelis N, Kanellaki M	Foods	10.3390/foods9010013	2019	*
	Assessment of Freeze-Dried Immobilized Lactobacillus casei as Probiotic Adjunct Culture in Yogurts.	Dimitrellou D, Kandylis P, Kourkoutas Y	Foods	10.3390/foods8090374	2019	*
	Effect of Milk Type on the Microbiological, Physicochemical and Sensory Characteristics of Probiotic Fermented Milk.	Dimitrellou D, Salamoura C, Kontogianni A, Katsipi D, Kandylis P, Zakynthinos G, Varzakas T	Microorganisms	10.3390/microorganisms7090274	2019	*
	Recombinant l-Asparaginase II from Lactobacillus casei subsp. casei ATCC 393 and Its Anticancer Activity.	Aishwarya SS, Selvarajan E, Iyappan S, Rajnish KN	Indian J Microbiol	10.1007/s12088-019-00806-0	2019	*
	Effect of Sugar Content on Quality Characteristics and Shelf-Life of Probiotic Dry-Fermented Sausages Produced by Free or Immobilized Lactobacillus casei ATCC 393.	Sidira M, Mitropoulou G, Galanis A, Kanellaki M, Kourkoutas Y	Foods	10.3390/foods8060219	2019	*
	Genetic Signatures of Dairy Lactobacillus casei Group.	Fontana A, Zacconi C, Morelli L	Front Microbiol	10.3389/fmicb.2018.02611	2018	*
	Biogenic Synthesis of Novel Functionalized Selenium Nanoparticles by Lactobacillus casei ATCC 393 and Its Protective Effects on Intestinal Barrier Dysfunction Caused by Enterotoxigenic Escherichia coli K88.	Xu C, Guo Y, Qiao L, Ma L, Cheng Y, Roman A	Front Microbiol	10.3389/fmicb.2018.01129	2018	*
	Soybean protein-based microparticles for oral delivery of probiotics with improved stability during storage and gut resistance.	Gonzalez-Ferrero C, Irache JM, Gonzalez-Navarro CJ	Food Chem	10.1016/j.foodchem.2017.07.022	2017	*
	Directed chromosomal integration and expression of porcine rotavirus outer capsid protein VP4 in Lactobacillus casei ATCC393.	Yin JY, Guo CQ, Wang Z, Yu ML, Gao S, Bukhari SM, Tang LJ, Xu YG, Li YJ	Appl Microbiol Biotechnol	10.1007/s00253-016-7779-y	2016	*
	Orally Administered Salacia reticulata Extract Reduces H1N1 Influenza Clinical Symptoms in Murine Lung Tissues Putatively Due to Enhanced Natural Killer Cell Activity.	Romero-Perez GA, Egashira M, Harada Y, Tsuruta T, Oda Y, Ueda F, Tsukahara T, Tsukamoto Y, Inoue R	Front Immunol	10.3389/fimmu.2016.00115	2016	*
	Effect of curing salts and probiotic cultures on the evolution of flavor compounds in dry-fermented sausages during ripening.	Sidira M, Kandylis P, Kanellaki M, Kourkoutas Y	Food Chem	10.1016/j.foodchem.2016.01.084	2016	*
	In vitro study on the cell adhesion ability of immobilized lactobacilli on natural supports.	Sidira M, Kourkoutas Y, Kanellaki M, Charalampopoulos D	Food Res Int	10.1016/j.foodres.2015.07.036	2015	*
	Use of Pistacia terebinthus resin as immobilization support for Lactobacillus casei cells and application in selected dairy products.	Schoina V, Terpou A, Angelika-Ioanna G, Koutinas A, Kanellaki M, Bosnea L	J Food Sci Technol	10.1007/s13197-014-1627-9	2014	*
	Chromosomal insertions in the Lactobacillus casei upp gene that are useful for vaccine expression.	Song BF, Ju LZ, Li YJ, Tang LJ	Appl Environ Microbiol	10.1128/AEM.00175-14	2014	*
	Monitoring survival of Lactobacillus casei ATCC 393 in probiotic yogurts using an efficient molecular tool.	Sidira M, Saxami G, Dimitrellou D, Santarmaki V, Galanis A, Kourkoutas Y	J Dairy Sci	10.3168/jds.2012-6343	2013	*
	The effects of microencapsulated Lactobacillus casei on tumour cell growth: In vitro and in vivo studies.	Dwivedi A, Nomikou N, Nigam PS, McHale AP	Int J Med Microbiol	10.1016/j.ijmm.2012.09.002	2012	*
	Distinct adhesion of probiotic strain Lactobacillus casei ATCC 393 to rat intestinal mucosa.	Saxami G, Ypsilantis P, Sidira M, Simopoulos C, Kourkoutas Y, Galanis A	Anaerobe	10.1016/j.anaerobe.2012.04.002	2012	*
	Microencapsulation of a probiotic bacteria with alginate-gelatin and its properties.	Li XY, Chen XG, Cha DS, Park HJ, Liu CS	J Microencapsul	10.1080/02652040802328685	2008	*
	Construction of recombinant Lactobacillus casei efficiently surface displayed and secreted porcine parvovirus VP2 protein and comparison of the immune responses induced by oral immunization.	Yigang XU, Yijing LI	Immunology	10.1111/j.1365-2567.2007.02738.x	2007	*
	Impact of lactic Acid bacteria on dendritic cells from allergic patients in an experimental model of intestinal epithelium.	Ratajczak C, Duez C, Grangette C, Pochard P, Tonnel AB, Pestel J	J Biomed Biotechnol	10.1155/2007/71921	2007	*
	Biogenic Selenium Nanoparticles Synthesized by Lactobacillus casei ATCC 393 Alleviate Acute Hypobaric Hypoxia-Induced Intestinal Barrier Dysfunction in C57BL/6 Mice.	Dou X, Zhang B, Qiao L, Song X, Pi S, Chang J, Zhang X, Zeng X, Zhu L, Xu C	Biol Trace Elem Res	10.1007/s12011-022-03513-y	2022	*
	Biogenic Selenium Nanoparticles Attenuate Abeta(25-35)-Induced Toxicity in PC12 Cells via Akt/CREB/BDNF Signaling Pathway.	Qiao L, Chen Y, Dou X, Song X, Xu C	Neurotox Res	10.1007/s12640-022-00590-8	2022	*
	Biogenic selenium nanoparticles produced by Lactobacillus casei ATCC 393 inhibit colon cancer cell growth in vitro and in vivo.	Spyridopoulou K, Tryfonopoulou E, Aindelis G, Ypsilantis P, Sarafidis C, Kalogirou O, Chlichlia K	Nanoscale Adv	10.1039/d0na00984a	2021	*

References

#8425

Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 20011

#20215

Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 )

#20218

Verslyppe, B., De Smet, W., De Baets, B., De Vos, P., Dawyndt P.: StrainInfo introduces electronic passports for microorganisms.. Syst Appl Microbiol. 37: 42 - 50 2014 ( DOI 10.1016/j.syapm.2013.11.002 , PubMed 24321274 )

#22930

Evelia Acedo-Félix, Gaspar Pérez-Martínez: Significant differences between Lactobacillus casei subsp. casei ATCC 393T and a commonly used plasmid-cured derivative revealed by a polyphasic study. IJSEM 53: 67 - 75 2003 ( DOI 10.1099/ijs.0.02325-0 , PubMed 12656154 )

#41833 ; Curators of the CIP;
#47412 Culture Collection University of Gothenburg (CCUG) ; Curators of the CCUG; CCUG 21451

#66792

Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) .

#67770 Japan Collection of Microorganism (JCM) ; Curators of the JCM;

#68371

Automatically annotated from API 50CH acid .

#68379

Automatically annotated from API Coryne .

#68382

Automatically annotated from API zym .

#69479

João F Matias Rodrigues, Janko Tackmann,Gregor Rot, Thomas SB Schmidt, Lukas Malfertheiner, Mihai Danaila,Marija Dmitrijeva, Daniela Gaio, Nicolas Näpflin and Christian von Mering. University of Zurich.: MicrobeAtlas 1.0 beta .

#69480

Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Predictions based on genome sequence made in the Diaspora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) .

#69481

Xiao-Yin To, René Mreches, Martin Binder, Alice C. McHardy, Philipp C. Münch: Predictions based on the model GenomeNet Sporulation v. 1 . ( DOI 10.21203/rs.3.rs-2527258/v1 )

#76030

Reimer, L.C., Lissin, A.,Schober, I., Witte,J.F., Podstawka, A., Lüken, H., Bunk, B.,Overmann, J.: StrainInfo: A central database for resolving microbial strain identifiers . ( DOI 10.60712/SI-ID9751.1 )

#117199 Collection of Institut Pasteur ; Curators of the CIP; CIP 103137
* These data were automatically processed and therefore are not curated

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Lacticaseibacillus casei DSM 20011 = JCM 1134 = ATCC 393 ATCC 393

Lacticaseibacillus casei DSM 20011 = JCM 1134 = ATCC 393 ATCC 393

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