Lactobacillus delbrueckii subsp. lactis (DSM 20355, ATCC 7830, NCDO 8118)

Name: Lactobacillus delbrueckii subsp. lactis (DSM 20355, ATCC 7830, NCDO 8118)
Creator: BacDive
License: http://creativecommons.org/licenses/by/4.0/

BacDive ID 6454

Type strain

Strain Designation 313, Ld 5, Ld5

Culture col. no. DSM 20355 ATCC 7830 NCDO 8118 NCIB 302 313 17 more

NCBI tax ID(s) 29397

Special Collections DSMZ CCUG JCM KCTC CIP

Links

Lactobacillus delbrueckii subsp. lactis 313 is an anaerobe, mesophilic, Gram-positive prokaryote of the family Lactobacillaceae.

Gram-positive rod-shaped anaerobe mesophilic genome sequence 16S sequence

Name and taxonomic classification

SI-ID 8913

LMG 5855,ATCC 7830,LMG 6401,CECT 282,IAM 12066,IFO 3376,JCM 1557,NCFB 302,NCIMB 8118,NCDO 302,NCIB 8118,CCUG 19776,NCDO 8118,NCIB 302,CCRC 11051,KCTC 1058,KCTC 3035,CCM 2772,NCAIM B.01472,CIP 53.61,LMD 49.7,CCRC 14067,CCUG 28153 C,NBRC 3376,NCCB 49007,BCRC 11051,BCRC 14067,NCFB 8118,CCT 2578,NCIM 2071,CDBB 1053,CGMCC 1.0139,CGMCC 1.2142,DSM 20355,CNCTC 7

@ref 20215

Last LPSN update 2025-12-16 09:48:19

Domain Bacillati

Phylum Bacillota

Class Bacilli

Order Lactobacillales

Family Lactobacillaceae

Genus Lactobacillus

Species Lactobacillus delbrueckii subsp. lactis

Full scientific name Lactobacillus delbrueckii subsp. lactis (Orla-Jensen 1919) Weiss et al. 1984

Synonyms (2)

"Thermobacterium lactis"
Lactobacillus lactis

BacDive ID	Other strains from **Lactobacillus delbrueckii subsp. lactis** (15)	Type strain
6451	L. delbrueckii subsp. lactis L 110, DSM 20072, ATCC 12315, NCDO 1438, ... (type strain)
6452	L. delbrueckii subsp. lactis 14-1, L 889, DSM 20073, ATCC 14933
6453	L. delbrueckii subsp. lactis 326, F 59, DSM 20076, ATCC 4797, CCM 2344, ...
135973	L. delbrueckii subsp. lactis CIP 101810
137310	L. delbrueckii subsp. lactis MB 367, CIP 105924, ATCC 10697, JCM 1107, ...
139021	L. delbrueckii subsp. lactis 103-76, CIP 110109
139036	L. delbrueckii subsp. lactis CIP 57.5, ATCC 8000, IAM 1173, JCM 1105, ...
142103	L. delbrueckii subsp. lactis CCUG 10909
145767	L. delbrueckii subsp. lactis CCUG 29538
150308	L. delbrueckii subsp. lactis CCUG 39595
155777	L. delbrueckii subsp. lactis CCUG 59286
160874	L. delbrueckii subsp. lactis JCM 1010, BCRC 14032
160882	L. delbrueckii subsp. lactis JCM 1016
161008	L. delbrueckii subsp. lactis JCM 1063, BCRC 14033
161126	L. delbrueckii subsp. lactis JCM 1106

Morphology

Cell morphology

@ref	Gram stain	Cell shape
118881	positive	rod-shaped
125438
125438	positive

Culture and growth conditions

Culture medium

@ref	Name	Medium link	Composition
8617	PEDIOCOCCUS DAMNOSUS MEDIUM (DSMZ Medium 231)	Medium recipe at MediaDive	Name: PEDIOCOCCUS DAMNOSUS MEDIUM (DSMZ Medium 231) Composition: Glucose 20.0 g/l Casein peptone 10.0 g/l Meat extract 10.0 g/l Yeast extract 5.0 g/l Na-acetate 5.0 g/l K2HPO4 2.0 g/l (NH4)3 citrate 2.0 g/l Tween 80 1.0 g/l Cysteine hydrochloride 0.5 g/l MgSO4 x 7 H2O 0.2 g/l MnSO4 x H2O 0.05 g/l Distilled water
8617	MRS MEDIUM (DSMZ Medium 11)	Medium recipe at MediaDive	Name: MRS MEDIUM (DSMZ Medium 11) Composition: Glucose 20.0 g/l Casein peptone 10.0 g/l Meat extract 10.0 g/l Na-acetate 5.0 g/l Yeast extract 5.0 g/l (NH4)3 citrate 2.0 g/l K2HPO4 2.0 g/l Tween 80 1.0 g/l MgSO4 x 7 H2O 0.2 g/l MnSO4 x H2O 0.05 g/l Distilled water
34200	MEDIUM 40- for Lactobacillus and Leuconostoc		Distilled water make up to (1000.000 ml);Man Rogosa Sharp agar (68.000 g)
118881	CIP Medium 40	Medium recipe at CIP

Culture temp

@ref	Growth	Type	Temperature (°C)	Range
8617	positive	growth	37	mesophilic
34200	positive	growth	37	mesophilic
67770	positive	growth	37	mesophilic
118881	positive	growth	30-45
118881	negative	growth	10
118881	negative	growth	15

Physiology and metabolism

Oxygen tolerance

@ref	Oxygen tolerance
8617	anaerobe
8617	microaerophile
118881	facultative anaerobe
125439	anaerobe

Spore formation

@ref	Spore formation	Confidence
125439		95.3

Murein

@ref	Murein short key	Type
8617	A11.31	A4alpha L-Lys-D-Asp

Observation

67770

ObservationAssay of Vitamin B12

Metabolite utilization

@ref	Chebi-ID	Metabolite	Utilization activity	Kind of utilization tested
68371	17108 ChEBI	D-arabinose	-	builds acid from	from API 50CH acid
68371	18333 ChEBI	D-arabitol	-	builds acid from	from API 50CH acid
68371	28847 ChEBI	D-fucose	-	builds acid from	from API 50CH acid
68371	12936 ChEBI	D-galactose	-	builds acid from	from API 50CH acid
68371	17634 ChEBI	D-glucose	+	builds acid from	from API 50CH acid
68371	62318 ChEBI	D-lyxose	-	builds acid from	from API 50CH acid
68371	16899 ChEBI	D-mannitol	-	builds acid from	from API 50CH acid
68371	16024 ChEBI	D-mannose	+	builds acid from	from API 50CH acid
68371	16988 ChEBI	D-ribose	-	builds acid from	from API 50CH acid
68371	17924 ChEBI	D-sorbitol	-	builds acid from	from API 50CH acid
68371	16443 ChEBI	D-tagatose	-	builds acid from	from API 50CH acid
68371	65327 ChEBI	D-xylose	-	builds acid from	from API 50CH acid
68371	17113 ChEBI	erythritol	-	builds acid from	from API 50CH acid
68371	4853 ChEBI	esculin	+	builds acid from	from API 50CH acid
68371	16813 ChEBI	galactitol	-	builds acid from	from API 50CH acid
68371	24265 ChEBI	gluconate	-	builds acid from	from API 50CH acid
68371	17754 ChEBI	glycerol	-	builds acid from	from API 50CH acid
68371	28087 ChEBI	glycogen	-	builds acid from	from API 50CH acid
68371	15443 ChEBI	inulin	-	builds acid from	from API 50CH acid
68371	30849 ChEBI	L-arabinose	-	builds acid from	from API 50CH acid
68371	18403 ChEBI	L-arabitol	-	builds acid from	from API 50CH acid
68371	18287 ChEBI	L-fucose	-	builds acid from	from API 50CH acid
68371	62345 ChEBI	L-rhamnose	-	builds acid from	from API 50CH acid
68371	17266 ChEBI	L-sorbose	-	builds acid from	from API 50CH acid
68371	65328 ChEBI	L-xylose	-	builds acid from	from API 50CH acid
68371	6731 ChEBI	melezitose	-	builds acid from	from API 50CH acid
68371	28053 ChEBI	melibiose	-	builds acid from	from API 50CH acid
68371	320061 ChEBI	methyl alpha-D-glucopyranoside	-	builds acid from	from API 50CH acid
68371	43943 ChEBI	methyl alpha-D-mannoside	-	builds acid from	from API 50CH acid
68371	74863 ChEBI	methyl beta-D-xylopyranoside	-	builds acid from	from API 50CH acid
68371	17268 ChEBI	myo-inositol	-	builds acid from	from API 50CH acid
118881	17632 ChEBI	nitrate	-	reduction
118881	17632 ChEBI	nitrate	+	respiration
118881	16301 ChEBI	nitrite	-	reduction
68371		Potassium 2-ketogluconate	-	builds acid from	from API 50CH acid
68371		Potassium 5-ketogluconate	-	builds acid from	from API 50CH acid
68371	16634 ChEBI	raffinose	-	builds acid from	from API 50CH acid
68371	15963 ChEBI	ribitol	-	builds acid from	from API 50CH acid
68371	28017 ChEBI	starch	-	builds acid from	from API 50CH acid
68371	17992 ChEBI	sucrose	+	builds acid from	from API 50CH acid
68371	32528 ChEBI	turanose	-	builds acid from	from API 50CH acid
68371	17151 ChEBI	xylitol	-	builds acid from	from API 50CH acid

Metabolite tests

@ref	Chebi-ID	Metabolite	Voges-proskauer-test
118881	15688 ChEBI	acetoin	-

Enzymes

@ref	Value	Activity	Ec
68382	acid phosphatase	+	3.1.3.2	from API zym
118881	alcohol dehydrogenase	+	1.1.1.1
68382	alkaline phosphatase	-	3.1.3.1	from API zym
68382	alpha-chymotrypsin	+	3.4.21.1	from API zym
68382	alpha-fucosidase	-	3.2.1.51	from API zym
68382	alpha-galactosidase	-	3.2.1.22	from API zym
68382	alpha-glucosidase	-	3.2.1.20	from API zym
68382	alpha-mannosidase	-	3.2.1.24	from API zym
68382	beta-galactosidase	+	3.2.1.23	from API zym
68382	beta-glucosidase	+	3.2.1.21	from API zym
68382	beta-glucuronidase	-	3.2.1.31	from API zym
118881	catalase	-	1.11.1.6
68382	cystine arylamidase	-	3.4.11.3	from API zym
68382	esterase (C 4)	+		from API zym
68382	esterase lipase (C 8)	+		from API zym
68382	leucine arylamidase	+	3.4.11.1	from API zym
68382	lipase (C 14)	-		from API zym
118881	lysine decarboxylase	-	4.1.1.18
68382	N-acetyl-beta-glucosaminidase	-	3.2.1.52	from API zym
68382	naphthol-AS-BI-phosphohydrolase	+		from API zym
118881	ornithine decarboxylase	-	4.1.1.17
118881	oxidase	-
68382	trypsin	-	3.4.21.4	from API zym
68382	valine arylamidase	-		from API zym

API zym

@ref	Control	Alkaline phosphatase	Esterase (C 4)	2-naphtyl caprylateEsterase Lipase (C 8)	Lipase (C 14)	L-leucyl-2-naphthylamideLeucine arylamidase	L-valyl-2-naphthylamideValine arylamidase	L-cystyl-2-naphthylamideCystine arylamidase	Trypsin	alpha- Chymotrypsin	Acid phosphatase	Naphthol-AS-BI-phosphateNaphthol-AS-BI-phosphohydrolase	alpha- Galactosidase	beta- Galactosidase	beta- Glucuronidase	alpha- Glucosidase	beta- Glucosidase	N-acetyl-beta- glucosaminidase	alpha- Mannosidase	alpha- Fucosidase
118881	-	-	+	+	-	+	-	-	-	+	+	+	-	+	-	-	+	-	-	-

API 50CHac

@ref	ControlQ	GLY	ERY	DARA	LARA	RIB	DXYL	LXYL	ADO	MDX	GAL	GLU	FRU	MNE	SBE	RHA	DUL	INO	MAN	SOR	MDM	MDG	NAG	AMY	ARB	ESC	SAL	CEL	MAL	LAC	MEL	SAC	TRE	INU	MLZ	RAF	AMD	GLYG	XLT	GEN	TUR	LYX	TAG	DFUC	LFUC	DARL	LARL	GNT	2KG	5KG
8617	-	-	-	-	-	-	-	-	-	-	-	+	+	+	-	-	-	-	-	-	-	-	-	-	-	+	-	-	-	-	-	+	+	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
8617	-	-	-	-	-	-	-	-	-	-	-	+	+	+	-	-	-	-	-	-	-	-	+	+	-	+	-	+	+	+	-	+	+	-	-	-	-	-	-	+	-	-	-	-	-	-	-	-	-	-
8617	-	-	-	-	-	-	-	-	-	-	-	+	+/-	+	-	-	-	-	-	-	-	-	-	-	-	+	-	-	-	-	-	+	+/-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
118881	not determinedn.d.	-	-	-	-	-	-	-	-	-	-	+	+	+	-	-	-	-	-	-	-	-	-	+	+	+	+	+	+	+	-	+	+	-	-	-	-	-	-	+	-	-	-	-	-	-	-	-	-	-

API biotype100

@ref	ControlQ	D-glucose as carbon sourceGLU	D-fructose as carbon sourceFRU	D-galactose as carbon sourceGAL	D-trehalose as carbon sourceTRE	D-mannose as carbon sourceMNE	L-sorbose as carbon sourceSBE	D-melibiose as carbon sourceMEL	sucrose as carbon sourceSAC	D-raffinose as carbon sourceRAF	maltotriose as carbon sourceMTE	maltose as carbon sourceMAL	lactose as carbon sourceLAC	lactulose as carbon sourceLTE	1-O-methyl-beta-galactopyranoside as carbon sourceMbGa	1-O-methyl-alpha-galactopyranoside as carbon sourceMaGa	D-cellobiose as carbon sourceCEL	gentiobiose as carbon sourceGEN	1-O-methyl-beta-D-glucopyranoside as carbon sourceMbGu	esculin as carbon sourceESC	D-ribose as carbon sourceRIB	L-arabinose as carbon sourceARA	D-xylose as carbon sourceXYL	palatinose as carbon sourcePLE	L-rhamnose as carbon sourceRHA	L-fucose as carbon sourceFUC	D-melezitose as carbon sourceMLZ	D-arabitol as carbon sourceDARL	L-arabitol as carbon sourceLARL	xylitol as carbon sourceXLT	dulcitol as carbon sourceDUL	D-tagatose as carbon sourceTAG	glycerol as carbon sourceGLY	myo-inositol as carbon sourceINO	D-mannitol as carbon sourceMAN	maltitol as carbon sourceMTL	D-turanose as carbon sourceTUR	D-sorbitol as carbon sourceSOR	adonitol as carbon sourceADO	hydroxyquinoline-beta-glucuronide as carbon sourceHBG	D-lyxose as carbon sourceLYX	i-erythritol as carbon sourceERY	1-O-methyl-alpha-D-glucoside as carbon sourceMDG	3-O-methyl-D-glucose as carbon source3MDG	D-saccharate as carbon sourceSAT	mucate as carbon sourceMUC	L-tartrate as carbon sourceLTAT	D-tartrate as carbon sourceDTAT	meso-tartrate as carbon sourceMTAT	D-malate as carbon sourceDMLT	L-malate as carbon sourceLMLT	cis-aconitate as carbon sourceCATE	trans-aconitate as carbon sourceTATE	tricarballylate as carbon sourceTTE	citrate as carbon sourceCIT	D-glucuronate as carbon sourceGRT	D-galacturonate as carbon sourceGAT	2-ketogluconate as carbon source2KG	5-ketogluconate as carbon source5KG	tryptophan as carbon sourceTRY	N-acetyl-D-glucosamine as carbon sourceNAG	D-gluconate as carbon sourceGNT	phenylacetate as carbon sourcePAC	protocatechuate as carbon sourcePAT	4-hydroxybenzoate as carbon sourcepOBE	quinate as carbon sourceQAT	gentisate as carbon sourceGTE	3-hydroxybenzoate as carbon sourcemOBE	benzoate as carbon sourceBAT	3-phenylpropionate as carbon sourcePPAT	m-coumarate as carbon sourceCMT	trigonelline as carbon sourceTGE	betaine as carbon sourceBET	putrescine as carbon sourcePCE	4-aminobutyrate as carbon sourceABT	histamine as carbon sourceHIN	DL-lactate as carbon sourceLAT	caprate as carbon sourceCAP	caprylate as carbon sourceCYT	L-histidine as carbon sourceHIS	succinate as carbon sourceSUC	fumarate as carbon sourceFUM	glutarate as carbon sourceGRE	DL-glycerate as carbon sourceGYT	5-aminovalerate as carbon sourceAVT	ethanolamine as carbon sourceETN	tryptamine as carbon sourceTTN	D-glucosamine as carbon sourceGLN	itaconate as carbon sourceITA	3-hydroxybutyrate as carbon source3OBU	L-aspartate as carbon sourceAPT	L-glutamate as carbon sourceGTT	L-proline as carbon sourcePRO	D-alanine as carbon sourceDALA	L-alanine as carbon sourceLALA	L-serine as carbon sourceSER	malonate as carbon sourceMNT	propionate as carbon sourcePROP	L-tyrosine as carbon sourceTYR	2-ketoglutarate as carbon source2KT
118881	not determinedn.d.	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-

Isolation, sampling and environmental information

Interaction and safety

Risk assessment

@ref	Biosafety level	Biosafety level comment
8617	1	Risk group (German classification) According to TRBA 466
118881	1	Risk group (French classification) According to TRBA 466

Sequence information

Genome sequences

@ref	Description	Assembly level	INSDC accession	BV-BRC accession	IMG accession	NCBI tax ID	Score
66792	ASM188898v1 assembly for Lactobacillus delbrueckii subsp. lactis KCTC 3035	complete	GCA_001888985	29397.16	2718218337	29397	96.22
67770	ASM653862v1 assembly for Lactobacillus delbrueckii subsp. lactis NBRC 3376	contig	GCA_006538625	29397.69		29397	58.85
66792	ASM2113447v1 assembly for Lactobacillus delbrueckii subsp. lactis DSM 20355	contig	GCA_021134475	29397.134		29397	49.61

Genome browser: GCA_001888985

16S sequences

@ref	Description	Accession	Length	NCBI tax ID
124043	Lactobacillus delbrueckii subsp. lactis gene for 16S rRNA, partial sequence, strain: JCM 1557.	AB289095	675	29397
124043	Lactobacillus delbrueckii subsp. lactis gene for 16S rRNA, partial sequence, strain: NBRC 3376.	AB680073	1489	29397
124043	Lactobacillus delbrueckii subsp. lactis strain BCRC11051 16S ribosomal RNA gene, complete sequence.	AY773950	1516	29397
124043	Lactobacillus delbrueckii subsp. lactis NBRC3376 gene for 16S rRNA, partial sequence.	LC685611	1435	29397

GC content

8617

GC-content (mol%)50.5

Genome-based predictions

Predictions

Predictions from Deep Learning for Genome Sequence Data. R package version 0.3.1 based on: Lactobacillus delbrueckii subsp. lactis KCTC 3035
NCBI: GCA_001888985

@ref	Trait	Model	Prediction	Confidence in %	In training data
125439	spore_formation	BacteriaNetⓘ	no	95.30	no
125439	motility	BacteriaNetⓘ	no	73.90	no
125439	gram_stain	BacteriaNetⓘ	negative	71.20	no
125439	oxygen_tolerance	BacteriaNetⓘ	anaerobe	99.50	no

Predictions from bacterial phenotypic traits through improved machine learning using high-quality, curated datasets based on: Lactobacillus delbrueckii subsp. lactis KCTC 3035
NCBI: GCA_001888985.1

@ref	Trait	Model	Prediction	Confidence in %	In training data
125438	gram-positive	gram-positiveⓘ	yes	94.25	no
125438	anaerobic	anaerobicⓘ	no	78.01	no
125438	aerobic	aerobicⓘ	no	97.74	yes
125438	spore-forming	spore-formingⓘ	no	88.83	no
125438	thermophilic	thermophileⓘ	no	95.00	no
125438	flagellated	motile2+ⓘ	no	95.50	no

Literature

Topic	Title	Authors	Journal	DOI	Year
Genetics	Antimicrobial Susceptibility of Lactobacillus delbrueckii subsp. lactis from Milk Products and Other Habitats.	Shani N, Oberhaensli S, Berthoud H, Schmidt RS, Bachmann HP.	Foods	10.3390/foods10123145	2021
Metabolism	Cobalamin is produced by Acetobacter pasteurianus DSM 3509.	Bernhardt C, Zhu X, Schutz D, Fischer M, Bisping B.	Appl Microbiol Biotechnol	10.1007/s00253-019-09704-3	2019
	Exploiting Potential Probiotic Lactic Acid Bacteria Isolated from Chlorella vulgaris Photobioreactors as Promising Vitamin B12 Producers.	Ribeiro M, Maciel C, Cruz P, Darmancier H, Nogueira T, Costa M, Laranjeira J, Morais RMSC, Teixeira P.	Foods	10.3390/foods12173277	2023
	Functionalisation of vitamin B₁₂ derivatives with a cobalt beta-phenyl ligand boosters antimetabolite activity in bacteria.	Brenig C, Mestizo PD, Zelder F.	RSC Adv	10.1039/d2ra05748d	2022
	Pseudovitamin B₁₂ producing Loigolactobacillus coryniformis enhances soy milk fermentation by Lactobacillus delbrueckii subsp. bulgaricus.	Tsuda H, Iwai K, Hayashizaki N.	J Sci Food Agric	10.1002/jsfa.14239	2025
	Lactic Acid Production from Sugarcane Bagasse Hydrolysates by Lactiplantibacillus Strains.	Xavier MCA, Dias GS, Hernalsteens S, Franco TT.	ACS Omega	10.1021/acsomega.5c08221	2025
	Comparative Analysis of Lactobacillus Starter Cultures in Fermented Camel Milk: Effects on Viability, Antioxidant Properties, and Sensory Characteristics.	Shori AB.	Foods	10.3390/foods13223711	2024
Metabolism	Pseudovitamin B₁₂ and factor S are the predominant corrinoid compounds in edible cricket products.	Okamoto N, Nagao F, Umebayashi Y, Bito T, Prangthip P, Watanabe F.	Food Chem	10.1016/j.foodchem.2021.129048	2021
	Determination and characterization of vitamin B12 compounds in edible sea snails, ivory shell Babylonia japonica and turban shell Turdo Batillus cornutus	Teng F, Tanioka Y, Hamaguchi N, Bito T, Takenaka S, Yabuta Y, Watanabe F.	Fish Sci	10.1007/s12562-015-0920-5	2015
	Food Additives (Hypochlorous Acid Water, Sodium Metabisulfite, and Sodium Sulfite) Strongly Affect the Chemical and Biological Properties of Vitamin B₁₂ in Aqueous Solution.	Okamoto N, Bito T, Hiura N, Yamamoto A, Iida M, Baba Y, Fujita T, Ishihara A, Yabuta Y, Watanabe F.	ACS Omega	10.1021/acsomega.0c00425	2020
	Vitamin B12[c-lactone], a biologically inactive corrinoid compound, occurs in cultured and dried lion's mane mushroom (Hericium erinaceus) fruiting bodies.	Teng F, Bito T, Takenaka S, Yabuta Y, Watanabe F.	J Agric Food Chem	10.1021/jf404463v	2014
Genetics	Comparative Genomics Guides Elucidation of Vitamin B₁₂ Biosynthesis in Novel Human-Associated Akkermansia Strains.	Kirmiz N, Galindo K, Cross KL, Luna E, Rhoades N, Podar M, Flores GE.	Appl Environ Microbiol	10.1128/aem.02117-19	2020
Metabolism	Insight into the bovine milk peptide LPcin-YK3 selection in the proteolytic system of Lactobacillus species.	Sung WY, Yu JW, Hwang JT, Nam HJ, Park JY, Kim Y, Cho JH.	J Pept Sci	10.1002/psc.3268	2020
	Current Perspective of Sialylated Milk Oligosaccharides in Mammalian Milk: Implications for Brain and Gut Health of Newborns.	Hobbs M, Jahan M, Ghorashi SA, Wang B.	Foods	10.3390/foods10020473	2021
	Molecular identification of Lactobacillus spp. associated with puba, a Brazilian fermented cassava food.	Crispim SM, Nascimento AM, Costa PS, Moreira JL, Nunes AC, Nicoli JR, Lima FL, Mota VT, Nardi RM.	Braz J Microbiol	10.1590/s1517-83822013005000007	2013
Metabolism	Lactobacillus rossiae, a vitamin B12 producer, represents a metabolically versatile species within the Genus Lactobacillus.	De Angelis M, Bottacini F, Fosso B, Kelleher P, Calasso M, Di Cagno R, Ventura M, Picardi E, van Sinderen D, Gobbetti M.	PLoS One	10.1371/journal.pone.0107232	2014
Enzymology	Purification and characterization of corrinoid-compounds from the dried powder of an edible cyanobacterium, Nostoc commune (Ishikurage).	Watanabe F, Tanioka Y, Miyamoto E, Fujita T, Takenaka H, Nakano Y.	J Nutr Sci Vitaminol (Tokyo)	10.3177/jnsv.53.183	2007
	Health Benefits of Consuming Foods with Bacterial Probiotics, Postbiotics, and Their Metabolites: A Review.	Vera-Santander VE, Hernandez-Figueroa RH, Jimenez-Munguia MT, Mani-Lopez E, Lopez-Malo A.	Molecules	10.3390/molecules28031230	2023
Metabolism	Light Response of Pseudomonas putida KT2440 Mediated by Class II LitR, a Photosensor Homolog.	Sumi S, Mutaguchi N, Ebuchi T, Tsuchida H, Yamamoto T, Suzuki M, Natsuka C, Shiratori-Takano H, Shintani M, Nojiri H, Ueda K, Takano H.	J Bacteriol	10.1128/jb.00146-20	2020
	In silico Prediction, in vitro Antibacterial Spectrum, and Physicochemical Properties of a Putative Bacteriocin Produced by Lactobacillus rhamnosus Strain L156.4.	Oliveira LC, Silveira AMM, Monteiro AS, Dos Santos VL, Nicoli JR, Azevedo VAC, Soares SC, Dias-Souza MV, Nardi RMD.	Front Microbiol	10.3389/fmicb.2017.00876	2017
	Screening of lactic acid bacteria from vacuum packaged beef for antimicrobial activity.	Oliveira RB, de L Oliveira A, Gloria MB.	Braz J Microbiol	10.1590/s1517-838220080002000031	2008
Enzymology	A dodecylamine derivative of cyanocobalamin potently inhibits the activities of cobalamin-dependent methylmalonyl-CoA mutase and methionine synthase of Caenorhabditis elegans.	Bito T, Yabuta Y, Ichiyanagi T, Kawano T, Watanabe F.	FEBS Open Bio	10.1016/j.fob.2014.07.008	2014
Biotechnology	High-Level folate production in fermented foods by the B12 producer Lactobacillus reuteri JCM1112.	Santos F, Wegkamp A, de Vos WM, Smid EJ, Hugenholtz J.	Appl Environ Microbiol	10.1128/aem.02719-07	2008
Metabolism	Unexpected specificity of interspecies cobamide transfer from Geobacter spp. to organohalide-respiring Dehalococcoides mccartyi strains.	Yan J, Ritalahti KM, Wagner DD, Loffler FE.	Appl Environ Microbiol	10.1128/aem.01535-12	2012
	In situ production of active vitamin B12 in cereal matrices using Propionibacterium freudenreichii.	Chamlagain B, Sugito TA, Deptula P, Edelmann M, Kariluoto S, Varmanen P, Piironen V.	Food Sci Nutr	10.1002/fsn3.528	2018
Metabolism	Thermotoga lettingae can salvage cobinamide to synthesize vitamin B12.	Butzin NC, Secinaro MA, Swithers KS, Gogarten JP, Noll KM.	Appl Environ Microbiol	10.1128/aem.01800-13	2013
	Vitamin B12 deficiency in Caenorhabditis elegans results in loss of fertility, extended life cycle, and reduced lifespan.	Bito T, Matsunaga Y, Yabuta Y, Kawano T, Watanabe F.	FEBS Open Bio	10.1016/j.fob.2013.01.008	2013
Metabolism	Competitive selection of lactic acid bacteria that persist in the human oral cavity.	Snel J, Marco ML, Kingma F, Noordman WM, Rademaker J, Kleerebezem M.	Appl Environ Microbiol	10.1128/aem.06043-11	2011
	Vitamin B(12) and folic acid imbalance modifies NK cytotoxicity, lymphocytes B and lymphoprolipheration in aged rats.	Partearroyo T, Ubeda N, Montero A, Achon M, Varela-Moreiras G.	Nutrients	10.3390/nu5124836	2013
Metabolism	Vitamin B(12) synthesis and salvage pathways were acquired by horizontal gene transfer to the Thermotogales.	Swithers KS, Petrus AK, Secinaro MA, Nesbo CL, Gogarten JP, Noll KM, Butzin NC.	Genome Biol Evol	10.1093/gbe/evs057	2012
Metabolism	Guided cobalamin biosynthesis supports Dehalococcoides mccartyi reductive dechlorination activity.	Yan J, Im J, Yang Y, Loffler FE.	Philos Trans R Soc Lond B Biol Sci	10.1098/rstb.2012.0320	2013
Phylogeny	Use of conserved randomly amplified polymorphic DNA (RAPD) fragments and RAPD pattern for characterization of Lactobacillus fermentum in Ghanaian fermented maize dough.	Hayford AE, Petersen A, Vogensen FK, Jakobsen M.	Appl Environ Microbiol	10.1128/aem.65.7.3213-3221.1999	1999
Metabolism	Effect of amino acid availability on vitamin B12 production in Lactobacillus reuteri.	Santos F, Teusink B, Molenaar D, van Heck M, Wels M, Sieuwerts S, de Vos WM, Hugenholtz J.	Appl Environ Microbiol	10.1128/aem.02487-08	2009
Metabolism	Further studies on the binding of vitamin B 12 to the cell wall of a B 12 -requiring Lactobacillus.	Sasaki T.	J Bacteriol	10.1128/jb.109.1.169-178.1972	1972
Genetics	Genome mining approach reveals the CRISPR-Cas systems features and characteristics in Lactobacillus delbrueckii strains.	Panahi B, Rostampour M, Ghaffari MR, Nami Y.	Heliyon	10.1016/j.heliyon.2024.e39920	2024
	In Silico Comparative Genomic Analysis Revealed a Highly Conserved Proteolytic System in Lactobacillus delbrueckii.	Elean M, Albarracin L, Villena J, Kitazawa H, Saavedra L, Hebert EM.	Int J Mol Sci	10.3390/ijms241411309	2023
	Genomic Characterization of Wild Lactobacillus delbrueckii Strains Reveals Low Diversity but Strong Typicity.	Grizon A, Theil S, Helinck S, Gerber P, Bonnarme P, Chassard C.	Microorganisms	10.3390/microorganisms12030512	2024
	Comparison of Activity of Commercial Protective Cultures and Thermophilic Lactic Acid Bacteria against Listeria monocytogenes: A New Perspective to Improve the Safety of Sardinian PDO Cheeses.	Meloni MP, Piras F, Siddi G, Cabras D, Comassi E, Lai R, McAuliffe O, De Santis EPL, Scarano C.	Foods	10.3390/foods12061182	2023
Genetics	Subspecies-level genome comparison of Lactobacillus delbrueckii.	Baek MG, Kim KW, Yi H.	Sci Rep	10.1038/s41598-023-29404-3	2023
Genetics	In Silico Probiogenomic Characterization of Lactobacillus delbrueckii subsp. lactis A4 Strain Isolated from an Armenian Honeybee Gut.	Bazukyan I, Georgieva-Miteva D, Velikova T, Dimov SG.	Insects	10.3390/insects14060540	2023
Genetics	Draft genome sequence of Lactobacillus delbrueckii subsp. bulgaricus LBP UFSC 2230: a tool for preliminary identification of enzymes involved in CLA metabolism.	Kuhl GC, Mazzon RR, Duarte RTD, De Dea Lindner J.	Braz J Microbiol	10.1007/s42770-021-00479-2	2021
Genetics	Metagenomic analysis of soybean endosphere microbiome to reveal signatures of microbes for health and disease.	Chouhan U, Gamad U, Choudhari JK.	J Genet Eng Biotechnol	10.1186/s43141-023-00535-4	2023
	Probiogenomics of Lactobacillus delbrueckii subsp. lactis CIDCA 133: In Silico, In Vitro, and In Vivo Approaches.	de Jesus LCL, Drumond MM, Aburjaile FF, Sousa TJ, Coelho-Rocha ND, Profeta R, Brenig B, Mancha-Agresti P, Azevedo V.	Microorganisms	10.3390/microorganisms9040829	2021
Genetics	Differentiation of Lacticaseibacillus zeae Using Pan-Genome Analysis and Real-Time PCR Method Targeting a Unique Gene.	Kim E, Yang SM, Kim HY.	Foods	10.3390/foods10092112	2021
	Application of probiotic bacteria in ginsenoside bioconversion and enhancing its health-promoting benefits: a review.	Vasquez R, Song JH, Park YS, Paik HD, Kang DK.	Food Sci Biotechnol	10.1007/s10068-024-01734-6	2025
	Biotransformation of major ginsenosides in ginsenoside model culture by lactic acid bacteria.	Park SE, Na CS, Yoo SA, Seo SH, Son HS.	J Ginseng Res	10.1016/j.jgr.2015.12.008	2017
Pathogenicity	Garvicin A, a novel class IId bacteriocin from Lactococcus garvieae that inhibits septum formation in L. garvieae strains.	Maldonado-Barragan A, Cardenas N, Martinez B, Ruiz-Barba JL, Fernandez-Garayzabal JF, Rodriguez JM, Gibello A.	Appl Environ Microbiol	10.1128/aem.00830-13	2013
	Lactobacillus acidophilus JCM 1132 Strain and Its Mutant with Different Bacteriocin-Producing Behaviour Have Various in Situ Effects on the Gut Microbiota of Healthy Mice.	Wang G, Yu Y, Garcia-Gutierrez E, Jin X, He Y, Wang L, Tian P, Liu Z, Zhao J, Zhang H, Chen W.	Microorganisms	10.3390/microorganisms8010049	2019
Pathogenicity	Determination of cobalamin and related compounds in foods.	Watanabe F, Bito T, Koseki K	Vitam Horm	10.1016/bs.vh.2022.01.009	2022
Enzymology	Optimisation of batch culture conditions for cell-envelope-associated proteinase production from Lactobacillus delbrueckii subsp. lactis ATCC(R) 7830.	Agyei D, Potumarthi R, Danquah MK	Appl Biochem Biotechnol	10.1007/s12010-012-9839-9	2012
Metabolism	Lactobacillus reuteri CRL1098 produces cobalamin.	Taranto MP, Vera JL, Hugenholtz J, De Valdez GF, Sesma F	J Bacteriol	10.1128/JB.185.18.5643-5647.2003	2003
Pathogenicity	Characterization and bioavailability of vitamin B12-compounds from edible algae.	Watanabe F, Takenaka S, Kittaka-Katsura H, Ebara S, Miyamoto E	J Nutr Sci Vitaminol (Tokyo)	10.3177/jnsv.48.325	2002

References

#8617	Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 20355
#20215	Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 )
#34200	; Curators of the CIP;
#66792	Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) .
#67770	Japan Collection of Microorganism (JCM) ; Curators of the JCM;
#68371	Automatically annotated from API 50CH acid .
#68382	Automatically annotated from API zym .
#118881	Collection of Institut Pasteur ; Curators of the CIP; CIP 53.61
#124043	Isabel Schober, Julia Koblitz: Data extracted from sequence databases, automatically matched based on designation and taxonomy .
#125438	Julia Koblitz, Lorenz Christian Reimer, Rüdiger Pukall, Jörg Overmann: Predicting bacterial phenotypic traits through improved machine learning using high-quality, curated datasets. 2024 ( DOI 10.1101/2024.08.12.607695 )
#125439	Philipp Münch, René Mreches, Martin Binder, Hüseyin Anil Gündüz, Xiao-Yin To, Alice McHardy: deepG: Deep Learning for Genome Sequence Data. R package version 0.3.1 .
#126262	A. Lissin, I. Schober, J. F. Witte, H. Lüken, A. Podstawka, J. Koblitz, B. Bunk, P. Dawyndt, P. Vandamme, P. de Vos, J. Overmann, L. C. Reimer: StrainInfo—the central database for linked microbial strain identifiers. ( DOI 10.1093/database/baaf059 )

Rate our new design

Content

About us

Lactobacillus delbrueckii subsp. lactis (DSM 20355, ATCC 7830, NCDO 8118)

Name and taxonomic classification

Morphology

Cell morphology

Culture and growth conditions

Culture medium

Culture temp

Physiology and metabolism

Oxygen tolerance

Spore formation

Murein

Observation

Metabolite utilization

Metabolite tests

Enzymes

API zym

API 50CHac

API biotype100

Isolation, sampling and environmental information

Interaction and safety

Risk assessment

Sequence information

Genome sequences

Genome browser: GCA_001888985

16S sequences

GC content

Genome-based predictions

Predictions

Literature

Literature

References

BacDive

Help

Social Media