Ligilactobacillus agilis (DSM 20509, NCIB 11716, CCUG 31450)

Name: Ligilactobacillus agilis (DSM 20509, NCIB 11716, CCUG 31450)
Creator: BacDive
License: http://creativecommons.org/licenses/by/4.0/

BacDive ID 6407

Type strain

Strain Designation 262

Culture col. no. DSM 20509 NCIB 11716 CCUG 31450 262 NRRL B-14856 10 more

NCBI tax ID(s) 1423718 1601

Special Collections DSMZ CCUG JCM KCTC CIP

History DSMZ <- N. Weiss, 262 JCM <-- DSM 20509 <-- N. Weiss 262. CIP <- 1985, DSMZ <- N. Weiss: strain 262

Links

Ligilactobacillus agilis 262 is an anaerobe bacterium that produces lactate and was isolated from municipal sewage.

lactate production anaerobe genome sequence 16S sequence Bacteria

Name and taxonomic classification

SI-ID 3201

LMG 9186,CCUG 31450,DSM 20509,JCM 1187,NCFB 2744,NCIMB 11716,NCDO 2744,NCIB 11716,CIP 101264,CCRC 12931,CECT 4131,KCTC 3606,NRRL B-14856,BCRC 12931

@ref 20215

Last LPSN update 2026-05-29 08:26:24

Domain Bacteria

Phylum Bacillota

Class Bacilli

Order Lactobacillales

Family Lactobacillaceae

Genus Ligilactobacillus

Species Ligilactobacillus agilis

Full scientific name Ligilactobacillus agilis (Weiss et al. 1982) Zheng et al. 2020

Synonyms (1)

Lactobacillus agilis

BacDive ID	Other strains from **Ligilactobacillus agilis** (8)	Type strain
6406	L. agilis 123, DSM 20508
6408	L. agilis 298, DSM 20510
158984	L. agilis WCA-389-WT-5H1, DSM 102821
160073	L. agilis Cla-CZ-26, DSM 109014
160961	L. agilis JCM 1048, ATCC 43564
160964	L. agilis JCM 1049, KCTC 3158
160967	L. agilis JCM 1050, ATCC 43616
165567	L. agilis JCM 7701

Morphology

Cell morphology

@ref	Gram stain	Confidence
125438	positive	90.167

Culture and growth conditions

Culture medium

@ref	Name	Medium link	Composition
8858	MRS MEDIUM WITH CYSTEINE (DSMZ Medium 232)	Medium recipe at MediaDive	Name: MRS MEDIUM WITH CYSTEINE (DSMZ Medium 232) Composition: Glucose 20.0 g/l Casein peptone 10.0 g/l Meat extract 10.0 g/l Na-acetate 5.0 g/l Yeast extract 5.0 g/l (NH4)2 citrate 2.0 g/l K2HPO4 2.0 g/l Tween 80 1.0 g/l MgSO4 x 7 H2O 0.2 g/l MnSO4 x H2O 0.05 g/l Distilled water
34906	MEDIUM 40- for Lactobacillus and Leuconostoc		Distilled water make up to (1000.000 ml);Man Rogosa Sharp agar (68.000 g)
116161	CIP Medium 40	Medium recipe at CIP

Culture temp

@ref	Growth	Type	Temperature (°C)
8858	positive	growth	37
34906	positive	growth	37
50605	positive	growth	37
67770	positive	growth	37

Physiology and metabolism

Oxygen tolerance

@ref	Oxygen tolerance	Confidence
8858	anaerobe
8858	microaerophile
125439	facultative anaerobe	96.006

Compound production

8858

Compound(L+) lactic acid

Murein

@ref	Murein short key	Type
8858	A31	A1gamma m-Dpm-direct

Metabolite utilization

@ref	Chebi-ID	Metabolite	Utilization activity	Kind of utilization tested
68371	17108 ChEBI	D-arabinose	-	builds acid from	from API 50CH acid
68371	18333 ChEBI	D-arabitol	-	builds acid from	from API 50CH acid
68371	28847 ChEBI	D-fucose	-	builds acid from	from API 50CH acid
68371	62318 ChEBI	D-lyxose	-	builds acid from	from API 50CH acid
68371	17924 ChEBI	D-sorbitol	-	builds acid from	from API 50CH acid
68371	16443 ChEBI	D-tagatose	-	builds acid from	from API 50CH acid
68371	65327 ChEBI	D-xylose	-	builds acid from	from API 50CH acid
68371	17113 ChEBI	erythritol	-	builds acid from	from API 50CH acid
68371	16813 ChEBI	galactitol	-	builds acid from	from API 50CH acid
68371	24265 ChEBI	gluconate	-	builds acid from	from API 50CH acid
68371	17754 ChEBI	glycerol	-	builds acid from	from API 50CH acid
68371	28087 ChEBI	glycogen	-	builds acid from	from API 50CH acid
68371	15443 ChEBI	inulin	-	builds acid from	from API 50CH acid
68371	30849 ChEBI	L-arabinose	-	builds acid from	from API 50CH acid
68371	18403 ChEBI	L-arabitol	-	builds acid from	from API 50CH acid
68371	18287 ChEBI	L-fucose	-	builds acid from	from API 50CH acid
68371	62345 ChEBI	L-rhamnose	-	builds acid from	from API 50CH acid
68371	17266 ChEBI	L-sorbose	-	builds acid from	from API 50CH acid
68371	65328 ChEBI	L-xylose	-	builds acid from	from API 50CH acid
68371	6731 ChEBI	melezitose	-	builds acid from	from API 50CH acid
68371	320061 ChEBI	methyl alpha-D-glucopyranoside	-	builds acid from	from API 50CH acid
68371	43943 ChEBI	methyl alpha-D-mannoside	-	builds acid from	from API 50CH acid
68371	74863 ChEBI	methyl beta-D-xylopyranoside	-	builds acid from	from API 50CH acid
68371	17268 ChEBI	myo-inositol	-	builds acid from	from API 50CH acid
68371	0 ChEBI	Potassium 2-ketogluconate	-	builds acid from	from API 50CH acid
68371	0 ChEBI	Potassium 5-ketogluconate	-	builds acid from	from API 50CH acid
68371	15963 ChEBI	ribitol	-	builds acid from	from API 50CH acid
68371	28017 ChEBI	starch	-	builds acid from	from API 50CH acid
68371	32528 ChEBI	turanose	-	builds acid from	from API 50CH acid
68371	17151 ChEBI	xylitol	-	builds acid from	from API 50CH acid

Pathway annotation

Computationally determined by

@ref	pathway	enzyme coverage	annotated reactions
66794	aspartate and asparagine metabolism	100	9 of 9
66794	formaldehyde oxidation	100	3 of 3
66794	cis-vaccenate biosynthesis	100	2 of 2
66794	palmitate biosynthesis	100	22 of 22
66794	ppGpp biosynthesis	100	4 of 4
66794	coenzyme A metabolism	100	4 of 4
66794	teichoic acid biosynthesis	100	1 of 1
66794	CDP-diacylglycerol biosynthesis	100	2 of 2
66794	acetoin degradation	100	3 of 3
66794	UDP-GlcNAc biosynthesis	100	3 of 3
66794	folate polyglutamylation	100	1 of 1
66794	ceramide biosynthesis	100	1 of 1
66794	anapleurotic synthesis of oxalacetate	100	1 of 1
66794	gluconeogenesis	87.5	7 of 8
66794	C4 and CAM-carbon fixation	87.5	7 of 8
66794	threonine metabolism	80	8 of 10
66794	starch degradation	80	8 of 10
66794	peptidoglycan biosynthesis	80	12 of 15
66794	glycogen metabolism	80	4 of 5
66794	glycogen biosynthesis	75	3 of 4
66794	acetate fermentation	75	3 of 4
66794	pentose phosphate pathway	72.73	8 of 11
66794	cardiolipin biosynthesis	71.43	5 of 7
66794	photosynthesis	71.43	10 of 14
66794	pyrimidine metabolism	71.11	32 of 45
66794	purine metabolism	70.21	66 of 94
66794	valine metabolism	66.67	6 of 9
66794	serine metabolism	66.67	6 of 9
66794	L-lactaldehyde degradation	66.67	2 of 3
66794	cyanate degradation	66.67	2 of 3
66794	glycolysis	64.71	11 of 17
66794	proline metabolism	63.64	7 of 11
66794	phenylalanine metabolism	61.54	8 of 13
66794	NAD metabolism	61.11	11 of 18
66794	methylglyoxal degradation	60	3 of 5
66794	lipoate biosynthesis	60	3 of 5
66794	metabolism of amino sugars and derivatives	60	3 of 5
66794	methionine metabolism	57.69	15 of 26
66794	propanol degradation	57.14	4 of 7
66794	cysteine metabolism	55.56	10 of 18
66794	d-mannose degradation	55.56	5 of 9
66794	CO2 fixation in Crenarchaeota	55.56	5 of 9
66794	non-pathway related	55.26	21 of 38
66794	histidine metabolism	51.72	15 of 29
66794	alanine metabolism	51.72	15 of 29
66794	oxidative phosphorylation	51.65	47 of 91
66794	butanoate fermentation	50	2 of 4
66794	degradation of hexoses	50	9 of 18
66794	ethanol fermentation	50	1 of 2
66794	propionate fermentation	50	5 of 10
66794	glycolate and glyoxylate degradation	50	3 of 6
66794	ketogluconate metabolism	50	4 of 8
66794	cyclohexanol degradation	50	2 of 4
66794	sulfopterin metabolism	50	2 of 4
66794	arginine metabolism	50	12 of 24
66794	isoleucine metabolism	50	4 of 8
66794	isoprenoid biosynthesis	46.15	12 of 26
66794	vitamin B1 metabolism	46.15	6 of 13
66794	metabolism of disaccharids	45.45	5 of 11
66794	glutathione metabolism	42.86	6 of 14
66794	citric acid cycle	42.86	6 of 14
66794	mevalonate metabolism	42.86	3 of 7
66794	lysine metabolism	40.48	17 of 42
66794	vitamin K metabolism	40	2 of 5
66794	3-chlorocatechol degradation	40	2 of 5
66794	Entner Doudoroff pathway	40	4 of 10
66794	arachidonate biosynthesis	40	2 of 5
66794	glycine metabolism	40	4 of 10
66794	glutamate and glutamine metabolism	39.29	11 of 28
66794	urea cycle	38.46	5 of 13
66794	leucine metabolism	38.46	5 of 13
66794	dTDPLrhamnose biosynthesis	37.5	3 of 8
66794	6-hydroxymethyl-dihydropterin diphosphate biosynthesis	37.5	3 of 8
66794	vitamin B6 metabolism	36.36	4 of 11
66794	tetrahydrofolate metabolism	35.71	5 of 14
66794	lipid metabolism	35.48	11 of 31
66794	acetyl CoA biosynthesis	33.33	1 of 3
66794	lipid A biosynthesis	33.33	3 of 9
66794	octane oxidation	33.33	1 of 3
66794	IAA biosynthesis	33.33	1 of 3
66794	degradation of aromatic, nitrogen containing compounds	33.33	4 of 12
66794	sphingosine metabolism	33.33	2 of 6
66794	flavin biosynthesis	33.33	5 of 15
66794	selenocysteine biosynthesis	33.33	2 of 6
66794	degradation of pentoses	32.14	9 of 28
66794	tryptophan metabolism	31.58	12 of 38
66794	myo-inositol biosynthesis	30	3 of 10
66794	ubiquinone biosynthesis	28.57	2 of 7
66794	reductive acetyl coenzyme A pathway	28.57	2 of 7
66794	ascorbate metabolism	27.27	6 of 22
66794	dolichyl-diphosphooligosaccharide biosynthesis	27.27	3 of 11
66794	d-xylose degradation	27.27	3 of 11
66794	degradation of sugar alcohols	25	4 of 16
66794	lactate fermentation	25	1 of 4
66794	toluene degradation	25	1 of 4
66794	carnitine metabolism	25	2 of 8
66794	androgen and estrogen metabolism	25	4 of 16
66794	4-hydroxymandelate degradation	22.22	2 of 9
66794	chorismate metabolism	22.22	2 of 9
66794	polyamine pathway	21.74	5 of 23
66794	tyrosine metabolism	21.43	3 of 14

API 50CHac

@ref	ControlQ	GLY	ERY	DARA	LARA	RIB	DXYL	LXYL	ADO	MDX	GAL	GLU	FRU	MNE	SBE	RHA	DUL	INO	MAN	SOR	MDM	MDG	NAG	AMY	ARB	ESC	SAL	CEL	MAL	LAC	MEL	SAC	TRE	INU	MLZ	RAF	AMD	GLYG	XLT	GEN	TUR	LYX	TAG	DFUC	LFUC	DARL	LARL	GNT	2KG	5KG
8858	-	-	-	-	-	+/-	-	-	-	-	+	+	+	+	-	-	-	-	+	-	-	-	+	+	+	+	+	+	+	+	+	+	+	-	-	+	-	-	-	+	-	-	-	-	-	-	-	-	-	-
116161	not determinedn.d.	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-

Isolation, sampling and environmental information

Isolation source categories

Cat1	Cat2	Cat3
#Engineered	#Waste	#Wastewater

Isolation

@ref	Sample type	Geographic location	Country	Country ISO 3 Code	Continent
8858	municipal sewage
50605	Municipal sewage
67770	Municipal sewage
116161	Environment, Municipal sewage	München	Germany	DEU	Europe

Taxonmaps

69479

Global distribution of 16S sequence LC065041 (>99% sequence identity) for Ligilactobacillus agilis subclade from Microbeatlas

Aquatic Samples	1961
Soil Samples	1642
Animal Samples	36795
Plant Samples	892
Total Samples	41290

Interaction and safety

Risk assessment

@ref	Biosafety level	Biosafety level comment
8858	1	Risk group (German classification) According to TRBA 466
116161	1	Risk group (French classification) According to TRBA 466

Sequence information

Genome sequences

@ref	Description	Assembly level	INSDC accession	BV-BRC accession	IMG accession	NCBI tax ID	Score
67770	ASM143621v1 assembly for Ligilactobacillus agilis DSM 20509	scaffold	GCA_001436215	1423718.3	2667527581	1423718	59.65

16S sequences

@ref	Description	Accession	Length	NCBI tax ID
20218	Lactobacillus agilis strain DSM 20509 16S ribosomal RNA gene, partial sequence	M58803	1511	1601
20218	Lactobacillus agilis gene for 16S rRNA, partial sequence, strain: JCM 1187	AB596945	1485	1601
67770	Lactobacillus agilis gene for 16S ribosomal RNA, partial sequence, strain: JCM 1187	LC065041	1462	1601

GC content

@ref	GC-content (mol%)	Method
8858	43.6
67770	41
67770	41.7	genome sequence analysis

Genome-based predictions

Predictions

Predictions from Deep Learning for Genome Sequence Data. R package version 0.3.1 based on: ASM143621v1 assembly for Ligilactobacillus agilis DSM 20509
NCBI: GCA_001436215

@ref	Trait	Model	Prediction	Confidence in %	In training data
125439	oxygen_tolerance	BacteriaNetⓘ	facultative anaerobe	96.01	no
125439	gram_stain	BacteriaNetⓘ	positive	61.33	no
125439	motility	BacteriaNetⓘ	no	70.50	no
125439	spore_formation	BacteriaNetⓘ	no	78.00	no

Predictions from bacterial phenotypic traits through improved machine learning using high-quality, curated datasets based on: Lactobacillus agilis DSM 20509
PATRIC: 1423718.3

@ref	Trait	Model	Prediction	Confidence in %	In training data
125438	gram-positive	gram-positiveⓘ	yes	90.17	no
125438	anaerobic	anaerobicⓘ	no	81.51	no
125438	spore-forming	spore-formingⓘ	no	79.98	no
125438	aerobic	aerobicⓘ	no	96.20	no
125438	thermophilic	thermophileⓘ	no	96.44	no
125438	flagellated	motile2+ⓘ	yes	56.83	no

Literature

Topic	Title	Authors	Journal	DOI	Year
	Susceptibility of Lactobacillaceae Strains to Aminoglycoside Antibiotics in the Light of EFSA Guidelines.	Dec M, Herman-Ostrzyzek K, Zomer A, Urban-Chmiel R.	Life (Basel)	10.3390/life15050732	2025
	A Controlled, Retrospective, Single-Center Study to Evaluate the Role of a Probiotic Mixture Administered during Pregnancy in Reducing Streptococcus Agalactiae Swab Positivity and the Frequency of Premature Rupture of Amniochorionic Membranes.	Arduini M, Laurenti E, Cazzaniga M, Bertuccioli A, Cavecchia I, Matera M, Zerbinati N, Di Pierro F.	Microorganisms	10.3390/microorganisms12101979	2024
	Investigation of gut microbiota and short-chain fatty acids in Strongyloides stercoralis-infected patients in a rural community.	Nguyen HT, Hongsrichan N, Intuyod K, Pinlaor P, Yingklang M, Chaidee A, Sengthong C, Pongking T, Dangtakot R, Banjong D, Anutrakulchai S, Cha'on U, Pinlaor S.	Biosci Microbiota Food Health	10.12938/bmfh.2021-054	2022
	Temperature-Sensitive Lipids Reveal Intraspecific Diversity in Bacteria Isolated from an Ancient Antarctic Microbial Mat.	Lezcano MA, Carrizo D, Lominchar MA, Sanchez-Garcia L, Quesada A, Parro V.	Microb Ecol	10.1007/s00248-025-02583-4	2025
Metabolism	Inulin Fermentation by Lactobacilli and Bifidobacteria from Dairy Calves.	Zhu Y, Liu J, Lopez JM, Mills DA.	Appl Environ Microbiol	10.1128/aem.01738-20	2020
	Exploiting Potential Probiotic Lactic Acid Bacteria Isolated from Chlorella vulgaris Photobioreactors as Promising Vitamin B12 Producers.	Ribeiro M, Maciel C, Cruz P, Darmancier H, Nogueira T, Costa M, Laranjeira J, Morais RMSC, Teixeira P.	Foods	10.3390/foods12173277	2023
	Baikalomycins A-C, New Aquayamycin-Type Angucyclines Isolated from Lake Baikal Derived Streptomyces sp. IB201691-2A.	Voitsekhovskaia I, Paulus C, Dahlem C, Rebets Y, Nadmid S, Zapp J, Axenov-Gribanov D, Ruckert C, Timofeyev M, Kalinowski J, Kiemer AK, Luzhetskyy A.	Microorganisms	10.3390/microorganisms8050680	2020
	HPV infection alters vaginal microbiome through down-regulating host mucosal innate peptides used by Lactobacilli as amino acid sources.	Lebeau A, Bruyere D, Roncarati P, Peixoto P, Hervouet E, Cobraiville G, Taminiau B, Masson M, Gallego C, Mazzucchelli G, Smargiasso N, Fleron M, Baiwir D, Hendrick E, Pilard C, Lerho T, Reynders C, Ancion M, Greimers R, Twizere JC, Daube G, Schlecht-Louf G, Bachelerie F, Combes JD, Melin P, Fillet M, Delvenne P, Hubert P, Herfs M.	Nat Commun	10.1038/s41467-022-28724-8	2022
Pathogenicity	d-Alanyl-d-Alanine Ligase as a Broad-Host-Range Counterselection Marker in Vancomycin-Resistant Lactic Acid Bacteria.	Zhang S, Oh JH, Alexander LM, Ozcam M, van Pijkeren JP.	J Bacteriol	10.1128/jb.00607-17	2018
Pathogenicity	Directing Drugs to Bugs: Antibiotic-Carbohydrate Conjugates Targeting Biofilm-Associated Lectins of Pseudomonas aeruginosa.	Meiers J, Zahorska E, Rohrig T, Hauck D, Wagner S, Titz A.	J Med Chem	10.1021/acs.jmedchem.0c00856	2020
Metabolism	Characterization and identification of Pediococcus species isolated from forage crops and their application for silage preparation.	Cai Y, Kumai S, Ogawa M, Benno Y, Nakase T.	Appl Environ Microbiol	10.1128/aem.65.7.2901-2906.1999	1999
	Identification, molecular diversity, phylogenetic analysis, and antimicrobial activity of lactobacilli isolated from buffalo raw milk	Zolfaghari SI, Amin M.	Int Dairy J		2025
Genetics	Complete genome sequence of Ligilactobacillus agilis LDTM47, bacteriocin-producing lactic acid bacteria isolated from broiler gastrointestinal tract.	Eum BG, Elnar AG, Jang Y, Kim GB.	J Anim Sci Technol	10.5187/jast.2024.e29	2025
	Evaluation of the techno-functional properties of lactobacilli strains originated from Bos indicus and Bubalus bubalis calves for probiotic potential.	Kumar S, Chauhan N, Chauhan T, Balaga S, Tyagi N, Samanta AK.	Int Microbiol	10.1007/s10123-025-00641-y	2025
	Harnessing flagellin of Ligilactobacillus agilis as a surface display scaffold for an HIV-1 epitope.	Suzuki S, Dean GA, Kajikawa A.	Appl Environ Microbiol	10.1128/aem.00674-25	2025
Genetics	Whole-Genome Sequence Analysis and Subtractive Screening of Lactobacilli in the Searching for New Probiotics to Protect the Mammary Glands.	Bujnakova D, Galambosiova T, Karahutova L.	Int J Mol Sci	10.3390/ijms262110809	2025
	Isolation and molecular identification of Lactobacillaceae bacteria and Bifidobacterium from horse feces.	Fujimoto R, Kuchida M, Ban-Tokuda T, Matsui H.	J Equine Sci	10.1294/jes.36.39	2025
Genetics	Characterization and functionality of Ligilactobacillus agilis 1003 isolated from chicken cecum against Klebsiella pneumoniae.	Yin HC, Jiang DH, Yu TF, Jiang XJ, Liu D.	Front Cell Infect Microbiol	10.3389/fcimb.2024.1432422	2024
	Gut Microbiota Composition Correlates to Trunk Fat Percentage in Male Cynomolgus Macaque Monkeys.	Lutzhoft DO, Jacobsen RR, Stefanova DV, Pedersen KM, Nielsen DS, Christoffersen BO, Bader L, Kirigiti M, Straarup EM, Kievit P, Hansen AK.	Clin Transl Sci	10.1111/cts.70393	2025
	Probiotic characterization of indigenous lactic acid bacteria isolates from chickens to be used as biocontrol agents in poultry industry	Moretti AF, Gamba R, De Antoni G, Pelaez AL, Golowczyc MA.	Journal of food processing and preservation.		2022
Metabolism	Ligilactobacillus agilis BKN88 possesses thermo-/acid-stable heteropolymeric flagellar filaments.	Eguchi N, Suzuki S, Yokota K, Igimi S, Kajikawa A.	Microbiology (Reading)	10.1099/mic.0.001020	2021
	Characterization of Novel Amylase-Sensitive, Anti-Listerial Class IId Bacteriocin, Agilicin C7 Produced by Ligilactobacillus agilis C7.	Yoo JM, Song JH, Vasquez R, Hwang IC, Lee JS, Kang DK.	Food Sci Anim Resour	10.5851/kosfa.2023.e24	2023
	Screening of Lactic Acid Bacterial Strains with Antiviral Activity Against Porcine Epidemic Diarrhea.	Chen YM, Limaye A, Chang HW, Liu JR.	Probiotics Antimicrob Proteins	10.1007/s12602-021-09829-w	2022
	Iron Fortification and Inulin Supplementation in Early Infancy: Evaluating the Impact on Gut Microbiome in a Piglet Model.	Park J, Jinno C, Wickramasinghe S, Mills DA, Liu Y, Lonnerdal BL, Ji P.	Curr Dev Nutr	10.1016/j.cdnut.2025.104587	2025
	Negative chemotaxis of Ligilactobacillus agilis BKN88 against gut-derived substances.	Suzuki S, Yokota K, Igimi S, Kajikawa A.	Sci Rep	10.1038/s41598-023-42840-5	2023
	Antioxidant, Anti-Inflammatory, Antagonistic, and Probiotic Properties of Lactic Acid Bacteria Isolated from Traditional Algerian Fermented Wheat	Benguiar R, Benaraba R, Farhat C, Chouchane H, Boughaddou D, Belalem F, Cherif A.	Microorganisms		2025
	Impact of a defined bacterial community including and excluding Megamonas hypermegale on broiler cecal microbiota and resistance to Salmonella infection.	Schultz Marcolla C, Ju T, Ten K, Sivakumar Sharma U, Moeun L, Willing BP.	Appl Environ Microbiol	10.1128/aem.00948-25	2025
Pathogenicity	Immunogenic Modification of Ligilactobacillus agilis by Specific Amino Acid Substitution of Flagellin.	Kajikawa A, Eguchi N, Suzuki S.	Appl Environ Microbiol	10.1128/aem.01277-22	2022
	Lactobacillus salivarius CML352 Isolated from Chinese Local Breed Chicken Modulates the Gut Microbiota and Improves Intestinal Health and Egg Quality in Late-Phase Laying Hens.	Xu C, Wei F, Yang X, Feng Y, Liu D, Hu Y.	Microorganisms	10.3390/microorganisms10040726	2022
	Age-driven changes in the layer hen reproductive microbiome are associated with lay performance.	Ellwood KM, Kramer AE, Dutta A.	Poult Sci	10.1016/j.psj.2025.105703	2025
Genetics	Uncovering encrypted antimicrobial peptides in health-associated Lactobacillaceae by large-scale genomics and machine learning.	Du R, Han F, Li Z, Yu J, Xu Y, Huang Y, Wu Q.	Microbiome	10.1186/s40168-025-02145-3	2025
	Iron Fortification and Inulin Supplementation in Early Infancy: Evaluating the Impact on Iron Metabolism and Trace Mineral Status in a Piglet Model.	Park J, Wickramasinghe S, Mills DA, Lonnerdal BL, Ji P.	Curr Dev Nutr	10.1016/j.cdnut.2024.102147	2024
	Probiotic potential of autochthonous Lactobacillus species from buffalo calves in controlling multidrug resistant Escherichia coli.	Moturi S, Kommalapati LK, Metta M, Chappidi VS, Jatavathu S.	Vet Res Forum	10.30466/vrf.2024.2012559.4024	2024
	In Vitro and In Vivo Evaluation of Bacillus Strains as Prophylactic Agents Against Porcine Epidemic Diarrhea Virus.	Chen YJ, Tsai CF, Hsu CW, Chang HW, Liu JR.	Animals (Basel)	10.3390/ani15040470	2025
	Associations between intestinal lactic acid bacteria species and feeding habits of zoo animals.	Horie M, Ohno T, Iwahashi H, Umemura M, Murotomi K.	Microbiome Res Rep	10.20517/mrr.2024.08	2024
	Multi-functional properties of lactic acid bacteria strains derived from canine feces.	Liu Y, Wang J, Zheng H, Xin J, Zhong Z, Liu H, Fu H, Zhou Z, Qiu X, Peng G.	Front Vet Sci	10.3389/fvets.2024.1404580	2024
	Carbohydrate-active enzyme profiles of Lactiplantibacillus plantarum strain 84-3 contribute to flavor formation in fermented dairy and vegetable products.	Liang T, Jiang T, Liang Z, Zhang N, Dong B, Wu Q, Gu B.	Food Chem X	10.1016/j.fochx.2023.101036	2023
Genetics	Functional Insights Into the Effect of Feralisation on the Gut Microbiota of Cats Worldwide.	Aizpurua O, Botnen AB, Eisenhofer R, Odriozola I, Santos-Bay L, Bjornsen MB, Gilbert MTP, Alberdi A.	Mol Ecol	10.1111/mec.17695	2025
	Evaluation of Quality of Nitrite-Free Fermented Roe Deer (Capreolus capreolus) Sausage with Addition of Ascorbic Acid and Reduced NaCl.	Wojciak KM, Keska P, Kacaniova M, Cmikova N, Solska E, Ogorek A.	Foods	10.3390/foods13233823	2024
Genetics	16S-rRNA-Based Metagenomic Profiling of the Bacterial Communities in Traditional Bulgarian Sourdoughs.	Baev V, Apostolova E, Gotcheva V, Koprinarova M, Papageorgiou M, Rocha JM, Yahubyan G, Angelov A.	Microorganisms	10.3390/microorganisms11030803	2023
Phylogeny	Understanding Age-Related Longitudinal Dynamics in Abundance and Diversity of Dominant Culturable Gut Lactic Acid Bacteria in Pastured Goats.	ElHadedy DE, Kim C, Yousuf AB, Wang Z, Ndegwa EN.	Animals (Basel)	10.3390/ani13162669	2023
Genetics	Stable Recombinant-Gene Expression from a Ligilactobacillus Live Bacterial Vector via Chromosomal Integration.	Vezina B, Allnutt T, Keyburn AL, Wade B, Van TTH, Johanesen P, Lyras D, Moore RJ.	Appl Environ Microbiol	10.1128/aem.00392-21	2021
	Effects of Neolamarckia cadamba leaves extract on microbial community and antibiotic resistance genes in cecal contents and feces of broilers challenged with lipopolysaccharides.	Wang C, Wu S, Zhou W, Hu L, Hu Q, Cao Y, Wang L, Chen X, Zhang Q.	Appl Environ Microbiol	10.1128/aem.01107-23	2024
	Dual Inhibition of Salmonella enterica and Clostridium perfringens by New Probiotic Candidates Isolated from Chicken Intestinal Mucosa.	Lone A, Mottawea W, Ait Chait Y, Hammami R.	Microorganisms	10.3390/microorganisms9010166	2021
	Enterococcus faecalis Is a Better Competitor Than Other Lactic Acid Bacteria in the Initial Colonization of Colon of Healthy Newborn Babies at First Week of Their Life.	Al-Balawi M, Morsy FM.	Front Microbiol	10.3389/fmicb.2020.02017	2020
	Genomic and transcriptomic analysis of Ligilactobacillus salivarius IBB3154-in search of new promoters for vaccine construction.	Kobierecka P, Wyszynska A, Aleksandrzak-Piekarczyk T, Salanska A, Gawor J, Bardowski J, Jagusztyn Krynicka KE.	Microbiol Spectr	10.1128/spectrum.02844-23	2023
Genetics	Host specific adaptations of Ligilactobacillus aviarius to poultry.	Rios Galicia B, Saenz JS, Yergaliyev T, Camarinha-Silva A, Seifert J.	Curr Res Microb Sci	10.1016/j.crmicr.2023.100199	2023
Genetics	Characterization of Ligilactobacillus salivarius CRISPR-Cas systems.	Roberts A, Spang D, Sanozky-Dawes R, Nethery MA, Barrangou R.	mSphere	10.1128/msphere.00171-24	2024
	Fine-tuning of post-weaning pig microbiome structure and functionality by in-feed zinc oxide and antibiotics use.	Ortiz Sanjuan JM, Manzanilla EG, Cabrera-Rubio R, Crispie F, Cotter PD, Garrido JJ, Ekhlas D, O'Neill L, Arguello H.	Front Cell Infect Microbiol	10.3389/fcimb.2024.1354449	2024
	The active core microbiota of two high-yielding laying hen breeds fed with different levels of calcium and phosphorus.	Roth C, Sims T, Rodehutscord M, Seifert J, Camarinha-Silva A.	Front Physiol	10.3389/fphys.2022.951350	2022
	Evaluating the effects of dietary glutamine on performance, carcass traits, blood biochemistry, and intestine morphology in laying quail.	Tomaszewska E, Drabik K, Kasperek K, Dobrowolski P, Hulas-Stasiak M, Pyz-Lukasik R, Paszkiewicz W, Ziomek M, Donaldson J, Dobrowolska K, Burmaczuk A, Batkowska J, Arciszewski MB, Muszynski S.	Poult Sci	10.1016/j.psj.2025.104879	2025
	Gene Rearrangement and Modification of Immunity Factors Are Correlated with the Insertion of Bacteriocin Cassettes in Streptococcus mutans.	Le MN, Kawada-Matsuo M, Komatsuzawa H.	Microbiol Spectr	10.1128/spectrum.01806-21	2022
	Donor-dependent fecal microbiota transplantation efficacy against necrotizing enterocolitis in preterm pigs.	Hui Y, Vestergaard G, Deng L, Kot WP, Thymann T, Brunse A, Nielsen DS.	NPJ Biofilms Microbiomes	10.1038/s41522-022-00310-2	2022
	Cell-surface protein YwfG of Lactococcus lactis binds to alpha-1,2-linked mannose.	Tsuchiya W, Fujimoto Z, Inagaki N, Nakagawa H, Tanaka M, Kimoto-Nira H, Yamazaki T, Suzuki C.	PLoS One	10.1371/journal.pone.0273955	2023
Genetics	Longitudinal study on the effects of growth-promoting and therapeutic antibiotics on the dynamics of chicken cloacal and litter microbiomes and resistomes.	Gupta CL, Blum SE, Kattusamy K, Daniel T, Druyan S, Shapira R, Krifucks O, Zhu YG, Zhou XY, Su JQ, Cytryn E.	Microbiome	10.1186/s40168-021-01136-4	2021
	Ligilactobacillus ubinensis sp. nov., a novel species isolated from the wild ferment of a durian fruit (Durio zibethinus).	Heng YC, Menon N, Chen B, Loo BZL, Wong GWJ, Lim ACH, Silvaraju S, Kittelmann S.	Int J Syst Evol Microbiol	10.1099/ijsem.0.005733	2023
	Arthrobacter crusticola sp. nov., Isolated from Biological Soil Crusts in the Mu Us Sandy Land, China.	Liu L, Liang L, He S, Xu L, Chi M, Shi S, Zhang X, Li L.	Curr Microbiol	10.1007/s00284-020-02070-8	2020
Phylogeny	Arthrobacter ruber sp. nov., isolated from glacier ice.	Liu Q, Xin YH, Chen XL, Liu HC, Zhou YG, Chen WX.	Int J Syst Evol Microbiol	10.1099/ijsem.0.002719	2018
Phylogeny	Arthrobacter pityocampae sp. nov., isolated from Thaumetopoea pityocampa (Lep., Thaumetopoeidae).	Ince IA, Demirbag Z, Kati H.	Int J Syst Evol Microbiol	10.1099/ijs.0.060731-0	2014
Phylogeny	Dermacoccus abyssi sp. nov., a piezotolerant actinomycete isolated from the Mariana Trench.	Pathom-Aree W, Nogi Y, Sutcliffe IC, Ward AC, Horikoshi K, Bull AT, Goodfellow M.	Int J Syst Evol Microbiol	10.1099/ijs.0.64133-0	2006

References

#8858	Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 20509
#20215	Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 )
#20218	Verslyppe, B., De Smet, W., De Baets, B., De Vos, P., Dawyndt P.: StrainInfo introduces electronic passports for microorganisms.. Syst Appl Microbiol. 37: 42 - 50 2014 ( DOI 10.1016/j.syapm.2013.11.002 , PubMed 24321274 )
#34906	; Curators of the CIP;
#50605	Culture Collection University of Gothenburg (CCUG) ; Curators of the CCUG; CCUG 31450
#66794	Antje Chang, Lisa Jeske, Sandra Ulbrich, Julia Hofmann, Julia Koblitz, Ida Schomburg, Meina Neumann-Schaal, Dieter Jahn, Dietmar Schomburg: BRENDA, the ELIXIR core data resource in 2021: new developments and updates. Nucleic Acids Res. 49: D498 - D508 2020 ( DOI 10.1093/nar/gkaa1025 , PubMed 33211880 )
#67770	Japan Collection of Microorganism (JCM) ; Curators of the JCM;
#68371	Automatically annotated from API 50CH acid .
#69479	João F Matias Rodrigues, Janko Tackmann,Gregor Rot, Thomas SB Schmidt, Lukas Malfertheiner, Mihai Danaila,Marija Dmitrijeva, Daniela Gaio, Nicolas Näpflin and Christian von Mering. University of Zurich.: MicrobeAtlas 1.0 beta .
#116161	Collection of Institut Pasteur ; Curators of the CIP; CIP 101264
#125438	Julia Koblitz, Lorenz Christian Reimer, Rüdiger Pukall, Jörg Overmann: Predicting bacterial phenotypic traits through improved machine learning using high-quality, curated datasets. 2024 ( DOI 10.1101/2024.08.12.607695 )
#125439	Philipp Münch, René Mreches, Martin Binder, Hüseyin Anil Gündüz, Xiao-Yin To, Alice McHardy: deepG: Deep Learning for Genome Sequence Data. R package version 0.3.1 .
#126262	A. Lissin, I. Schober, J. F. Witte, H. Lüken, A. Podstawka, J. Koblitz, B. Bunk, P. Dawyndt, P. Vandamme, P. de Vos, J. Overmann, L. C. Reimer: StrainInfo—the central database for linked microbial strain identifiers. ( DOI 10.1093/database/baaf059 )

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Ligilactobacillus agilis (DSM 20509, NCIB 11716, CCUG 31450)

Name and taxonomic classification

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