Geodermatophilus obscurus (CCUG 61914, KCTC 9177, DSM 43160)

Cell morphology

Colony morphology

Multicellular morphology

Multimedia

• @ref:	10828
  multimedia content:	DSM_43160.jpg
  multimedia.multimedia content:	https://www.dsmz.de/microorganisms/photos/DSM_43160.jpg
  caption:	Medium 65 28°C
  intellectual property rights:	© Leibniz-Institut DSMZ
  manual_annotation:	1

• @ref:	66793
  multimedia content:	EM_DSM_43160_1.jpg
  multimedia.multimedia content:	EM_DSM_43160_1.jpg
  caption:	electron microscopic image
  intellectual property rights:	© HZI/Manfred Rohde
  manual_annotation:	1

Culture medium

@ref	Name	Growth	Medium link	Composition
19943	ISP 2			Name: ISP 2 / Yeast Malt Agar (5265); 5265 Composition Malt extract 10.0 g/l Yeast extract 4.0 g/l Glucose 4.0 g/l Agar 15.0 g/l Preparation: Sterilisation: 20 minutes at 121°C pH before sterilisation: 7.0 Usage: Maintenance and Taxonomy Organisms: All Actinomycetes
19943	ISP 3			Name: ISP 3; 5315 Composition Dog oat flakes 20.0 g/l Trace element solution (5314) 2.5 ml/l Agar 18.0 g/l Preparation: Oat flakes are cooked for 20 minutes, trace element solution and agar are added (in the case of non rolled oat flakes the suspension has to bee filtrated). Sterilisation: 20 minutes at 121°C pH before sterilisation: 7.8 Usage: Maintenance and taxonomy (e.g. SEM As liquid medium for metabolite production) Organisms: All Actinomycetes Trace element solution 5314 Name: Trace element solution 5314; 5314 Composition CaCl2 x H2O 3.0 g/l Fe-III-citrate 1.0 g/l MnSO4 0.2 g/l ZnCl2 0.1 g/l CuSO4 x 5 H2O 0.025 g/l Sodium tetra borate 0.2 g/l CoCl2 x 6 H2O 0.004 g/l Sodium molybdate 0.01 g/l Preparation: Use double destillated water. Sterilisation: 20 minutes at 121°C pH before sterilisation: Usage: Trace element solution for different media Organisms:
19943	ISP 4			Name: ISP 4; DSM 547 Solution I: Difco soluble starch, 10.0 g. Make a paste of the starch with a small amount of cold distilled water and bring to a volume of 500 ml. Solution II: CaCO3 2.0 g K2HPO4 (anhydrous) 1.0 g MgSO4 x 7 H2O 1.0 g NaCl 1.0 g (NH4)2SO4 2.0 g Distilled water 500.0 ml Trace salt solution (see below) 1.0 ml The pH should be between 7.0 and 7.4. Do not adjust if it is within this range. Mix solutions I and II together. Add 20.0 g agar. Liquify agar by steaming at 100°C for 10 to 20 min. Trace element solution: FeSO4 x 7 H2O 0.1 g MnCl2 x 4 H2O 0.1 g ZnSO4 x 7 H2O 0.1 g Distilled water 100.0 ml
19943	ISP 5			Name: ISP 5 (5323) Composition L-Asparagine 1.0 g/l Glycerol 10.0 g/l K2HPO4 1.0 g/l Salt solution (see preparation) 1.0 ml/l Agar 20.0 g/l Preparation: Salt solution 1.0 g FeSO4 x 7 H2O 1.0 g MnCl2 x 4 H2O 1.0 g ZNSO4 x 7 H2O in 100 ml water Sterilisation: 20 minutes at 121°C pH before sterilisation: 7.2 Usage: Maintenance and taxonomy Organisms: All Actinomycetes
19943	ISP 6			Name: ISP 6 (5318) Composition Peptone 15.0 g/l Proteose peptose 5.0 g/l Ferric ammonium citrate 0.5 g/l Sodium glycerophosphate 1.0 g/l Sodium thiosulfate 0.08 g/l Yeast extract 1.0 g/l Agar 15.0 g/l Sterilisation: 20 minutes at 121°C pH before sterilisation: Usage: Production of melanoid pigments Organisms: All Actinomycetes
19943	ISP 7			Name: ISP 7 (5322) Composition Glycerol 15.0 g/l L-Tyrosine 0.5 g/l L-Asparagine 1.0 g/l K2HPO4 0.5 g/l NaCl 0.5 g/l FeSO4 x 7 H2O 0.01 g/l Trace element solution 5343 1.0 ml/l Agar 20.0 Sterilisation: 20 minutes at 121°C pH before sterilisation: 7.3 Usage: Production of melanoid pigments Organisms: All Actinomycetes
10828	GYM STREPTOMYCES MEDIUM (DSMZ Medium 65)		Medium recipe at MediaDive	Name: GYM STREPTOMYCES MEDIUM (DSMZ Medium 65) Composition: Agar 18.0 g/l Malt extract 10.0 g/l Yeast extract 4.0 g/l Glucose 4.0 g/l CaCO3 2.0 g/l Distilled water
10828	GPHF-MEDIUM (DSMZ Medium 553)		Medium recipe at MediaDive	Name: GPHF-MEDIUM (DSMZ Medium 553) Composition: Agar 20.0 g/l Glucose 10.0 g/l Beef extract 5.0 g/l Yeast extract 5.0 g/l Casein peptone 5.0 g/l CaCl2 x 2 H2O 0.74 g/l Distilled water
10828	CZAPEK PEPTONE AGAR (DSMZ Medium 83)		Medium recipe at MediaDive	Name: CZAPEK PEPTONE AGAR (DSMZ Medium 83) Composition: Sucrose 30.0 g/l Agar 20.0 g/l Peptone 5.0 g/l NaNO3 3.0 g/l Yeast extract 2.0 g/l K2HPO4 1.0 g/l MgSO4 x 7 H2O 0.5 g/l KCl 0.5 g/l FeSO4 x 7 H2O 0.01 g/l Distilled water

Culture temp

Oxygen tolerance

Halophily

Observation

Metabolite utilization

@ref	Chebi-ID	Metabolite	Utilization activity	Kind of utilization tested
19943	22599 ChEBI	arabinose	+
68368	29016 ChEBI	arginine	+	hydrolysis	from API 20E
19943	62968 ChEBI	cellulose	+
68368	16947 ChEBI	citrate	+	assimilation	from API 20E
19943	28757 ChEBI	fructose	+
68368	5291 ChEBI	gelatin	-	hydrolysis	from API 20E
19943	17234 ChEBI	glucose	+
68368	25094 ChEBI	lysine	+	degradation	from API 20E
19943	29864 ChEBI	mannitol	+
19943	17268 ChEBI	myo-inositol	+
68368	18257 ChEBI	ornithine	+	degradation	from API 20E
19943	16634 ChEBI	raffinose	+
19943	26546 ChEBI	rhamnose	+
19943	17992 ChEBI	sucrose	+
68368	27897 ChEBI	tryptophan	-	energy source	from API 20E
68368	16199 ChEBI	urea	+	hydrolysis	from API 20E
19943	18222 ChEBI	xylose	+

Metabolite production

@ref	Chebi-ID	Metabolite	Production
68368	15688 ChEBI	acetoin		from API 20E
68368	16136 ChEBI	hydrogen sulfide		from API 20E
68368	35581 ChEBI	indole		from API 20E

Metabolite tests

@ref	Chebi-ID	Metabolite	Voges-proskauer-test	Indole test
68368	15688 ChEBI	acetoin	+		from API 20E
68368	35581 ChEBI	indole		-	from API 20E

Enzymes

@ref	Value	Activity	Ec
68382	acid phosphatase	+	3.1.3.2	from API zym
68382	alkaline phosphatase	+	3.1.3.1	from API zym
68382	alpha-chymotrypsin	+	3.4.21.1	from API zym
68382	alpha-fucosidase	-	3.2.1.51	from API zym
68382	alpha-galactosidase	-	3.2.1.22	from API zym
68382	alpha-glucosidase	+	3.2.1.20	from API zym
68382	alpha-mannosidase	-	3.2.1.24	from API zym
68368	arginine dihydrolase	+	3.5.3.6	from API 20E
68382	beta-galactosidase	-	3.2.1.23	from API zym
68368	beta-galactosidase	-	3.2.1.23	from API 20E
68382	beta-glucosidase	-	3.2.1.21	from API zym
68382	beta-glucuronidase	-	3.2.1.31	from API zym
68382	cystine arylamidase	-	3.4.11.3	from API zym
68382	esterase (C 4)	+		from API zym
68382	esterase lipase (C 8)	+		from API zym
68368	gelatinase	-		from API 20E
68382	leucine arylamidase	+	3.4.11.1	from API zym
68382	lipase (C 14)	-		from API zym
68368	lysine decarboxylase	+	4.1.1.18	from API 20E
68382	N-acetyl-beta-glucosaminidase	-	3.2.1.52	from API zym
68382	naphthol-AS-BI-phosphohydrolase	-		from API zym
68368	ornithine decarboxylase	+	4.1.1.17	from API 20E
68382	trypsin	+	3.4.21.4	from API zym
68368	tryptophan deaminase	-	4.1.99.1	from API 20E
68368	urease	+	3.5.1.5	from API 20E
68382	valine arylamidase	+		from API zym

Pathway annotation

Computationally determined by

@ref	pathway	enzyme coverage	annotated reactions	external links
66794	adipate degradation	100	2 of 2
66794	cardiolipin biosynthesis	100	7 of 7
66794	starch degradation	100	10 of 10
66794	cis-vaccenate biosynthesis	100	2 of 2
66794	L-lactaldehyde degradation	100	3 of 3
66794	molybdenum cofactor biosynthesis	100	9 of 9
66794	phenylacetate degradation (aerobic)	100	5 of 5
66794	UDP-GlcNAc biosynthesis	100	3 of 3
66794	CDP-diacylglycerol biosynthesis	100	2 of 2
66794	reductive acetyl coenzyme A pathway	100	7 of 7
66794	vitamin K metabolism	100	5 of 5
66794	coenzyme A metabolism	100	4 of 4
66794	formaldehyde oxidation	100	3 of 3
66794	4-hydroxymandelate degradation	100	9 of 9
66794	glycine betaine biosynthesis	100	5 of 5
66794	anapleurotic synthesis of oxalacetate	100	1 of 1
66794	palmitate biosynthesis	100	22 of 22
66794	folate polyglutamylation	100	1 of 1
66794	taurine degradation	100	1 of 1
66794	ethanol fermentation	100	2 of 2
66794	suberin monomers biosynthesis	100	2 of 2
66794	IAA biosynthesis	100	3 of 3
66794	ppGpp biosynthesis	100	4 of 4
66794	lactate fermentation	100	4 of 4
66794	methylglyoxal degradation	100	5 of 5
66794	photosynthesis	92.86	13 of 14
66794	glutathione metabolism	92.86	13 of 14
66794	citric acid cycle	92.86	13 of 14
66794	leucine metabolism	92.31	12 of 13
66794	phenylalanine metabolism	92.31	12 of 13
66794	pentose phosphate pathway	90.91	10 of 11
66794	Entner Doudoroff pathway	90	9 of 10
66794	threonine metabolism	90	9 of 10
66794	myo-inositol biosynthesis	90	9 of 10
66794	valine metabolism	88.89	8 of 9
66794	CO2 fixation in Crenarchaeota	88.89	8 of 9
66794	chorismate metabolism	88.89	8 of 9
66794	NAD metabolism	88.89	16 of 18
66794	aspartate and asparagine metabolism	88.89	8 of 9
66794	vitamin B12 metabolism	88.24	30 of 34
66794	C4 and CAM-carbon fixation	87.5	7 of 8
66794	gluconeogenesis	87.5	7 of 8
66794	isoleucine metabolism	87.5	7 of 8
66794	propanol degradation	85.71	6 of 7
66794	degradation of sugar acids	84	21 of 25
66794	degradation of aromatic, nitrogen containing compounds	83.33	10 of 12
66794	glycolate and glyoxylate degradation	83.33	5 of 6
66794	glycolysis	82.35	14 of 17
66794	glutamate and glutamine metabolism	82.14	23 of 28
66794	proline metabolism	81.82	9 of 11
66794	propionate fermentation	80	8 of 10
66794	flavin biosynthesis	80	12 of 15
66794	creatinine degradation	80	4 of 5
66794	cellulose degradation	80	4 of 5
66794	ethylmalonyl-CoA pathway	80	4 of 5
66794	glycogen metabolism	80	4 of 5
66794	factor 420 biosynthesis	80	4 of 5
66794	peptidoglycan biosynthesis	80	12 of 15
66794	3-chlorocatechol degradation	80	4 of 5
66794	alanine metabolism	79.31	23 of 29
66794	arginine metabolism	79.17	19 of 24
66794	tryptophan metabolism	78.95	30 of 38
66794	heme metabolism	78.57	11 of 14
66794	serine metabolism	77.78	7 of 9
66794	purine metabolism	77.66	73 of 94
66794	urea cycle	76.92	10 of 13
66794	sulfopterin metabolism	75	3 of 4
66794	dTDPLrhamnose biosynthesis	75	6 of 8
66794	glycogen biosynthesis	75	3 of 4
66794	ketogluconate metabolism	75	6 of 8
66794	cyclohexanol degradation	75	3 of 4
66794	butanoate fermentation	75	3 of 4
66794	acetate fermentation	75	3 of 4
66794	degradation of pentoses	75	21 of 28
66794	lipid metabolism	74.19	23 of 31
66794	pyrimidine metabolism	73.33	33 of 45
66794	metabolism of disaccharids	72.73	8 of 11
66794	tetrahydrofolate metabolism	71.43	10 of 14
66794	ubiquinone biosynthesis	71.43	5 of 7
66794	isoprenoid biosynthesis	69.23	18 of 26
66794	vitamin B1 metabolism	69.23	9 of 13
66794	histidine metabolism	68.97	20 of 29
66794	octane oxidation	66.67	2 of 3
66794	methane metabolism	66.67	2 of 3
66794	enterobactin biosynthesis	66.67	2 of 3
66794	allantoin degradation	66.67	6 of 9
66794	selenocysteine biosynthesis	66.67	4 of 6
66794	acetoin degradation	66.67	2 of 3
66794	lysine metabolism	66.67	28 of 42
66794	cyanate degradation	66.67	2 of 3
66794	cysteine metabolism	66.67	12 of 18
66794	oxidative phosphorylation	65.93	60 of 91
66794	non-pathway related	65.79	25 of 38
66794	methionine metabolism	65.38	17 of 26
66794	6-hydroxymethyl-dihydropterin diphosphate biosynthesis	62.5	5 of 8
66794	degradation of sugar alcohols	62.5	10 of 16
66794	degradation of hexoses	61.11	11 of 18
66794	gallate degradation	60	3 of 5
66794	tyrosine metabolism	57.14	8 of 14
66794	androgen and estrogen metabolism	56.25	9 of 16
66794	d-mannose degradation	55.56	5 of 9
66794	lipid A biosynthesis	55.56	5 of 9
66794	nitrate assimilation	55.56	5 of 9
66794	phenol degradation	55	11 of 20
66794	carotenoid biosynthesis	54.55	12 of 22
66794	3-phenylpropionate degradation	53.33	8 of 15
66794	ribulose monophosphate pathway	50	1 of 2
66794	aminopropanol phosphate biosynthesis	50	1 of 2
66794	pantothenate biosynthesis	50	3 of 6
66794	coenzyme M biosynthesis	50	5 of 10
66794	kanosamine biosynthesis II	50	1 of 2
66794	toluene degradation	50	2 of 4
66794	resorcinol degradation	50	1 of 2
66794	biotin biosynthesis	50	2 of 4
66794	sphingosine metabolism	50	3 of 6
66794	mannosylglycerate biosynthesis	50	1 of 2
66794	bile acid biosynthesis, neutral pathway	47.06	8 of 17
66794	d-xylose degradation	45.45	5 of 11
66794	vitamin B6 metabolism	45.45	5 of 11
66794	arachidonic acid metabolism	44.44	8 of 18
66794	benzoyl-CoA degradation	42.86	3 of 7
66794	glycine metabolism	40	4 of 10
66794	lipoate biosynthesis	40	2 of 5
66794	arachidonate biosynthesis	40	2 of 5
66794	D-cycloserine biosynthesis	40	2 of 5
66794	O-antigen biosynthesis	40	2 of 5
66794	4-hydroxyphenylacetate degradation	40	4 of 10
66794	sulfate reduction	38.46	5 of 13
66794	phosphatidylethanolamine bioynthesis	38.46	5 of 13
66794	ascorbate metabolism	36.36	8 of 22
66794	dolichyl-diphosphooligosaccharide biosynthesis	36.36	4 of 11
66794	acetyl CoA biosynthesis	33.33	1 of 3
66794	(5R)-carbapenem carboxylate biosynthesis	33.33	1 of 3
66794	sulfoquinovose degradation	33.33	1 of 3
66794	chlorophyll metabolism	33.33	6 of 18
66794	phenylpropanoid biosynthesis	30.77	4 of 13
66794	mevalonate metabolism	28.57	2 of 7
66794	aclacinomycin biosynthesis	28.57	2 of 7
66794	alginate biosynthesis	25	1 of 4
66794	catecholamine biosynthesis	25	1 of 4
66794	vitamin E metabolism	25	1 of 4
66794	carnitine metabolism	25	2 of 8
66794	CMP-KDO biosynthesis	25	1 of 4

API 20E

API zym

Isolation source categories

Isolation

Risk assessment

Genome sequences

@ref	Description	Assembly level	INSDC accession	BV-BRC accession	IMG accession	NCBI tax ID	Score
66792	ASM2534v1 assembly for Geodermatophilus obscurus DSM 43160	complete	GCA_000025345	526225.7	646311931	526225	98.99
124043	ASM3954479v1 assembly for Geodermatophilus obscurus DSM 43160 NBRC 13315	contig	GCA_039544795			526225	56.58

16S sequences

@ref	Description	Accession	Length	Database	NCBI tax ID
20218	Geodermatophilus obscurus DSM 43160 16S ribosomal RNA gene, partial sequence	JQ899243	646		526225
20218	G.obscurus 16S ribosomal RNA (strain DSM43160)	X92356	1482		526225
67771	Geodermatophilus obscurus obscurus 16S ribosomal RNA (16S rRNA) gene	L40620	1416		1861
124043	Geodermatophilus obscurus DSM 43160 16S ribosomal RNA gene, partial sequence.	PQ248422	601		526225

Predictions

Literature

Topic	Title	Authors	Journal	DOI	Year
Genetics	Effects of simulated space environmental conditions on cleanroom microbes.	Cassilly CD, Chander AM, Vaughn JA, Kunstman KJ, Green SJ, Venkateswaran K, Bertone PF, Bahr CW, Marcella SA, Morris HC.	Front Microbiol	10.3389/fmicb.2025.1600106	2025
Phylogeny	Biosynthetic gene clusters with biotechnological applications in novel Antarctic isolates from Actinomycetota.	Bruna P, Nunez-Montero K, Contreras MJ, Leal K, Garcia M, Abanto M, Barrientos L.	Appl Microbiol Biotechnol	10.1007/s00253-024-13154-x	2024
Genetics	Draft Genomes Sequences of 11 Geodermatophilaceae Strains Isolated from Building Stones from New England and Indian Stone Ruins found at historic sites in Tamil Nadu, India.	Ennis NJ, Dharumadurai D, Sevigny JL, Wilmot R, Alnaimat SM, Bryce JG, Thomas WK, Tisa LS.	J Genomics	10.7150/jgen.76121	2022
	Role of fourteen XRE-DUF397 pairs from Streptomyces coelicolor as regulators of antibiotic production and differentiation. New players in a complex regulatory network.	Riascos C, Martinez-Carrasco A, Diaz M, Santamaria RI.	Front Microbiol	10.3389/fmicb.2023.1217350	2023
	Isolation and characterization of multiple-stress tolerant bacteria from radon springs.	Timkina E, Kulisova M, Palyzova A, Maresova H, Matatkova O, Rezanka T, Kolouchova IJ.	PLoS One	10.1371/journal.pone.0299532	2024
Genetics	Mining of Microbial Genomes for the Novel Sources of Nitrilases.	Sharma N, Thakur N, Raj T, Savitri, Bhalla TC.	Biomed Res Int	10.1155/2017/7039245	2017
Phylogeny	Ubiquity, diversity and physiological characteristics of Geodermatophilaceae in Shapotou National Desert Ecological Reserve.	Sun HM, Zhang T, Yu LY, Sen K, Zhang YQ.	Front Microbiol	10.3389/fmicb.2015.01059	2015
	Stone-dwelling actinobacteria Blastococcus saxobsidens, Modestobacter marinus and Geodermatophilus obscurus proteogenomes.	Sghaier H, Hezbri K, Ghodhbane-Gtari F, Pujic P, Sen A, Daffonchio D, Boudabous A, Tisa LS, Klenk HP, Armengaud J, Normand P, Gtari M.	ISME J	10.1038/ismej.2015.108	2016
	Characterization of a D-lyxose isomerase from Bacillus velezensis and its application for the production of D-mannose and L-ribose.	Guo Z, Long L, Ding S.	AMB Express	10.1186/s13568-019-0877-3	2019
	Analysis of EAWAG-BBD pathway prediction system for the identification of malathion degrading microbes.	Sivakumar S, Anitha P, Ramesh B, Suresh G.	Bioinformation	10.6026/97320630013073	2017
Phylogeny	Real-time PCR for the detection and quantification of geodermatophilaceae from stone samples and identification of new members of the genus blastococcus.	Salazar O, Valverde A, Genilloud O.	Appl Environ Microbiol	10.1128/aem.72.1.346-352.2006	2006
	Candidatus Frankia Datiscae Dg1, the Actinobacterial Microsymbiont of Datisca glomerata, Expresses the Canonical nod Genes nodABC in Symbiosis with Its Host Plant.	Persson T, Battenberg K, Demina IV, Vigil-Stenman T, Vanden Heuvel B, Pujic P, Facciotti MT, Wilbanks EG, O'Brien A, Fournier P, Cruz Hernandez MA, Mendoza Herrera A, Medigue C, Normand P, Pawlowski K, Berry AM.	PLoS One	10.1371/journal.pone.0127630	2015
Genetics	Picodroplet partitioned whole genome amplification of low biomass samples preserves genomic diversity for metagenomic analysis.	Hammond M, Homa F, Andersson-Svahn H, Ettema TJ, Joensson HN.	Microbiome	10.1186/s40168-016-0197-7	2016
Phylogeny	A primary assessment of the endophytic bacterial community in a xerophilous moss (Grimmia montana) using molecular method and cultivated isolates.	Liu XL, Liu SL, Liu M, Kong BH, Liu L, Li YH.	Braz J Microbiol	10.1590/s1517-83822014000100022	2014
Metabolism	Heterologous Production of the Marine Myxobacterial Antibiotic Haliangicin and Its Unnatural Analogues Generated by Engineering of the Biochemical Pathway.	Sun Y, Feng Z, Tomura T, Suzuki A, Miyano S, Tsuge T, Mori H, Suh JW, Iizuka T, Fudou R, Ojika M.	Sci Rep	10.1038/srep22091	2016
Metabolism	The actinomycin biosynthetic gene cluster of Streptomyces chrysomallus: a genetic hall of mirrors for synthesis of a molecule with mirror symmetry.	Keller U, Lang M, Crnovcic I, Pfennig F, Schauwecker F.	J Bacteriol	10.1128/jb.01526-09	2010
	A multi-source domain annotation pipeline for quantitative metagenomic and metatranscriptomic functional profiling.	Ugarte A, Vicedomini R, Bernardes J, Carbone A.	Microbiome	10.1186/s40168-018-0532-2	2018
Pathogenicity	Tetracycline resistance and presence of tetracycline resistance determinants tet(V) and tap in rapidly growing mycobacteria from agricultural soils and clinical isolates.	Kyselkova M, Chronakova A, Volna L, Nemec J, Ulmann V, Scharfen J, Elhottova D.	Microbes Environ	10.1264/jsme2.me12028	2012
Metabolism	Defining sequence space and reaction products within the cyanuric acid hydrolase (AtzD)/barbiturase protein family.	Seffernick JL, Erickson JS, Cameron SM, Cho S, Dodge AG, Richman JE, Sadowsky MJ, Wackett LP.	J Bacteriol	10.1128/jb.00791-12	2012
Phenotype	Predicting phenotypic traits of prokaryotes from protein domain frequencies.	Lingner T, Muhlhausen S, Gabaldon T, Notredame C, Meinicke P.	BMC Bioinformatics	10.1186/1471-2105-11-481	2010
Enzymology	PKMiner: a database for exploring type II polyketide synthases.	Kim J, Yi GS.	BMC Microbiol	10.1186/1471-2180-12-169	2012
Phylogeny	Biogeography and phylogenetic diversity of a cluster of exclusively marine myxobacteria.	Brinkhoff T, Fischer D, Vollmers J, Voget S, Beardsley C, Thole S, Mussmann M, Kunze B, Wagner-Dobler I, Daniel R, Simon M.	ISME J	10.1038/ismej.2011.190	2012
	Cyanuric acid hydrolase: evolutionary innovation by structural concatenation.	Peat TS, Balotra S, Wilding M, French NG, Briggs LJ, Panjikar S, Cowieson N, Newman J, Scott C.	Mol Microbiol	10.1111/mmi.12249	2013
	Bioinformatic evidence for a widely distributed, ribosomally produced electron carrier precursor, its maturation proteins, and its nicotinoprotein redox partners.	Haft DH.	BMC Genomics	10.1186/1471-2164-12-21	2011
	Annotation of Protein Domains Reveals Remarkable Conservation in the Functional Make up of Proteomes Across Superkingdoms.	Nasir A, Naeem A, Khan MJ, Nicora HD, Caetano-Anolles G.	Genes (Basel)	10.3390/genes2040869	2011
Genetics	Developmental biology of Streptomyces from the perspective of 100 actinobacterial genome sequences.	Chandra G, Chater KF.	FEMS Microbiol Rev	10.1111/1574-6976.12047	2014
Phylogeny	Phylogenetic framework and molecular signatures for the main clades of the phylum Actinobacteria.	Gao B, Gupta RS.	Microbiol Mol Biol Rev	10.1128/mmbr.05011-11	2012
	Classifying nitrilases as aliphatic and aromatic using machine learning technique.	Sharma N, Verma R, Savitri, Bhalla TC.	3 Biotech	10.1007/s13205-018-1102-9	2018
	Comparing the similarity of different groups of bacteria to the human proteome.	Trost B, Pajon R, Jayaprakash T, Kusalik A.	PLoS One	10.1371/journal.pone.0034007	2012
Phylogeny	Geodermatophilus, a new genus of the Dermatophilaceae (Actinomycetales).	Luedemann GM.	J Bacteriol	10.1128/jb.96.5.1848-1858.1968	1968
Enzymology	Analysis of actinomycete communities by specific amplification of genes encoding 16S rRNA and gel-electrophoretic separation in denaturing gradients.	Heuer H, Krsek M, Baker P, Smalla K, Wellington EM.	Appl Environ Microbiol	10.1128/aem.63.8.3233-3241.1997	1997
	Hydroxylation of pregnenolone and dehydroepiandrosterone by zygomycete Backusella lamprospora VKM F-944: selective production of 7alpha-OH-DHEA.	Kollerov V, Shutov A, Kazantsev A, Donova M.	Appl Microbiol Biotechnol	10.1007/s00253-021-11737-6	2022
	Differential roles of deterministic and stochastic processes in structuring soil bacterial ecotypes across terrestrial ecosystems.	Riddley M, Hepp S, Hardeep F, Nayak A, Liu M, Xing X, Zhang H, Liao J.	Nat Commun	10.1038/s41467-025-57526-x	2025
Genetics	Metagenomic analysis demonstrates distinct changes in the gut microbiome of Kawasaki diseases children.	Han L, Liu X, Lan Y, Hua Y, Fan Z, Li Y.	Front Immunol	10.3389/fimmu.2024.1416185	2024
	White root rot of Bletilla striata: the pathogen, biological characterization, and fungicide screening.	Liang F, Jiang X, Liu L, Wang F, Liu F, Hu S, Tan L, Chen X, Xu Y, Xu X, Jiang L, Liu Y, Yang C.	Front Microbiol	10.3389/fmicb.2024.1374137	2024
	Testing the Luedemann hypothesis: the discovery of novel antimicrobials from slow-growing microbes from nutrient-limited environments.	Lin B, Woo S, Philbrick A, Bacsa J, Laskey E, Mehra N, Gondil VS, Mei JA, Jones G, Pavelka MS, Dziejman M, Shutter DA, Melander C, Perritt AM, Jakober R, Shen Y, Chang W-C, Quave CL, Dunman PM, Luedemann G.	mSphere	10.1128/msphere.00367-25	2025
Genetics	Whole-Genome Sequencing and Biotechnological Potential Assessment of Two Bacterial Strains Isolated from Poultry Farms in Belgorod, Russia.	Senchenkov VY, Lyakhovchenko NS, Nikishin IA, Myagkov DA, Chepurina AA, Polivtseva VN, Abashina TN, Delegan YA, Nikulicheva TB, Nikulin IS, Bogun AG, Solomentsev VI, Solyanikova IP.	Microorganisms	10.3390/microorganisms11092235	2023
	Aspects of nitrogen-fixing Actinobacteria, in particular free-living and symbiotic Frankia.	Sellstedt A, Richau KH.	FEMS Microbiol Lett	10.1111/1574-6968.12116	2013
Genetics	A comprehensive metagenomics framework to characterize organisms relevant for planetary protection.	Danko DC, Sierra MA, Benardini JN, Guan L, Wood JM, Singh N, Seuylemezian A, Butler DJ, Ryon K, Kuchin K, Meleshko D, Bhattacharya C, Venkateswaran KJ, Mason CE.	Microbiome	10.1186/s40168-021-01020-1	2021
Metabolism	Contrasted resistance of stone-dwelling Geodermatophilaceae species to stresses known to give rise to reactive oxygen species.	Gtari M, Essoussi I, Maaoui R, Sghaier H, Boujmil R, Gury J, Pujic P, Brusetti L, Chouaia B, Crotti E, Daffonchio D, Boudabous A, Normand P.	FEMS Microbiol Ecol	10.1111/j.1574-6941.2012.01320.x	2012
Genetics	Genome-Wide Pathway Exploration of the Epidermidibacterium keratini EPI-7T.	Oh Y, Mun S, Choi YB, Jo H, Lee DG, Han K.	Microorganisms	10.3390/microorganisms11040870	2023
Genetics	Multi-faceted metagenomic analysis of spacecraft associated surfaces reveal planetary protection relevant microbial composition.	Highlander SK, Wood JM, Gillece JD, Folkerts M, Fofanov V, Furstenau T, Singh NK, Guan L, Seuylemezian A, Benardini JN, Engelthaler DM, Venkateswaran K, Keim PS.	PLoS One	10.1371/journal.pone.0282428	2023
	Functionalization of MWCNTs for Bioelectrocatalysis by Bacterial Two-Domain Laccase from Catenuloplanes japonicus.	Abdullatypov A, Oskin P, Fedina V, Trubitsina L, Yakimovich S, Shuvalova E, Verma P, Dyachkova T, Ponamoreva O, Alferov S.	Nanomaterials (Basel)	10.3390/nano13233019	2023
	Comparative genomics unveils extensive genomic variation between populations of Listeria species in natural and food-associated environments.	Liao J, Guo X, Li S, Anupoju SMB, Cheng RA, Weller DL, Sullivan G, Zhang H, Deng X, Wiedmann M.	ISME Commun	10.1038/s43705-023-00293-x	2023
	Structural basis of DNA binding by the WhiB-like transcription factor WhiB3 in Mycobacterium tuberculosis.	Wan T, Horova M, Khetrapal V, Li S, Jones C, Schacht A, Sun X, Zhang L.	J Biol Chem	10.1016/j.jbc.2023.104777	2023
Genetics	Comparative Genomics Reveals the Regulatory Complexity of Bifidobacterial Arabinose and Arabino-Oligosaccharide Utilization.	Arzamasov AA, van Sinderen D, Rodionov DA.	Front Microbiol	10.3389/fmicb.2018.00776	2018
Genetics	Longitudinal Metagenomic Analysis of Hospital Air Identifies Clinically Relevant Microbes.	King P, Pham LK, Waltz S, Sphar D, Yamamoto RT, Conrad D, Taplitz R, Torriani F, Forsyth RA.	PLoS One	10.1371/journal.pone.0160124	2016
Biotechnology	Chemical Structure of Stabilizing Layers of Negatively Charged Silver Nanoparticles as an Effector of Shifts in Soil Bacterial Microbiome under Short-Term Exposure.	Przemieniecki SW, Ocwieja M, Ciesielski S, Halecki W, Matras E, Gorczyca A.	Int J Environ Res Public Health	10.3390/ijerph192114438	2022
Phylogeny	Morphological, physiological, and molecular characterization of actinomycetes isolated from dry soil, rocks, and monument surfaces.	Eppard M, Krumbein WE, Koch C, Rhiel E, Staley JT, Stackebrandt E.	Arch Microbiol	10.1007/s002030050350	1996
	Soil carbonyl sulfide exchange in relation to microbial community composition: insights from a managed grassland soil amendment experiment.	Kitz F, Gomez-Brandon M, Eder B, Etemadi M, Spielmann FM, Hammerle A, Insam H, Wohlfahrt G.	Soil Biol Biochem	10.1016/j.soilbio.2019.04.005	2019
	Airborne Bacterial Communities in Three East Asian Cities of China, South Korea, and Japan.	Lee JY, Park EH, Lee S, Ko G, Honda Y, Hashizume M, Deng F, Yi SM, Kim H.	Sci Rep	10.1038/s41598-017-05862-4	2017
Metabolism	Identification of an apiosyltransferase in the plant pathogen Xanthomonas pisi.	Smith JA, Bar-Peled M.	PLoS One	10.1371/journal.pone.0206187	2018
	Structural Conservation and Diversity of PilZ-Related Domains.	Galperin MY, Chou SH.	J Bacteriol	10.1128/jb.00664-19	2020
	Concentration and Community of Airborne Bacteria in Response to Cyclical Haze Events During the Fall and Midwinter in Beijing, China.	Li W, Yang J, Zhang D, Li B, Wang E, Yuan H.	Front Microbiol	10.3389/fmicb.2018.01741	2018
	Characterization of black patina from the Tiber River embankments using Next-Generation Sequencing.	Antonelli F, Esposito A, Calvo L, Licursi V, Tisseyre P, Ricci S, Romagnoli M, Piazza S, Guerrieri F.	PLoS One	10.1371/journal.pone.0227639	2020
	Characterization of a spontaneous thiostrepton-resistant Frankia alni infective isolate using PCR-RFLP of nif and glnII genes	Cournoyer B, Normand P.	Soil Biol Biochem	10.1016/0038-0717(94)90242-9	1994
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	Widespread abundance of functional bacterial amyloid in mycolata and other gram-positive bacteria.	Jordal PB, Dueholm MS, Larsen P, Petersen SV, Enghild JJ, Christiansen G, Hojrup P, Nielsen PH, Otzen DE.	Appl Environ Microbiol	10.1128/aem.02107-08	2009
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Phylogeny	A phylogenetic analysis of the family Dermatophilaceae.	Stackebrandt E, Kroppenstedt RM, Fowler VJ.	J Gen Microbiol	10.1099/00221287-129-6-1831	1983
Metabolism	Biocatalytic anti-Prelog reduction of prochiral ketones with whole cells of Acetobacter pasteurianus GIM1.158.	Du PX, Wei P, Lou WY, Zong MH.	Microb Cell Fact	10.1186/1475-2859-13-84	2014
	Richness and diversity in dust stormborne biomes at the southeast mediterranean.	Katra I, Arotsker L, Krasnov H, Zaritsky A, Kushmaro A, Ben-Dov E.	Sci Rep	10.1038/srep05265	2014
Phylogeny	Inhalable microorganisms in Beijing's PM2.5 and PM10 pollutants during a severe smog event.	Cao C, Jiang W, Wang B, Fang J, Lang J, Tian G, Jiang J, Zhu TF.	Environ Sci Technol	10.1021/es4048472	2014
	Disruption of Mycobacterium avium subsp. paratuberculosis-specific genes impairs in vivo fitness.	Wang J, Pritchard JR, Kreitmann L, Montpetit A, Behr MA.	BMC Genomics	10.1186/1471-2164-15-415	2014
Phylogeny	Microbial hitchhikers on intercontinental dust: catching a lift in Chad.	Favet J, Lapanje A, Giongo A, Kennedy S, Aung YY, Cattaneo A, Davis-Richardson AG, Brown CT, Kort R, Brumsack HJ, Schnetger B, Chappell A, Kroijenga J, Beck A, Schwibbert K, Mohamed AH, Kirchner T, de Quadros PD, Triplett EW, Broughton WJ, Gorbushina AA.	ISME J	10.1038/ismej.2012.152	2013
Phylogeny	Numerical classification of sporoactinomycetes containing meso-diaminopimelic acid in the cell wall.	Goodfellow M, Pirouz T.	J Gen Microbiol	10.1099/00221287-128-3-503	1982
Genetics	Elevated Rate of Genome Rearrangements in Radiation-Resistant Bacteria.	Repar J, Supek F, Klanjscek T, Warnecke T, Zahradka K, Zahradka D.	Genetics	10.1534/genetics.116.196154	2017
Genetics	Metagenomic Analysis from the Interior of a Speleothem in Tjuv-Ante's Cave, Northern Sweden.	Zepeda Mendoza ML, Lundberg J, Ivarsson M, Campos P, Nylander JA, Sallstedt T, Dalen L.	PLoS One	10.1371/journal.pone.0151577	2016
Phylogeny	Taxonomic and functional profiles of soil samples from Atlantic forest and Caatinga biomes in northeastern Brazil.	Pacchioni RG, Carvalho FM, Thompson CE, Faustino AL, Nicolini F, Pereira TS, Silva RC, Cantao ME, Gerber A, Vasconcelos AT, Agnez-Lima LF.	Microbiologyopen	10.1002/mbo3.169	2014
Genetics	Comparative genomics reveals evidence of marine adaptation in Salinispora species.	Penn K, Jensen PR.	BMC Genomics	10.1186/1471-2164-13-86	2012
Metabolism	Cyclic Di-GMP phosphodiesterases RmdA and RmdB are involved in regulating colony morphology and development in Streptomyces coelicolor.	Hull TD, Ryu MH, Sullivan MJ, Johnson RC, Klena NT, Geiger RM, Gomelsky M, Bennett JA.	J Bacteriol	10.1128/jb.00157-12	2012
Phylogeny	Differentiation of Lactobacillus plantarum, L. pentosus, and L. paraplantarum by recA gene sequence analysis and multiplex PCR assay with recA gene-derived primers.	Torriani S, Felis GE, Dellaglio F.	Appl Environ Microbiol	10.1128/aem.67.8.3450-3454.2001	2001
Metabolism	Degradation of carbonyl sulfide by Actinomycetes and detection of clade D of beta-class carbonic anhydrase.	Ogawa T, Kato H, Higashide M, Nishimiya M, Katayama Y	FEMS Microbiol Lett	10.1093/femsle/fnw223	2016
Genetics	Complete genome sequence of Geodermatophilus obscurus type strain (G-20).	Ivanova N, Sikorski J, Jando M, Munk C, Lapidus A, Glavina Del Rio T, Copeland A, Tice H, Cheng JF, Lucas S, Chen F, Nolan M, Bruce D, Goodwin L, Pitluck S, Mavromatis K, Mikhailova N, Pati A, Chen A, Palaniappan K, Land M, Hauser L, Chang YJ, Jeffries CD, Meincke L, Brettin T, Detter JC, Rohde M, Goker M, Bristow J, Eisen JA, Markowitz V, Hugenholtz P, Kyrpides NC, Klenk HP	Stand Genomic Sci	10.4056/sigs.711311	2010
Phylogeny	Geodermatophilus maliterrae sp. nov., a member of the Geodermatophilaceae isolated from badland surfaces in the Red Desert, Wyoming, USA.	Ben Tekaya S, Nouioui I, Flores GM, Neumann-Schaal M, Bredoire F, Basile F, van Diepen LTA, Ward NL.	Int J Syst Evol Microbiol	10.1099/ijsem.0.006603	2024
	Geodermatophilus poikilotrophi sp. nov.: a multitolerant actinomycete isolated from dolomitic marble.	del Carmen Montero-Calasanz M, Hofner B, Goker M, Rohde M, Sproer C, Hezbri K, Gtari M, Schumann P, Klenk HP.	Biomed Res Int	10.1155/2014/914767	2014
Phylogeny	Morphological, molecular and 3D synchrotron X-ray tomographic characterizations of Helicascus satunensis sp. nov., a novel mangrove fungus.	Preedanon S, Klaysuban A, Suetrong S, Pracharoen O, Promchoo W, Sangtiean T, Rojviriya C, Sakayaroj J.	PeerJ	10.7717/peerj.18341	2024
Phylogeny	Description of gamma radiation-resistant Geodermatophilus dictyosporus sp. nov. to accommodate the not validly named Geodermatophilus obscurus subsp. dictyosporus (Luedemann, 1968).	Montero-Calasanz Mdel C, Hezbri K, Goker M, Sghaier H, Rohde M, Sproer C, Schumann P, Klenk HP.	Extremophiles	10.1007/s00792-014-0708-z	2015
Phylogeny	Description of Geodermatophilus amargosae sp. nov., to accommodate the not validly named Geodermatophilus obscurus subsp. amargosae (Luedemann, 1968).	Montero-Calasanz Mdel C, Goker M, Rohde M, Sproer C, Schumann P, Mayilraj S, Goodfellow M, Klenk HP.	Curr Microbiol	10.1007/s00284-013-0479-2	2014
Phylogeny	Geodermatophilus siccatus sp. nov., isolated from arid sand of the Saharan desert in Chad.	del Carmen Montero-Calasanz M, Goker M, Rohde M, Schumann P, Potter G, Sproer C, Gorbushina AA, Klenk HP.	Antonie Van Leeuwenhoek	10.1007/s10482-012-9824-x	2013
Phylogeny	Blastococcus jejuensis sp. nov., an actinomycete from beach sediment, and emended description of the genus Blastococcus Ahrens and Moll 1970.	Lee SD.	Int J Syst Evol Microbiol	10.1099/ijs.0.64268-0	2006
Phylogeny	Geodermatophilus marinus sp. nov., isolated from the marine sponge Leucetta chagosensis.	Li L, Zhang D, Tang WZ, Lin HW, Lu YH	Int J Syst Evol Microbiol	10.1099/ijsem.0.003478	2019
Phylogeny	Geodermatophilus chilensis sp. nov., from soil of the Yungay core-region of the Atacama Desert, Chile.	Castro JF, Nouioui I, Sangal V, Trujillo ME, Montero-Calasanz MDC, Rahmani T, Bull AT, Asenjo JA, Andrews BA, Goodfellow M	Syst Appl Microbiol	10.1016/j.syapm.2018.03.005	2018
Phylogeny	Geodermatophilus telluris sp. nov., an actinomycete isolated from Saharan desert sand.	Montero-Calasanz MDC, Goker M, Potter G, Rohde M, Sproer C, Schumann P, Klenk HP, Gorbushina AA	Int J Syst Evol Microbiol	10.1099/ijs.0.046888-0	2012
Phylogeny	Geodermatophilus nigrescens sp. nov., isolated from a dry-hot valley.	Nie GX, Ming H, Li S, Zhou EM, Cheng J, Yu TT, Zhang J, Feng HG, Tang SK, Li WJ	Antonie Van Leeuwenhoek	10.1007/s10482-012-9696-0	2012
Phylogeny	Geodermatophilus ruber sp. nov., isolated from rhizosphere soil of a medicinal plant.	Zhang YQ, Chen J, Liu HY, Zhang YQ, Li WJ, Yu LY	Int J Syst Evol Microbiol	10.1099/ijs.0.020610-0	2010