Limosilactobacillus vaginalis (DSM 5837, ATCC 49540, NCTC 12197)

Name: Limosilactobacillus vaginalis (DSM 5837, ATCC 49540, NCTC 12197)
Creator: BacDive
License: http://creativecommons.org/licenses/by/4.0/

BacDive ID 6558

Type strain

Strain Designation Lac 19

Culture col. no. DSM 5837 ATCC 49540 NCTC 12197 CCUG 31452 Lac 19 9 more

NCBI tax ID(s) 1633

Special Collections DSMZ CCUG JCM KCTC CIP

History <- T.M. Embley, Lac 19 NCTC 12197 <-- T. M. Embley Lac 19 <-- W. Bossart. CIP <- 1999, C. Phillips, AFISC, Highett, Australia: strain CSCC 5252 <- LMG <- 1992, ATCC <- NCTC

Links

Limosilactobacillus vaginalis Lac 19 is an anaerobe, Gram-positive, rod-shaped bacterium that was isolated from vaginal swab from patient with trichomoniasis.

Gram-positive rod-shaped anaerobe genome sequence 16S sequence Bacteria

Name and taxonomic classification

SI-ID 277603

LMG 12891,ATCC 49540,NCTC 12197,CCUG 31452,NCDO 2810,CIP 105932,JCM 9505,NCIMB 702810,NCFB2810,CECT 4089,CCRC 14735,KCTC 3515,KCTC 3551,KCTC 3699,BCRC 14735,DSM 5837

@ref 20215

Last LPSN update 2026-02-09 11:19:15

Domain Bacteria

Phylum Bacillota

Class Bacilli

Order Lactobacillales

Family Lactobacillaceae

Genus Limosilactobacillus

Species Limosilactobacillus vaginalis

Full scientific name Limosilactobacillus vaginalis (Embley et al. 1989) Zheng et al. 2020

Synonyms (1)

Lactobacillus vaginalis

BacDive ID	Other strains from **Limosilactobacillus vaginalis** (5)	Type strain
160305	L. vaginalis Cla-CZ-13, DSM 108982
165606	L. vaginalis JCM 7771
174283	L. vaginalis HO100, CRBIP24.5
174284	L. vaginalis CRBIP24.50
174285	L. vaginalis 61H, CRBIP24.6

Morphology

Cell morphology

@ref	Gram stain	Cell shape	Confidence
123782	positive	rod-shaped
125438			91
125438	positive		95.062

Culture and growth conditions

Culture medium

@ref	Name	Medium link	Composition
2334	MRS MEDIUM (DSMZ Medium 11)	Medium recipe at MediaDive	Name: MRS MEDIUM (DSMZ Medium 11) Composition: Glucose 20.0 g/l Casein peptone 10.0 g/l Meat extract 10.0 g/l Na-acetate 5.0 g/l Yeast extract 5.0 g/l (NH4)3 citrate 2.0 g/l K2HPO4 2.0 g/l Tween 80 1.0 g/l MgSO4 x 7 H2O 0.2 g/l MnSO4 x H2O 0.05 g/l Distilled water
38591	MEDIUM 40- for Lactobacillus and Leuconostoc		Distilled water make up to (1000.000 ml);Man Rogosa Sharp agar (68.000 g)
123782	CIP Medium 40	Medium recipe at CIP

Culture temp

@ref	Growth	Type	Temperature (°C)
2334	positive	growth	37
38591	positive	growth	37
50607	positive	growth	37
50607	positive	growth	37-42
67770	positive	growth	37
123782	positive	growth	30-45
123782	negative	growth	10
123782	negative	growth	15
123782	negative	growth	22

Physiology and metabolism

Oxygen tolerance

@ref	Oxygen tolerance	Confidence
50607	anaerobe
50607	microaerophile
123782	facultative anaerobe
125439	microaerophile	97

Spore formation

@ref	Spore formation	Confidence
125438		92.017

Murein

@ref	Murein short key	Type
2334	A21.04	A4ß L-Orn-D-Asp

Metabolite utilization

@ref	Chebi-ID	Metabolite	Utilization activity	Kind of utilization tested
68371	27613 ChEBI	amygdalin	-	builds acid from	from API 50CH acid
68371	18305 ChEBI	arbutin	-	builds acid from	from API 50CH acid
68371	17057 ChEBI	cellobiose	-	builds acid from	from API 50CH acid
68371	17108 ChEBI	D-arabinose	-	builds acid from	from API 50CH acid
68371	18333 ChEBI	D-arabitol	-	builds acid from	from API 50CH acid
68377	15824 ChEBI	D-fructose	+	builds acid from	from API NH
68371	15824 ChEBI	D-fructose	+	builds acid from	from API 50CH acid
68371	28847 ChEBI	D-fucose	-	builds acid from	from API 50CH acid
68371	12936 ChEBI	D-galactose	+	builds acid from	from API 50CH acid
68371	17634 ChEBI	D-glucose	+	builds acid from	from API 50CH acid
68377	17634 ChEBI	D-glucose	+	builds acid from	from API NH
68371	62318 ChEBI	D-lyxose	-	builds acid from	from API 50CH acid
68371	16899 ChEBI	D-mannitol	-	builds acid from	from API 50CH acid
68371	16988 ChEBI	D-ribose	-	builds acid from	from API 50CH acid
68371	17924 ChEBI	D-sorbitol	-	builds acid from	from API 50CH acid
68371	16443 ChEBI	D-tagatose	-	builds acid from	from API 50CH acid
68371	65327 ChEBI	D-xylose	-	builds acid from	from API 50CH acid
68371	17113 ChEBI	erythritol	-	builds acid from	from API 50CH acid
68371	16813 ChEBI	galactitol	-	builds acid from	from API 50CH acid
68371	28066 ChEBI	gentiobiose	-	builds acid from	from API 50CH acid
68371	24265 ChEBI	gluconate	-	builds acid from	from API 50CH acid
68371	17754 ChEBI	glycerol	-	builds acid from	from API 50CH acid
68371	28087 ChEBI	glycogen	-	builds acid from	from API 50CH acid
68371	15443 ChEBI	inulin	-	builds acid from	from API 50CH acid
68371	30849 ChEBI	L-arabinose	-	builds acid from	from API 50CH acid
68371	18403 ChEBI	L-arabitol	-	builds acid from	from API 50CH acid
68371	18287 ChEBI	L-fucose	-	builds acid from	from API 50CH acid
68371	62345 ChEBI	L-rhamnose	-	builds acid from	from API 50CH acid
68371	17266 ChEBI	L-sorbose	-	builds acid from	from API 50CH acid
68371	65328 ChEBI	L-xylose	-	builds acid from	from API 50CH acid
68371	17716 ChEBI	lactose	+	builds acid from	from API 50CH acid
68377	17306 ChEBI	maltose	+	builds acid from	from API NH
68371	17306 ChEBI	maltose	+	builds acid from	from API 50CH acid
68371	6731 ChEBI	melezitose	-	builds acid from	from API 50CH acid
68371	28053 ChEBI	melibiose	+	builds acid from	from API 50CH acid
68371	320061 ChEBI	methyl alpha-D-glucopyranoside	-	builds acid from	from API 50CH acid
68371	43943 ChEBI	methyl alpha-D-mannoside	-	builds acid from	from API 50CH acid
68371	74863 ChEBI	methyl beta-D-xylopyranoside	-	builds acid from	from API 50CH acid
68371	17268 ChEBI	myo-inositol	-	builds acid from	from API 50CH acid
68371	59640 ChEBI	N-acetylglucosamine	-	builds acid from	from API 50CH acid
123782	17632 ChEBI	nitrate	-	reduction
123782	17632 ChEBI	nitrate	+	respiration
123782	16301 ChEBI	nitrite	-	reduction
68377	18257 ChEBI	ornithine	-	degradation	from API NH
68371		Potassium 2-ketogluconate	-	builds acid from	from API 50CH acid
68371		Potassium 5-ketogluconate	-	builds acid from	from API 50CH acid
68371	16634 ChEBI	raffinose	+	builds acid from	from API 50CH acid
68371	15963 ChEBI	ribitol	-	builds acid from	from API 50CH acid
68371	17814 ChEBI	salicin	-	builds acid from	from API 50CH acid
68371	28017 ChEBI	starch	-	builds acid from	from API 50CH acid
68377	17992 ChEBI	sucrose	-	builds acid from	from API NH
68371	17992 ChEBI	sucrose	+	builds acid from	from API 50CH acid
68371	27082 ChEBI	trehalose	-	builds acid from	from API 50CH acid
68377	27897 ChEBI	tryptophan	-	energy source	from API NH
68371	32528 ChEBI	turanose	-	builds acid from	from API 50CH acid
68377	16199 ChEBI	urea	-	hydrolysis	from API NH
68371	17151 ChEBI	xylitol	-	builds acid from	from API 50CH acid

Metabolite production

@ref	Chebi-ID	Metabolite	Production
68377	35581 ChEBI	indole		from API NH

Metabolite tests

@ref	Chebi-ID	Metabolite	Indole test	Voges-proskauer-test
123782	15688 ChEBI	acetoin		-
68377	35581 ChEBI	indole	-		from API NH

Enzymes

@ref	Value	Activity	Ec
68382	acid phosphatase	+	3.1.3.2	from API zym
123782	alcohol dehydrogenase	+	1.1.1.1
68377	alkaline phosphatase	-	3.1.3.1	from API NH
68382	alkaline phosphatase	-	3.1.3.1	from API zym
68382	alpha-chymotrypsin	-	3.4.21.1	from API zym
68382	alpha-fucosidase	-	3.2.1.51	from API zym
68382	alpha-galactosidase	+	3.2.1.22	from API zym
68382	alpha-glucosidase	-	3.2.1.20	from API zym
68382	alpha-mannosidase	-	3.2.1.24	from API zym
68382	beta-galactosidase	+	3.2.1.23	from API zym
68377	beta-galactosidase	-	3.2.1.23	from API NH
68382	beta-glucosidase	-	3.2.1.21	from API zym
68382	beta-glucuronidase	-	3.2.1.31	from API zym
68377	beta-lactamase	-	3.5.2.6	from API NH
123782	catalase	-	1.11.1.6
68382	cystine arylamidase	-	3.4.11.3	from API zym
68382	esterase (C 4)	+		from API zym
68382	esterase lipase (C 8)	+		from API zym
68377	gamma-glutamyltransferase	-	2.3.2.2	from API NH
68382	leucine arylamidase	+	3.4.11.1	from API zym
68377	lipase	+		from API NH
68382	lipase (C 14)	-		from API zym
123782	lysine decarboxylase	-	4.1.1.18
68382	N-acetyl-beta-glucosaminidase	-	3.2.1.52	from API zym
68382	naphthol-AS-BI-phosphohydrolase	+		from API zym
123782	ornithine decarboxylase	-	4.1.1.17
68377	ornithine decarboxylase	-	4.1.1.17	from API NH
123782	oxidase	-
68377	proline-arylamidase	-	3.4.11.5	from API NH
68382	trypsin	-	3.4.21.4	from API zym
68377	tryptophan deaminase	-	4.1.99.1	from API NH
68377	urease	-	3.5.1.5	from API NH
68382	valine arylamidase	-		from API zym

Fatty acid profile

Metadata FA analysis

@ref

50607

Fatty acid	Percentage	ECL
C18:1 ω9c	33.3	17.769
C16:0	23.7	16
C19:0 CYCLO ω9c	15.7	18.87
C18:1 ω7c /12t/9t	15.5	17.824
C14:0	7.4	14
C16:1 ω7c	4.4	15.819

API zym

@ref	Control	Alkaline phosphatase	Esterase (C 4)	2-naphtyl caprylateEsterase Lipase (C 8)	Lipase (C 14)	L-leucyl-2-naphthylamideLeucine arylamidase	L-valyl-2-naphthylamideValine arylamidase	L-cystyl-2-naphthylamideCystine arylamidase	Trypsin	alpha- Chymotrypsin	Acid phosphatase	Naphthol-AS-BI-phosphateNaphthol-AS-BI-phosphohydrolase	alpha- Galactosidase	beta- Galactosidase	beta- Glucuronidase	alpha- Glucosidase	beta- Glucosidase	N-acetyl-beta- glucosaminidase	alpha- Mannosidase	alpha- Fucosidase
123782	-	-	+	+	-	+	-	-	-	-	+	+	+	+	-	-	-	-	-	-

API 50CHac

@ref	ControlQ	GLY	ERY	DARA	LARA	RIB	DXYL	LXYL	ADO	MDX	GAL	GLU	FRU	MNE	SBE	RHA	DUL	INO	MAN	SOR	MDM	MDG	NAG	AMY	ARB	ESC	SAL	CEL	MAL	LAC	MEL	SAC	TRE	INU	MLZ	RAF	AMD	GLYG	XLT	GEN	TUR	LYX	TAG	DFUC	LFUC	DARL	LARL	GNT	2KG	5KG
2334	-	-	-	-	-	-	-	-	-	-	+	+	+	+	-	-	-	-	-	-	-	-	-	-	-	-	-	-	+	+	+	+	-	-	-	+	-	-	-	-	-	-	-	-	-	-	-	-	-	-
2334	-	-	-	-	-	-	-	-	-	-	+	+	+	-	-	-	-	-	-	-	-	-	-	-	-	+	-	-	+	+	+	+	-	-	-	+	-	-	-	-	-	-	-	-	-	-	-	-	-	-
2334	-	-	-	-	-	-	-	-	-	-	+	+	+	+	-	-	-	-	-	-	-	-	-	-	-	-	-	-	+	+	+	+	-	-	-	+	-	-	-	-	-	-	-	-	-	-	-	-	-	-

API NH

@ref	PEN	GLU	FRU	MAL	SAC	ODC	URE	LIP	PAL	beta GAL	ProA	GGT	IND
50607	-	+	+	+	-	-	-	+	-	-	-	-	-

Isolation, sampling and environmental information

Isolation source categories

Cat1	Cat2	Cat3
#Infection	#Disease	-
#Infection	#Patient	-
#Infection	#Patient	#Swab
#Host Body-Site	#Urogenital tract	#Vagina

Isolation

@ref	Sample type
2334	vaginal swab from patient with trichomoniasis
50607	Human vagina,patient with trichomoniasis
67770	Vagina of patients suffering from trichomonaiasis
123782	Human, Vagina

Taxonmaps

69479

Global distribution of 16S sequence LC096217 (>99% sequence identity) for Limosilactobacillus from Microbeatlas

Aquatic Samples	719
Soil Samples	1438
Animal Samples	55246
Plant Samples	398
Total Samples	57801

Interaction and safety

Risk assessment

@ref	Biosafety level	Biosafety level comment
2334	1	Risk group (German classification) According to TRBA 466
123782	1	Risk group (French classification) According to TRBA 466

Sequence information

Genome sequences

@ref	Description	Assembly level	INSDC accession	BV-BRC accession	IMG accession	NCBI tax ID	Score
66792	SRR9217392-mag-bin.4 assembly for Limosilactobacillus vaginalis DSM 5837 = ATCC 49540	contig	GCA_905371805	1423814.24		1423814	66.18
67770	ASM143591v1 assembly for Limosilactobacillus vaginalis DSM 5837 = ATCC 49540	scaffold	GCA_001435915	1423814.6	2667527865	1423814	49.44
67770	ASM15943v1 assembly for Limosilactobacillus vaginalis DSM 5837 = ATCC 49540	scaffold	GCA_000159435	525366.3	643886050	1423814	38.63

16S sequences

@ref	Description	Accession	Length	NCBI tax ID
20218	Lactobacillus vaginalis strain ATCC49540 16S ribosomal RNA gene, partial sequence	AF243177	1541	1633
20218	Lactobacillus vaginalis strain DSM 5837 16S-23S ribosomal RNA intergenic spacer and 23S ribosomal RNA gene, partial sequence	EU161598	796	1633
20218	Lactobacillus vaginalis gene for 16S rRNA, partial sequence, strain: JCM 9505	AB289311	648	1633
20218	Lactobacillus vaginalis 16S ribosomal RNA, partial sequence; 16S/23S intergenic spacer region, complete sequence; and 23S ribosomal RNA partial sequence	AF182731	672	1633
20218	L.vaginalis 16S rRNA gene	X61136	1488	1633
67770	Lactobacillus vaginalis gene for 16S ribosomal RNA, partial sequence, strain: JCM 9505	LC096217	1513	1633
124043	Lactobacillus vaginalis strain ATCC49540 16S ribosomal RNA gene, partial sequence.	AF243141	1505	47770
124043	Lactobacillus vaginalis strain ATCC49540 16S ribosomal RNA gene, partial sequence.	AF243142	1521	1596
124043	Lactobacillus vaginalis strain ATCC49540 16S ribosomal RNA gene, partial sequence.	AF243143	1502	109790
124043	Lactobacillus vaginalis strain ATCC49540 16S ribosomal RNA gene, partial sequence.	AF243144	1521	1596
124043	Lactobacillus vaginalis strain ATCC49540 16S ribosomal RNA gene, partial sequence.	AF243145	1524	97478
124043	Lactobacillus vaginalis strain ATCC49540 16S ribosomal RNA gene, partial sequence.	AF243146	1517	47715
124043	Lactobacillus vaginalis strain ATCC49540 16S ribosomal RNA gene, partial sequence.	AF243147	1518	47714
124043	Lactobacillus vaginalis strain ATCC49540 16S ribosomal RNA gene, partial sequence.	AF243148	1524	97478
124043	Lactobacillus vaginalis strain ATCC49540 16S ribosomal RNA gene, partial sequence.	AF243149	1525	1613
124043	Lactobacillus vaginalis strain ATCC49540 16S ribosomal RNA gene, partial sequence.	AF243150	1508	47770
124043	Lactobacillus vaginalis strain ATCC49540 16S ribosomal RNA gene, partial sequence.	AF243151	1521	1596
124043	Lactobacillus vaginalis strain ATCC49540 16S ribosomal RNA gene, partial sequence.	AF243152	1509	47770
124043	Lactobacillus vaginalis strain ATCC49540 16S ribosomal RNA gene, partial sequence.	AF243153	1513	109790
124043	Lactobacillus vaginalis strain ATCC49540 16S ribosomal RNA gene, partial sequence.	AF243154	1523	1633
124043	Lactobacillus vaginalis strain ATCC49540 16S ribosomal RNA gene, partial sequence.	AF243155	1511	109790
124043	Lactobacillus vaginalis strain ATCC49540 16S ribosomal RNA gene, partial sequence.	AF243156	1509	1596
124043	Lactobacillus vaginalis strain ATCC49540 16S ribosomal RNA gene, partial sequence.	AF243157	1508	1596
124043	Lactobacillus vaginalis strain ATCC49540 16S ribosomal RNA gene, partial sequence.	AF243158	1510	47770
124043	Lactobacillus vaginalis strain ATCC49540 16S ribosomal RNA gene, partial sequence.	AF243159	1511	109790
124043	Lactobacillus vaginalis strain ATCC49540 16S ribosomal RNA gene, partial sequence.	AF243160	1509	120548
124043	Lactobacillus vaginalis strain ATCC49540 16S ribosomal RNA gene, partial sequence.	AF243161	1512	109790
124043	Lactobacillus vaginalis strain ATCC49540 16S ribosomal RNA gene, partial sequence.	AF243162	1512	109790
124043	Lactobacillus vaginalis strain ATCC49540 16S ribosomal RNA gene, partial sequence.	AF243163	1502	120549
124043	Lactobacillus vaginalis strain ATCC49540 16S ribosomal RNA gene, partial sequence.	AF243164	1511	120476
124043	Lactobacillus vaginalis strain ATCC49540 16S ribosomal RNA gene, partial sequence.	AF243165	1522	1596
124043	Lactobacillus vaginalis strain ATCC49540 16S ribosomal RNA gene, partial sequence.	AF243166	1525	1613
124043	Lactobacillus vaginalis strain ATCC49540 16S ribosomal RNA gene, partial sequence.	AF243167	1497	47770
124043	Lactobacillus vaginalis strain ATCC49540 16S ribosomal RNA gene, partial sequence.	AF243168	1513	47714
124043	Lactobacillus vaginalis strain ATCC49540 16S ribosomal RNA gene, partial sequence.	AF243169	1512	47770
124043	Lactobacillus vaginalis strain ATCC49540 16S ribosomal RNA gene, partial sequence.	AF243170	1508	47770
124043	Lactobacillus vaginalis strain ATCC49540 16S ribosomal RNA gene, partial sequence.	AF243171	1510	47770
124043	Lactobacillus vaginalis strain ATCC49540 16S ribosomal RNA gene, partial sequence.	AF243172	1509	47770
124043	Lactobacillus vaginalis strain ATCC49540 16S ribosomal RNA gene, partial sequence.	AF243173	1518	1596
124043	Lactobacillus vaginalis strain ATCC49540 16S ribosomal RNA gene, partial sequence.	AF243174	1509	47770
124043	Lactobacillus vaginalis strain ATCC49540 16S ribosomal RNA gene, partial sequence.	AF243175	1513	47770

GC content

@ref	GC-content (mol%)	Method
2334	39.0
67770	40.5	genome sequence analysis
67770	39	thermal denaturation, midpoint method (Tm)

Genome-based predictions

Predictions

Predictions from Deep Learning for Genome Sequence Data. R package version 0.3.1 based on: Limosilactobacillus vaginalis DSM 5837 = ATCC 49540
NCBI: GCA_000159435

@ref	Trait	Model	Prediction	Confidence in %	In training data
125439	spore_formation	BacteriaNetⓘ	no	83.80	no
125439	motility	BacteriaNetⓘ	no	69.00	no
125439	gram_stain	BacteriaNetⓘ	positive	66.80	no
125439	oxygen_tolerance	BacteriaNetⓘ	microaerophile	97.00	no

Predictions from bacterial phenotypic traits through improved machine learning using high-quality, curated datasets based on: Lactobacillus vaginalis ATCC 49540
PATRIC: 525366.3

@ref	Trait	Model	Prediction	Confidence in %	In training data
125438	gram-positive	gram-positiveⓘ	yes	95.06	no
125438	anaerobic	anaerobicⓘ	no	76.77	no
125438	spore-forming	spore-formingⓘ	no	92.02	no
125438	aerobic	aerobicⓘ	no	93.63	yes
125438	thermophilic	thermophileⓘ	no	96.88	no
125438	flagellated	motile2+ⓘ	no	91.00	no

Literature

Topic	Title	Authors	Journal	DOI	Year
	Limosilactobacillus vaginalis Exerts Bifidogenic Effects: A Novel Postbiotic Strategy for Infant Prebiotic Supplementation.	Giordani B, Parolin C, Abruzzo A, Foschi C, Marangoni A, Luppi B, Vitali B.	Nutrients	10.3390/nu15204433	2023
	Calcium modulates growth and biofilm formation of Lactobacillus acidophilus ATCC 4356 and Lactiplantibacillus plantarum ATCC 14917.	Huynh U, King J, Zastrow ML.	Sci Rep	10.1038/s41598-025-98577-w	2025
	Lacticaseibacillus rhamnosus CA15 (DSM 33960) as a Candidate Probiotic Strain for Human Health.	Pino A, Vaccalluzzo A, Caggia C, Balzaretti S, Vanella L, Sorrenti V, Ronkainen A, Satokari R, Randazzo CL.	Nutrients	10.3390/nu14224902	2022
Genetics	Characterization of the genome of the dairy Lactobacillus helveticus bacteriophage {Phi}AQ113.	Zago M, Scaltriti E, Rossetti L, Guffanti A, Armiento A, Fornasari ME, Grolli S, Carminati D, Brini E, Pavan P, Felsani A, D'Urzo A, Moles A, Claude JB, Grandori R, Ramoni R, Giraffa G.	Appl Environ Microbiol	10.1128/aem.00620-13	2013
	Isolation of Limosilactobacillus mucosae G01 with inhibitory effects on porcine epidemic diarrhea virus in vitro from Bama pig gastroenteritis.	Zhang B, Shen H, Gou H, Wuri N, Zhang C, Liu Z, He H, Nie J, Qu Y, Geri L, Zhang J.	Front Microbiol	10.3389/fmicb.2024.1360098	2024
	Functional and Safety Profile of Limosilactobacillus vaginalis and Development of Oral Fast-Disintegrating Tablets for Gut Microbiota Modulation.	Giordani B, Monti F, Corazza E, Gasperini S, Parolin C, Abruzzo A, Foschi C, Marangoni A, Lenzi M, Luppi B, Vitali B.	Pharmaceutics	10.3390/pharmaceutics17081011	2025
Phylogeny	Assessing the impact of broiler genotype on cecal and tracheal microbiome composition using full-length 16S rRNA sequencing.	Poudel S, Rahman FA, Granados EAF, Adhikari Y, Naeem M, Rochell SJ, Bourassa D.	Poult Sci	10.1016/j.psj.2025.106072	2025
	Alleviation of fluoride-induced colitis by tea polysaccharides: Insights into the role of Limosilactobacillus vaginalis and butyric acid.	Zhao C, Chen G, Huang Y, Zhang Y, Li S, Jiang Z, Peng H, Wang J, Li D, Hou R, Peng C, Wan X, Cai H.	J Hazard Mater	10.1016/j.jhazmat.2024.134858	2024
Phylogeny	Full-length 16S rRNA sequencing revealed an altered microbiome diversity and composition of the jejunum and cecum in chicken infected with Eimeria necatrix.	Xue N, Feng Q, Zhu Y, Cheng C, Wang F, Liu D, Su S, Xu J, Hu J, Tao J.	Vet Parasitol	10.1016/j.vetpar.2025.110458	2025
Genetics	Complete genomes of Limosilactobacillus portuensis and Limosilactobacillus vaginalis isolated from the urine of postmenopausal women.	Nguyen VH, Sharon BM, Shipman BM, Zimmern PE, De Nisco NJ.	Microbiol Resour Announc	10.1128/mra.00883-23	2024
	Insights into population adaptation and biodiversity of lactic acid bacteria in challenged date palm leaves silaging, using MALDI-TOF MS.	Jawaid MZ, Ashfaq MY, Al-Ghouti M, Zouari N.	Curr Res Microb Sci	10.1016/j.crmicr.2024.100235	2024
	Functional and Safety Profile of Limosilactobacillus vaginalis and Development of Oral Fast-Disintegrating Tablets for Gut Microbiota Modulation	Giordani B, Monti F, Corazza E, Gasperini S, Parolin C, Abruzzo A, Foschi C, Marangoni A, Lenzi M, Luppi B, Vitali B.	Pharmaceutics		2025
	Peculiarities of vaginal microbiota in perimenopausal and postmenopausal women with type 2 diabetes mellitus.	Qiu X, Zhang M, Zhang L, Chen H, Gao M, Li W, Yu Z, Hou Z.	Ann Clin Microbiol Antimicrob	10.1186/s12941-025-00828-1	2025
Genetics	Complete genome sequence and genomic characterization of the probiotic Limosilactobacillus reuteri PSC102.	Lee GY, Cho HY, Sayem SAJ, Kim SJ, Ali MS, Park SC.	Open Vet J	10.5455/ovj.2025.v15.i6.15	2025
Pathogenicity	Diarrhea accompanies intestinal inflammation and intestinal mucosal microbiota dysbiosis during fatigue combined with a high-fat diet.	Liu J, Qiao B, Cai Y, Tan Z, Deng N.	BMC Microbiol	10.1186/s12866-023-02896-9	2023
Genetics	Shotgun metagenomics of the vaginal microbiome in cervical shortening and preterm birth risk.	Lee KY, Shin SH, Park G, Kang SH, Kang HJ, Kim J, Lee JJ, Son GH, Hong JY.	Sci Rep	10.1038/s41598-025-23737-x	2025
	Comprehensive study on the impact of ginger extract on laying performance, egg quality, inflammatory responses, intestinal barrier function, and cecal microbiome and resistome in laying hens.	Tong Y, Wang Y, Zhang J, Guo Y, Yuan T, Chen H, Zhang H, Zhan K, Zhao L, Ma Q, Huang S.	Poult Sci	10.1016/j.psj.2025.105448	2025
	Vaginal Lactobacillus Impair Candida Dimorphic Switching and Biofilm Formation.	Parolin C, Croatti V, Giordani B, Vitali B.	Microorganisms	10.3390/microorganisms10102091	2022
	Prebiotic Activity of Vaginal Lactobacilli on Bifidobacteria: from Concept to Formulation.	Giordani B, Abruzzo A, Parolin C, Foschi C, Laghi L, Marangoni A, Luppi B, Vitali B.	Microbiol Spectr	10.1128/spectrum.02009-22	2023
	Impact of Dapivirine and Placebo Vaginal Rings on the Microbiota of Adolescent, Lactating, and Postmenopausal Females.	Austin MN, Meyn LA, Avolia HA, Petrina MA, Cosentino LA, Alphonse C, Chen BA, Bunge K, Noguchi L, Beigi R, Squires K, Hillier SL.	J Infect Dis	10.1093/infdis/jiab590	2022
Genetics	Deep culturing the fecal microbiota of healthy laying hens.	Feng Z, Lorenc N, O'Brien B, Sun G, Li Z, Jung D, Ronholm J.	Anim Microbiome	10.1186/s42523-025-00395-y	2025
	Semen Trigonellae alleviates LPS-induced depressive behavior via enhancing the abundance of Ligilactobacillus spp.	Chang W, Guo J, Yang Y, Zou L, Fu Y, Li M, Li L, Li C, Wang X, Zhao X, Wu C.	Food Sci Nutr	10.1002/fsn3.4475	2024
	Probiotic and Metabolic Characterization of Vaginal Lactobacilli for a Potential Use in Functional Foods.	D'Alessandro M, Parolin C, Bukvicki D, Siroli L, Vitali B, De Angelis M, Lanciotti R, Patrignani F.	Microorganisms	10.3390/microorganisms9040833	2021
	Detoxification of Grape Pomace Contaminated with Ochratoxin A by Thermal-Pressure Treatment in Combination with Lactic Acid Bacteria Fermentation.	Aning-Dei E, Yu J, Ibrahim SA.	Microorganisms	10.3390/microorganisms13091972	2025
	Inhibitory effects of vaginal Lactobacilli on Candida albicans growth, hyphal formation, biofilm development, and epithelial cell adhesion.	Takano T, Kudo H, Eguchi S, Matsumoto A, Oka K, Yamasaki Y, Takahashi M, Koshikawa T, Takemura H, Yamagishi Y, Mikamo H, Kunishima H.	Front Cell Infect Microbiol	10.3389/fcimb.2023.1113401	2023
Genetics	New connections of medication use and polypharmacy with the gut microbiota composition and functional potential in a large population.	Larsson A, Ericson U, Jonsson D, Miari M, Athanasiadis P, Baldanzi G, Brunkwall L, Hellstrand S, Klinge B, Melander O, Nilsson PM, Fall T, Maziarz M, Orho-Melander M.	Sci Rep	10.1038/s41598-024-71571-4	2024
	Metagenomic insight into the vaginal microbiome in women infected with HPV 16 and 18.	Jung DR, Choi Y, Jeong M, Singh V, Jeon SY, Seo I, Park NJ, Lee YH, Park JY, Han HS, Shin JH, Chong GO.	NPJ Biofilms Microbiomes	10.1038/s41522-025-00747-1	2025
	Host-independent synergism between Lactobacillus crispatus and other vaginal lactobacilli.	Vander Donck L, Victor M, Van Beeck W, Van Rillaer T, Dillen J, Ahannach S, Wittouck S, Allonsius CN, Lebeer S.	Cell Rep	10.1016/j.celrep.2025.116171	2025
	Identification and Characterization of a Novel d-Branched-Chain Amino Acids Importer from Lactobacillus fermentum.	Aoki K, Mutaguchi Y, Hemmi H, Yoshimura T, Ito T.	Chembiochem	10.1002/cbic.202401075	2025
Genetics	Genomic and transcriptomic insights into vertebrate host-specific Lactobacillus johnsonii adaptation in the gastrointestinal tract.	Ravi K, Falkowski NR, Huffnagle GB.	mSphere	10.1128/msphere.00052-25	2025
Genetics	Diet-induced changes in the jejunal microbiota of developing broilers reduce the abundance of Enterococcus hirae and Enterococcus faecium.	Stege PB, Schokker D, Harders F, Kar SK, Stockhofe N, Perricone V, Rebel JMJ, de Jong IC, Bossers A.	BMC Genomics	10.1186/s12864-024-10496-8	2024
Genetics	Genomic diversity of genus Limosilactobacillus.	Ksiezarek M, Grosso F, Ribeiro TG, Peixe L.	Microb Genom	10.1099/mgen.0.000847	2022
	Gut microbiota and sleep: Interaction mechanisms and therapeutic prospects.	Lin Z, Jiang T, Chen M, Ji X, Wang Y.	Open Life Sci	10.1515/biol-2022-0910	2024
	Antimicrobial activity of Limosilactobacillus fermentum strains isolated from the human oral cavity against Streptococcus mutans.	Park DY, Hwang J, Kim Y, Lee D, Kim YY, Kim HS, Hwang I.	Sci Rep	10.1038/s41598-023-35168-7	2023
	Florfenicol-induced dysbiosis impairs intestinal homeostasis and host immune system in laying hens.	Yu K, Choi I, Kim M, Pyung YJ, Lee JS, Choi Y, Won S, Kim Y, Park BC, Han SH, Park TS, Dalgaard TS, Yun CH.	J Anim Sci Biotechnol	10.1186/s40104-025-01186-w	2025
Genetics	Resveratrol Improves Hyperuricemia and Ameliorates Renal Injury by Modulating the Gut Microbiota.	Zhou Y, Zeng Y, Wang R, Pang J, Wang X, Pan Z, Jin Y, Chen Y, Yang Y, Ling W.	Nutrients	10.3390/nu16071086	2024
	Exopolysaccharides from vaginal lactobacilli modulate microbial biofilms.	Giordani B, Naldi M, Croatti V, Parolin C, Erdogan U, Bartolini M, Vitali B.	Microb Cell Fact	10.1186/s12934-023-02053-x	2023
	Characterizing the chicken gut colonization ability of a diverse group of bacteria.	Poudel B, Shterzer N, Sbehat Y, Ben-Porat N, Rakover M, Tovy-Sharon R, Wolicki D, Rahamim S, Bar-Shira E, Mills E.	Poult Sci	10.1016/j.psj.2022.102136	2022
	Gut microbiome compositional and functional features associate with Alzheimer's disease pathology.	Kang JW, Khatib LA, Heston MB, Dilmore AH, Labus JS, Deming Y, Schimmel L, Blach C, McDonald D, Gonzalez A, Bryant M, Ulland TK, Johnson SC, Asthana S, Carlsson CM, Chin NA, Blennow K, Zetterberg H, Rey FE, Alzheimer Gut Microbiome Project Consortium, Kaddurah-Daouk R, Knight R, Bendlin BB.	Alzheimers Dement	10.1002/alz.70417	2025
	Cross-Cohort Gut Microbiome Signatures of Irritable Bowel Syndrome Presentation and Treatment.	Li J, Li J, Ghosh TS, Arendt E, Shanahan F, O'Toole PW.	Adv Sci (Weinh)	10.1002/advs.202308313	2024
	Comparative genomics of Lentilactobacillus buchneri reveals strain-level hyperdiversity and broad-spectrum CRISPR immunity against human and livestock gut phages.	Gumustop I, Genel I, Kurt IC, Ortakci F.	PLoS One	10.1371/journal.pone.0325832	2025
	A quinolone N-oxide antibiotic selectively targets Neisseria gonorrhoeae via its toxin-antitoxin system.	Mix AK, Nguyen THN, Schuhmacher T, Szamosvari D, Muenzner P, Haas P, Heeb L, Wami HT, Dobrindt U, Delikkafa YO, Mayer TU, Bottcher T, Hauck CR.	Nat Microbiol	10.1038/s41564-025-01968-y	2025
	Modeling the weaning diet of piglets with fermented feed material: effects on growth performance and health parameters.	Badaras S, Starkute V, Mockus E, Ruzauskas M, Klupsaite D, Mozuriene E, Dailidaviciene J, Dauksiene A, Vadopalas L, Metzler-Zebeli BU, Bartkiene E.	Front Vet Sci	10.3389/fvets.2025.1616209	2025
	Oral Lactobacillus species and their probiotic capabilities in patients with periodontitis and periodontally healthy individuals.	Etebarian A, Sheshpari T, Kabir K, Sadeghi H, Moradi A, Hafedi A.	Clin Exp Dent Res	10.1002/cre2.740	2023
	The Effect of Human Milk Oligosaccharides and Bifidobacterium longum subspecies infantis Bi-26 on Simulated Infant Gut Microbiome and Metabolites.	Salli K, Hirvonen J, Anglenius H, Hibberd AA, Ahonen I, Saarinen MT, Maukonen J, Ouwehand AC.	Microorganisms	10.3390/microorganisms11061553	2023
	Lactobacillus salivarius CML352 Isolated from Chinese Local Breed Chicken Modulates the Gut Microbiota and Improves Intestinal Health and Egg Quality in Late-Phase Laying Hens.	Xu C, Wei F, Yang X, Feng Y, Liu D, Hu Y.	Microorganisms	10.3390/microorganisms10040726	2022
	Microbiota dynamics, metabolic and immune interactions in the cervicovaginal environment and their role in spontaneous preterm birth.	Onyango S, Mi JD, Koech A, Okiro P, Temmerman M, von Dadelszen P, Tribe RM, Omuse G, PRECISE Network.	Front Immunol	10.3389/fimmu.2023.1306473	2023
	In Silico Characterisation of Putative Prophages in Lactobacillaceae Used in Probiotics for Vaginal Health.	Happel AU, Kullin BR, Gamieldien H, Jaspan HB, Varsani A, Martin D, Passmore JS, Froissart R.	Microorganisms	10.3390/microorganisms10020214	2022
Pathogenicity	Evidence of host specificity in Lactobacillus johnsonii genomes and its influence on probiotic potential in poultry.	Johnson A, Miller EA, Weber B, Figueroa CF, Aguayo JM, Johny AK, Noll S, Brannon J, Kozlowicz B, Johnson TJ.	Poult Sci	10.1016/j.psj.2023.102858	2023
Metabolism	Inhibition of intestinal FXR activity as a possible mechanism for the beneficial effects of a probiotic mix supplementation on lipid metabolism alterations and weight gain in mice fed a high fat diet.	Beau A, Benoit B, Le Barz M, Meugnier E, Penhoat A, Calzada C, Pinteur C, Loizon E, Chanon S, Vieille-Marchiset A, Sauvinet V, Godet M, Laugerette F, Holowacz S, Jacouton E, Michalski MC, Vidal H.	Gut Microbes	10.1080/19490976.2023.2281015	2023
	Conjugative DNA Transfer From E. coli to Transformation-Resistant Lactobacilli.	Samperio S, Guzman-Herrador DL, May-Cuz R, Martin MC, Alvarez MA, Llosa M.	Front Microbiol	10.3389/fmicb.2021.606629	2021
	Long-term stability of the urogenital microbiota of asymptomatic European women.	Ksiezarek M, Ugarcina-Perovic S, Rocha J, Grosso F, Peixe L.	BMC Microbiol	10.1186/s12866-021-02123-3	2021
	Fecal microbiota profiles of growing pigs and their relation to growth performance.	Konig E, Beasley S, Heponiemi P, Kivinen S, Rakkolainen J, Salminen S, Collado MC, Borman T, Lahti L, Piirainen V, Valros A, Heinonen M.	PLoS One	10.1371/journal.pone.0302724	2024
Phylogeny	Analysis of the Microbial Intestinal Tract in Broiler Chickens during the Rearing Period.	Stamilla A, Ruiz-Ruiz S, Artacho A, Pons J, Messina A, Lucia Randazzo C, Caggia C, Lanza M, Moya A.	Biology (Basel)	10.3390/biology10090942	2021
	A citizen-science-enabled catalogue of the vaginal microbiome and associated factors.	Lebeer S, Ahannach S, Gehrmann T, Wittouck S, Eilers T, Oerlemans E, Condori S, Dillen J, Spacova I, Vander Donck L, Masquillier C, Allonsius CN, Bron PA, Van Beeck W, De Backer C, Donders G, Verhoeven V.	Nat Microbiol	10.1038/s41564-023-01500-0	2023
	Herd-Level and Individual Differences in Fecal Lactobacilli Dynamics of Growing Pigs.	Konig E, Sali V, Heponiemi P, Salminen S, Valros A, Junnikkala S, Heinonen M.	Animals (Basel)	10.3390/ani11010113	2021
	Acids produced by lactobacilli inhibit the growth of commensal Lachnospiraceae and S24-7 bacteria.	Brownlie EJE, Chaharlangi D, Wong EO, Kim D, Navarre WW.	Gut Microbes	10.1080/19490976.2022.2046452	2022
Metabolism	Co-Occurrence of Regulated and Emerging Mycotoxins in Corn Silage: Relationships with Fermentation Quality and Bacterial Communities.	Gallo A, Ghilardelli F, Atzori AS, Zara S, Novak B, Faas J, Fancello F.	Toxins (Basel)	10.3390/toxins13030232	2021
	Application of Ligilactobacillus salivarius CECT5713 to Achieve Term Pregnancies in Women with Repetitive Abortion or Infertility of Unknown Origin by Microbiological and Immunological Modulation of the Vaginal Ecosystem.	Fernandez L, Castro I, Arroyo R, Alba C, Beltran D, Rodriguez JM.	Nutrients	10.3390/nu13010162	2021
Phylogeny	The genome of the Lactobacillus sanfranciscensis temperate phage EV3.	Ehrmann MA, Angelov A, Picozzi C, Foschino R, Vogel RF	BMC Res Notes	10.1186/1756-0500-6-514	2013
Phylogeny	Limosilactobacillus urinaemulieris sp. nov. and Limosilactobacillus portuensis sp. nov. isolated from urine of healthy women.	Ksiezarek M, Ribeiro TG, Rocha J, Grosso F, Perovic SU, Peixe L	Int J Syst Evol Microbiol	10.1099/ijsem.0.004726	2021

References

#2334	Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 5837
#20215	Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 )
#20218	Verslyppe, B., De Smet, W., De Baets, B., De Vos, P., Dawyndt P.: StrainInfo introduces electronic passports for microorganisms.. Syst Appl Microbiol. 37: 42 - 50 2014 ( DOI 10.1016/j.syapm.2013.11.002 , PubMed 24321274 )
#38591	; Curators of the CIP;
#50607	Culture Collection University of Gothenburg (CCUG) ; Curators of the CCUG; CCUG 31452
#66792	Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) .
#67770	Japan Collection of Microorganism (JCM) ; Curators of the JCM;
#68371	Automatically annotated from API 50CH acid .
#68377	Automatically annotated from API NH .
#68382	Automatically annotated from API zym .
#69479	João F Matias Rodrigues, Janko Tackmann,Gregor Rot, Thomas SB Schmidt, Lukas Malfertheiner, Mihai Danaila,Marija Dmitrijeva, Daniela Gaio, Nicolas Näpflin and Christian von Mering. University of Zurich.: MicrobeAtlas 1.0 beta .
#123782	Collection of Institut Pasteur ; Curators of the CIP; CIP 105932
#124043	Isabel Schober, Julia Koblitz: Data extracted from sequence databases, automatically matched based on designation and taxonomy .
#125438	Julia Koblitz, Lorenz Christian Reimer, Rüdiger Pukall, Jörg Overmann: Predicting bacterial phenotypic traits through improved machine learning using high-quality, curated datasets. 2024 ( DOI 10.1101/2024.08.12.607695 )
#125439	Philipp Münch, René Mreches, Martin Binder, Hüseyin Anil Gündüz, Xiao-Yin To, Alice McHardy: deepG: Deep Learning for Genome Sequence Data. R package version 0.3.1 .
#126262	A. Lissin, I. Schober, J. F. Witte, H. Lüken, A. Podstawka, J. Koblitz, B. Bunk, P. Dawyndt, P. Vandamme, P. de Vos, J. Overmann, L. C. Reimer: StrainInfo—the central database for linked microbial strain identifiers. ( DOI 10.1093/database/baaf059 )

Rate our new design

Content

About us

Limosilactobacillus vaginalis (DSM 5837, ATCC 49540, NCTC 12197)

Name and taxonomic classification

Morphology

Cell morphology

Culture and growth conditions

Culture medium

Culture temp

Physiology and metabolism

Oxygen tolerance

Spore formation

Murein

Metabolite utilization

Metabolite production

Metabolite tests

Enzymes

Fatty acid profile?

API zym

API 50CHac

API NH

Isolation, sampling and environmental information

Isolation source categories

Isolation

Taxonmaps

Interaction and safety

Risk assessment

Sequence information

Genome sequences

Genome browser: GCA_905371805

16S sequences

GC content

Genome-based predictions

Predictions

Literature

Literature

References

BacDive

Help

Social Media

Fatty acid profile