Lacticaseibacillus casei (CCUG 21451, IAM 12473, LMG 6904)

Name: Lacticaseibacillus casei (CCUG 21451, IAM 12473, LMG 6904)
Creator: BacDive
License: http://creativecommons.org/licenses/by/4.0/

BacDive ID 6559

Type strain

Strain Designation 03, 7, O3

Culture col. no. CCUG 21451 IAM 12473 LMG 6904 DSM 20011 ATCC 393 18 more

NCBI tax ID(s) 1582

Special Collections DSMZ CCUG JCM KCTC CIP Literature strains

Links

Lacticaseibacillus casei 03 is a facultative anaerobe, Gram-positive, rod-shaped prokaryote that was isolated from cheese.

Gram-positive rod-shaped facultative anaerobe genome sequence 16S sequence

Name and taxonomic classification

SI-ID 9751

LMG 9190,ATCC 393,CECT 475,DSM 20011,IAM 12473,JCM 1134,LMG 6904,NCFB 161,NCIMB 11970,NBIMCC 3485,CCUG 21451,NCDO 161,CIP 103137,NCIB 11970,CCRC 10697,IFO 15883,KCTC 3109,HAMBI 85,VTT E-85225,CECT 5275,NRRL B-1922,KCTC 3110,NBRC 15883,CCM 7088,BCC 4308,BCRC 10697,CCT 3750,CCT 1465,CDBB 794,CDBB 382,BCRC 17646,CCRC 17646,VTT E-001744,VTT E-001745

@ref 20215

Last LPSN update 2025-12-16 09:48:21

Domain Bacillati

Phylum Bacillota

Class Bacilli

Order Lactobacillales

Family Lactobacillaceae

Genus Lacticaseibacillus

Species Lacticaseibacillus casei

Full scientific name Lacticaseibacillus casei (Orla-Jensen 1916) Zheng et al. 2020

Synonyms (2)

"Caseobacterium vulgare"
Lactobacillus casei

BacDive ID	Other strains from **Lacticaseibacillus casei** (10)	Type strain
137569	L. casei pLZ15, CIP 109805
162697	L. casei JCM 20024, ATU L-29, IAM 1045
162859	L. casei JCM 20304, IAM 10062
163108	L. casei JCM 2120, ATCC 4913
165741	L. casei JCM 8129, BCRC 17487, NCDO 173
165853	L. casei JCM 8608
165859	L. casei JCM 8615
165865	L. casei JCM 8621
165892	L. casei JCM 8648
165915	L. casei JCM 8677

Morphology

Cell morphology

@ref	Gram stain	Cell shape	Confidence
117199	positive	rod-shaped
125438			91
125438	positive		92.55

Culture and growth conditions

Culture medium

@ref	Name	Medium link	Composition
8425	MRS MEDIUM (DSMZ Medium 11)	Medium recipe at MediaDive	Name: MRS MEDIUM (DSMZ Medium 11) Composition: Glucose 20.0 g/l Casein peptone 10.0 g/l Meat extract 10.0 g/l Na-acetate 5.0 g/l Yeast extract 5.0 g/l (NH4)3 citrate 2.0 g/l K2HPO4 2.0 g/l Tween 80 1.0 g/l MgSO4 x 7 H2O 0.2 g/l MnSO4 x H2O 0.05 g/l Distilled water
41833	MEDIUM 40- for Lactobacillus and Leuconostoc		Distilled water make up to (1000.000 ml);Man Rogosa Sharp agar (68.000 g)
117199	CIP Medium 40	Medium recipe at CIP

Culture temp

@ref	Growth	Type	Temperature (°C)	Range
8425	positive	growth	30	mesophilic
22930	positive	growth	15-45
41833	positive	growth	37	mesophilic
67770	positive	growth	37	mesophilic
117199	positive	growth	15-45
117199	negative	growth	10

Physiology and metabolism

Oxygen tolerance

@ref	Oxygen tolerance	Confidence
117199	facultative anaerobe
125439	microaerophile	98.4

Spore formation

@ref	Spore formation	Confidence
117199
125439		90.2

Compound production

@ref	Compound
8425	acetoin
8425	diacetyl

Murein

@ref	Murein short key	Type
8425	A11.31	A4alpha L-Lys-D-Asp

Metabolite utilization

@ref	Chebi-ID	Metabolite	Utilization activity	Kind of utilization tested
22930	27613 ChEBI	amygdalin	+	growth
68371	27613 ChEBI	amygdalin	+	builds acid from	from API 50CH acid
68371	18305 ChEBI	arbutin	+	builds acid from	from API 50CH acid
68371	17057 ChEBI	cellobiose	+	builds acid from	from API 50CH acid
68371	17108 ChEBI	D-arabinose	-	builds acid from	from API 50CH acid
68371	18333 ChEBI	D-arabitol	-	builds acid from	from API 50CH acid
68371	15824 ChEBI	D-fructose	+	builds acid from	from API 50CH acid
68371	28847 ChEBI	D-fucose	-	builds acid from	from API 50CH acid
68371	12936 ChEBI	D-galactose	+	builds acid from	from API 50CH acid
68371	17634 ChEBI	D-glucose	+	builds acid from	from API 50CH acid
22930	62318 ChEBI	D-lyxose	-	growth
68371	62318 ChEBI	D-lyxose	-	builds acid from	from API 50CH acid
68379	16899 ChEBI	D-mannitol	+	fermentation	from API Coryne
68371	16899 ChEBI	D-mannitol	+	builds acid from	from API 50CH acid
68371	16024 ChEBI	D-mannose	+	builds acid from	from API 50CH acid
68379	16988 ChEBI	D-ribose	-	fermentation	from API Coryne
68371	16988 ChEBI	D-ribose	-	builds acid from	from API 50CH acid
68371	17924 ChEBI	D-sorbitol	-	builds acid from	from API 50CH acid
68379	65327 ChEBI	D-xylose	-	fermentation	from API Coryne
68371	65327 ChEBI	D-xylose	-	builds acid from	from API 50CH acid
68371	17113 ChEBI	erythritol	-	builds acid from	from API 50CH acid
68379	4853 ChEBI	esculin	+	hydrolysis	from API Coryne
68371	4853 ChEBI	esculin	+	builds acid from	from API 50CH acid
68371	16813 ChEBI	galactitol	-	builds acid from	from API 50CH acid
68379	5291 ChEBI	gelatin	-	hydrolysis	from API Coryne
68371	17754 ChEBI	glycerol	-	builds acid from	from API 50CH acid
68379	28087 ChEBI	glycogen	-	fermentation	from API Coryne
68371	28087 ChEBI	glycogen	-	builds acid from	from API 50CH acid
68371	15443 ChEBI	inulin	-	builds acid from	from API 50CH acid
68371	30849 ChEBI	L-arabinose	-	builds acid from	from API 50CH acid
68371	18403 ChEBI	L-arabitol	-	builds acid from	from API 50CH acid
68371	18287 ChEBI	L-fucose	-	builds acid from	from API 50CH acid
68371	62345 ChEBI	L-rhamnose	-	builds acid from	from API 50CH acid
22930	17266 ChEBI	L-sorbose	-	growth
68371	17266 ChEBI	L-sorbose	-	builds acid from	from API 50CH acid
68371	65328 ChEBI	L-xylose	-	builds acid from	from API 50CH acid
68379	17716 ChEBI	lactose	+	fermentation	from API Coryne
68371	17716 ChEBI	lactose	+	builds acid from	from API 50CH acid
68379	17306 ChEBI	maltose	+	fermentation	from API Coryne
68371	17306 ChEBI	maltose	-	builds acid from	from API 50CH acid
22930	6731 ChEBI	melezitose	+	growth
68371	6731 ChEBI	melezitose	+	builds acid from	from API 50CH acid
68371	28053 ChEBI	melibiose	-	builds acid from	from API 50CH acid
68371	320061 ChEBI	methyl alpha-D-glucopyranoside	-	builds acid from	from API 50CH acid
68371	43943 ChEBI	methyl alpha-D-mannoside	-	builds acid from	from API 50CH acid
68371	74863 ChEBI	methyl beta-D-xylopyranoside	-	builds acid from	from API 50CH acid
68371	17268 ChEBI	myo-inositol	-	builds acid from	from API 50CH acid
68371	59640 ChEBI	N-acetylglucosamine	+	builds acid from	from API 50CH acid
68379	17632 ChEBI	nitrate	+	reduction	from API Coryne
117199	17632 ChEBI	nitrate	-	reduction
117199	17632 ChEBI	nitrate	+	respiration
117199	16301 ChEBI	nitrite	-	reduction
68371		Potassium 2-ketogluconate	-	builds acid from	from API 50CH acid
68371		Potassium 5-ketogluconate	-	builds acid from	from API 50CH acid
68371	16634 ChEBI	raffinose	-	builds acid from	from API 50CH acid
22930	15963 ChEBI	ribitol	-	growth
68371	15963 ChEBI	ribitol	-	builds acid from	from API 50CH acid
22930	33942 ChEBI	ribose	-	growth
68371	17814 ChEBI	salicin	+	builds acid from	from API 50CH acid
22930	30911 ChEBI	sorbitol	-	growth
68371	28017 ChEBI	starch	-	builds acid from	from API 50CH acid
22930	17992 ChEBI	sucrose	-	growth
68379	17992 ChEBI	sucrose	+	fermentation	from API Coryne
68371	27082 ChEBI	trehalose	+	builds acid from	from API 50CH acid
22930	32528 ChEBI	turanose	-	growth
68371	32528 ChEBI	turanose	-	builds acid from	from API 50CH acid
68379	16199 ChEBI	urea	-	hydrolysis	from API Coryne
68371	17151 ChEBI	xylitol	-	builds acid from	from API 50CH acid

Metabolite tests

@ref	Chebi-ID	Metabolite	Voges-proskauer-test
117199	15688 ChEBI	acetoin	+

Enzymes

@ref	Value	Activity	Ec
68382	acid phosphatase	+	3.1.3.2	from API zym
117199	alcohol dehydrogenase	-	1.1.1.1
68382	alkaline phosphatase	+	3.1.3.1	from API zym
68379	alkaline phosphatase	+	3.1.3.1	from API Coryne
68382	alpha-chymotrypsin	+	3.4.21.1	from API zym
68382	alpha-fucosidase	-	3.2.1.51	from API zym
68382	alpha-galactosidase	-	3.2.1.22	from API zym
68382	alpha-glucosidase	-	3.2.1.20	from API zym
68379	alpha-glucosidase	-	3.2.1.20	from API Coryne
68382	alpha-mannosidase	-	3.2.1.24	from API zym
68382	beta-galactosidase	+	3.2.1.23	from API zym
68379	beta-galactosidase	+	3.2.1.23	from API Coryne
68382	beta-glucosidase	+	3.2.1.21	from API zym
68379	beta-glucosidase	+	3.2.1.21	from API Coryne
68382	beta-glucuronidase	-	3.2.1.31	from API zym
68379	beta-glucuronidase	-	3.2.1.31	from API Coryne
117199	catalase	-	1.11.1.6
68379	catalase	+	1.11.1.6	from API Coryne
68382	cystine arylamidase	+	3.4.11.3	from API zym
68382	esterase (C 4)	+		from API zym
68382	esterase lipase (C 8)	+		from API zym
68379	gelatinase	-		from API Coryne
68382	leucine arylamidase	+	3.4.11.1	from API zym
68382	lipase (C 14)	+		from API zym
117199	lysine decarboxylase	-	4.1.1.18
68382	N-acetyl-beta-glucosaminidase	-	3.2.1.52	from API zym
68379	N-acetyl-beta-glucosaminidase	-	3.2.1.52	from API Coryne
68382	naphthol-AS-BI-phosphohydrolase	+		from API zym
117199	ornithine decarboxylase	-	4.1.1.17
117199	oxidase	-
68379	pyrazinamidase	-	3.5.1.B15	from API Coryne
68379	pyrrolidonyl arylamidase	+	3.4.19.3	from API Coryne
68382	trypsin	-	3.4.21.4	from API zym
68379	urease	-	3.5.1.5	from API Coryne
68382	valine arylamidase	+		from API zym

API coryne

@ref	Reduction of nitrateNIT	PYZ	PYRA	PAL	beta GUR	beta GAL	alpha GLU	beta NAG	ESC	URE	GEL	Control fermentationControl	GLU	RIB	XYL	MAN	MAL	LAC	SAC	GLYG	CAT
47412	+	-	+	+	-	+	-	-	+	-	-	-	not determinedn.d.	-	-	+	+	+	+	-	+

API zym

@ref	Control	Alkaline phosphatase	Esterase (C 4)	2-naphtyl caprylateEsterase Lipase (C 8)	Lipase (C 14)	L-leucyl-2-naphthylamideLeucine arylamidase	L-valyl-2-naphthylamideValine arylamidase	L-cystyl-2-naphthylamideCystine arylamidase	Trypsin	alpha- Chymotrypsin	Acid phosphatase	Naphthol-AS-BI-phosphateNaphthol-AS-BI-phosphohydrolase	alpha- Galactosidase	beta- Galactosidase	beta- Glucuronidase	alpha- Glucosidase	beta- Glucosidase	N-acetyl-beta- glucosaminidase	alpha- Mannosidase	alpha- Fucosidase
117199	-	+	+	+	+	+	+	+	-	+	+	+	-	+	-	-	+	-	-	-

API 50CHac

@ref	ControlQ	GLY	ERY	DARA	LARA	RIB	DXYL	LXYL	ADO	MDX	GAL	GLU	FRU	MNE	SBE	RHA	DUL	INO	MAN	SOR	MDM	MDG	NAG	AMY	ARB	ESC	SAL	CEL	MAL	LAC	MEL	SAC	TRE	INU	MLZ	RAF	AMD	GLYG	XLT	GEN	TUR	LYX	TAG	DFUC	LFUC	DARL	LARL	GNT	2KG	5KG
8425	-	-	-	-	-	-	-	-	-	-	+	+	+	+	-	-	-	-	+	-	-	-	+	+	+	+	+	+	-	+	-	-	+	-	+	-	-	-	-	+	-	-	+	-	-	-	-	-	-	-
8425	-	-	-	-	-	-	-	-	-	-	+	+	+	+	-	-	-	-	+	-	-	-	+	+	+	+	+	+	-	+	-	-	+	-	+	-	-	-	-	+	-	-	+	-	-	-	-	-	-	-
8425	-	-	-	-	-	-	-	-	-	-	+	+	+	+	-	-	-	-	+	-	-	-	+	+	+	+	+	+	-	+	-	-	+	-	+	-	-	-	-	-	-	-	+	-	-	-	-	-	-	-
8425	-	-	-	-	-	-	-	-	-	-	+	+	+	+	-	-	-	-	+	-	-	-	+	+	+	+	+	+	-	+	-	-	+	-	+	-	-	-	-	-	-	-	+	-	-	-	-	-	-	-
8425	-	-	-	-	-	-	-	-	-	-	+	+	+	+	-	-	-	-	+	-	-	-	+	+	+	+	+	+	-	+	-	-	+	-	+	-	-	-	-	+	-	-	+	-	-	-	-	+	-	-
8425	-	-	-	-	-	-	-	-	-	-	+	+	+	+	-	-	-	-	+	-	-	-	+	+	+	+	+	+	-	+	-	-	+	-	+	-	-	-	-	+	-	-	+	-	-	-	-	+	-	-
8425	-	-	-	-	-	-	-	-	-	-	+	+	+	+	-	-	-	-	+	-	-	-	+	+	+	+	+	+	-	+	-	+/-	+	-	+	-	-	-	-	+	-	-	+	-	-	-	-	+	-	-
8425	-	-	-	-	-	-	-	-	-	-	+	+	+	+	-	-	-	-	+	-	-	-	+	+	+	+	+	+	-	+	-	-	+	-	+	-	-	-	-	+	-	-	-	-	-	-	-	+	-	-

Isolation, sampling and environmental information

Isolation source categories

Cat1	Cat2	Cat3
#Engineered	#Food production	#Dairy product

Isolation

@ref	Sample type
8425	cheese
47412	Cheese
67770	Cheese
117199	Food, Cheese

Taxonmaps

69479

Global distribution of 16S sequence LC064894 (>99% sequence identity) for Lactobacillaceae from Microbeatlas

Aquatic Samples	2397
Soil Samples	1801
Animal Samples	39363
Plant Samples	883
Total Samples	44444

Interaction and safety

Risk assessment

@ref	Pathogenicity human	Biosafety level	Biosafety level comment
8425	yes, in single cases	1	Risk group (German classification) According to TRBA 466
117199		1	Risk group (French classification) According to TRBA 466

Sequence information

Genome sequences

@ref	Description	Assembly level	INSDC accession	BV-BRC accession	IMG accession	NCBI tax ID	Score
66792	ASM82905v1 assembly for Lacticaseibacillus casei DSM 20011 = JCM 1134 = ATCC 393	complete	GCA_000829055	219334.4	2630968676	1423732	94.31
67770	ASM143373v1 assembly for Lacticaseibacillus casei DSM 20011 = JCM 1134 = ATCC 393	scaffold	GCA_001433735	1423732.4	2700989128	1423732	22.59
66792	ASM61520v1 assembly for Lacticaseibacillus casei DSM 20011 = JCM 1134 = ATCC 393	contig	GCA_000615205	1236939.3	2585427874	1423732	5.89

16S sequences

@ref	Description	Accession	Length	NCBI tax ID
20218	Lacticaseibacillus casei gene for 16S rRNA, partial sequence, strain: YIT 0078 (= ATCC 393)	AB008212	1563	57037
20218	Lactobacillus casei strain BL23 16S ribosomal RNA gene, partial sequence	AF385770	1518	543734
20218	Lactobacillus zeae ATCC 393 16S ribosomal RNA gene, partial sequence	AF429500	507	219334
20218	Lactobacillus zeae strain ATCC 393 16S ribosomal RNA gene, partial sequence; 16S-23S intergenic spacer, complete sequence; and 23S ribosomal RNA gene, partial sequence	AF429587	537	219334
20218	Lactobacillus casei strain ATCC 393 16S ribosomal RNA gene, partial sequence	AF469172	1517	219334
20218	Lactobacillus casei subsp. casei ATCC 393 16S ribosomal RNA gene, partial sequence	AY196978	518	219334
20218	L.casei small subunit ribosomal RNA	M23928	1574	1582
20218	L.casei rrn operon, 16S-23S rRNA spacer (long), tRNA-Ile and tRNA-Ala genes	Z75478	432	219334
20218	L.casei rrn operon, 16S-23S rRNA spacer (short)	Z75479	218	219334
20218	Lactobacillus casei strain BCRC10697 16S ribosomal RNA gene, complete sequence	AY773945	1528	1582
20218	Lactobacillus casei strain CECT 5275 16S ribosomal RNA gene, partial sequence	AY196967	518	1582
20218	Lactobacillus casei strain DSM 20011 16S ribosomal RNA gene, partial sequence	EF468100	619	1582
20218	Lactobacillus casei genes for 16S rRNA, 16S-23S internal transcribed spacer, tRNA-Ile, tRNA-Ala, 23S rRNA, partial and complete sequence, strain:JCM 1134	AB237516	577	219334
20218	Lactobacillus casei genes for 16S rRNA, 16S-23S internal transcribed spacer, 23S rRNA, partial sequence, strain:JCM 1134	AB237517	364	219334
20218	Lactobacillus casei gene for 16S rRNA, partial sequence, strain: JCM 1134	AB289057	681	219334
20218	Lactobacillus casei subsp. casei 16S ribosomal RNA, partial sequence; 16S/23S intergenic spacer region, complete sequence; and 23S ribosomal RNA partial sequence	AF182729	685	219334
20218	Lactobacillus casei gene for 16S rRNA	D16551	1522	219334
20218	Lactobacillus casei gene for 16S rRNA, partial sequence, strain: NBRC 15883	AB626050	1495	1582
20218	L.casei 16S rRNA gene	X61135	1491	219334
67770	Lactobacillus casei gene for 16S ribosomal RNA, partial sequence, strain: JCM 1134	LC064894	1468	1423732

GC content

@ref	GC-content (mol%)	Method
8425	49.0
67770	46.5	genome sequence analysis
67770	49

Genome-based predictions

Predictions

Predictions from Deep Learning for Genome Sequence Data. R package version 0.3.1 based on: Lactobacillus casei subsp. casei ATCC 393
PATRIC: 219334.4

@ref	Trait	Model	Prediction	Confidence in %	In training data
125439	oxygen_tolerance	BacteriaNetⓘ	microaerophile	98.40	no
125439	gram_stain	BacteriaNetⓘ	positive	89.70	no
125439	motility	BacteriaNetⓘ	no	76.40	no
125439	spore_formation	BacteriaNetⓘ	no	90.20	no

Predictions from bacterial phenotypic traits through improved machine learning using high-quality, curated datasets based on: Lacticaseibacillus casei DSM 20011 = JCM 1134 = ATCC 393 ATCC 393
NCBI: GCA_000829055.1

@ref	Trait	Model	Prediction	Confidence in %	In training data
125438	gram-positive	gram-positiveⓘ	yes	92.55	no
125438	anaerobic	anaerobicⓘ	no	85.64	yes
125438	aerobic	aerobicⓘ	no	91.27	no
125438	spore-forming	spore-formingⓘ	no	83.99	no
125438	thermophilic	thermophileⓘ	no	95.50	no
125438	flagellated	motile2+ⓘ	no	91.00	no

Literature

Topic	Title	Authors	Journal	DOI	Year
Metabolism	Some Lactobacillus L-lactate dehydrogenases exhibit comparable catalytic activities for pyruvate and oxaloacetate.	Arai K, Kamata T, Uchikoba H, Fushinobu S, Matsuzawa H, Taguchi H.	J Bacteriol	10.1128/jb.183.1.397-400.2001	2001
Metabolism	Assessment of Potential Probiotic and Synbiotic Properties of Lactic Acid Bacteria Grown In Vitro with Starch-Based Soluble Corn Fiber or Inulin.	Garcia-Nunez IM, Santacruz A, Serna-Saldivar SO, Hernandez SLC, Amaya Guerra CA.	Foods	10.3390/foods11244020	2022
	Irradiated Non-replicative Lactic Acid Bacteria Preserve Metabolic Activity While Exhibiting Diverse Immune Modulation.	Porfiri L, Burtscher J, Kangethe RT, Verhovsek D, Cattoli G, Domig KJ, Wijewardana V.	Front Vet Sci	10.3389/fvets.2022.859124	2022
Biotechnology	Investigating Safety and Technological Traits of a Leading Probiotic Species: Lacticaseibacillus paracasei.	Colautti A, Ginaldi F, Camprini L, Comi G, Reale A, Iacumin L.	Nutrients	10.3390/nu16142212	2024
	Occurrence and genetic diversity of prophage sequences identified in the genomes of L. casei group bacteria.	Jarocki P, Komon-Janczara E, Mlodzinska A, Sadurski J, Kolodzinska K, Laczmanski L, Panek J, Frac M.	Sci Rep	10.1038/s41598-023-35823-z	2023
Phylogeny	Molecular Routes to Specific Identification of the Lactobacillus Casei Group at the Species, Subspecies and Strain Level.	Jarocki P, Komon-Janczara E, Glibowska A, Dworniczak M, Pytka M, Korzeniowska-Kowal A, Wzorek A, Kordowska-Wiater M.	Int J Mol Sci	10.3390/ijms21082694	2020
	Valorization of Xylose-Rich Medium from Cynara cardunculus Stalks for Lactic Acid Production via Microbial Fermentation.	Russo G, Gelosia M, Fabbrizi G, Angrisano M, Policastro G, Cavalaglio G.	Polymers (Basel)	10.3390/polym16243577	2024
	Encapsulation of Lacticaseibacillus casei and Lactobacillus acidophilus using Elaeagnus angustifolia L. flour as encapsulating material by emulsion method.	Karkar B, Sahin S, Yilmaz-Ersan L, Akca B, Gunes ME, Ozakin C.	Food Sci Nutr	10.1002/fsn3.4328	2024
	Co-culture of Helicobacter pylori with oral microorganisms in human saliva.	Scholz KJ, Hohne A, Wittmer A, Hacker G, Hellwig E, Cieplik F, Waidner B, Al-Ahmad A.	Clin Oral Investig	10.1007/s00784-025-06160-4	2025
	Lactobacillus casei's Antitumor Potential in Colorectal Cancer: Exploring Mechanisms-A Systematic Review.	Abdorrashidi M, Heiat M, Yeganeh AV, Tohidinia A, Alizadeh A, Ramazani A, Gholizadeh H, Pouraskar T, Peypar MH.	Biomed Res Int	10.1155/bmri/4216722	2025
Genetics	Whole genome sequencing of Lacticaseibacillus casei KACC92338 strain with strong antioxidant activity, reveals genes and gene clusters of probiotic and antimicrobial potential.	Kandasamy S, Lee KH, Yoo J, Yun J, Kang HB, Kim JE, Oh MH, Ham JS.	Front Microbiol	10.3389/fmicb.2024.1458221	2024
	Safety and efficacy of a feed additive consisting of Lacticaseibacillus caseiIDAC 210415-01, Limosilactobacillus fermentumIDAC 210415-02, Levilactobacillus brevisIDAC 051120-02 and Enterococcus faeciumIDAC 181218-03 (K-9 Heritage Probiotic Blend®) for dogs (CanBiocin Inc.).	EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Bampidis V, Azimonti G, Bastos ML, Christensen H, Dusemund B, Durjava M, Kouba M, Lopez-Alonso M, Lopez Puente S, Marcon F, Mayo B, Pechova A, Petkova M, Ramos F, Sanz Y, Villa RE, Woutersen R, Anguita M, Brozzi R, Galobart J, Innocenti M, Ortuno J, Pettenati E, Garcia-Cazorla Y.	EFSA J	10.2903/j.efsa.2023.8105	2023
	Susceptibility of Lactobacillaceae Strains to Aminoglycoside Antibiotics in the Light of EFSA Guidelines.	Dec M, Herman-Ostrzyzek K, Zomer A, Urban-Chmiel R.	Life (Basel)	10.3390/life15050732	2025
	Enhancing Bread's Benefits: Investigating the Influence of Boosted Native Sourdough on FODMAP Modulation and Antioxidant Potential in Wheat Bread.	Pejcz E, Lachowicz-Wisniewska S, Nowicka P, Wojciechowicz-Budzisz A, Harasym J.	Foods	10.3390/foods12193552	2023
	Clinical Potential of Novel Microbial Therapeutic LP51 Based on Xerosis-Microbiome Index.	Kim S, Rahim MA, Tajdozian H, Barman I, Park HA, Yoon Y, Jo S, Lee S, Shuvo MSH, Bae SH, Lee H, Ju S, Park CE, Kim HK, Han JH, Kim JW, Yoon SG, Kim JH, Choi YG, Lee S, Seo H, Song HY.	Cells	10.3390/cells13232029	2024
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	Viability of Probiotic Microorganisms and the Effect of Their Addition to Fruit and Vegetable Juices.	Maia MS, Domingos MM, de Sao Jose JFB.	Microorganisms	10.3390/microorganisms11051335	2023
	A Novel qPCR Method for the Detection of Lactic Acid Bacteria in Fermented Milk.	Fan X, Li X, Zhang T, Xu J, Shi Z, Wu Z, Wu J, Pan D, Du L.	Foods	10.3390/foods10123066	2021
	Legumes and Legume-Based Beverages Fermented with Lactic Acid Bacteria as a Potential Carrier of Probiotics and Prebiotics.	Cichonska P, Ziarno M.	Microorganisms	10.3390/microorganisms10010091	2021
	2G-lactic acid from olive oil supply chain waste: olive leaves upcycling via Lactobacillus casei fermentation.	Gugel I, Marchetti F, Costa S, Gugel I, Baldini E, Vertuani S, Manfredini S.	Appl Microbiol Biotechnol	10.1007/s00253-024-13217-z	2024
	Application of ultrasound and microencapsulation on Limosilactobacillus reuteri DSM 17938 as a metabolic attenuation strategy for tomato juice probiotication.	Giordano I, Abuqwider J, Altamimi M, Di Monaco R, Puleo S, Mauriello G.	Heliyon	10.1016/j.heliyon.2022.e10969	2022
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Metabolism	Agrimonia procera exerts antimicrobial effects, modulates the expression of defensins and cytokines in colonocytes and increases the immune response in lipopolysaccharide-challenged piglets.	Graber T, Kluge H, Granica S, Horn G, Kalbitz J, Brandsch C, Breitenstein A, Brutting C, Stangl GI.	BMC Vet Res	10.1186/s12917-018-1680-0	2018
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	In vitro and in vivo studies of cellular lysis of oral bacteria by a lysozyme-protease-inorganic monovalent anion antibacterial system.	Pollock JJ, Shoda J, McNamara TF, Cho MI, Campbell A, Iacono VJ.	Infect Immun	10.1128/iai.45.3.610-617.1984	1984
	Exploring ultrasound-induced metabolic attenuation in Lacticaseibacillus casei ATCC 393-A combined approach using traditional methods and flow cytometry.	Giordano I, Salman M, Arioli S, Mora D, Mauriello G.	Front Microbiol	10.3389/fmicb.2025.1589054	2025
	Synbiotic Administration of d-Tagatose and Lacticaseibacillus casei ATCC 393 Improves Hyperlipidemia in BALB/c Mice by Modulating Gut Microbiota and Metabolic Parameters.	Cavdar M, Nogay NH, Dincer E, Karabulut D, Onal MG, Bolat S.	Food Sci Nutr	10.1002/fsn3.70597	2025
	Enhancing Probiotic Viability in Yogurt: The Role of Apple Fibers in Supporting Lacticaseibacillus casei ATCC 393 During Storage and Gastrointestinal Transit.	Dimitrellou D, Sakadani E, Kandylis P.	Foods	10.3390/foods14030376	2025
Genetics	Investigation of Anti-Cancerous Effects of L. casei -ATCC-393 and L. rhamnosus-GG on Apoptosis and Cell Cycle of B- CPAP Thyroid Cancer Cell line in Comparison to Fibroblast Cell Line.	Honardoost M, Soleimanifar F, Eslami S, Cheraghi S, Khamseh ME, Darvish M, Haddad Kashani H.	Avicenna J Med Biotechnol	10.18502/ajmb.v17i2.18561	2025
	Transcriptomic analysis reveals differential gene expression patterns of Lacticaseibacillus casei ATCC 393 in response to ultrasound stress.	Giordano I, Pasolli E, Mauriello G.	Ultrason Sonochem	10.1016/j.ultsonch.2024.106939	2024
	Lacticaseibacillus casei 393 modulates KRAS and APC expression and cytokine levels in colitis-associated colon cancer.	Santerre A, Huizar-Lopez MDR, Coronilla-Martinez J, Ortiz-Lazareno PC, Casas-Solis J.	J Gastrointest Oncol	10.21037/jgo-24-667	2025
	Probiotic Lactobacillus Species Modulate Immune Responses During Vaginal Epithelial Cell Colonization.	Valentine M, Rosati D, Dietschmann A, Schille TB, Netea MG, Hube B, Gresnigt MS.	J Infect Dis	10.1093/infdis/jiaf221	2025
Metabolism	Microencapsulation and sonication: A multiple physical approach to attenuate the probiotic Lacticaseibacillus casei ATCC 393.	Giordano I, Maresca D, Mauriello G.	Heliyon	10.1016/j.heliyon.2023.e23144	2023
	Inhibitory efficacy, production dynamics, and characterization of postbiotics of lactic acid bacteria.	Rahman MM, Sazili AQ, Ahmad SA, Khalil KA, Ismail-Fitry MR, Sarker MSK.	BMC Microbiol	10.1186/s12866-025-04123-z	2025
	Investigation of Probiotic Properties of Lacticaseibacillus casei 4 N-6 Strain Isolated From Cow Milk.	Dikbas N, Orman YC, Ucar S, Alim S.	Food Sci Nutr	10.1002/fsn3.70205	2025
Pathogenicity	The insertion of the inverted repeat of an insertion sequence (IS) element from Lacticaseibacillus rhamnosus changes the host range and stability of pGK12, a shuttle vector for lactic acid bacteria.	Xie Z, Jin Y-S, Klaenhammer TR, Miller MJ.	Appl Environ Microbiol	10.1128/aem.01908-24	2025
Metabolism	Ultrasound Attenuation Improves Some Surface Properties of the Probiotic Strain Lacticaseibacillus casei ATCC 393.	Giordano I, Mauriello G.	Microorganisms	10.3390/microorganisms11010142	2023
	Synergistic antibacterial effects of postbiotics combined with linezolid and amikacin against nosocomial pathogens.	Yaprak Colak E, Duran N.	Front Cell Infect Microbiol	10.3389/fcimb.2025.1616501	2025
	Multi-frequency sono-fermentation with mono and co-cultures of LAB synergistically enhance mulberry juice: Evidence from metabolic, micromorphological, sensorial, and computational approaches.	Yaqoob S, Imtiaz A, Khalifa I, Maqsood S, Ullah R, Shahat AA, Al-Asmari F, Murtaza MS, Qian JY, Ma Y.	Ultrason Sonochem	10.1016/j.ultsonch.2024.107117	2024
	Apple Waste/By-Products and Microbial Resources to Promote the Design of Added-Value Foods: A Review.	Selmi H, Presutto E, Totaro M, Spano G, Capozzi V, Fragasso M.	Foods	10.3390/foods14111850	2025
	Cas9-independent tracrRNA cytotoxicity in Lacticaseibacillus paracasei.	Arifah AQ, Vento JM, Kurrer I, Achmedov T, Beisel CL.	Microlife	10.1093/femsml/uqaf013	2025
	Lactiplantibacillus plantarum inhibited the growth of primary liver cancer by inducing early apoptosis and senescence, in vitro.	Duduyemi OP, Potapenko K, Limanska N, Kotsyuda S, Petriv N, Suo H, Gudzenko T, Ivanytsia V, Yevsa T.	Front Microbiol	10.3389/fmicb.2024.1451170	2024
	Lc-pPG-612-OmpU-CTB: A promising oral vaccine for protecting Carassius auratus against Vibrio mimicus infection.	Yang BT, Zhao T, Li HJ, Liang ZL, Cong W, Kang YH.	Fish Shellfish Immunol	10.1016/j.fsi.2023.108973	2023
	A novel synbiotic formulation prevents calcium oxalate stones by restoring gut microbiota homeostasis.	Li XM, Amier Y, Wan WL, Wang YQ, Lyu GR, Lu JL, Rao JY, Yang YY, Xun Y, Yu X.	BMC Microbiol	10.1186/s12866-025-04408-3	2025
	Optimizing Conditions in the Acid Tolerance Test for Potential Probiotics Using Response Surface Methodology.	Ko HI, Jeong CH, Hong SW, Eun JB, Kim TW.	Microbiol Spectr	10.1128/spectrum.01625-22	2022
Pathogenicity	The biological activity and potential of probiotics-derived extracellular vesicles as postbiotics in modulating microbiota-host communication.	Zhang X, Wang Y, E Q, Naveed M, Wang X, Liu Y, Li M.	J Nanobiotechnology	10.1186/s12951-025-03435-6	2025
	Physicochemical and functional characterisation of a food ingredient based on okara containing probiotics	Castellanos Fuentes AP, Bengoa A, Gagliarini N, Abraham A, de Escalada Pla MF, Flores SK.	Food and bioproducts processing : transactions of the Institution of Chemical Engineers, Part C.	10.1016/j.fbp.2022.07.001	2022
	Comparative Analysis of Lactobacillus Starter Cultures in Fermented Camel Milk: Effects on Viability, Antioxidant Properties, and Sensory Characteristics.	Shori AB.	Foods	10.3390/foods13223711	2024
	Fungal beta-Glucans Enhance Lactic Acid Bacteria Growth by Shortening Their Lag Phase and Increasing Growth Rate.	Buksa A, Petrovic F, Maglica Z.	Microorganisms	10.3390/microorganisms13061313	2025
	Study of the probiotic properties of Lacticaseibacillus casei subsp. casei NCIM 5752 and the optimization of whey-based media for the production of its biomass using response surface methodology.	Nanjaiah M, Rastogi NK, Devappa S.	3 Biotech	10.1007/s13205-023-03899-z	2024
	The Encapsulation Strategies for Targeted Delivery of Probiotics in Preventing and Treating Colorectal Cancer: A Review.	Zhong H, Jiang J, Hussain M, Zhang H, Chen L, Guan R.	Adv Sci (Weinh)	10.1002/advs.202500304	2025
	Swine Gut Lactic Acid Bacteria and Their Exopolysaccharides Differentially Modulate Toll-like Receptor Signaling Depending on the Agave Fructans Used as a Carbon Source.	Sanhueza-Carrera EA, Fernandez-Lainez C, Castro-De la Mora C, Ortega-Alvarez D, Mendoza-Camacho C, Cortez-Sanchez JM, Perez-Guille B, de Vos P, Lopez-Velazquez G.	Animals (Basel)	10.3390/ani15071047	2025
	Synergistic enhancement in the mulberry juice's antioxidant activity by using lactic acid bacteria co-culture fermentation.	Yaqoob S, Gouda MM, Mubeen B, Imtiaz A, Murtaza MS, Awan KA, Rehman A, Alsulami T, Khalifa I, Ma Y.	Sci Rep	10.1038/s41598-024-81023-8	2025
	Selenite Bioremediation by Food-Grade Probiotic Lactobacillus casei ATCC 393: Insights from Proteomics Analysis.	Qiao L, Dou X, Song X, Chang J, Zeng X, Zhu L, Xu C.	Microbiol Spectr	10.1128/spectrum.00659-23	2023
	Antimicrobial activity of cell-free supernatant of lactic acid bacteria on spoilage bacteria of vacuum-packed sliced emulsion-type sausages.	Tajbakhsh S, Eskandari MH, Shekarforoush SS.	Iran J Vet Res	10.22099/ijvr.2024.49361.7255	2024
	Ultrasound can increase biofilm formation by Lactiplantibacillus plantarum and Bifidobacterium spp.	Racioppo A, Speranza B, Altieri C, Sinigaglia M, Corbo MR, Bevilacqua A.	Front Microbiol	10.3389/fmicb.2023.1094671	2023
	Hybrid Systems of Oleogels and Probiotic-Loaded Alginate Carriers for Potential Application in Cosmetics.	Letocha A, Miastkowska M, Sikora E, Michalczyk A, Liszka-Skoczylas M, Witczak M.	Molecules	10.3390/molecules29245984	2024
	Context-dependent differences in the functional responses of Lactobacillaceae strains to fermentable sugars.	Suissa R, Oved R, Maan H, Hadad U, Gilhar O, Meijler MM, Koren O, Kolodkin-Gal I.	Front Microbiol	10.3389/fmicb.2022.949932	2022
Pathogenicity	Gut instinct: harnessing the power of probiotics to tame pathogenic signaling pathways in ulcerative colitis.	Hsu CY, Hsu CY, Mustafa MA, Moath Omar T, Taher SG, Ubaid M, Gilmanova NS, Nasrat Abdulraheem M, Saadh MJ, Athab AH, Mirzaei R, Karampoor S.	Front Med (Lausanne)	10.3389/fmed.2024.1396789	2024
Enzymology	Application of 16S rRNA virtual RFLP for the discrimination of some closely taxonomic-related lactobacilli species.	Laref N, Belkheir K.	J Genet Eng Biotechnol	10.1186/s43141-022-00448-8	2022
	Agarooligosaccharides as a novel concept in prebiotics: selective inhibition of Ruminococcus gnavus and Fusobacterium nucleatum while preserving Bifidobacteria, Lactobacillales in vitro, and inhibiting Lachnospiraceae in vivo.	Fujii T, Karasawa K, Takahashi H, Shirai I, Funasaka K, Ohno E, Hirooka Y, Tochio T.	Microbiology (Reading)	10.1099/mic.0.001510	2024
	Application of Probiotics in Foods: A Comprehensive Review of Benefits, Challenges, and Future Perspectives.	Grujovic MZ, Semedo-Lemsaddek T, Markovic KG.	Foods	10.3390/foods14173088	2025
	In Vitro Selection of Lactobacillus and Bifidobacterium Probiotic Strains for the Management of Oral Pathobiont Infections Associated to Systemic Diseases.	Zanetta P, Squarzanti DF, di Coste A, Rolla R, Valletti PA, Garzaro M, Dell'Era V, Amoruso A, Pane M, Azzimonti B.	Int J Mol Sci	10.3390/ijms232416163	2022
	Anti-Obesity Potential through Regulation of Carbohydrate Uptake and Gene Expression in Intestinal Epithelial Cells by the Probiotic Lactiplantibacillus plantarum MGEL20154 from Fermented Food.	Park SY, Choi JW, Oh DN, Lee EJ, Kim DP, Yoon SJ, Jang WJ, Han SJ, Lee S, Lee JM.	J Microbiol Biotechnol	10.4014/jmb.2212.12005	2023
	Promising application of probiotic microorganisms as Pickering emulsions stabilizers.	Nejadmansouri M, Eskandari MH, Yousefi GH, Riazi M, Hosseini SMH.	Sci Rep	10.1038/s41598-023-43087-w	2023
	Emerging Nonthermal Technologies for the Production of Postbiotics.	Thirumdas R, Mudgil P.	Compr Rev Food Sci Food Saf	10.1111/1541-4337.70335	2025
Genetics	Complete Genome Sequencing and Comparative Genomics of Three Potential Probiotic Strains, Lacticaseibacillus casei FBL6, Lacticaseibacillus chiayiensis FBL7, and Lacticaseibacillus zeae FBL8.	Kim E, Yang SM, Kim D, Kim HY.	Front Microbiol	10.3389/fmicb.2021.794315	2021
	Mucin Binding Protein of Lactobacillus casei Inhibits HT-29 Colorectal Cancer Cell Proliferation.	Ju X, Wu X, Chen Y, Cui S, Cai Z, Zhao L, Hao Y, Zhou F, Chen F, Yu Z, Yang D.	Nutrients	10.3390/nu15102314	2023
	Bioaccessibility and Microencapsulation of Lactobacillus sp. to Enhance Nham Protein Hydrolysates in Thai Fermented Sausage.	Phupaboon S, Kontongdee P, Hashim FJ, Kanpipit N, Matra M, Totakul P, Prommachart R, Phesatcha B, Wanapat M.	Foods	10.3390/foods11233846	2022
	Nutrition and Health through the Use of Probiotic Strains in Fermentation to Produce Non-Dairy Functional Beverage Products Supporting Gut Microbiota.	Dahiya D, Nigam PS.	Foods	10.3390/foods11182760	2022
	Probiotic Viability and Bioactive Properties of Buffalo Yoghurt Produced Using High Cholesterol-Assimilating Probiotic Strains.	Akbal S, Ugur Gecer E, Erturkmen P.	Vet Med Sci	10.1002/vms3.70233	2025
	New Wild-Type Lacticaseibacillus rhamnosus Strains as Candidates to Manage Type 1 Diabetes.	Nelios G, Santarmaki V, Pavlatou C, Dimitrellou D, Kourkoutas Y.	Microorganisms	10.3390/microorganisms10020272	2022
	Effect of Encapsulation of Lactobacillus casei in Alginate-Tapioca Flour Microspheres Coated with Different Biopolymers on the Viability of Probiotic Bacteria.	Letocha A, Michalczyk A, Miastkowska M, Sikora E.	ACS Appl Mater Interfaces	10.1021/acsami.4c10187	2024
	Evaluation of Dietary Supplements Containing Viable Bacteria by Cultivation/MALDI-TOF Mass Spectrometry and PCR Identification.	Mohar Lorbeg P, Golob M, Kramer M, Treven P, Bogovic Matijasic B.	Front Microbiol	10.3389/fmicb.2021.700138	2021
	Development of engineered probiotics with tailored functional properties and their application in food science.	Pramanik S, Venkatraman S, Vaidyanathan VK.	Food Sci Biotechnol	10.1007/s10068-023-01252-x	2023
Enzymology	High performance anion exchange chromatography purification of probiotic bacterial extracellular vesicles enhances purity and anti-inflammatory efficacy.	Pirolli NH, Reus LSC, Mamczarz Z, Khan S, Bentley WE, Jay SM.	Biotechnol Bioeng	10.1002/bit.28522	2023
	Probiotic Properties of Lactic Acid Bacteria Newly Isolated from Algerian Raw Cow's Milk.	Kouadri Boudjelthia N, Belabbas M, Bekenniche N, Monnoye M, Gerard P, Riazi A.	Microorganisms	10.3390/microorganisms11082091	2023
Pathogenicity	Novel Horizons in Postbiotics: Lactobacillaceae Extracellular Vesicles and Their Applications in Health and Disease.	Gonzalez-Lozano E, Garcia-Garcia J, Galvez J, Hidalgo-Garcia L, Rodriguez-Nogales A, Rodriguez-Cabezas ME, Sanchez M.	Nutrients	10.3390/nu14245296	2022
	Extracellular Vesicles of Probiotics: Shedding Light on the Biological Activity and Future Applications.	Krzyzek P, Marinacci B, Vitale I, Grande R.	Pharmaceutics	10.3390/pharmaceutics15020522	2023
	Postbiotic mediators derived from Lactobacillus species enhance riboflavin-mediated antimicrobial photodynamic therapy for eradication of Streptococcus mutans planktonic and biofilm growth.	Pourhajibagher M, Ghafari HA, Bahador A.	BMC Oral Health	10.1186/s12903-024-04620-z	2024
Enzymology	Characterisation of recombinant GH 3 beta-glucosidase from beta-glucan producing Levilactobacillus brevis TMW 1.2112.	Bockwoldt JA, Ehrmann MA.	Antonie Van Leeuwenhoek	10.1007/s10482-022-01751-7	2022
	Lactobacillus casei and Epidermal Growth Factor Prevent Osmotic Stress-Induced Tight Junction Disruption in Caco-2 Cell Monolayers.	Samak G, Rao R, Rao R.	Cells	10.3390/cells10123578	2021
	Exploring the antimicrobial potential of lactobacilli against early-stage and mature biofilms of Staphylococcus aureus and Pseudomonas aeruginosa.	Singh N, Gulhane RD, Singh A, Goel M, Udelal PP, Sangwan V, Sihag MK, Goel G, Panwar H, Puniya AK.	Front Chem	10.3389/fchem.2025.1425666	2025
	Probiotics: an alternative anti-parasite therapy.	Mandal S, Mondal C, Lyndem LM.	J Parasit Dis	10.1007/s12639-024-01680-4	2024
	Metabolic insights of lactic acid bacteria in reducing off-flavors and antinutrients in plant-based fermented dairy alternatives.	Molina GES, Ras G, da Silva DF, Duedahl-Olesen L, Hansen EB, Bang-Berthelsen CH.	Compr Rev Food Sci Food Saf	10.1111/1541-4337.70134	2025
	How probiotics, prebiotics, synbiotics, and postbiotics prevent dental caries: an oral microbiota perspective.	Luo SC, Wei SM, Luo XT, Yang QQ, Wong KH, Cheung PCK, Zhang BB.	NPJ Biofilms Microbiomes	10.1038/s41522-024-00488-7	2024
	Potential Health Benefits of Fermented Vegetables with Additions of Lacticaseibacillus rhamnosus GG and Polyphenol Vitexin Based on Their Antioxidant Properties and Prohealth Profiles.	Ngamsamer C, Muangnoi C, Tongkhao K, Sae-Tan S, Treesuwan K, Sirivarasai J.	Foods	10.3390/foods13070982	2024
	Structural characterization and partial properties of dextran produced by Leuconostoc mesenteroides RSG7 from pepino.	Wang B, Sun X, Xu M, Wang F, Liu W, Wu B.	Front Microbiol	10.3389/fmicb.2023.1108120	2023
Enzymology	Isolation and characterization of Lactobacillus-derived membrane vesicles.	Dean SN, Leary DH, Sullivan CJ, Oh E, Walper SA.	Sci Rep	10.1038/s41598-018-37120-6	2019
	Recent advances in genetic tools for engineering probiotic lactic acid bacteria.	Mugwanda K, Hamese S, Van Zyl WF, Prinsloo E, Du Plessis M, Dicks LMT, Thimiri Govinda Raj DB.	Biosci Rep	10.1042/bsr20211299	2023
	Characterization of extracellular vesicles from Lactiplantibacillus plantarum.	Kurata A, Kiyohara S, Imai T, Yamasaki-Yashiki S, Zaima N, Moriyama T, Kishimoto N, Uegaki K.	Sci Rep	10.1038/s41598-022-17629-7	2022
	Probiotics, Their Extracellular Vesicles and Infectious Diseases.	Dominguez Rubio AP, D'Antoni CL, Piuri M, Perez OE.	Front Microbiol	10.3389/fmicb.2022.864720	2022
Enzymology	A new method for quantitative detection of Lactobacillus casei based on casx gene and its application.	Pang X, Jia Z, Lu J, Zhang S, Zhang C, Zhang M, Lv J.	BMC Biotechnol	10.1186/s12896-019-0587-6	2019
	The potential role of adherence factors in probiotic function in the gastrointestinal tract of adults and pediatrics: a narrative review of experimental and human studies.	Gorreja F, Walker WA.	Gut Microbes	10.1080/19490976.2022.2149214	2022
	Screening and Characterization of Some Lactobacillaceae for Detection of Cholesterol-Lowering Activities.	Frappier M, Auclair J, Bouasker S, Gunaratnam S, Diarra C, Millette M.	Probiotics Antimicrob Proteins	10.1007/s12602-022-09959-9	2022
	Lacticaseibacillus spp.; Probiotic candidates from Palmyra palm sugar possesses antimicrobial and anti-biofilm activities against methicillin-resistant Staphylococcus aureus.	Mitsuwan W, Sornsenee P, Romyasamit C.	Vet World	10.14202/vetworld.2022.299-308	2022
	AhR ligands from LGG metabolites promote piglet intestinal ILC3 activation and IL-22 secretion to inhibit PEDV infection.	Wang J, Zhao Y, Cui T, Bao H, Gao M, Cheng M, Sun Y, Lu Y, Guan J, Zhang D, Jiang Y, Huang H, Shi C, Wang J, Wang N, Hu J, Yang W, Qian H, Jiang Q, Yang G, Zeng Y, Wang C, Cao X.	J Virol	10.1128/jvi.01039-24	2024
	The construction of recombinant Lactobacillus casei vaccine of PEDV and its immune responses in mice.	Li X, Zhang B, Zhang D, Liu S, Ren J.	BMC Vet Res	10.1186/s12917-021-02885-y	2021
Pathogenicity	Lactobacilli and Bifidobacterium as anti-atherosclerotic agents.	Abdi M, Esmaeili Gouvarchin Ghaleh H, Ranjbar R.	Iran J Basic Med Sci	10.22038/ijbms.2022.63860.14073	2022
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	Complete genome sequence of the probiotic Lactobacillus casei strain BL23.	Maze A, Boel G, Zuniga M, Bourand A, Loux V, Yebra MJ, Monedero V, Correia K, Jacques N, Beaufils S, Poncet S, Joyet P, Milohanic E, Casaregola S, Auffray Y, Perez-Martinez G, Gibrat JF, Zagorec M, Francke C, Hartke A, Deutscher J.	J Bacteriol	10.1128/jb.00076-10	2010
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Pathogenicity	Characterization of a Sea Buckthorn Extract and Its Effect on Free and Encapsulated Lactobacillus casei.	Pop OL, Dulf FV, Cuibus L, Castro-Giraldez M, Fito PJ, Vodnar DC, Coman C, Socaciu C, Suharoschi R.	Int J Mol Sci	10.3390/ijms18122513	2017
Genetics	Genome Sequencing of five Lacticaseibacillus Strains and Analysis of Type I and II Toxin-Antitoxin System Distribution.	Levante A, Lazzi C, Vatsellas G, Chatzopoulos D, Dionellis VS, Makrythanasis P, Neviani E, Folli C.	Microorganisms	10.3390/microorganisms9030648	2021
	A probiotic bi-functional peptidoglycan hydrolase sheds NOD2 ligands to regulate gut homeostasis in female mice.	Gao J, Wang L, Jiang J, Xu Q, Zeng N, Lu B, Yuan P, Sun K, Zhou H, He X.	Nat Commun	10.1038/s41467-023-38950-3	2023
	Physiological Characteristics of Lactobacillus casei Strains and Their Alleviation Effects against Inflammatory Bowel Disease.	Liu Y, Li Y, Yu X, Yu L, Tian F, Zhao J, Zhang H, Zhai Q, Chen W.	J Microbiol Biotechnol	10.4014/jmb.2003.03041	2021
Biotechnology	Construction of a food-grade cell surface display system for Lactobacillus casei.	Qin J, Wang X, Kong J, Ma C, Xu P.	Microbiol Res	10.1016/j.micres.2014.02.001	2014
Metabolism	Cheese whey to biohydrogen and useful organic acids: A non-pathogenic microbial treatment by L. acidophilus.	Pandey A, Srivastava S, Rai P, Duke M.	Sci Rep	10.1038/s41598-019-42752-3	2019
Pathogenicity	Lactobacillus casei Ghosts as a Vehicle for the Delivery of DNA Vaccines Mediate Immune Responses.	Yu X, Wang L, Yang X, Zhang S, Li G, Zhang L, Li J, Wang X, Zhou H, Jiang Y, Cui W, Li Y, Tang L, Qiao X.	Front Immunol	10.3389/fimmu.2022.849409	2022
Metabolism	Physicochemical and biological properties of novel chlorhexidine-loaded nanotube-modified dentin adhesive.	Feitosa SA, Palasuk J, Geraldeli S, Windsor LJ, Bottino MC.	J Biomed Mater Res B Appl Biomater	10.1002/jbm.b.34183	2019
Metabolism	Coupling the recombineering to Cre-lox system enables simplified large-scale genome deletion in Lactobacillus casei.	Xin Y, Guo T, Mu Y, Kong J.	Microb Cell Fact	10.1186/s12934-018-0872-4	2018
	Side Streams of Vegetable Processing and Its Bioactive Compounds Support Microbiota, Intestine Milieu, and Immune System.	Fotschki J, Ogrodowczyk AM, Wroblewska B, Juskiewicz J.	Molecules	10.3390/molecules28114340	2023
	Immunogenicity of recombinant classic swine fever virus CD8(+) T lymphocyte epitope and porcine parvovirus VP2 antigen coexpressed by Lactobacillus casei in swine via oral vaccination.	Xu Y, Cui L, Tian C, Zhang G, Huo G, Tang L, Li Y.	Clin Vaccine Immunol	10.1128/cvi.05204-11	2011
	In situ delivery of passive immunity by lactobacilli producing single-chain antibodies.	Kruger C, Hu Y, Pan Q, Marcotte H, Hultberg A, Delwar D, van Dalen PJ, Pouwels PH, Leer RJ, Kelly CG, van Dollenweerd C, Ma JK, Hammarstrom L.	Nat Biotechnol	10.1038/nbt0702-702	2002
	Propolis varnish: antimicrobial properties against cariogenic bacteria, cytotoxicity, and sustained-release profile.	De Luca MP, Franca JR, Macedo FA, Grenho L, Cortes ME, Faraco AA, Moreira AN, Santos VR.	Biomed Res Int	10.1155/2014/348647	2014
	Oral immunization of mice with a probiotic Lactobacillus casei constitutively expressing the alpha-toxoid induces protective immunity against Clostridium perfringens alpha-toxin.	Gao X, Ma Y, Wang Z, Bai J, Jia S, Feng B, Jiang Y, Cui W, Tang L, Li Y, Wang L, Xu Y.	Virulence	10.1080/21505594.2019.1582975	2019
	Biotechnological Applications of Probiotics: A Multifarious Weapon to Disease and Metabolic Abnormality.	Singh RP, Shadan A, Ma Y.	Probiotics Antimicrob Proteins	10.1007/s12602-022-09992-8	2022
Genetics	Development of a counterselectable seamless mutagenesis system in lactic acid bacteria.	Xin Y, Guo T, Mu Y, Kong J.	Microb Cell Fact	10.1186/s12934-017-0731-8	2017
	Comparison of the immune responses induced by oral immunization of mice with Lactobacillus casei-expressing porcine parvovirus VP2 and VP2 fused to Escherichia coli heat-labile enterotoxin B subunit protein.	Liu D, Wang X, Ge J, Liu S, Li Y.	Comp Immunol Microbiol Infect Dis	10.1016/j.cimid.2010.02.004	2011
Pathogenicity	Enhanced antifungal activity of bovine lactoferrin-producing probiotic Lactobacillus casei in the murine model of vulvovaginal candidiasis.	Liao H, Liu S, Wang H, Su H, Liu Z.	BMC Microbiol	10.1186/s12866-018-1370-x	2019
	Immunogenicity of eGFP-Marked Recombinant Lactobacillus casei against Transmissible Gastroenteritis Virus and Porcine Epidemic Diarrhea Virus.	Yu M, Wang L, Ma S, Wang X, Wang Y, Xiao Y, Jiang Y, Qiao X, Tang L, Xu Y, Li Y.	Viruses	10.3390/v9100274	2017
	Mapping the Key Technological and Functional Characteristics of Indigenous Lactic Acid Bacteria Isolated from Greek Traditional Dairy Products.	Kamarinou CS, Papadopoulou OS, Doulgeraki AI, Tassou CC, Galanis A, Chorianopoulos NG, Argyri AA.	Microorganisms	10.3390/microorganisms10020246	2022
	Recombinant porcine rotavirus VP4 and VP4-LTB expressed in Lactobacillus casei induced mucosal and systemic antibody responses in mice.	Qiao X, Li G, Wang X, Li X, Liu M, Li Y.	BMC Microbiol	10.1186/1471-2180-9-249	2009
	New method for evaluation of genotoxicity, based on the use of real-time PCR and lysogenic gram-positive and gram-negative bacteria.	Soberon N, Martin R, Suarez JE.	Appl Environ Microbiol	10.1128/aem.00407-07	2007
	Effect of a novel quaternary ammonium methacrylate polymer (QAMP) on adhesion and antibacterial properties of dental adhesives.	Pupo YM, Farago PV, Nadal JM, Simao LC, Esmerino LA, Gomes OM, Gomes JC.	Int J Mol Sci	10.3390/ijms15058998	2014
	Reduction of tumor necrosis factor alpha-inducing capacity of recombinant Lactobacillus casei via expression of Salmonella OmpC.	Kajikawa A, Igimi S.	Appl Environ Microbiol	10.1128/aem.01916-08	2009
Metabolism	Recombinant fusion protein of cholera toxin B subunit with YVAD secreted by Lactobacillus casei inhibits lipopolysaccharide-induced caspase-1 activation and subsequent IL-1 beta secretion in Caco-2 cells.	Hiramatsu Y, Yamamoto M, Satho T, Irie K, Kai A, Uyeda S, Fukumitsu Y, Toda A, Miyata T, Miake F, Arakawa T, Kashige N.	BMC Biotechnol	10.1186/1472-6750-14-38	2014
	Comparative genomic and functional analysis of Lactobacillus casei and Lactobacillus rhamnosus strains marketed as probiotics.	Douillard FP, Ribbera A, Jarvinen HM, Kant R, Pietila TE, Randazzo C, Paulin L, Laine PK, Caggia C, von Ossowski I, Reunanen J, Satokari R, Salminen S, Palva A, de Vos WM.	Appl Environ Microbiol	10.1128/aem.03467-12	2013
	Evidence that Lactobacillus casei insertion element ISL1 has a narrow host range.	Shimizu-Kadota M, Flickinger JL, Chassy BM.	J Bacteriol	10.1128/jb.170.10.4976-4978.1988	1988
	Exposing the secrets of two well-known Lactobacillus casei phages, J-1 and PL-1, by genomic and structural analysis.	Dieterle ME, Bowman C, Batthyany C, Lanzarotti E, Turjanski A, Hatfull G, Piuri M.	Appl Environ Microbiol	10.1128/aem.02771-14	2014
Metabolism	Constitutive delivery of bovine beta-lactoglobulin to the digestive tracts of gnotobiotic mice by engineered Lactobacillus casei.	Hazebrouck S, Oozeer R, Adel-Patient K, Langella P, Rabot S, Wal JM, Corthier G.	Appl Environ Microbiol	10.1128/aem.01032-06	2006
	Intragastric immunization with recombinant Lactobacillus casei expressing flagellar antigen confers antibody-independent protective immunity against Salmonella enterica serovar Enteritidis.	Kajikawa A, Satoh E, Leer RJ, Yamamoto S, Igimi S.	Vaccine	10.1016/j.vaccine.2007.01.055	2007
	Cell surface characteristics of Lactobacillus casei subsp. casei, Lactobacillus paracasei subsp. paracasei, and Lactobacillus rhamnosus strains.	Pelletier C, Bouley C, Cayuela C, Bouttier S, Bourlioux P, Bellon-Fontaine MN.	Appl Environ Microbiol	10.1128/aem.63.5.1725-1731.1997	1997
	The Lactobacillus acidophilus S-layer protein gene expression site comprises two consensus promoter sequences, one of which directs transcription of stable mRNA.	Boot HJ, Kolen CP, Andreadaki FJ, Leer RJ, Pouwels PH.	J Bacteriol	10.1128/jb.178.18.5388-5394.1996	1996
Metabolism	Proteomic analysis of Lactobacillus casei GCRL163 cell-free extracts reveals a SecB homolog and other biomarkers of prolonged heat stress.	Adu KT, Wilson R, Nichols DS, Baker AL, Bowman JP, Britz ML.	PLoS One	10.1371/journal.pone.0206317	2018
	Inhibition of Staphylococcus aureus invasion into bovine mammary epithelial cells by contact with live Lactobacillus casei.	Bouchard DS, Rault L, Berkova N, Le Loir Y, Even S.	Appl Environ Microbiol	10.1128/aem.03323-12	2013
Metabolism	Ca2+-citrate uptake and metabolism in Lactobacillus casei ATCC 334.	Mortera P, Pudlik A, Magni C, Alarcon S, Lolkema JS.	Appl Environ Microbiol	10.1128/aem.00925-13	2013
Pathogenicity	Modification of peptidoglycan precursors is a common feature of the low-level vancomycin-resistant VANB-type Enterococcus D366 and of the naturally glycopeptide-resistant species Lactobacillus casei, Pediococcus pentosaceus, Leuconostoc mesenteroides, and Enterococcus gallinarum.	Billot-Klein D, Gutmann L, Sable S, Guittet E, van Heijenoort J.	J Bacteriol	10.1128/jb.176.8.2398-2405.1994	1994
Metabolism	Lactobacillus casei is able to survive and initiate protein synthesis during its transit in the digestive tract of human flora-associated mice.	Oozeer R, Goupil-Feuillerat N, Alpert CA, van de Guchte M, Anba J, Mengaud J, Corthier G.	Appl Environ Microbiol	10.1128/aem.68.7.3570-3574.2002	2002
	The lac operon of Lactobacillus casei contains lacT, a gene coding for a protein of the Bg1G family of transcriptional antiterminators.	Alpert CA, Siebers U.	J Bacteriol	10.1128/jb.179.5.1555-1562.1997	1997
Genetics	The dilemma of phage taxonomy illustrated by comparative genomics of Sfi21-like Siphoviridae in lactic acid bacteria.	Proux C, van Sinderen D, Suarez J, Garcia P, Ladero V, Fitzgerald GF, Desiere F, Brussow H.	J Bacteriol	10.1128/jb.184.21.6026-6036.2002	2002
Metabolism	Identification of a gene cluster enabling Lactobacillus casei BL23 to utilize myo-inositol.	Yebra MJ, Zuniga M, Beaufils S, Perez-Martinez G, Deutscher J, Monedero V.	Appl Environ Microbiol	10.1128/aem.00243-07	2007
Metabolism	Production of human papillomavirus type 16 L1 virus-like particles by recombinant Lactobacillus casei cells.	Aires KA, Cianciarullo AM, Carneiro SM, Villa LL, Boccardo E, Perez-Martinez G, Perez-Arellano I, Oliveira ML, Ho PL.	Appl Environ Microbiol	10.1128/aem.72.1.745-752.2006	2006
Enzymology	Characterization and molecular cloning of cryptic plasmids isolated from Lactobacillus casei.	Lee-Wickner LJ, Chassy BM.	Appl Environ Microbiol	10.1128/aem.49.5.1154-1161.1985	1985
Enzymology	Consensus-degenerate hybrid oligonucleotide primers for amplification of priming glycosyltransferase genes of the exopolysaccharide locus in strains of the Lactobacillus casei group.	Provencher C, LaPointe G, Sirois S, Van Calsteren MR, Roy D.	Appl Environ Microbiol	10.1128/aem.69.6.3299-3307.2003	2003
Enzymology	Distribution of proteins similar to IIIManH and IIIManL of the Streptococcus salivarius phosphoenolpyruvate:mannose-glucose phosphotransferase system among oral and nonoral bacteria.	Pelletier M, Frenette M, Vadeboncoeur C.	J Bacteriol	10.1128/jb.177.9.2270-2275.1995	1995
	Enhancement of host resistance against Listeria infection by Lactobacillus casei: role of macrophages.	Sato K.	Infect Immun	10.1128/iai.44.2.445-451.1984	1984
Metabolism	Regulation of lactose-phosphoenolpyruvate-dependent phosphotransferase system and beta-D-phosphogalactoside galactohydrolase activities in Lactobacillus casei.	Chassy BM, Thompson J.	J Bacteriol	10.1128/jb.154.3.1195-1203.1983	1983
	Immunological cross-reactivity of oral non-streptococcal bacteria with mammalian tissue.	Stinson MW, Nisengard RJ, Pelonero L, Drinnan AJ.	Infect Immun	10.1128/iai.24.2.532-538.1979	1979
Metabolism	Phosphorylation of HPr by the bifunctional HPr Kinase/P-ser-HPr phosphatase from Lactobacillus casei controls catabolite repression and inducer exclusion but not inducer expulsion.	Dossonnet V, Monedero V, Zagorec M, Galinier A, Perez-Martinez G, Deutscher J.	J Bacteriol	10.1128/jb.182.9.2582-2590.2000	2000
Enzymology	Purification and characterization of the IIIXtl phospho-carrier protein of the phosphoenolpyruvate-dependent xylitol:phosphotransferase found in Lactobacillus casei C183.	London J, Hausman SZ.	J Bacteriol	10.1128/jb.156.2.611-619.1983	1983
Metabolism	Regulation and characterization of the galactose-phosphoenolpyruvate-dependent phosphotransferase system in Lactobacillus casei.	Chassy BM, Thompson J.	J Bacteriol	10.1128/jb.154.3.1204-1214.1983	1983
	Fermentation of Rubus dolichocarpus juice using Lactobacillus gasseri and Lacticaseibacillus casei and protecting phenolic compounds by Stevia extract during cold storage.	Karimkhani MM, Jamshidi A, Nasrollahzadeh M, Armin M, Jafari SM, Zeinali T.	Sci Rep	10.1038/s41598-024-56235-7	2024
	The Prospective Beneficial Effects of Red Laser Exposure on Lactocaseibacillus casei Fermentation of Skim Milk.	Mohamed MSM, Elshaghabee FMF, Alharbi SA, El-Hussein A.	Biology (Basel)	10.3390/biology9090256	2020
	Synbiotic yogurt with nanoparticle entrapped rice straw hemicellulose for immediate probiotic support and prebiotic delivery.	Ismail SA, Fayed B, El-Sayed HS, Taie HAA, Hassan AA.	NPJ Sci Food	10.1038/s41538-025-00539-z	2025
Metabolism	Effects of Agitation Speed and Kinetic Studies on Probiotication of Pomegranate Juice with Lactobacillus casei.	Mustafa SM, Chua LS, El-Enshasy HA.	Molecules	10.3390/molecules24132357	2019
	alpha-Lipoic acid increases phagocytosis of some lactic acid bacteria via modulation of CD36 expression.	Nomura N, Miyadai N, Kawase I.	Biosci Microbiota Food Health	10.12938/bmfh.2024-019	2025
	Adjacent-possible ecological niche: growth of Lactobacillus species co-cultured with Escherichia coli in a synthetic minimal medium.	Mizuno K, Mizuno M, Yamauchi M, Takemura AJ, Medrano Romero V, Morikawa K.	Sci Rep	10.1038/s41598-017-12894-3	2017
Pathogenicity	Anti-Inflammation and Anti-Melanogenic Effects of Maca Root Extracts Fermented Using Lactobacillus Strains.	Yang J, Cho H, Gil M, Kim KE.	Antioxidants (Basel)	10.3390/antiox12040798	2023
	Inhibitory Effects of Fermented Sprouted Oat Extracts on Oxidative Stress and Melanin Overproduction.	Cho H, Yang J, Kang JY, Kim KE.	Antioxidants (Basel)	10.3390/antiox13050544	2024
	Advancements in the Pharmaceutical Applications of Probiotics: Dosage Forms and Formulation Technology.	Baral KC, Bajracharya R, Lee SH, Han HK.	Int J Nanomedicine	10.2147/ijn.s337427	2021
	Materials Used for the Microencapsulation of Probiotic Bacteria in the Food Industry.	Kowalska E, Ziarno M, Ekielski A, Zelazinski T.	Molecules	10.3390/molecules27103321	2022
	Effect of a Diet Supplemented with Sphingomyelin and Probiotics on Colon Cancer Development in Mice.	Marzo F, Jauregui P, Barrenetxe J, Martinez-Penuela A, Ibanez FC, Milagro FI.	Probiotics Antimicrob Proteins	10.1007/s12602-022-09916-6	2022
	Function and Structure of Lacticaseibacillus casei GH35 beta-Galactosidase LBCZ_0230 with High Hydrolytic Activity to Lacto-N-biose I and Galacto-N-biose.	Saburi W, Ota T, Kato K, Tagami T, Yamashita K, Yao M, Mori H.	J Appl Glycosci (1999)	10.5458/jag.jag.jag-2022_0014	2023
	Carotenoid productivity in human intestinal bacteria Eubacterium limosum and Leuconostoc mesenteroides with functional analysis of their carotenoid biosynthesis genes.	Matsumoto W, Takemura M, Nanaura H, Ami Y, Maoka T, Shindo K, Kurihara S, Misawa N.	Eng Microbiol	10.1016/j.engmic.2024.100147	2024
	Evaluation of the Immunogenicity in Mice Orally Immunized with Recombinant Lactobacillus casei Expressing Porcine Epidemic Diarrhea Virus S1 Protein.	Xiao Y, Wang X, Li Y, Li F, Zhao H, Shao Y, Zhang L, Ding G, Li J, Jiang Y, Cui W, Shan Z, Zhou H, Wang L, Qiao X, Tang L, Li Y	Viruses	10.3390/v14050890	2022
	Antiparasitic Action of Lactobacillus casei ATCC 393 and Lactobacillus paracasei CNCM Strains in CD-1 Mice Experimentally Infected with Trichinella britovi.	Boros Z, Baies MH, Vodnar DC, Gherman CM, Borsan SD, Cozma-Petrut A, Lefkaditis M, Gyorke A, Cozma V	Pathogens	10.3390/pathogens11030296	2022
	Lacticaseibacillus casei ATCC 393 Cannot Colonize the Gastrointestinal Tract of Crucian Carp.	Zhang H, Mu X, Wang H, Wang H, Wang H, Li Y, Mu Y, Song J, Xia L	Microorganisms	10.3390/microorganisms9122547	2021
Metabolism	The Role of Vasoactive Intestinal Peptide and Mast Cells in the Regulatory Effect of Lactobacillus casei ATCC 393 on Intestinal Mucosal Immune Barrier.	Song X, Pi S, Gao Y, Zhou F, Yan S, Chen Y, Qiao L, Dou X, Shao D, Xu C	Front Immunol	10.3389/fimmu.2021.723173	2021
	Polymer and Crosslinker Content Influences Performance of Encapsulated Live Biotherapeutic Products.	Qiu K, Huang Y, Anselmo AC	Cell Mol Bioeng	10.1007/s12195-021-00674-z	2021
	Anticancer Activity of Biogenic Selenium Nanoparticles: Apoptotic and Immunogenic Cell Death Markers in Colon Cancer Cells.	Spyridopoulou K, Aindelis G, Pappa A, Chlichlia K	Cancers (Basel)	10.3390/cancers13215335	2021
Metabolism	Lactobacillus casei ATCC 393 and it's metabolites alleviate dextran sulphate sodium-induced ulcerative colitis in mice through the NLRP3-(Caspase-1)/IL-1beta pathway.	Dou X, Qiao L, Chang J, Yan S, Song X, Chen Y, Xu Q, Xu C	Food Funct	10.1039/d1fo02405a	2021
	Alterations in Faecal Microbiota and Elevated Levels of Intestinal IgA Following Oral Administration of Lacticaseibacillus casei in mice.	Aindelis G, Ypsilantis P, Chlichlia K	Probiotics Antimicrob Proteins	10.1007/s12602-021-09864-7	2021
Phylogeny	Isolation and Characterization of Membrane Vesicles from Lactobacillus Species.	Caruana JC, Dean SN, Walper SA	Bio Protoc	10.21769/BioProtoc.4145	2021
	Development and Optimization of Djulis Sourdough Bread Fermented by Lactic Acid Bacteria for Antioxidant Capacity.	Chen HY, Hsieh CW, Chen PC, Lin SP, Lin YF, Cheng KC	Molecules	10.3390/molecules26185658	2021
Pathogenicity	Tailored synbiotic powder (functional food) to prevent hyperphosphataemia (kidney disorder).	Anand A, Yoshida S, Aoyagi H	Sci Rep	10.1038/s41598-021-95176-3	2021
	Oral Immunization with Lactobacillus casei Expressing the Porcine Circovirus Type 2 Cap and LTB Induces Mucosal and Systemic Antibody Responses in Mice.	Li F, Wang X, Ma R, Wu W, Teng F, Cheng X, Jiang Y, Zhou H, Wang L, Tang L, Qiao X, Li Y	Viruses	10.3390/v13071302	2021
Pathogenicity	Biogenic selenium nanoparticles by Lactobacillus casei ATCC 393 alleviate the intestinal permeability, mitochondrial dysfunction and mitophagy induced by oxidative stress.	Yan S, Qiao L, Dou X, Song X, Chen Y, Zhang B, Xu C	Food Funct	10.1039/d0fo03141k	2021
	Encapsulation of Lactobacillus in Low-Methoxyl Pectin-Based Microcapsules Stimulates Biofilm Formation: Enhanced Resistances to Heat Shock and Simulated Gastrointestinal Digestion.	He C, Sampers I, Van de Walle D, Dewettinck K, Raes K	J Agric Food Chem	10.1021/acs.jafc.1c00719	2021
	Microencapsulation of Lactobacillus casei and Lactobacillus rhamnosus in pectin and pectin-inulin microgel particles: Effect on bacterial survival under storage conditions.	Tarifa MC, Piqueras CM, Genovese DB, Brugnoni LI	Int J Biol Macromol	10.1016/j.ijbiomac.2021.03.038	2021
Phylogeny	Genome-based reclassification of Lactobacillus casei: emended classification and description of the species Lactobacillus zeae.	Huang CH, Chen CC, Liou JS, Lee AY, Blom J, Lin YC, Huang L, Watanabe K	Int J Syst Evol Microbiol	10.1099/ijsem.0.003969	2020
Pathogenicity	Biogenic selenium nanoparticles synthesized by Lactobacillus casei ATCC 393 alleviate diquat-induced intestinal barrier dysfunction in C57BL/6 mice through their antioxidant activity.	Qiao L, Dou X, Yan S, Zhang B, Xu C	Food Funct	10.1039/d0fo00132e	2020
	Polymeric Films for the Encapsulation, Storage, and Tunable Release of Therapeutic Microbes.	Qiu K, Young I, Woodburn BM, Huang Y, Anselmo AC	Adv Healthc Mater	10.1002/adhm.201901643	2020
Metabolism	Lactobacillus casei ATCC 393 alleviates Enterotoxigenic Escherichia coli K88-induced intestinal barrier dysfunction via TLRs/mast cells pathway.	Xu C, Yan S, Guo Y, Qiao L, Ma L, Dou X, Zhang B	Life Sci	10.1016/j.lfs.2020.117281	2020
	Enhanced Aromatic Profile and Functionality of Cheese Whey Beverages by Incorporation of Probiotic Cells Immobilized on Pistacia terebinthus Resin.	Schoina V, Terpou A, Papadaki A, Bosnea L, Kopsahelis N, Kanellaki M	Foods	10.3390/foods9010013	2019
Phylogeny	A High Throughput Isolation Method for Phosphate-Accumulating Organisms.	Anand A, Aoyagi H	Sci Rep	10.1038/s41598-019-53429-2	2019
Cultivation	Topical Delivery of Lactobacillus Culture Supernatant Increases Survival and Wound Resolution in Traumatic Acinetobacter baumannii Infections.	Stanbro J, Park JM, Bond M, Stockelman MG, Simons MP, Watters C	Probiotics Antimicrob Proteins	10.1007/s12602-019-09603-z	2020
Metabolism	Exploring encapsulation strategies as a protective mechanism to avoid amensalism in mixed populations of Pseudomonas taetrolens and Lactobacillus casei.	Garcia C, Ranieri G, Rendueles M, Diaz M	Bioprocess Biosyst Eng	10.1007/s00449-019-02204-8	2019
	Assessment of Freeze-Dried Immobilized Lactobacillus casei as Probiotic Adjunct Culture in Yogurts.	Dimitrellou D, Kandylis P, Kourkoutas Y	Foods	10.3390/foods8090374	2019
	Effect of Milk Type on the Microbiological, Physicochemical and Sensory Characteristics of Probiotic Fermented Milk.	Dimitrellou D, Salamoura C, Kontogianni A, Katsipi D, Kandylis P, Zakynthinos G, Varzakas T	Microorganisms	10.3390/microorganisms7090274	2019
Pathogenicity	Biogenic selenium nanoparticles synthesized by Lactobacillus casei ATCC 393 alleviate intestinal epithelial barrier dysfunction caused by oxidative stress via Nrf2 signaling-mediated mitochondrial pathway.	Xu C, Qiao L, Ma L, Guo Y, Dou X, Yan S, Zhang B, Roman A	Int J Nanomedicine	10.2147/IJN.S199193	2019
	Recombinant l-Asparaginase II from Lactobacillus casei subsp. casei ATCC 393 and Its Anticancer Activity.	Aishwarya SS, Selvarajan E, Iyappan S, Rajnish KN	Indian J Microbiol	10.1007/s12088-019-00806-0	2019
	Effect of Sugar Content on Quality Characteristics and Shelf-Life of Probiotic Dry-Fermented Sausages Produced by Free or Immobilized Lactobacillus casei ATCC 393.	Sidira M, Mitropoulou G, Galanis A, Kanellaki M, Kourkoutas Y	Foods	10.3390/foods8060219	2019
Metabolism	Estimation of microbial phosphate-accumulation abilities.	Anand A, Aoyagi H	Sci Rep	10.1038/s41598-018-37752-8	2019
	Genetic Signatures of Dairy Lactobacillus casei Group.	Fontana A, Zacconi C, Morelli L	Front Microbiol	10.3389/fmicb.2018.02611	2018
Pathogenicity	Lactobacillus paracasei K5 displays adhesion, anti-proliferative activity and apoptotic effects in human colon cancer cells.	Chondrou P, Karapetsas A, Kiousi DE, Tsela D, Tiptiri-Kourpeti A, Anestopoulos I, Kotsianidis I, Bezirtzoglou E, Pappa A, Galanis A	Benef Microbes	10.3920/BM2017.0183	2018
Metabolism	Construction of Lactobacillus casei ghosts by Holin-mediated inactivation and the potential as a safe and effective vehicle for the delivery of DNA vaccines.	Hou R, Li M, Tang T, Wang R, Li Y, Xu Y, Tang L, Wang L, Liu M, Jiang Y, Cui W, Qiao X	BMC Microbiol	10.1186/s12866-018-1216-6	2018
	Biogenic Synthesis of Novel Functionalized Selenium Nanoparticles by Lactobacillus casei ATCC 393 and Its Protective Effects on Intestinal Barrier Dysfunction Caused by Enterotoxigenic Escherichia coli K88.	Xu C, Guo Y, Qiao L, Ma L, Cheng Y, Roman A	Front Microbiol	10.3389/fmicb.2018.01129	2018
Pathogenicity	Preparation, characteristics and antioxidant activity of polysaccharides and proteins-capped selenium nanoparticles synthesized by Lactobacillus casei ATCC 393.	Xu C, Qiao L, Guo Y, Ma L, Cheng Y	Carbohydr Polym	10.1016/j.carbpol.2018.04.110	2018
Metabolism	Adsorption preference for divalent metal ions by Lactobacillus casei JCM1134.	Endo R, Aoyagi H	Appl Microbiol Biotechnol	10.1007/s00253-018-9050-1	2018
Pathogenicity	Probiotic Lactobacillus sp. inhibit growth, biofilm formation and gene expression of caries-inducing Streptococcus mutans.	Wasfi R, Abd El-Rahman OA, Zafer MM, Ashour HM	J Cell Mol Med	10.1111/jcmm.13496	2018
	Soybean protein-based microparticles for oral delivery of probiotics with improved stability during storage and gut resistance.	Gonzalez-Ferrero C, Irache JM, Gonzalez-Navarro CJ	Food Chem	10.1016/j.foodchem.2017.07.022	2017
Metabolism	Recombinant Lactobacillus casei expressing Clostridium perfringens toxoids alpha, beta2, epsilon and beta1 gives protection against Clostridium perfringens in rabbits.	Zhao L, Guo Z, Liu J, Wang Z, Wang R, Li Y, Wang L, Xu Y, Tang L, Qiao X	Vaccine	10.1016/j.vaccine.2017.05.076	2017
Enzymology	A Recombinant Probiotic, Lactobacillus casei, Expressing the Clostridium perfringens alpha-toxoid, as an Orally Vaccine Candidate Against Gas Gangrene and Necrotic Enteritis.	Alimolaei M, Golchin M, Abshenas J, Ezatkhah M, Bafti MS	Probiotics Antimicrob Proteins	10.1007/s12602-017-9276-8	2018
Pathogenicity	Protective Effect of Lactobacillus casei on DMH-Induced Colon Carcinogenesis in Mice.	Irecta-Najera CA, Del Rosario Huizar-Lopez M, Casas-Solis J, Castro-Felix P, Santerre A	Probiotics Antimicrob Proteins	10.1007/s12602-017-9253-2	2017
Pathogenicity	Prophylactic Effect of Lactobacillus pentosus strain S-PT84 on Candida Infection and Gastric Inflammation in a Murine Gastrointestinal Candidiasis Model [Errata].	Maekawa T, Ishijima AS, Ida M, Izumo T, Ono Y, Shibata H, Abe S	Med Mycol J	10.3314/mmj.16-00012E	2016
Pathogenicity	Prophylactic Effect of Lactobacillus pentosus strain S-PT84 on Candida Infection and Gastric Inflammation in a Murine Gastrointestinal Candidiasis Model.	Maekawa T, Ishijima AS, Ida M, Izumo T, Ono Y, Shibata H, Abe S	Med Mycol J	10.3314/mmj.16-00012	2016
	Directed chromosomal integration and expression of porcine rotavirus outer capsid protein VP4 in Lactobacillus casei ATCC393.	Yin JY, Guo CQ, Wang Z, Yu ML, Gao S, Bukhari SM, Tang LJ, Xu YG, Li YJ	Appl Microbiol Biotechnol	10.1007/s00253-016-7779-y	2016
Metabolism	Lactobacillus pentosus expressing porcine lactoferrin elevates antibacterial activity and improves the efficacy of vaccination against Aujeszky's disease.	Xu Y, Zong X, Han B, Li Y, Tang L	Acta Vet Hung	10.1556/004.2016.028	2016
	Orally Administered Salacia reticulata Extract Reduces H1N1 Influenza Clinical Symptoms in Murine Lung Tissues Putatively Due to Enhanced Natural Killer Cell Activity.	Romero-Perez GA, Egashira M, Harada Y, Tsuruta T, Oda Y, Ueda F, Tsukahara T, Tsukamoto Y, Inoue R	Front Immunol	10.3389/fimmu.2016.00115	2016
Pathogenicity	Effect of oligosaccharides on the adhesion of gut bacteria to human HT-29 cells.	Altamimi M, Abdelhay O, Rastall RA	Anaerobe	10.1016/j.anaerobe.2016.03.010	2016
	Effect of curing salts and probiotic cultures on the evolution of flavor compounds in dry-fermented sausages during ripening.	Sidira M, Kandylis P, Kanellaki M, Kourkoutas Y	Food Chem	10.1016/j.foodchem.2016.01.084	2016
Metabolism	Lactobacillus casei Exerts Anti-Proliferative Effects Accompanied by Apoptotic Cell Death and Up-Regulation of TRAIL in Colon Carcinoma Cells.	Tiptiri-Kourpeti A, Spyridopoulou K, Santarmaki V, Aindelis G, Tompoulidou E, Lamprianidou EE, Saxami G, Ypsilantis P, Lampri ES, Simopoulos C, Kotsianidis I, Galanis A, Kourkoutas Y, Dimitrellou D, Chlichlia K	PLoS One	10.1371/journal.pone.0147960	2016
	In vitro study on the cell adhesion ability of immobilized lactobacilli on natural supports.	Sidira M, Kourkoutas Y, Kanellaki M, Charalampopoulos D	Food Res Int	10.1016/j.foodres.2015.07.036	2015
	Use of Pistacia terebinthus resin as immobilization support for Lactobacillus casei cells and application in selected dairy products.	Schoina V, Terpou A, Angelika-Ioanna G, Koutinas A, Kanellaki M, Bosnea L	J Food Sci Technol	10.1007/s13197-014-1627-9	2014
Biotechnology	Effect of refrigerated storage on probiotic viability and the production and stability of antimutagenic and antioxidant peptides in yogurt supplemented with pineapple peel.	Sah BN, Vasiljevic T, McKechnie S, Donkor ON	J Dairy Sci	10.3168/jds.2015-9450	2015
Enzymology	Isolation and Characterization of a Novel Virulent Phage of Lactobacillus casei ATCC 393.	Zhang X, Lan Y, Jiao W, Li Y, Tang L, Jiang Y, Cui W, Qiao X	Food Environ Virol	10.1007/s12560-015-9206-4	2015
Metabolism	Secretory expression of a phospholipase A2 from Lactobacillus casei DSM20011 in Kluyveromyces lactis.	Wang H, Zhang L, Shi G	J Biosci Bioeng	10.1016/j.jbiosc.2015.03.022	2015
Metabolism	[Comparison of expression and antibacterial activities of recombinant porcine lactoferrin expressed in four Lactobacillus species].	Yu H, Jiang Y, Cui W, Wu X, He J, Qiao X, Li Y, Tang L	Sheng Wu Gong Cheng Xue Bao		2014
Stress	Effect of immobilized Lactobacillus casei on volatile compounds of heat treated probiotic dry-fermented sausages.	Sidira M, Kandylis P, Kanellaki M, Kourkoutas Y	Food Chem	10.1016/j.foodchem.2015.01.068	2015
Metabolism	C/EBPalpha controls mast cell function.	Kasakura K, Takahashi K, Itoh T, Hosono A, Nunomura S, Ra C, Momose Y, Itoh K, Nishiyama C, Kaminogawa S	FEBS Lett	10.1016/j.febslet.2014.10.036	2014
Biotechnology	Effect of immobilized Lactobacillus casei on the evolution of flavor compounds in probiotic dry-fermented sausages during ripening.	Sidira M, Kandylis P, Kanellaki M, Kourkoutas Y	Meat Sci	10.1016/j.meatsci.2014.09.011	2014
Biotechnology	Free and immobilized Lactobacillus casei ATCC 393 on whey protein as starter cultures for probiotic Feta-type cheese production.	Dimitrellou D, Kandylis P, Sidira M, Koutinas AA, Kourkoutas Y	J Dairy Sci	10.3168/jds.2013-7597	2014
Genetics	Construction of upp deletion mutant strains of Lactobacillus casei and Lactococcus lactis based on counterselective system using temperature-sensitive plasmid.	Song L, Cui H, Tang L, Qiao X, Liu M, Jiang Y, Cui W, Li Y	J Microbiol Methods	10.1016/j.mimet.2014.04.011	2014
	Chromosomal insertions in the Lactobacillus casei upp gene that are useful for vaccine expression.	Song BF, Ju LZ, Li YJ, Tang LJ	Appl Environ Microbiol	10.1128/AEM.00175-14	2014
Enzymology	Effective survival of immobilized Lactobacillus casei during ripening and heat treatment of probiotic dry-fermented sausages and investigation of the microbial dynamics.	Sidira M, Karapetsas A, Galanis A, Kanellaki M, Kourkoutas Y	Meat Sci	10.1016/j.meatsci.2013.09.013	2013
Enzymology	16S rRNA PCR-Denaturing Gradient Gel Electrophoresis of Oral Lactobacillus casei Group and Their Phenotypic Appearances.	Piwat S, Teanpaisan R	ISRN Microbiol	10.1155/2013/342082	2013
Genetics	Genomic adaptation of the Lactobacillus casei group.	Toh H, Oshima K, Nakano A, Takahata M, Murakami M, Takaki T, Nishiyama H, Igimi S, Hattori M, Morita H	PLoS One	10.1371/journal.pone.0075073	2013
Metabolism	Growth inhibition of hepatocellular carcinoma Huh7 cells by Lactobacillus casei extract.	Han DJ, Kim JB, Park SY, Yang MG, Kim H	Yonsei Med J	10.3349/ymj.2013.54.5.1186	2013
Metabolism	Increase of the adhesion ability and display of a rumen fungal xylanase on the cell surface of Lactobacillus casei by using a listerial cell-wall-anchoring protein.	Hsueh HY, Yu B, Liu CT, Liu JR	J Sci Food Agric	10.1002/jsfa.6298	2013
	Monitoring survival of Lactobacillus casei ATCC 393 in probiotic yogurts using an efficient molecular tool.	Sidira M, Saxami G, Dimitrellou D, Santarmaki V, Galanis A, Kourkoutas Y	J Dairy Sci	10.3168/jds.2012-6343	2013
Metabolism	Use of Lactobacillus acidophilus and Lactobacillus casei for a potential probiotic legume-based fermented product using pigeon pea (Cajanus cajan).	Parra K, Ferrer M, Pinero M, Barboza Y, Medina LM	J Food Prot	10.4315/0362-028X.JFP-12-138	2013
Phylogeny	Characterization of the Lactobacillus casei group based on the profiling of ribosomal proteins coded in S10-spc-alpha operons as observed by MALDI-TOF MS.	Sato H, Torimura M, Kitahara M, Ohkuma M, Hotta Y, Tamura H	Syst Appl Microbiol	10.1016/j.syapm.2012.08.008	2012
	The effects of microencapsulated Lactobacillus casei on tumour cell growth: In vitro and in vivo studies.	Dwivedi A, Nomikou N, Nigam PS, McHale AP	Int J Med Microbiol	10.1016/j.ijmm.2012.09.002	2012
Enzymology	Stable integration and expression of heterologous genes in several lactobacilli using an integration vector constructed from the integrase and attP sequences of phage PhiAT3 isolated from Lactobacillus casei ATCC 393.	Lin CF, Lo TC, Kuo YC, Lin TH	Appl Microbiol Biotechnol	10.1007/s00253-012-4393-5	2012
Stress	Investigation of Shelf Life of Potency and Activity of the Lactobacilli Produced Bacteriocins Through Their Exposure to Various Physicochemical Stress Factors.	Zacharof MP, Lovitt RW	Probiotics Antimicrob Proteins	10.1007/s12602-012-9102-2	2012
Pathogenicity	Growth-inhibiting effects of Paeonia lactiflora root steam distillate constituents and structurally related compounds on human intestinal bacteria.	Ngan LT, Moon JK, Kim JH, Shibamoto T, Ahn YJ	World J Microbiol Biotechnol	10.1007/s11274-011-0961-6	2011
	Distinct adhesion of probiotic strain Lactobacillus casei ATCC 393 to rat intestinal mucosa.	Saxami G, Ypsilantis P, Sidira M, Simopoulos C, Kourkoutas Y, Galanis A	Anaerobe	10.1016/j.anaerobe.2012.04.002	2012
Metabolism	Effect of cellooligosaccharide or synbiotic feeding on growth performance, fecal condition and hormone concentrations in Holstein calves.	Hasunuma T, Kawashima K, Nakayama H, Murakami T, Kanagawa H, Ishii T, Akiyama K, Yasuda K, Terada F, Kushibiki S	Anim Sci J	10.1111/j.1740-0929.2010.00861.x	2011
Metabolism	Effect of probiotic-fermented milk administration on gastrointestinal survival of Lactobacillus casei ATCC 393 and modulation of intestinal microbial flora.	Sidira M, Galanis A, Ypsilantis P, Karapetsas A, Progaki Z, Simopoulos C, Kourkoutas Y	J Mol Microbiol Biotechnol	10.1159/000321115	2010
Metabolism	Expression of Lactobacillus reuteri Pg4 collagen-binding protein gene in Lactobacillus casei ATCC 393 increases its adhesion ability to Caco-2 cells.	Hsueh HY, Yueh PY, Yu B, Zhao X, Liu JR	J Agric Food Chem	10.1021/jf1035756	2010
Pathogenicity	The influence of some probiotic supernatants on the growth and virulence features expression of several selected enteroaggregative E. coli clinical strains.	Lazar V, Miyazaki Y, Hanawa T, Chifiriuc MC, Ditu LM, Marutescu L, Bleotu C, Kamiya S	Roum Arch Microbiol Immunol		2009
Pathogenicity	[Influence of cross-protection on the survival of Lactobacillus casei ATCC 393].	Xue F, Zhang J, Du G, Chen J	Wei Sheng Wu Xue Bao		2010
Pathogenicity	Rapid detection and identification of probiotic Lactobacillus casei ATCC 393 by multiplex PCR.	Karapetsas A, Vavoulidis E, Galanis A, Sandaltzopoulos R, Kourkoutas Y	J Mol Microbiol Biotechnol	10.1159/000308518	2010
Metabolism	Effect of prebiotics on viability and growth characteristics of probiotics in soymilk.	Yeo SK, Liong MT	J Sci Food Agric	10.1002/jsfa.3808	2010
Enzymology	Construction of recombinant Lactobacillus casei strains using splicing by overlap extension.	Jeong DW, Lee JH, Lee HJ	J Microbiol Biotechnol	8152	2008
Pathogenicity	Antibacterial effects of three experimental quaternary ammonium salt (QAS) monomers on bacteria associated with oral infections.	Xiao YH, Chen JH, Fang M, Xing XD, Wang H, Wang YJ, Li F	J Oral Sci	10.2334/josnusd.50.323	2008
	Microencapsulation of a probiotic bacteria with alginate-gelatin and its properties.	Li XY, Chen XG, Cha DS, Park HJ, Liu CS	J Microencapsul	10.1080/02652040802328685	2008
Phylogeny	The type strain of Lactobacillus casei is ATCC 393, ATCC 334 cannot serve as the type because it represents a different taxon, the name Lactobacillus paracasei and its subspecies names are not rejected and the revival of the name 'Lactobacillus zeae' contravenes Rules 51b (1) and (2) of the International Code of Nomenclature of Bacteria. Opinion 82.		Int J Syst Evol Microbiol	10.1099/ijs.0.2008/005330-0	2008
Pathogenicity	Fluoride release and antibacterial activity of selected dental materials.	Marczuk-Kolada G, Jakoniuk P, Mystkowska J, Luczaj-Cepowicz E, Waszkiel D, Dabrowski JR, Leszczynska K	Postepy Hig Med Dosw (Online)	453293	2006
Phylogeny	Taxonomic and strain-specific identification of the probiotic strain Lactobacillus rhamnosus 35 within the Lactobacillus casei group.	Coudeyras S, Marchandin H, Fajon C, Forestier C	Appl Environ Microbiol	10.1128/AEM.02286-07	2008
	Construction of recombinant Lactobacillus casei efficiently surface displayed and secreted porcine parvovirus VP2 protein and comparison of the immune responses induced by oral immunization.	Yigang XU, Yijing LI	Immunology	10.1111/j.1365-2567.2007.02738.x	2007
Pathogenicity	Incorporation of citrus fibers in fermented milk containing probiotic bacteria.	Sendra E, Fayos P, Lario Y, Fernandez-Lopez J, Sayas-Barbera E, Perez-Alvarez JA	Food Microbiol	10.1016/j.fm.2007.09.003	2007
Metabolism	Induction of immune responses in mice after intragastric administration of Lactobacillus casei producing porcine parvovirus VP2 protein.	Xu Y, Li Y	Appl Environ Microbiol	10.1128/AEM.00436-07	2007
Phylogeny	Multilocus sequence typing of Lactobacillus casei reveals a clonal population structure with low levels of homologous recombination.	Diancourt L, Passet V, Chervaux C, Garault P, Smokvina T, Brisse S	Appl Environ Microbiol	10.1128/AEM.01095-07	2007
Metabolism	Arsenic removal by native and chemically modified lactic acid bacteria.	Halttunen T, Finell M, Salminen S	Int J Food Microbiol	10.1016/j.ijfoodmicro.2007.06.002	2007
	Impact of lactic Acid bacteria on dendritic cells from allergic patients in an experimental model of intestinal epithelium.	Ratajczak C, Duez C, Grangette C, Pochard P, Tonnel AB, Pestel J	J Biomed Biotechnol	10.1155/2007/71921	2007
Pathogenicity	Antibacterial activities of inorganic agents on six bacteria associated with oral infections by two susceptibility tests.	Fang M, Chen JH, Xu XL, Yang PH, Hildebrand HF	Int J Antimicrob Agents	10.1016/j.ijantimicag.2006.01.008	2006
Pathogenicity	Effects of Lactobacillus strains on cancer cell proliferation and oxidative stress in vitro.	Choi SS, Kim Y, Han KS, You S, Oh S, Kim SH	Lett Appl Microbiol	10.1111/j.1472-765X.2006.01913.x	2006
Phylogeny	Ribotyping of Lactobacillus casei group strains isolated from dairy products.	Svec P, Drab V, Sedlacek I	Folia Microbiol (Praha)	10.1007/BF02931570	2005
Phylogeny	DNA-based classification and sequence heterogeneities in the 16S rRNA genes of Lactobacillus casei/paracasei and related species.	Vasquez A, Molin G, Pettersson B, Antonsson M, Ahrne S	Syst Appl Microbiol	10.1016/j.syapm.2005.02.011	2005
Genetics	Complete genomic sequence of the temperate bacteriophage PhiAT3 isolated from Lactobacillus casei ATCC 393.	Lo TC, Shih TC, Lin CF, Chen HW, Lin TH	Virology	10.1016/j.virol.2005.05.022	2005
Metabolism	Malolactic fermentation in wine with Lactobacillus casei cells immobilized on Delignified cellulosic material.	Agouridis N, Bekatorou A, Nigam P, Kanellaki M	J Agric Food Chem	10.1021/jf048736t	2005
Enzymology	Cell wall modifications during osmotic stress in Lactobacillus casei.	Piuri M, Sanchez-Rivas C, Ruzal SM	J Appl Microbiol	10.1111/j.1365-2672.2004.02428.x	2005
Phylogeny	Lactobacillus casei, Lactobacillus rhamnosus, and Lactobacillus zeae isolates identified by sequence signature and immunoblot phenotype.	Dobson CM, Chaban B, Deneer H, Ziola B	Can J Microbiol	10.1139/w04-044	2004
Biotechnology	Nisin-controlled expression of Norwalk virus VP60 protein in Lactobacillus casei.	Martin MC, Fernandez M, Martin-Alonso JM, Parra F, Boga JA, Alvarez MA	FEMS Microbiol Lett	10.1016/j.femsle.2004.07.002	2004
Cultivation	Osmotic response in Lactobacillus casei ATCC 393: biochemical and biophysical characteristics of membrane.	Machado MC, Lopez CS, Heras H, Rivas EA	Arch Biochem Biophys	10.1016/j.abb.2003.11.001	2004
Genetics	Homology modeling of the central catalytic domain of insertion sequence ISLC3 isolated from Lactobacillus casei ATCC 393.	Lin TH, Tsai KC, Lo TC	Protein Eng	10.1093/protein/gzg107	2003
Phylogeny	Significant differences between Lactobacillus casei subsp. casei ATCC 393T and a commonly used plasmid-cured derivative revealed by a polyphasic study.	Acedo-Felix E, Perez-Martinez G	Int J Syst Evol Microbiol	10.1099/ijs.0.02325-0	2003
Phylogeny	The status of the species Lactobacillus casei (Orla-Jensen 1916) Hansen and Lessel 1971 and Lactobacillus paracasei Collins et al. 1989. Request for an opinion.	Dellaglio F, Felis GE, Torriani S	Int J Syst Evol Microbiol	10.1099/00207713-52-1-285	2002
Phylogeny	Comparative sequence analysis of a recA gene fragment brings new evidence for a change in the taxonomy of the Lactobacillus casei group.	Felis GE, Dellaglio F, Mizzi L, Torriani S	Int J Syst Evol Microbiol	10.1099/00207713-51-6-2113	2001
Phylogeny	Characterization of the Lactobacillus casei group and the Lactobacillus acidophilus group by automated ribotyping.	Ryu CS, Czajka JW, Sakamoto M, Benno Y	Microbiol Immunol	10.1111/j.1348-0421.2001.tb02618.x	2001
Metabolism	Expression of cbsA encoding the collagen-binding S-protein of Lactobacillus crispatus JCM5810 in Lactobacillus casei ATCC 393(T).	Martinez B, Sillanpaa J, Smit E, Korhonen TK, Pouwels PH	J Bacteriol	10.1128/JB.182.23.6857-6861.2000	2000
Biotechnology	Generation of food-grade recombinant lactic acid bacterium strains by site-specific recombination.	Martin MC, Alonso JC, Suarez JE, Alvarez MA	Appl Environ Microbiol	10.1128/AEM.66.6.2599-2604.2000	2000
Phylogeny	Comparative analysis of the genes encoding 23S-5S rRNA intergenic spacer regions of Lactobacillus casei-related strains.	Chen H, Lim CK, Lee YK, Chan YN	Int J Syst Evol Microbiol	10.1099/00207713-50-2-471	2000
Metabolism	Genetics of L-sorbose transport and metabolism in Lactobacillus casei.	Yebra MJ, Veyrat A, Santos MA, Perez-Martinez G	J Bacteriol	10.1128/JB.182.1.155-163.2000	2000
Metabolism	Enhanced production of L-(+)-lactic acid in chemostat by Lactobacillus casei DSM 20011 using ion-exchange resins and cross-flow filtration in a fully automated pilot plant controlled via NIR.	Gonzalez-Vara Y R A, Vaccari G, Dosi E, Trilli A, Rossi M, Matteuzzi D	Biotechnol Bioeng	10.1002/(SICI)1097-0290(20000120)67:2<147::AID-BIT4>3.0.CO;2-F	2000
Phylogeny	Comparison of ribotyping, randomly amplified polymorphic DNA analysis, and pulsed-field gel electrophoresis in typing of Lactobacillus rhamnosus and L. casei strains.	Tynkkynen S, Satokari R, Saarela M, Mattila-Sandholm T, Saxelin M	Appl Environ Microbiol	10.1128/AEM.65.9.3908-3914.1999	1999
Enzymology	Transport of D-xylose in Lactobacillus pentosus, Lactobacillus casei, and Lactobacillus plantarum: evidence for a mechanism of facilitated diffusion via the phosphoenolpyruvate:mannose phosphotransferase system.	Chaillou S, Pouwels PH, Postma PW	J Bacteriol	10.1128/JB.181.16.4768-4773.1999	1999
Metabolism	Elements involved in catabolite repression and substrate induction of the lactose operon in Lactobacillus casei.	Gosalbes MJ, Monedero V, Perez-Martinez G	J Bacteriol	10.1128/JB.181.13.3928-3934.1999	1999
Biotechnology	Stable expression of the Lactobacillus casei bacteriophage A2 repressor blocks phage propagation during milk fermentation.	Alvarez MA, Rodriguez A, Suarez JE	J Appl Microbiol	10.1046/j.1365-2672.1999.00728.x	1999
Enzymology	Catabolite repression in Lactobacillus casei ATCC 393 is mediated by CcpA.	Monedero V, Gosalbes MJ, Perez-Martinez G	J Bacteriol	10.1128/jb.179.21.6657-6664.1997	1997
Metabolism	Peptidoglycan structure of Lactobacillus casei, a species highly resistant to glycopeptide antibiotics.	Billot-Klein D, Legrand R, Schoot B, van Heijenoort J, Gutmann L	J Bacteriol	10.1128/jb.179.19.6208-6212.1997	1997
Genetics	Establishing a model to study the regulation of the lactose operon in Lactobacillus casei.	Gosalbes MJ, Monedero V, Alpert CA, Perez-Martinez G	FEMS Microbiol Lett	10.1111/j.1574-6968.1997.tb10271.x	1997
Phylogeny	Reclassification of Lactobacillus casei subsp. casei ATCC 393 and Lactobacillus rhamnosus ATCC 15820 as Lactobacillus zeae nom. rev., designation of ATCC 334 as the neotype of L. casei subsp. casei, and rejection of the name Lactobacillus paracasei.	Dicks LM, Du Plessis EM, Dellaglio F, Lauer E	Int J Syst Bacteriol	10.1099/00207713-46-1-337	1996
Enzymology	Expression of Lactobacillus casei ATCC 393 beta-galactosidase encoded by plasmid pLZ15 in Lactococcus lactis CNRZ 1123.	Hemme D, Gaier W, Winters DA, Foucaud C, Vogel RF	Lett Appl Microbiol	10.1111/j.1472-765x.1994.tb00471.x	1994
Metabolism	Glucose transport by the phosphoenolpyruvate:mannose phosphotransferase system in Lactobacillus casei ATCC 393 and its role in carbon catabolite repression.	Veyrat A, Monedero V, Perez-Martinez G	Microbiology (Reading)	10.1099/13500872-140-5-1141	1994
Genetics	Structural and functional analysis of two cryptic plasmids from Lactobacillus pentosus MD353 and Lactobacillus plantarum ATCC 8014.	Leer RJ, van Luijk N, Posno M, Pouwels PH	Mol Gen Genet	10.1007/BF00283847	1992
Enzymology	Cloning and nucleotide sequence of the Lactobacillus casei lactate dehydrogenase gene.	Kim SF, Baek SJ, Pack MY	Appl Environ Microbiol	10.1128/aem.57.8.2413-2417.1991	1991
Cultivation	Microbial caries induction in the roots of human teeth in vitro.	Kaufman HW, Pollock JJ, Gwinnett AJ	Arch Oral Biol	10.1016/0003-9969(88)90031-3	1988
Enzymology	Proteolytic activity of crude cell-free extract of Lactobacillus casei and Lactobacillus plantarum.	Hegazi FZ, Abo-Elnaga IG	Nahrung	10.1002/food.19870310309	1987
Enzymology	Comparative studies of lactic acid dehydrogenases in lactic acid bacteria. I. Purification and kinetics of the allosteric L-lactic acid dehydrogenase from Lactobacillus casei ssp. casei and Lactobacillus curvatus.	Hensel R, Mayr U, Stetter KO, Kandler O	Arch Microbiol	10.1007/BF00446658	1977
Enzymology	Purification, properties and immunological relationship of L (+)-lactate dehydrogenase from Lactobacillus casei.	Gordon GL, Doelle HW	Eur J Biochem	10.1111/j.1432-1033.1976.tb10720.x	1976
Metabolism	Effects of citrate on the composition and metabolism of Lactobacillus casei.	Branen AL, Keenan TW	Appl Microbiol	10.1128/am.21.6.993-998.1971	1971
	Biogenic Selenium Nanoparticles Synthesized by Lactobacillus casei ATCC 393 Alleviate Acute Hypobaric Hypoxia-Induced Intestinal Barrier Dysfunction in C57BL/6 Mice.	Dou X, Zhang B, Qiao L, Song X, Pi S, Chang J, Zhang X, Zeng X, Zhu L, Xu C	Biol Trace Elem Res	10.1007/s12011-022-03513-y	2022
	Biogenic Selenium Nanoparticles Attenuate Abeta(25-35)-Induced Toxicity in PC12 Cells via Akt/CREB/BDNF Signaling Pathway.	Qiao L, Chen Y, Dou X, Song X, Xu C	Neurotox Res	10.1007/s12640-022-00590-8	2022
Metabolism	Dietary supplementation with selenium nanoparticles-enriched Lactobacillus casei ATCC 393 alleviates intestinal barrier dysfunction of mice exposed to deoxynivalenol by regulating endoplasmic reticulum stress and gut microbiota.	Song X, Qiao L, Chang J, Dou X, Zhang X, Pi S, Xu C	Ecotoxicol Environ Saf	10.1016/j.ecoenv.2022.114276	2022
Metabolism	Selenium Nanoparticles-Enriched Lactobacillus casei ATCC 393 Prevents Cognitive Dysfunction in Mice Through Modulating Microbiota-Gut-Brain Axis.	Qiao L, Chen Y, Song X, Dou X, Xu C	Int J Nanomedicine	10.2147/IJN.S374024	2022
	Biogenic selenium nanoparticles produced by Lactobacillus casei ATCC 393 inhibit colon cancer cell growth in vitro and in vivo.	Spyridopoulou K, Tryfonopoulou E, Aindelis G, Ypsilantis P, Sarafidis C, Kalogirou O, Chlichlia K	Nanoscale Adv	10.1039/d0na00984a	2021
Phylogeny	Lacticaseibacillus parahuelsenbergensis sp. nov., Lacticaseibacillus styriensis sp. nov. and Lacticaseibacillus zeae subsp. silagei subsp. nov., isolated from different grass and corn silage.	Grabner F M, Grabner H M, Schein H, Schrank A, Toglhofer M, Weidenholzer E, Ruckert-Reed C, Busche T, Buchebner-Jance M.	Int J Syst Evol Microbiol	10.1099/ijsem.0.006441	2024
Phylogeny	Lactobacillus brantae sp. nov., isolated from faeces of Canada geese (Branta canadensis).	Volokhov DV, Amselle M, Beck BJ, Popham DL, Whittaker P, Wang H, Kerrigan E, Chizhikov VE	Int J Syst Evol Microbiol	10.1099/ijs.0.033852-0	2011

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#68379	Automatically annotated from API Coryne .
#68382	Automatically annotated from API zym .
#69479	João F Matias Rodrigues, Janko Tackmann,Gregor Rot, Thomas SB Schmidt, Lukas Malfertheiner, Mihai Danaila,Marija Dmitrijeva, Daniela Gaio, Nicolas Näpflin and Christian von Mering. University of Zurich.: MicrobeAtlas 1.0 beta .
#117199	Collection of Institut Pasteur ; Curators of the CIP; CIP 103137
#125438	Julia Koblitz, Lorenz Christian Reimer, Rüdiger Pukall, Jörg Overmann: Predicting bacterial phenotypic traits through improved machine learning using high-quality, curated datasets. 2024 ( DOI 10.1101/2024.08.12.607695 )
#125439	Philipp Münch, René Mreches, Martin Binder, Hüseyin Anil Gündüz, Xiao-Yin To, Alice McHardy: deepG: Deep Learning for Genome Sequence Data. R package version 0.3.1 .
#126262	A. Lissin, I. Schober, J. F. Witte, H. Lüken, A. Podstawka, J. Koblitz, B. Bunk, P. Dawyndt, P. Vandamme, P. de Vos, J. Overmann, L. C. Reimer: StrainInfo—the central database for linked microbial strain identifiers. ( DOI 10.1093/database/baaf059 )

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Lacticaseibacillus casei (CCUG 21451, IAM 12473, LMG 6904)

Name and taxonomic classification

Morphology

Cell morphology

Culture and growth conditions

Culture medium

Culture temp

Physiology and metabolism

Oxygen tolerance

Spore formation

Compound production

Murein

Metabolite utilization

Metabolite tests

Enzymes

API coryne

API zym

API 50CHac

Isolation, sampling and environmental information

Isolation source categories

Isolation

Taxonmaps

Interaction and safety

Risk assessment

Sequence information

Genome sequences

Genome browser: GCA_000829055

16S sequences

GC content

Genome-based predictions

Predictions

Literature

Literature

References

BacDive

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