Haloferax volcanii (DSM 3757, ATCC 29605, CCM 2852)

Name: Haloferax volcanii (DSM 3757, ATCC 29605, CCM 2852)
Creator: BacDive
License: http://creativecommons.org/licenses/by/4.0/

BacDive ID 5933

Type strain

Strain Designation DS 2, DS2

Culture col. no. DSM 3757 ATCC 29605 CCM 2852 NCIMB 2012 NCMB 2012 9 more

NCBI tax ID(s) 309800 2246

Special Collections DSMZ JCM

History DSMZ <- B.J. Tindall <- NCMB <- H. Larsen, DS 2 JCM <-- NCIMB 2012 <-- H. Larsen DS2.

Links

Haloferax volcanii DS 2 is an archaeon that was isolated from bottom sediment, 1 m below surface.

genome sequence 16S sequence Archaea

Name and taxonomic classification

SI-ID 39610

ATCC 29605,IFO 14742,NCMB 2012,DSM 3757,CCM 2852,JCM 8879,NCIMB 2012,VKM B-1768,VKM B-1539,LMD 85.50,AS 1.2150,NBRC 14742,NCCB 85050,IAM 13648,CGMCC 1.2150

@ref 20215

Last LPSN update 2026-05-29 08:26:17

Domain Archaea

Phylum Methanobacteriota

Class Halobacteria

Order Halobacteriales

Family Haloferacaceae

Genus Haloferax

Species Haloferax volcanii

Full scientific name Haloferax volcanii (Mullakhanbhai and Larsen 1975) Torreblanca et al. 1986

Synonyms (6)

Halobacterium volcanii
Haloferax lucentensis
"Haloferax alicantei"
Haloferax alexandrinus
Haloferax lucentense
Haloferax alexandrinum

BacDive ID	Other strains from **Haloferax volcanii** (1)	Type strain
5934	H. volcanii WFD II, DSM 5716

Morphology

Culture and growth conditions

Culture medium

@ref	Name	Growth	Medium link	Composition
1343	HALOBACTERIA MEDIUM (DSMZ Medium 372)		Medium recipe at MediaDive	Name: HALOBACTERIA MEDIUM (DSMZ Medium 372) Composition: NaCl 200.0 g/l MgSO4 x 7 H2O 20.0 g/l Agar 20.0 g/l Yeast extract 5.0 g/l Casamino acids 5.0 g/l Na3-citrate 3.0 g/l KCl 2.0 g/l Na glutamate 1.0 g/l FeCl2 x 4 H2O 0.036 g/l MnCl2 x 4 H2O 0.00036 g/l Distilled water
1343	HALOBACTERIUM MEDIUM (DSMZ Medium 97)		Medium recipe at MediaDive	Name: HALOBACTERIUM MEDIUM (DSMZ Medium 97) Composition: NaCl 250.0 g/l Agar 20.0 g/l MgSO4 x 7 H2O 20.0 g/l Yeast extract 10.0 g/l Casamino acids 7.5 g/l Na3-citrate 3.0 g/l KCl 2.0 g/l FeSO4 x 7 H2O 0.05 g/l MnSO4 x H2O 0.0002 g/l Distilled water

Culture temp

@ref	Growth	Type	Temperature (°C)
1343	positive	growth	37
67770	positive	growth	37

Physiology and metabolism

Spore formation

@ref	Spore formation	Confidence
125439		98.272

Observation

67770

Observationquinones: MK-8, MK-8(H₂)

Pathway annotation

Computationally determined by

@ref	pathway	enzyme coverage	annotated reactions
66794	formaldehyde oxidation	100	3 of 3
66794	denitrification	100	2 of 2
66794	UDP-GlcNAc biosynthesis	100	3 of 3
66794	suberin monomers biosynthesis	100	2 of 2
66794	adipate degradation	100	2 of 2
66794	aerobactin biosynthesis	100	1 of 1
66794	cardiolipin biosynthesis	100	7 of 7
66794	coenzyme A metabolism	100	4 of 4
66794	anapleurotic synthesis of oxalacetate	100	1 of 1
66794	methylglyoxal degradation	100	5 of 5
66794	folate polyglutamylation	100	1 of 1
66794	molybdenum cofactor biosynthesis	100	9 of 9
66794	proline metabolism	90.91	10 of 11
66794	threonine metabolism	90	9 of 10
66794	Entner Doudoroff pathway	90	9 of 10
66794	starch degradation	90	9 of 10
66794	chorismate metabolism	88.89	8 of 9
66794	CO2 fixation in Crenarchaeota	88.89	8 of 9
66794	isoleucine metabolism	87.5	7 of 8
66794	palmitate biosynthesis	86.36	19 of 22
66794	vitamin B1 metabolism	84.62	11 of 13
66794	phenylalanine metabolism	84.62	11 of 13
66794	alanine metabolism	82.76	24 of 29
66794	flavin biosynthesis	80	12 of 15
66794	pyrimidine metabolism	80	36 of 45
66794	ethylmalonyl-CoA pathway	80	4 of 5
66794	propionate fermentation	80	8 of 10
66794	phenylacetate degradation (aerobic)	80	4 of 5
66794	factor 420 biosynthesis	80	4 of 5
66794	photosynthesis	78.57	11 of 14
66794	glutamate and glutamine metabolism	78.57	22 of 28
66794	heme metabolism	78.57	11 of 14
66794	valine metabolism	77.78	7 of 9
66794	aspartate and asparagine metabolism	77.78	7 of 9
66794	allantoin degradation	77.78	7 of 9
66794	glycolysis	76.47	13 of 17
66794	glycogen biosynthesis	75	3 of 4
66794	acetate fermentation	75	3 of 4
66794	ketogluconate metabolism	75	6 of 8
66794	C4 and CAM-carbon fixation	75	6 of 8
66794	6-hydroxymethyl-dihydropterin diphosphate biosynthesis	75	6 of 8
66794	dTDPLrhamnose biosynthesis	75	6 of 8
66794	gluconeogenesis	75	6 of 8
66794	tryptophan metabolism	73.68	28 of 38
66794	purine metabolism	73.4	69 of 94
66794	NAD metabolism	72.22	13 of 18
66794	citric acid cycle	71.43	10 of 14
66794	tetrahydrofolate metabolism	71.43	10 of 14
66794	ubiquinone biosynthesis	71.43	5 of 7
66794	leucine metabolism	69.23	9 of 13
66794	methionine metabolism	69.23	18 of 26
66794	non-pathway related	68.42	26 of 38
66794	vitamin B12 metabolism	67.65	23 of 34
66794	acetoin degradation	66.67	2 of 3
66794	glycolate and glyoxylate degradation	66.67	4 of 6
66794	nitrate assimilation	66.67	6 of 9
66794	cyanate degradation	66.67	2 of 3
66794	enterobactin biosynthesis	66.67	2 of 3
66794	octane oxidation	66.67	2 of 3
66794	serine metabolism	66.67	6 of 9
66794	d-mannose degradation	66.67	6 of 9
66794	lysine metabolism	66.67	28 of 42
66794	L-lactaldehyde degradation	66.67	2 of 3
66794	oxidative phosphorylation	65.93	60 of 91
66794	lipid metabolism	64.52	20 of 31
66794	degradation of pentoses	64.29	18 of 28
66794	pentose phosphate pathway	63.64	7 of 11
66794	d-xylose degradation	63.64	7 of 11
66794	urea cycle	61.54	8 of 13
66794	cysteine metabolism	61.11	11 of 18
66794	degradation of sugar acids	60	15 of 25
66794	gallate degradation	60	3 of 5
66794	3-chlorocatechol degradation	60	3 of 5
66794	hydrogen production	60	3 of 5
66794	creatinine degradation	60	3 of 5
66794	vitamin K metabolism	60	3 of 5
66794	4-hydroxyphenylacetate degradation	60	6 of 10
66794	myo-inositol biosynthesis	60	6 of 10
66794	histidine metabolism	58.62	17 of 29
66794	arginine metabolism	58.33	14 of 24
66794	reductive acetyl coenzyme A pathway	57.14	4 of 7
66794	propanol degradation	57.14	4 of 7
66794	polyamine pathway	56.52	13 of 23
66794	degradation of sugar alcohols	56.25	9 of 16
66794	vitamin B6 metabolism	54.55	6 of 11
66794	cholesterol biosynthesis	54.55	6 of 11
66794	sulfate reduction	53.85	7 of 13
66794	kanosamine biosynthesis II	50	1 of 2
66794	CDP-diacylglycerol biosynthesis	50	1 of 2
66794	aminopropanol phosphate biosynthesis	50	1 of 2
66794	ribulose monophosphate pathway	50	1 of 2
66794	ascorbate metabolism	50	11 of 22
66794	carotenoid biosynthesis	50	11 of 22
66794	cis-vaccenate biosynthesis	50	1 of 2
66794	glutathione metabolism	50	7 of 14
66794	degradation of aromatic, nitrogen containing compounds	50	6 of 12
66794	selenocysteine biosynthesis	50	3 of 6
66794	glycine metabolism	50	5 of 10
66794	biotin biosynthesis	50	2 of 4
66794	tyrosine metabolism	50	7 of 14
66794	vitamin E metabolism	50	2 of 4
66794	butanoate fermentation	50	2 of 4
66794	quinate degradation	50	1 of 2
66794	ethanol fermentation	50	1 of 2
66794	phenol degradation	45	9 of 20
66794	degradation of hexoses	44.44	8 of 18
66794	androgen and estrogen metabolism	43.75	7 of 16
66794	mevalonate metabolism	42.86	3 of 7
66794	lipoate biosynthesis	40	2 of 5
66794	glycogen metabolism	40	2 of 5
66794	coenzyme M biosynthesis	40	4 of 10
66794	bacilysin biosynthesis	40	2 of 5
66794	arachidonic acid metabolism	38.89	7 of 18
66794	metabolism of disaccharids	36.36	4 of 11
66794	isoprenoid biosynthesis	34.62	9 of 26
66794	IAA biosynthesis	33.33	1 of 3
66794	methanogenesis from CO2	33.33	4 of 12
66794	acetyl CoA biosynthesis	33.33	1 of 3
66794	lipid A biosynthesis	33.33	3 of 9
66794	pantothenate biosynthesis	33.33	2 of 6
66794	(5R)-carbapenem carboxylate biosynthesis	33.33	1 of 3
66794	aclacinomycin biosynthesis	28.57	2 of 7
66794	benzoyl-CoA degradation	28.57	2 of 7
66794	dolichyl-diphosphooligosaccharide biosynthesis	27.27	3 of 11
66794	3-phenylpropionate degradation	26.67	4 of 15
66794	catecholamine biosynthesis	25	1 of 4
66794	sulfopterin metabolism	25	1 of 4
66794	CMP-KDO biosynthesis	25	1 of 4
66794	cyclohexanol degradation	25	1 of 4
66794	lactate fermentation	25	1 of 4
66794	ppGpp biosynthesis	25	1 of 4
66794	toluene degradation	25	1 of 4
66794	phosphatidylethanolamine bioynthesis	23.08	3 of 13
66794	4-hydroxymandelate degradation	22.22	2 of 9

Isolation, sampling and environmental information

Isolation source categories

Cat1	Cat2	Cat3
#Environmental	#Terrestrial	#Tidal flat
#Environmental	#Terrestrial	#Sediment

Isolation

@ref	Sample type	Geographic location
1343	bottom sediment, 1 m below surface	northern end of Dead Sea
67770	Sediment from the Dead Sea

Taxonmaps

69479

Global distribution of 16S sequence AB663383 (>99% sequence identity) for Haloferax from Microbeatlas

Aquatic Samples	7
Soil Samples	1
Animal Samples	0
Plant Samples	0
Total Samples	8

Interaction and safety

Risk assessment

@ref	Biosafety level	Biosafety level comment
1343	1	Risk group (German classification) According to TRBA 466

Sequence information

Genome sequences

@ref	Description	Assembly level	INSDC accession	BV-BRC accession	IMG accession	NCBI tax ID	Score
66792	ASM2568v1 assembly for Haloferax volcanii DS2	complete	GCA_000025685	309800.28	646564536	309800	98.22
66792	ASM33731v1 assembly for Haloferax volcanii DS2	contig	GCA_000337315	309800.29	2529293123	309800	55.18

16S sequences

@ref	Description	Accession	Length	NCBI tax ID
1343	Haloferax volcanii gene for 16S rRNA, complete sequence, strain: JCM 8879	AB663383	1473	2246
1343	Haloferax volcanii strain NCIMB 2012 16S ribosomal RNA gene, partial sequence	AY425724	1404	2246
67770	Halobacterium volcanii 16S ribosomal RNA	K00421	1472	2246

GC content

@ref	GC-content (mol%)	Method
1343	66.5
67770	64.9	thermal denaturation, midpoint method (Tm)
67770	63.4	thermal denaturation, midpoint method (Tm)

Genome-based predictions

Predictions

Predictions from Deep Learning for Genome Sequence Data. R package version 0.3.1 based on: ASM2568v1 assembly for Haloferax volcanii DS2
BV-BRC: 309800.28

@ref	Trait	Model	Prediction	Confidence in %	In training data
125439	oxygen_tolerance	BacteriaNetⓘ	facultative anaerobe	89.62	no
125439	gram_stain	BacteriaNetⓘ	negative	55.60	no
125439	motility	BacteriaNetⓘ	yes	50.85	no
125439	spore_formation	BacteriaNetⓘ	no	98.27	no

Predictions from bacterial phenotypic traits through improved machine learning using high-quality, curated datasets based on: Haloferax volcanii DS2 DS2
NCBI: GCA_000025685.1

@ref	Trait	Model	Prediction	Confidence in %	In training data
125438	gram-positive	gram-positiveⓘ	no	77.53	no
125438	anaerobic	anaerobicⓘ	no	78.96	no
125438	aerobic	aerobicⓘ	yes	81.34	no
125438	spore-forming	spore-formingⓘ	no	81.53	no
125438	thermophilic	thermophileⓘ	no	78.83	yes
125438	flagellated	motile2+ⓘ	no	84.00	no

Literature

Topic	Title	Authors	Journal	DOI	Year
Phylogeny	Lipidomic chemotaxonomy aligned with phylogeny of Halobacteria.	Yao W, Zhang W, He W, Xiao W, Chen Y, Zhu Y, Zheng F, Zhang C.	Front Microbiol	10.3389/fmicb.2023.1297600	2023
	Archaeal Persisters: Persister Cell Formation as a Stress Response in Haloferax volcanii.	Megaw J, Gilmore BF.	Front Microbiol	10.3389/fmicb.2017.01589	2017
Enzymology	Crystal structures of a halophilic archaeal malate synthase from Haloferax volcanii and comparisons with isoforms A and G.	Bracken CD, Neighbor AM, Lamlenn KK, Thomas GC, Schubert HL, Whitby FG, Howard BR.	BMC Struct Biol	10.1186/1472-6807-11-23	2011
Metabolism	Archaeal ubiquitin-like SAMP3 is isopeptide-linked to proteins via a UbaA-dependent mechanism.	Miranda HV, Antelmann H, Hepowit N, Chavarria NE, Krause DJ, Pritz JR, Basell K, Becher D, Humbard MA, Brocchieri L, Maupin-Furlow JA.	Mol Cell Proteomics	10.1074/mcp.m113.029652	2014
Metabolism	Survey of archaeal diversity reveals an abundance of halophilic Archaea in a low-salt, sulfide- and sulfur-rich spring.	Elshahed MS, Najar FZ, Roe BA, Oren A, Dewers TA, Krumholz LR.	Appl Environ Microbiol	10.1128/aem.70.4.2230-2239.2004	2004
Genetics	Genomic re-sequencing reveals mutational divergence across genetically engineered strains of model archaea.	Soborowski AL, Hackley RK, Hwang S, Zhou G, Dulmage KA, Schonheit P, Daniels C, Bisson-Filho AW, Marchfelder A, Maupin-Furlow JA, Allers T, Schmid AK.	mSystems	10.1128/msystems.01084-24	2025
	Similar mutation rates but different mutation spectra in moderate and extremely halophilic archaea.	Kucukyildirim S, Ozdemirel HO, Lynch M.	G3 (Bethesda)	10.1093/g3journal/jkac303	2023
Metabolism	Protein Splicing Activity of the Haloferax volcanii PolB-c Intein Is Sensitive to Homing Endonuclease Domain Mutations.	Robinzon S, Cawood AR, Ruiz MA, Gophna U, Altman-Price N, Mills KV.	Biochemistry	10.1021/acs.biochem.0c00512	2020
Genetics	Estimation of the Genome-Wide Mutation Rate and Spectrum in the Archaeal Species Haloferax volcanii.	Kucukyildirim S, Behringer M, Williams EM, Doak TG, Lynch M.	Genetics	10.1534/genetics.120.303299	2020
Metabolism	Assays for ubiquitin-like protein ligation and proteasome function in archaea.	Fu X, Adams Z, Maupin-Furlow J.	Methods Enzymol	10.1016/bs.mie.2018.12.036	2019
Genetics	Deconstruction of archaeal genome depict strategic consensus in core pathways coding sequence assembly.	Pal A, Banerjee R, Mondal UK, Mukhopadhyay S, Bothra AK.	PLoS One	10.1371/journal.pone.0118245	2015
Enzymology	Enzymatic and genetic characterization of lignin depolymerization by Streptomyces sp. S6 isolated from a tropical environment.	Riyadi FA, Tahir AA, Yusof N, Sabri NSA, Noor MJMM, Akhir FNMD, Othman N, Zakaria Z, Hara H.	Sci Rep	10.1038/s41598-020-64817-4	2020
Genetics	Complete genome sequence of Bacillus velezensis ZY-1-1 reveals the genetic basis for its hemicellulosic/cellulosic substrate-inducible xylanase and cellulase activities.	Zhang ZY, Raza MF, Zheng Z, Zhang X, Dong X, Zhang H.	3 Biotech	10.1007/s13205-018-1490-x	2018
Genetics	The complete genome sequence of Haloferax volcanii DS2, a model archaeon.	Hartman AL, Norais C, Badger JH, Delmas S, Haldenby S, Madupu R, Robinson J, Khouri H, Ren Q, Lowe TM, Maupin-Furlow J, Pohlschroder M, Daniels C, Pfeiffer F, Allers T, Eisen JA.	PLoS One	10.1371/journal.pone.0009605	2010
	Synthetic archaeosome vaccines containing triglycosylarchaeols can provide additive and long-lasting immune responses that are enhanced by archaetidylserine.	Sprott GD, Yeung A, Dicaire CJ, Yu SH, Whitfield DM.	Archaea	10.1155/2012/513231	2012
Metabolism	Amino acid substitutions in cold-adapted proteins from Halorubrum lacusprofundi, an extremely halophilic microbe from antarctica.	DasSarma S, Capes MD, Karan R, DasSarma P.	PLoS One	10.1371/journal.pone.0058587	2013
Genetics	Genomic Methods and Microbiological Technologies for Profiling Novel and Extreme Environments for the Extreme Microbiome Project (XMP).	Tighe S, Afshinnekoo E, Rock TM, McGrath K, Alexander N, McIntyre A, Ahsanuddin S, Bezdan D, Green SJ, Joye S, Stewart Johnson S, Baldwin DA, Bivens N, Ajami N, Carmical JR, Herriott IC, Colwell R, Donia M, Foox J, Greenfield N, Hunter T, Hoffman J, Hyman J, Jorgensen E, Krawczyk D, Lee J, Levy S, Garcia-Reyero N, Settles M, Thomas K, Gomez F, Schriml L, Kyrpides N, Zaikova E, Penterman J, Mason CE.	J Biomol Tech	10.7171/jbt.17-2801-004	2017
Metabolism	An archaeal immune system can detect multiple protospacer adjacent motifs (PAMs) to target invader DNA.	Fischer S, Maier LK, Stoll B, Brendel J, Fischer E, Pfeiffer F, Dyall-Smith M, Marchfelder A.	J Biol Chem	10.1074/jbc.m112.377002	2012
Phylogeny	Quantifying homologous replacement of loci between haloarchaeal species.	Williams D, Gogarten JP, Papke RT.	Genome Biol Evol	10.1093/gbe/evs098	2012
Phylogeny	Phylogenetic analyses of some extremely halophilic archaea isolated from Dead Sea water, determined on the basis of their 16S rRNA sequences.	Arahal DR, Dewhirst FE, Paster BJ, Volcani BE, Ventosa A.	Appl Environ Microbiol	10.1128/aem.62.10.3779-3786.1996	1996
Enzymology	A novel enzymatic pathway leading to 1-methylinosine modification in Haloferax volcanii tRNA.	Grosjean H, Constantinesco F, Foiret D, Benachenhou N.	Nucleic Acids Res	10.1093/nar/23.21.4312	1995
Phylogeny	PH1: an archaeovirus of Haloarcula hispanica related to SH1 and HHIV-2.	Porter K, Tang SL, Chen CP, Chiang PW, Hong MJ, Dyall-Smith M.	Archaea	10.1155/2013/456318	2013
	Phylogenetic analysis of nonthermophilic members of the kingdom crenarchaeota and their diversity and abundance in soils	Buckley DH, Graber JR, Schmidt TM.	Appl Environ Microbiol	10.1128/aem.64.11.4333-4339.1998	1998
	Viral contribution to dissolved DNA in the marine environment as determined by differential centrifugation and kingdom probing.	Jiang SC, Paul JH.	Appl Environ Microbiol	10.1128/aem.61.1.317-325.1995	1995
	Compilation of 5S rRNA and 5S rRNA gene sequences.	Specht T, Wolters J, Erdmann VA.	Nucleic Acids Res	10.1093/nar/18.suppl.2215	1990
Metabolism	Deciphering the Translation Initiation Factor 5A Modification Pathway in Halophilic Archaea.	Prunetti L, Graf M, Blaby IK, Peil L, Makkay AM, Starosta AL, Papke RT, Oshima T, Wilson DN, de Crecy-Lagard V.	Archaea	10.1155/2016/7316725	2016
Metabolism	Methanogen prevalence throughout the gastrointestinal tract of pre-weaned dairy calves.	Zhou M, Chen Y, Griebel PJ, Guan le L.	Gut Microbes	10.4161/19490976.2014.969649	2014
Enzymology	Detection and cultivation of soil verrucomicrobia.	Sangwan P, Kovac S, Davis KE, Sait M, Janssen PH.	Appl Environ Microbiol	10.1128/aem.71.12.8402-8410.2005	2005
Pathogenicity	Generalist hydrocarbon-degrading bacterial communities in the oil-polluted water column of the North Sea.	Chronopoulou PM, Sanni GO, Silas-Olu DI, van der Meer JR, Timmis KN, Brussaard CP, McGenity TJ.	Microb Biotechnol	10.1111/1751-7915.12176	2015
Enzymology	Effect of pH on isolation and distribution of members of subdivision 1 of the phylum Acidobacteria occurring in soil.	Sait M, Davis KE, Janssen PH.	Appl Environ Microbiol	10.1128/aem.72.3.1852-1857.2006	2006
Enzymology	Molecular cloning and sequencing of the gene for a halophilic alkaline serine protease (halolysin) from an unidentified halophilic archaea strain (172P1) and expression of the gene in Haloferax volcanii.	Kamekura M, Seno Y, Holmes ML, Dyall-Smith ML.	J Bacteriol	10.1128/jb.174.3.736-742.1992	1992
Stress	Dynamic acetylation of a conserved lysine impacts glycerol kinase activity and abundance in the haloarchaeon Haloferax volcanii.	Sanchez KM, Addagarla M, Judd H, Wang X, Maupin-Furlow J.	J Biol Chem	10.1016/j.jbc.2025.110960	2025
	A colorful new reporter system to evaluate gene expression in the archaeon Haloferax volcanii.	Frecha SD, Gimenez MI, Paggi RA, Castro RE, Cerletti M.	Extremophiles	10.1007/s00792-025-01391-5	2025
	Rapid rewiring of an archaeal transcription factor function via flexible cis-trans interactions.	Pastor MM, Darnell CL, Vreugdenhil A, Schmid AK.	Mol Biol Cell	10.1091/mbc.e24-11-0505	2025
	Cell division protein CdpA organises and anchors the midcell ring in haloarchaea.	Liao Y, Shinde VD, Hu D, Xu Z, Soderstrom B, Michie KA, Duggin IG.	Nat Commun	10.1038/s41467-025-60079-8	2025
Genetics	Complete genome sequence of the halophilic archaeon Haloferax volcanii PC0224, isolated from a solar saltern in Thailand.	Phatcharaharikarn M, Ruangsuj P, Songngamsuk T, Santaweesuk P, Tangwattanachuleeporn M, Srisucharitpanit K, Wongchitrat P, Yasawong M.	BMC Genom Data	10.1186/s12863-025-01353-y	2025
Metabolism	Functional Role and Mutational Analysis of the Phytoene Synthase from the Halophilic Euryarchaeon Haloferax volcanii in Bacterioruberin Biosynthesis.	Lin Y, Chen M, Jiang W, Zhang L, Shen L, Bai Y.	J Agric Food Chem	10.1021/acs.jafc.4c08894	2025
	Biogenesis, function and evolution of the archaeal S-layer.	Sivabalasarma S, van Wolferen M, Albers SV, Charles-Orszag A.	Curr Opin Cell Biol	10.1016/j.ceb.2025.102534	2025
	Elucidating the Role and Mechanism of Lycopene beta-Cyclase from Haloarcula marismortui through Functional Characterization and Targeted Mutagenesis.	Zhang L, Chen C, He Y, Cao M, Lin Y, Huang K, Zhang H, Wu C, Chen M, Shen L.	J Agric Food Chem	10.1021/acs.jafc.5c02985	2025
	Practical laboratory class to assess gene silencing using CRISPR interference (CRISPRi) technology in the archaeon Haloferax volcanii.	Paggi RA, Ferrari MC, Cerletti M, Gimenez MI, Schwarz TS, Marchfelder A, De Castro RE.	Biochem Mol Biol Educ	10.1002/bmb.21872	2025
	Quadruplexes with a grain of salt: influence of cation type and concentration on DNA G4 stability.	Cucchiarini A, Kledus F, Luo Y, Brazda V, Mergny JL.	Eur Biophys J	10.1007/s00249-025-01772-w	2025
Enzymology	A systematic analysis of affinity tags in the haloarchaeal expression system, Haloferax volcanii for protein purification.	Karan R, Renn D, Allers T, Rueping M.	Front Microbiol	10.3389/fmicb.2024.1403623	2024
Enzymology	A vector system for single and tandem expression of cloned genes and multi-colour fluorescent tagging in Haloferax volcanii.	Ithurbide S, de Silva RT, Brown HJ, Shinde V, Duggin IG.	Microbiology (Reading)	10.1099/mic.0.001461	2024
	Identification and characterization of a novel type of ketohexokinase from the haloarchaeon Haloferax volcanii.	Ortjohann M, Schonheit P.	FEMS Microbiol Lett	10.1093/femsle/fnae026	2024
	Evolutionary insights into provirus-encoded CRISPR-Cas systems in halophilic archaea.	Naki D, Gophna U.	Microlife	10.1093/femsml/uqaf033	2025
	Revisiting synthetic lethality of Gcn5-related N-acetyltransferase (GNAT) family mutations in Haloferax volcanii.	Weber KR, Novillo B, Maupin-Furlow JA.	Microbiol Spectr	10.1128/spectrum.01229-25	2025
Genetics	Genome-wide ribonucleotide detection in Archaea.	Moalic Y, Reveil M, Kundnani DL, Balachander S, Yang T, Gombolay A, Ranjbarian F, Brizard R, Durand P, Myllykallio H, Jebbar M, Hofer A, Storici F, Henneke G.	Nucleic Acids Res	10.1093/nar/gkaf1231	2025
	Investigation of the global translational response to oxidative stress in the model archaeon Haloferax volcanii reveals untranslated small RNAs with ribosome occupancy.	Dallon E, Moran HM, Chidambaran SR, Kian A, Huang BYH, Fried SD, DiRuggiero J.	mSphere	10.1128/msphere.00343-25	2025
	Proteins containing photosynthetic reaction centre domains modulate FtsZ-based archaeal cell division.	Nussbaum P, Kureisaite-Ciziene D, Bellini D, van der Does C, Kojic M, Taib N, Yeates A, Tourte M, Gribaldo S, Loose M, Lowe J, Albers SV.	Nat Microbiol	10.1038/s41564-024-01600-5	2024
	Widespread photosynthesis reaction centre barrel proteins are necessary for haloarchaeal cell division.	Zhao S, Makarova KS, Zheng W, Zhan L, Wan Q, Liu Y, Gong H, Krupovic M, Lutkenhaus J, Chen X, Koonin EV, Du S.	Nat Microbiol	10.1038/s41564-024-01615-y	2024
	Characterization of archaeal promoters using explainable and web-based CNN model.	Shujaat M, Mao SQ.	BMC Genomics	10.1186/s12864-025-12121-8	2025
Biotechnology	Haloferax volcanii: a versatile model for studying archaeal biology.	Pohlschroder M, Schulze S, Pfeiffer F, Hong Y.	J Bacteriol	10.1128/jb.00062-25	2025
	CRISPR-Cas induced self-targeting identifies key players in archaeal microhomology-mediated end joining.	Sailer AL, Wortz J, Smith V, Stachler AE, Blau F, Daratha M, Maier LK, Allers T, Marchfelder A.	Microlife	10.1093/femsml/uqaf015	2025
	Archaeal type IV pili stabilize Haloferax volcanii biofilms in flow.	Odermatt PD, Nussbaum P, Monnappa S, Tala L, Li Z, Sivabalasarma S, Albers SV, Persat A.	Curr Biol	10.1016/j.cub.2023.06.055	2023
Metabolism	GNAT family Pat2 is required for long-term survival on glycerol and catalyzes lysine acetylation of glycerol kinase in hypersaline-adapted archaea.	Judd HN, Sanchez KM, Dublino LS, Zhang GJ, Yu D, Gal D, Couto-Rodriguez RL, Wang X, Maupin-Furlow JA.	mBio	10.1128/mbio.02514-25	2025
	Quorum sensing mediates morphology and motility transitions in the model archaeon Haloferax volcanii.	Chatterjee P, Consoli CE, Schiller H, Winter KK, McCallum ME, Schulze S, Pohlschroder M.	mBio	10.1128/mbio.00906-25	2025
Phylogeny	Taxonomic Reframe of Some Species of the Genera Haloferax and Halobellus.	Quadri SR, Jin P, Wang K, Qiao H, Dhulappa A, Luo ZH, Wang S, Narsing Rao MP.	Curr Microbiol	10.1007/s00284-024-03695-9	2024
Biotechnology	Comparative genomics of the highly halophilic Haloferacaceae.	Griffiths DB, Tiwari RP, Murphy DV, Scott C.	Sci Rep	10.1038/s41598-024-78438-8	2024
	Effects of chaotropic salts on global proteome stability in halophilic archaea: Implications for life signatures on Mars.	Carre L, Gonzalez D, Girard E, Franzetti B.	Environ Microbiol	10.1111/1462-2920.16451	2023
	iPro-MP: a BERT-based model to predict multiple prokaryotic promoters.	Su W, Yang Y, Zhao Y, Yuan S, Xie X, Hao Y, Zhang H, Ye D, Lyu H, Lin H.	Genome Biol	10.1186/s13059-025-03819-9	2025
	Internal in-frame translation generates Cas11b, which is important for effective interference in an archaeal CRISPR-Cas system.	Sailer AL, Brendel J, Chernev A, Konig S, Bischler T, Grafenhan T, Urlaub H, Gophna U, Marchfelder A.	Front Microbiol	10.3389/fmicb.2025.1543464	2025
	MinD2 modulates cell shape and motility in the archaeon Haloferax volcanii.	Patro M, Grunberger F, Sivabalasarma S, Gfrerer S, Rodriguez-Franco M, Nussbaum P, Grohmann D, Ithurbide S, Albers SV.	Front Microbiol	10.3389/fmicb.2024.1474570	2024
Metabolism	Biochemical properties of glycerol kinase from the hypersaline-adapted archaeon Haloferax volcanii.	Sanchez KM, Maupin-Furlow JA.	Appl Environ Microbiol	10.1128/aem.00886-25	2025
	MinD proteins regulate CetZ1 localization in Haloferax volcanii.	Brown HJ, Duggin IG.	Front Microbiol	10.3389/fmicb.2024.1474697	2024
Biotechnology	DPANN symbiont of Haloferax volcanii accelerates xylan degradation by the non-host haloarchaeon Halorhabdus sp.	Reva ON, La Cono V, Marturano L, Crisafi F, Smedile F, Mudaliyar M, Ghosal D, Selivanova EA, Ignatenko ME, Ferrer M, Fernandez-Lopez L, Krupovic M, Yakimov MM.	iScience	10.1016/j.isci.2025.111749	2025
	Provirus deletion from Haloferax volcanii affects motility, stress resistance, and CRISPR RNA expression.	Di Cianni N, Bolsinger S, Brendel J, Raabe M, Konig S, Mitchell L, Bischler T, Grafenhan T, Read C, Erdmann S, Allers T, Walther P, Urlaub H, Dyall-Smith M, Pfeiffer F, Marchfelder A.	Microlife	10.1093/femsml/uqaf008	2025
	Molecular adaptations specific to extreme halophilic archaea could promote high perchlorate tolerance.	Diaz-Rullo J, Gonzalez-Pastor JE.	Appl Environ Microbiol	10.1128/aem.00512-25	2025
	The C-terminal region of phytoene synthase is a key element to control carotenoid biosynthesis in the haloarchaeon Haloferax volcanii.	Cerletti M, Rabino A, Paggi RA, Ferrari C, Poetsch A, Savilahti H, Kiljunen S, De Castro RE.	Biochem J	10.1042/bcj20220403	2022
Enzymology	Functional expression of an antimicrobial peptide, belonging to halocin C8 family, from Natrinema sp. RNS21 in Escherichia coli.	Ri CH, Li SR, Paek CI, Kim YS.	Extremophiles	10.1007/s00792-023-01308-0	2023
Proteome	Iron starvation results in up-regulation of a probable Haloferax volcanii siderophore transporter.	Sailer AL, Jevtic Z, Stoll B, Wortz J, Sharma K, Urlaub H, Dyall-Smith M, Pfeiffer F, Marchfelder A, Lenz C.	Front Microbiol	10.3389/fmicb.2024.1422844	2024
Enzymology	Pharmaceutical applications of halophilic enzymes.	Yavari-Bafghi M, Amoozegar MA.	Heliyon	10.1016/j.heliyon.2025.e42754	2025
	CRISPR Interference as a Tool to Repress Gene Expression in Haloferax volcanii.	Schwarz TS, Schreiber SS, Marchfelder A.	Methods Mol Biol	10.1007/978-1-0716-2445-6_4	2022
	Small RNA-Sequencing Library Preparation for the Halophilic Archaeon Haloferax volcanii.	Gelsinger DR, DiRuggiero J.	Methods Mol Biol	10.1007/978-1-0716-2445-6_15	2022
	In Vivo Protein Cross-Linking and Coimmunoprecipitation in Haloferax volcanii.	Paggi RA, De Castro RE, Cerletti M.	Methods Mol Biol	10.1007/978-1-0716-2445-6_19	2022
	Metal nanoparticles Biosynthesis Using the Halophilic Archaeon Haloferax volcanii.	Costa MI, Gimenez MI.	Methods Mol Biol	10.1007/978-1-0716-2445-6_22	2022
	Immersed Liquid Biofilm and Honeycomb Pattern Formations in Haloferax volcanii.	Mutan Z, Schiller H, Schulze S, Pohlschroder M.	Methods Mol Biol	10.1007/978-1-0716-2445-6_26	2022
	Nanopore-based RNA sequencing deciphers the formation, processing, and modification steps of rRNA intermediates in archaea.	Grunberger F, Juttner M, Knuppel R, Ferreira-Cerca S, Grohmann D.	RNA	10.1261/rna.079636.123	2023
Proteome	Proteome Turnover Analysis in Haloferax volcanii by a Heavy Isotope Multilabeling Approach.	Paggi RA, Albaum SP, Poetsch A, Cerletti M.	Methods Mol Biol	10.1007/978-1-0716-2445-6_17	2022
	Accessible and Insightful Scientific Learning Experiences Using the Microorganism Haloferax volcanii.	Schiller H, Young C, Schulze S, Pohlschroder M.	Methods Mol Biol	10.1007/978-1-0716-2445-6_34	2022
	Archaeal Tubulin-like Proteins Modify Cell Shape in Haloferax volcanii during Early Biofilm Development.	Cooper A, Makkay AM, Papke RT.	Genes (Basel)	10.3390/genes14101861	2023
	Conversion of Ribosome-Protected mRNA to DNA and Deep Sequencing for Ribosome Profiling in Haloferax volcanii.	Gelsinger DR, Dallon E, DiRuggiero J.	Methods Mol Biol	10.1007/978-1-0716-2445-6_14	2022
	BrdU Incorporation and Labeling of Nascent DNA to Investigate Archaeal Replication Using Super-Resolution Imaging.	Lestini R, Collien Y, Olivier D, Olivier N, Myllykallio H.	Methods Mol Biol	10.1007/978-1-0716-2445-6_29	2022
	Identification of SepF in Streptococcus suis involving cell division.	Gao T, Li T, Zhu J, Zheng L, Chen M, Liu W, Yang K, Zhang T, Yuan F, Liu Z, Guo R, Li C, Wu Q, Tian Y, Zhou R, Zhou D.	BMC Microbiol	10.1186/s12866-025-03919-3	2025
	Carotenoids from Haloarchaea: Extraction, Fractionation, and Characterization.	Churio MS, Cerletti M, De Castro RE.	Methods Mol Biol	10.1007/978-1-0716-2445-6_21	2022
	C(P)XCG Proteins of Haloferax volcanii with Predicted Zinc Finger Domains: The Majority Bind Zinc, but Several Do Not.	Uresin D, Schulte J, Morgner N, Soppa J.	Int J Mol Sci	10.3390/ijms25137166	2024
	Non-radioactive In Vivo Labeling of RNA with 4-Thiouracil.	Braun C, Knuppel R, Perez-Fernandez J, Ferreira-Cerca S.	Methods Mol Biol	10.1007/978-1-0716-2501-9_12	2022
	Uncovering the prevalence, key biogenesis enzymes, and biological significance of archaeal lipoproteins.	Hong Y, Makarova KS, Garcia AA, Xu R, Pfeiffer F, Welander PV, Pohlschroder M.	Nat Commun	10.1038/s41467-025-63625-6	2025
Proteome	Exploring protein N-glycosylation in ammonia-oxidizing Nitrososphaerota archaea through glycoproteomic analysis.	Nakagawa S, Yagi H, Suyama T, Shimamura S, Yanaka S, Yagi-Utsumi M, Kato S, Ohkuma M, Kato K, Takai K.	mBio	10.1128/mbio.03859-24	2025
Proteome	Proteomic Sample Preparation and Data Analysis in Line with the Archaeal Proteome Project.	Schulze S, Pohlschroder M.	Methods Mol Biol	10.1007/978-1-0716-2445-6_18	2022
Phylogeny	DUF99 family proteins are novel endonucleases that cleave deoxyuridine on DNA substrates.	Li J, Xia R, Huang WC, Gu J, Li M.	J Biol Chem	10.1016/j.jbc.2024.107901	2024
	Methods to Analyze Motility in Eury- and Crenarchaea.	Patro M, van Wolferen M, Ye X, Albers SV, Quax TEF.	Methods Mol Biol	10.1007/978-1-0716-2445-6_25	2022
Enzymology	Isolation, Purification, and Characterization of Membrane Vesicles from Haloarchaea.	Mills J, Erdmann S.	Methods Mol Biol	10.1007/978-1-0716-2445-6_30	2022
	A sweet new set of inducible and constitutive promoters in Haloferax volcanii.	Rados T, Andre K, Cerletti M, Bisson A.	Front Microbiol	10.3389/fmicb.2023.1204876	2023
	The chromatin landscape of the euryarchaeon Haloferax volcanii.	Marinov GK, Bagdatli ST, Wu T, He C, Kundaje A, Greenleaf WJ.	Genome Biol	10.1186/s13059-023-03095-5	2023
	Differential Translation Activity Analysis Using Bioorthogonal Noncanonical Amino Acid Tagging (BONCAT) in Archaea.	Kern M, Ferreira-Cerca S.	Methods Mol Biol	10.1007/978-1-0716-2501-9_14	2022
	Archaea produce peptidoglycan hydrolases that kill bacteria	Strock R, Soo V, Misson P, Roumelioti G, Shliaha P, Hocher A, Warnecke T.	PLoS Biol		2025
	Advancing archaeal research through FAIR resource and data sharing, and inclusive community building.	Ithurbide S, Buan N, Schulze S.	Commun Biol	10.1038/s42003-025-07962-8	2025
	Discovery of a novel transcriptional regulator of sugar catabolism in archaea.	Johnsen U, Ortjohann M, Reinhardt A, Turner JM, Stratton C, Weber KR, Sanchez KM, Maupin-Furlow J, Davies C, Schonheit P.	Mol Microbiol	10.1111/mmi.15114	2023
	Intermolecular Gene Conversion for the Equalization of Genome Copies in the Polyploid Haloarchaeon Haloferax volcanii: Identification of Important Proteins.	Ozer H, Wasser D, Sandner L, Soppa J.	Genes (Basel)	10.3390/genes15070861	2024
	An RNA ligase partner for the prokaryotic protein-only RNase P: insights into the functional diversity of RNase P from genome mining.	Seshadri R, Gopalan V.	mBio	10.1128/mbio.00449-25	2025
	Wide Diversity and Complex Evolution of M42 Aminopeptidases With Contrasted Functional Properties in Archaea.	Chagny E, Taib N, Fenel D, Girard E, Gribaldo S, Flament D, Franzetti B.	Mol Biol Evol	10.1093/molbev/msaf233	2025
Metabolism	TbsP and TrmB jointly regulate gapII to influence cell development phenotypes in the archaeon Haloferax volcanii.	Hackley RK, Hwang S, Herb JT, Bhanap P, Lam K, Vreugdenhil A, Darnell CL, Pastor MM, Martin JH, Maupin-Furlow JA, Schmid AK.	Mol Microbiol	10.1111/mmi.15225	2024
	Deciphering transcript architectural complexity in bacteria and archaea.	Mattick JSA, Bromley RE, Watson KJ, Adkins RS, Holt CI, Lebov JF, Sparklin BC, Tyson TS, Rasko DA, Dunning Hotopp JC.	mBio	10.1128/mbio.02359-24	2024
Phylogeny	HaloClass: Salt-Tolerant Protein Classification with Protein Language Models.	Narang K, Nath A, Hemstrom W, Chu SKS.	Protein J	10.1007/s10930-024-10236-7	2024
Phylogeny	Ploidy levels in diverse picocyanobacteria from the Baltic Sea.	Weissenbach J, Aguilera A, Bas Conn L, Pinhassi J, Legrand C, Farnelid H.	Environ Microbiol Rep	10.1111/1758-2229.70005	2024
	Sugar alcohol degradation in Archaea: uptake and degradation of mannitol and sorbitol in Haloarcula hispanica.	Ortjohann M, Schonheit P.	Extremophiles	10.1007/s00792-024-01365-z	2024
Genetics	Archaeal DNA replication initiation: bridging LUCA's legacy and modern mechanisms.	Dulermo R.	Front Microbiol	10.3389/fmicb.2025.1561973	2025
	Purification of micrococcal nuclease for use in ribosomal profiling of high-salinity extremophiles.	Gregorova P, Isada M, DiRuggiero J, Sarin LP.	J Biol Chem	10.1016/j.jbc.2024.108020	2025
	Distinct Patterns of Antibiotic Sensitivities in Ammonia-Oxidising Archaea.	Klein T, Hodgskiss LH, Dreer M, Murrell JC, Hutchings MI, Schleper C, Lehtovirta-Morley LE.	Environ Microbiol	10.1111/1462-2920.70063	2025
	Genetic identification of acetyl-CoA synthetases involved in acetate activation in Haloferax mediterranei.	Mitra R, Xu Y, Lin L, Guo J, Xu T, Zhou M, Guo F, Li H, Xiang H, Han J.	Appl Environ Microbiol	10.1128/aem.01843-24	2025
	"Influence of plasmids, selection markers and auxotrophic mutations on Haloferax volcanii cell shape plasticity".	Patro M, Duggin IG, Albers SV, Ithurbide S.	Front Microbiol	10.3389/fmicb.2023.1270665	2023
	Protective Effects of Halite to Vacuum and Vacuum-Ultraviolet Radiation: A Potential Scenario During a Young Sun Superflare.	Abrevaya XC, Galante D, Tribelli PM, Oppezzo OJ, Nobrega F, Araujo GG, Rodrigues F, Odert P, Leitzinger M, Ricardi MM, Varela ME, Gallo T, Sanz-Forcada J, Ribas I, Porto de Mello GF, Rodler F, Cerini MF, Hanslmeier A, Horvath JE.	Astrobiology	10.1089/ast.2022.0016	2023
	Asgard Arf GTPases can act as membrane-associating molecular switches with the potential to function in organelle biogenesis.	Zhu J, Xie R, Ren Q, Zhou J, Chen C, Xie MX, Zhou Y, Zhang Y, Liu N, Wang J, Zhang Z, Liu X, Yan W, Gong Q, Dong L, Zhu J, Wang F, Xie Z.	Nat Commun	10.1038/s41467-025-57902-7	2025
	Rhomboid proteases: key players at the cell surface within haloarchaea.	Costa MI, Cerletti M, Paggi RA, Frecha SD, Zoratti V, Latorre LL, De Castro RE, Gimenez MI.	Front Microbiol	10.3389/fmicb.2025.1547649	2025
	Biological functions, genetic and biochemical characterization, and NMR structure determination of the small zinc finger protein HVO_2753 from Haloferax volcanii.	Zahn S, Kubatova N, Pyper DJ, Cassidy L, Saxena K, Tholey A, Schwalbe H, Soppa J.	FEBS J	10.1111/febs.15559	2021
	Identification of acetylated diether lipids in halophilic Archaea.	Kropp C, Lipp J, Schmidt AL, Seisenberger C, Linde M, Hinrichs KU, Babinger P.	Microbiologyopen	10.1002/mbo3.1299	2022
	Ultrastructure of Serratia liquefaciens Grown at 7 mbar Under Simulated Martian Conditions.	Schuerger AC, Kelley KL.	Microorganisms	10.3390/microorganisms13112466	2025
	Involvement of ArlI, ArlJ, and CirA in archaeal type IV pilin-mediated motility regulation.	Chatterjee P, Garcia MA, Cote JA, Yun K, Legerme GP, Habib R, Tripepi M, Young C, Kulp D, Dyall-Smith M, Pohlschroder M.	J Bacteriol	10.1128/jb.00089-24	2024
Metabolism	Synthesis, characterization and kinetic study of silver and gold nanoparticles produced by the archaeon Haloferax volcanii.	Costa MI, Alvarez-Cerimedo MS, Urquiza D, Ayude MA, Hoppe CE, Fasce DP, De Castro RE, Gimenez MI.	J Appl Microbiol	10.1111/jam.14726	2020
	A Twist to the Kirby-Bauer Disk Diffusion Susceptibility Test: an Accessible Laboratory Experiment Comparing Haloferax volcanii and Escherichia coli Antibiotic Susceptibility to Highlight the Unique Cell Biology of Archaea.	Schiller H, Young C, Schulze S, Tripepi M, Pohlschroder M.	J Microbiol Biol Educ	10.1128/jmbe.00234-21	2022
	Proteolysis at the Archaeal Membrane: Advances on the Biological Function and Natural Targets of Membrane-Localized Proteases in Haloferax volcanii.	De Castro RE, Gimenez MI, Cerletti M, Paggi RA, Costa MI.	Front Microbiol	10.3389/fmicb.2022.940865	2022
	Archaeal Hel308 suppresses recombination through a catalytic switch that controls DNA annealing.	Lever RJ, Simmons E, Gamble-Milner R, Buckley RJ, Harrison C, Parkes AJ, Mitchell L, Gausden JA, Skulj S, Bertosa B, Bolt EL, Allers T.	Nucleic Acids Res	10.1093/nar/gkad572	2023
	Bioengineering of air-filled protein nanoparticles by genetic and chemical functionalization.	Karan R, Renn D, Nozue S, Zhao L, Habuchi S, Allers T, Rueping M.	J Nanobiotechnology	10.1186/s12951-023-01866-7	2023
	Differences in homologous recombination and maintenance of heteropolyploidy between Haloferax volcanii and Haloferax mediterranei.	Dattani A, Sharon I, Shtifman-Segal E, Robinzon S, Gophna U, Allers T, Altman-Price N.	G3 (Bethesda)	10.1093/g3journal/jkac306	2023
	Ion-combination specific effects driving the enzymatic activity of halophilic alcohol dehydrogenase 2 from Haloferax volcanii in aqueous ionic liquid solvent mixtures.	Schindl A, Hagen ML, Cooley I, Jager CM, Warden AC, Zelzer M, Allers T, Croft AK.	RSC Sustain	10.1039/d3su00412k	2024
	Sec-Dependent Secretion of Subtilase SptE in Haloarchaea Facilitates Its Proper Folding and Heterocatalytic Processing by Halolysin SptA Extracellularly.	Mei S, Li M, Sun Y, Deng X, Chen N, Liu Y, Yin J, Luo H, Wu Y, He D, Gan F, Tang B, Tang XF.	Appl Environ Microbiol	10.1128/aem.00246-22	2022
	RNase W, a conserved ribonuclease family with a novel active site.	Vayssieres M, Juttner M, Haas K, Ancelin A, Marchfelder A, Leulliot N, Ferreira-Cerca S, Blaud M.	Nucleic Acids Res	10.1093/nar/gkae907	2024
	Histones and histone variant families in prokaryotes.	Schwab S, Hu Y, van Erp B, Cajili MKM, Hartmann MD, Hernandez Alvarez B, Alva V, Boyle AL, Dame RT.	Nat Commun	10.1038/s41467-024-52337-y	2024
	Quantitative Mass Spectrometry by SILAC in Haloferax volcanii.	Couto-Rodriguez RL, Gal D, McMillan LJ, Koh J, Chen S, Maupin-Furlow JA.	Methods Mol Biol	10.1007/978-1-0716-2445-6_16	2022
Metabolism	D-galactose catabolism in archaea: operation of the DeLey-Doudoroff pathway in Haloferax volcanii.	Tastensen JB, Johnsen U, Reinhardt A, Ortjohann M, Schonheit P.	FEMS Microbiol Lett	10.1093/femsle/fnaa029	2020
	SugarPy facilitates the universal, discovery-driven analysis of intact glycopeptides.	Schulze S, Oltmanns A, Fufezan C, Kragenbring J, Mormann M, Pohlschroder M, Hippler M.	Bioinformatics	10.1093/bioinformatics/btaa1042	2021
	Understanding the tolerance of halophilic archaea to stress landscapes.	Matarredona L, Zafrilla B, Camacho M, Bonete MJ, Esclapez J.	Environ Microbiol Rep	10.1111/1758-2229.70039	2024
	Archaeal type six secretion system mediates contact-dependent antagonism.	Zachs T, Malit JJL, Xu J, Schurch A, Sivabalasarma S, Nussbaum P, Albers SV, Pilhofer M.	Sci Adv	10.1126/sciadv.adp7088	2024
	Identification of structural and regulatory cell-shape determinants in Haloferax volcanii.	Schiller H, Hong Y, Kouassi J, Rados T, Kwak J, DiLucido A, Safer D, Marchfelder A, Pfeiffer F, Bisson A, Schulze S, Pohlschroder M.	Nat Commun	10.1038/s41467-024-45196-0	2024
	Bioactive molecules from haloarchaea: Scope and prospects for industrial and therapeutic applications.	Moopantakath J, Imchen M, Anju VT, Busi S, Dyavaiah M, Martinez-Espinosa RM, Kumavath R.	Front Microbiol	10.3389/fmicb.2023.1113540	2023
	Solution Structure and Dynamics of the Small Protein HVO_2922 from Haloferax volcanii.	Kubatova N, Jonker HRA, Saxena K, Richter C, Vogel V, Schreiber S, Marchfelder A, Schwalbe H.	Chembiochem	10.1002/cbic.201900085	2020
Metabolism	An Oscillating MinD Protein Determines the Cellular Positioning of the Motility Machinery in Archaea.	Nussbaum P, Ithurbide S, Walsh JC, Patro M, Delpech F, Rodriguez-Franco M, Curmi PMG, Duggin IG, Quax TEF, Albers SV.	Curr Biol	10.1016/j.cub.2020.09.073	2020
	Putative nucleotide-based second messengers in archaea.	van der Does C, Braun F, Ren H, Albers SV.	Microlife	10.1093/femsml/uqad027	2023
Metabolism	The Response of Haloferax volcanii to Salt and Temperature Stress: A Proteome Study by Label-Free Mass Spectrometry.	Jevtic Z, Stoll B, Pfeiffer F, Sharma K, Urlaub H, Marchfelder A, Lenz C.	Proteomics	10.1002/pmic.201800491	2019
	Bioinformatic and genetic characterization of three genes localized adjacent to the major replication origin of Haloferax volcanii.	Wolters M, Borst A, Pfeiffer F, Soppa J.	FEMS Microbiol Lett	10.1093/femsle/fnz238	2019
	Application of Archaea in Deubiquitinase-Like Enzyme Discovery and Activity Assay.	Hepowit NL, Maupin-Furlow JA.	Methods Mol Biol	10.1007/978-1-0716-2803-4_10	2023
Metabolism	In Vivo RNA Chemical Footprinting Analysis in Archaea.	Knuppel R, Fenk M, Juttner M, Ferreira-Cerca S.	Methods Mol Biol	10.1007/978-1-0716-0231-7_12	2020
	Halofilins as emerging bactofilin families of archaeal cell shape plasticity orchestrators.	Curtis Z, Escudeiro P, Mallon J, Leland O, Rados T, Dodge A, Andre K, Kwak J, Yun K, Isaac B, Martinez Pastor M, Schmid AK, Pohlschroder M, Alva V, Bisson A.	Proc Natl Acad Sci U S A	10.1073/pnas.2401583121	2024
Phenotype	Hypochlorite Stress Assay for Phenotypic Analysis of the Halophilic Archaeon Haloferax volcanii Using an Improved Incubation Method and Growth Monitoring.	Mondragon P, Hwang S, Schmid A, Maupin-Furlow JA.	Bio Protoc	10.21769/bioprotoc.4557	2022
Enzymology	Cloning, Expression, Characterization and Immobilization of a Recombinant Carboxylesterase from the Halophilic Archaeon, Halobacterium salinarum NCR-1.	Ortega-de la Rosa ND, Romero-Borbon E, Rodriguez JA, Camacho-Ruiz A, Cordova J.	Biomolecules	10.3390/biom14050534	2024
	Unidirectional gene pairs in archaea and bacteria require overlaps or very short intergenic distances for translational coupling via termination-reinitiation and often encode subunits of heteromeric complexes.	Huber M, Vogel N, Borst A, Pfeiffer F, Karamycheva S, Wolf YI, Koonin EV, Soppa J.	Front Microbiol	10.3389/fmicb.2023.1291523	2023
	Insights into the Lysine Acetylome of the Haloarchaeon Haloferax volcanii during Oxidative Stress by Quantitative SILAC-Based Proteomics.	Couto-Rodriguez RL, Koh J, Chen S, Maupin-Furlow JA.	Antioxidants (Basel)	10.3390/antiox12061203	2023
	Cas1 and Fen1 Display Equivalent Functions During Archaeal DNA Repair.	Wortz J, Smith V, Fallmann J, Konig S, Thuraisingam T, Walther P, Urlaub H, Stadler PF, Allers T, Hille F, Marchfelder A.	Front Microbiol	10.3389/fmicb.2022.822304	2022
Metabolism	Uptake of D-xylose and L-arabinose in Haloferax volcanii involves an ABC transporter of the CUT1 subfamily.	Johnsen U, Ortjohann M, Sutter JM, Geweke S, Schonheit P.	FEMS Microbiol Lett	10.1093/femsle/fnz089	2019
	ArcS from Thermococcus kodakarensis transfers L-lysine to preQ₀ nucleoside derivatives as minimum substrate RNAs.	Fujita S, Sugio Y, Kawamura T, Yamagami R, Oka N, Hirata A, Yokogawa T, Hori H.	J Biol Chem	10.1016/j.jbc.2024.107505	2024
	Expression and tandem affinity purification of 20S proteasomes and other multisubunit complexes in Haloferax volcanii.	Jia H, Couto-Rodriguez RL, Gal D, Mondragon P, Wassel PC, Yu D, Maupin-Furlow JA.	Methods Enzymol	10.1016/bs.mie.2021.08.002	2021
	Extracellular vesicle formation in Euryarchaeota is driven by a small GTPase.	Mills J, Gebhard LJ, Schubotz F, Shevchenko A, Speth DR, Liao Y, Duggin IG, Marchfelder A, Erdmann S.	Proc Natl Acad Sci U S A	10.1073/pnas.2311321121	2024
	Haloferax volcanii.	Pohlschroder M, Schulze S.	Trends Microbiol	10.1016/j.tim.2018.10.004	2019
	TroR is the primary regulator of the iron homeostasis transcription network in the halophilic archaeon Haloferax volcanii.	Martinez Pastor M, Sakrikar S, Hwang S, Hackley RK, Soborowski AL, Maupin-Furlow JA, Schmid AK.	Nucleic Acids Res	10.1093/nar/gkad997	2024
Genetics	Cooperation between two modes for DNA replication initiation in the archaeon Thermococcus barophilus.	Mc Teer L, Moalic Y, Cueff-Gauchard V, Catchpole R, Hogrel G, Lu Y, Laurent S, Hemon M, Aube J, Leroy E, Roussel E, Oberto J, Flament D, Dulermo R.	mBio	10.1128/mbio.03200-23	2024
Enzymology	Homologs of aquifex aeolicus protein-only RNase P are not the major RNase P activities in the archaea haloferax volcanii and methanosarcina mazei.	Schwarz TS, Waber NB, Feyh R, Weidenbach K, Schmitz RA, Marchfelder A, Hartmann RK.	IUBMB Life	10.1002/iub.2122	2019
	Chromatin and gene regulation in archaea.	Blombach F, Werner F.	Mol Microbiol	10.1111/mmi.15302	2025
	Development of a genetic system for Haloferax gibbonsii LR2-5, model host for haloarchaeal viruses.	Tittes C, Nijland J, Schoentag AMC, Hackl T, Di Cianni N, Marchfelder A, Quax TEF.	Appl Environ Microbiol	10.1128/aem.00129-24	2024
	CRISPRi as an efficient tool for gene repression in archaea.	Stachler AE, Schwarz TS, Schreiber S, Marchfelder A.	Methods	10.1016/j.ymeth.2019.05.023	2020
Enzymology	Structural and Kinetic Insights Into the Molecular Basis of Salt Tolerance of the Short-Chain Glucose-6-Phosphate Dehydrogenase From Haloferax volcanii.	Fuentes-Ugarte N, Herrera SM, Maturana P, Castro-Fernandez V, Guixe V.	Front Microbiol	10.3389/fmicb.2021.730429	2021
	Variation of tRNA modifications with and without intron dependency.	Hayashi S.	Front Genet	10.3389/fgene.2024.1460902	2024
Enzymology	Thermostable Enzyme Variants in the Lower Mevalonate Pathway Improve Isoprenoid Production by Cell-Free Biocatalysis.	Sarnik SA, Martinsen MR, Korman TP, Schwartz DK, Kaar JL, Bomble YJ.	ACS Sustain Chem Eng	10.1021/acssuschemeng.5c03763	2025
	Thermal-bias PCR: generation of amplicon libraries without degenerate primer interference.	Moore SD.	PeerJ	10.7717/peerj.20241	2025
Metabolism	Denovo designing: a novel signal peptide for tat translocation pathway to transport activin A to the periplasmic space of E. coli.	Zandsalimi F, Hajihassan Z, Hamidi R.	Biotechnol Lett	10.1007/s10529-019-02752-9	2020
	Polyploidy in halophilic archaea: regulation, evolutionary advantages, and gene conversion.	Ludt K, Soppa J.	Biochem Soc Trans	10.1042/bst20190256	2019
Biotechnology	Bacterioruberin extracts from a genetically modified hyperpigmented Haloferax volcanii strain: antioxidant activity and bioactive properties on sperm cells.	Zalazar L, Pagola P, Miro MV, Churio MS, Cerletti M, Martinez C, Iniesta-Cuerda M, Soler AJ, Cesari A, De Castro R.	J Appl Microbiol	10.1111/jam.14160	2019
	Functional redundancy of ubiquitin-like sulfur-carrier proteins facilitates flexible, efficient sulfur utilization in the primordial archaeon Thermococcus kodakarensis.	Hidese R, Ohira T, Sakakibara S, Suzuki T, Shigi N, Fujiwara S.	mBio	10.1128/mbio.00534-24	2024
Pathogenicity	Isolation of a virus causing a chronic infection in the archaeal model organism Haloferax volcanii reveals antiviral activities of a provirus.	Alarcon-Schumacher T, Naor A, Gophna U, Erdmann S.	Proc Natl Acad Sci U S A	10.1073/pnas.2205037119	2022
Enzymology	l-Rhamnose catabolism in archaea.	Reinhardt A, Johnsen U, Schonheit P.	Mol Microbiol	10.1111/mmi.14213	2019
	A narrow range of transcript-error rates across the Tree of Life.	Li W, Baehr S, Marasco M, Reyes L, Brister D, Pikaard CS, Gout JF, Vermulst M, Lynch M.	Sci Adv	10.1126/sciadv.adv9898	2025
	Tat-fimbriae ("tafi"): An unusual type of haloarchaeal surface structure depending on the twin-arginine translocation pathway.	Galeva AV, Zhao D, Syutkin AS, Topilina MY, Shchyogolev SY, Pavlova EY, Selivanova OM, Kireev II, Surin AK, Burygin GL, Liu J, Xiang H, Pyatibratov MG.	iScience	10.1016/j.isci.2025.111793	2025
	High-level synthesis and secretion of laccase, a metalloenzyme biocatalyst, by the halophilic archaeon Haloferax volcanii.	Kasirajan L, Adams Z, Couto-Rodriguez RL, Gal D, Jia H, Mondragon P, Wassel PC, Yu D, Uthandi S, Maupin-Furlow JA.	Methods Enzymol	10.1016/bs.mie.2021.05.012	2021
	The Best of Both Worlds: Discovery-Driven Learning through a Lab-Seminar Approach.	Egan MS, Hogan K, Maupin-Furlow J, Pohlschroder M.	J Microbiol Biol Educ	10.1128/jmbe.00031-22	2022
Metabolism	Proteomic Study of the Exponential-Stationary Growth Phase Transition in the Haloarchaea Natrialba magadii and Haloferax volcanii.	Cerletti M, Gimenez MI, Troetschel C, D' Alessandro C, Poetsch A, De Castro RE, Paggi RA, Paggi RA.	Proteomics	10.1002/pmic.201800116	2018
	The Hypersaline Archaeal Histones HpyA and HstA Are DNA Binding Proteins That Defy Categorization According to Commonly Used Functional Criteria.	Sakrikar S, Hackley RK, Martinez-Pastor M, Darnell CL, Vreugdenhil A, Schmid AK.	mBio	10.1128/mbio.03449-22	2023
Metabolism	Distinct Regions of the Haloferax volcanii Dolichol Phosphate-Mannose Synthase AglD Mediate the Assembly and Subsequent Processing of the Lipid-Linked Mannose.	Zaretsky M, Guan Z, Zarivach R, Eichler J.	J Bacteriol	10.1128/jb.00447-21	2022
	tDR-quant: a reliable electroporation-based approach for quantifying tRNA-derived fragments binding to ribosomes.	Bakowska-Zywicka K, Tyczewska A.	FEMS Yeast Res	10.1093/femsyr/foaf051	2025
	Acetate Metabolism in Archaea: Characterization of an Acetate Transporter and of Enzymes Involved in Acetate Activation and Gluconeogenesis in Haloferax volcanii.	Kuprat T, Johnsen U, Ortjohann M, Schonheit P.	Front Microbiol	10.3389/fmicb.2020.604926	2020
	Neighboring inteins interfere with one another's homing capacity.	Turgeman-Grott I, Arsenault D, Yahav D, Feng Y, Miezner G, Naki D, Peri O, Papke RT, Gogarten JP, Gophna U.	PNAS Nexus	10.1093/pnasnexus/pgad354	2023
Enzymology	Catalytic linkage between caspase activity and proteostasis in Archaea.	Seth-Pasricha M, Senn S, Sanman LE, Bogyo M, Nanda V, Bidle KA, Bidle KD.	Environ Microbiol	10.1111/1462-2920.14456	2019
	Denovo designing: a novel signal peptide for tat translocation pathway to transport activin A to the periplasmic space of E. coli	Zandsalimi F, Hajihassan Z, Hamidi R.	Biotechnol Lett		2020
	Structural basis of translation inhibition by a valine tRNA-derived fragment.	Wu Y, Ni MT, Wang YH, Wang C, Hou H, Zhang X, Zhou J.	Life Sci Alliance	10.26508/lsa.202302488	2024
	Toxicity Assessment and Bioremediation of Deep Eutectic Solvents by Haloferax mediterranei: A Step toward Sustainable Circular Chemistry.	Martinez G, Guillena G, Martinez-Espinosa RM.	ChemSusChem	10.1002/cssc.202500825	2025
	Significant Enhancement of Structural Stability of the Hyperhalophilic ADH from Haloferax volcanii via Entrapment on Metal Organic Framework Support.	Carucci C, Bruen L, Gascon V, Paradisi F, Magner E.	Langmuir	10.1021/acs.langmuir.8b01037	2018
Metabolism	Conserved residues are critical for Haloferax volcanii archaeosortase catalytic activity: Implications for convergent evolution of the catalytic mechanisms of non-homologous sortases from archaea and bacteria.	Abdul Halim MF, Rodriguez R, Stoltzfus JD, Duggin IG, Pohlschroder M.	Mol Microbiol	10.1111/mmi.13935	2018
Metabolism	Denitrifying haloarchaea within the genus Haloferax display divergent respiratory phenotypes, with implications for their release of nitrogenous gases.	Torregrosa-Crespo J, Pire C, Martinez-Espinosa RM, Bergaust L.	Environ Microbiol	10.1111/1462-2920.14474	2019
	Haloferax volcanii Proteome Response to Deletion of a Rhomboid Protease Gene.	Costa MI, Cerletti M, Paggi RA, Trotschel C, De Castro RE, Poetsch A, Gimenez MI.	J Proteome Res	10.1021/acs.jproteome.7b00530	2018
Metabolism	LonB Protease Is a Novel Regulator of Carotenogenesis Controlling Degradation of Phytoene Synthase in Haloferax volcanii.	Cerletti M, Paggi R, Troetschel C, Ferrari MC, Guevara CR, Albaum S, Poetsch A, De Castro R.	J Proteome Res	10.1021/acs.jproteome.7b00809	2018
	RecJ3/4-aRNase J form a Ubl-associated nuclease complex functioning in survival against DNA damage in Haloferax volcanii.	Jia H, Dantuluri S, Margulies S, Smith V, Lever R, Allers T, Koh J, Chen S, Maupin-Furlow JA.	mBio	10.1128/mbio.00852-23	2023
Genetics	Mutations Affecting HVO_1357 or HVO_2248 Cause Hypermotility in Haloferax volcanii, Suggesting Roles in Motility Regulation.	Collins M, Afolayan S, Igiraneza AB, Schiller H, Krespan E, Beiting DP, Dyall-Smith M, Pfeiffer F, Pohlschroder M.	Genes (Basel)	10.3390/genes12010058	2020
Metabolism	Co-expression and purification of the RadA recombinase with the RadB paralog from Haloferax volcanii yields heteromeric ring-like structures.	Patoli BB, Winter JA, Patoli AA, Delahay RM, Bunting KA.	Microbiology (Reading)	10.1099/mic.0.000562	2017
Metabolism	Glucose Metabolism and Acetate Switch in Archaea: the Enzymes in Haloferax volcanii.	Kuprat T, Ortjohann M, Johnsen U, Schonheit P.	J Bacteriol	10.1128/jb.00690-20	2021
Metabolism	Mutations in the major gas vesicle protein GvpA and impacts on gas vesicle formation in Haloferax volcanii.	Knitsch R, Schneefeld M, Weitzel K, Pfeifer F, Pfeifer F.	Mol Microbiol	10.1111/mmi.13833	2017
	Advanced Understanding of Prokaryotic Biofilm Formation through Use of a Cost-Effective and Versatile Multipanel Adhesion (mPAD) Mount.	Schulze S, Schiller H, Solomonic J, Telhan O, Costa K, Pohlschroder M.	Appl Environ Microbiol	10.1128/aem.02283-21	2022
Metabolism	Characterization of a pentonolactonase involved in D-xylose and L-arabinose catabolism in the haloarchaeon Haloferax volcanii.	Sutter JM, Johnsen U, Schonheit P.	FEMS Microbiol Lett	10.1093/femsle/fnx140	2017
	Regulation of DNA Topology in Archaea: State of the Art and Perspectives.	Villain P, Basta T.	Mol Microbiol	10.1111/mmi.15328	2025
Proteome	Revealing the small proteome of Haloferax volcanii by combining ribosome profiling and small-protein optimized mass spectrometry.	Hadjeras L, Bartel J, Maier LK, Maass S, Vogel V, Svensson SL, Eggenhofer F, Gelhausen R, Muller T, Alkhnbashi OS, Backofen R, Becher D, Sharma CM, Marchfelder A.	Microlife	10.1093/femsml/uqad001	2023
Transcriptome	Halobacterium salinarum and Haloferax volcanii Comparative Transcriptomics Reveals Conserved Transcriptional Processing Sites.	Ibrahim AGAE, Vencio RZN, Lorenzetti APR, Koide T.	Genes (Basel)	10.3390/genes12071018	2021
Pathogenicity	Nitrate-Responsive Suppression of Dimethyl Sulfoxide Respiration in a Facultative Anaerobic Haloarchaeon, Haloferax volcanii.	Koyanagi I, Dohra H, Fujiwara T.	J Bacteriol	10.1128/jb.00655-20	2021
Metabolism	Haloquadratum walsbyi Yields a Versatile, NAD⁺/NADP⁺ Dual Affinity, Thermostable, Alcohol Dehydrogenase (HwADH).	Cassidy J, Paradisi F.	Mol Biotechnol	10.1007/s12033-018-0083-6	2018
	Sulfated lactosyl archaeol (SLA) archaeosomes as a vaccine adjuvant.	Akache B, McCluskie MJ.	Hum Vaccin Immunother	10.1080/21645515.2024.2395081	2024
	Putative Nucleotide-Based Second Messengers in the Archaeal Model Organisms Haloferax volcanii and Sulfolobus acidocaldarius.	Braun F, Recalde A, Bahre H, Seifert R, Albers SV.	Front Microbiol	10.3389/fmicb.2021.779012	2021
	Identification of the D-glucuronyl C5-epimerase that introduces iduronic acid into N-linked glycans decorating archaeal glycoproteins.	Vershinin Z, Zaretsky M, Notaro A, Yu D, Molinaro A, Sofer S, Grossman-Haham I, De Castro C, Eichler J.	Commun Biol	10.1038/s42003-025-08987-9	2025
	Structure of a functional archaellum in Bacteria of the Chloroflexota phylum.	Sivabalasarma S, Taib N, Mollat CL, Joest M, Steimle S, Gribaldo S, Albers SV.	Nat Microbiol	10.1038/s41564-025-02110-8	2025
	Life in the brine of Lunenburg, Germany: unveiling microorganisms associated with Zechstein salt deposits.	Runzheimer K, Schwab L, Engel D, Schaudinn C, Laue M, Rebrosova K, Beblo-Vranesevic K, Azizah M, Leuko S.	Front Microbiol	10.3389/fmicb.2025.1625916	2025
Metabolism	Assembling Glycan-Charged Dolichol Phosphates: Chemoenzymatic Synthesis of a Haloferax volcanii N-Glycosylation Pathway Intermediate.	Elharar Y, Podilapu AR, Guan Z, Kulkarni SS, Eichler J.	Bioconjug Chem	10.1021/acs.bioconjchem.7b00436	2017
Enzymology	Extreme halophilic alcohol dehydrogenase mediated highly efficient syntheses of enantiopure aromatic alcohols.	Alsafadi D, Alsalman S, Paradisi F.	Org Biomol Chem	10.1039/c7ob02299a	2017
	Analysis of Cell-Cell Bridges in Haloferax volcanii Using Electron Cryo-Tomography Reveal a Continuous Cytoplasm and S-Layer.	Sivabalasarma S, Wetzel H, Nussbaum P, van der Does C, Beeby M, Albers SV.	Front Microbiol	10.3389/fmicb.2020.612239	2020
	An archaeal Cas3 protein facilitates rapid recovery from DNA damage.	Miezner G, Turgeman-Grott I, Zatopek KM, Gardner AF, Reshef L, Choudhary DK, Alstetter M, Allers T, Marchfelder A, Gophna U.	Microlife	10.1093/femsml/uqad007	2023
	A Haloarchaeal Transcriptional Regulator That Represses the Expression of CRISPR-Associated Genes.	Turgeman-Grott I, Shalev Y, Shemesh N, Levy R, Eini I, Pasmanik-Chor M, Gophna U.	Microorganisms	10.3390/microorganisms12091772	2024
Genetics	Unexplored diversity and potential functions of extra-chromosomal elements.	Liu H, Sun J, Si J, Liao Y, Bai J, Li X, Wang L, Cai K, Ni W, Zhou P, Hu S.	mSystems	10.1128/msystems.00175-25	2025
Enzymology	Haloferax volcanii UbaA, catalytic engine for sampylation and sulfur transfer.	Bochtler M, Piasecka A.	FEBS J	10.1111/febs.13826	2016
	Transposon Insertion Mutagenesis for Archaeal Gene Discovery.	Kiljunen S, Pajunen MI, Savilahti H.	Methods Mol Biol	10.1007/978-1-4939-6472-7_20	2017
	Archaeal cell biology: diverse functions of tubulin-like cytoskeletal proteins at the cell envelope.	Liao Y, Ithurbide S, de Silva RT, Erdmann S, Duggin IG.	Emerg Top Life Sci	10.1042/etls20180026	2018
Metabolism	The stress of carrying CRISPR-Cas.	Haider D, Bauer R, Grempels A, Roscher R, Aslan CC, Mauerer S, Spellerberg B.	Virulence	10.1080/21505594.2025.2541701	2025
	Characterization of Non-selected Intermolecular Gene Conversion in the Polyploid Haloarchaeon Haloferax volcanii.	Wasser D, Borst A, Hammelmann M, Ludt K, Soppa J.	Front Microbiol	10.3389/fmicb.2021.680854	2021
Genetics	Using the pan-genomic framework for the discovery of genomic islands in the haloarchaeon Halorubrum ezzemoulense.	Feng Y, Arsenault D, Louyakis AS, Altman-Price N, Gophna U, Papke RT, Gogarten JP.	mBio	10.1128/mbio.00408-24	2024
	The role of tRNA identity elements in aminoacyl-tRNA editing.	Cruz E, Vargas-Rodriguez O.	Front Microbiol	10.3389/fmicb.2024.1437528	2024
Pathogenicity	The infection cycle of the haloarchaeal virus HFTV1 is tightly regulated and strongly inhibits motility of its host.	Schwarzer S, Backer LE, Nijland JG, Hayani Aji I, de Jong A, Moraru C, Steglich C, Quax TEF.	mSystems	10.1128/msystems.00704-25	2025
	Improving the genetic system for Halorubrum lacusprofundi to allow in-frame deletions.	Gebhard LJ, Duggin IG, Erdmann S.	Front Microbiol	10.3389/fmicb.2023.1095621	2023
	AepG is a glucuronosyltransferase involved in acidic exopolysaccharide synthesis and contributes to environmental adaptation of Haloarcula hispanica.	Pei C, Lu H, Ma J, Eichler J, Guan Z, Gao L, Liu L, Zhou H, Yang J, Jin C.	J Biol Chem	10.1016/j.jbc.2023.102911	2023
	One Advantage of Being Polyploid: Prokaryotes of Various Phylogenetic Groups Can Grow in the Absence of an Environmental Phosphate Source at the Expense of Their High Genome Copy Numbers.	Bruck P, Wasser D, Soppa J.	Microorganisms	10.3390/microorganisms11092267	2023
	Rft1 catalyzes lipid-linked oligosaccharide translocation across the ER membrane.	Chen S, Pei CX, Xu S, Li H, Liu YS, Wang Y, Jin C, Dean N, Gao XD.	Nat Commun	10.1038/s41467-024-48999-3	2024
	Functional diversity and molecular interactions of small membrane proteins in bacteria.	Yuan J, Koch HG, Berghoff BA.	Microlife	10.1093/femsml/uqaf035	2025
	The Human Archaeome: Commensals, Opportunists, or Emerging Pathogens?	Ruden DM.	Pathogens	10.3390/pathogens14111111	2025
	SANS reveals lipid-dependent oligomerization of an intramembrane aspartyl protease from H. volcanii.	Thomas GM, Wu Y, Leite W, Pingali SV, Weiss KL, Grant AJ, Diggs MW, Schmidt-Krey I, Gutishvili G, Gumbart JC, Urban VS, Lieberman RL.	Biophys J	10.1016/j.bpj.2024.05.029	2024
	Establishing Live-Cell Single-Molecule Localization Microscopy Imaging and Single-Particle Tracking in the Archaeon Haloferax volcanii.	Turkowyd B, Schreiber S, Wortz J, Segal ES, Mevarech M, Duggin IG, Marchfelder A, Endesfelder U.	Front Microbiol	10.3389/fmicb.2020.583010	2020
Biotechnology	How Small Proteins Adjust the Metabolism of Cyanobacteria Under Stress: The Role of Small Proteins in Cyanobacterial Stress Responses.	Kraus A, Hess WR.	Bioessays	10.1002/bies.202400245	2025
	Identification of NAD-RNA species and ADPR-RNA decapping in Archaea.	Gomes-Filho JV, Breuer R, Morales-Filloy HG, Pozhydaieva N, Borst A, Paczia N, Soppa J, Hofer K, Jaschke A, Randau L.	Nat Commun	10.1038/s41467-023-43377-x	2023
	Insights into gene expression changes under conditions that facilitate horizontal gene transfer (mating) of a model archaeon.	Makkay AM, Louyakis AS, Ram-Mohan N, Gophna U, Gogarten JP, Papke RT.	Sci Rep	10.1038/s41598-020-79296-w	2020
Stress	Environmental factors influence the Haloferax volcanii S-layer protein structure.	Rodrigues-Oliveira T, Souza AA, Kruger R, Schuster B, Maria de Freitas S, Kyaw CM.	PLoS One	10.1371/journal.pone.0216863	2019
Genetics	The Archaeal Cell Cycle.	Cezanne A, Foo S, Kuo YW, Baum B.	Annu Rev Cell Dev Biol	10.1146/annurev-cellbio-111822-120242	2024
	Agl28 and Agl29 are key components of a Halobacterium salinarum N-glycosylation pathway.	Vershinin Z, Zaretsky M, Guan Z, Eichler J.	FEMS Microbiol Lett	10.1093/femsle/fnad017	2023
	Transcriptome profiling of Nudix hydrolase gene deletions in the thermoacidophilic archaeon Sulfolobus acidocaldarius.	Breuer R, Gomes-Filho JV, Yuan J, Randau L.	Front Microbiol	10.3389/fmicb.2023.1197877	2023
Pathogenicity	CRISPR-based genetic tools for the study of host-microbe interactions.	Echavarria Galindo M, Lai Y.	Infect Immun	10.1128/iai.00510-24	2025
Genetics	Inhibiting NAD+-dependent DNA ligase activity with 2-(cyclopentyloxy)-5'-deoxyadenosine (CPOdA) offers a new tool for DNA replication and repair studies in the model archaeon Haloferax volcanii.	Giroux X, MacNeill SA.	FEMS Microbiol Lett	10.1093/femsle/fnv181	2015
	Elucidation of the Translation Initiation Factor Interaction Network of Haloferax volcanii Reveals Coupling of Transcription and Translation in Haloarchaea.	Schramm F, Borst A, Linne U, Soppa J.	Front Microbiol	10.3389/fmicb.2021.742806	2021
Enzymology	Transcriptional regulation of dimethyl sulfoxide respiration in a haloarchaeon, Haloferax volcanii.	Qi Q, Ito Y, Yoshimatsu K, Fujiwara T.	Extremophiles	10.1007/s00792-015-0794-6	2016
	The use of thermostable fluorescent proteins for live imaging in Sulfolobus acidocaldarius.	Recalde A, Abdul-Nabi J, Junker P, van der Does C, Elsasser J, van Wolferen M, Albers SV.	Front Microbiol	10.3389/fmicb.2024.1445186	2024
	A bioluminescent reporter for the halophilic archaeon Haloferax volcanii.	Davis CR, Johnson CH, Robertson JB.	Extremophiles	10.1007/s00792-020-01193-x	2020
Metabolism	Regulated Iron Siderophore Production of the Halophilic Archaeon Haloferax volcanii.	Niessen N, Soppa J.	Biomolecules	10.3390/biom10071072	2020
	Improved growth and morphological plasticity of Haloferax volcanii.	de Silva RT, Abdul-Halim MF, Pittrich DA, Brown HJ, Pohlschroder M, Duggin IG.	Microbiology (Reading)	10.1099/mic.0.001012	2021
	Functional Insights of Salinity Stress-Related Pathways in Metagenome-Resolved Methanothrix Genomes.	Gagliano MC, Sampara P, Plugge CM, Temmink H, Sudmalis D, Ziels RM.	Appl Environ Microbiol	10.1128/aem.02449-21	2022
Metabolism	d-Ribose Catabolism in Archaea: Discovery of a Novel Oxidative Pathway in Haloarcula Species.	Johnsen U, Sutter JM, Reinhardt A, Pickl A, Wang R, Xiang H, Schonheit P.	J Bacteriol	10.1128/jb.00608-19	2020
Phylogeny	Unravelling Prokaryotic Codon Usage: Insights from Phylogeny, Influencing Factors and Pathogenicity.	Dahal U, Bansal A.	Curr Genomics	10.2174/0113892029325491240919151045	2025
	Structural characterization of the N-linked pentasaccharide decorating glycoproteins of the halophilic archaeon Haloferax volcanii.	Kandiba L, Lin CW, Aebi M, Eichler J, Guerardel Y.	Glycobiology	10.1093/glycob/cww014	2016
	In Vitro Antioxidant, Antihemolytic, and Anticancer Activity of the Carotenoids from Halophilic Archaea.	Hou J, Cui HL.	Curr Microbiol	10.1007/s00284-017-1374-z	2018
	Engineering Saccharomyces cerevisiae for growth on xylose using an oxidative pathway.	Tanaka K, Yukawa T, Bamba T, Wakiya M, Kumokita R, Jin YS, Kondo A, Hasunuma T.	Appl Microbiol Biotechnol	10.1007/s00253-025-13417-1	2025
Metabolism	DNA replication restart and cellular dynamics of Hef helicase/nuclease protein in Haloferax volcanii.	Lestini R, Delpech F, Myllykallio H.	Biochimie	10.1016/j.biochi.2015.07.022	2015
	Transcriptomic evidence for an energetically advantageous relationship between Syntrophomonas wolfei and Methanothrix soehngenii.	Besteman MS, Doloman A, Sousa DZ.	Environ Microbiol Rep	10.1111/1758-2229.13276	2024
	Air-loaded Gas Vesicle Nanoparticles Promote Cell Growth in Three-dimensional Bioprinted Tissue Constructs.	Alshehri S, Karan R, Ghalayini S, Kahin K, Khan Z, Renn D, Mathew S, Rueping M, Hauser CAE.	Int J Bioprint	10.18063/ijb.v8i3.489	2022
Biotechnology	Production of halophilic proteins using Haloferax volcanii H1895 in a stirred-tank bioreactor.	Strillinger E, Grotzinger SW, Allers T, Eppinger J, Weuster-Botz D.	Appl Microbiol Biotechnol	10.1007/s00253-015-7007-1	2016
	Identification and characterisation of two functional antibiotic MATE efflux pumps in the archaeon Halorubrum amylolyticum.	Fakhoury AA, Thompson TP, Rahman KM, Megaw J, McAteer MI, Skvortsov T, Kelly SA, Gilmore BF.	NPJ Antimicrob Resist	10.1038/s44259-024-00036-5	2024
Enzymology	The oxidative pentose phosphate pathway in the haloarchaeon Haloferax volcanii involves a novel type of glucose-6-phosphate dehydrogenase--The archaeal Zwischenferment.	Pickl A, Schonheit P.	FEBS Lett	10.1016/j.febslet.2015.03.026	2015
	Machine learning and statistics shape a novel path in archaeal promoter annotation.	Martinez GS, Perez-Rueda E, Sarkar S, Kumar A, de Avila E Silva S.	BMC Bioinformatics	10.1186/s12859-022-04714-x	2022
	Probing archaeal cell biology: exploring the use of dyes in the imaging of Sulfolobus cells.	Cezanne A, Hoogenberg B, Baum B.	Front Microbiol	10.3389/fmicb.2023.1233032	2023
Genetics	Remote Homology Detection Identifies a Eukaryotic RPA DBD-C-like DNA Binding Domain as a Conserved Feature of Archaeal Rpa1-Like Proteins.	MacNeill SA.	Front Mol Biosci	10.3389/fmolb.2021.675229	2021
	Understanding High-Salt and Cold Adaptation of a Polyextremophilic Enzyme.	Karan R, Mathew S, Muhammad R, Bautista DB, Vogler M, Eppinger J, Oliva R, Cavallo L, Arold ST, Rueping M.	Microorganisms	10.3390/microorganisms8101594	2020
	Advanced Strategies for Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) Production: PHA Synthase Homologous Overexpression in the Extremophile Haloferax mediterranei.	Simica A, Segovia Y, Navarro-Sempere A, Martinez-Espinosa RM, Pire C.	Mar Drugs	10.3390/md23040166	2025
	Adaptation reduces competitive dominance and alters community assembly.	Nadeau CP, Farkas TE, Makkay AM, Papke RT, Urban MC.	Proc Biol Sci	10.1098/rspb.2020.3133	2021
Metabolism	Everyone loves an underdog: metabolic engineering of the xylose oxidative pathway in recombinant microorganisms.	Valdehuesa KNG, Ramos KRM, Nisola GM, Banares AB, Cabulong RB, Lee WK, Liu H, Chung WJ.	Appl Microbiol Biotechnol	10.1007/s00253-018-9186-z	2018
	Microbial hauberks: composition and function of surface layer proteins in gammaproteobacterial methanotrophs.	Hamilton R, Gebbie W, Bowman C, Mantanona A, Kalyuzhnaya MG.	Appl Environ Microbiol	10.1128/aem.01364-24	2025
	A conserved transcription factor controls gluconeogenesis via distinct targets in hypersaline-adapted archaea with diverse metabolic capabilities.	Hackley RK, Vreugdenhil-Hayslette A, Darnell CL, Schmid AK.	PLoS Genet	10.1371/journal.pgen.1011115	2024
	Protein modification by a eukaryotic-like ubiquitin-related modifier in the hyperthermophilic archaeon Saccharolobus islandicus.	Cao J, Xiong D, Zheng X, Yuan W, Huang L.	mSystems	10.1128/msystems.00580-25	2025
	In vitro evaluation of archaeosome vehicles for transdermal vaccine delivery.	Jia Y, McCluskie MJ, Zhang D, Monette R, Iqbal U, Moreno M, Sauvageau J, Williams D, Deschatelets L, Jakubek ZJ, Krishnan L.	J Liposome Res	10.1080/08982104.2017.1376683	2018
Metabolism	Effects of ionic strength on the folding and stability of SAMP1, a ubiquitin-like halophilic protein.	Mizukami T, Bedford JT, Liao S, Greene LH, Roder H.	Biophys J	10.1016/j.bpj.2022.01.010	2022
Metabolism	Important roles for membrane lipids in haloarchaeal bioenergetics.	Kellermann MY, Yoshinaga MY, Valentine RC, Wormer L, Valentine DL.	Biochim Biophys Acta	10.1016/j.bbamem.2016.08.010	2016
	Insights into the Distribution and Functional Properties of l-Asparaginase in the Archaeal Domain and Characterization of Picrophilus torridus Asparaginase Belonging to the Novel Family Asp2like1.	Sharma A, Kaushik V, Goel M.	ACS Omega	10.1021/acsomega.2c01127	2022
	Nature should be the model for microbial sciences.	Baker BJ, Hyde E, Leao P.	J Bacteriol	10.1128/jb.00228-24	2024
	Characterization and mechanism investigation of salt-activated methionine sulfoxide reductase A from halophiles.	Zhou S, Pan B, Kuang X, Chen S, Liu L, Song Y, Zhao Y, Xu X, Cheng X, Yang J.	iScience	10.1016/j.isci.2024.110806	2024
	Cellular and Genomic Properties of Haloferax gibbonsii LR2-5, the Host of Euryarchaeal Virus HFTV1.	Tittes C, Schwarzer S, Pfeiffer F, Dyall-Smith M, Rodriguez-Franco M, Oksanen HM, Quax TEF.	Front Microbiol	10.3389/fmicb.2021.625599	2021
Enzymology	Motile ghosts of the halophilic archaeon, Haloferax volcanii.	Kinosita Y, Mikami N, Li Z, Braun F, Quax TEF, van der Does C, Ishmukhametov R, Albers SV, Berry RM.	Proc Natl Acad Sci U S A	10.1073/pnas.2009814117	2020
Metabolism	Molecular Genetic Methods to Study DNA Replication Protein Function in Haloferax volcanii, A Model Archaeal Organism.	Giroux X, MacNeill SA.	Methods Mol Biol	10.1007/978-1-4939-2596-4_13	2015
Enzymology	Identification and characterization of 2-keto-3-deoxygluconate kinase and 2-keto-3-deoxygalactonate kinase in the haloarchaeon Haloferax volcanii.	Pickl A, Johnsen U, Archer RM, Schonheit P.	FEMS Microbiol Lett	10.1111/1574-6968.12617	2014
	Carotenoids from Halophilic Archaea: A Novel Approach to Improve Egg Quality and Cecal Microbiota in Laying Hens.	Dou X, Zhang G, Tang H, Chen X, Chen B, Mei Y, Jiao H, Ren M.	Animals (Basel)	10.3390/ani14233470	2024
Metabolism	A novel archaeal DNA repair factor that acts with the UvrABC system to repair mitomycin C-induced DNA damage in a PCNA-dependent manner.	Giroux X, MacNeill SA.	Mol Microbiol	10.1111/mmi.13210	2016
	Circular RNA: A promising new star of vaccine.	Xie J, Ye F, Deng X, Tang Y, Liang JY, Huang X, Sun Y, Tang H, Lei J, Zheng S, Zou Y.	J Transl Int Med	10.2478/jtim-2023-0122	2023
Metabolism	Global role of the membrane protease LonB in Archaea: Potential protease targets revealed by quantitative proteome analysis of a lonB mutant in Haloferax volcanii.	Cerletti M, Paggi RA, Guevara CR, Poetsch A, De Castro RE.	J Proteomics	10.1016/j.jprot.2015.03.016	2015
Genetics	Why Is the UAG (Amber) Stop Codon Almost Absent in Highly Expressed Bacterial Genes?	Belin D, Puigbo P.	Life (Basel)	10.3390/life12030431	2022
	Chase Assay of Protein Stability in Haloferax volcanii.	Fu X, Maupin-Furlow JA.	Bio Protoc	10.21769/bioprotoc.2186	2017
Enzymology	A simple technique to improve the resolution of membrane acidic proteins of the haloarchaeon Haloferax volcanii by 2D electrophoresis.	Paggi RA, Gimenez MI, De Castro RE, Cesari A.	Electrophoresis	10.1002/elps.201400407	2014
	Analysis of the Brucella suis Twin Arginine Translocation System and Its Substrates Shows That It Is Essential for Viability.	Riquelme E, Omarova S, Ize B, O'Callaghan D.	Infect Immun	10.1128/iai.00459-22	2023
Metabolism	Identifying Small Open Reading Frames in Prokaryotes with Ribosome Profiling.	Vazquez-Laslop N, Sharma CM, Mankin A, Buskirk AR.	J Bacteriol	10.1128/jb.00294-21	2022
	Cell division protein CdpA organises and anchors the midcell ring in haloarchaea	Liao Y, Shinde V, Hu D, Xu Z, Soderstrom B, Michie K, Duggin I.	Nat Commun		2025
Metabolism	XacR - a novel transcriptional regulator of D-xylose and L-arabinose catabolism in the haloarchaeon Haloferax volcanii.	Johnsen U, Sutter JM, Schulz AC, Tastensen JB, Schonheit P.	Environ Microbiol	10.1111/1462-2920.12603	2015
Metabolism	Cyclic nucleotides in archaea: Cyclic di-AMP in the archaeon Haloferax volcanii and its putative role.	Braun F, Thomalla L, van der Does C, Quax TEF, Allers T, Kaever V, Albers SV.	Microbiologyopen	10.1002/mbo3.829	2019
	The Role of the Universally Conserved ATPase YchF/Ola1 in Translation Regulation during Cellular Stress.	Landwehr V, Milanov M, Hong J, Koch HG.	Microorganisms	10.3390/microorganisms10010014	2021
Genetics	Open Issues for Protein Function Assignment in Haloferax volcanii and Other Halophilic Archaea.	Pfeiffer F, Dyall-Smith M.	Genes (Basel)	10.3390/genes12070963	2021
	Comparative Analysis of rRNA Removal Methods for RNA-Seq Differential Expression in Halophilic Archaea.	Pastor MM, Sakrikar S, Rodriguez DN, Schmid AK.	Biomolecules	10.3390/biom12050682	2022
Enzymology	Covalent immobilization of alcohol dehydrogenase (ADH2) from Haloferax volcanii: how to maximize activity and optimize performance of halophilic enzymes.	Alsafadi D, Paradisi F.	Mol Biotechnol	10.1007/s12033-013-9701-5	2014
	Pentose degradation in archaea: Halorhabdus species degrade D-xylose, L-arabinose and D-ribose via bacterial-type pathways.	Sutter JM, Johnsen U, Reinhardt A, Schonheit P.	Extremophiles	10.1007/s00792-020-01192-y	2020
	[An efficient genetic knockout system based on linear DNA fragment homologous recombination for halophilic archaea].	Wang XL, Jiang C, Liu JH, Liu XP.	Yi Chuan	10.16288/j.yczz.14-366	2015
	tRFs and tRNA Halves: Novel Cellular Defenders in Multiple Biological Processes.	Hou J, Li Q, Wang J, Lu W.	Curr Issues Mol Biol	10.3390/cimb44120405	2022
	From Gene to Function: A Safe Laboratory Exercise Promoting the Learning of the Central Dogma of Biology for the Undergraduate Biology Curriculum.	Tripepi M, Clear M, Bondi JL, Brunelli E, Berardi A.	J Microbiol Biol Educ	10.1128/jmbe.v21i2.2131	2020
	Influence of Origin Recognition Complex Proteins on the Copy Numbers of Three Chromosomes in Haloferax volcanii.	Ludt K, Soppa J.	J Bacteriol	10.1128/jb.00161-18	2018
Metabolism	Halorubrum pleomorphic virus-6 Membrane Fusion Is Triggered by an S-Layer Component of Its Haloarchaeal Host.	Bignon EA, Chou KR, Roine E, Tischler ND.	Viruses	10.3390/v14020254	2022
Metabolism	Haloferax volcanii Immersed Liquid Biofilms Develop Independently of Known Biofilm Machineries and Exhibit Rapid Honeycomb Pattern Formation.	Schiller H, Schulze S, Mutan Z, de Vaulx C, Runcie C, Schwartz J, Rados T, Bisson Filho AW, Pohlschroder M.	mSphere	10.1128/msphere.00976-20	2020
	Limited Cross-Complementation Between Haloferax volcanii PilB1-C1 and PilB3-C3 Paralogs.	Legerme G, Pohlschroder M.	Front Microbiol	10.3389/fmicb.2019.00700	2019
	Deletion of the Sm1 encoding motif in the lsm gene results in distinct changes in the transcriptome and enhanced swarming activity of Haloferax cells.	Maier LK, Benz J, Fischer S, Alstetter M, Jaschinski K, Hilker R, Becker A, Allers T, Soppa J, Marchfelder A.	Biochimie	10.1016/j.biochi.2015.02.023	2015
	A Small RNA Is Linking CRISPR-Cas and Zinc Transport.	Markle P, Maier LK, Maass S, Hirschfeld C, Bartel J, Becher D, Voss B, Marchfelder A.	Front Mol Biosci	10.3389/fmolb.2021.640440	2021
Proteome	Characterization of protein glycosylation in an Asgard archaeon.	Nakagawa S, Imachi H, Shimamura S, Yanaka S, Yagi H, Yagi-Utsumi M, Sakai H, Kato S, Ohkuma M, Kato K, Takai K.	BBA Adv	10.1016/j.bbadva.2024.100118	2024
Metabolism	The archaeal protein SepF is essential for cell division in Haloferax volcanii.	Nussbaum P, Gerstner M, Dingethal M, Erb C, Albers SV.	Nat Commun	10.1038/s41467-021-23686-9	2021
	Myxosortase: an intramembrane protease that sorts MYXO-CTERM proteins to the cell surface.	Guo T, Haft DH, Wall D.	mBio	10.1128/mbio.04067-24	2025
Metabolism	Haloferax volcanii as immobilised whole cell biocatalyst: new applications for halophilic systems.	Haque RU, Paradisi F, Allers T.	Appl Microbiol Biotechnol	10.1007/s00253-019-09725-y	2019
	Several One-Domain Zinc Finger µ-Proteins of Haloferax Volcanii Are Important for Stress Adaptation, Biofilm Formation, and Swarming.	Nagel C, Machulla A, Zahn S, Soppa J.	Genes (Basel)	10.3390/genes10050361	2019
	Ultrastructural insights into cellular organization, energy storage and ribosomal dynamics of an ammonia-oxidizing archaeon from oligotrophic oceans.	Zhou Y, Yan A, Yang J, He W, Guo S, Li Y, Wu J, Dai Y, Pan X, Cui D, Pereira O, Teng W, Bi R, Chen S, Fan L, Wang P, Liao Y, Qin W, Sui SF, Zhu Y, Zhang C, Liu Z.	Front Microbiol	10.3389/fmicb.2024.1367658	2024
	Transcription-coupled repair of UV damage in the halophilic archaea.	Stantial N, Dumpe J, Pietrosimone K, Baltazar F, Crowley DJ.	DNA Repair (Amst)	10.1016/j.dnarep.2016.03.007	2016
Enzymology	The LonB protease controls membrane lipids composition and is essential for viability in the extremophilic haloarchaeon Haloferax volcanii.	Cerletti M, Martinez MJ, Gimenez MI, Sastre DE, Paggi RA, De Castro RE.	Environ Microbiol	10.1111/1462-2920.12385	2014
	Composition and in situ structure of the Methanospirillum hungatei cell envelope and surface layer.	Wang H, Zhang J, Liao S, Henstra AM, Leon D, Erde J, Loo JA, Ogorzalek Loo RR, Zhou ZH, Gunsalus RP.	Sci Adv	10.1126/sciadv.adr8596	2024
	Structures of Saccharolobus solfataricus initiation complexes with leaderless mRNAs highlight archaeal features and eukaryotic proximity.	Bourgeois G, Coureux PD, Lazennec-Schurdevin C, Madru C, Gaillard T, Duchateau M, Chamot-Rooke J, Bourcier S, Mechulam Y, Schmitt E.	Nat Commun	10.1038/s41467-024-55718-5	2025
	Cell Surface Glycosylation Is Required for Efficient Mating of Haloferax volcanii.	Shalev Y, Turgeman-Grott I, Tamir A, Eichler J, Gophna U.	Front Microbiol	10.3389/fmicb.2017.01253	2017
	Accessory Gvp Proteins Form a Complex During Gas Vesicle Formation of Haloarchaea.	Volkner K, Jost A, Pfeifer F.	Front Microbiol	10.3389/fmicb.2020.610179	2020
Metabolism	Gene Expression of Haloferax volcanii on Intermediate and Abundant Sources of Fixed Nitrogen.	Hwang S, Chavarria NE, Hackley RK, Schmid AK, Maupin-Furlow JA.	Int J Mol Sci	10.3390/ijms20194784	2019
	Molecular dynamics and machine learning stratify motion-dependent activity profiles of S-layer destabilizing nanobodies.	Cecil AJ, Sogues A, Gurumurthi M, Lane KS, Remaut H, Pak AJ.	PNAS Nexus	10.1093/pnasnexus/pgae538	2024
Metabolism	Deciphering Pathways for Carotenogenesis in Haloarchaea.	Giani M, Miralles-Robledillo JM, Peiro G, Pire C, Martinez-Espinosa RM.	Molecules	10.3390/molecules25051197	2020
Metabolism	Chromosome replication origins: do we really need them?	Michel B, Bernander R.	Bioessays	10.1002/bies.201400003	2014
Metabolism	L-Arabinose degradation pathway in the haloarchaeon Haloferax volcanii involves a novel type of L-arabinose dehydrogenase.	Johnsen U, Sutter JM, Zaiss H, Schonheit P.	Extremophiles	10.1007/s00792-013-0572-2	2013
	Diversity, origin, and evolution of the ESCRT systems.	Makarova KS, Tobiasson V, Wolf YI, Lu Z, Liu Y, Zhang S, Krupovic M, Li M, Koonin EV.	mBio	10.1128/mbio.00335-24	2024
Genetics	Salty secrets of Halobacterium salinarum AD88: a new archaeal ecotype isolated from Cuatro Cienegas Basin.	Medina-Chavez NO, Rodriguez-Cruz UE, Souza V, De la Torre-Zavala S, Travisano M.	BMC Genomics	10.1186/s12864-025-11550-9	2025
Metabolism	The accessory gas vesicle protein GvpM of haloarchaea and its interaction partners during gas vesicle formation.	Tavlaridou S, Winter K, Pfeifer F.	Extremophiles	10.1007/s00792-014-0650-0	2014
	Functional Analysis of the Major Pilin Proteins of Type IV Pili in Streptococcus sanguinis CGMH010.	Chen YM, Yang YC, Shieh HR, Lin YJ, Ke WJ, Chiu CH.	Int J Mol Sci	10.3390/ijms25105402	2024
	A self-assembling surface layer flattens the cytokinetic furrow to aid cell division in an archaeon.	Foo S, Caspy I, Cezanne A, Bharat TAM, Baum B.	Proc Natl Acad Sci U S A	10.1073/pnas.2501044122	2025
	Cryo-EM resolves the structure of the archaeal dsDNA virus HFTV1 from head to tail.	Zhang DX, Isupov MN, Davies RM, Schwarzer S, McLaren M, Stuart WS, Gold VAM, Oksanen HM, Quax TEF, Daum B.	Sci Adv	10.1126/sciadv.adx1178	2025
Metabolism	A conserved type IV pilin signal peptide H-domain is critical for the post-translational regulation of flagella-dependent motility.	Esquivel RN, Pohlschroder M.	Mol Microbiol	10.1111/mmi.12673	2014
	The chromatin landscape of the histone-possessing Bacteriovorax bacteria.	Marinov GK, Doughty B, Kundaje A, Greenleaf WJ.	Genome Res	10.1101/gr.279418.124	2025
Metabolism	Add salt, add sugar: N-glycosylation in Haloferax volcanii.	Kaminski L, Naparstek S, Kandiba L, Cohen-Rosenzweig C, Arbiv A, Konrad Z, Eichler J.	Biochem Soc Trans	10.1042/bst20120142	2013
Enzymology	Effect of organic solvents on the activity and stability of halophilic alcohol dehydrogenase (ADH2) from Haloferax volcanii.	Alsafadi D, Paradisi F.	Extremophiles	10.1007/s00792-012-0498-0	2013
	Growth Phase Dependent Cell Shape of Haloarcula.	Schwarzer S, Rodriguez-Franco M, Oksanen HM, Quax TEF.	Microorganisms	10.3390/microorganisms9020231	2021
Phylogeny	Evaluating the efficiency of 16S-ITS-23S operon sequencing for species level resolution in microbial communities.	Srinivas M, Walsh CJ, Crispie F, O'Sullivan O, Cotter PD, van Sinderen D, Kenny JG.	Sci Rep	10.1038/s41598-024-83410-7	2025
	Splicing Endonuclease Is an Important Player in rRNA and tRNA Maturation in Archaea.	Schwarz TS, Berkemer SJ, Bernhart SH, Weiss M, Ferreira-Cerca S, Stadler PF, Marchfelder A.	Front Microbiol	10.3389/fmicb.2020.594838	2020
Metabolism	A Cobalamin Activity-Based Probe Enables Microbial Cell Growth and Finds New Cobalamin-Protein Interactions across Domains.	Rosnow JJ, Hwang S, Killinger BJ, Kim YM, Moore RJ, Lindemann SR, Maupin-Furlow JA, Wright AT.	Appl Environ Microbiol	10.1128/aem.00955-18	2018
Pathogenicity	A halocin-H4 mutant Haloferax mediterranei strain retains the ability to inhibit growth of other halophilic archaea.	Naor A, Yair Y, Gophna U.	Extremophiles	10.1007/s00792-013-0579-8	2013
	Diversity and Potential Multifunctionality of Archaeal CetZ Tubulin-like Cytoskeletal Proteins.	Brown HJ, Duggin IG.	Biomolecules	10.3390/biom13010134	2023
Genetics	Characterization of promoters in archaeal genomes based on DNA structural parameters.	Martinez GS, Sarkar S, Kumar A, Perez-Rueda E, de Avila E Silva S.	Microbiologyopen	10.1002/mbo3.1230	2021
	Characterizing the DNA Methyltransferases of Haloferax volcanii via Bioinformatics, Gene Deletion, and SMRT Sequencing.	Ouellette M, Gogarten JP, Lajoie J, Makkay AM, Papke RT.	Genes (Basel)	10.3390/genes9030129	2018
	Identification of RNA 3´ ends and termination sites in Haloferax volcanii.	Berkemer SJ, Maier LK, Amman F, Bernhart SH, Wortz J, Markle P, Pfeiffer F, Stadler PF, Marchfelder A.	RNA Biol	10.1080/15476286.2020.1723328	2020
Genetics	Diversity of DNA Replication in the Archaea.	Ausiannikava D, Allers T.	Genes (Basel)	10.3390/genes8020056	2017
Metabolism	Haloferax volcanii archaeosortase is required for motility, mating, and C-terminal processing of the S-layer glycoprotein.	Abdul Halim MF, Pfeiffer F, Zou J, Frisch A, Haft D, Wu S, Tolic N, Brewer H, Payne SH, Pasa-Tolic L, Pohlschroder M.	Mol Microbiol	10.1111/mmi.12248	2013
	TrmB Family Transcription Factor as a Thiol-Based Regulator of Oxidative Stress Response.	Mondragon P, Hwang S, Kasirajan L, Oyetoro R, Nasthas A, Winters E, Couto-Rodriguez RL, Schmid A, Maupin-Furlow JA.	mBio	10.1128/mbio.00633-22	2022
Metabolism	Engineering substrate promiscuity in halophilic alcohol dehydrogenase (HvADH2) by in silico design.	Cassidy J, Bruen L, Rosini E, Molla G, Pollegioni L, Paradisi F.	PLoS One	10.1371/journal.pone.0187482	2017
Metabolism	Transfer RNA-Derived Small Non-Coding RNA: Dual Regulator of Protein Synthesis.	Kim HK.	Mol Cells	10.14348/molcells.2019.0214	2019
Metabolism	Effect of an overproduction of accessory Gvp proteins on gas vesicle formation in Haloferax volcanii.	Tavlaridou S, Faist K, Weitzel K, Pfeifer F.	Extremophiles	10.1007/s00792-013-0515-y	2013
	Molecular Factors of Hypochlorite Tolerance in the Hypersaline Archaeon Haloferax volcanii.	Gomez M, Leung W, Dantuluri S, Pillai A, Gani Z, Hwang S, McMillan LJ, Kiljunen S, Savilahti H, Maupin-Furlow JA.	Genes (Basel)	10.3390/genes9110562	2018
	Requirements for a successful defence reaction by the CRISPR-Cas subtype I-B system.	Stoll B, Maier LK, Lange SJ, Brendel J, Fischer S, Backofen R, Marchfelder A.	Biochem Soc Trans	10.1042/bst20130098	2013
	Characterization of Copy Number Control of Two Haloferax volcanii Replication Origins Using Deletion Mutants and Haloarchaeal Artificial Chromosomes.	Maurer S, Ludt K, Soppa J.	J Bacteriol	10.1128/jb.00517-17	2018
Transcriptome	Sequencing accuracy and systematic errors of nanopore direct RNA sequencing.	Liu-Wei W, van der Toorn W, Bohn P, Holzer M, Smyth RP, von Kleist M.	BMC Genomics	10.1186/s12864-024-10440-w	2024
Enzymology	Heterologous overexpression, purification and characterisation of an alcohol dehydrogenase (ADH2) from Halobacterium sp. NRC-1.	Liliensiek AK, Cassidy J, Gucciardo G, Whitely C, Paradisi F.	Mol Biotechnol	10.1007/s12033-013-9666-4	2013
Metabolism	Use of GFP-GvpE fusions to quantify the GvpD-mediated reduction of the transcriptional activator GvpE in haloarchaea.	Schmidt I, Pfeifer F.	Arch Microbiol	10.1007/s00203-013-0885-7	2013
	Structure of the two-component S-layer of the archaeon Sulfolobus acidocaldarius.	Gambelli L, McLaren M, Conners R, Sanders K, Gaines MC, Clark L, Gold VAM, Kattnig D, Sikora M, Hanus C, Isupov MN, Daum B.	Elife	10.7554/elife.84617	2024
	A transfer RNA methyltransferase with an unusual domain composition catalyzes 2'-O-methylation at position 6 in tRNA.	Matsuda T, Yamagami R, Ihara A, Suzuki T, Hirata A, Hori H.	Nucleic Acids Res	10.1093/nar/gkaf579	2025
Proteome	N-linked protein glycosylation in Nanobdellati (formerly DPANN) archaea and their hosts.	Nakagawa S, Sakai HD, Shimamura S, Takamatsu Y, Kato S, Yagi H, Yanaka S, Yagi-Utsumi M, Kurosawa N, Ohkuma M, Kato K, Takai K.	J Bacteriol	10.1128/jb.00205-24	2024
Enzymology	Enhancing recombinant protein solubility with ubiquitin-like small archeal modifying protein fusion partners.	Varga S, Pathare GR, Baka E, Boicu M, Kriszt B, Szekacs A, Zinzula L, Kukolya J, Nagy I.	J Microbiol Methods	10.1016/j.mimet.2015.08.017	2015
	Salactin, a dynamically unstable actin homolog in Haloarchaea.	Zheng J, Mallon J, Lammers A, Rados T, Litschel T, Moody ERR, Ramirez-Diaz DA, Schmid A, Williams TA, Bisson-Filho AW, Garner E.	mBio	10.1128/mbio.02272-23	2023
Enzymology	A comparison of two novel alcohol dehydrogenase enzymes (ADH1 and ADH2) from the extreme halophile Haloferax volcanii.	Timpson LM, Liliensiek AK, Alsafadi D, Cassidy J, Sharkey MA, Liddell S, Allers T, Paradisi F.	Appl Microbiol Biotechnol	10.1007/s00253-012-4074-4	2013
	Disruption-induced changes in syntrophic propionate and acetate oxidation: flocculation, cell proximity, and microbial activity.	Weng N, Najafabadi HN, Westerholm M.	Biotechnol Biofuels Bioprod	10.1186/s13068-025-02644-3	2025
Metabolism	Cell division in the archaeon Haloferax volcanii relies on two FtsZ proteins with distinct functions in division ring assembly and constriction.	Liao Y, Ithurbide S, Evenhuis C, Lowe J, Duggin IG.	Nat Microbiol	10.1038/s41564-021-00894-z	2021
	DRJAMM Is Involved in the Oxidative Resistance in Deinococcus radiodurans.	Cai J, Pan C, Zhao Y, Xu H, Tian B, Wang L, Hua Y.	Front Microbiol	10.3389/fmicb.2021.756867	2021
	The cell biology of archaea.	van Wolferen M, Pulschen AA, Baum B, Gribaldo S, Albers SV.	Nat Microbiol	10.1038/s41564-022-01215-8	2022
	Data in support of global role of the membrane protease LonB in Archaea: Potential protease targets revealed by quantitative proteome analysis of a lonB mutant in Haloferax volcanii.	Cerletti M, Paggi RA, Ramallo Guevara C, Poetsch A, De Castro RE.	Data Brief	10.1016/j.dib.2015.04.013	2015
Pathogenicity	A type IV pili-mediated mutualism between two co-resident temperate archaeal viruses and their host.	Xiang J, Sonani RR, Wang Y, Chen Z, Xiong W, Chen J, Li S, An K, Wang Y, Liu Y, Kreutzberger MAB, Krupovic M, Egelman EH, Du S, Chen X.	Cell Rep	10.1016/j.celrep.2025.115873	2025
Pathogenicity	The Microbial Anti-Inflammatory Molecule (MAM) is a key protein processed and exported to Faecalibacterium duncaniae envelope.	Vilela Rodrigues T, Marthey S, Auger S, Lima de Jesus L, Henry C, Pechoux C, Arteni A, Martin V, Langella P, de Castro Soares S, Andre G, Azevedo VAC, Chatel JM.	Gut Microbes	10.1080/19490976.2025.2519695	2025
	The salty tango of brine composition and UV photochemistry effects on Halobacterium salinarum cell envelope biosignature preservation.	Bourmance L, Marie A, Puppo R, Brule S, Schaeffer P, Toupet M, Nitsche R, Elsaesser A, Kish A.	Commun Biol	10.1038/s42003-025-08007-w	2025
	Deciphering archaeal glycolipids of an extremely halophilic archaeon of the genus Halobellus by MALDI-TOF/MS.	Lobasso S, Perez-Davo A, Vitale R, Sanchez MM, Corcelli A.	Chem Phys Lipids	10.1016/j.chemphyslip.2014.11.002	2015
	CdrS Is a Global Transcriptional Regulator Influencing Cell Division in Haloferax volcanii.	Liao Y, Vogel V, Hauber S, Bartel J, Alkhnbashi OS, Maass S, Schwarz TS, Backofen R, Becher D, Duggin IG, Marchfelder A.	mBio	10.1128/mbio.01416-21	2021
	Characterization of the transcriptome of Haloferax volcanii, grown under four different conditions, with mixed RNA-Seq.	Laass S, Monzon VA, Kliemt J, Hammelmann M, Pfeiffer F, Forstner KU, Soppa J.	PLoS One	10.1371/journal.pone.0215986	2019
Metabolism	Cu-NirK from Haloferax mediterranei as an example of metalloprotein maturation and exportation via Tat system.	Esclapez J, Zafrilla B, Martinez-Espinosa RM, Bonete MJ.	Biochim Biophys Acta	10.1016/j.bbapap.2013.03.002	2013
	Interaction of the gas vesicle proteins GvpA, GvpC, GvpN, and GvpO of Halobacterium salinarum.	Jost A, Pfeifer F.	Front Microbiol	10.3389/fmicb.2022.971917	2022
Metabolism	Secretion of Tat-dependent halolysin SptA capable of autocatalytic activation and its relation to haloarchaeal growth.	Du X, Li M, Tang W, Zhang Y, Zhang L, Wang J, Li T, Tang B, Tang XF.	Mol Microbiol	10.1111/mmi.12955	2015
Genetics	Evolution of Genome Architecture in Archaea: Spontaneous Generation of a New Chromosome in Haloferax volcanii.	Ausiannikava D, Mitchell L, Marriott H, Smith V, Hawkins M, Makarova KS, Koonin EV, Nieduszynski CA, Allers T.	Mol Biol Evol	10.1093/molbev/msy075	2018
Enzymology	Prospects for robust biocatalysis: engineering of novel specificity in a halophilic amino acid dehydrogenase.	Munawar N, Engel PC.	Extremophiles	10.1007/s00792-012-0491-7	2013
Enzymology	Resurrection of Ancestral Malate Dehydrogenases Reveals the Evolutionary History of Halobacterial Proteins: Deciphering Gene Trajectories and Changes in Biochemical Properties.	Blanquart S, Groussin M, Le Roy A, Szollosi GJ, Girard E, Franzetti B, Gouy M, Madern D.	Mol Biol Evol	10.1093/molbev/msab146	2021
	Polyploidy in archaea and bacteria: about desiccation resistance, giant cell size, long-term survival, enforcement by a eukaryotic host and additional aspects.	Soppa J.	J Mol Microbiol Biotechnol	10.1159/000368855	2014
	Cellular differentiation into hyphae and spores in halophilic archaea.	Tang SK, Zhi XY, Zhang Y, Makarova KS, Liu BB, Zheng GS, Zhang ZP, Zheng HJ, Wolf YI, Zhao YR, Jiang SH, Chen XM, Li EY, Zhang T, Chen PR, Feng YZ, Xiang MX, Lin ZQ, Shi JH, Chang C, Zhang X, Li R, Lou K, Wang Y, Chang L, Yin M, Yang LL, Gao HY, Zhang ZK, Tao TS, Guan TW, He FC, Lu YH, Cui HL, Koonin EV, Zhao GP, Xu P.	Nat Commun	10.1038/s41467-023-37389-w	2023
Metabolism	tRNA-like elements in Haloferax volcanii.	Holzle A, Stoll B, Schnattinger T, Schoning U, Tjaden B, Marchfelder A.	Biochimie	10.1016/j.biochi.2011.12.002	2012
Metabolism	Comprehensive Bioinformatics Analysis of the Biodiversity of Lsm Proteins in the Archaea Domain.	Paya G, Bautista V, Camacho M, Esclapez J, Bonete MJ.	Microorganisms	10.3390/microorganisms11051196	2023
Enzymology	Halophilic archaea produce wax esters and use an alternative fatty acyl-coenzyme A reductase for precursor synthesis.	Grossi V, Cuny P, Militon C, Witwinowski J, Eddhif B, Sylvi L, Nowakowski M, Kosta A, Antheaume I, Cornil J, Dubrac S, Kende J, Gribaldo S, Borrel G.	ISME J	10.1093/ismejo/wraf035	2025
	A versatile cis-acting element reporter system to study the function, maturation and stability of ribosomal RNA mutants in archaea.	Juttner M, Weiss M, Ostheimer N, Reglin C, Kern M, Knuppel R, Ferreira-Cerca S.	Nucleic Acids Res	10.1093/nar/gkz1156	2020
	Biogenesis of DNA-carrying extracellular vesicles by the dominant human gut methanogenic archaeon	Baquero D, Borrel G, Gazi A, Martin-Gallausiaux C, Cvirkaite-Krupovic V, Commere P, Pende N, Tachon S, Sartori-Rupp A, Douche T, Matondo M, Gribaldo S, Krupovic M.	Nat Commun		2025
	The Novel Halovirus Hardycor1, and the Presence of Active (Induced) Proviruses in Four Haloarchaea.	Dyall-Smith M, Pfeiffer F, Chiang PW, Tang SL.	Genes (Basel)	10.3390/genes12020149	2021
	Unusual cell surfaces, pili, and archaella of Thermoplasmatales archaea.	Gaines MC, Isupov MN, McLaren M, Haque RU, Recalde A, Bargiela R, Gold VAM, Albers SV, Golyshin PN, Golyshina OV, Daum B.	ISME J	10.1093/ismejo/wraf176	2025
	Phenotyping in the archaea: optimization of growth parameters and analysis of mutants of Haloferax volcanii.	Jantzer K, Zerulla K, Soppa J.	FEMS Microbiol Lett	10.1111/j.1574-6968.2011.02341.x	2011
Genetics	Specific DNA binding of archaeal histones HMfA and HMfB.	Erkelens AM, Henneman B, van der Valk RA, Kirolos NCS, Dame RT.	Front Microbiol	10.3389/fmicb.2023.1166608	2023
	Comparative survival analysis of Deinococcus radiodurans and the haloarchaea Natrialba magadii and Haloferax volcanii exposed to vacuum ultraviolet irradiation.	Abrevaya XC, Paulino-Lima IG, Galante D, Rodrigues F, Mauas PJ, Corton E, Lage Cde A.	Astrobiology	10.1089/ast.2011.0607	2011
Enzymology	The only exoribonuclease present in Haloferax volcanii has an unique response to temperature changes.	Matos RG, Lopez-Vinas E, Gomez-Puertas P, Arraiano CM.	Biochim Biophys Acta	10.1016/j.bbagen.2012.06.009	2012
	Genome-wide transcriptional response to silver stress in extremely halophilic archaeon Haloferax alexandrinus DSM 27206^T.	Buda DM, Szekeres E, Tudoran LB, Esclapez J, Banciu HL.	BMC Microbiol	10.1186/s12866-023-03133-z	2023
	A Synthetic Riboswitch to Regulate Haloarchaeal Gene Expression.	Born J, Weitzel K, Suess B, Pfeifer F.	Front Microbiol	10.3389/fmicb.2021.696181	2021
Metabolism	mRNA-specific translation regulation by a ribosome-associated ncRNA in Haloferax volcanii.	Wyss L, Waser M, Gebetsberger J, Zywicki M, Polacek N.	Sci Rep	10.1038/s41598-018-30332-w	2018
Genetics	Genomic analysis of heavy metal-resistant Halobacterium salinarum isolated from Sfax solar saltern sediments.	Baati H, Siala M, Azri C, Ammar E, Dunlap C, Trigui M.	Extremophiles	10.1007/s00792-022-01273-0	2022
	Low species barriers in halophilic archaea and the formation of recombinant hybrids.	Naor A, Lapierre P, Mevarech M, Papke RT, Gophna U.	Curr Biol	10.1016/j.cub.2012.05.056	2012
Transcriptome	Transcriptional Landscape and Regulatory Roles of Small Noncoding RNAs in the Oxidative Stress Response of the Haloarchaeon Haloferax volcanii.	Gelsinger DR, DiRuggiero J.	J Bacteriol	10.1128/jb.00779-17	2018
	A dual promoter region with overlapping activator sequences drives the expression of gas vesicle protein genes in haloarchaea.	Marschaus L, Pfeifer F.	Microbiology (Reading)	10.1099/mic.0.060178-0	2012
	Identification, Antioxidant Capacity, and Matrix Metallopeptidase 9 (MMP-9) In Silico Inhibition of Haloarchaeal Carotenoids from Natronococcus sp. and Halorubrum tebenquichense.	Delgado-Garcia M, Gomez-Secundino O, Rodriguez JA, Mateos-Diaz JC, Muller-Santos M, Aguilar CN, Camacho-Ruiz RM.	Microorganisms	10.3390/microorganisms11092344	2023
Transcriptome	Transcriptomic profiling of haloarchaeal denitrification through RNA-Seq analysis.	Miralles-Robledillo JM, Martinez-Espinosa RM, Pire C.	Appl Environ Microbiol	10.1128/aem.00571-24	2024
Transcriptome	The Primary Antisense Transcriptome of Halobacterium salinarum NRC-1.	de Almeida JPP, Vencio RZN, Lorenzetti APR, Caten FT, Gomes-Filho JV, Koide T.	Genes (Basel)	10.3390/genes10040280	2019
Biotechnology	Haloferax volcanii for biotechnology applications: challenges, current state and perspectives.	Haque RU, Paradisi F, Allers T.	Appl Microbiol Biotechnol	10.1007/s00253-019-10314-2	2020
Genetics	Gene conversion results in the equalization of genome copies in the polyploid haloarchaeon Haloferax volcanii.	Lange C, Zerulla K, Breuert S, Soppa J.	Mol Microbiol	10.1111/j.1365-2958.2011.07600.x	2011
	The switch complex ArlCDE connects the chemotaxis system and the archaellum.	Li Z, Rodriguez-Franco M, Albers SV, Quax TEF.	Mol Microbiol	10.1111/mmi.14527	2020
	Bioinformatic prediction and experimental verification of sRNAs in the haloarchaeon Haloferax volcanii.	Babski J, Tjaden B, Voss B, Jellen-Ritter A, Marchfelder A, Hess WR, Soppa J.	RNA Biol	10.4161/rna.8.5.16039	2011
Metabolism	Comprehensive glycoproteomics shines new light on the complexity and extent of glycosylation in archaea.	Schulze S, Pfeiffer F, Garcia BA, Pohlschroder M.	PLoS Biol	10.1371/journal.pbio.3001277	2021
	Characterization of multicomponent antioxidants from Haloferax alexandrinus GUSF-1 (KF796625).	Alvares JJ, Furtado IJ.	3 Biotech	10.1007/s13205-020-02584-9	2021
	Microbial dynamics, chemical profile, and bioactive potential of diverse Egyptian marine environments from archaeological wood to soda lake.	Hegazy GE, Moawad MN, Othman SS, Soliman NA, Abeer E A, Oraby H, Abdel-Fattah YR.	Sci Rep	10.1038/s41598-024-70411-9	2024
	Ribosome-Associated ncRNAs (rancRNAs) Adjust Translation and Shape Proteomes.	Pecoraro V, Rosina A, Polacek N.	Noncoding RNA	10.3390/ncrna8020022	2022
	Distinct filament morphology and membrane tethering features of the dual FtsZ paralogs in Odinarchaeota.	Kumari J, Uthaman A, Bose S, Kundu A, Sharma V, Dutta S, Dhar A, Roy S, Srinivasan R, Pande S, Vinothkumar KR, Gayathri P, Palani S.	EMBO J	10.1038/s44318-025-00529-7	2025
	Adaptation induced by self-targeting in a type I-B CRISPR-Cas system.	Stachler AE, Wortz J, Alkhnbashi OS, Turgeman-Grott I, Smith R, Allers T, Backofen R, Gophna U, Marchfelder A.	J Biol Chem	10.1074/jbc.ra120.014030	2020
Phylogeny	Mapping of active replication origins in vivo in thaum- and euryarchaeal replicons.	Pelve EA, Martens-Habbena W, Stahl DA, Bernander R.	Mol Microbiol	10.1111/mmi.12382	2013
Metabolism	N-Glycosylation Is Important for Proper Haloferax volcanii S-Layer Stability and Function.	Tamir A, Eichler J.	Appl Environ Microbiol	10.1128/aem.03152-16	2017
Metabolism	Lipid Anchoring of Archaeosortase Substrates and Midcell Growth in Haloarchaea.	Abdul-Halim MF, Schulze S, DiLucido A, Pfeiffer F, Bisson Filho AW, Pohlschroder M.	mBio	10.1128/mbio.00349-20	2020
	Archaeal replicative primase mediates DNA double-strand break repair.	Xiong D, Li Z, Qi W, Wang S, Huang J, Zhang N, Zhang Z, Huang L.	Nucleic Acids Res	10.1093/nar/gkaf322	2025
Metabolism	Regulatory RNAs in Haloferax volcanii.	Fischer S, Benz J, Spath B, Jellen-Ritter A, Heyer R, Dorr M, Maier LK, Menzel-Hobeck C, Lehr M, Jantzer K, Babski J, Soppa J, Marchfelder A.	Biochem Soc Trans	10.1042/bst0390159	2011
	Members of the class Candidatus Ordosarchaeia imply an alternative evolutionary scenario from methanogens to haloarchaea.	Zhao D, Zhang S, Chen J, Zhao J, An P, Xiang H.	ISME J	10.1093/ismejo/wrad033	2024
Metabolism	Multiplex quantitative SILAC for analysis of archaeal proteomes: a case study of oxidative stress responses.	McMillan LJ, Hwang S, Farah RE, Koh J, Chen S, Maupin-Furlow JA.	Environ Microbiol	10.1111/1462-2920.14014	2018
	A new age in structural S-layer biology: Experimental and in silico milestones.	Grill-Walcher S, Schaffer C.	J Biol Chem	10.1016/j.jbc.2025.110205	2025
	Disentangling a metabolic cross-feeding in a halophilic archaea-bacteria consortium.	Medina-Chavez NO, Torres-Cerda A, Chacon JM, Harcombe WR, De la Torre-Zavala S, Travisano M.	Front Microbiol	10.3389/fmicb.2023.1276438	2023
Metabolism	N-linked glycosylation in Archaea: two paths to the same glycan.	Guerry P.	Mol Microbiol	10.1111/j.1365-2958.2011.07782.x	2011
Genetics	Biochemical and Taxonomic Characterization of Novel Haloarchaeal Strains and Purification of the Recombinant Halotolerant alpha-Amylase Discovered in the Isolate.	Verma DK, Vasudeva G, Sidhu C, Pinnaka AK, Prasad SE, Thakur KG.	Front Microbiol	10.3389/fmicb.2020.02082	2020
Metabolism	Crystal structure of ubiquitin-like small archaeal modifier protein 1 (SAMP1) from Haloferax volcanii.	Jeong YJ, Jeong BC, Song HK.	Biochem Biophys Res Commun	10.1016/j.bbrc.2011.01.004	2011
	Halobacterium salinarum NRC-1 Sustains Voltage Production in a Dual-Chambered Closed Microbial Fuel Cell.	Goncalves RO, Salehi A, Publico M, Nyende J, Nadarajah N, Ghoreyshi S, Shastri P.	ScientificWorldJournal	10.1155/2022/3885745	2022
Genetics	A Micrarchaeon Isolate Is Covered by a Proteinaceous S-Layer.	Gfrerer S, Winkler D, Novion Ducassou J, Coute Y, Rachel R, Gescher J.	Appl Environ Microbiol	10.1128/aem.01553-21	2022
Genetics	Characterization of an archaeal virus-host system reveals massive genomic rearrangements in a laboratory strain.	Mercier C, Thies D, Zhong L, Raftery MJ, Erdmann S.	Front Microbiol	10.3389/fmicb.2023.1274068	2023
Metabolism	Growth phenotype analysis of heme synthetic enzymes in a halophilic archaeon, Haloferax volcanii.	Kosugi N, Araki T, Fujita J, Tanaka S, Fujiwara T.	PLoS One	10.1371/journal.pone.0189913	2017
Metabolism	Different glycosyltransferases are involved in lipid glycosylation and protein N-glycosylation in the halophilic archaeon Haloferax volcanii.	Naparstek S, Vinagradov E, Eichler J.	Arch Microbiol	10.1007/s00203-010-0581-9	2010
Metabolism	Hot and sweet: protein glycosylation in Crenarchaeota.	Meyer BH, Albers SV.	Biochem Soc Trans	10.1042/bst20120296	2013
Metabolism	The archaeal Xpf/Mus81/FANCM homolog Hef and the Holliday junction resolvase Hjc define alternative pathways that are essential for cell viability in Haloferax volcanii.	Lestini R, Duan Z, Allers T.	DNA Repair (Amst)	10.1016/j.dnarep.2010.06.012	2010
	Perturbed N-glycosylation of Halobacterium salinarum archaellum filaments leads to filament bundling and compromised cell motility.	Sofer S, Vershinin Z, Mashni L, Zalk R, Shahar A, Eichler J, Grossman-Haham I.	Nat Commun	10.1038/s41467-024-50277-1	2024
	Detection and Quantitation of Small Proteins Using Mass Spectrometry.	Franco PHC, Zeinert R, Meier-Credo J, Storz G, Langer JD.	Mol Cell Proteomics	10.1016/j.mcpro.2025.101052	2025
Genetics	Transcriptional landscape of the cell cycle in a model thermoacidophilic archaeon reveals similarities to eukaryotes.	Gomez-Raya-Vilanova MV, Teuliere J, Medvedeva S, Dai Y, Corel E, Lopez P, Lapointe FJ, Bhattacharya D, Haraoui LP, Turc E, Monot M, Cvirkaite-Krupovic V, Bapteste E, Krupovic M.	Nat Commun	10.1038/s41467-025-60613-8	2025
	Widespread divergent transcription from bacterial and archaeal promoters is a consequence of DNA-sequence symmetry.	Warman EA, Forrest D, Guest T, Haycocks JJRJ, Wade JT, Grainger DC.	Nat Microbiol	10.1038/s41564-021-00898-9	2021
	The ring of confidence: a haloarchaeal CRISPR/Cas system.	Maier LK, Stoll B, Brendel J, Fischer S, Pfeiffer F, Dyall-Smith M, Marchfelder A.	Biochem Soc Trans	10.1042/bst20120263	2013
Genetics	High tolerance to self-targeting of the genome by the endogenous CRISPR-Cas system in an archaeon.	Stachler AE, Turgeman-Grott I, Shtifman-Segal E, Allers T, Marchfelder A, Gophna U.	Nucleic Acids Res	10.1093/nar/gkx150	2017
	A novel structural maintenance of chromosomes (SMC)-related protein family specific to Archaea.	Yoshinaga M, Nakayama T, Inagaki Y.	Front Microbiol	10.3389/fmicb.2022.913088	2022
	Revisiting N-glycosylation in Halobacterium salinarum: Characterizing a dolichol phosphate- and glycoprotein-bound tetrasaccharide.	Vershinin Z, Zaretsky M, Guan Z, Eichler J.	Glycobiology	10.1093/glycob/cwab080	2021
Metabolism	Archaeal Inorganic Pyrophosphatase Displays Robust Activity under High-Salt Conditions and in Organic Solvents.	McMillan LJ, Hepowit NL, Maupin-Furlow JA.	Appl Environ Microbiol	10.1128/aem.03055-15	2016
Metabolism	GlpR Is a Direct Transcriptional Repressor of Fructose Metabolic Genes in Haloferax volcanii.	Martin JH, Sherwood Rawls K, Chan JC, Hwang S, Martinez-Pastor M, McMillan LJ, Prunetti L, Schmid AK, Maupin-Furlow JA.	J Bacteriol	10.1128/jb.00244-18	2018
	The Newly Sequenced Genome of Pisum sativum Is Replete with Potential G-Quadruplex-Forming Sequences-Implications for Evolution and Biological Regulation.	Dobrovolna M, Bohalova N, Peska V, Wang J, Luo Y, Bartas M, Volna A, Mergny JL, Brazda V.	Int J Mol Sci	10.3390/ijms23158482	2022
	Effect of Mutations in GvpJ and GvpM on Gas Vesicle Formation of Halobacterium salinarum.	Jost A, Knitsch R, Volkner K, Pfeifer F.	Front Microbiol	10.3389/fmicb.2021.794240	2021
Genetics	Comparative Genomic Insights into Chemoreceptor Diversity and Habitat Adaptation of Archaea.	Cha G, Liu Y, Yang Q, Bai L, Cheng L, Fan W.	Appl Environ Microbiol	10.1128/aem.01574-22	2022
Metabolism	Deciphering a pathway of Halobacterium salinarum N-glycosylation.	Kandiba L, Eichler J.	Microbiologyopen	10.1002/mbo3.215	2015
Genetics	Coupling chromosome organization to genome segregation in Archaea.	Kabli AF, Ng IW, Read N, Pal P, Reimann J, Tran NT, Albers SV, Le TBK, Barilla D.	Nat Commun	10.1038/s41467-025-61997-3	2025
Proteome	Ionic strength-dependent conformations of a ubiquitin-like small archaeal modifier protein (SAMP1) from Haloferax volcanii.	Ye K, Liao S, Zhang W, Fan K, Zhang X, Zhang J, Xu C, Tu X.	Protein Sci	10.1002/pro.2302	2013
Enzymology	Biochemical and Kinetic Characterization of the Glucose-6-Phosphate Dehydrogenase from Helicobacter pylori Strain 29CaP.	Ortiz-Ramirez P, Hernandez-Ochoa B, Ortega-Cuellar D, Gonzalez-Valdez A, Martinez-Rosas V, Morales-Luna L, Arreguin-Espinosa R, Castillo-Rodriguez RA, Canseco-Avila LM, Cardenas-Rodriguez N, Perez de la Cruz V, Montiel-Gonzalez AM, Gomez-Chavez F, Gomez-Manzo S.	Microorganisms	10.3390/microorganisms10071359	2022
Genetics	An improved CRISPR and CRISPR interference (CRISPRi) toolkit for engineering the model methanogenic archaeon Methanococcus maripaludis.	Du Q, Wei Y, Zhang L, Ren D, Gao J, Dong X, Bai L, Li J.	Microb Cell Fact	10.1186/s12934-024-02492-0	2024
Metabolism	N-glycosylation in Archaea: on the coordinated actions of Haloferax volcanii AglF and AglM.	Yurist-Doutsch S, Magidovich H, Ventura VV, Hitchen PG, Dell A, Eichler J.	Mol Microbiol	10.1111/j.1365-2958.2009.07045.x	2010
Metabolism	AglP is a S-adenosyl-L-methionine-dependent methyltransferase that participates in the N-glycosylation pathway of Haloferax volcanii.	Magidovich H, Yurist-Doutsch S, Konrad Z, Ventura VV, Dell A, Hitchen PG, Eichler J.	Mol Microbiol	10.1111/j.1365-2958.2010.07090.x	2010
	Microbial electroactive biofilms dominated by Geoalkalibacter spp. from a highly saline-alkaline environment.	Yadav S, Patil SA.	NPJ Biofilms Microbiomes	10.1038/s41522-020-00147-7	2020
	A New Record for Microbial Perchlorate Tolerance: Fungal Growth in NaClO₄ Brines and its Implications for Putative Life on Mars.	Heinz J, Krahn T, Schulze-Makuch D.	Life (Basel)	10.3390/life10050053	2020
	Isolation and characterization of a main porin from the outer membrane of Salinibacter ruber.	Farci D, Cocco E, Tanas M, Kirkpatrick J, Maxia A, Tamburini E, Schroder WP, Piano D.	J Bioenerg Biomembr	10.1007/s10863-022-09950-7	2022
	Snapshots of archaeal DNA replication and repair in living cells using super-resolution imaging.	Delpech F, Collien Y, Mahou P, Beaurepaire E, Myllykallio H, Lestini R.	Nucleic Acids Res	10.1093/nar/gky829	2018
	The Overlooked Microbiome-Considering Archaea and Eukaryotes Using Multiplex Nanopore-16S-/18S-rDNA-Sequencing: A Technical Report Focusing on Nasopharyngeal Microbiomes.	Baehren C, Pembaur A, Weil PP, Wewers N, Schult F, Wirth S, Postberg J, Aydin M.	Int J Mol Sci	10.3390/ijms24021426	2023
	The extremophile Picrophilus torridus carries a DNA adenine methylase M.PtoI that is part of a Type I restriction-modification system.	Gulati P, Singh A, Goel M, Saha S.	Front Microbiol	10.3389/fmicb.2023.1126750	2023
	Role of VapBC4 toxin-antitoxin system of Sulfolobus acidocaldarius in heat stress adaptation.	Bhowmick A, Recalde A, Bhattacharyya C, Banerjee A, Das J, Rodriguez-Cruz UE, Albers S-V, Ghosh A.	mBio	10.1128/mbio.02753-24	2024
Metabolism	A 2-oxoacid dehydrogenase complex of Haloferax volcanii is essential for growth on isoleucine but not on other branched-chain amino acids.	Sisignano M, Morbitzer D, Gatgens J, Oldiges M, Soppa J.	Microbiology (Reading)	10.1099/mic.0.033449-0	2010
	Hypersaline Lake Urmia: a potential hotspot for microbial genomic variation.	Kheiri R, Mehrshad M, Pourbabaee AA, Ventosa A, Amoozegar MA.	Sci Rep	10.1038/s41598-023-27429-2	2023
	Multimeric structure of a subfamily III haloalkane dehalogenase-like enzyme solved by combination of cryo-EM and x-ray crystallography.	Chmelova K, Gao T, Polak M, Schenkmayerova A, Croll TI, Shaikh TR, Skarupova J, Chaloupkova R, Diederichs K, Read RJ, Damborsky J, Novacek J, Marek M.	Protein Sci	10.1002/pro.4751	2023
Genetics	Haloferax volcanii-a model archaeon for studying DNA replication and repair.	Perez-Arnaiz P, Dattani A, Smith V, Allers T.	Open Biol	10.1098/rsob.200293	2020
Metabolism	SufS protein from Haloferax volcanii involved in Fe-S cluster assembly in haloarchaea.	Zafrilla B, Martinez-Espinosa RM, Esclapez J, Perez-Pomares F, Bonete MJ.	Biochim Biophys Acta	10.1016/j.bbapap.2010.03.001	2010
	Genome-wide DNA methylation analysis of Haloferax volcanii H26 and identification of DNA methyltransferase related PD-(D/E)XK nuclease family protein HVO_A0006.	Ouellette M, Jackson L, Chimileski S, Papke RT.	Front Microbiol	10.3389/fmicb.2015.00251	2015
Genetics	Dissecting the Arginine and Lysine Biosynthetic Pathways and Their Relationship in Haloarchaeon Natrinema gari J7-2 via Endogenous CRISPR-Cas System-Based Genome Editing.	Wu Y, Zhang J, Wang B, Zhang Y, Li H, Liu Y, Yin J, He D, Luo H, Gan F, Tang B, Tang XF.	Microbiol Spectr	10.1128/spectrum.00288-23	2023
Enzymology	Overexpression in a non-native halophilic host and biotechnological potential of NAD+-dependent glutamate dehydrogenase from Halobacterium salinarum strain NRC-36014.	Munawar N, Engel PC.	Extremophiles	10.1007/s00792-012-0446-z	2012
Metabolism	RadB acts in homologous recombination in the archaeon Haloferax volcanii, consistent with a role as recombination mediator.	Wardell K, Haldenby S, Jones N, Liddell S, Ngo GHP, Allers T.	DNA Repair (Amst)	10.1016/j.dnarep.2017.04.005	2017
Genetics	A Well-Conserved Archaeal B-Family Polymerase Functions as an Extender in Translesion Synthesis.	Feng X, Zhang B, Gao Z, Xu R, Liu X, Ishino S, Feng M, Shen Y, Ishino Y, She Q.	mBio	10.1128/mbio.02659-21	2022
Metabolism	Key Enzymes of the Semiphosphorylative Entner-Doudoroff Pathway in the Haloarchaeon Haloferax volcanii: Characterization of Glucose Dehydrogenase, Gluconate Dehydratase, and 2-Keto-3-Deoxy-6-Phosphogluconate Aldolase.	Sutter JM, Tastensen JB, Johnsen U, Soppa J, Schonheit P.	J Bacteriol	10.1128/jb.00286-16	2016
	PerR functions as a redox-sensing transcription factor regulating metal homeostasis in the thermoacidophilic archaeon Saccharolobus islandicus REY15A.	Zhang X, Wu P, Bai R, Gan Q, Yang Y, Li H, Ni J, Huang Q, Shen Y.	Nucleic Acids Res	10.1093/nar/gkae1263	2025
	Analysis of Lsm Protein-Mediated Regulation in the Haloarchaeon Haloferax mediterranei.	Paya G, Bautista V, Pastor-Soler S, Camacho M, Esclapez J, Bonete MJ.	Int J Mol Sci	10.3390/ijms25010580	2024
	Structural and functional adaptation of Haloferax volcanii TFEalpha/beta.	Blombach F, Ausiannikava D, Figueiredo AM, Soloviev Z, Prentice T, Zhang M, Zhou N, Thalassinos K, Allers T, Werner F.	Nucleic Acids Res	10.1093/nar/gkx1302	2018
Metabolism	Salt-dependent regulation of archaellins in Haloarcula marismortui.	Syutkin AS, van Wolferen M, Surin AK, Albers SV, Pyatibratov MG, Fedorov OV, Quax TEF.	Microbiologyopen	10.1002/mbo3.718	2019
	Haloterrigena sp. Strain SGH1, a Bacterioruberin-Rich, Perchlorate-Tolerant Halophilic Archaeon Isolated From Halite Microbial Communities, Atacama Desert, Chile.	Flores N, Hoyos S, Venegas M, Galetovic A, Zuniga LM, Fabrega F, Paredes B, Salazar-Ardiles C, Vilo C, Ascaso C, Wierzchos J, Souza-Egipsy V, Araya JE, Batista-Garcia RA, Gomez-Silva B.	Front Microbiol	10.3389/fmicb.2020.00324	2020
	Biofilms formed by the archaeon Haloferax volcanii exhibit cellular differentiation and social motility, and facilitate horizontal gene transfer.	Chimileski S, Franklin MJ, Papke RT.	BMC Biol	10.1186/s12915-014-0065-5	2014
	Characterization of Polyhydroxybutyrate, PHB, Synthesized by Newly Isolated Haloarchaea Halolamina spp.	Hagagy N, Saddiq AA, Tag HM, Selim S, AbdElgawad H, Martinez-Espinosa RM.	Molecules	10.3390/molecules27217366	2022
	Explainable artificial intelligence as a reliable annotator of archaeal promoter regions.	Sganzerla Martinez G, Perez-Rueda E, Kumar A, Sarkar S, de Avila E Silva S.	Sci Rep	10.1038/s41598-023-28571-7	2023
	Pyridoxal 5'-phosphate synthesis and salvage in Bacteria and Archaea: predicting pathway variant distributions and holes.	Denise R, Babor J, Gerlt JA, de Crecy-Lagard V.	Microb Genom	10.1099/mgen.0.000926	2023
Metabolism	Ribosome profiling in archaea reveals leaderless translation, novel translational initiation sites, and ribosome pausing at single codon resolution.	Gelsinger DR, Dallon E, Reddy R, Mohammad F, Buskirk AR, DiRuggiero J.	Nucleic Acids Res	10.1093/nar/gkaa304	2020
	Screening of a Haloferax volcanii Transposon Library Reveals Novel Motility and Adhesion Mutants.	Legerme G, Yang E, Esquivel RN, Kiljunen S, Savilahti H, Pohlschroder M.	Life (Basel)	10.3390/life6040041	2016
	Archaea-based microbial fuel cell operating at high ionic strength conditions.	Abrevaya XC, Sacco N, Mauas PJ, Corton E.	Extremophiles	10.1007/s00792-011-0394-z	2011
Metabolism	Small RNAs of the halophilic archaeon Haloferax volcanii.	Soppa J, Straub J, Brenneis M, Jellen-Ritter A, Heyer R, Fischer S, Granzow M, Voss B, Hess WR, Tjaden B, Marchfelder A.	Biochem Soc Trans	10.1042/bst0370133	2009
	Optimized generation of vectors for the construction of Haloferax volcanii deletion mutants.	Hammelmann M, Soppa J.	J Microbiol Methods	10.1016/j.mimet.2008.05.029	2008
	Toward Time-Resolved Analysis of RNA Metabolism in Archaea Using 4-Thiouracil.	Knuppel R, Kuttenberger C, Ferreira-Cerca S.	Front Microbiol	10.3389/fmicb.2017.00286	2017
Enzymology	NMR-derived folate-bound structure of dihydrofolate reductase 1 from the halophile Haloferax volcanii.	Boroujerdi AF, Young JK.	Biopolymers	10.1002/bip.21096	2009
Metabolism	Characterisation of a solvent-tolerant haloarchaeal (R)-selective transaminase isolated from a Triassic period salt mine.	Kelly SA, Magill DJ, Megaw J, Skvortsov T, Allers T, McGrath JW, Allen CCR, Moody TS, Gilmore BF.	Appl Microbiol Biotechnol	10.1007/s00253-019-09806-y	2019
Metabolism	Nonsense suppression in archaea.	Bhattacharya A, Kohrer C, Mandal D, RajBhandary UL.	Proc Natl Acad Sci U S A	10.1073/pnas.1501558112	2015
Metabolism	tRNA Modification Profiles and Codon-Decoding Strategies in Methanocaldococcus jannaschii.	Yu N, Jora M, Solivio B, Thakur P, Acevedo-Rocha CG, Randau L, de Crecy-Lagard V, Addepalli B, Limbach PA.	J Bacteriol	10.1128/jb.00690-18	2019
Metabolism	Biosynthesis and function of tRNA modifications in Archaea.	Phillips G, de Crecy-Lagard V.	Curr Opin Microbiol	10.1016/j.mib.2011.03.001	2011
Enzymology	Characterization of alcohol dehydrogenase (ADH12) from Haloarcula marismortui, an extreme halophile from the Dead Sea.	Timpson LM, Alsafadi D, Mac Donnchadha C, Liddell S, Sharkey MA, Paradisi F.	Extremophiles	10.1007/s00792-011-0405-0	2012
Metabolism	Opsin-Mediated Inhibition of Bacterioruberin Synthesis in Halophilic Archaea.	Peck RF, Plesa AM, Graham SM, Angelini DR, Shaw EL.	J Bacteriol	10.1128/jb.00303-17	2017
	Ionic strength-dependent conformations of a ubiquitin-like small archaeal modifier protein (SAMP2) from Haloferax volcanii.	Liao S, Zhang W, Fan K, Ye K, Zhang X, Zhang J, Xu C, Tu X.	Sci Rep	10.1038/srep02136	2013
Genetics	Novel Genes Involved in Resistance to Both Ultraviolet Radiation and Perchlorate From the Metagenomes of Hypersaline Environments.	Lamprecht-Grandio M, Cortesao M, Mirete S, de la Camara MB, de Figueras CG, Perez-Pantoja D, White JJ, Farias ME, Rossello-Mora R, Gonzalez-Pastor JE.	Front Microbiol	10.3389/fmicb.2020.00453	2020
	Characterization of a Haloferax volcanii member of the enolase superfamily: deletion mutant construction, expression analysis, and transcriptome comparison.	Dambeck M, Soppa J.	Arch Microbiol	10.1007/s00203-008-0379-1	2008
Metabolism	Tantalizing evidence for caspase-like protein expression and activity in the cellular stress response of Archaea.	Bidle KA, Haramaty L, Baggett N, Nannen J, Bidle KD.	Environ Microbiol	10.1111/j.1462-2920.2010.02157.x	2010
	Highly efficient and simple SSPER and rrPCR approaches for the accurate site-directed mutagenesis of large and small plasmids.	Jia H, Couto-Rodriguez R, Johnson S, Medina S, Novillo B, Huynh P, Kim M, Cooper C, Michalik M, Siew B, Turesson E, Maupin-Furlow JA.	N Biotechnol	10.1016/j.nbt.2022.08.004	2022
	Engineering and expressing circular RNAs via tRNA splicing.	Noto JJ, Schmidt CA, Matera AG.	RNA Biol	10.1080/15476286.2017.1317911	2017
	tRNAmodpred: A computational method for predicting posttranscriptional modifications in tRNAs.	Machnicka MA, Dunin-Horkawicz S, de Crecy-Lagard V, Bujnicki JM.	Methods	10.1016/j.ymeth.2016.03.013	2016
	Structural insights into the mechanism of archaellar rotational switching.	Altegoer F, Quax TEF, Weiland P, Nussbaum P, Giammarinaro PI, Patro M, Li Z, Oesterhelt D, Grininger M, Albers SV, Bange G.	Nat Commun	10.1038/s41467-022-30358-9	2022
Genetics	Communication between DNA polymerases and Replication Protein A within the archaeal replisome.	Martinez-Carranza M, Vialle L, Madru C, Cordier F, Tekpinar AD, Haouz A, Legrand P, Le Meur RA, England P, Dulermo R, Guijarro JI, Henneke G, Sauguet L.	Nat Commun	10.1038/s41467-024-55365-w	2024
	N-glycosylation in Haloferax volcanii: adjusting the sweetness.	Eichler J, Arbiv A, Cohen-Rosenzweig C, Kaminski L, Kandiba L, Konrad Z.	Front Microbiol	10.3389/fmicb.2013.00403	2013
	A genetic investigation of the KEOPS complex in halophilic Archaea.	Naor A, Thiaville PC, Altman-Price N, Cohen-Or I, Allers T, de Crecy-Lagard V, Gophna U.	PLoS One	10.1371/journal.pone.0043013	2012
	Small RNAs in haloarchaea: identification, differential expression and biological function.	Straub J, Brenneis M, Jellen-Ritter A, Heyer R, Soppa J, Marchfelder A.	RNA Biol	10.4161/rna.6.3.8357	2009
Metabolism	AglF, aglG and aglI, novel members of a gene island involved in the N-glycosylation of the Haloferax volcanii S-layer glycoprotein.	Yurist-Doutsch S, Abu-Qarn M, Battaglia F, Morris HR, Hitchen PG, Dell A, Eichler J.	Mol Microbiol	10.1111/j.1365-2958.2008.06352.x	2008
	An archaeal histone-like protein regulates gene expression in response to salt stress.	Sakrikar S, Schmid AK.	Nucleic Acids Res	10.1093/nar/gkab1175	2021
	Laboratory Activity to Promote Student Understanding of UV Mutagenesis and DNA Repair.	Kouassi JE, Waldron I, Tripepi M, Pohlschroder M.	J Microbiol Biol Educ	10.1128/jmbe.v18i1.1202	2017
	Post-transcriptional regulation of redox homeostasis by the small RNA SHOxi in haloarchaea.	Gelsinger DR, Reddy R, Whittington K, Debic S, DiRuggiero J.	RNA Biol	10.1080/15476286.2021.1874717	2021
Enzymology	Reexploring 5-methoxyindole-2-carboxylic acid (MICA) as a potential antidiabetic agent.	Yan LJ.	Diabetes Metab Syndr Obes	10.2147/dmso.s166485	2018
	Divergent Roles of RPA Homologs of the Model Archaeon Halobacterium salinarum in Survival of DNA Damage.	Evans JJ, Gygli PE, McCaskill J, DeVeaux LC.	Genes (Basel)	10.3390/genes9040223	2018
Metabolism	Specificity of archaeal caspase activity in the extreme halophile Haloferax volcanii.	Seth-Pasricha M, Bidle KA, Bidle KD.	Environ Microbiol Rep	10.1111/1758-2229.12010	2013
	Haloferax volcanii, as a Novel Tool for Producing Mammalian Olfactory Receptors Embedded in Archaeal Lipid Bilayer.	Lobasso S, Vitale R, Lopalco P, Corcelli A.	Life (Basel)	10.3390/life5010770	2015
	Enhancing Open Modification Searches via a Combined Approach Facilitated by Ursgal.	Schulze S, Igiraneza AB, Kosters M, Leufken J, Leidel SA, Garcia BA, Fufezan C, Pohlschroder M.	J Proteome Res	10.1021/acs.jproteome.0c00799	2021
Metabolism	Conserved active site cysteine residue of archaeal THI4 homolog is essential for thiamine biosynthesis in Haloferax volcanii.	Hwang S, Cordova B, Chavarria N, Elbanna D, McHugh S, Rojas J, Pfeiffer F, Maupin-Furlow JA.	BMC Microbiol	10.1186/s12866-014-0260-0	2014
	Pervasive acquisition of CRISPR memory driven by inter-species mating of archaea can limit gene transfer and influence speciation.	Turgeman-Grott I, Joseph S, Marton S, Eizenshtein K, Naor A, Soucy SM, Stachler AE, Shalev Y, Zarkor M, Reshef L, Altman-Price N, Marchfelder A, Gophna U.	Nat Microbiol	10.1038/s41564-018-0302-8	2019
Metabolism	Rhodanese-Like Domain Protein UbaC and Its Role in Ubiquitin-Like Protein Modification and Sulfur Mobilization in Archaea.	Hepowit NL, Maupin-Furlow JA.	J Bacteriol	10.1128/jb.00254-19	2019
Metabolism	Haloferax volcanii twin-arginine translocation substates include secreted soluble, C-terminally anchored and lipoproteins.	Gimenez MI, Dilks K, Pohlschroder M.	Mol Microbiol	10.1111/j.1365-2958.2007.06034.x	2007
Metabolism	Architecture and modular assembly of Sulfolobus S-layers revealed by electron cryotomography.	Gambelli L, Meyer BH, McLaren M, Sanders K, Quax TEF, Gold VAM, Albers SV, Daum B.	Proc Natl Acad Sci U S A	10.1073/pnas.1911262116	2019
Metabolism	Division plane placement in pleomorphic archaea is dynamically coupled to cell shape.	Walsh JC, Angstmann CN, Bisson-Filho AW, Garner EC, Duggin IG, Curmi PMG.	Mol Microbiol	10.1111/mmi.14316	2019
	Cell cycle dependent coordination of surface layer biogenesis in Caulobacter crescentus.	Herdman M, Isbilir B, von Kugelgen A, Schulze U, Wainman A, Bharat TAM.	Nat Commun	10.1038/s41467-024-47529-5	2024
Metabolism	Glucose inhibits the formation of gas vesicles in Haloferax volcanii transformants.	Hechler T, Frech M, Pfeifer F.	Environ Microbiol	10.1111/j.1462-2920.2007.01426.x	2008
Enzymology	Kinetic folding of Haloferax volcanii and Escherichia coli dihydrofolate reductases: haloadaptation by unfolded state destabilization at high ionic strength.	Gloss LM, Topping TB, Binder AK, Lohman JR.	J Mol Biol	10.1016/j.jmb.2007.12.056	2008
	Characterization of a tightly controlled promoter of the halophilic archaeon Haloferax volcanii and its use in the analysis of the essential cct1 gene.	Large A, Stamme C, Lange C, Duan Z, Allers T, Soppa J, Lund PA.	Mol Microbiol	10.1111/j.1365-2958.2007.05980.x	2007
	Chromosome architecture in an archaeal species naturally lacking structural maintenance of chromosomes proteins.	Badel C, Bell SD.	Nat Microbiol	10.1038/s41564-023-01540-6	2024
Metabolism	The 2-oxoacid dehydrogenase multienzyme complex of Haloferax volcanii.	Al-Mailem DM, Hough DW, Danson MJ.	Extremophiles	10.1007/s00792-007-0091-0	2008
Metabolism	The information transfer system of halophilic archaea.	Capes MD, Coker JA, Gessler R, Grinblat-Huse V, DasSarma SL, Jacob CG, Kim JM, DasSarma P, DasSarma S.	Plasmid	10.1016/j.plasmid.2010.11.005	2011
Metabolism	Anaerobiosis inhibits gas vesicle formation in halophilic Archaea.	Hechler T, Pfeifer F.	Mol Microbiol	10.1111/j.1365-2958.2008.06517.x	2009
Genetics	DNA replication origins in archaea.	Wu Z, Liu J, Yang H, Xiang H.	Front Microbiol	10.3389/fmicb.2014.00179	2014
Metabolism	Haloferax volcanii AglB and AglD are involved in N-glycosylation of the S-layer glycoprotein and proper assembly of the surface layer.	Abu-Qarn M, Yurist-Doutsch S, Giordano A, Trauner A, Morris HR, Hitchen P, Medalia O, Dell A, Eichler J.	J Mol Biol	10.1016/j.jmb.2007.10.042	2007
Enzymology	Three 2-oxoacid dehydrogenase operons in Haloferax volcanii: expression, deletion mutants and evolution.	van Ooyen J, Soppa J.	Microbiology (Reading)	10.1099/mic.0.2007/008508-0	2007
Metabolism	Overexpression and purification of halophilic proteins in Haloferax volcanii.	Allers T.	Bioeng Bugs	10.4161/bbug.1.4.11794	2010
Genetics	Structural and functional studies of PCNA from African swine fever virus.	Shao Z, Yang J, Gao Y, Zhang Y, Zhao X, Shao Q, Zhang W, Cao C, Liu H, Gan J.	J Virol	10.1128/jvi.00748-23	2023
	Functional and Molecular Characterization of the Halomicrobium sp. IBSBa Inulosucrase.	Abaramak G, Porras-Dominguez JR, Janse van Rensburg HC, Lescrinier E, Toksoy Oner E, Kirtel O, Van den Ende W.	Microorganisms	10.3390/microorganisms9040749	2021
Proteome	Deciphering the folding code of collagens.	Malcor JD, Ferruz N, Romero-Romero S, Dhingra S, Sagar V, Jalan AA.	Nat Commun	10.1038/s41467-024-54046-y	2025
	Archaeal membrane-associated proteases: insights on Haloferax volcanii and other haloarchaea.	Gimenez MI, Cerletti M, De Castro RE.	Front Microbiol	10.3389/fmicb.2015.00039	2015
	Protein biogenesis in Archaea: addressing translation initiation using an in vitro protein synthesis system for Haloferax volcanii.	Ring G, Londei P, Eichler J.	FEMS Microbiol Lett	10.1111/j.1574-6968.2007.00649.x	2007
	The role of Cas8 in type I CRISPR interference.	Cass SD, Haas KA, Stoll B, Alkhnbashi OS, Sharma K, Urlaub H, Backofen R, Marchfelder A, Bolt EL.	Biosci Rep	10.1042/bsr20150043	2015
	Survival, metabolic activity, and ultrastructural damages of Antarctic black fungus in perchlorates media.	Cassaro A, Pacelli C, Onofri S.	Front Microbiol	10.3389/fmicb.2022.992077	2022
	The Adaptive Immune System of Haloferax volcanii.	Maier LK, Dyall-Smith M, Marchfelder A.	Life (Basel)	10.3390/life5010521	2015
Metabolism	Permuting the PGF Signature Motif Blocks both Archaeosortase-Dependent C-Terminal Cleavage and Prenyl Lipid Attachment for the Haloferax volcanii S-Layer Glycoprotein.	Abdul Halim MF, Karch KR, Zhou Y, Haft DH, Garcia BA, Pohlschroder M.	J Bacteriol	10.1128/jb.00849-15	2015
Enzymology	Peptide synthesis catalysed by a haloalkaliphilic serine protease from the archaeon Natrialba magadii (Nep).	Ruiz DM, Iannuci NB, Cascone O, De Castro RE.	Lett Appl Microbiol	10.1111/j.1472-765x.2010.02955.x	2010
Pathogenicity	Effect of proteasome inhibitor clasto-lactacystin-beta-lactone on the proteome of the haloarchaeon Haloferax volcanii.	Kirkland PA, Reuter CJ, Maupin-Furlow JA.	Microbiology (Reading)	10.1099/mic.0.2007/005769-0	2007
Metabolism	Identification of Haloferax volcanii Pilin N-Glycans with Diverse Roles in Pilus Biosynthesis, Adhesion, and Microcolony Formation.	Esquivel RN, Schulze S, Xu R, Hippler M, Pohlschroder M.	J Biol Chem	10.1074/jbc.m115.693556	2016
Metabolism	Genetic Study of Four Candidate Holliday Junction Processing Proteins in the Thermophilic Crenarchaeon Sulfolobus acidocaldarius.	Matsuda R, Suzuki S, Kurosawa N.	Int J Mol Sci	10.3390/ijms23020707	2022
	Succinyl-CoA:Mesaconate CoA-Transferase and Mesaconyl-CoA Hydratase, Enzymes of the Methylaspartate Cycle in Haloarcula hispanica.	Borjian F, Johnsen U, Schonheit P, Berg IA.	Front Microbiol	10.3389/fmicb.2017.01683	2017
	An old friend with a new face: tRNA-derived small RNAs with big regulatory potential in cancer biology.	Di Fazio A, Gullerova M.	Br J Cancer	10.1038/s41416-023-02191-4	2023
Transcriptome	Transcriptome-Wide Analysis of Stationary Phase Small ncRNAs in E. coli.	Raad N, Luidalepp H, Fasnacht M, Polacek N.	Int J Mol Sci	10.3390/ijms22041703	2021
Enzymology	Discovery of a putative acetoin dehydrogenase complex in the hyperthermophilic archaeon Sulfolobus solfataricus.	Payne KA, Hough DW, Danson MJ.	FEBS Lett	10.1016/j.febslet.2010.02.037	2010
	Transcriptional linkage of Haloferax volcanii proteasomal genes with non-proteasomal gene neighbours including RNase P, MOSC domain and SAM-methyltransferase homologues.	Gil MA, Sherwood KE, Maupin-Furlow JA.	Microbiology (Reading)	10.1099/mic.0.2007/008177-0	2007
	Lipid modification gives rise to two distinct Haloferax volcanii S-layer glycoprotein populations.	Kandiba L, Guan Z, Eichler J.	Biochim Biophys Acta	10.1016/j.bbamem.2012.11.023	2013
Enzymology	AglM and VNG1048G, Two Haloarchaeal UDP-Glucose Dehydrogenases, Show Different Salt-Related Behaviors.	Kandiba L, Eichler J.	Life (Basel)	10.3390/life6030031	2016
Metabolism	Interaction of two strongly divergent archaellins stabilizes the structure of the Halorubrum archaellum.	Pyatibratov MG, Syutkin AS, Quax TEF, Melnik TN, Papke RT, Gogarten JP, Kireev II, Surin AK, Beznosov SN, Galeva AV, Fedorov OV.	Microbiologyopen	10.1002/mbo3.1047	2020
Transcriptome	Differences in gene expression patterns between cultured and natural Haloquadratum walsbyi ecotypes.	Rosselli R, Lopez-Perez M, Martin-Cuadrado AB, Rodriguez-Valera F, Bolhuis H.	Front Microbiol	10.3389/fmicb.2022.1044446	2022
Metabolism	Two archaeal tRNase Z enzymes: similar but different.	Spath B, Schubert S, Lieberoth A, Settele F, Schutz S, Fischer S, Marchfelder A.	Arch Microbiol	10.1007/s00203-008-0368-4	2008
Metabolism	Cloning, recombinant production and crystallographic structure of Proliferating Cell Nuclear Antigen from radioresistant archaeon Thermococcus gammatolerans.	Venancio-Landeros AA, Rudino-Pinera E, Cardona-Felix CS.	Biochem Biophys Rep	10.1016/j.bbrep.2016.08.004	2016
	Influence of N-Glycosylation on Virus-Host Interactions in Halorubrum lacusprofundi.	Gebhard LJ, Vershinin Z, Alarcon-Schumacher T, Eichler J, Erdmann S.	Viruses	10.3390/v15071469	2023
	Accurate Prediction of the Statistics of Repetitions in Random Sequences: A Case Study in Archaea Genomes.	Regnier M, Chassignet P.	Front Bioeng Biotechnol	10.3389/fbioe.2016.00035	2016
	Hypersaline organic wastewater treatment: Biotechnological advances and engineering challenges.	Zhang YQ, Han JL, Cheng HY, Wang HC, Liu TJ, Liang B, Wang AJ.	Environ Sci Ecotechnol	10.1016/j.ese.2025.100542	2025
	The effects of extremes of pH on the growth and transcriptomic profiles of three haloarchaea.	Moran-Reyna A, Coker JA.	F1000Res	10.12688/f1000research.4789.2	2014
	Functional Prediction and Assignment of Methanobrevibacter ruminantium M1 Operome Using a Combined Bioinformatics Approach.	Bharathi M, Senthil Kumar N, Chellapandi P.	Front Genet	10.3389/fgene.2020.593990	2020
	Exploring the Molecular Machinery of Denitrification in Haloferax mediterranei Through Proteomics.	Torregrosa-Crespo J, Pire C, Richardson DJ, Martinez-Espinosa RM.	Front Microbiol	10.3389/fmicb.2020.605859	2020
Metabolism	HMG-CoA reductase is regulated by salinity at the level of transcription in Haloferax volcanii.	Bidle KA, Hanson TE, Howell K, Nannen J.	Extremophiles	10.1007/s00792-006-0008-3	2007
	Isolation, characterization and exploring biotechnological potential of halophilic archaea from salterns of western India.	Singh A, Singh AK.	3 Biotech	10.1007/s13205-017-1072-3	2018
	Endonucleolytic processing plays a critical role in the maturation of ribosomal RNA in Methanococcus maripaludis.	Qi L, Liu H, Gao J, Deng K, Wang X, Dong X, Li J.	RNA Biol	10.1080/15476286.2023.2258035	2023
Metabolism	ThiN as a Versatile Domain of Transcriptional Repressors and Catalytic Enzymes of Thiamine Biosynthesis.	Hwang S, Cordova B, Abdo M, Pfeiffer F, Maupin-Furlow JA.	J Bacteriol	10.1128/jb.00810-16	2017
	A Haloarchaeal Small Regulatory RNA (sRNA) Is Essential for Rapid Adaptation to Phosphate Starvation Conditions.	Kliemt J, Jaschinski K, Soppa J.	Front Microbiol	10.3389/fmicb.2019.01219	2019
Transcriptome	Chromatin is an ancient innovation conserved between Archaea and Eukarya.	Ammar R, Torti D, Tsui K, Gebbia M, Durbic T, Bader GD, Giaever G, Nislow C.	Elife	10.7554/elife.00078	2012
Metabolism	The Halophile protein database.	Sharma N, Farooqi MS, Chaturvedi KK, Lal SB, Grover M, Rai A, Pandey P.	Database (Oxford)	10.1093/database/bau114	2014
Metabolism	Interaction of transcription activator GvpE with TATA-box-binding proteins of Halobacterium salinarum.	Teufel K, Pfeifer F.	Arch Microbiol	10.1007/s00203-009-0537-0	2010
Metabolism	The haloarchaeal chromosome replication machinery.	MacNeill SA.	Biochem Soc Trans	10.1042/bst0370108	2009
Enzymology	Haloferax volcanii PitA: an example of functional interaction between the Pfam chlorite dismutase and antibiotic biosynthesis monooxygenase families?	Bab-Dinitz E, Shmuely H, Maupin-Furlow J, Eichler J, Shaanan B.	Bioinformatics	10.1093/bioinformatics/btk043	2006
	Sulfated archaeal glycolipid archaeosomes as a safe and effective vaccine adjuvant for induction of cell-mediated immunity.	McCluskie MJ, Deschatelets L, Krishnan L.	Hum Vaccin Immunother	10.1080/21645515.2017.1316912	2017
	The tRNA discriminator base defines the mutual orthogonality of two distinct pyrrolysyl-tRNA synthetase/tRNAPyl pairs in the same organism.	Zhang H, Gong X, Zhao Q, Mukai T, Vargas-Rodriguez O, Zhang H, Zhang Y, Wassel P, Amikura K, Maupin-Furlow J, Ren Y, Xu X, Wolf YI, Makarova KS, Koonin EV, Shen Y, Soll D, Fu X.	Nucleic Acids Res	10.1093/nar/gkac271	2022
Enzymology	Evolutionary insights into Trm112-methyltransferase holoenzymes involved in translation between archaea and eukaryotes.	van Tran N, Muller L, Ross RL, Lestini R, Letoquart J, Ulryck N, Limbach PA, de Crecy-Lagard V, Cianferani S, Graille M.	Nucleic Acids Res	10.1093/nar/gky638	2018
Metabolism	Anaerobic Growth of Haloarchaeon Haloferax volcanii by Denitrification Is Controlled by the Transcription Regulator NarO.	Hattori T, Shiba H, Ashiki K, Araki T, Nagashima YK, Yoshimatsu K, Fujiwara T.	J Bacteriol	10.1128/jb.00833-15	2016
Metabolism	Extracellular DNA metabolism in Haloferax volcanii.	Chimileski S, Dolas K, Naor A, Gophna U, Papke RT.	Front Microbiol	10.3389/fmicb.2014.00057	2014
Enzymology	Haloferax volcanii N-glycosylation: delineating the pathway of dTDP-rhamnose biosynthesis.	Kaminski L, Eichler J.	PLoS One	10.1371/journal.pone.0097441	2014
Metabolism	Protein N-glycosylation in Archaea: defining Haloferax volcanii genes involved in S-layer glycoprotein glycosylation.	Abu-Qarn M, Eichler J.	Mol Microbiol	10.1111/j.1365-2958.2006.05252.x	2006
Metabolism	Proteome targets of ubiquitin-like samp1ylation are associated with sulfur metabolism and oxidative stress in Haloferax volcanii.	Dantuluri S, Wu Y, Hepowit NL, Chen H, Chen S, Maupin-Furlow JA.	Proteomics	10.1002/pmic.201500153	2016
	All three chaperonin genes in the archaeon Haloferax volcanii are individually dispensable.	Kapatai G, Large A, Benesch JL, Robinson CV, Carrascosa JL, Valpuesta JM, Gowrinathan P, Lund PA.	Mol Microbiol	10.1111/j.1365-2958.2006.05324.x	2006
	Efficacy of signal peptide predictors in identifying signal peptides in the experimental secretome of Picrophilous torridus, a thermoacidophilic archaeon.	Singhal N, Garg A, Singh N, Gulati P, Kumar M, Goel M.	PLoS One	10.1371/journal.pone.0255826	2021
Enzymology	ATP- and NAD+-dependent DNA ligases share an essential function in the halophilic archaeon Haloferax volcanii.	Zhao A, Gray FC, MacNeill SA.	Mol Microbiol	10.1111/j.1365-2958.2005.04975.x	2006
	Dissection of Functional Domains of Orc1-2, the Archaeal Global DNA Damage-Responsive Regulator.	Liu X, Sun M, Xu R, Shen Y, Huang Q, Feng X, She Q.	Int J Mol Sci	10.3390/ijms232314609	2022
	Complete atomic structure of a native archaeal cell surface.	von Kugelgen A, Alva V, Bharat TAM.	Cell Rep	10.1016/j.celrep.2021.110052	2021
Metabolism	AglQ is a novel component of the Haloferax volcanii N-glycosylation pathway.	Arbiv A, Yurist-Doutsch S, Guan Z, Eichler J.	PLoS One	10.1371/journal.pone.0081782	2013
	Antioxidant, Antimicrobial, and Bioactive Potential of Two New Haloarchaeal Strains Isolated from Odiel Salterns (Southwest Spain).	Gomez-Villegas P, Vigara J, Vila M, Varela J, Barreira L, Leon R.	Biology (Basel)	10.3390/biology9090298	2020
	Comparative CRISPR type III-based knockdown of essential genes in hyperthermophilic Sulfolobales and the evasion of lethal gene silencing.	Zink IA, Fouqueau T, Tarrason Risa G, Werner F, Baum B, Blasi U, Schleper C.	RNA Biol	10.1080/15476286.2020.1813411	2021
	Comparative patterns of modified nucleotides in individual tRNA species from a mesophilic and two thermophilic archaea.	Wolff P, Villette C, Zumsteg J, Heintz D, Antoine L, Chane-Woon-Ming B, Droogmans L, Grosjean H, Westhof E.	RNA	10.1261/rna.077537.120	2020
	High-Temperature Live-Cell Imaging of Cytokinesis, Cell Motility, and Cell-Cell Interactions in the Thermoacidophilic Crenarchaeon Sulfolobus acidocaldarius.	Charles-Orszag A, Lord SJ, Mullins RD.	Front Microbiol	10.3389/fmicb.2021.707124	2021
Enzymology	Complete reversal of coenzyme specificity of isocitrate dehydrogenase from Haloferax volcanii.	Rodriguez-Arnedo A, Camacho M, Llorca F, Bonete MJ.	Protein J	10.1007/s10930-005-6746-8	2005
	Synthesis and degradation of the cyclic dinucleotide messenger c-di-AMP in the hyperthermophilic archaeon Pyrococcus yayanosii.	Jin Z, Song D, Wang WW, Feng L, Li ZX, Chen HF, Xiao X, Liu XP.	Protein Sci	10.1002/pro.4829	2023
Metabolism	Two distinct N-glycosylation pathways process the Haloferax volcanii S-layer glycoprotein upon changes in environmental salinity.	Kaminski L, Guan Z, Yurist-Doutsch S, Eichler J.	mBio	10.1128/mbio.00716-13	2013
Enzymology	Insights from the salt bridge analysis of malate dehydrogenase from H. salinarum and E.coli.	Bandyopadhyay AK, Islam RNU, Mitra D, Banerjee S, Yasmeen S, Goswami A.	Bioinformation	10.6026/97320630015095	2019
Enzymology	An unusual glycerol-3-phosphate dehydrogenase in Sulfolobus acidocaldarius elucidates the diversity of glycerol metabolism across Archaea.	Schmerling C, Schroeder C, Zhou X, Bost J, Wassmer B, Ninck S, Busche T, Montero L, Kaschani F, Schmitz OJ, Kalinowski J, Kaiser M, Albers SV, Brasen C, Siebers B.	Commun Biol	10.1038/s42003-025-07953-9	2025
Metabolism	A tRNA-derived fragment competes with mRNA for ribosome binding and regulates translation during stress.	Gebetsberger J, Wyss L, Mleczko AM, Reuther J, Polacek N.	RNA Biol	10.1080/15476286.2016.1257470	2017
Metabolism	Role of RadA and DNA Polymerases in Recombination-Associated DNA Synthesis in Hyperthermophilic Archaea.	Hogrel G, Lu Y, Alexandre N, Bosse A, Dulermo R, Ishino S, Ishino Y, Flament D.	Biomolecules	10.3390/biom10071045	2020
Enzymology	Improvement of two-dimensional gel electrophoresis proteome maps of the haloarchaeon Haloferax volcanii.	Karadzic IM, Maupin-Furlow JA.	Proteomics	10.1002/pmic.200400950	2005
	Positioning of the Motility Machinery in Halophilic Archaea.	Li Z, Kinosita Y, Rodriguez-Franco M, Nussbaum P, Braun F, Delpech F, Quax TEF, Albers SV.	mBio	10.1128/mbio.00377-19	2019
	Impact of a homing intein on recombination frequency and organismal fitness.	Naor A, Altman-Price N, Soucy SM, Green AG, Mitiagin Y, Turgeman-Grott I, Davidovich N, Gogarten JP, Gophna U.	Proc Natl Acad Sci U S A	10.1073/pnas.1606416113	2016
Enzymology	[Analysis of promoter sequence and its activity of homologues gene rad25 of eukaryotes from halophilic archaea].	Zhu JY, Hu YH, Liu J, Huang YP, Shen P.	Wei Sheng Wu Xue Bao		2006
Metabolism	Chaperones and protein folding in the archaea.	Large AT, Goldberg MD, Lund PA.	Biochem Soc Trans	10.1042/bst0370046	2009
	Exploring D-xylose oxidation in Saccharomyces cerevisiae through the Weimberg pathway.	Wasserstrom L, Portugal-Nunes D, Almqvist H, Sandstrom AG, Liden G, Gorwa-Grauslund MF.	AMB Express	10.1186/s13568-018-0564-9	2018
Enzymology	Trizol-based method for sample preparation and isoelectric focusing of halophilic proteins.	Kirkland PA, Busby J, Stevens S, Maupin-Furlow JA.	Anal Biochem	10.1016/j.ab.2006.01.017	2006
Metabolism	Conditional Alternative Protein Splicing Promoted by Inteins from Haloquadratum walsbyi.	Yalala VR, Lynch AK, Mills KV.	Biochemistry	10.1021/acs.biochem.1c00788	2022
Metabolism	Identification in Haloferax volcanii of phosphomevalonate decarboxylase and isopentenyl phosphate kinase as catalysts of the terminal enzyme reactions in an archaeal alternate mevalonate pathway.	Vannice JC, Skaff DA, Keightley A, Addo JK, Wyckoff GJ, Miziorko HM.	J Bacteriol	10.1128/jb.01230-13	2014
Metabolism	Structural and biochemical properties of an extreme 'salt-loving' proteasome activating nucleotidase from the archaeon Haloferax volcanii.	Prunetti L, Reuter CJ, Hepowit NL, Wu Y, Barrueto L, Miranda HV, Kelly K, Maupin-Furlow JA.	Extremophiles	10.1007/s00792-013-0615-8	2014
	Chemical cross-linking, mass spectrometry, and in silico modeling of proteasomal 20S core particles of the haloarchaeon Haloferax volcanii.	Karadzic I, Maupin-Furlow J, Humbard M, Prunetti L, Singh P, Goodlett DR.	Proteomics	10.1002/pmic.201100260	2012
Phylogeny	Generation and phenotyping of a collection of sRNA gene deletion mutants of the haloarchaeon Haloferax volcanii.	Jaschinski K, Babski J, Lehr M, Burmester A, Benz J, Heyer R, Dorr M, Marchfelder A, Soppa J.	PLoS One	10.1371/journal.pone.0090763	2014
	Dynamics of the Synechococcus elongatus cytoskeletal GTPase FtsZ yields mechanistic and evolutionary insight into cyanobacterial and chloroplast FtsZs.	Porter KJ, Cao L, Osteryoung KW.	J Biol Chem	10.1016/j.jbc.2023.102917	2023
Genetics	Genomics and functional genomics with haloarchaea.	Soppa J, Baumann A, Brenneis M, Dambeck M, Hering O, Lange C.	Arch Microbiol	10.1007/s00203-008-0376-4	2008
Metabolism	The Archaeal Proteome Project advances knowledge about archaeal cell biology through comprehensive proteomics.	Schulze S, Adams Z, Cerletti M, De Castro R, Ferreira-Cerca S, Fufezan C, Gimenez MI, Hippler M, Jevtic Z, Knuppel R, Legerme G, Lenz C, Marchfelder A, Maupin-Furlow J, Paggi RA, Pfeiffer F, Poetsch A, Urlaub H, Pohlschroder M.	Nat Commun	10.1038/s41467-020-16784-7	2020
Enzymology	Salt-dependent studies of NADP-dependent isocitrate dehydrogenase from the halophilic archaeon Haloferax volcanii.	Madern D, Camacho M, Rodriguez-Arnedo A, Bonete MJ, Zaccai G.	Extremophiles	10.1007/s00792-004-0398-z	2004
Enzymology	In vivo characterization of the homing endonuclease within the polB gene in the halophilic archaeon Haloferax volcanii.	Naor A, Lazary R, Barzel A, Papke RT, Gophna U.	PLoS One	10.1371/journal.pone.0015833	2011
Metabolism	ArtA-Dependent Processing of a Tat Substrate Containing a Conserved Tripartite Structure That Is Not Localized at the C Terminus.	Abdul Halim MF, Stoltzfus JD, Schulze S, Hippler M, Pohlschroder M.	J Bacteriol	10.1128/jb.00802-16	2017
Metabolism	Dihydroxyacetone metabolism in Haloferax volcanii.	Ouellette M, Makkay AM, Papke RT.	Front Microbiol	10.3389/fmicb.2013.00376	2013
	Interplay of intracellular and trans-cellular DNA methylation in natural archaeal consortia.	Reva ON, La Cono V, Crisafi F, Smedile F, Mudaliyar M, Ghosal D, Giuliano L, Krupovic M, Yakimov MM.	Environ Microbiol Rep	10.1111/1758-2229.13258	2024
	tRNA-derived fragments target the ribosome and function as regulatory non-coding RNA in Haloferax volcanii.	Gebetsberger J, Zywicki M, Kunzi A, Polacek N.	Archaea	10.1155/2012/260909	2012
Metabolism	In the Archaea Haloferax volcanii, membrane protein biogenesis and protein synthesis rates are affected by decreased ribosomal binding to the translocon.	Ring G, Eichler J.	J Biol Chem	10.1074/jbc.m410590200	2004
Transcriptome	Genome-wide identification of transcriptional start sites in the haloarchaeon Haloferax volcanii based on differential RNA-Seq (dRNA-Seq).	Babski J, Haas KA, Nather-Schindler D, Pfeiffer F, Forstner KU, Hammelmann M, Hilker R, Becker A, Sharma CM, Marchfelder A, Soppa J.	BMC Genomics	10.1186/s12864-016-2920-y	2016
Metabolism	Characterization of the ATP-Dependent Lon-Like Protease in Methanobrevibacter smithii.	Pei J, Yan J, Jiang Y.	Archaea	10.1155/2016/5759765	2016
Genetics	The haloarchaeal MCM proteins: bioinformatic analysis and targeted mutagenesis of the beta7-beta8 and beta9-beta10 hairpin loops and conserved zinc binding domain cysteines.	Kristensen TP, Maria Cherian R, Gray FC, MacNeill SA.	Front Microbiol	10.3389/fmicb.2014.00123	2014
Enzymology	Structure-function relationships of archaeal Cbf5 during in vivo RNA-guided pseudouridylation.	Majumder M, Bosmeny MS, Gupta R.	RNA	10.1261/rna.057547.116	2016
Transcriptome	Sequencing of seven haloarchaeal genomes reveals patterns of genomic flux.	Lynch EA, Langille MG, Darling A, Wilbanks EG, Haltiner C, Shao KS, Starr MO, Teiling C, Harkins TT, Edwards RA, Eisen JA, Facciotti MT.	PLoS One	10.1371/journal.pone.0041389	2012
Metabolism	Stabilization of an archaeal DNA-sliding clamp protein, PCNA, by proteasome-activating nucleotidase gene knockout in Haloferax volcanii.	Kirkland PA, Maupin-Furlow JA.	FEMS Microbiol Lett	10.1111/j.1574-6968.2009.01547.x	2009
Metabolism	Membrane binding of ribosomes occurs at SecYE-based sites in the Archaea Haloferax volcanii.	Ring G, Eichler J.	J Mol Biol	10.1016/j.jmb.2004.01.008	2004
Metabolism	Sucrose Metabolism in Haloarchaea: Reassessment Using Genomics, Proteomics, and Metagenomics.	Williams TJ, Allen MA, Liao Y, Raftery MJ, Cavicchioli R.	Appl Environ Microbiol	10.1128/aem.02935-18	2019
	Non-canonical transcriptional start sites in E. coli O157:H7 EDL933 are regulated and appear in surprisingly high numbers.	Zehentner B, Scherer S, Neuhaus K.	BMC Microbiol	10.1186/s12866-023-02988-6	2023
	Generation of comprehensive transposon insertion mutant library for the model archaeon, Haloferax volcanii, and its use for gene discovery.	Kiljunen S, Pajunen MI, Dilks K, Storf S, Pohlschroder M, Savilahti H.	BMC Biol	10.1186/s12915-014-0103-3	2014
Metabolism	Membrane binding of SRP pathway components in the halophilic archaea Haloferax volcanii.	Lichi T, Ring G, Eichler J.	Eur J Biochem	10.1111/j.1432-1033.2004.04050.x	2004
	Revisiting microbial exopolysaccharides: a biocompatible and sustainable polymeric material for multifaceted biomedical applications.	Kiran NS, Yashaswini C, Singh S, Prajapati BG.	3 Biotech	10.1007/s13205-024-03946-3	2024
	Translational coupling via termination-reinitiation in archaea and bacteria.	Huber M, Faure G, Laass S, Kolbe E, Seitz K, Wehrheim C, Wolf YI, Koonin EV, Soppa J.	Nat Commun	10.1038/s41467-019-11999-9	2019
	Valorization of Waste from Argan Seeds for Polyhydroxybutyrate Production Using Bacterial Strains Isolated from Argan Soils.	Aragosa A, Specchia V, Frigione M.	Polymers (Basel)	10.3390/polym15081972	2023
	Genetic analysis of homologous recombination in Archaea: Haloferax volcanii as a model organism.	Allers T, Ngo HP.	Biochem Soc Trans	10.1042/bst0310706	2003
	tRNA-derived small RNAs: New players in genome protection against retrotransposons.	Martinez G.	RNA Biol	10.1080/15476286.2017.1403000	2018
Proteome	Uncovering the small proteome of Methanosarcina mazei using Ribo-seq and peptidomics under different nitrogen conditions.	Tufail MA, Jordan B, Hadjeras L, Gelhausen R, Cassidy L, Habenicht T, Gutt M, Hellwig L, Backofen R, Tholey A, Sharma CM, Schmitz RA.	Nat Commun	10.1038/s41467-024-53008-8	2024
Enzymology	The heterodimeric primase from the euryarchaeon Pyrococcus abyssi: a multifunctional enzyme for initiation and repair?	Le Breton M, Henneke G, Norais C, Flament D, Myllykallio H, Querellou J, Raffin JP.	J Mol Biol	10.1016/j.jmb.2007.10.015	2007
	The thiolation of uridine 34 in tRNA, which controls protein translation, depends on a [4Fe-4S] cluster in the archaeum Methanococcus maripaludis.	Bimai O, Legrand P, Ravanat JL, Touati N, Zhou J, He N, Lenon M, Barras F, Fontecave M, Golinelli-Pimpaneau B.	Sci Rep	10.1038/s41598-023-32423-9	2023
	Construction of Expression Shuttle Vectors for the Haloarchaeon Natrinema sp. J7 Based on Its Chromosomal Origins of Replication.	Wang Y, Chen B, Sima L, Cao M, Chen X.	Archaea	10.1155/2017/4237079	2017
	Identification, Characterization, and Application of the Replicon Region of the Halophilic Temperate Sphaerolipovirus SNJ1.	Wang Y, Sima L, Lv J, Huang S, Liu Y, Wang J, Krupovic M, Chen X.	J Bacteriol	10.1128/jb.00131-16	2016
	Biosynthesis of silver nanoparticles using Haloferax sp. NRS1: image analysis, characterization, in vitro thrombolysis and cytotoxicity.	Tag HM, Saddiq AA, Alkinani M, Hagagy N.	AMB Express	10.1186/s13568-021-01235-3	2021
	Liposome adjuvants prepared from the total polar lipids of Haloferax volcanii, Planococcus spp. and Bacillus firmus differ in ability to elicit and sustain immune responses.	Sprott GD, Dicaire CJ, Gurnani K, Deschatelets LA, Krishnan L.	Vaccine	10.1016/j.vaccine.2003.11.054	2004
Metabolism	AglS, a novel component of the Haloferax volcanii N-glycosylation pathway, is a dolichol phosphate-mannose mannosyltransferase.	Cohen-Rosenzweig C, Yurist-Doutsch S, Eichler J.	J Bacteriol	10.1128/jb.01716-12	2012
Metabolism	Interactions of RadB, a DNA repair protein in archaea, with DNA and ATP.	Guy CP, Haldenby S, Brindley A, Walsh DA, Briggs GS, Warren MJ, Allers T, Bolt EL.	J Mol Biol	10.1016/j.jmb.2006.02.010	2006
	Replication Origin Deletion Enhances Poly(3-Hydroxybutyrate-co-3-Hydroxyvalerate) Synthesis in Haloarchaea.	Yang H, Chen J, Mitra R, Xue Q, Xiang H, Han J.	Microbiol Spectr	10.1128/spectrum.02149-22	2022
Phylogeny	Lipids of the ultra-thin square halophilic archaeon Haloquadratum walsbyi.	Lobasso S, Lopalco P, Mascolo G, Corcelli A.	Archaea	10.1155/2008/870191	2008
	The role and mechanism of action of tRNA-derived fragments in the diagnosis and treatment of malignant tumors.	Gong M, Deng Y, Xiang Y, Ye D.	Cell Commun Signal	10.1186/s12964-023-01079-3	2023
Metabolism	AglR is required for addition of the final mannose residue of the N-linked glycan decorating the Haloferax volcanii S-layer glycoprotein.	Kaminski L, Guan Z, Abu-Qarn M, Konrad Z, Eichler J.	Biochim Biophys Acta	10.1016/j.bbagen.2012.06.014	2012
	In vitro Analysis of Ubiquitin-like Protein Modification in Archaea.	Fu X, Adams Z, Maupin-Furlow JA.	Bio Protoc	10.21769/bioprotoc.2845	2018
Enzymology	Isolation of fusion proteins containing SecY and SecE, components of the protein translocation complex from the halophilic archaeon Haloferax volcanii.	Irihimovitch V, Ring G, Elkayam T, Konrad Z, Eichler J.	Extremophiles	10.1007/s00792-002-0297-0	2003
Metabolism	Different routes to the same ending: comparing the N-glycosylation processes of Haloferax volcanii and Haloarcula marismortui, two halophilic archaea from the Dead Sea.	Calo D, Guan Z, Naparstek S, Eichler J.	Mol Microbiol	10.1111/j.1365-2958.2011.07781.x	2011
Genetics	Determining virus-host interactions and glycerol metabolism profiles in geographically diverse solar salterns with metagenomics.	Moller AG, Liang C.	PeerJ	10.7717/peerj.2844	2017
Metabolism	Protein glycosylation as an adaptive response in Archaea: growth at different salt concentrations leads to alterations in Haloferax volcanii S-layer glycoprotein N-glycosylation.	Guan Z, Naparstek S, Calo D, Eichler J.	Environ Microbiol	10.1111/j.1462-2920.2011.02625.x	2012
	Analysis of the external signals driving the transcriptional regulation of the main genes involved in denitrification in Haloferax mediterranei.	Miralles-Robledillo JM, Martinez-Espinosa RM, Pire C.	Front Microbiol	10.3389/fmicb.2023.1109550	2023
Metabolism	Expression in Haloferax volcanii of 3-hydroxy-3-methylglutaryl coenzyme A synthase facilitates isolation and characterization of the active form of a key enzyme required for polyisoprenoid cell membrane biosynthesis in halophilic archaea.	VanNice JC, Skaff DA, Wyckoff GJ, Miziorko HM.	J Bacteriol	10.1128/jb.00485-13	2013
Metabolism	Intracellular dynamics of archaeal FANCM homologue Hef in response to halted DNA replication.	Lestini R, Laptenok SP, Kuhn J, Hink MA, Schanne-Klein MC, Liebl U, Myllykallio H.	Nucleic Acids Res	10.1093/nar/gkt816	2013
Enzymology	Characterization of D-xylonate dehydratase YjhG from Escherichia coli.	Jiang Y, Liu W, Cheng T, Cao Y, Zhang R, Xian M.	Bioengineered	10.1080/21655979.2015.1040208	2015
Enzymology	Identification and characterization of gshA, a gene encoding the glutamate-cysteine ligase in the halophilic archaeon Haloferax volcanii.	Malki L, Yanku M, Borovok I, Cohen G, Mevarech M, Aharonowitz Y.	J Bacteriol	10.1128/jb.00297-09	2009
Metabolism	Properties of the chaperonin complex from the halophilic archaeon Haloferax volcanii.	Large AT, Kovacs E, Lund PA.	FEBS Lett	10.1016/s0014-5793(02)03685-2	2002
Genetics	A manual curation strategy to improve genome annotation: application to a set of haloarchael genomes.	Pfeiffer F, Oesterhelt D.	Life (Basel)	10.3390/life5021427	2015
	An alternative pathway for reduced folate biosynthesis in bacteria and halophilic archaea.	Levin I, Giladi M, Altman-Price N, Ortenberg R, Mevarech M.	Mol Microbiol	10.1111/j.1365-2958.2004.04339.x	2004
	How Important Is Protein Diffusion in Prokaryotes?	Schavemaker PE, Boersma AJ, Poolman B.	Front Mol Biosci	10.3389/fmolb.2018.00093	2018
Metabolism	DNA damage induces nucleoid compaction via the Mre11-Rad50 complex in the archaeon Haloferax volcanii.	Delmas S, Duggin IG, Allers T.	Mol Microbiol	10.1111/mmi.12091	2013
Metabolism	Haloferax volcanii cells lacking the flagellin FlgA2 are hypermotile.	Tripepi M, Esquivel RN, Wirth R, Pohlschroder M.	Microbiology (Reading)	10.1099/mic.0.069617-0	2013
	Crystal structure of the ubiquitin-like small archaeal modifier protein 2 from Haloferax volcanii.	Li Y, Maciejewski MW, Martin J, Jin K, Zhang Y, Maupin-Furlow JA, Hao B.	Protein Sci	10.1002/pro.2305	2013
	A Novel Noncoding RNA dsr11 Involved in Heat Stress Tolerance in Deinococcus radiodurans.	Xue D, Chen Y, Li J, Han J, Zhou Z, Zhang W, Chen M, Lin M, Ongena M, Wang J.	Biomolecules	10.3390/biom10010022	2019
	Halovirus HF2 Intergenic Repeat Sequences Carry Promoters.	Russ B, Pfeiffer F, Dyall-Smith M.	Viruses	10.3390/v13122388	2021
	StartLink and StartLink+: Prediction of Gene Starts in Prokaryotic Genomes.	Gemayel K, Lomsadze A, Borodovsky M.	Front Bioinform	10.3389/fbinf.2021.704157	2021
Enzymology	Molecular Cloning and Exploration of the Biochemical and Functional Analysis of Recombinant Glucose-6-Phosphate Dehydrogenase from Gluconoacetobacter diazotrophicus PAL5.	Ramirez-Nava EJ, Ortega-Cuellar D, Gonzalez-Valdez A, Castillo-Rodriguez RA, Ponce-Soto GY, Hernandez-Ochoa B, Cardenas-Rodriguez N, Martinez-Rosas V, Morales-Luna L, Serrano-Posada H, Sierra-Palacios E, Arreguin-Espinosa R, Cuevas-Cruz M, Rocha-Ramirez LM, Perez de la Cruz V, Marcial-Quino J, Gomez-Manzo S.	Int J Mol Sci	10.3390/ijms20215279	2019
	Novel polar lipids of halophilic eubacterium Planococcus H8 and archaeon Haloferax volcanii.	Sprott GD, Larocque S, Cadotte N, Dicaire CJ, McGee M, Brisson JR.	Biochim Biophys Acta	10.1016/j.bbalip.2003.08.001	2003
	Construction and usage of a onefold-coverage shotgun DNA microarray to characterize the metabolism of the archaeon Haloferax volcanii.	Zaigler A, Schuster SC, Soppa J.	Mol Microbiol	10.1046/j.1365-2958.2003.03497.x	2003
Metabolism	Fructose degradation in the haloarchaeon Haloferax volcanii involves a bacterial type phosphoenolpyruvate-dependent phosphotransferase system, fructose-1-phosphate kinase, and class II fructose-1,6-bisphosphate aldolase.	Pickl A, Johnsen U, Schonheit P.	J Bacteriol	10.1128/jb.00200-12	2012
Genetics	From replication to cultivation: hot news from Haloarchaea.	Soppa J.	Curr Opin Microbiol	10.1016/j.mib.2005.10.012	2005
	The lysogenic region of virus phiCh1: identification of a repressor-operator system and determination of its activity in halophilic Archaea.	Iro M, Klein R, Galos B, Baranyi U, Rossler N, Witte A.	Extremophiles	10.1007/s00792-006-0040-3	2007
Metabolism	Glyco-engineering in Archaea: differential N-glycosylation of the S-layer glycoprotein in a transformed Haloferax volcanii strain.	Calo D, Guan Z, Eichler J.	Microb Biotechnol	10.1111/j.1751-7915.2011.00250.x	2011
Phylogeny	Osmoregulation in freshwater anaerobic methane-oxidizing archaea under salt stress.	Echeveste Medrano MJ, Leu AO, Pabst M, Lin Y, McIlroy SJ, Tyson GW, van Ede J, Sanchez-Andrea I, Jetten MSM, Jansen R, Welte CU.	ISME J	10.1093/ismejo/wrae137	2024
Metabolism	Post-translational secretion of fusion proteins in the halophilic archaea Haloferax volcanii.	Irihimovitch V, Eichler J.	J Biol Chem	10.1074/jbc.m210762200	2003
	In vitro reconstitution and characterisation of the oxidative D-xylose pathway for production of organic acids and alcohols.	Boer H, Andberg M, Pylkkanen R, Maaheimo H, Koivula A.	AMB Express	10.1186/s13568-019-0768-7	2019
	Sialic Acid-Like Sugars in Archaea: Legionaminic Acid Biosynthesis in the Halophile Halorubrum sp. PV6.	Zaretsky M, Roine E, Eichler J.	Front Microbiol	10.3389/fmicb.2018.02133	2018
Genetics	The Exploration of Novel Regulatory Relationships Drives Haloarchaeal Operon-Like Structural Dynamics over Short Evolutionary Distances.	Seitzer P, Yao AI, Cisneros A, Facciotti MT.	Microorganisms	10.3390/microorganisms8121900	2020
Genetics	From genomes to function: haloarchaea as model organisms.	Soppa J.	Microbiology (Reading)	10.1099/mic.0.28504-0	2006
	Functional diversity of nanohaloarchaea within xylan-degrading consortia.	Reva O, Messina E, La Cono V, Crisafi F, Smedile F, La Spada G, Marturano L, Selivanova EA, Rohde M, Krupovic M, Yakimov MM.	Front Microbiol	10.3389/fmicb.2023.1182464	2023
	Genome-Wide Analysis of Sugar Transporters Identifies the gtsA Gene for Glucose Transportation in Pseudomonas stutzeri A1501.	Liu Y, Shang L, Zhan Y, Lin M, Liu Z, Yan Y.	Microorganisms	10.3390/microorganisms8040592	2020
Genetics	Probabilistic model based on circular statistics for quantifying coverage depth dynamics originating from DNA replication.	Suzuki S, Yamada T.	PeerJ	10.7717/peerj.8722	2020
Genetics	Association between the dynamics of multiple replication origins and the evolution of multireplicon genome architecture in haloarchaea.	Wu Z, Yang H, Liu J, Wang L, Xiang H.	Genome Biol Evol	10.1093/gbe/evu219	2014
	Novel Homologs of Isopentenyl Phosphate Kinase Reveal Class-Wide Substrate Flexibility.	Kumar V, Johnson BP, Dimas DA, Singh S.	ChemCatChem	10.1002/cctc.202100595	2021
	The Ribbon-Helix-Helix Domain Protein CdrS Regulates the Tubulin Homolog ftsZ2 To Control Cell Division in Archaea.	Darnell CL, Zheng J, Wilson S, Bertoli RM, Bisson-Filho AW, Garner EC, Schmid AK.	mBio	10.1128/mbio.01007-20	2020
Metabolism	Unusual Phosphoenolpyruvate (PEP) Synthetase-Like Protein Crucial to Enhancement of Polyhydroxyalkanoate Accumulation in Haloferax mediterranei Revealed by Dissection of PEP-Pyruvate Interconversion Mechanism.	Chen J, Mitra R, Zhang S, Zuo Z, Lin L, Zhao D, Xiang H, Han J.	Appl Environ Microbiol	10.1128/aem.00984-19	2019
	In silico discovery of the myxosortases that process MYXO-CTERM and three novel prokaryotic C-terminal protein-sorting signals that share invariant Cys residues.	Haft DH.	J Bacteriol	10.1128/jb.00173-23	2024
	Light-dependent expression of four cryptic archaeal circadian gene homologs.	Maniscalco M, Nannen J, Sodi V, Silver G, Lowrey PL, Bidle KA.	Front Microbiol	10.3389/fmicb.2014.00079	2014
	Differential expression of genes influenced by changing salinity using RNA arbitrarily primed PCR in the archaeal halophile Haloferax volcanii.	Bidle KA.	Extremophiles	10.1007/s00792-002-0289-0	2003
	Transcriptional and translational dynamics underlying heat shock response in the thermophilic crenarchaeon Sulfolobus acidocaldarius.	Baes R, Grunberger F, Pyr Dit Ruys S, Couturier M, De Keulenaer S, Skevin S, Van Nieuwerburgh F, Vertommen D, Grohmann D, Ferreira-Cerca S, Peeters E.	mBio	10.1128/mbio.03593-22	2023
Metabolism	Protein glycosylation in Haloferax volcanii: partial characterization of a 98-kDa glycoprotein.	Konrad Z, Eichler J.	FEMS Microbiol Lett	10.1111/j.1574-6968.2002.tb11131.x	2002
	The 492-bp RM07 DNA fragment from the halophilic Archaea confers promoter activity in all three domains of life.	Yang Y, Huang YP, Shen P.	Curr Microbiol	10.1007/s00284-003-4034-4	2003
Metabolism	aglgenes, A curated and searchable database of archaeal N-glycosylation pathway components.	Godin N, Eichler J.	Database (Oxford)	10.1093/database/bau046	2014
Genetics	Exploiting the Type I-B CRISPR Genome Editing System in Thermoanaerobacterium aotearoense SCUT27 and Engineering the Strain for Enhanced Ethanol Production.	Dai K, Fu H, Guo X, Qu C, Lan Y, Wang J.	Appl Environ Microbiol	10.1128/aem.00751-22	2022
	Brucella abortus Encodes an Active Rhomboid Protease: Proteome Response after Rhomboid Gene Deletion.	Marchesini MI, Poetsch A, Guidolin LS, Comerci DJ.	Microorganisms	10.3390/microorganisms10010114	2022
	Essential requirements for the detection and degradation of invaders by the Haloferax volcanii CRISPR/Cas system I-B.	Maier LK, Lange SJ, Stoll B, Haas KA, Fischer S, Fischer E, Duchardt-Ferner E, Wohnert J, Backofen R, Marchfelder A.	RNA Biol	10.4161/rna.24282	2013
	Performance assessment of DNA sequencing platforms in the ABRF Next-Generation Sequencing Study.	Foox J, Tighe SW, Nicolet CM, Zook JM, Byrska-Bishop M, Clarke WE, Khayat MM, Mahmoud M, Laaguiby PK, Herbert ZT, Warner D, Grills GS, Jen J, Levy S, Xiang J, Alonso A, Zhao X, Zhang W, Teng F, Zhao Y, Lu H, Schroth GP, Narzisi G, Farmerie W, Sedlazeck FJ, Baldwin DA, Mason CE.	Nat Biotechnol	10.1038/s41587-021-01049-5	2021
Enzymology	Double mutations far from the active site affect cold activity in an Antarctic halophilic beta-galactosidase.	Laye VJ, DasSarma S.	Protein Sci	10.1002/pro.4264	2022
Metabolism	The presence of the ACA box in archaeal H/ACA guide RNAs promotes atypical pseudouridylation.	Majumder M, Mukhopadhyay S, Kharel P, Gupta R.	RNA	10.1261/rna.073734.119	2020
	A Modular Vector Toolkit with a Tailored Set of Thermosensors To Regulate Gene Expression in Thermus thermophilus.	Verdu C, Sanchez E, Ortega C, Hidalgo A, Berenguer J, Mencia M, Mencia M.	ACS Omega	10.1021/acsomega.9b02107	2019
	Electron cryo-microscopy reveals the structure of the archaeal thread filament.	Gaines MC, Isupov MN, Sivabalasarma S, Haque RU, McLaren M, Mollat CL, Tripp P, Neuhaus A, Gold VAM, Albers SV, Daum B.	Nat Commun	10.1038/s41467-022-34652-4	2022
	High throughput sequencing reveals a plethora of small RNAs including tRNA derived fragments in Haloferax volcanii.	Heyer R, Dorr M, Jellen-Ritter A, Spath B, Babski J, Jaschinski K, Soppa J, Marchfelder A.	RNA Biol	10.4161/rna.20826	2012
Metabolism	tRNA 3' end maturation in archaea has eukaryotic features: the RNase Z from Haloferax volcanii.	Schierling K, Rosch S, Rupprecht R, Schiffer S, Marchfelder A.	J Mol Biol	10.1006/jmbi.2001.5395	2002
Metabolism	Modeling leaderless transcription and atypical genes results in more accurate gene prediction in prokaryotes.	Lomsadze A, Gemayel K, Tang S, Borodovsky M.	Genome Res	10.1101/gr.230615.117	2018
Metabolism	Assigning a function to a conserved archaeal metallo-beta-lactamase from Haloferax volcanii.	Fischer S, John von Freyend S, Sabag-Daigle A, Daniels CJ, Allers T, Marchfelder A.	Extremophiles	10.1007/s00792-012-0433-4	2012
Metabolism	Assessment of Haloferax mediterranei Genome in Search of Copper-Molecular Machinery With Potential Applications for Bioremediation.	Llorca MG, Martinez-Espinosa RM.	Front Microbiol	10.3389/fmicb.2022.895296	2022
	Characterization of a small tRNA-binding protein that interacts with the archaeal proteasome complex.	Hogrel G, Marino-Puertas L, Laurent S, Ibrahim Z, Coves J, Girard E, Gabel F, Fenel D, Daugeron MC, Clouet-d'Orval B, Basta T, Flament D, Franzetti B.	Mol Microbiol	10.1111/mmi.14948	2022
	Conserved substitution patterns around nucleosome footprints in eukaryotes and Archaea derive from frequent nucleosome repositioning through evolution.	Warnecke T, Becker EA, Facciotti MT, Nislow C, Lehner B.	PLoS Comput Biol	10.1371/journal.pcbi.1003373	2013
Metabolism	GvpD-induced breakdown of the transcriptional activator GvpE of halophilic archaea requires a functional p-loop and an arginine-rich region of GvpD.	Scheuch S, Pfeifer F.	Microbiology (Reading)	10.1099/mic.0.2006/004499-0	2007
Genetics	Phenotypic Characterization of Sulfolobus islandicus Strains Lacking the B-Family DNA Polymerases PolB2 and PolB3 Individually and in Combination.	Bohall PB, Bell SD.	Front Microbiol	10.3389/fmicb.2021.666974	2021
	Arabidopsis tRNA-derived fragments as potential modulators of translation.	Lalande S, Merret R, Salinas-Giege T, Drouard L.	RNA Biol	10.1080/15476286.2020.1722514	2020
Metabolism	Identification of residues important for the activity of Haloferax volcanii AglD, a component of the archaeal N-glycosylation pathway.	Kaminski L, Eichler J.	Archaea	10.1155/2010/315108	2010
Genetics	Escherichia coli cell factories with altered chromosomal replication scenarios exhibit accelerated growth and rapid biomass production.	Yang HJ, Kim K, Kwon SK, Kim JF.	Microb Cell Fact	10.1186/s12934-022-01851-z	2022
	Haloferax volcanii, a prokaryotic species that does not use the Shine Dalgarno mechanism for translation initiation at 5'-UTRs.	Kramer P, Gabel K, Pfeiffer F, Soppa J.	PLoS One	10.1371/journal.pone.0094979	2014
Metabolism	Sequential 2'-O-methylation of archaeal pre-tRNATrp nucleotides is guided by the intron-encoded but trans-acting box C/D ribonucleoprotein of pre-tRNA.	Singh SK, Gurha P, Tran EJ, Maxwell ES, Gupta R.	J Biol Chem	10.1074/jbc.m408868200	2004
Metabolism	Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.	Serrano JA, Bonete MJ.	Biochim Biophys Acta	10.1016/s0167-4781(01)00263-9	2001
	NADP-dependent isocitrate dehydrogenase from the halophilic archaeon Haloferax volcanii: cloning, sequence determination and overexpression in Escherichia coli.	Camacho M, Rodriguez-Arnedo A, Bonete MJ.	FEMS Microbiol Lett	10.1111/j.1574-6968.2002.tb11125.x	2002
Metabolism	Characterization of inverted membrane vesicles from the halophilic archaeon Haloferax volcanii.	Ring G, Eichler J.	J Membr Biol	10.1007/s00232-001-0067-4	2001
Metabolism	DNA as a phosphate storage polymer and the alternative advantages of polyploidy for growth or survival.	Zerulla K, Chimileski S, Nather D, Gophna U, Papke RT, Soppa J.	PLoS One	10.1371/journal.pone.0094819	2014
Metabolism	AglJ adds the first sugar of the N-linked pentasaccharide decorating the Haloferax volcanii S-layer glycoprotein.	Kaminski L, Abu-Qarn M, Guan Z, Naparstek S, Ventura VV, Raetz CR, Hitchen PG, Dell A, Eichler J.	J Bacteriol	10.1128/jb.00705-10	2010
Enzymology	The effect of salts on the activity and stability of Escherichia coli and Haloferax volcanii dihydrofolate reductases.	Wright DB, Banks DD, Lohman JR, Hilsenbeck JL, Gloss LM.	J Mol Biol	10.1016/s0022-2836(02)00916-6	2002
Metabolism	Urm1: A Non-Canonical UBL.	Termathe M, Leidel SA.	Biomolecules	10.3390/biom11020139	2021
Metabolism	The DNA-binding protein HTa from Thermoplasma acidophilum is an archaeal histone analog.	Hocher A, Rojec M, Swadling JB, Esin A, Warnecke T.	Elife	10.7554/elife.52542	2019
Enzymology	Insights into the evolutionary conserved regulation of Rio ATPase activity.	Knuppel R, Christensen RH, Gray FC, Esser D, Strauss D, Medenbach J, Siebers B, MacNeill SA, LaRonde N, Ferreira-Cerca S.	Nucleic Acids Res	10.1093/nar/gkx1236	2018
	Revisiting evolutionary trajectories and the organization of the Pleolipoviridae family.	Alarcon-Schumacher T, Lucking D, Erdmann S.	PLoS Genet	10.1371/journal.pgen.1010998	2023
	Internal Promoters and Their Effects on the Transcription of Operon Genes for Epothilone Production in Myxococcus xanthus.	Wang Y, Yue XJ, Yuan SF, Hong Y, Hu WF, Li YZ.	Front Bioeng Biotechnol	10.3389/fbioe.2021.758561	2021
Enzymology	Towards glycoengineering in archaea: replacement of Haloferax volcanii AglD with homologous glycosyltransferases from other halophilic archaea.	Calo D, Eilam Y, Lichtenstein RG, Eichler J.	Appl Environ Microbiol	10.1128/aem.00681-10	2010
	Towards a systems approach in the genetic analysis of archaea: Accelerating mutant construction and phenotypic analysis in Haloferax volcanii.	Blaby IK, Phillips G, Blaby-Haas CE, Gulig KS, El Yacoubi B, de Crecy-Lagard V.	Archaea	10.1155/2010/426239	2010
	Nucleotides Flanking the Start Codon in hsp70 mRNAs with Very Short 5'-UTRs Greatly Affect Gene Expression in Haloarchaea.	Chen W, Yang G, He Y, Zhang S, Chen H, Shen P, Chen X, Huang YP.	PLoS One	10.1371/journal.pone.0138473	2015
Metabolism	Archaea signal recognition particle shows the way.	Zwieb C, Bhuiyan S.	Archaea	10.1155/2010/485051	2010
	DNA binding in high salt: analysing the salt dependence of replication protein A3 from the halophile Haloferax volcanii.	Winter JA, Patoli B, Bunting KA.	Archaea	10.1155/2012/719092	2012
Metabolism	Haloarchaea Endowed with Phosphorus Solubilization Attribute Implicated in Phosphorus Cycle.	Yadav AN, Sharma D, Gulati S, Singh S, Dey R, Pal KK, Kaushik R, Saxena AK.	Sci Rep	10.1038/srep12293	2015
Genetics	Folding Features and Dynamics of 3D Genome Architecture in Plant Fungal Pathogens.	Xia C, Huang L, Huang J, Zhang H, Huang Y, Benhamed M, Wang M, Chen X, Zhang M, Liu T, Chen W.	Microbiol Spectr	10.1128/spectrum.02608-22	2022
	Conversion of Mevalonate 3-Kinase into 5-Phosphomevalonate 3-Kinase by Single Amino Acid Mutations.	Motoyama K, Sobue F, Kawaide H, Yoshimura T, Hemmi H.	Appl Environ Microbiol	10.1128/aem.00256-19	2019
	Non-Coding RNAs are Differentially Expressed by Nocardia brasiliensis in Vitro and in Experimental Actinomycetoma.	Cruz-Rabadan JS, Miranda-Rios J, Espin-Ocampo G, Mendez-Tovar LJ, Maya-Pineda HR, Hernandez-Hernandez F.	Open Microbiol J	10.2174/1874285801711010112	2017
	Bacterial origins of thymidylate metabolism in Asgard archaea and Eukarya.	Filee J, Becker HF, Mellottee L, Eddine RZ, Li Z, Yin W, Lambry JC, Liebl U, Myllykallio H.	Nat Commun	10.1038/s41467-023-36487-z	2023
Metabolism	Activity-based protein profiling as a robust method for enzyme identification and screening in extremophilic Archaea.	Zweerink S, Kallnik V, Ninck S, Nickel S, Verheyen J, Blum M, Wagner A, Feldmann I, Sickmann A, Albers SV, Brasen C, Kaschani F, Siebers B, Kaiser M.	Nat Commun	10.1038/ncomms15352	2017
	Probing the sORF-Encoded Peptides of Deinococcus radiodurans in Response to Extreme Stress.	Zhou C, Wang Q, Huang Y, Chen Z, Chen S, Zhao Y, Jia C.	Mol Cell Proteomics	10.1016/j.mcpro.2022.100423	2022
Metabolism	Effect of amino acid starvation on glucose transport in two archaeal organisms.	Scoarughi GL, Santino I, Sessa R, Cimmino C, Donini P.	FEMS Microbiol Lett	10.1111/j.1574-6968.2003.tb11496.x	2003
	A new simvastatin (mevinolin)-resistance marker from Haloarcula hispanica and a new Haloferax volcanii strain cured of plasmid pHV2.	Wendoloski D, Ferrer C, Dyall-Smith ML.	Microbiology (Reading)	10.1099/00221287-147-4-959	2001
	Culexarchaeia, a novel archaeal class of anaerobic generalists inhabiting geothermal environments.	Kohtz AJ, Jay ZJ, Lynes MM, Krukenberg V, Hatzenpichler R.	ISME Commun	10.1038/s43705-022-00175-8	2022
Metabolism	Internal RNAs overlapping coding sequences can drive the production of alternative proteins in archaea.	Ten-Caten F, Vencio RZN, Lorenzetti APR, Zaramela LS, Santana AC, Koide T.	RNA Biol	10.1080/15476286.2018.1509661	2018
Genetics	Phyletic Distribution and Diversification of the Phage Shock Protein Stress Response System in Bacteria and Archaea.	Popp PF, Gumerov VM, Andrianova EP, Bewersdorf L, Mascher T, Zhulin IB, Wolf D.	mSystems	10.1128/msystems.01348-21	2022
	Accelerated growth in the absence of DNA replication origins.	Hawkins M, Malla S, Blythe MJ, Nieduszynski CA, Allers T.	Nature	10.1038/nature12650	2013
	A comprehensive analysis of the importance of translation initiation factors for Haloferax volcanii applying deletion and conditional depletion mutants.	Gabel K, Schmitt J, Schulz S, Nather DJ, Soppa J.	PLoS One	10.1371/journal.pone.0077188	2013
	Revisiting the structure/function relationships of H/ACA(-like) RNAs: a unified model for Euryarchaea and Crenarchaea.	Toffano-Nioche C, Gautheret D, Leclerc F.	Nucleic Acids Res	10.1093/nar/gkv756	2015
Genetics	The Hyperthermophilic Restriction-Modification Systems of Thermococcus kodakarensis Protect Genome Integrity.	Zatopek KM, Burkhart BW, Morgan RD, Gehring AM, Scott KA, Santangelo TJ, Gardner AF.	Front Microbiol	10.3389/fmicb.2021.657356	2021
	Post-translational modification of the S-layer glycoprotein occurs following translocation across the plasma membrane of the haloarchaeon Haloferax volcanii.	Eichler J.	Eur J Biochem	10.1046/j.1432-1327.2001.02361.x	2001
Metabolism	Box C/D RNA-guided 2'-O methylations and the intron of tRNATrp are not essential for the viability of Haloferax volcanii.	Joardar A, Gurha P, Skariah G, Gupta R.	J Bacteriol	10.1128/jb.00820-08	2008
	A paralog of Pcc1 is the fifth core subunit of the KEOPS tRNA-modifying complex in Archaea.	Daugeron MC, Missoury S, Da Cunha V, Lazar N, Collinet B, van Tilbeurgh H, Basta T.	Nat Commun	10.1038/s41467-023-36210-y	2023
	Archaeal Tuc1/Ncs6 homolog required for wobble uridine tRNA thiolation is associated with ubiquitin-proteasome, translation, and RNA processing system homologs.	Chavarria NE, Hwang S, Cao S, Fu X, Holman M, Elbanna D, Rodriguez S, Arrington D, Englert M, Uthandi S, Soll D, Maupin-Furlow JA.	PLoS One	10.1371/journal.pone.0099104	2014
Enzymology	The extremely halophilic archaeon Haloferax volcanii has two very different dihydrofolate reductases.	Ortenberg R, Rozenblatt-Rosen O, Mevarech M.	Mol Microbiol	10.1046/j.1365-2958.2000.01815.x	2000
	Novel glycoproteins of the halophilic archaeon Haloferax volcanii.	Eichler J.	Arch Microbiol	10.1007/s002030000152	2000
Enzymology	Structure in an extreme environment: NMR at high salt.	Binbuga B, Boroujerdi AF, Young JK.	Protein Sci	10.1110/ps.072950407	2007
	Genetic and Functional Analyses of Archaeal ATP-Dependent RNA Ligase in C/D Box sRNA Circularization and Ribosomal RNA Processing.	Liu Y, Takagi Y, Sugijanto M, Nguyen KDM, Hirata A, Hori H, Ho CK.	Front Mol Biosci	10.3389/fmolb.2022.811548	2022
	Genetic and Biochemical Identification of a Novel Single-Stranded DNA-Binding Complex in Haloferax volcanii.	Stroud A, Liddell S, Allers T.	Front Microbiol	10.3389/fmicb.2012.00224	2012
	2'-O-methylation of the wobble residue of elongator pre-tRNA(Met) in Haloferax volcanii is guided by a box C/D RNA containing unique features.	Joardar A, Malliahgari SR, Skariah G, Gupta R.	RNA Biol	10.4161/rna.8.5.16015	2011
	Genome-wide primary transcriptome analysis of H₂-producing archaeon Thermococcus onnurineus NA1.	Cho S, Kim MS, Jeong Y, Lee BR, Lee JH, Kang SG, Cho BK.	Sci Rep	10.1038/srep43044	2017
	Interplay between Position-Dependent Codon Usage Bias and Hydrogen Bonding at the 5' End of ORFeomes.	Villada JC, Duran MF, Lee PKH.	mSystems	10.1128/msystems.00613-20	2020
	Improved strains and plasmid vectors for conditional overexpression of His-tagged proteins in Haloferax volcanii.	Allers T, Barak S, Liddell S, Wardell K, Mevarech M.	Appl Environ Microbiol	10.1128/aem.02670-09	2010
Metabolism	Insights into synthesis and function of KsgA/Dim1-dependent rRNA modifications in archaea.	Knuppel R, Trahan C, Kern M, Wagner A, Grunberger F, Hausner W, Quax TEF, Albers SV, Oeffinger M, Ferreira-Cerca S.	Nucleic Acids Res	10.1093/nar/gkaa1268	2021
Enzymology	Characterization of acetohydroxy acid synthase activity in the archaeon Haloferax volcanii.	Vyazmensky M, Barak Z, Chipman DM, Eichler J.	Comp Biochem Physiol B Biochem Mol Biol	10.1016/s0305-0491(99)00170-4	2000
	The archaeal KEOPS complex possesses a functional Gon7 homolog and has an essential function independent of the cellular t⁶A modification level.	Wu P, Gan Q, Zhang X, Yang Y, Xiao Y, She Q, Ni J, Huang Q, Shen Y.	mLife	10.1002/mlf2.12051	2023
Metabolism	A rhomboid protease gene deletion affects a novel oligosaccharide N-linked to the S-layer glycoprotein of Haloferax volcanii.	Parente J, Casabuono A, Ferrari MC, Paggi RA, De Castro RE, Couto AS, Gimenez MI.	J Biol Chem	10.1074/jbc.m113.546531	2014
Metabolism	A Novel Transcriptional Regulator Related to Thiamine Phosphate Synthase Controls Thiamine Metabolism Genes in Archaea.	Rodionov DA, Leyn SA, Li X, Rodionova IA.	J Bacteriol	10.1128/jb.00743-16	2017
Metabolism	The Oligosaccharyltransferase AglB Supports Surface-Associated Growth and Iron Oxidation in Methanococcus maripaludis.	Holten MP, Fonseca DR, Costa KC.	Appl Environ Microbiol	10.1128/aem.00995-21	2021
Metabolism	A Gateway platform for functional genomics in Haloferax volcanii: deletion of three tRNA modification genes.	El Yacoubi B, Phillips G, Blaby IK, Haas CE, Cruz Y, Greenberg J, de Crecy-Lagard V.	Archaea	10.1155/2009/428489	2009
	Nutrient supplementation experiments with saltern microbial communities implicate utilization of DNA as a source of phosphorus.	Hua Z, Ouellette M, Makkay AM, Papke RT, Zhaxybayeva O.	ISME J	10.1038/s41396-021-00960-8	2021
Metabolism	Hydrophobic carboxy-terminal residues dramatically reduce protein levels in the haloarchaeon Haloferax volcanii.	Reuter CJ, Uthandi S, Puentes JA, Maupin-Furlow JA.	Microbiology (Reading)	10.1099/mic.0.032995-0	2010
Metabolism	Translation initiation with GUC codon in the archaeon Halobacterium salinarum: implications for translation of leaderless mRNA and strict correlation between translation initiation and presence of mRNA.	Srinivasan G, Krebs MP, RajBhandary UL.	Mol Microbiol	10.1111/j.1365-2958.2005.04992.x	2006
Metabolism	A complex of Cas proteins 5, 6, and 7 is required for the biogenesis and stability of clustered regularly interspaced short palindromic repeats (crispr)-derived rnas (crrnas) in Haloferax volcanii.	Brendel J, Stoll B, Lange SJ, Sharma K, Lenz C, Stachler AE, Maier LK, Richter H, Nickel L, Schmitz RA, Randau L, Allers T, Urlaub H, Backofen R, Marchfelder A.	J Biol Chem	10.1074/jbc.m113.508184	2014
	A bZIP protein from halophilic archaea: structural features and dimer formation of cGvpE from Halobacterium salinarum.	Plosser P, Pfeifer F.	Mol Microbiol	10.1046/j.1365-2958.2002.03031.x	2002
Metabolism	Evidence for post-translational membrane insertion of the integral membrane protein bacterioopsin expressed in the heterologous halophilic archaeon Haloferax volcanii.	Ortenberg R, Mevarech M.	J Biol Chem	10.1074/jbc.m908916199	2000
	Novel archaeal adhesion pilins with a conserved N terminus.	Esquivel RN, Xu R, Pohlschroder M.	J Bacteriol	10.1128/jb.00572-13	2013
Phylogeny	Identities and phylogenetic comparisons of posttranscriptional modifications in 16 S ribosomal RNA from Haloferax volcanii.	Kowalak JA, Bruenger E, Crain PF, McCloskey JA.	J Biol Chem	10.1074/jbc.m002153200	2000
Metabolism	Species Widely Distributed in Halophilic Archaea Exhibit Opsin-Mediated Inhibition of Bacterioruberin Biosynthesis.	Peck RF, Graham SM, Gregory AM.	J Bacteriol	10.1128/jb.00576-18	2019
	Structural insights into the adaptation of proliferating cell nuclear antigen (PCNA) from Haloferax volcanii to a high-salt environment.	Morgunova E, Gray FC, Macneill SA, Ladenstein R.	Acta Crystallogr D Biol Crystallogr	10.1107/s0907444909029321	2009
Metabolism	Role for DNA double strand end-resection activity of RecBCD in control of aberrant chromosomal replication initiation in Escherichia coli.	Goswami S, Gowrishankar J.	Nucleic Acids Res	10.1093/nar/gkac670	2022
	Widespread CRISPR-derived RNA regulatory elements in CRISPR-Cas systems.	Shmakov SA, Barth ZK, Makarova KS, Wolf YI, Brover V, Peters JE, Koonin EV.	Nucleic Acids Res	10.1093/nar/gkad495	2023
Metabolism	Reversal of Regioselectivity in Zinc-Dependent Medium-Chain Alcohol Dehydrogenase from Rhodococcus erythropolis toward Octanone Derivatives.	Dhoke GV, Ensari Y, Hacibaloglu DY, Gartner A, Ruff AJ, Bocola M, Davari MD.	Chembiochem	10.1002/cbic.202000247	2020
Enzymology	Complementation of an aglB Mutant of Methanococcus maripaludis with Heterologous Oligosaccharyltransferases.	Ding Y, Vrionis HA, Schneider J, Berezuk A, Khursigara CM, Jarrell KF.	PLoS One	10.1371/journal.pone.0167611	2016
Metabolism	Expression of acetylcholine (ACh) and ACh-synthesizing activity in Archaea.	Yamada T, Fujii T, Kanai T, Amo T, Imanaka T, Nishimasu H, Wakagi T, Shoun H, Kamekura M, Kamagata Y, Kato T, Kawashima K.	Life Sci	10.1016/j.lfs.2005.01.026	2005
	Hundreds of novel composite genes and chimeric genes with bacterial origins contributed to haloarchaeal evolution.	Meheust R, Watson AK, Lapointe FJ, Papke RT, Lopez P, Bapteste E.	Genome Biol	10.1186/s13059-018-1454-9	2018
Enzymology	Halophilic enzyme activation induced by salts.	Ortega G, Lain A, Tadeo X, Lopez-Mendez B, Castano D, Millet O.	Sci Rep	10.1038/srep00006	2011
	Rhizosphere-dwelling halophilic archaea: a potential candidate for alleviating salinity-associated stress in agriculture.	Naitam MG, Ramakrishnan B, Grover M, Kaushik R.	Front Microbiol	10.3389/fmicb.2023.1212349	2023
Metabolism	The core and unique proteins of haloarchaea.	Capes MD, DasSarma P, DasSarma S.	BMC Genomics	10.1186/1471-2164-13-39	2012
Enzymology	Genetic evidence for the importance of protein acetylation and protein deacetylation in the halophilic archaeon Haloferax volcanii.	Altman-Price N, Mevarech M.	J Bacteriol	10.1128/jb.01252-08	2009
Metabolism	Phosphorylation and methylation of proteasomal proteins of the haloarcheon Haloferax volcanii.	Humbard MA, Reuter CJ, Zuobi-Hasona K, Zhou G, Maupin-Furlow JA.	Archaea	10.1155/2010/481725	2010
	Characterization of the Methanomicrobial Archaeal RNase Zs for Processing the CCA-Containing tRNA Precursors.	Wang X, Gu X, Li J, Yue L, Li D, Dong X.	Front Microbiol	10.3389/fmicb.2020.01851	2020
	Emerging views of genome organization in Archaea.	Takemata N, Bell SD.	J Cell Sci	10.1242/jcs.243782	2020
Metabolism	Identification of the polyhydroxyalkanoate (PHA)-specific acetoacetyl coenzyme A reductase among multiple FabG paralogs in Haloarcula hispanica and reconstruction of the PHA biosynthetic pathway in Haloferax volcanii.	Han J, Lu Q, Zhou L, Liu H, Xiang H.	Appl Environ Microbiol	10.1128/aem.00938-09	2009
	The cell surface glycoprotein layer of the extreme halophile Halobacterium salinarum and its relation to Haloferax volcanii: cryo-electron tomography of freeze-substituted cells and projection studies of negatively stained envelopes.	Trachtenberg S, Pinnick B, Kessel M.	J Struct Biol	10.1006/jsbi.2000.4215	2000
	The MetaCyc database of metabolic pathways and enzymes - a 2019 update.	Caspi R, Billington R, Keseler IM, Kothari A, Krummenacker M, Midford PE, Ong WK, Paley S, Subhraveti P, Karp PD.	Nucleic Acids Res	10.1093/nar/gkz862	2020
	The immune system of halophilic archaea.	Maier LK, Fischer S, Stoll B, Brendel J, Pfeiffer F, Dyall-Smith M, Marchfelder A.	Mob Genet Elements	10.4161/mge.22530	2012
	Distinct microbial community along the chronic oil pollution continuum of the Persian Gulf converge with oil spill accidents.	Rezaei Somee M, Dastgheib SMM, Shavandi M, Ghanbari Maman L, Kavousi K, Amoozegar MA, Mehrshad M.	Sci Rep	10.1038/s41598-021-90735-0	2021
Metabolism	In vivo analyses of constitutive and regulated promoters in halophilic archaea.	Gregor D, Pfeifer F.	Microbiology (Reading)	10.1099/mic.0.27541-0	2005
	Interaction of Haloarchaeal Gas Vesicle Proteins Determined by Split-GFP.	Winter K, Born J, Pfeifer F.	Front Microbiol	10.3389/fmicb.2018.01897	2018
	Comparative Analysis of Surface Layer Glycoproteins and Genes Involved in Protein Glycosylation in the Genus Haloferax.	Shalev Y, Soucy SM, Papke RT, Gogarten JP, Eichler J, Gophna U.	Genes (Basel)	10.3390/genes9030172	2018
Enzymology	Enhanced archaeal laccase production in recombinant Escherichia coli by modification of N-terminal propeptide and twin arginine translocation motifs.	Uthandi S, Prunetti L, De Vera IM, Fanucci GE, Angerhofer A, Maupin-Furlow JA.	J Ind Microbiol Biotechnol	10.1007/s10295-012-1152-7	2012
	Expression and heat-responsive regulation of a TFIIB homologue from the archaeon Haloferax volcanii.	Thompson DK, Palmer JR, Daniels CJ.	Mol Microbiol	10.1046/j.1365-2958.1999.01551.x	1999
	tRNA-derived short RNAs bind to Saccharomyces cerevisiae ribosomes in a stress-dependent manner and inhibit protein synthesis in vitro.	Bakowska-Zywicka K, Kasprzyk M, Twardowski T.	FEMS Yeast Res	10.1093/femsyr/fow077	2016
Enzymology	Expression, reactivation, and purification of enzymes from Haloferax volcanii in Escherichia coli.	Connaris H, Chaudhuri JB, Danson MJ, Hough DW.	Biotechnol Bioeng	10.1002/(sici)1097-0290(19990705)64:1<38::aid-bit4>3.0.co;2-7	1999
Metabolism	Unique recognition style of tRNA(Leu) by Haloferax volcanii leucyl-tRNA synthetase.	Soma A, Uchiyama K, Sakamoto T, Maeda M, Himeno H.	J Mol Biol	10.1006/jmbi.1999.3219	1999
Metabolism	Extensive proteolysis inhibits high-level production of eukaryal G protein-coupled receptors in the archaeon Haloferax volcanii.	Patenge N, Soppa J.	FEMS Microbiol Lett	10.1111/j.1574-6968.1999.tb13408.x	1999
Metabolism	Operation of glyoxylate cycle in halophilic archaea: presence of malate synthase and isocitrate lyase in Haloferax volcanii.	Serrano JA, Camacho M, Bonete MJ.	FEBS Lett	10.1016/s0014-5793(98)00911-9	1998
	Mechanical and structural properties of archaeal hypernucleosomes.	Henneman B, Brouwer TB, Erkelens AM, Kuijntjes GJ, van Emmerik C, van der Valk RA, Timmer M, Kirolos NCS, van Ingen H, van Noort J, Dame RT.	Nucleic Acids Res	10.1093/nar/gkaa1196	2021
Metabolism	E1- and ubiquitin-like proteins provide a direct link between protein conjugation and sulfur transfer in archaea.	Miranda HV, Nembhard N, Su D, Hepowit N, Krause DJ, Pritz JR, Phillips C, Soll D, Maupin-Furlow JA.	Proc Natl Acad Sci U S A	10.1073/pnas.1018151108	2011
Metabolism	Distinct glycan-charged phosphodolichol carriers are required for the assembly of the pentasaccharide N-linked to the Haloferax volcanii S-layer glycoprotein.	Guan Z, Naparstek S, Kaminski L, Konrad Z, Eichler J.	Mol Microbiol	10.1111/j.1365-2958.2010.07405.x	2010
	Heterologous expression in the Archaea: transcription from Pyrococcus furiosus gdh and mlrA promoters in Haloferax volcanii.	Schreier HJ, Robinson-Bidle KA, Romashko AM, Patel GV.	Extremophiles	10.1007/s007920050094	1999
Metabolism	Ubiquitin-Like Protein SAMP1 and JAMM/MPN+ Metalloprotease HvJAMM1 Constitute a System for Reversible Regulation of Metabolic Enzyme Activity in Archaea.	Cao S, Hepowit N, Maupin-Furlow JA.	PLoS One	10.1371/journal.pone.0128399	2015
	Exopolysaccharide composition and size in Sulfolobus acidocaldarius biofilms.	Kuschmierz L, Meyer M, Brasen C, Wingender J, Schmitz OJ, Siebers B.	Front Microbiol	10.3389/fmicb.2022.982745	2022
Genetics	The Genome Copy Number of the Thermophilic Cyanobacterium Thermosynechococcus elongatus E542 Is Controlled by Growth Phase and Nutrient Availability.	Riaz S, Xiao M, Chen P, Li M, Cui Y, Daroch M.	Appl Environ Microbiol	10.1128/aem.02993-20	2021
	In situ imaging of bacterial outer membrane projections and associated protein complexes using electron cryo-tomography.	Kaplan M, Chreifi G, Metskas LA, Liedtke J, Wood CR, Oikonomou CM, Nicolas WJ, Subramanian P, Zacharoff LA, Wang Y, Chang YW, Beeby M, Dobro MJ, Zhu Y, McBride MJ, Briegel A, Shaffer CL, Jensen GJ.	Elife	10.7554/elife.73099	2021
Metabolism	Archaeal ubiquitin-like proteins: functional versatility and putative ancestral involvement in tRNA modification revealed by comparative genomic analysis.	Makarova KS, Koonin EV.	Archaea	10.1155/2010/710303	2010
Metabolism	GlpR represses fructose and glucose metabolic enzymes at the level of transcription in the haloarchaeon Haloferax volcanii.	Rawls KS, Yacovone SK, Maupin-Furlow JA.	J Bacteriol	10.1128/jb.00827-10	2010
	Diversity of Lysis-Resistant Bacteria and Archaea in the Polyextreme Environment of Salar de Huasco.	Corona Ramirez A, Cailleau G, Fatton M, Dorador C, Junier P.	Front Microbiol	10.3389/fmicb.2022.826117	2022
Metabolism	Growth-Phase-Specific Modulation of Cell Morphology and Gene Expression by an Archaeal Histone Protein.	Dulmage KA, Todor H, Schmid AK.	mBio	10.1128/mbio.00649-15	2015
Metabolism	GvpE- and GvpD-mediated transcription regulation of the p-gvp genes encoding gas vesicles in Halobacterium salinarum.	Hofacker A, Schmitz KM, Cichonczyk A, Sartorius-Neef S, Pfeifer F.	Microbiology (Reading)	10.1099/mic.0.27078-0	2004
	tRNA derived small RNAs-Small players with big roles.	George S, Rafi M, Aldarmaki M, ElSiddig M, Al Nuaimi M, Amiri KMA.	Front Genet	10.3389/fgene.2022.997780	2022
Enzymology	Shotgun proteomics of the haloarchaeon Haloferax volcanii.	Kirkland PA, Humbard MA, Daniels CJ, Maupin-Furlow JA.	J Proteome Res	10.1021/pr800517a	2008
Metabolism	Threonyl-tRNA synthetase of archaea: importance of the discriminator base in the aminoacylation of threonine tRNA.	Ishikura H, Nagaoka Y, Yokozawa J, Umehara T, Kuno A, Hasegawa T.	Nucleic Acids Symp Ser	10.1093/nass/44.1.83	2000
Metabolism	Proteomic analysis of Haloferax volcanii reveals salinity-mediated regulation of the stress response protein PspA.	Bidle KA, Kirkland PA, Nannen JL, Maupin-Furlow JA.	Microbiology (Reading)	10.1099/mic.0.2007/015586-0	2008
	In vivo studies on putative Shine-Dalgarno sequences of the halophilic archaeon Halobacterium salinarum.	Sartorius-Neef S, Pfeifer F.	Mol Microbiol	10.1046/j.1365-2958.2003.03858.x	2004
Enzymology	Denitrification in hypersaline and coastal environments.	Torregrosa-Crespo J, Miralles-Robledillo JM, Bernabeu E, Pire C, Martinez-Espinosa RM.	FEMS Microbiol Lett	10.1093/femsle/fnad066	2023
	High level of intergenera gene exchange shapes the evolution of haloarchaea in an isolated Antarctic lake.	DeMaere MZ, Williams TJ, Allen MA, Brown MV, Gibson JA, Rich J, Lauro FM, Dyall-Smith M, Davenport KW, Woyke T, Kyrpides NC, Tringe SG, Cavicchioli R.	Proc Natl Acad Sci U S A	10.1073/pnas.1307090110	2013
	Characterization of RNA-based and protein-only RNases P from bacteria encoding both enzyme types.	Gossringer M, Waber NB, Wiegard JC, Hartmann RK.	RNA	10.1261/rna.079459.122	2023
Transcriptome	Survival characteristics and transcriptome profiling reveal the adaptive response of the Brucella melitensis 16M biofilm to osmotic stress.	Guo J, Zhu J, Zhao T, Sun Z, Song S, Zhang Y, Zhu D, Cao S, Deng X, Chai Y, Sun Y, Maratbek S, Chen C, Liu L, Zhang H.	Front Microbiol	10.3389/fmicb.2022.968592	2022
Metabolism	Mechanosensitive ion channels of the archaeon Haloferax volcanii.	Le Dain AC, Saint N, Kloda A, Ghazi A, Martinac B.	J Biol Chem	10.1074/jbc.273.20.12116	1998
Metabolism	Manual annotation, transcriptional analysis, and protein expression studies reveal novel genes in the agl cluster responsible for N glycosylation in the halophilic archaeon Haloferax volcanii.	Yurist-Doutsch S, Eichler J.	J Bacteriol	10.1128/jb.01838-08	2009
	The chaperonins: perspectives from the Archaea.	Lund PA, Large AT, Kapatai G.	Biochem Soc Trans	10.1042/bst0310681	2003
	Halolysin R4 of Haloferax mediterranei confers its host antagonistic and defensive activities.	Chen S, Sun S, Wang R, Feng H, Xiang H.	Appl Environ Microbiol	10.1128/aem.02889-20	2021
	Recent advances and perspectives in nucleotide second messenger signaling in bacteria.	Hengge R, Pruteanu M, Stulke J, Tschowri N, Turgay K.	Microlife	10.1093/femsml/uqad015	2023
	Characterization of a novel plasmid from extremely halophilic Archaea: nucleotide sequence and function analysis.	Ye X, Ou J, Ni L, Shi W, Shen P.	FEMS Microbiol Lett	10.1016/s0378-1097(03)00175-7	2003
	Unraveling Anaerobic Metabolisms in a Hypersaline Sediment.	Solchaga JI, Busalmen JP, Nercessian D.	Front Microbiol	10.3389/fmicb.2022.811432	2022
Enzymology	Isolation and characterization of dolichol-linked oligosaccharides from Haloferax volcanii.	Kuntz C, Sonnenbichler J, Sonnenbichler I, Sumper M, Zeitler R.	Glycobiology	10.1093/glycob/7.7.897	1997
	Engineering substrate promiscuity in 2,4-dichlorophenol hydroxylase by in silico design.	Wang Y, Zhang C, An S, Fang X, Yu D.	RSC Adv	10.1039/c8ra03229g	2018
Metabolism	Importance of the anticodon sequence in the aminoacylation of tRNAs by methionyl-tRNA synthetase and by valyl-tRNA synthetase in an Archaebacterium.	Ramesh V, RajBhandary UL.	J Biol Chem	10.1074/jbc.m008206200	2001
Enzymology	Genetic evidence for a novel thymidylate synthase in the halophilic archaeon Halobacterium salinarum and in Campylobacter jejuni.	Giladi M, Bitan-Banin G, Mevarech M, Ortenberg R.	FEMS Microbiol Lett	10.1111/j.1574-6968.2002.tb11422.x	2002
Metabolism	Glycerol-mediated repression of glucose metabolism and glycerol kinase as the sole route of glycerol catabolism in the haloarchaeon Haloferax volcanii.	Sherwood KE, Cano DJ, Maupin-Furlow JA.	J Bacteriol	10.1128/jb.00131-09	2009
Metabolism	Genetic and biochemical analysis of the twin-arginine translocation pathway in halophilic archaea.	Dilks K, Gimenez MI, Pohlschroder M.	J Bacteriol	10.1128/jb.187.23.8104-8113.2005	2005
Enzymology	Molecular cloning of A1-ATPase gene from extremely halophilic archaeon Haloarcula japonica strain TR-1.	Yatsunami R, Iwamoto M, Ihara K, Nakamura S.	Nucleic Acids Symp Ser	10.1093/nass/42.1.75	1999
Metabolism	Activity and transcriptional regulation of bacterial protein-like glycerol-3-phosphate dehydrogenase of the haloarchaea in Haloferax volcanii.	Rawls KS, Martin JH, Maupin-Furlow JA.	J Bacteriol	10.1128/jb.00276-11	2011
	Mre11-Rad50 promotes rapid repair of DNA damage in the polyploid archaeon Haloferax volcanii by restraining homologous recombination.	Delmas S, Shunburne L, Ngo HP, Allers T.	PLoS Genet	10.1371/journal.pgen.1000552	2009
	Identification of the 3-amino-3-carboxypropyl (acp) transferase enzyme responsible for acp3U formation at position 47 in Escherichia coli tRNAs.	Meyer B, Immer C, Kaiser S, Sharma S, Yang J, Watzinger P, Weiss L, Kotter A, Helm M, Seitz HM, Kotter P, Kellner S, Entian KD, Wohnert J.	Nucleic Acids Res	10.1093/nar/gkz1191	2020
Metabolism	Regulation of gas vesicle formation in halophilic archaea.	Pfeifer F, Gregor D, Hofacker A, Plosser P, Zimmermann P.	J Mol Microbiol Biotechnol		2002
	Heavily Armed Ancestors: CRISPR Immunity and Applications in Archaea with a Comparative Analysis of CRISPR Types in Sulfolobales.	Zink IA, Wimmer E, Schleper C.	Biomolecules	10.3390/biom10111523	2020
	Is phosphatidylglycerol essential for terrestrial life?	Furse S.	J Chem Biol	10.1007/s12154-016-0159-3	2017
	Polyploidy in haloarchaea: advantages for growth and survival.	Zerulla K, Soppa J.	Front Microbiol	10.3389/fmicb.2014.00274	2014
	The sequence of the major gas vesicle protein, GvpA, influences the width and strength of halobacterial gas vesicles.	Beard SJ, Hayes PK, Pfeifer F, Walsby AE.	FEMS Microbiol Lett	10.1111/j.1574-6968.2002.tb11299.x	2002
Enzymology	Gentisate 1,2-dioxygenase from Haloferax sp. D1227.	Fu W, Oriel P.	Extremophiles	10.1007/s007920050090	1998
	A homozygous truncating mutation in PUS3 expands the role of tRNA modification in normal cognition.	Shaheen R, Han L, Faqeih E, Ewida N, Alobeid E, Phizicky EM, Alkuraya FS.	Hum Genet	10.1007/s00439-016-1665-7	2016
Enzymology	Characterization of RNase P holoenzymes from Methanococcus jannaschii and Methanothermobacter thermoautotrophicus.	Andrews AJ, Hall TA, Brown JW.	Biol Chem	10.1515/bc.2001.147	2001
Metabolism	Major and minor crRNA annealing sites facilitate low stringency DNA protospacer binding prior to Type I-A CRISPR-Cas interference in Sulfolobus.	Mousaei M, Deng L, She Q, Garrett RA.	RNA Biol	10.1080/15476286.2016.1229735	2016
Metabolism	In Silico Analysis of the Enzymes Involved in Haloarchaeal Denitrification.	Bernabeu E, Miralles-Robledillo JM, Giani M, Valdes E, Martinez-Espinosa RM, Pire C.	Biomolecules	10.3390/biom11071043	2021
Transcriptome	Large-scale sequence comparisons with sourmash.	Pierce NT, Irber L, Reiter T, Brooks P, Brown CT.	F1000Res	10.12688/f1000research.19675.1	2019
Metabolism	Mechanistic insights into Lhr helicase function in DNA repair.	Buckley RJ, Kramm K, Cooper CDO, Grohmann D, Bolt EL.	Biochem J	10.1042/bcj20200379	2020
Enzymology	Site-directed mutagenesis and halophilicity of dihydrolipoamide dehydrogenase from the halophilic archaeon, Haloferax volcanii.	Jolley KA, Russell RJ, Hough DW, Danson MJ.	Eur J Biochem	10.1111/j.1432-1033.1997.00362.x	1997
Metabolism	The Pentose Phosphate Pathway in Yeasts-More Than a Poor Cousin of Glycolysis.	Bertels LK, Fernandez Murillo L, Heinisch JJ.	Biomolecules	10.3390/biom11050725	2021
Metabolism	Substrate promiscuity: AglB, the archaeal oligosaccharyltransferase, can process a variety of lipid-linked glycans.	Cohen-Rosenzweig C, Guan Z, Shaanan B, Eichler J.	Appl Environ Microbiol	10.1128/aem.03191-13	2014
Metabolism	Culture in the presence of sugars increases activity of multi-drug efflux transporter on Haloferax volcanii.	Miyauchi S, Tanabu S, Abe A, Okumura R, Kamo N.	Microb Drug Resist	10.1089/mdr.1997.3.359	1997
	Surviving salt fluctuations: stress and recovery in Halobacterium salinarum, an extreme halophilic Archaeon.	Vauclare P, Natali F, Kleman JP, Zaccai G, Franzetti B.	Sci Rep	10.1038/s41598-020-59681-1	2020
Enzymology	Recombinant production of Zymomonas mobilis pyruvate decarboxylase in the haloarchaeon Haloferax volcanii.	Kaczowka SJ, Reuter CJ, Talarico LA, Maupin-Furlow JA.	Archaea	10.1155/2005/325738	2005
Enzymology	Biochemical Pathways Leading to the Formation of Wyosine Derivatives in tRNA of Archaea.	Urbonavicius J, Tauraite D.	Biomolecules	10.3390/biom10121627	2020
Enzymology	Structural features of halophilicity derived from the crystal structure of dihydrofolate reductase from the Dead Sea halophilic archaeon, Haloferax volcanii.	Pieper U, Kapadia G, Mevarech M, Herzberg O.	Structure	10.1016/s0969-2126(98)00009-4	1998
Metabolism	Oxygen Generation via Water Splitting by a Novel Biogenic Metal Ion-Binding Compound.	Dershwitz P, Bandow NL, Yang J, Semrau JD, McEllistrem MT, Heinze RA, Fonseca M, Ledesma JC, Jennett JR, DiSpirito AM, Athwal NS, Hargrove MS, Bobik TA, Zischka H, DiSpirito AA.	Appl Environ Microbiol	10.1128/aem.00286-21	2021
Genetics	Selection-free markerless genome manipulations in the polyploid bacterium Thermus thermophilus.	Li H.	3 Biotech	10.1007/s13205-019-1682-z	2019
Metabolism	Defining the topology of the N-glycosylation pathway in the halophilic archaeon Haloferax volcanii.	Plavner N, Eichler J.	J Bacteriol	10.1128/jb.01200-08	2008
Enzymology	Trm112, a Protein Activator of Methyltransferases Modifying Actors of the Eukaryotic Translational Apparatus.	Bourgeois G, Letoquart J, van Tran N, Graille M.	Biomolecules	10.3390/biom7010007	2017
Genetics	Protospacer-Adjacent Motif Specificity during Clostridioides difficile Type I-B CRISPR-Cas Interference and Adaptation.	Maikova A, Boudry P, Shiriaeva A, Vasileva A, Boutserin A, Medvedeva S, Semenova E, Severinov K, Soutourina O.	mBio	10.1128/mbio.02136-21	2021
Genetics	Functional genomic and advanced genetic studies reveal novel insights into the metabolism, regulation, and biology of Haloferax volcanii.	Soppa J.	Archaea	10.1155/2011/602408	2011
	Geochemical constraints on the Hadean environment from mineral fingerprints of prokaryotes.	Novoselov AA, Silva D, Schneider J, Abrevaya XC, Chaffin MS, Serrano P, Navarro MS, Conti MJ, Souza Filho CR.	Sci Rep	10.1038/s41598-017-04161-2	2017
Metabolism	Identification of AglE, a second glycosyltransferase involved in N glycosylation of the Haloferax volcanii S-layer glycoprotein.	Abu-Qarn M, Giordano A, Battaglia F, Trauner A, Hitchen PG, Morris HR, Dell A, Eichler J.	J Bacteriol	10.1128/jb.00056-08	2008
	Characterization and repurposing of the endogenous Type I-F CRISPR-Cas system of Zymomonas mobilis for genome engineering.	Zheng Y, Han J, Wang B, Hu X, Li R, Shen W, Ma X, Ma L, Yi L, Yang S, Peng W.	Nucleic Acids Res	10.1093/nar/gkz940	2019
Metabolism	Recognition of tRNA by aminoacyl-tRNA synthetase from hyperthermophilic archaea, Aeropyrum pernix K1.	Yokozawa J, Nagaoka Y, Umehara T, Iwaki J, Kawarabayasi Y, Koyama Y, Sako Y, Wakagi T, Kuno A, Hasegawa T.	Nucleic Acids Res Suppl	10.1093/nass/1.1.117	2001
Metabolism	N-glycosylation of Haloferax volcanii flagellins requires known Agl proteins and is essential for biosynthesis of stable flagella.	Tripepi M, You J, Temel S, Onder O, Brisson D, Pohlschroder M.	J Bacteriol	10.1128/jb.00731-12	2012
Metabolism	RNA splicing ligase activity in the archaeon Haloferax volcanii.	Gomes I, Gupta R.	Biochem Biophys Res Commun	10.1006/bbrc.1997.7193	1997
Metabolism	Splicing of intron-containing tRNATrp by the archaeon Haloferax volcanii occurs independent of mature tRNA structure.	Armbruster DW, Daniels CJ.	J Biol Chem	10.1074/jbc.272.32.19758	1997
	Identifying Components of a Halobacterium salinarum N-Glycosylation Pathway.	Vershinin Z, Zaretsky M, Guan Z, Eichler J.	Front Microbiol	10.3389/fmicb.2021.779599	2021
	Metabolomic Profile of the Fungus Cryomyces antarcticus Under Simulated Martian and Space Conditions as Support for Life-Detection Missions on Mars.	Gevi F, Leo P, Cassaro A, Pacelli C, de Vera JP, Rabbow E, Timperio AM, Onofri S.	Front Microbiol	10.3389/fmicb.2022.749396	2022
	Molecular acclimation of Halobacterium salinarum to halite brine inclusions.	Favreau C, Tribondeau A, Marugan M, Guyot F, Alpha-Bazin B, Marie A, Puppo R, Dufour T, Huguet A, Zirah S, Kish A.	Front Microbiol	10.3389/fmicb.2022.1075274	2022
	Gene deletions leading to a reduction in the number of cyclopentane rings in Sulfolobus acidocaldarius tetraether lipids.	Guan Z, Delago A, Nussbaum P, Meyer BH, Albers SV, Eichler J.	FEMS Microbiol Lett	10.1093/femsle/fnx250	2018
	A CRISPRi-dCas9 System for Archaea and Its Use To Examine Gene Function during Nitrogen Fixation by Methanosarcina acetivorans.	Dhamad AE, Lessner DJ.	Appl Environ Microbiol	10.1128/aem.01402-20	2020
	The nuts and bolts of the Haloferax CRISPR-Cas system I-B.	Maier LK, Stachler AE, Brendel J, Stoll B, Fischer S, Haas KA, Schwarz TS, Alkhnbashi OS, Sharma K, Urlaub H, Backofen R, Gophna U, Marchfelder A.	RNA Biol	10.1080/15476286.2018.1460994	2019
	Crystal structures and insights into precursor tRNA 5'-end processing by prokaryotic minimal protein-only RNase P.	Li Y, Su S, Gao Y, Lu G, Liu H, Chen X, Shao Z, Zhang Y, Shao Q, Zhao X, Yang J, Cao C, Lin J, Ma J, Gan J.	Nat Commun	10.1038/s41467-022-30072-6	2022
	Ancestral archaea expanded the genetic code with pyrrolysine.	Guo LT, Amikura K, Jiang HK, Mukai T, Fu X, Wang YS, O'Donoghue P, Soll D, Tharp JM.	J Biol Chem	10.1016/j.jbc.2022.102521	2022
	Coarse-grain simulations on NMR conformational ensembles highlight functional residues in proteins.	Sacquin-Mora S.	J R Soc Interface	10.1098/rsif.2019.0075	2019
Biotechnology	Assessing the genetic diversity of Cu resistance in mine tailings through high-throughput recovery of full-length copA genes.	Li X, Zhu YG, Shaban B, Bruxner TJ, Bond PL, Huang L.	Sci Rep	10.1038/srep13258	2015
	Modeling protein quaternary structure of homo- and hetero-oligomers beyond binary interactions by homology.	Bertoni M, Kiefer F, Biasini M, Bordoli L, Schwede T.	Sci Rep	10.1038/s41598-017-09654-8	2017
	Construction and analysis of a recombination-deficient (radA) mutant of Haloferax volcanii.	Woods WG, Dyall-Smith ML.	Mol Microbiol	10.1046/j.1365-2958.1997.2651626.x	1997
	Recombinogenic properties of Pyrococcus furiosus strain COM1 enable rapid selection of targeted mutants.	Farkas J, Stirrett K, Lipscomb GL, Nixon W, Scott RA, Adams MW, Adams MW, Westpheling J.	Appl Environ Microbiol	10.1128/aem.00936-12	2012
Enzymology	Cloning, Expression and Characterization of UDP-Glucose Dehydrogenases.	Couto MR, Rodrigues JL, Rodrigues LR.	Life (Basel)	10.3390/life11111201	2021
	Small regulatory RNAs in Archaea.	Babski J, Maier LK, Heyer R, Jaschinski K, Prasse D, Jager D, Randau L, Schmitz RA, Marchfelder A, Soppa J.	RNA Biol	10.4161/rna.28452	2014
	Cloning and sequencing of ftsZ homolog from extremely halophilic archaeon Haloarcula japonica strain TR-1.	Kazumichi O, Yatsunami R, Nakamura S.	Nucleic Acids Symp Ser	10.1093/nass/44.1.155	2000
Metabolism	LccA, an archaeal laccase secreted as a highly stable glycoprotein into the extracellular medium by Haloferax volcanii.	Uthandi S, Saad B, Humbard MA, Maupin-Furlow JA.	Appl Environ Microbiol	10.1128/aem.01757-09	2010
Enzymology	Haloferax mediterranei, an Archaeal Model for Denitrification in Saline Systems, Characterized Through Integrated Physiological and Transcriptional Analyses.	Torregrosa-Crespo J, Pire C, Bergaust L, Martinez-Espinosa RM.	Front Microbiol	10.3389/fmicb.2020.00768	2020
Metabolism	A 5-formyltetrahydrofolate cycloligase paralog from all domains of life: comparative genomic and experimental evidence for a cryptic role in thiamin metabolism.	Pribat A, Blaby IK, Lara-Nunez A, Jeanguenin L, Fouquet R, Frelin O, Gregory JF, Philmus B, Begley TP, de Crecy-Lagard V, Hanson AD.	Funct Integr Genomics	10.1007/s10142-011-0224-5	2011
	Nitrogen as the major factor influencing gene expression in Yarrowia lipolytica.	Hapeta P, Kerkhoven EJ, Lazar Z.	Biotechnol Rep (Amst)	10.1016/j.btre.2020.e00521	2020
	The proteasome controls ESCRT-III-mediated cell division in an archaeon.	Tarrason Risa G, Hurtig F, Bray S, Hafner AE, Harker-Kirschneck L, Faull P, Davis C, Papatziamou D, Mutavchiev DR, Fan C, Meneguello L, Arashiro Pulschen A, Dey G, Culley S, Kilkenny M, Souza DP, Pellegrini L, de Bruin RAM, Henriques R, Snijders AP, Saric A, Lindas AC, Robinson NP, Baum B.	Science	10.1126/science.aaz2532	2020
	Use of a halobacterial bgaH reporter gene to analyse the regulation of gene expression in halophilic archaea.	Gregor D, Pfeifer F.	Microbiology (Reading)	10.1099/00221287-147-7-1745	2001
	Biofilm Formation by ica-Negative Ocular Isolates of Staphylococcus haemolyticus.	Panda S, Singh DV.	Front Microbiol	10.3389/fmicb.2018.02687	2018
Enzymology	Biochemical characterisation of LigN, an NAD+-dependent DNA ligase from the halophilic euryarchaeon Haloferax volcanii that displays maximal in vitro activity at high salt concentrations.	Poidevin L, MacNeill SA.	BMC Mol Biol	10.1186/1471-2199-7-44	2006
Metabolism	Defining the influence of Rad51 and Dmc1 lineage-specific amino acids on genetic recombination.	Steinfeld JB, Belan O, Kwon Y, Terakawa T, Al-Zain A, Smith MJ, Crickard JB, Qi Z, Zhao W, Rothstein R, Symington LS, Sung P, Boulton SJ, Greene EC.	Genes Dev	10.1101/gad.328062.119	2019
	The repair of ultraviolet light-induced DNA damage in the halophilic archaebacteria, Halobacterium cutirubrum, Halobacterium halobium and Haloferax volcanii.	McCready S.	Mutat Res	10.1016/0921-8777(96)00018-3	1996
Metabolism	A regulatory RNA is involved in RNA duplex formation and biofilm regulation in Sulfolobus acidocaldarius.	Orell A, Tripp V, Aliaga-Tobar V, Albers SV, Maracaja-Coutinho V, Randau L.	Nucleic Acids Res	10.1093/nar/gky144	2018
	Voltage-dependent porin-like ion channels in the archaeon Haloferax volcanii.	Besnard M, Martinac B, Ghazi A.	J Biol Chem	10.1074/jbc.272.2.992	1997
Metabolism	Aminoacyl-tRNA synthesis in Archaea.	Ibba M, Celic I, Curnow A, Kim H, Pelaschier J, Tumbula D, Vothknecht U, Woese C, Soll D.	Nucleic Acids Symp Ser		1997
	Biofilm formation by haloarchaea.	Frols S, Dyall-Smith M, Pfeifer F	Environ Microbiol	10.1111/j.1462-2920.2012.02895.x	2012
Metabolism	Identification of polyhydroxyalkanoates in Halococcus and other haloarchaeal species.	Legat A, Gruber C, Zangger K, Wanner G, Stan-Lotter H	Appl Microbiol Biotechnol	10.1007/s00253-010-2611-6	2010
Genetics	Haloferax massiliensis sp. nov., the first human-associated halophilic archaea.	Khelaifia S, Raoult D.	New Microbes New Infect	10.1016/j.nmni.2016.05.007	2016
Phylogeny	Taxonomic characterization of Haloferax sp. (" H. alicantei") strain Aa 2.2: description of Haloferax lucentensis sp. nov.	Gutierrez MC, Kamekura M, Holmes ML, Dyall-Smith ML, Ventosa A.	Extremophiles	10.1007/s00792-002-0282-7	2002
Metabolism	Haloferax alexandrinus sp. nov., an extremely halophilic canthaxanthin-producing archaeon from a solar saltern in Alexandria (Egypt).	Asker D, Ohta Y.	Int J Syst Evol Microbiol	10.1099/00207713-52-3-729	2002

References

#1343	Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 3757
#20215	Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 )
#66792	Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) .
#66794	Antje Chang, Lisa Jeske, Sandra Ulbrich, Julia Hofmann, Julia Koblitz, Ida Schomburg, Meina Neumann-Schaal, Dieter Jahn, Dietmar Schomburg: BRENDA, the ELIXIR core data resource in 2021: new developments and updates. Nucleic Acids Res. 49: D498 - D508 2020 ( DOI 10.1093/nar/gkaa1025 , PubMed 33211880 )
#67770	Japan Collection of Microorganism (JCM) ; Curators of the JCM;
#69479	João F Matias Rodrigues, Janko Tackmann,Gregor Rot, Thomas SB Schmidt, Lukas Malfertheiner, Mihai Danaila,Marija Dmitrijeva, Daniela Gaio, Nicolas Näpflin and Christian von Mering. University of Zurich.: MicrobeAtlas 1.0 beta .
#125438	Julia Koblitz, Lorenz Christian Reimer, Rüdiger Pukall, Jörg Overmann: Predicting bacterial phenotypic traits through improved machine learning using high-quality, curated datasets. 2024 ( DOI 10.1101/2024.08.12.607695 )
#125439	Philipp Münch, René Mreches, Martin Binder, Hüseyin Anil Gündüz, Xiao-Yin To, Alice McHardy: deepG: Deep Learning for Genome Sequence Data. R package version 0.3.1 .
#126262	A. Lissin, I. Schober, J. F. Witte, H. Lüken, A. Podstawka, J. Koblitz, B. Bunk, P. Dawyndt, P. Vandamme, P. de Vos, J. Overmann, L. C. Reimer: StrainInfo—the central database for linked microbial strain identifiers. ( DOI 10.1093/database/baaf059 )

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Haloferax volcanii (DSM 3757, ATCC 29605, CCM 2852)

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