Name: Roseburia hominis A2-183
Creator: BacDive
License: http://creativecommons.org/licenses/by-nc/4.0/

Strain identifier

BacDive ID: 6367

Type strain:

Species: Roseburia hominis

Strain Designation: A2-183

Culture col. no.: DSM 16839, CIP 109406, JCM 17582, NCIMB 14029, BCRC 81266

Strain history: DSM 16839 <-- S. Duncan A2-183 <-- A. Barcenilla.

NCBI tax ID(s): 301301 (species)

SI-ID 237167

NCIMB 14029, DSM 16839, CIP 109406

Other strains from Roseburia hominis

R. hominis JCM 31337

Section

Roseburia hominis A2-183 is an anaerobe, mesophilic bacterium that was isolated from human faecal sample.

anaerobe
mesophilic
16S sequence
Bacteria
genome sequence

Information on the name and the taxonomic classification. Name and taxonomic classification

	Last LPSN update	14-12-2023 (DD-MM-YYYY)
	Domain	"Bacteria"
	Phylum	*Bacillota*
	Class	*Clostridia*
	Order	*Eubacteriales*
	Family	*Lachnospiraceae*
	Genus	*Roseburia*
	Species	**Roseburia hominis**
	Full Scientific Name (LPSN)	Roseburia hominis Duncan et al. 2006

Information on culture and growth conditions Culture and growth conditions

[Ref.: #6625]

Culture medium

BIFIDOBACTERIUM MEDIUM (DSMZ Medium 58)

[Ref.: #6625]

Culture medium growth

[Ref.: #6625]

Culture medium link

Medium recipe at MediaDive

[Ref.: #6625]

Culture medium composition

expand / minimize

	Temperatures	Kind of temperature		Temperature
[Ref.: #6625]			growth	37 °C
[Ref.: #67770]			growth	37 °C

[Ref.: #6625]	Temperature range	mesophilic
[Ref.: #67770]	Temperature range	mesophilic

Information on physiology and metabolism Physiology and metabolism

[Ref.: #6625]

Oxygen tolerance

anaerobe

	Metabolite	Utilization activity	Kind of utilization tested
[Ref.: #68380]	arginine ChEBI	-	hydrolysis	* from API rID32A
[Ref.: #68380]	D-mannose ChEBI	-	fermentation	* from API rID32A
[Ref.: #68380]	L-glutamate ChEBI	-	degradation	* from API rID32A
[Ref.: #68380]	nitrate ChEBI	-	reduction	* from API rID32A
[Ref.: #68380]	tryptophan ChEBI	-	energy source	* from API rID32A
[Ref.: #68380]	urea ChEBI	-	hydrolysis	* from API rID32A

	Metabolite production	Metabolite	Production
[Ref.: #68380]		indole ChEBI	no	* from API rID32A

	Physiological tests	Metabolite	Indole test
[Ref.: #68380]		indole ChEBI	-	* from API rID32A

	Enzyme	Enzyme activity	EC number
[Ref.: #68380]	alanine arylamidase	-	3.4.11.2	* from API rID32A
[Ref.: #68380]	alkaline phosphatase	-	3.1.3.1	* from API rID32A
[Ref.: #68380]	alpha-fucosidase	-	3.2.1.51	* from API rID32A
[Ref.: #68380]	alpha-galactosidase	+	3.2.1.22	* from API rID32A
[Ref.: #68380]	arginine dihydrolase	-	3.5.3.6	* from API rID32A
[Ref.: #68380]	beta-galactosidase	+	3.2.1.23	* from API rID32A
[Ref.: #68380]	beta-Galactosidase 6-phosphate	-		* from API rID32A
[Ref.: #68380]	glutamate decarboxylase	-	4.1.1.15	* from API rID32A
[Ref.: #68380]	glutamyl-glutamate arylamidase	-		* from API rID32A
[Ref.: #68380]	glycin arylamidase	-		* from API rID32A
[Ref.: #68380]	histidine arylamidase	-		* from API rID32A
[Ref.: #68380]	L-arginine arylamidase	-		* from API rID32A
[Ref.: #68380]	leucine arylamidase	-	3.4.11.1	* from API rID32A
[Ref.: #68380]	leucyl glycin arylamidase	-	3.4.11.1	* from API rID32A
[Ref.: #68380]	N-acetyl-beta-glucosaminidase	-	3.2.1.52	* from API rID32A
[Ref.: #68380]	phenylalanine arylamidase	-		* from API rID32A
[Ref.: #68380]	proline-arylamidase	-	3.4.11.5	* from API rID32A
[Ref.: #68380]	pyrrolidonyl arylamidase	-	3.4.19.3	* from API rID32A
[Ref.: #68380]	serine arylamidase	-		* from API rID32A
[Ref.: #68380]	tryptophan deaminase	-	4.1.99.1	* from API rID32A
[Ref.: #68380]	tyrosine arylamidase	-		* from API rID32A
[Ref.: #68380]	urease	-	3.5.1.5	* from API rID32A
	Only first 10 entries are displayed. Click here to see all.

API® rID32A:

Note that the displayed test results represent raw data and therefore may deviate!

	API ID	Urease/urea hydrolysisURE	Arginine dihydrolaseADH (Arg)	alpha-Galactosidasealpha GAL	beta-Galactosidasebeta GAL	beta-Galactosidase 6-phosphatebeta GP	alpha-Glucosidasealpha GLU	beta-Glucosidasebeta GLU	alpha-Arabinosidasealpha ARA	beta-Glucuronidasebeta GUR	beta-N-Acetyl-beta-glucosaminidasebeta NAG	Fermentation of D-mannoseMNE	Fermentation of raffinoseRAF	Glutamate decarboxylaseGDC	alpha-Fucosidasealpha FUC	Reduction of nitrateNIT	Indole productionIND	Alkaline phosphatasePAL	L-arginine arylamidaseArgA	Proline arylamidaseProA	Leucyl glycin arylamidaseLGA	Phenylalanine arylamidasePheA	Leucine arylamidaseLeuA	Pyrrolidonyl arylamidasePyrA	Tyrosine arylamidaseTyrA	Alanine arylamidaseAlaA	Glycin arylamidaseGlyA	Histidine arylamidaseHisA	Glutamyl-glutamate arylamidaseGGA	Serine arylamidaseSerA
[Ref.: #6625]	12634	-	-	+	+	-	-	+/-	-	-	-	-	+	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
[Ref.: #6625]	12633	-	-	+	+	-	+/-	+	+/-	+/-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-

Information on isolation source, the sampling and environmental conditions Isolation, sampling and environmental information

[Ref.: #6625]	Sample type/isolated from	human faecal sample
[Ref.: #6625]	Geographic location (country and/or sea, region)	Scotland, Aberdeen
[Ref.: #6625]	Country	United Kingdom
[Ref.: #6625]	Country ISO 3 Code	GBR
[Ref.: #6625]	Continent	Europe

[Ref.: #67770]	Sample type/isolated from	Human feces in Aberdeen
[Ref.: #67770]	Geographic location (country and/or sea, region)	Scotland
[Ref.: #67770]	Country	United Kingdom
[Ref.: #67770]	Country ISO 3 Code	GBR
[Ref.: #67770]	Continent	Europe
* marker position based on {}

Isolation sources categories

#Host	#Human	-
#Host Body Product	#Gastrointestinal tract	#Feces (Stool)

What are isolation sources categories?

[Ref.: #69479]

Global distribution of 16S sequence AB661434 (>99% sequence identity) for Roseburia hominis subclade from Microbeatlas

Aquatic Samples	676
Soil Samples	184
Animal Samples	56516
Plant Samples	92
Total Samples	57468

Information on possible application of the strain and its possible interaction with e.g. potential hosts Safety information

[Ref.: #6625]

Biosafety level

Risk group (German classification)
According to TRBA 466

Information on genomic background e.g. entries in nucleic sequence databass Sequence information

16S Sequence information:

	Sequence accession description	Seq. accession number	Sequence length (bp)	Sequence database	Associated NCBI tax ID
[Ref.: #67770]	Roseburia hominis gene for 16S ribosomal RNA, partial sequence, strain: JCM 17582	AB661434	1493	ENA	301301 tax ID
[Ref.: #6625]	Roseburia hominis A2-183 16S rRNA gene, type strain A2-183T	AJ270482	1485	ENA	585394 tax ID

Genome sequence information:

	Sequence accession description	Seq. accession number	Assembly level	Sequence database	Associated NCBI tax ID
[Ref.: #66792]	Roseburia hominis A2-183	GCA_000225345	complete	GenBank	585394 tax ID	*
[Ref.: #66792]	Roseburia hominis A2-183	585394.18	complete	PATRIC	585394 tax ID	*
[Ref.: #66792]	Roseburia hominis A2-183, DSM 16839	2511231128	complete	JGI IMG/M	585394 tax ID	*

[Ref.: #6625]	GC-content	47.4 mol%
[Ref.: #67770]	GC-content	47.4 mol%	high performance liquid chromatography (HPLC)

Data predicted using genome information as a basis Genome-based predictions

	Trait	Prediction	Confidence in %	In training data
	Predictions from Diaspora project based on: Roseburia hominis A2-183 A2-183 NCBI: GCA_000225345.1
[Ref.: #69480]	motile	yes	78.484	no
[Ref.: #69480]	flagellated	no	56.387	no
[Ref.: #69480]	gram-positive	yes	82.953	no
[Ref.: #69480]	anaerobic	yes	99.999	yes
[Ref.: #69480]	aerobic	no	99.279	yes
[Ref.: #69480]	halophile	no	90.03	no
[Ref.: #69480]	spore-forming	yes	67.561	no
[Ref.: #69480]	thermophile	no	89.441	no
[Ref.: #69480]	glucose-util	yes	88.51	no
[Ref.: #69480]	glucose-ferment	yes	77.866	no

Availability in culture collections External links

[Ref.: #6625]

Culture collection no.

DSM 16839, CIP 109406, JCM 17582, NCIMB 14029, BCRC 81266

[Ref.: #75840]

SI-ID 237167

Literature:

Only first 10 entries are displayed. Click here to see all.

Topic	Title	Authors	Journal	DOI	Year
Phylogeny	Pararoseburia lenta gen. nov., sp. nov. isolated from human faeces.	Abdugheni R, Wang YJ, Li DH, Du MX, Liu C, Zhou N, Liu SJ	Int J Syst Evol Microbiol	10.1099/ijsem.0.005371	2022	*
Genetics	Complete Genome Sequence of the Human Gut Symbiont Roseburia hominis.	Travis AJ, Kelly D, Flint HJ, Aminov RI	Genome Announc	10.1128/genomeA.01286-15	2015	*
Metabolism	In vitro kinetics of prebiotic inulin-type fructan fermentation by butyrate-producing colon bacteria: implementation of online gas chromatography for quantitative analysis of carbon dioxide and hydrogen gas production.	Falony G, Verschaeren A, De Bruycker F, De Preter V, Verbeke K, Leroy F, De Vuyst L	Appl Environ Microbiol	10.1128/AEM.00876-09	2009	*
Metabolism	Mechanism of conjugated linoleic acid and vaccenic acid formation in human faecal suspensions and pure cultures of intestinal bacteria.	McIntosh FM, Shingfield KJ, Devillard E, Russell WR, Wallace RJ	Microbiology (Reading)	10.1099/mic.0.022921-0	2009	*
Metabolism	Distribution of beta-glucosidase and beta-glucuronidase activity and of beta-glucuronidase gene gus in human colonic bacteria.	Dabek M, McCrae SI, Stevens VJ, Duncan SH, Louis P	FEMS Microbiol Ecol	10.1111/j.1574-6941.2008.00520.x	2008	*
Phylogeny	Proposal of Roseburia faecis sp. nov., Roseburia hominis sp. nov. and Roseburia inulinivorans sp. nov., based on isolates from human faeces.	Duncan SH, Aminov RI, Scott KP, Louis P, Stanton TB, Flint HJ	Int J Syst Evol Microbiol	10.1099/ijs.0.64098-0	2006	*
	Human Gut Symbiont Roseburia hominis Promotes and Regulates Innate Immunity.	Patterson AM, Mulder IE, Travis AJ, Lan A, Cerf-Bensussan N, Gaboriau-Routhiau V, Garden K, Logan E, Delday MI, Coutts AGP, Monnais E, Ferraria VC, Inoue R, Grant G, Aminov RI	Front Immunol	10.3389/fimmu.2017.01166	2017	*

References

#6625

Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 16839

#20215

Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 )

#66792

Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) .

#67770 Japan Collection of Microorganism (JCM) ; Curators of the JCM;

#68380

Automatically annotated from API rID32A .

#69479

João F Matias Rodrigues, Janko Tackmann,Gregor Rot, Thomas SB Schmidt, Lukas Malfertheiner, Mihai Danaila,Marija Dmitrijeva, Daniela Gaio, Nicolas Näpflin and Christian von Mering. University of Zurich.: MicrobeAtlas 1.0 beta .

#69480

Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Predictions based on genome sequence made in the Diaspora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) .

#75840

Reimer, L.C., Lissin, A.,Schober, I., Witte,J.F., Podstawka, A., Lüken, H., Bunk, B.,Overmann, J.: StrainInfo: A central database for resolving microbial strain identifiers . ( DOI 10.60712/SI-ID237167.1 )

* These data were automatically processed and therefore are not curated

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Roseburia hominis A2-183 A2-183

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