Name: Lactobacillus acidophilus L917
Creator: BacDive
License: http://creativecommons.org/licenses/by-nc/4.0/

Strain identifier

BacDive ID: 6404

Type strain:

Species: Lactobacillus acidophilus

Strain Designation: L917, Scav

Culture col. no.: DSM 20079, ATCC 4356, NCDO 1748, NCIB 8690, WDCM 00098, CCUG 5917, IFO 13951, CCM 4833, JCM 1132, BCRC 10695, CECT 903, CGMCC 1.1878, CIP 76.13, HAMBI 84, KCTC 3111, KCTC 3164, LMG 13550, LMG 9433, NBRC 13951, NCCB 98067, NCFB 1748, NCIMB 8690, NCTC 12980, NRIC 1547, NRRL B-23431, NRRL B-4239, NRRL B-4495, VKM B-1660, VPI 6032, VTT E-96276

Strain history: ATCC 4356 <-- W. L. Kulp strain Scav (P. A. Hansen L917).

NCBI tax ID(s): 1423717 (strain), 1579 (species)

Other strains from Lactobacillus acidophilus

Section

Lactobacillus acidophilus L917 is an anaerobe, mesophilic human pathogen that produces lactate and was isolated from human.

lactate production
anaerobe
human pathogen
mesophilic
16S sequence
Bacteria
genome sequence

Information on the name and the taxonomic classification. Name and taxonomic classification

	Last LPSN update	07-12-2022 (DD-MM-YYYY)
	Domain	"Bacteria"
	Phylum	*Bacillota*
	Class	*Bacilli*
	Order	*Lactobacillales*
	Family	*Lactobacillaceae*
	Genus	*Lactobacillus*
	Species	**Lactobacillus acidophilus**
	Full Scientific Name (PNU)	Lactobacillus acidophilus (Moro 1900) Hansen and Mocquot 1970 (Approved Lists 1980)

Synonym

"Bacillus acidophilus"

Information on culture and growth conditions Culture and growth conditions

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Culture medium

MRS MEDIUM WITH CYSTEINE (DSMZ Medium 232)

[Ref.: #8506]

Culture medium growth

[Ref.: #8506]

Culture medium link

Medium recipe provided by DSMZ

[Ref.: #8506]

Culture medium composition

expand / minimize

[Ref.: #41980]

Culture medium

MEDIUM 40- for Lactobacillus and Leuconostoc

[Ref.: #41980]

Culture medium growth

[Ref.: #41980]

Culture medium composition

expand / minimize

		Temperature
[Ref.: #8506]	growth	37 °C
[Ref.: #41980]	growth	30 °C
[Ref.: #44877]	growth	30 °C
[Ref.: #44877]	growth	37 °C
[Ref.: #67770]	growth	37 °C

[Ref.: #8506]	Temperature range	mesophilic
[Ref.: #41980]	Temperature range	mesophilic
[Ref.: #44877]	Temperature range	mesophilic
[Ref.: #67770]	Temperature range	mesophilic

Information on physiology and metabolism Physiology and metabolism

[Ref.: #8506]

Oxygen tolerance

anaerobe

[Ref.: #8506]	Name of produced compound	DL lactic acid
[Ref.: #67770]	Name of produced compound	Acidocin J1132

[Ref.: #8506]	Murein short key	A11.31
[Ref.: #8506]	Murein types	A4alpha L-Lys-D-Asp

	Metabolite	Utilization activity	Kind of utilization tested
[Ref.: #68371]	amygdalin ChEBI	+	builds acid from	* from API 50CH acid
[Ref.: #68371]	arbutin ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #22927]	cellobiose ChEBI	+	growth
[Ref.: #68371]	cellobiose ChEBI	+	builds acid from	* from API 50CH acid
[Ref.: #68371]	D-arabinose ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	D-arabitol ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	D-fructose ChEBI	+	builds acid from	* from API 50CH acid
[Ref.: #68371]	D-fucose ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	D-galactose ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	D-glucose ChEBI	+	builds acid from	* from API 50CH acid
[Ref.: #68371]	D-lyxose ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	D-mannitol ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68379]	D-mannitol ChEBI	-	fermentation	* from API Coryne
[Ref.: #68371]	D-mannose ChEBI	+	builds acid from	* from API 50CH acid
[Ref.: #68371]	D-ribose ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68379]	D-ribose ChEBI	-	fermentation	* from API Coryne
[Ref.: #68371]	D-sorbitol ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	D-tagatose ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	D-xylose ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68379]	D-xylose ChEBI	-	fermentation	* from API Coryne
[Ref.: #22928]	erythritol ChEBI	-	growth
[Ref.: #68371]	erythritol ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	esculin ChEBI	+	builds acid from	* from API 50CH acid
[Ref.: #68379]	esculin ChEBI	+	hydrolysis	* from API Coryne
[Ref.: #68371]	galactitol ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #22927]	galactose ChEBI	+/-	growth
[Ref.: #68379]	gelatin ChEBI	-	hydrolysis	* from API Coryne
[Ref.: #22927]	gentiobiose ChEBI	+	growth
[Ref.: #68371]	gentiobiose ChEBI	+	builds acid from	* from API 50CH acid
[Ref.: #68371]	gluconate ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	glycerol ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #22927]	glycogen ChEBI	-	growth
[Ref.: #22928]	glycogen ChEBI	+	growth
[Ref.: #68371]	glycogen ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68379]	glycogen ChEBI	-	fermentation	* from API Coryne
[Ref.: #68371]	inulin ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	L-arabinose ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	L-arabitol ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	L-fucose ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	L-rhamnose ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	L-sorbose ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	L-xylose ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	lactose ChEBI	+	builds acid from	* from API 50CH acid
[Ref.: #68379]	lactose ChEBI	-	fermentation	* from API Coryne
[Ref.: #68371]	maltose ChEBI	+	builds acid from	* from API 50CH acid
[Ref.: #68379]	maltose ChEBI	+	fermentation	* from API Coryne
[Ref.: #22928]	mannitol ChEBI	-	growth
[Ref.: #22928]	mannose ChEBI	+	growth
[Ref.: #68371]	melezitose ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	melibiose ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	methyl alpha-D-glucopyranoside ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	methyl alpha-D-mannoside ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	methyl beta-D-xylopyranoside ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	myo-inositol ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	N-acetylglucosamine ChEBI	+	builds acid from	* from API 50CH acid
[Ref.: #68379]	nitrate ChEBI	-	reduction	* from API Coryne
[Ref.: #68371]	Potassium 2-ketogluconate	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	Potassium 5-ketogluconate	-	builds acid from	* from API 50CH acid
[Ref.: #22927]	raffinose ChEBI	+/-	growth
[Ref.: #68371]	raffinose ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	ribitol ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68371]	salicin ChEBI	+	builds acid from	* from API 50CH acid
[Ref.: #22928]	sorbitol ChEBI	-	growth
[Ref.: #22927]	starch ChEBI	+/-	growth
[Ref.: #68371]	starch ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #22928]	sucrose ChEBI	+	growth
[Ref.: #68371]	sucrose ChEBI	+	builds acid from	* from API 50CH acid
[Ref.: #68379]	sucrose ChEBI	+	fermentation	* from API Coryne
[Ref.: #22927]	trehalose ChEBI	+/-	growth
[Ref.: #68371]	trehalose ChEBI	+	builds acid from	* from API 50CH acid
[Ref.: #68371]	turanose ChEBI	-	builds acid from	* from API 50CH acid
[Ref.: #68379]	urea ChEBI	-	hydrolysis	* from API Coryne
[Ref.: #68371]	xylitol ChEBI	-	builds acid from	* from API 50CH acid
	Only first 10 entries are displayed. Click here to see all.

	Antibiotica	Metabolite
[Ref.: #22928]		penicillin g ChEBI

	Enzyme	Enzyme activity	EC number
[Ref.: #68379]	alkaline phosphatase	-	3.1.3.1	* from API Coryne
[Ref.: #68379]	alpha-glucosidase	-	3.2.1.20	* from API Coryne
[Ref.: #68379]	beta-galactosidase	+	3.2.1.23	* from API Coryne
[Ref.: #68379]	beta-glucosidase	+	3.2.1.21	* from API Coryne
[Ref.: #68379]	beta-glucuronidase	-	3.2.1.31	* from API Coryne
[Ref.: #68379]	catalase	-	1.11.1.6	* from API Coryne
[Ref.: #68379]	gelatinase	-		* from API Coryne
[Ref.: #68379]	N-acetyl-beta-glucosaminidase	-	3.2.1.52	* from API Coryne
[Ref.: #68379]	pyrazinamidase	+	3.5.1.B15	* from API Coryne
[Ref.: #68379]	pyrrolidonyl arylamidase	-	3.4.19.3	* from API Coryne
[Ref.: #68379]	urease	-	3.5.1.5	* from API Coryne
	Only first 10 entries are displayed. Click here to see all.

Fatty acid profile

Metadata FA analysis

Reference

[Ref.: #44877]

Fatty acid	Percentage	ECL
C18:2 ω6,9c/C18:0 ANTE	33.8	17.724
C18:1 ω9c	31.3	17.769
C16:0	16.9	16
C18:0	8.3	18
C14:0	3.6	14
C16:1 ω7c	3.3	15.819
C19:0 CYCLO ω9c	2.8	18.87

API® 50CH acid:

Note that the displayed test results represent raw data and therefore may deviate!

	API ID	ControlQ	Acid from glycerolGLY	Acid from erythritolERY	Acid from D-arabinoseDARA	Acid from L-arabinoseLARA	Acid from D-riboseRIB	Acid from D-xyloseDXYL	Acid from L-xyloseLXYL	Acid from D-adonitolADO	Acid from methyl beta-D-xylopyranosideMDX	Acid from D-galactoseGAL	Acid from D-glucoseGLU	Acid from D-fructoseFRU	Acid from D-mannoseMNE	Acid from L-sorboseSBE	Acid from L-rhamnoseRHA	Acid from dulcitolDUL	Acid from inositolINO	Acid from D-mannitolMAN	Acid from D-sorbitolSOR	Acid from methyl alpha-D-mannopyranosideMDM	Acid from methyl alpha-D-glucopyranosideMDG	Acid from N-acetyl-glucosamineNAG	Acid from amygdalinAMY	Acid from arbutinARB	Acid from esculinESC	Acid from salicinSAL	Acid from cellobioseCEL	Acid from maltoseMAL	Acid from lactoseLAC	Acid from melibioseMEL	Acid from sucroseSAC	Acid from trehaloseTRE	Acid from inulinINU	Acid from melezitoseMLZ	Acid from raffinoseRAF	Acid from starchAMD	Acid from glycogenGLYG	Acid from xylitolXLT	Acid from gentiobioseGEN	Acid from turanoseTUR	Acid from D-lyxoseLYX	Acid from D-tagatoseTAG	Acid from D-fucoseDFUC	Acid from L-fucoseLFUC	Acid from D-arabitolDARL	Acid from L-arabitolLARL	Acid from gluconateGNT	Acid from 2-Ketogluconate2KG	Acid from 5-Ketogluconate5KG
[Ref.: #8506]	8569	-	-	-	-	-	-	-	-	-	-	-	+	+	+	-	-	-	-	-	-	-	-	+	+	-	+	+	+	+	+	-	+	+	-	-	-	-	-	-	+	-	-	-	-	-	-	-	-	-	-
[Ref.: #8506]	8150	-	-	-	-	-	-	-	-	-	-	-	+	+	+	-	-	-	-	-	-	-	-	+	+	-	+	+	+	+	+	-	+	+	-	-	-	-	-	-	+	-	-	-	-	-	-	-	-	-	-
[Ref.: #8506]	8149	-	-	-	-	-	-	-	-	-	-	-	+	+	+	-	-	-	-	-	-	-	-	+	+	-	+	+	+	+	+	-	+	+	-	-	-	-	-	-	+	-	-	-	-	-	-	-	-	-	-
[Ref.: #8506]	8148	-	-	-	-	-	-	-	-	-	-	-	+	+	+	-	-	-	-	-	-	-	-	+	+	-	+	+	+	+	+	-	+	+	-	-	-	-	-	-	+	-	-	-	-	-	-	-	-	-	-
[Ref.: #8506]	8147	-	-	-	-	-	-	-	-	-	-	-	+	+	+	-	-	-	-	-	-	-	-	+	+	-	+	+	+	+	+	-	+	+	-	-	-	-	-	-	+	-	-	-	-	-	-	-	-	-	-

API® Coryne:

Note that the displayed test results represent raw data and therefore may deviate!

	API ID	Reduction of nitrateNIT	PyrazinamidasePYZ	Pyrrolidonyl arylamidasePYRA	Alkaline phosphatasePAL	beta-Glucuronidasebeta GUR	beta-Galactosidasebeta GAL	alpha-Glucosidasealpha GLU	N-Acetyl-beta-Glucosidasebeta NAG	Esculin hydrolysis/beta-GlucosidaseESC	Urease/urea hydrolysisURE	Gelatinase/gelatin hydrolysisGEL	Control fermentationControl	Fermentation of D-glucoseGLU	Fermentation of D-riboseRIB	Fermentation of D-xyloseXYL	Fermentation of D-mannitolMAN	Fermentation of maltoseMAL	Fermentation of lactoseLAC	Fermentation of sucroseSAC	Fermentation of glycogenGLYG	CatalaseCAT
[Ref.: #44877]	1779	-	+	-	-	-	+	-	-	+	-	-	-	not determinedn.d.	-	-	-	+	-	+	-	-

Information on isolation source, the sampling and environmental conditions Isolation, sampling and environmental information

[Ref.: #8506]	Sample type/isolated from	human

[Ref.: #44877]	Sample type/isolated from	Human

[Ref.: #67770]	Sample type/isolated from	Human feces
* marker position based on {}

Isolation sources categories

#Host

#Human

What are isolation sources categories?

[Ref.: #69479]

Global distribution of 16S sequence LC064893 (>99% sequence identity) for Lactobacillus acidophilus from Microbeatlas

Aquatic Samples	1233
Soil Samples	892
Animal Samples	37635
Plant Samples	522
Total Samples	40282

Information on possible application of the strain and its possible interaction with e.g. potential hosts Safety information

[Ref.: #8506]	Pathogenicity (human)	yes, in single cases
[Ref.: #8506]	Biosafety level	1	Risk group (German classification) According to TRBA 466

Information on genomic background e.g. entries in nucleic sequence databass Sequence information

16S Sequence information:

Only first 5 entries are displayed. Click here to see all.

	Sequence accession description	Seq. accession number	Sequence length (bp)	Sequence database	Associated NCBI tax ID
[Ref.: #20218]	Lactobacillus acidophilus gene for 16S rRNA, partial sequence, strain: YIT 0070 (= ATCC 4356)	AB008203	1553	ENA	1579 tax ID	*
[Ref.: #20218]	Lactobacillus acidophilus genes for 16S rRNA, 16S-23S intergenic spacer region, 23S rRNA, partial and complete sequence, strain:ATCC 4356	AB092634	709	ENA	1579 tax ID	*
[Ref.: #20218]	Lactobacillus acidophilus ATCC 4356 16S ribosomal RNA gene, partial sequence	AF429493	504	ENA	1579 tax ID	*
[Ref.: #20218]	Lactobacillus acidophilus strain ATCC 4356 16S ribosomal RNA gene, partial sequence; 16S-23S intergenic spacer, complete sequence; and 23S ribosomal RNA gene, partial sequence	AF429580	519	ENA	1579 tax ID	*
[Ref.: #20218]	Lactobacillus acidophilus 16S ribosomal RNA	M58802	1569	ENA	1579 tax ID	*
[Ref.: #20218]	Lactobacillus acidophilus 16S-23S rRNA spacer region	U32971	206	ENA	1579 tax ID	*
[Ref.: #20218]	L.acidophilus rrn operon, 16S-23S rRNA spacer (short)	Z75472	204	ENA	1579 tax ID	*
[Ref.: #20218]	L.acidophilus rrn operon, 16S-23S rRNA spacer (long), tRNA-Ile and tRNA-Ala genes	Z75473	451	ENA	1579 tax ID	*
[Ref.: #20218]	Lactobacillus acidophilus strain BCRC10695 16S ribosomal RNA gene, complete sequence	AY773947	1478	ENA	1579 tax ID	*
[Ref.: #20218]	Lactobacillus acidophilus partial 16S rRNA gene, strain VPI 6032	FR683087	1531	ENA	1579 tax ID	*
[Ref.: #20218]	Lactobacillus acidophilus strain DSM 20079 16S ribosomal RNA gene, partial sequence	EF468098	262	ENA	1579 tax ID	*
[Ref.: #20218]	Lactobacillus acidophilus strain DSM 20079 16S ribosomal RNA gene, partial sequence	HQ012028	936	ENA	1579 tax ID	*
[Ref.: #20218]	Lactobacillus acidophilus gene for 16S rRNA, partial sequence, strain: JCM 1132	AB289017	688	ENA	1579 tax ID	*
[Ref.: #20218]	Lactobacillus acidophilus 16S ribosomal RNA, partial sequence; 16S/23S intergenic spacer region, complete sequence; and 23S ribosomal RNA partial sequence	AF182726	661	ENA	1579 tax ID	*
[Ref.: #20218]	Lactobacillus acidophilus gene for 16S rRNA, partial sequence, strain: NBRC 13951	AB680529	1489	ENA	1579 tax ID	*
[Ref.: #20218]	L.acidophilus 16S rRNA gene	X61138	1379	ENA	1579 tax ID	*
[Ref.: #67770]	Lactobacillus acidophilus strain JCM_1132 16S ribosomal RNA gene, partial sequence	HM162411	1453	ENA	1579 tax ID
[Ref.: #67770]	Lactobacillus acidophilus gene for 16S ribosomal RNA, partial sequence, strain: JCM 1132	LC064893	1462	ENA	1579 tax ID

Genome sequence information:

Only first 5 entries are displayed. Click here to see all.

	Sequence accession description	Seq. accession number	Assembly level (bp)	Sequence database	Associated NCBI tax ID
[Ref.: #66792]	Lactobacillus acidophilus DSM 20079	GCA_003047065	complete	GenBank	1579 tax ID	*
[Ref.: #66792]	Lactobacillus acidophilus ATCC 4356	1579.22	wgs	PATRIC	1579 tax ID	*
[Ref.: #66792]	Lactobacillus acidophilus CIP 76.13	1226675.3	wgs	PATRIC	1423717 tax ID	*
[Ref.: #66792]	Lactobacillus acidophilus DSM 20079 = JCM 1132 = NBRC 13951	1423717.3	wgs	PATRIC	1423717 tax ID	*
[Ref.: #66792]	Lactobacillus acidophilus DSM 20079 = JCM 1132 = NBRC 13951	1423717.5	wgs	PATRIC	1423717 tax ID	*
[Ref.: #66792]	Lactobacillus acidophilus JCM 1132	1236547.3	wgs	PATRIC	1423717 tax ID	*

[Ref.: #8506]	GC-content	32.0 mol%
[Ref.: #67770]	GC-content	34.6 mol%	genome sequence analysis
[Ref.: #67770]	GC-content	32 mol%	thermal denaturation, midpoint method (Tm)

Availability in culture collections External links

[Ref.: #8506]

Culture collection no.

DSM 20079, ATCC 4356, NCDO 1748, NCIB 8690, WDCM 00098, CCUG 5917, IFO 13951, CCM 4833, JCM 1132, BCRC 10695, CECT 903, CGMCC 1.1878, CIP 76.13, HAMBI 84, KCTC 3111, KCTC 3164, LMG 13550, LMG 9433, NBRC 13951, NCCB 98067, NCFB 1748, NCIMB 8690, NCTC 12980, NRIC 1547, NRRL B-23431, NRRL B-4239, NRRL B-4495, VKM B-1660, VPI 6032, VTT E-96276

[Ref.: #20218]

Associated Passport(s) in StrainInfo

13010, 13006, 137310, 122125, 866248

Literature:

Only first 10 entries are displayed. Click here to see all.

Topic	Title	Authors	Journal	DOI	Year
Metabolism	Binding of mutagens by fractions of the cell wall skeleton of lactic acid bacteria on mutagens.	Zhang XB, Ohta Y	J Dairy Sci	10.3168/jds.S0022-0302(91)78306-9	1991	*
Metabolism	In vitro binding of mutagenic pyrolyzates to lactic acid bacterial cells in human gastric juice.	Zhang XB, Ohta Y	J Dairy Sci	10.3168/jds.S0022-0302(91)78221-0	1991	*
Pathogenicity	Superoxide dismutase activity in some strains of lactobacilli: induction by manganese.	Gonzalez SN, Apella MC, Romero N, Pesce de Ruiz Holgado AA, Oliver G	Chem Pharm Bull (Tokyo)	10.1248/cpb.37.3026	1989	*
Pathogenicity	Impact of Lactobacillus acidophilus on the normal intestinal microflora after administration of two antimicrobial agents.	Lidbeck A, Edlund C, Gustafsson JA, Kager L, Nord CE	Infection	10.1007/BF01644541	1988	*
Genetics	Colonization of a human intestine by four different genotypes of Lactobacillus acidophilus.	Sarra PG, Dellaglio F	Microbiologica		1984	*
Enzymology	S-layer protein of Lactobacillus acidophilus ATCC 4356: purification, expression in Escherichia coli, and nucleotide sequence of the corresponding gene.	Boot HJ, Kolen CP, van Noort JM, Pouwels PH	J Bacteriol	10.1128/jb.175.19.6089-6096.1993	1993	*
Metabolism	Identification, cloning, and nucleotide sequence of a silent S-layer protein gene of Lactobacillus acidophilus ATCC 4356 which has extensive similarity with the S-layer protein gene of this species.	Boot HJ, Kolen CP, Pouwels PH	J Bacteriol	10.1128/jb.177.24.7222-7230.1995	1995	*
Enzymology	Positive selection, cloning vectors for gram-positive bacteria based on a restriction endonuclease cassette.	Djordjevic GM, Klaenhammer TR	Plasmid	10.1006/plas.1996.0004	1996	*
Genetics	Structural characterization of the exopolysaccharide produced by Lactobacillus acidophilus LMG9433.	Robijn GW, Gutierrez Gallego R, van den Berg DJ, Haas H, Kamerling JP, Vliegenthart JF	Carbohydr Res	10.1016/s0008-6215(96)90799-5	1996	*
Genetics	The Lactobacillus acidophilus S-layer protein gene expression site comprises two consensus promoter sequences, one of which directs transcription of stable mRNA.	Boot HJ, Kolen CP, Andreadaki FJ, Leer RJ, Pouwels PH	J Bacteriol	10.1128/jb.178.18.5388-5394.1996	1996	*
Genetics	Interchange of the active and silent S-layer protein genes of Lactobacillus acidophilus by inversion of the chromosomal slp segment.	Boot HJ, Kolen CP, Pouwels PH	Mol Microbiol	10.1046/j.1365-2958.1996.401406.x	1996	*
Phylogeny	Isolation, partial characterization, and mode of action of Acidocin J1132, a two-component bacteriocin produced by Lactobacillus acidophilus JCM 1132.	Tahara T, Oshimura M, Umezawa C, Kanatani K	Appl Environ Microbiol	10.1128/aem.62.3.892-897.1996	1996	*
Pathogenicity	Electrotransformation of lactobacillus acidophilus group A1.	Walker DC, Aoyama K, Klaenhammer TR	FEMS Microbiol Lett	10.1111/j.1574-6968.1996.tb08163.x	1996	*
Genetics	Cloning and molecular analysis of promoter-like sequences isolated from the chromosomal DNA of Lactobacillus acidophilus ATCC 4356.	Djordjevic G, Bojovic B, Miladinov N, Topisirovic L	Can J Microbiol	10.1139/m97-009	1997	*
Phylogeny	Isolation and partial amino acid sequence of bacteriocins produced by Lactobacillus acidophilus.	Tahara T, Kanatani K	Biosci Biotechnol Biochem		1997	*
Metabolism	Improvement of lactose digestion by humans following ingestion of unfermented acidophilus milk: influence of bile sensitivity, lactose transport, and acid tolerance of Lactobacillus acidophilus.	Mustapha A, Jiang T, Savaiano DA	J Dairy Sci	10.3168/jds.S0022-0302(97)76083-1	1997	*
Metabolism	Mechanism of inhibition of tannic acid and related compounds on the growth of intestinal bacteria.	Chung KT, Lu Z, Chou MW	Food Chem Toxicol	10.1016/s0278-6915(98)00086-6	1998	*
Phylogeny	Efficiency of transcription from promoter sequence variants in Lactobacillus is both strain and context dependent.	McCracken A, Timms P	J Bacteriol	10.1128/JB.181.20.6569-6572.1999	1999	*
Genetics	Analysis of promoter sequences from Lactobacillus and Lactococcus and their activity in several Lactobacillus species.	McCracken A, Turner MS, Giffard P, Hafner LM, Timms P	Arch Microbiol	10.1007/s002030000159	2000	*
Metabolism	Antioxidative effect of intestinal bacteria Bifidobacterium longum ATCC 15708 and Lactobacillus acidophilus ATCC 4356.	Lin MY, Chang FJ	Dig Dis Sci	10.1023/a:1005577330695	2000	*
Pathogenicity	Effect of supplements with lactic acid bacteria and oligofructose on the intestinal microflora during administration of cefpodoxime proxetil.	Orrhage K, Sjostedt S, Nord CE	J Antimicrob Chemother	10.1093/jac/46.4.603	2000	*
Genetics	Molecular analysis of mutated Lactobacillus acidophilus promoter-like sequence P15.	Arsenijevic S, Topisirovic L	Can J Microbiol		2000	*
Metabolism	Acetaldehyde production and metabolism by human indigenous and probiotic Lactobacillus and Bifidobacterium strains.	Nosova T, Jousimies-Somer H, Jokelainen K, Heine R, Salaspuro M	Alcohol Alcohol	10.1093/alcalc/35.6.561	2000	*
Metabolism	The S-layer protein of Lactobacillus acidophilus ATCC 4356: identification and characterisation of domains responsible for S-protein assembly and cell wall binding.	Smit E, Oling F, Demel R, Martinez B, Pouwels PH	J Mol Biol	10.1006/jmbi.2000.4258	2001	*
Enzymology	Effects of lactic acid bacteria on the uptake and distribution of the food mutagen Trp-P-2 in mice.	Orrhage KM, Annas A, Nord CE, Brittebo EB, Rafter JJ	Scand J Gastroenterol	10.1080/003655202753416902	2002	*
Enzymology	Characterization of a cryptic plasmid from Lactobacillus fermentum KC5b and its use for constructing a stable Lactobacillus cloning vector.	Pavlova SI, Kilic AO, Topisirovic L, Miladinov N, Hatzos C, Tao L	Plasmid	10.1016/s0147-619x(02)00005-7	2002	*
Metabolism	Structural and functional analysis of the S-layer protein crystallisation domain of Lactobacillus acidophilus ATCC 4356: evidence for protein-protein interaction of two subdomains.	Smit E, Jager D, Martinez B, Tielen FJ, Pouwels PH	J Mol Biol	10.1016/s0022-2836(02)01135-x	2002	*
Pathogenicity	[Effects of para-aminobenzoic acid (PABA) on growth of Lactobacillus acidophilus].	Guo B, Zhou X, Xiao X, Li J, Li L	Hua Xi Kou Qiang Yi Xue Za Zhi		2001	*
Pathogenicity	Growth inhibition of intestinal bacteria and mutagenicity of 2-, 3-, 4-aminobiphenyls, benzidine, and biphenyl.	Chung KT, Adris P	Toxicol In Vitro	10.1016/s0887-2333(02)00131-5	2003	*
Metabolism	Live probiotics protect intestinal epithelial cells from the effects of infection with enteroinvasive Escherichia coli (EIEC).	Resta-Lenert S, Barrett KE	Gut	10.1136/gut.52.7.988	2003	*
Pathogenicity	Bacterial gene expression detected in human faeces by reverse transcription-PCR.	Fitzsimons NA, Akkermans AD, de Vos WM, Vaughan EE	J Microbiol Methods	10.1016/s0167-7012(03)00121-0	2003	*
Metabolism	Two distinct pathways for the formation of hydroxy FA from linoleic acid by lactic acid bacteria.	Kishimoto N, Yamamoto I, Toraishi K, Yoshioka S, Saito K, Masuda H, Fujita T	Lipids	10.1007/s11745-003-1188-4	2003	*
Biotechnology	Potential of selected lactic acid bacteria to produce food compatible antifungal metabolites.	De Muynck C, Leroy AI, De Maeseneire S, Arnaut F, Soetaert W, Vandamme EJ	Microbiol Res	10.1016/j.micres.2004.07.002	2004	*
Enzymology	Construction of a combined physical and genetic map of the chromosome of Lactobacillus acidophilus ATCC 4356 and characterization of the rRNA operons.	El-Osta YGA, Hillier AJ, Dobos M	Microbiology (Reading)	10.1099/mic.0.27134-0	2005	*
Phylogeny	Purification and characterisation of acidocin D20079, a bacteriocin produced by Lactobacillus acidophilus DSM 20079.	Deraz SF, Karlsson EN, Hedstrom M, Andersson MM, Mattiasson B	J Biotechnol	10.1016/j.jbiotec.2005.02.005	2005	*
Metabolism	Influence of controlled lactic fermentation on growth and sporulation of Bacillus cereus in milk.	Rossland E, Langsrud T, Sorhaug T	Int J Food Microbiol	10.1016/j.ijfoodmicro.2004.11.027	2005	*
Phylogeny	Probiotic lactobacilli and bacteraemia in Stockholm.	Sullivan A, Nord CE	Scand J Infect Dis	10.1080/00365540500449826	2006	*
Enzymology	Development of antioxidant activity in milk whey during fermentation with lactic acid bacteria.	Virtanen T, Pihlanto A, Akkanen S, Korhonen H	J Appl Microbiol	10.1111/j.1365-2672.2006.03072.x	2007	*
Metabolism	Mode of action of acidocin D20079, a bacteriocin produced by the potential probiotic strain, Lactobacillus acidophilus DSM 20079.	Deraz SF, Karlsson EN, Khalil AA, Mattiasson B	J Ind Microbiol Biotechnol	10.1007/s10295-007-0206-8	2007	*
Metabolism	The S-layer proteins of Lactobacillus crispatus strain ZJ001 is responsible for competitive exclusion against Escherichia coli O157:H7 and Salmonella typhimurium.	Chen X, Xu J, Shuai J, Chen J, Zhang Z, Fang W	Int J Food Microbiol	10.1016/j.ijfoodmicro.2006.11.007	2007	*
Pathogenicity	Basic characteristics of Sporolactobacillus inulinus BCRC 14647 for potential probiotic properties.	Huang HY, Huang SY, Chen PY, King VA, Lin YP, Tsen JH	Curr Microbiol	10.1007/s00284-006-0496-5	2007	*
Phenotype	Administration of Lactobacillus evokes coordinated changes in the intestinal expression profile of genes regulating energy homeostasis and immune phenotype in mice.	Nerstedt A, Nilsson EC, Ohlson K, Hakansson J, Thomas Svensson L, Lowenadler B, Svensson UK, Mahlapuu M	Br J Nutr	10.1017/S0007114507682907	2007	*
Pathogenicity	[Effects of Lactobacilli on regulating NF-kappaB activation and IL-8 secretion in SGC7901 cell impacted by Helicobacter pylori].	Ma FZ, Ma HS, Yu Q, Han SX	Sichuan Da Xue Xue Bao Yi Xue Ban		2007	*
Pathogenicity	Incorporation of citrus fibers in fermented milk containing probiotic bacteria.	Sendra E, Fayos P, Lario Y, Fernandez-Lopez J, Sayas-Barbera E, Perez-Alvarez JA	Food Microbiol	10.1016/j.fm.2007.09.003	2007	*
Enzymology	Molecular analysis of phenol-degrading microbial strains.	Manasiev J, Gerginova M, Yemendzhiev H, Peneva N, Alexieva Z	Z Naturforsch C J Biosci	10.1515/znc-2008-1-224	2008	*
Biotechnology	Influence of microencapsulation and spray drying on the viability of Lactobacillus and Bifidobacterium strains.	Goderska K, Czarnecki Z	Pol J Microbiol		2008	*
Enzymology	Murein hydrolase activity in the surface layer of Lactobacillus acidophilus ATCC 4356.	Prado Acosta M, Mercedes Palomino M, Allievi MC, Sanchez Rivas C, Ruzal SM	Appl Environ Microbiol	10.1128/AEM.01712-08	2008	*
Cultivation	[Initial study on the discrimination of oral microorganisms with a metabonomics method].	Xiong P, Zhou JL, Xiao LY, Kong XL, Li JY, Jia XM, Li W	Hua Xi Kou Qiang Yi Xue Za Zhi		2008	*
Enzymology	[Cloning, expression and characterization of a heterodimeric beta-galactosidase from Lactobacillus acidophilus ATCC 4356].	Pan Q, Li J, Cong Y, Liu L, Zhu J, Hu F	Wei Sheng Wu Xue Bao		2008	*
Pathogenicity	Effect of supplement with lactic-acid producing bacteria on fatigue and physical activity in patients with chronic fatigue syndrome.	Sullivan A, Nord CE, Evengard B	Nutr J	10.1186/1475-2891-8-4	2009	*
Pathogenicity	The probiotic Lactobacillus acidophilus reduces cholesterol absorption through the down-regulation of Niemann-Pick C1-like 1 in Caco-2 cells.	Huang Y, Zheng Y	Br J Nutr	10.1017/S0007114509991991	2009	*
Pathogenicity	Stimulatory role of grape pomace polyphenols on Lactobacillus acidophilus growth.	Hervert-Hernandez D, Pintado C, Rotger R, Goni I	Int J Food Microbiol	10.1016/j.ijfoodmicro.2009.09.016	2009	*
Enzymology	Functional identification of a putative beta-galactosidase gene in the special lac gene cluster of Lactobacillus acidophilus.	Pan Q, Zhu J, Liu L, Cong Y, Hu F, Li J, Yu X	Curr Microbiol	10.1007/s00284-009-9521-9	2009	*
Pathogenicity	Synergistic effects of the Lactobacillus acidophilus surface layer and nisin on bacterial growth.	Prado-Acosta M, Ruzal SM, Allievi MC, Palomino MM, Sanchez Rivas C	Appl Environ Microbiol	10.1128/AEM.01427-09	2009	*
Pathogenicity	Validation of the dorsal air pouch model to predict and examine immunostimulatory responses in the gut.	Kourelis A, Zinonos I, Kakagianni M, Christidou A, Christoglou N, Yiannaki E, Testa T, Kotzamanidis C, Litopoulou-Tzanetaki E, Tzanetakis N, Yiangou M	J Appl Microbiol	10.1111/j.1365-2672.2009.04421.x	2010	*
Pathogenicity	Immunostimulatory activity of potential probiotic yeast strains in the dorsal air pouch system and the gut mucosa.	Kourelis A, Kotzamanidis C, Litopoulou-Tzanetaki E, Papaconstantinou J, Tzanetakis N, Yiangou M	J Appl Microbiol	10.1111/j.1365-2672.2009.04651.x	2009	*
Biotechnology	Oral administration of Lactobacillus acidophilus induces IL-12 production in spleen cell culture of BALB/c mice bearing transplanted breast tumour.	Yazdi MH, Soltan Dallal MM, Hassan ZM, Holakuyee M, Agha Amiri S, Abolhassani M, Mahdavi M	Br J Nutr	10.1017/S0007114510000516	2010	*
Metabolism	Effect of prebiotics on viability and growth characteristics of probiotics in soymilk.	Yeo SK, Liong MT	J Sci Food Agric	10.1002/jsfa.3808	2010	*
Pathogenicity	Assessment of bile salt effects on s-layer production, slp gene expression and some physicochemical properties of Lactobacillus acidophilus ATCC 4356.	Khaleghi M, Kermanshahi RK, Yaghoobi MM, Zarkesh-Esfahani SH, Baghizadeh A	J Microbiol Biotechnol	JMB020-04-15	2010	*
Metabolism	Phytase activity from Lactobacillus spp. in calcium-fortified soymilk.	Tang AL, Wilcox G, Walker KZ, Shah NP, Ashton JF, Stojanovska L	J Food Sci	10.1111/j.1750-3841.2010.01663.x	2010	*
Pathogenicity	The effect of a probiotic strain (Lactobacillus acidophilus) on the plaque formation of oral Streptococci.	Tahmourespour A, Kermanshahi RK	Bosn J Basic Med Sci	10.17305/bjbms.2011.2621	2011	*
Pathogenicity	Effects of penicillin G on morphology and certain physiological parameters of Lactobacillus acidophilus ATCC 4356.	Khaleghi M, Kasra Kermanshahi R, Zarkesh-Esfahani SH	J Microbiol Biotechnol	10.4014/jmb.1012.12020	2011	*
Metabolism	Antagonistic activity of Lactobacillus acidophilus ATCC 4356 on the growth and adhesion/invasion characteristics of human Campylobacter jejuni.	Campana R, Federici S, Ciandrini E, Baffone W	Curr Microbiol	10.1007/s00284-012-0080-0	2012	*
Metabolism	The prebiotic source influences the growth, biochemical features and survival under simulated gastrointestinal conditions of the probiotic Lactobacillus acidophilus.	Nazzaro F, Fratianni F, Nicolaus B, Poli A, Orlando P	Anaerobe	10.1016/j.anaerobe.2012.03.002	2012	*
Pathogenicity	Stability of free and encapsulated Lactobacillus acidophilus ATCC 4356 in yogurt and in an artificial human gastric digestion system.	Ortakci F, Sert S	J Dairy Sci	10.3168/jds.2012-5710	2012	*
Metabolism	Evaluation of probiotic strains for development of fermented Alisma canaliculatum and their effects on broiler chickens.	Hossain ME, Ko SY, Kim GM, Firman JD, Yang CJ	Poult Sci	10.3382/ps.2012-02333	2012	*
Metabolism	Metabolism of biodiesel-derived glycerol in probiotic Lactobacillus strains.	Rivaldi JD, Sousa Silva M, Duarte LC, Ferreira AE, Cordeiro C, de Almeida Felipe Md, de Ponces Freire A, de Mancilha IM	Appl Microbiol Biotechnol	10.1007/s00253-012-4621-z	2012	*
Metabolism	Antimicrobial potential for the combination of bovine lactoferrin or its hydrolysate with lactoferrin-resistant probiotics against foodborne pathogens.	Chen PW, Jheng TT, Shyu CL, Mao FC	J Dairy Sci	10.3168/jds.2012-6112	2013	*
Metabolism	Comparison of adhesive gut bacteria composition, immunity, and disease resistance in juvenile hybrid tilapia fed two different Lactobacillus strains.	Liu W, Ren P, He S, Xu L, Yang Y, Gu Z, Zhou Z	Fish Shellfish Immunol	10.1016/j.fsi.2013.04.010	2013	*
Metabolism	Capsicum annuum enhances L-lactate production by Lactobacillus acidophilus: implication in curd formation.	Sharma S, Jain S, Nair GN, Ramachandran S	J Dairy Sci	10.3168/jds.2012-6243	2013	*
Pathogenicity	Lactobacillus acidophilus ATCC 4356 attenuates the atherosclerotic progression through modulation of oxidative stress and inflammatory process.	Chen L, Liu W, Li Y, Luo S, Liu Q, Zhong Y, Jian Z, Bao M	Int Immunopharmacol	10.1016/j.intimp.2013.05.018	2013	*
Genetics	Draft Genome Sequences of Five Strains of Lactobacillus acidophilus, Strain CIP 76.13T, Isolated from Humans, Strains CIRM-BIA 442 and CIRM-BIA 445, Isolated from Dairy Products, and Strains DSM 20242 and DSM 9126 of Unknown Origin.	Falentin H, Cousin S, Clermont D, Creno S, Ma L, Chuat V, Loux V, Rudiger P, Bizet C, Bouchier C	Genome Announc	10.1128/genomeA.00658-13	2013	*
Phylogeny	Lactobacillus apis sp. nov., from the stomach of honeybees (Apis mellifera), having an in vitro inhibitory effect on the causative agents of American and European foulbrood.	Killer J, Dubna S, Sedlacek I, Svec P	Int J Syst Evol Microbiol	10.1099/ijs.0.053033-0	2013	*
Enzymology	Molecular Cloning, Expression of minD Gene from Lactobacillus acidophilus VTCC-B-871 and Analyses to Identify Lactobacillus rhamnosus PN04 from Vietnam Hottuynia cordata Thunb.	Nguyen TH, Doan VT, Ha LD, Nguyen HN	Indian J Microbiol	10.1007/s12088-013-0384-1	2013	*
Metabolism	Shelf life stability of lactobacilli encapsulated in raspberry powder: insights into non-dairy probiotics.	Anekella K, Orsat V	Int J Food Sci Nutr	10.3109/09637486.2013.869793	2014	*
Biotechnology	Construction of a food-grade cell surface display system for Lactobacillus casei.	Qin J, Wang X, Kong J, Ma C, Xu P	Microbiol Res	10.1016/j.micres.2014.02.001	2014	*
Pathogenicity	Systematic screening of plant extracts from the Brazilian Pantanal with antimicrobial activity against bacteria with cariogenic relevance.	Brighenti FL, Salvador MJ, Delbem AC, Delbem AC, Oliveira MA, Soares CP, Freitas LS, Koga-Ito CY	Caries Res	10.1159/000357225	2014	*
Pathogenicity	Intensity and duration of in-vitro antibacterial activity of different adhesives used in orthodontics.	Passariello C, Sannino G, Petti S, Gigola P	Eur J Oral Sci	10.1111/eos.12120	2014	*
Biotechnology	Growth performance, meat yield, oxidative stability, and Fatty Acid composition of meat from broilers fed diets supplemented with a medicinal plant and probiotics.	Hossain ME, Kim GM, Lee SK, Yang CJ	Asian-Australas J Anim Sci	10.5713/ajas.2012.12090	2012	*
Metabolism	Lactobacillus acidophilus ATCC 4356 prevents atherosclerosis via inhibition of intestinal cholesterol absorption in apolipoprotein E-knockout mice.	Huang Y, Wang J, Quan G, Wang X, Yang L, Zhong L	Appl Environ Microbiol	10.1128/AEM.02926-14	2014	*
Genetics	Draft Genome Sequence of the Probiotic Strain Lactobacillus acidophilus ATCC 4356.	Palomino MM, Allievi MC, Fina Martin J, Waehner PM, Prado Acosta M, Sanchez Rivas C, Ruzal SM	Genome Announc	10.1128/genomeA.01421-14	2015	*
Biotechnology	Th1 Cytokine Production Induced by Lactobacillus acidophilus in BALB/c Mice Bearing Transplanted Breast Tumor.	Imani Fooladi AA, Yazdi MH, Pourmand MR, Mirshafiey A, Hassan ZM, Azizi T, Mahdavi M, Soltan Dallal MM	Jundishapur J Microbiol	10.5812/jjm.8(4)2015.17354	2015	*
Biotechnology	Effect of refrigerated storage on probiotic viability and the production and stability of antimutagenic and antioxidant peptides in yogurt supplemented with pineapple peel.	Sah BN, Vasiljevic T, McKechnie S, Donkor ON	J Dairy Sci	10.3168/jds.2015-9450	2015	*
Metabolism	Assessment of the in vitro antimicrobial activity of Lactobacillus species for identifying new potential antibiotics.	Dubourg G, Elsawi Z, Raoult D	Int J Antimicrob Agents	10.1016/j.ijantimicag.2015.05.011	2015	*
Pathogenicity	Membrane filter method to study the effects of Lactobacillus acidophilus and Bifidobacterium longum on fecal microbiota.	Shimizu H, Benno Y	Microbiol Immunol	10.1111/1348-0421.12332	2015	*
Biotechnology	Crystalline Bacterial Surface Layer (S-Layer) Opens Golden Opportunities for Nanobiotechnology in Textiles.	Asadi N, Chand N, Rassa M	IEEE Trans Nanobioscience	10.1109/TNB.2015.2495143	2015	*
Stress	Expression of the Mucus Adhesion Gene Mub, Surface Layer Protein Slp and Adhesion-Like Factor EF-TU of Lactobacillus acidophilus ATCC 4356 Under Digestive Stress Conditions, as Monitored with Real-Time PCR.	Ramiah K, van Reenen CA, Dicks LM	Probiotics Antimicrob Proteins	10.1007/s12602-009-9009-8	2009	*
Metabolism	Immunological mechanisms involved in probiotic-mediated protection against Citrobacter rodentium-induced colitis.	Jiang Y, Yang G, Meng F, Yang W, Hu J, Ye L, Shi C, Wang C	Benef Microbes	10.3920/BM2015.0119	2016	*
Metabolism	Influence of osmotic stress on the profile and gene expression of surface layer proteins in Lactobacillus acidophilus ATCC 4356.	Palomino MM, Waehner PM, Fina Martin J, Ojeda P, Malone L, Sanchez Rivas C, Prado Acosta M, Allievi MC, Ruzal SM	Appl Microbiol Biotechnol	10.1007/s00253-016-7698-y	2016	*
Pathogenicity	The inhibitory effect of bacteriocin produced by Lactobacillus acidophilusATCC 4356 and Lactobacillus plantarum ATCC 8014 on planktonic cells and biofilms of Serratia marcescens.	Vahedi Shahandashti R, Kasra Kermanshahi R, Ghadam P	Turk J Med Sci	10.3906/sag-1505-51	2016	*
Cultivation	Acidogenicity of dual-species biofilms of bifidobacteria and Streptococcus mutans.	de Matos BM, Brighenti FL, Do T, Beighton D, Koga-Ito CY	Clin Oral Investig	10.1007/s00784-016-1958-1	2016	*
Metabolism	[Expression, purification and activity analysis of GGDEF and EAL domain-containing proteins from Lactobacillus acidophilus].	He JH, Sun JL, Yan WJ, Wang F	Nan Fang Yi Ke Da Xue Xue Bao		2017	*
Pathogenicity	Effect of Probiotic Yogurt and Xylitol-Containing Chewing Gums on Salivary S Mutans Count.	Ghasemi E, Mazaheri R, Tahmourespour A	J Clin Pediatr Dent	10.17796/1053-4628-41.4.257	2017	*
Phylogeny	Isolation and Partial Amino Add Sequence of Bacteriocins Produced by Lactobacillus acidophilus.	Tahara T, Kanatani K	Biosci Biotechnol Biochem	10.1271/bbb.61.884	1997	*
Metabolism	Proteomics Analysis of the Adhesion Activity of Lactobacillus acidophilus ATCC 4356 Upon Growth in an Intestine-Like pH Environment.	Wu Z, Wang G, Wang W, Pan D, Peng L, Lian L	Proteomics	10.1002/pmic.201700308	2018	*
Pathogenicity	The role of probiotic Lactobacillus acidophilus ATCC 4356 bacteriocin on effect of HBsu on planktonic cells and biofilm formation of Bacillus subtilis.	Sarikhani M, Kermanshahi RK, Ghadam P, Gharavi S	Int J Biol Macromol	10.1016/j.ijbiomac.2018.03.087	2018	*
Metabolism	Strategic ultrasound-induced stress response of lactic acid bacteria on enhancement of beta-glucosidase activity for bioconversion of isoflavones in soymilk.	Liu WS, Yang CY, Fang TJ	J Microbiol Methods	10.1016/j.mimet.2018.04.006	2018	*
Pathogenicity	Biochemical characterization of a recombinant Lactobacillus acidophilus strain expressing exogenous FomA protein.	Ma L, Li F, Zhang X, Feng X	Arch Oral Biol	10.1016/j.archoralbio.2018.04.016	2018	*
Metabolism	Lactobacillus acidophilus Alleviated Salmonella-Induced Goblet Cells Loss and Colitis by Notch Pathway.	Wu H, Ye L, Lu X, Xie S, Yang Q, Yu Q	Mol Nutr Food Res	10.1002/mnfr.201800552	2018	*
Biotechnology	Production of sesaminol and antioxidative activity of fermented sesame with Lactobacillus plantarum P8, Lactobacillus acidophilus ATCC 4356, Streptococcus thermophilus S10.	Bae JJ, Yeon SJ, Park WJ, Hong GE, Lee CH	Food Sci Biotechnol	10.1007/s10068-016-0030-x	2016	*
Pathogenicity	The survival of irradiated lactobacilli in the simulated gastrointestinal conditions with antibiotic ceftazidime.	Soghomonyan D, Trchounian A	Lett Appl Microbiol	10.1111/lam.13080	2018	*
Enzymology	Evaluation of beta-galactosidase from Lactobacillus acidophilus as biocatalyst for galacto-oligosaccharides synthesis: Product structural characterization and enzyme immobilization.	Carevic M, Vukasinovic-Sekulic M, Corovic M, Rogniaux H, Ropartz D, Velickovic D, Bezbradica D	J Biosci Bioeng	10.1016/j.jbiosc.2018.06.003	2018	*
Metabolism	Blocking HIV-1 Infection by Chromosomal Integrative Expression of Human CD4 on the Surface of Lactobacillus acidophilus ATCC 4356.	Wei W, Wiggins J, Hu D, Vrbanac V, Bowder D, Mellon M, Tager A, Sodroski J, Xiang SH	J Virol	10.1128/JVI.01830-18	2019	*
Enzymology	Effect of lactic acid bacteria on mercury toxicokinetics.	Jadan-Piedra C, Crespo A, Monedero V, Velez D, Devesa V, Zuniga M	Food Chem Toxicol	10.1016/j.fct.2019.04.001	2019	*
Metabolism	Exploring lectin-like activity of the S-layer protein of Lactobacillus acidophilus ATCC 4356.	Fina Martin J, Palomino MM, Cutine AM, Modenutti CP, Fernandez Do Porto DA, Allievi MC, Zanini SH, Marino KV, Barquero AA, Ruzal SM	Appl Microbiol Biotechnol	10.1007/s00253-019-09795-y	2019	*
Stress	The effects of the Lactobacillus acidophilus ATCC 4356 on the oxidative stress of reproductive system in diabetic male rats.	Sheikh Hosseini S, Gol A, Khaleghi M	Int J Reprod Biomed	10.18502/ijrm.v17i7.4861	2019	*
Cultivation	Topical Delivery of Lactobacillus Culture Supernatant Increases Survival and Wound Resolution in Traumatic Acinetobacter baumannii Infections.	Stanbro J, Park JM, Bond M, Stockelman MG, Simons MP, Watters C	Probiotics Antimicrob Proteins	10.1007/s12602-019-09603-z	2020	*
Pathogenicity	Antimicrobial Effect of Orthodontic Materials on Cariogenic Bacteria Streptococcus mutans and Lactobacillus acidophilus.	Krasniqi S, Sejdini M, Stubljar D, Jukic T, Ihan A, Aliu K, Aliu X	Med Sci Monit Basic Res	10.12659/MSMBR.920510	2020	*
Pathogenicity	Multifunctional Acidocin 4356 Combats Pseudomonas aeruginosa through Membrane Perturbation and Virulence Attenuation: Experimental Results Confirm Molecular Dynamics Simulation.	Modiri S, Kasra Kermanshahi R, Soudi MR, Arab SS, Khammari A, Cousineau B, Vali H, Zahiri HS, Noghabi KA	Appl Environ Microbiol	10.1128/AEM.00367-20	2020	*
Metabolism	Characterization of the sortase A from Lactobacillus acidophilus ATCC 4356 involved in adherence to intestinal cells.	Wu Z, Wu J, Lang F, Cai Z, Zeng X, Guo Y, Liu X, Pan D	Future Microbiol	10.2217/fmb-2019-0219	2020	*
Pathogenicity	Effects of Pretreatments on Patulin Removal from Apple Juices Using Lactobacilli: Binding Stability in Simulated Gastrointestinal Condition and Modeling.	Zoghi A, Darani KK, Hekmatdoost A	Probiotics Antimicrob Proteins	10.1007/s12602-020-09666-3	2021	*
Metabolism	Fermented yellow mombin juice using Lactobacillus acidophilus NRRL B-4495: Chemical composition, bioactive properties and survival in simulated gastrointestinal conditions.	Ribeiro ESS, Damasceno KSFSC, Dantas LMDC, Azevedo WM, Leite PIP, Assis CF, Sousa Junior FC	PLoS One	10.1371/journal.pone.0239392	2020	*
Metabolism	Strategies to display heterologous proteins on the cell surface of lactic acid bacteria using as anchor the C-terminal domain of Lactobacillus acidophilus SlpA.	Gordillo TB, Palumbo MC, Allievi MC, Fernandez Do Porto DA, Ruzal SM, Palomino MM	World J Microbiol Biotechnol	10.1007/s11274-020-02945-9	2020	*
Pathogenicity	Evaluation of Anti-Tumor Potential of Lactobacillus acidophilus ATCC4356 Culture Supernatants in MCF-7 Breast Cancer.	Behzadi R, Hormati A, Eivaziatashbeik K, Ahmadpour S, Khodadust F, Zaboli F, Fattahi E, Jahanban-Esfahlan R, Seidi K	Anticancer Agents Med Chem	10.2174/1871520621666201207085239	2021	*
Enzymology	Precision modification of the human gut microbiota targeting surface-associated proteins.	Marcos-Fernandez R, Ruiz L, Blanco-Miguez A, Margolles A, Sanchez B	Sci Rep	10.1038/s41598-020-80187-3	2021	*
Metabolism	Specific Lactobacillus probiotic strains decrease transepithelial glucose transport through GLUT2 downregulation in intestinal epithelial cell models.	Primec M, Skorjanc D, Langerholc T, Micetic-Turk D, Gorenjak M	Nutr Res	10.1016/j.nutres.2020.11.008	2020	*
Pathogenicity	Protective effect of the probiotic Lactobacillus acidophilus ATCC 4356 in BALB/c mice infected with Toxocara canis.	Cadore PS, Walcher DL, Sousa NFGC, Martins LHR, Hora VPD, Groll AV, Moura MQ, Berne MEA, Avila LFDC, Scaini CJ	Rev Inst Med Trop Sao Paulo	10.1590/S1678-9946202163009	2021	*
Enzymology	Coating function and stabilizing effects of surface layer protein from Lactobacillus acidophilus ATCC 4356 on liposomes.	Meng J, Wang YY, Hao YP, Zhang SB, Ding CH, You YZ	Int J Biol Macromol	10.1016/j.ijbiomac.2021.04.135	2021	*
Pathogenicity	Lactobacillus acidophilus ATCC 4356 Alleviates Renal Ischemia-Reperfusion Injury Through Antioxidant Stress and Anti-inflammatory Responses and Improves Intestinal Microbial Distribution.	Zhang P, Han X, Zhang X, Zhu X	Front Nutr	10.3389/fnut.2021.667695	2021	*
Pathogenicity	Lactobacillus acidophilus ATCC 4356 Exopolysaccharides Suppresses Mediators of Inflammation through the Inhibition of TLR2/STAT-3/P38-MAPK Pathway in DEN-Induced Hepatocarcinogenesis in Rats.	Khedr OMS, El-Sonbaty SM, Moawed FSM, Kandil EI, Abdel-Maksoud BE	Nutr Cancer	10.1080/01635581.2021.1934490	2021	*
Stress	Stress Effect of Food Matrices on Viability of Probiotic Cells during Model Digestion.	Matouskova P, Hoova J, Rysavka P, Marova I	Microorganisms	10.3390/microorganisms9081625	2021	*
Phylogeny	Comparison of 16S rRNA Gene Based Microbial Profiling Using Five Next-Generation Sequencers and Various Primers.	Park C, Kim SB, Choi SH, Kim S	Front Microbiol	10.3389/fmicb.2021.715500	2021	*
Pathogenicity	Effectiveness of two probiotics in preventing necrotising enterocolitis in a cohort of very-low-birth-weight premature new-borns.	Uberos J, Campos-Martinez A, Fernandez-Marin E, Millan IC, Lopez AR, Blanca-Jover E	Benef Microbes	10.3920/BM2021.0088	2021	*
Biotechnology	Growth Optimization of Lactobacillus acidophilus for Production of Antimicrobial Peptide Acidocin 4356: Scale up from Flask to Lab-Scale Fermenter.	Modiri S, Kasra Kermanshahi R, Reza Soudi M, Dad N, Ebadi M, Shahbani Zahiri H, Akbari Noghabi K	Iran J Biotechnol	10.30498/ijb.2021.218725.2686	2021	*
Genetics	Complete genome sequencing and comparative genomic analysis of Lactobacillus acidophilus C5 as a potential canine probiotics.	Son S, Lee R, Park SM, Lee SH, Lee HK, Kim Y, Shin D	J Anim Sci Technol	10.5187/jast.2021.e126	2021	*
Metabolism	Differential Effects of Transition Metals on Growth and Metal Uptake for Two Distinct Lactobacillus Species.	Huynh U, Qiao M, King J, Trinh B, Valdez J, Haq M, Zastrow ML	Microbiol Spectr	10.1128/spectrum.01006-21	2022	*
Metabolism	Heterologous expression and biological characteristics of UGPases from Lactobacillus acidophilus.	Zhen N, Ye C, Shen Q, Zeng X, Wu Z, Guo Y, Cai Z, Pan D	Appl Microbiol Biotechnol	10.1007/s00253-022-11856-8	2022	*
Metabolism	Effect of soybean oligopeptide on the growth and metabolism of Lactobacillus acidophilus JCM 1132.	Li W, Zhang Y, Li H, Zhang C, Zhang J, Uddin J, Liu X	RSC Adv	10.1039/d0ra01632b	2020	*
Metabolism	Levilactobacillus brevis from carnivores can ameliorate hypercholesterolemia: In vitro and in vivo mechanistic evidence.	Munir A, Javed GA, Javed S, Arshad N	J Appl Microbiol	10.1111/jam.15678	2022	*
	A Collagen-Binding S-Layer Protein in Lactobacillus crispatus.	Toba T, Virkola R, Westerlund B, Bjorkman Y, Sillanpaa J, Vartio T, Kalkkinen N, Korhonen TK	Appl Environ Microbiol	10.1128/aem.61.7.2467-2471.1995	1995	*
	Lactobacillus Acidophilus-Derived Biosurfactant Effect on GTFB and GTFC Expression Level in Streptococcus Mutans Biofilm Cells.	Tahmourespour A, Salehi R, Kasra Kermanshahi R	Braz J Microbiol	10.1590/S1517-83822011000100042	2011	*
	Studying the Stability of S-Layer Protein of Lactobacillus Acidophilus ATCC 4356 in Simulated Gastrointestinal Fluids Using SDS-PAGE and Circular Dichroism.	Eslami N, Kermanshahi RK, Erfan M	Iran J Pharm Res		2013	*
	Lactobacillus acidophilus ATCC 4356 inhibits biofilm formation by C. albicans and attenuates the experimental candidiasis in Galleria mellonella.	Vilela SF, Barbosa JO, Rossoni RD, Santos JD, Prata MC, Anbinder AL, Jorge AO, Junqueira JC	Virulence	10.4161/21505594.2014.981486	2015	*
	The inhibitory effect of a Lactobacillus acidophilus derived biosurfactant on biofilm producer Serratia marcescens.	Shokouhfard M, Kermanshahi RK, Shahandashti RV, Feizabadi MM, Teimourian S	Iran J Basic Med Sci		2015	*
	Antibacterial Activity of MTA Fillapex and AH 26 Root Canal Sealers at Different Time Intervals.	Jafari F, Samadi Kafil H, Jafari S, Aghazadeh M, Momeni T	Iran Endod J	10.7508/iej.2016.03.009	2016	*
	Effect of Non-Dairy Food Matrices on the Survival of Probiotic Bacteria during Storage.	Min M, Bunt CR, Mason SL, Bennett GN, Hussain MA	Microorganisms	10.3390/microorganisms5030043	2017	*
	A Metabolomics Approach Reveals Immunomodulatory Effects of Proteinaceous Molecules Derived From Gut Bacteria Over Human Peripheral Blood Mononuclear Cells.	Cambeiro-Perez N, Hidalgo-Cantabrana C, Moro-Garcia MA, Alonso-Arias R, Simal-Gandara J, Sanchez B, Martinez-Carballo E	Front Microbiol	10.3389/fmicb.2018.02701	2018	*
	[The effect of Streptococcus mutans luxS gene on mixed-species biofilm communities].	He ZY, Zhou W, Huang ZW, Liang JP, Jiang W	Shanghai Kou Qiang Yi Xue		2019	*
	Effect of Prebiotics-Enhanced Probiotics on the Growth of Streptococcus mutans.	Nunpan S, Suwannachart C, Wayakanon K	Int J Microbiol	10.1155/2019/4623807	2019	*
	Antifungal and Antivirulence Activity of Vaginal Lactobacillus Spp. Products against Candida Vaginal Isolates.	Itapary Dos Santos C, Ramos Franca Y, Duarte Lima Campos C, Quaresma Bomfim MR, Oliveira Melo B, Assuncao Holanda R, Santos VL, Gomes Monteiro S, Buozzi Moffa E, Souza Monteiro A, Andrade Monteiro C, Monteiro-Neto V	Pathogens	10.3390/pathogens8030150	2019	*
	Lactobacillus acidophilus JCM 1132 Strain and Its Mutant with Different Bacteriocin-Producing Behaviour Have Various in Situ Effects on the Gut Microbiota of Healthy Mice.	Wang G, Yu Y, Garcia-Gutierrez E, Jin X, He Y, Wang L, Tian P, Liu Z, Zhao J, Zhang H, Chen W	Microorganisms	10.3390/microorganisms8010049	2019	*
	Effects of heat shock treatment on the survival rate of Lactobacillus acidophilus after freeze-drying.	Zhen N, Zeng X, Wang H, Yu J, Pan D, Wu Z, Guo Y	Food Res Int	10.1016/j.foodres.2020.109507	2020	*
	Lead and cadmium biosorption from milk by Lactobacillus acidophilus ATCC 4356.	Massoud R, Khosravi-Darani K, Sharifan A, Asadi G, Zoghi A	Food Sci Nutr	10.1002/fsn3.1825	2020	*
	Development of an Antigen Delivery Platform Using Lactobacillus acidophilus Decorated With Heterologous Proteins: A Sheep in Wolf's Clothing Story.	Uriza PJ, Trautman C, Palomino MM, Fina Martin J, Ruzal SM, Roset MS, Briones G	Front Microbiol	10.3389/fmicb.2020.509380	2020	*
	Comparison of microbial adhesion and biofilm formation on orthodontic wax materials; an in vitro study.	Bozkurt AP, Unlu O, Demirci M	J Dent Sci	10.1016/j.jds.2020.04.011	2020	*
	Investigation of Antibacterial Activity and Probiotic Properties of Strains Belonging to Lactobacillus and Bifidobacterium Genera for Their Potential Application in Functional Food and Feed Products.	Cizeikiene D, Jagelaviciute J	Probiotics Antimicrob Proteins	10.1007/s12602-021-09777-5	2021	*
	Microencapsulation of Omeprazole by Lactobacillus acidophilus ATCC 4356 Surface Layer Protein and Evaluation of its Stability in Acidic Condition.	Mobarak Qamsari E, Kermanshahi RK, Erfan M, Ghadam P	Iran J Pharm Res	10.22037/ijpr.2019.111681.13306	2020	*
	Encapsulation of Lactobacillus in Low-Methoxyl Pectin-Based Microcapsules Stimulates Biofilm Formation: Enhanced Resistances to Heat Shock and Simulated Gastrointestinal Digestion.	He C, Sampers I, Van de Walle D, Dewettinck K, Raes K	J Agric Food Chem	10.1021/acs.jafc.1c00719	2021	*
	Antagonistic and Immunomodulant Effects of Two Probiotic Strains of Lactobacillus on Clinical Strains of Helicobacter pylori.	Taghizadeh S, Falsafi T, Kermanshahi RK, Ramezani R	Galen Med J	10.31661/gmj.v9i0.1794	2020	*
	Development of a spray-dried conjugated whey protein hydrolysate powder with entrapped probiotics.	Minj S, Anand S	J Dairy Sci	10.3168/jds.2021-20978	2021	*
	Antimicrobial Efficacy of Green Synthesis of Silver Nanoparticles against Cariogenic Pathogens - An In vitro Study.	Chittrarasu M, Ahamed AS, Ravi V	J Pharm Bioallied Sci	10.4103/jpbs.jpbs_338_21	2021	*
	Dietary Lactobacillus acidophilus ATCC 4356 Relieves the Impacts of Aflatoxin B1 Toxicity on the Growth Performance, Hepatorenal Functions, and Antioxidative Capacity of Thinlip Grey Mullet (Liza ramada) (Risso 1826).	Khalafalla MM, Zayed NFA, Amer AA, Soliman AA, Zaineldin AI, Gewaily MS, Hassan AM, Van Doan H, Tapingkae W, Dawood MAO	Probiotics Antimicrob Proteins	10.1007/s12602-021-09888-z	2022	*
	Biochemical composition, antimicrobial and antifungal activities assessment of the fermented medicinal plants extract using lactic acid bacteria.	Gadhoumi H, Hayouni ELA, Martinez-Rojas E, Yeddes W, Tounsi MS	Arch Microbiol	10.1007/s00203-022-02985-9	2022	*
	Technological Properties and Composition of Enzymatically Modified Cranberry Pomace.	Jagelaviciute J, Basinskiene L, Cizeikiene D, Syrpas M	Foods	10.3390/foods11152321	2022	*
	Use of Selected Lactic Acid Bacteria for the Fermentation of Legume-Based Water Extracts.	Demarinis C, Verni M, Pinto L, Rizzello CG, Baruzzi F	Foods	10.3390/foods11213346	2022	*

References

#8506

Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 20079

#20215

Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 )

#20218

Verslyppe, B., De Smet, W., De Baets, B., De Vos, P., Dawyndt P.: StrainInfo introduces electronic passports for microorganisms.. Syst Appl Microbiol. 37: 42 - 50 2014 ( DOI 10.1016/j.syapm.2013.11.002 , PubMed 24321274 )

#22927

Elise Cachat, Fergus G. Priest: Lactobacillus suntoryeus sp. nov., isolated from malt whisky distilleries. IJSEM 55: 31 - 34 2005 ( DOI 10.1099/ijs.0.63266-0 , PubMed 15653849 )

#22928

J. L. JOHNSON, C. F. PHELPS, C. S. CUMMINS, J. LONDON, F. GASSER: Taxonomy of the Lactobacillus acidophilus Group. IJSEM 30: 53 - 68 1980 ( DOI 10.1099/00207713-30-1-53 )

#41980 ; Curators of the CIP;
#44877 Culture Collection University of Gothenburg (CCUG) ; Curators of the CCUG; CCUG 5917

#66792

Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) .

#67770 Japan Collection of Microorganism (JCM) ; Curators of the JCM;

#68371

Automatically annotated from API 50CH acid .

#68379

Automatically annotated from API Coryne .

#69479

João F Matias Rodrigues, Janko Tackmann,Gregor Rot, Thomas SB Schmidt, Lukas Malfertheiner, Mihai Danaila,Marija Dmitrijeva, Daniela Gaio, Nicolas Näpflin and Christian von Mering. University of Zurich.: MicrobeAtlas 1.0 beta .

* These data were automatically processed and therefore are not curated

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