Lacticaseibacillus paracasei subsp. paracasei (DSM 5622, ATCC 25302, NCDO 151)

Name: Lacticaseibacillus paracasei subsp. paracasei (DSM 5622, ATCC 25302, NCDO 151)
Creator: BacDive
License: http://creativecommons.org/licenses/by/4.0/

BacDive ID 6548

Type strain

Strain Designation RO94

Culture col. no. DSM 5622 ATCC 25302 NCDO 151 CCUG 32212 LMG 13087 11 more

NCBI tax ID(s) 525337 1597 47714

Special Collections DSMZ CCUG JCM KCTC CIP

History <- NCDO <- NIRD, RO94 (Lactobacillus casei) NCFB 151 <-- NIRD. CIP <- 1993, F. Gasser, Inst. Pasteur, Paris, France <- NCDO, Lactobacillus casei

Links

Lacticaseibacillus paracasei subsp. paracasei RO94 is an anaerobe, Gram-positive, rod-shaped bacterium that was isolated from Milk products.

Gram-positive rod-shaped anaerobe genome sequence 16S sequence Bacteria

Name and taxonomic classification

SI-ID 7366

LMG 13087,ATCC 25302,DSM 5622,NCFB 151,NBIMCC 8458,NCDO 151,CCUG 32212,JCM 8130,CIP 103918,CCRC 12248,CECT 4022,IFO 15889,NCIMB 700151,CCM 1753,CCUG 31212,KCTC 3510,NBRC 15889,BCRC 12248

@ref 20215

Last LPSN update 2026-02-09 11:19:15

Domain Bacteria

Phylum Bacillota

Class Bacilli

Order Lactobacillales

Family Lactobacillaceae

Genus Lacticaseibacillus

Species Lacticaseibacillus paracasei subsp. paracasei

Full scientific name Lacticaseibacillus paracasei subsp. paracasei (Collins et al. 1989) Zheng et al. 2020

Synonyms (1)

Lactobacillus paracasei subsp. paracasei

BacDive ID	Other strains from **Lacticaseibacillus paracasei subsp. paracasei** (19)	Type strain
6545	L. paracasei subsp. paracasei No. 59, DSM 2649
6546	L. paracasei subsp. paracasei DSM 4905, ATCC 11578
6549	L. paracasei subsp. paracasei A22/73, DSM 8741, NCFB 2976
6550	L. paracasei subsp. paracasei A112/73, DSM 8742, NCFB 2977
6551	L. paracasei subsp. paracasei 85 E, DSM 20006, JCM 1163, KCTC 3166
6552	L. paracasei subsp. paracasei 40, DSM 20008, ATCC 25598, NCDO 2743, NCIB ...
6553	L. paracasei subsp. paracasei C 17, CCUG 34680, DSM 20020, ATCC 27216, ...
6554	L. paracasei subsp. paracasei 41, DSM 20207, NCDO 1977, JCM 1161
6555	L. paracasei subsp. paracasei S, DSM 20312, ATCC 27092
6556	L. paracasei subsp. paracasei 28, DSM 20244
6557	L. paracasei subsp. paracasei 9664, A 13, BU 240, Ep 300, Epsilon, PBR ...
6659	L. paracasei subsp. paracasei B41, DSM 23505
160021	L. paracasei subsp. paracasei GCRL 163, DSM 111790
160981	L. paracasei subsp. paracasei JCM 1053, IAM 1043
161128	L. paracasei subsp. paracasei JCM 1109
161129	L. paracasei subsp. paracasei JCM 1111
163406	L. paracasei subsp. paracasei JCM 2769
165742	L. paracasei subsp. paracasei JCM 8131, NCFB 205, NCIMB 2378, NCTC 2378
165743	L. paracasei subsp. paracasei JCM 8133, NCDO 1202

Morphology

Cell morphology

@ref	Gram stain	Cell shape	Confidence
121547	positive	rod-shaped
125438			92
125438	positive		91.81

Culture and growth conditions

Culture medium

@ref	Name	Medium link	Composition
2263	MRS MEDIUM (DSMZ Medium 11)	Medium recipe at MediaDive	Name: MRS MEDIUM (DSMZ Medium 11) Composition: Glucose 20.0 g/l Casein peptone 10.0 g/l Meat extract 10.0 g/l Na-acetate 5.0 g/l Yeast extract 5.0 g/l (NH4)3 citrate 2.0 g/l K2HPO4 2.0 g/l Tween 80 1.0 g/l MgSO4 x 7 H2O 0.2 g/l MnSO4 x H2O 0.05 g/l Distilled water
34920	MEDIUM 40- for Lactobacillus and Leuconostoc		Distilled water make up to (1000.000 ml);Man Rogosa Sharp agar (68.000 g)
121547	CIP Medium 40	Medium recipe at CIP

Culture temp

@ref	Growth	Type	Temperature (°C)
2263	positive	growth	30
34920	positive	growth	30
50901	positive	growth	30
50901	positive	growth	37
67770	positive	growth	30
121547	positive	growth	15-37
121547	negative	growth	45

Physiology and metabolism

Oxygen tolerance

@ref	Oxygen tolerance	Confidence
50901	anaerobe
50901	microaerophile
121547	facultative anaerobe
125439	obligate aerobe	94.5

Murein

@ref	Murein short key	Type
2263	A11.31	A4alpha L-Lys-D-Asp

Metabolite utilization

@ref	Chebi-ID	Metabolite	Utilization activity	Kind of utilization tested
68371	27613 ChEBI	amygdalin	-	builds acid from	from API 50CH acid
68371	18305 ChEBI	arbutin	+	builds acid from	from API 50CH acid
68371	17057 ChEBI	cellobiose	+	builds acid from	from API 50CH acid
68371	17108 ChEBI	D-arabinose	-	builds acid from	from API 50CH acid
68371	18333 ChEBI	D-arabitol	-	builds acid from	from API 50CH acid
68371	15824 ChEBI	D-fructose	+	builds acid from	from API 50CH acid
68371	28847 ChEBI	D-fucose	-	builds acid from	from API 50CH acid
68371	12936 ChEBI	D-galactose	+	builds acid from	from API 50CH acid
68371	17634 ChEBI	D-glucose	+	builds acid from	from API 50CH acid
68371	62318 ChEBI	D-lyxose	-	builds acid from	from API 50CH acid
68371	16899 ChEBI	D-mannitol	+	builds acid from	from API 50CH acid
68371	16024 ChEBI	D-mannose	+	builds acid from	from API 50CH acid
68371	16988 ChEBI	D-ribose	+	builds acid from	from API 50CH acid
68371	17924 ChEBI	D-sorbitol	-	builds acid from	from API 50CH acid
68371	65327 ChEBI	D-xylose	-	builds acid from	from API 50CH acid
68371	17113 ChEBI	erythritol	-	builds acid from	from API 50CH acid
68371	4853 ChEBI	esculin	+	builds acid from	from API 50CH acid
68371	16813 ChEBI	galactitol	-	builds acid from	from API 50CH acid
68371	17754 ChEBI	glycerol	-	builds acid from	from API 50CH acid
68371	28087 ChEBI	glycogen	-	builds acid from	from API 50CH acid
68371	15443 ChEBI	inulin	-	builds acid from	from API 50CH acid
68371	30849 ChEBI	L-arabinose	-	builds acid from	from API 50CH acid
68371	18403 ChEBI	L-arabitol	-	builds acid from	from API 50CH acid
68371	18287 ChEBI	L-fucose	-	builds acid from	from API 50CH acid
68371	62345 ChEBI	L-rhamnose	-	builds acid from	from API 50CH acid
68371	17266 ChEBI	L-sorbose	-	builds acid from	from API 50CH acid
68371	65328 ChEBI	L-xylose	-	builds acid from	from API 50CH acid
68371	28053 ChEBI	melibiose	-	builds acid from	from API 50CH acid
68371	320061 ChEBI	methyl alpha-D-glucopyranoside	-	builds acid from	from API 50CH acid
68371	43943 ChEBI	methyl alpha-D-mannoside	-	builds acid from	from API 50CH acid
68371	74863 ChEBI	methyl beta-D-xylopyranoside	-	builds acid from	from API 50CH acid
68371	17268 ChEBI	myo-inositol	-	builds acid from	from API 50CH acid
68371	59640 ChEBI	N-acetylglucosamine	+	builds acid from	from API 50CH acid
121547	17632 ChEBI	nitrate	-	reduction
121547	17632 ChEBI	nitrate	+	respiration
121547	16301 ChEBI	nitrite	-	reduction
68371		Potassium 2-ketogluconate	-	builds acid from	from API 50CH acid
68371		Potassium 5-ketogluconate	-	builds acid from	from API 50CH acid
68371	16634 ChEBI	raffinose	-	builds acid from	from API 50CH acid
68371	15963 ChEBI	ribitol	-	builds acid from	from API 50CH acid
68371	17814 ChEBI	salicin	+	builds acid from	from API 50CH acid
68371	28017 ChEBI	starch	-	builds acid from	from API 50CH acid
68371	17151 ChEBI	xylitol	-	builds acid from	from API 50CH acid

Antibiotic resistance

@ref	Metabolite	Is sensitive	Is resistant
121547	0129 (2,4-Diamino-6,7-di-iso-propylpteridine phosphate)

Enzymes

@ref	Value	Activity	Ec
68382	acid phosphatase	+	3.1.3.2	from API zym
121547	alcohol dehydrogenase	-	1.1.1.1
68382	alkaline phosphatase	+	3.1.3.1	from API zym
68382	alpha-chymotrypsin	-	3.4.21.1	from API zym
68382	alpha-fucosidase	-	3.2.1.51	from API zym
68382	alpha-galactosidase	-	3.2.1.22	from API zym
68382	alpha-glucosidase	+	3.2.1.20	from API zym
68382	alpha-mannosidase	-	3.2.1.24	from API zym
68382	beta-galactosidase	-	3.2.1.23	from API zym
68382	beta-glucosidase	+	3.2.1.21	from API zym
68382	beta-glucuronidase	-	3.2.1.31	from API zym
121547	catalase	-	1.11.1.6
68382	cystine arylamidase	+	3.4.11.3	from API zym
68382	esterase (C 4)	+		from API zym
68382	esterase lipase (C 8)	+		from API zym
68382	leucine arylamidase	+	3.4.11.1	from API zym
68382	lipase (C 14)	-		from API zym
121547	lysine decarboxylase	-	4.1.1.18
68382	N-acetyl-beta-glucosaminidase	-	3.2.1.52	from API zym
68382	naphthol-AS-BI-phosphohydrolase	+		from API zym
121547	ornithine decarboxylase	-	4.1.1.17
121547	oxidase	-
68382	trypsin	-	3.4.21.4	from API zym
68382	valine arylamidase	+		from API zym

API zym

@ref	Control	Alkaline phosphatase	Esterase (C 4)	2-naphtyl caprylateEsterase Lipase (C 8)	Lipase (C 14)	L-leucyl-2-naphthylamideLeucine arylamidase	L-valyl-2-naphthylamideValine arylamidase	L-cystyl-2-naphthylamideCystine arylamidase	Trypsin	alpha- Chymotrypsin	Acid phosphatase	Naphthol-AS-BI-phosphateNaphthol-AS-BI-phosphohydrolase	alpha- Galactosidase	beta- Galactosidase	beta- Glucuronidase	alpha- Glucosidase	beta- Glucosidase	N-acetyl-beta- glucosaminidase	alpha- Mannosidase	alpha- Fucosidase
121547	-	+	+	+	-	+	+	+	-	-	+	+	-	-	-	+	+	-	-	-

API 50CHac

@ref	ControlQ	GLY	ERY	DARA	LARA	RIB	DXYL	LXYL	ADO	MDX	GAL	GLU	FRU	MNE	SBE	RHA	DUL	INO	MAN	SOR	MDM	MDG	NAG	AMY	ARB	ESC	SAL	CEL	MAL	LAC	MEL	SAC	TRE	INU	MLZ	RAF	AMD	GLYG	XLT	GEN	TUR	LYX	TAG	DFUC	LFUC	DARL	LARL	GNT	2KG	5KG
2263	-	-	-	-	-	+	-	-	-	-	+	+	+	+	-	-	-	-	+	-	-	-	+	-	+	+	+	+	+	+	-	+	+	-	+	-	-	-	-	+	+	-	+	-	-	-	-	-	-	-
2263	-	-	-	-	-	+	-	-	-	-	+	+	+	+	-	-	-	-	+	-	-	-	+	-	+	+	+	+	-	+	-	-	+	-	+	-	-	-	-	-	+	-	+	-	-	-	-	-	-	-
2263	-	-	-	-	-	+	-	-	-	-	+	+	+	+	-	-	-	-	+	-	-	-	+	-	+	+	+	+	+	+	-	-	+	-	+	-	-	-	-	+	+	-	+	-	-	-	-	-	-	-
2263	-	-	-	-	-	+	-	-	-	-	+	+	+	+	-	-	-	-	+	-	-	-	+	-	+	+	+	+	-	+	-	-	+	-	+	-	-	-	-	-	+	-	+	-	-	-	-	-	-	-
2263	-	-	-	-	-	+	-	-	-	-	+	+	+	+	-	-	-	-	+	-	-	-	+	-	+	+	+	+	-	+	-	+	+	-	+	-	-	-	-	+	+	-	+	-	-	-	-	+	-	-
2263	-	-	-	-	-	+	-	-	-	-	+	+	+	+	-	-	-	-	+	-	-	-	+	-	+	+	+	+	+	+	-	+	+	-	+	-	-	-	-	+	+	-	+	-	-	-	-	+	-	-
2263	-	-	-	-	-	+	-	-	-	-	+	+	+	+	-	-	-	-	+	-	-	-	+	-	+	+	+	+	+	+	-	+	+	-	+	-	-	-	-	+	+	-	+	-	-	-	-	-	-	-
121547	not determinedn.d.	-	-	-	-	+	-	-	-	-	+	+	+	+	-	-	-	-	+	-	-	-	+	-	+	+	+	+	+	+/-	-	-	+/-	-	+/-	-	-	-	-	-	+/-	-	+/-	-	-	-	-	+/-	-	-

Isolation, sampling and environmental information

Isolation source categories

Cat1	Cat2	Cat3
#Engineered	#Food production	#Dairy product
#Host Body Product	#Fluids	#Milk

Isolation

@ref	Sample type
50901	Milk products
67770	Milk products

Taxonmaps

69479

Global distribution of 16S sequence LC096209 (>99% sequence identity) for Lactobacillaceae from Microbeatlas

Aquatic Samples	2397
Soil Samples	1801
Animal Samples	39363
Plant Samples	883
Total Samples	44444

Interaction and safety

Risk assessment

@ref	Pathogenicity human	Biosafety level	Biosafety level comment
2263	yes, in single cases	1	Risk group (German classification) According to TRBA 466
121547		1	Risk group (French classification) According to TRBA 466

Sequence information

Genome sequences

@ref	Description	Assembly level	INSDC accession	BV-BRC accession	IMG accession	NCBI tax ID	Score
66792	ASM82903v1 assembly for Lacticaseibacillus paracasei subsp. paracasei JCM 8130	complete	GCA_000829035	1226298.3	2912347755	47714	96.66
66792	ASM798912v1 assembly for Lacticaseibacillus paracasei subsp. paracasei NBRC 15889	contig	GCA_007989125	47714.17		47714	51.45
67770	ASM435465v1 assembly for Lacticaseibacillus paracasei subsp. paracasei ATCC 25302	scaffold	GCA_004354655	47714.15		47714	51.23
67770	ASM143638v1 assembly for Lacticaseibacillus paracasei subsp. paracasei ATCC 25302 = DSM 5622 = JCM 8130	contig	GCA_001436385	1423829.3	2667528038	525337	44.3
67770	ASM15949v1 assembly for Lacticaseibacillus paracasei subsp. paracasei ATCC 25302 = DSM 5622 = JCM 8130	scaffold	GCA_000159495	525337.3	643886051	525337	43.85

16S sequences

@ref	Description	Accession	Length	NCBI tax ID
20218	Lactobacillus paracasei strain ATCC 25302 16S ribosomal RNA gene, partial sequence	HQ423165	1441	1597
20218	Lactobacillus paracasei subsp. paracasei strain CECT 4022 16S ribosomal RNA gene, partial sequence	AY196966	525	47714
20218	Lactobacillus paracasei subsp. paracasei genes for 16S rRNA, 16S-23S internal transcribed spacer, tRNA-Ile, tRNA-Ala, 23S rRNA, partial and complete sequence, strain:JCM 8130	AB237506	572	47714
20218	Lactobacillus paracasei subsp. paracasei genes for 16S rRNA, 16S-23S internal transcribed spacer, 23S rRNA, partial sequence, strain:JCM 8130	AB237507	364	47714
20218	Lactobacillus paracasei subsp. paracasei gene for 16S rRNA, partial sequence, strain: JCM 8130	AB289225	670	47714
20218	Lactobacillus paracasei subsp. paracasei gene for 16S rRNA, partial sequence	D79212	1522	47714
20218	Lactobacillus paracasei subsp. paracasei gene for 16S rRNA, partial sequence, strain: NBRC 15889	AB626054	1495	47714
20218	Lacticaseibacillus paracasei subsp. paracasei gene for 16S rRNA, partial sequence, strain: YIT 0209 (= NCDO 151)	AB008205	1561	1582
67770	Lactobacillus paracasei subsp. paracasei gene for 16S ribosomal RNA, partial sequence, strain: JCM 8130	LC096209	1511	47714
124043	Lactobacillus paracasei strain NBRC 15889 16S ribosomal RNA gene, partial sequence.	MK852178	691	1597

GC content

@ref	GC-content (mol%)	Method
67770	46.5	genome sequence analysis

Genome-based predictions

Predictions

Predictions from Deep Learning for Genome Sequence Data. R package version 0.3.1 based on: Lactobacillus paracasei subsp. paracasei JCM 8130
PATRIC: 1226298.3

@ref	Trait	Model	Prediction	Confidence in %	In training data
125439	oxygen_tolerance	BacteriaNetⓘ	obligate aerobe	94.50	no
125439	gram_stain	BacteriaNetⓘ	positive	83.90	no
125439	motility	BacteriaNetⓘ	no	58.10	no
125439	spore_formation	BacteriaNetⓘ	no	85.00	no

Predictions from bacterial phenotypic traits through improved machine learning using high-quality, curated datasets based on: Lactobacillus paracasei subsp. paracasei JCM 8130
PATRIC: 1226298.3

@ref	Trait	Model	Prediction	Confidence in %	In training data
125438	gram-positive	gram-positiveⓘ	yes	91.81	no
125438	anaerobic	anaerobicⓘ	no	90.01	no
125438	spore-forming	spore-formingⓘ	no	81.13	no
125438	aerobic	aerobicⓘ	no	93.79	yes
125438	thermophilic	thermophileⓘ	no	95.00	no
125438	flagellated	motile2+ⓘ	no	92.00	no

Literature

Topic	Title	Authors	Journal	DOI	Year
Biotechnology	Manipulating the growth environment through co-culture to enhance stress tolerance and viability of probiotic strains in the gastrointestinal tract.	Oana K, Shimizu K, Takada T, Makino H, Yamazaki M, Katto M, Ando M, Kurakawa T, Oishi K.	Appl Environ Microbiol	10.1128/aem.01502-23	2023
	Viability-PCR for the selective detection of Lactobacillus acidophilus and Bifidobacterium bifidum in live bacteria-containing products.	Catone S, Iannantuono S, Genovese D, Von Hunolstein C, Franciosa G.	Front Microbiol	10.3389/fmicb.2024.1400529	2024
	Detection of Listeria monocytogenes in foods with a textile organic electrochemical transistor biosensor.	Vizzini P, Beltrame E, Coppede N, Vurro F, Andreatta F, Torelli E, Manzano M.	Appl Microbiol Biotechnol	10.1007/s00253-023-12543-y	2023
	Molecular patterns from a human gut-derived Lactobacillus strain suppress pathogenic infiltration of leukocytes into the central nervous system.	Sanchez JMS, Doty DJ, DePaula-Silva AB, Brown DG, Bell R, Klag KA, Truong A, Libbey JE, Round JL, Fujinami RS.	J Neuroinflammation	10.1186/s12974-020-01959-2	2020
	Cas9-independent tracrRNA cytotoxicity in Lacticaseibacillus paracasei.	Arifah AQ, Vento JM, Kurrer I, Achmedov T, Beisel CL.	Microlife	10.1093/femsml/uqaf013	2025
	Enhanced preservation of viability and species stratification in Lacticaseibacillus group using levan-fortified skim milk as a cryoprotectant during freeze-drying.	Yavuz M, Erginer M, Kasavi C, Toksoy Oner E.	Food Sci Biotechnol	10.1007/s10068-024-01802-x	2025
	Indigenous Lactic Acid Bacteria Isolated from Raw Graviera Cheese and Evaluation of Their Most Important Technological Properties.	Psomas E, Sakaridis I, Boukouvala E, Karatzia MA, Ekateriniadou LV, Samouris G.	Foods	10.3390/foods12020370	2023
	Lipid discovery enabled by sequence statistics and machine learning.	Christensen PM, Martin J, Uppuluri A, Joyce LR, Wei Y, Guan Z, Morcos F, Palmer KL.	Elife	10.7554/elife.94929	2024
	Clinical Potential of Novel Microbial Therapeutic LP51 Based on Xerosis-Microbiome Index.	Kim S, Rahim MA, Tajdozian H, Barman I, Park HA, Yoon Y, Jo S, Lee S, Shuvo MSH, Bae SH, Lee H, Ju S, Park CE, Kim HK, Han JH, Kim JW, Yoon SG, Kim JH, Choi YG, Lee S, Seo H, Song HY.	Cells	10.3390/cells13232029	2024
Biotechnology	Nanobiotechnology Unveils the Power of Probiotics: A Comprehensive Review on the Synergistic Role of Probiotics and Advanced Nanotechnology in Enhancing Geriatric Health.	Kadam O, Dalai S, Chauhan B, Guru RR, Mitra S, Raytekar N, Kumar R.	Cureus	10.7759/cureus.80478	2025
Metabolism	In Vitro Framework to Assess the Anti-Helicobacter pylori Potential of Lactic Acid Bacteria Secretions as Alternatives to Antibiotics.	Whiteside SA, Mohiuddin MM, Shlimon S, Chahal J, MacPherson CW, Jass J, Tompkins TA, Creuzenet C.	Int J Mol Sci	10.3390/ijms22115650	2021
	Linking human milk oligosaccharide metabolism and early life gut microbiota: bifidobacteria and beyond.	Lordan C, Roche AK, Delsing D, Nauta A, Groeneveld A, MacSharry J, Cotter PD, van Sinderen D.	Microbiol Mol Biol Rev	10.1128/mmbr.00094-23	2024
	Lactobacillus paracasei-derived extracellular vesicles attenuate the intestinal inflammatory response by augmenting the endoplasmic reticulum stress pathway.	Choi JH, Moon CM, Shin TS, Kim EK, McDowell A, Jo MK, Joo YH, Kim SE, Jung HK, Shim KN, Jung SA, Kim YK.	Exp Mol Med	10.1038/s12276-019-0359-3	2020
Metabolism	An Acid Up-Regulated Surface Protein of Lactobacillus paracasei Strain GCRL 46 is Phylogenetically Related to the Secreted Glucan- (GpbB) and Immunoglobulin-Binding (SibA) Protein of Pathogenic Streptococci.	Pepper SJ, Britz ML.	Int J Mol Sci	10.3390/ijms20071610	2019
	Occurrence and genetic diversity of prophage sequences identified in the genomes of L. casei group bacteria.	Jarocki P, Komon-Janczara E, Mlodzinska A, Sadurski J, Kolodzinska K, Laczmanski L, Panek J, Frac M.	Sci Rep	10.1038/s41598-023-35823-z	2023
Genetics	Genome sequence of Lacticaseibacillus paracasei ORD 0998 (CECT 30660), a probiotic bacterium for women's health.	Rodenes-Gavidia A, Illescas V, Martinez-Blanch J, Chenoll E, Moreno-Munoz JA, Jimenez Lopez J, Lamelas A.	Microbiol Resour Announc	10.1128/mra.00849-24	2025
Genetics	Genome sequence and evaluation of safety and probiotic potential of Lacticaseibacillus paracasei LC86 and Lacticaseibacillus casei LC89.	Chen T, Zhao Y, Fan Y, Dong Y, Gai Z.	Front Microbiol	10.3389/fmicb.2024.1501502	2024
	Comprehensive Safety Assessment of Lacticaseibacillus paracasei subsp. paracasei NTU 101 Through Integrated Genotypic and Phenotypic Analysis.	Chen CT, Chao WY, Lin CH, Shih TW, Pan TM.	Curr Issues Mol Biol	10.3390/cimb46110734	2024
Genetics	Lacticaseibacillus paracasei: Occurrence in the Human Gut Microbiota and K-Mer-Based Assessment of Intraspecies Diversity.	Frolova M, Yudin S, Makarov V, Glazunova O, Alikina O, Markelova N, Kolzhetsov N, Dzhelyadin T, Shcherbakova V, Trubitsyn V, Panyukov V, Zaitsev A, Kiselev S, Shavkunov K, Ozoline O.	Life (Basel)	10.3390/life11111246	2021
	Potential Probiotic Properties of Exopolysaccharide-Producing Lacticaseibacillus paracasei EPS DA-BACS and Prebiotic Activity of Its Exopolysaccharide.	Lee MG, Joeng H, Shin J, Kim S, Lee C, Song Y, Lee BH, Park HG, Lee TH, Jiang HH, Han YS, Lee BG, Lee HJ, Park MJ, Jun YJ, Park YS.	Microorganisms	10.3390/microorganisms10122431	2022
	Probiotic Properties of Lactic Acid Bacteria Newly Isolated from Algerian Raw Cow's Milk.	Kouadri Boudjelthia N, Belabbas M, Bekenniche N, Monnoye M, Gerard P, Riazi A.	Microorganisms	10.3390/microorganisms11082091	2023
	Uptake of Levilactobacillus brevis JCM 1059 by THP-1 Cells via Interaction between SlpB and CAP-1 Promotes Cytokine Production.	Yin T, Zhang X, Iwatani S, Miyanaga K, Yamamoto N.	Microorganisms	10.3390/microorganisms11020247	2023
	Lacticaseibacillus spp.; Probiotic candidates from Palmyra palm sugar possesses antimicrobial and anti-biofilm activities against methicillin-resistant Staphylococcus aureus.	Mitsuwan W, Sornsenee P, Romyasamit C.	Vet World	10.14202/vetworld.2022.299-308	2022
	Molecular strategies for the utilisation of human milk oligosaccharides by infant gut-associated bacteria.	Kiely LJ, Busca K, Lane JA, van Sinderen D, Hickey RM.	FEMS Microbiol Rev	10.1093/femsre/fuad056	2023
Proteome	Valorization of leftover green tea residues through conversion to bioactive peptides using probiotics-aided anaerobic digestion.	Lee JY, Hong H, Lee JE, Hong YJ, Hwang HW, Jin HS, Shim H, Hong YD, Park WS, Chung JO, Lee DW.	Microb Biotechnol	10.1111/1751-7915.14155	2023
Metabolism	In silico analysis of protein toxin and bacteriocins from Lactobacillus paracasei SD1 genome and available online databases.	Surachat K, Sangket U, Deachamag P, Chotigeat W.	PLoS One	10.1371/journal.pone.0183548	2017
Genetics	Genome Sequencing of five Lacticaseibacillus Strains and Analysis of Type I and II Toxin-Antitoxin System Distribution.	Levante A, Lazzi C, Vatsellas G, Chatzopoulos D, Dionellis VS, Makrythanasis P, Neviani E, Folli C.	Microorganisms	10.3390/microorganisms9030648	2021
Metabolism	Evaluation of the Cholesterol-Lowering Mechanism of Enterococcus faecium Strain 132 and Lactobacillus paracasei Strain 201 in Hypercholesterolemia Rats.	Yang L, Xie X, Li Y, Wu L, Fan C, Liang T, Xi Y, Yang S, Li H, Zhang J, Ding Y, Xue L, Chen M, Wang J, Wu Q.	Nutrients	10.3390/nu13061982	2021
Genetics	Complete Genome Sequencing and Comparative Genomics of Three Potential Probiotic Strains, Lacticaseibacillus casei FBL6, Lacticaseibacillus chiayiensis FBL7, and Lacticaseibacillus zeae FBL8.	Kim E, Yang SM, Kim D, Kim HY.	Front Microbiol	10.3389/fmicb.2021.794315	2021
Genetics	Visualization of consensus genome structure without using a reference genome.	Tada I, Tanizawa Y, Arita M.	BMC Genomics	10.1186/s12864-017-3499-7	2017
Genetics	Comparative genomics and functional analysis of a highly adhesive dairy Lactobacillus paracasei subsp. paracasei IBB3423 strain.	Koryszewska-Baginska A, Gawor J, Nowak A, Grynberg M, Aleksandrzak-Piekarczyk T.	Appl Microbiol Biotechnol	10.1007/s00253-019-10010-1	2019
	alpha-Lipoic acid increases phagocytosis of some lactic acid bacteria via modulation of CD36 expression.	Nomura N, Miyadai N, Kawase I.	Biosci Microbiota Food Health	10.12938/bmfh.2024-019	2025
	Exploring Calcium Alginate-Based Gels for Encapsulation of Lacticaseibacillus paracasei to Enhance Stability in Functional Breadmaking.	Zadeike D, Gaizauskaite Z, Basinskiene L, Zvirdauskiene R, Cizeikiene D.	Gels	10.3390/gels10100641	2024
	Lacticaseibacillus paracasei completely utilizes fructooligosacchrides in the human gut through beta-fructosidase (FosE).	Jung DH, Kim IY, Kim YJ, Chung WH, Lim MY, Nam YD, Seo DH, Park CS.	World J Microbiol Biotechnol	10.1007/s11274-024-04068-x	2024
	Isolation, structure elucidation, total synthesis, and biosynthesis of dermazolium A, an antibacterial imidazolium metabolite of a vaginal bacterium Dermabacter vaginalis.	Kim HR, Kim J, Yu JS, Lee BS, Kim KH, Kim CS.	Arch Pharm Res	10.1007/s12272-022-01424-z	2023
	Newly isolated Lactobacillus paracasei strain modulates lung immunity and improves the capacity to cope with influenza virus infection.	Kim S, Lee S, Kim TY, Lee SH, Seo SU, Kweon MN.	Microbiome	10.1186/s40168-023-01687-8	2023
	Reduction in Biogenic Amine Content in Baechu (Napa Cabbage) Kimchi by Biogenic Amine-Degrading Lactic Acid Bacteria.	Lee J, Jin YH, Pawluk AM, Mah JH.	Microorganisms	10.3390/microorganisms9122570	2021
Phylogeny	Comparison of 16S rRNA Gene Based Microbial Profiling Using Five Next-Generation Sequencers and Various Primers.	Park C, Kim SB, Choi SH, Kim S	Front Microbiol	10.3389/fmicb.2021.715500	2021
Phylogeny	Characterization of a bacterial strain Lactobacillus paracasei LP10266 recovered from an endocarditis patient in Shandong, China.	Tang Q, Hao Y, Wang L, Lu C, Li M, Si Z, Wu X, Lu Z	BMC Microbiol	10.1186/s12866-021-02253-8	2021
Genetics	Whole-genome sequence and comparative genome analysis of Lactobacillus paracasei DTA93, a promising probiotic lactic acid bacterium.	Tarrah A, Pakroo S, Corich V, Giacomini A	Arch Microbiol	10.1007/s00203-020-01883-2	2020
Phylogeny	In Vitro Evaluation of Probiotic Properties of Lactic Acid Bacteria Isolated from Some Traditionally Fermented Ethiopian Food Products.	Mulaw G, Sisay Tessema T, Muleta D, Tesfaye A	Int J Microbiol	10.1155/2019/7179514	2019
Enzymology	Probiotic Lactobacillus paracasei A221 improves the functionality and bioavailability of kaempferol-glucoside in kale by its glucosidase activity.	Shimojo Y, Ozawa Y, Toda T, Igami K, Shimizu T	Sci Rep	10.1038/s41598-018-27532-9	2018
Pathogenicity	Stabilization of freeze-dried Lactobacillus paracasei subsp. paracasei JCM 8130(T) with the addition of disaccharides, polymers, and their mixtures.	Teng D, Kawai K, Mikajiri S, Hagura Y	Biosci Biotechnol Biochem	10.1080/09168451.2017.1279852	2017
Enzymology	Antibacterial activity of a cell wall hydrolase from Lactobacillus paracasei NRRL B-50314 produced by recombinant Bacillus megaterium.	Liu S, Rich JO, Anderson A	J Ind Microbiol Biotechnol	10.1007/s10295-014-1557-6	2014
Phylogeny	Isolation and identification of lactic acid bacteria with effect of immune protection to Eschericia coli in mice.	Ishida-Fujii K, Goto S, Kuboki H, Hirano S, Sakamoto M, Sato M	Biofactors	10.1002/biof.552210131	2004
Phylogeny	Comparative sequence analysis of a recA gene fragment brings new evidence for a change in the taxonomy of the Lactobacillus casei group.	Felis GE, Dellaglio F, Mizzi L, Torriani S	Int J Syst Evol Microbiol	10.1099/00207713-51-6-2113	2001
Biotechnology	Accelerated production of dry fermented sausage.	Blom H, Hagen BF, Pedersen BO, Holck AL, Axelsson L, Naes H	Meat Sci	10.1016/0309-1740(96)00068-x	1996
Enzymology	Cloning, sequencing and expression of the gene encoding the cell-envelope-associated proteinase from Lactobacillus paracasei subsp. paracasei NCDO 151.	Holck A, Naes H	J Gen Microbiol	10.1099/00221287-138-7-1353	1992
Enzymology	Purification and N-terminal amino acid sequence determination of the cell-wall-bound proteinase from Lactobacillus paracasei subsp. paracasei.	Naes H, Nissen-Meyer J	J Gen Microbiol	10.1099/00221287-138-2-313	1992
Biotechnology	Lactobacilli isolated from sugary kefir grains capable of polysaccharide production and minicell formation.	Pidoux M, Marshall VM, Zanoni P, Brooker B	J Appl Bacteriol	10.1111/j.1365-2672.1990.tb01521.x	1990
Phylogeny	Lactobacillus brantae sp. nov., isolated from faeces of Canada geese (Branta canadensis).	Volokhov DV, Amselle M, Beck BJ, Popham DL, Whittaker P, Wang H, Kerrigan E, Chizhikov VE	Int J Syst Evol Microbiol	10.1099/ijs.0.033852-0	2011

References

#2263	Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 5622
#20215	Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 )
#20218	Verslyppe, B., De Smet, W., De Baets, B., De Vos, P., Dawyndt P.: StrainInfo introduces electronic passports for microorganisms.. Syst Appl Microbiol. 37: 42 - 50 2014 ( DOI 10.1016/j.syapm.2013.11.002 , PubMed 24321274 )
#34920	; Curators of the CIP;
#50901	Culture Collection University of Gothenburg (CCUG) ; Curators of the CCUG; CCUG 32212
#66792	Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) .
#67770	Japan Collection of Microorganism (JCM) ; Curators of the JCM;
#68371	Automatically annotated from API 50CH acid .
#68382	Automatically annotated from API zym .
#69479	João F Matias Rodrigues, Janko Tackmann,Gregor Rot, Thomas SB Schmidt, Lukas Malfertheiner, Mihai Danaila,Marija Dmitrijeva, Daniela Gaio, Nicolas Näpflin and Christian von Mering. University of Zurich.: MicrobeAtlas 1.0 beta .
#121547	Collection of Institut Pasteur ; Curators of the CIP; CIP 103918
#124043	Isabel Schober, Julia Koblitz: Data extracted from sequence databases, automatically matched based on designation and taxonomy .
#125438	Julia Koblitz, Lorenz Christian Reimer, Rüdiger Pukall, Jörg Overmann: Predicting bacterial phenotypic traits through improved machine learning using high-quality, curated datasets. 2024 ( DOI 10.1101/2024.08.12.607695 )
#125439	Philipp Münch, René Mreches, Martin Binder, Hüseyin Anil Gündüz, Xiao-Yin To, Alice McHardy: deepG: Deep Learning for Genome Sequence Data. R package version 0.3.1 .
#126262	A. Lissin, I. Schober, J. F. Witte, H. Lüken, A. Podstawka, J. Koblitz, B. Bunk, P. Dawyndt, P. Vandamme, P. de Vos, J. Overmann, L. C. Reimer: StrainInfo—the central database for linked microbial strain identifiers. ( DOI 10.1093/database/baaf059 )

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Lacticaseibacillus paracasei subsp. paracasei (DSM 5622, ATCC 25302, NCDO 151)

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