Capnocytophaga cynodegmi 79120329 is a microaerophile, Gram-negative, rod-shaped human pathogen that was isolated from mouth of a dog.
Gram-negative rod-shaped microaerophile human pathogen genome sequence 16S sequence Bacteria| @ref 20215 |
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| Domain Bacteria |
| Phylum Bacteroidota |
| Class Flavobacteriia |
| Order Flavobacteriales |
| Family Flavobacteriaceae |
| Genus Capnocytophaga |
| Species Capnocytophaga cynodegmi |
| Full scientific name Capnocytophaga cynodegmi Brenner et al. 1990 |
| BacDive ID | Other strains from Capnocytophaga cynodegmi (5) | Type strain |
|---|---|---|
| 143538 | C. cynodegmi CCUG 19954 | |
| 146217 | C. cynodegmi CCUG 30624, MCCM 00262, LMG 11538 | |
| 146218 | C. cynodegmi CCUG 30625, MCCM 00263, LMG 11539 | |
| 149924 | C. cynodegmi CCUG 38690 | |
| 154589 | C. cynodegmi CCUG 54501 |
| 8133 | Incubation period2-3 days |
| @ref: | 66793 |
| multimedia content: | EM_DSM_19736_1.jpg |
| multimedia.multimedia content: | EM_DSM_19736_1.jpg |
| caption: | electron microscopic image |
| intellectual property rights: | © HZI/Manfred Rohde |
| manual_annotation: | 1 |
| @ref | Name | Growth | Medium link | Composition | |
|---|---|---|---|---|---|
| 8133 | COLUMBIA BLOOD MEDIUM (DSMZ Medium 693) | Medium recipe at MediaDive | Name: COLUMBIA BLOOD MEDIUM (DSMZ Medium 693) Composition: Defibrinated sheep blood 50.0 g/l Columbia agar base | ||
| 34432 | MEDIUM 10 - Chocolate medium for Actinobacillus pleuropneumoniae, Capnocytophaga cynodegmi, Haemophilus and Neisseria | Distilled water make up to (1000.000 ml);Columbia agar (39.000 g);Horseblood (100.000 ml);PolyVitex mischung (10.000 ml) | |||
| 118831 | CIP Medium 10 | Medium recipe at CIP |
| @ref | Chebi-ID | Metabolite | Utilization activity | Kind of utilization tested | |
|---|---|---|---|---|---|
| 118831 | 16947 ChEBI | citrate | - | carbon source | |
| 118831 | 15824 ChEBI | D-fructose | + | degradation | |
| 118831 | 17634 ChEBI | D-glucose | - | degradation | |
| 118831 | 4853 ChEBI | esculin | + | hydrolysis | |
| 118831 | 606565 ChEBI | hippurate | - | hydrolysis | |
| 118831 | 17632 ChEBI | nitrate | - | reduction | |
| 118831 | 16301 ChEBI | nitrite | - | reduction |
| @ref | Value | Activity | Ec | |
|---|---|---|---|---|
| 68382 | acid phosphatase | + | 3.1.3.2 | from API zym |
| 118831 | alcohol dehydrogenase | + | 1.1.1.1 | |
| 68382 | alkaline phosphatase | + | 3.1.3.1 | from API zym |
| 68382 | alpha-chymotrypsin | - | 3.4.21.1 | from API zym |
| 68382 | alpha-fucosidase | - | 3.2.1.51 | from API zym |
| 68382 | alpha-galactosidase | - | 3.2.1.22 | from API zym |
| 68382 | alpha-glucosidase | + | 3.2.1.20 | from API zym |
| 68382 | alpha-mannosidase | - | 3.2.1.24 | from API zym |
| 68382 | beta-galactosidase | - | 3.2.1.23 | from API zym |
| 118831 | beta-galactosidase | + | 3.2.1.23 | |
| 68382 | beta-glucosidase | - | 3.2.1.21 | from API zym |
| 68382 | beta-glucuronidase | - | 3.2.1.31 | from API zym |
| 118831 | catalase | + | 1.11.1.6 | |
| 68382 | cystine arylamidase | - | 3.4.11.3 | from API zym |
| 68382 | esterase (C 4) | + | from API zym | |
| 68382 | esterase lipase (C 8) | + | from API zym | |
| 118831 | gamma-glutamyltransferase | - | 2.3.2.2 | |
| 118831 | gelatinase | - | ||
| 68382 | leucine arylamidase | + | 3.4.11.1 | from API zym |
| 68382 | lipase (C 14) | - | from API zym | |
| 118831 | lysine decarboxylase | - | 4.1.1.18 | |
| 68382 | N-acetyl-beta-glucosaminidase | + | 3.2.1.52 | from API zym |
| 68382 | naphthol-AS-BI-phosphohydrolase | + | from API zym | |
| 118831 | ornithine decarboxylase | - | 4.1.1.17 | |
| 118831 | oxidase | + | ||
| 118831 | phenylalanine ammonia-lyase | - | 4.3.1.24 | |
| 68382 | trypsin | - | 3.4.21.4 | from API zym |
| 118831 | urease | - | 3.5.1.5 | |
| 68382 | valine arylamidase | - | from API zym |
| @ref | pathway | enzyme coverage | annotated reactions | external links | |
|---|---|---|---|---|---|
| 66794 | coenzyme A metabolism | 100 | 4 of 4 | ||
| 66794 | ppGpp biosynthesis | 100 | 4 of 4 | ||
| 66794 | vitamin K metabolism | 100 | 5 of 5 | ||
| 66794 | gluconeogenesis | 100 | 8 of 8 | ||
| 66794 | palmitate biosynthesis | 100 | 22 of 22 | ||
| 66794 | sulfopterin metabolism | 100 | 4 of 4 | ||
| 66794 | CDP-diacylglycerol biosynthesis | 100 | 2 of 2 | ||
| 66794 | UDP-GlcNAc biosynthesis | 100 | 3 of 3 | ||
| 66794 | suberin monomers biosynthesis | 100 | 2 of 2 | ||
| 66794 | anapleurotic synthesis of oxalacetate | 100 | 1 of 1 | ||
| 66794 | folate polyglutamylation | 100 | 1 of 1 | ||
| 66794 | adipate degradation | 100 | 2 of 2 | ||
| 66794 | biotin biosynthesis | 100 | 4 of 4 | ||
| 66794 | cis-vaccenate biosynthesis | 100 | 2 of 2 | ||
| 66794 | starch degradation | 90 | 9 of 10 | ||
| 66794 | chorismate metabolism | 88.89 | 8 of 9 | ||
| 66794 | C4 and CAM-carbon fixation | 87.5 | 7 of 8 | ||
| 66794 | photosynthesis | 85.71 | 12 of 14 | ||
| 66794 | glycogen metabolism | 80 | 4 of 5 | ||
| 66794 | cellulose degradation | 80 | 4 of 5 | ||
| 66794 | peptidoglycan biosynthesis | 80 | 12 of 15 | ||
| 66794 | tetrahydrofolate metabolism | 78.57 | 11 of 14 | ||
| 66794 | CO2 fixation in Crenarchaeota | 77.78 | 7 of 9 | ||
| 66794 | lipid A biosynthesis | 77.78 | 7 of 9 | ||
| 66794 | acetate fermentation | 75 | 3 of 4 | ||
| 66794 | glycogen biosynthesis | 75 | 3 of 4 | ||
| 66794 | CMP-KDO biosynthesis | 75 | 3 of 4 | ||
| 66794 | NAD metabolism | 72.22 | 13 of 18 | ||
| 66794 | heme metabolism | 71.43 | 10 of 14 | ||
| 66794 | purine metabolism | 69.15 | 65 of 94 | ||
| 66794 | serine metabolism | 66.67 | 6 of 9 | ||
| 66794 | aspartate and asparagine metabolism | 66.67 | 6 of 9 | ||
| 66794 | d-mannose degradation | 66.67 | 6 of 9 | ||
| 66794 | acetoin degradation | 66.67 | 2 of 3 | ||
| 66794 | cyanate degradation | 66.67 | 2 of 3 | ||
| 66794 | flavin biosynthesis | 66.67 | 10 of 15 | ||
| 66794 | pyrimidine metabolism | 66.67 | 30 of 45 | ||
| 66794 | vitamin B6 metabolism | 63.64 | 7 of 11 | ||
| 66794 | 6-hydroxymethyl-dihydropterin diphosphate biosynthesis | 62.5 | 5 of 8 | ||
| 66794 | Entner Doudoroff pathway | 60 | 6 of 10 | ||
| 66794 | propionate fermentation | 60 | 6 of 10 | ||
| 66794 | metabolism of amino sugars and derivatives | 60 | 3 of 5 | ||
| 66794 | threonine metabolism | 60 | 6 of 10 | ||
| 66794 | glycolysis | 58.82 | 10 of 17 | ||
| 66794 | citric acid cycle | 57.14 | 8 of 14 | ||
| 66794 | ubiquinone biosynthesis | 57.14 | 4 of 7 | ||
| 66794 | degradation of hexoses | 55.56 | 10 of 18 | ||
| 66794 | lipid metabolism | 54.84 | 17 of 31 | ||
| 66794 | glutamate and glutamine metabolism | 53.57 | 15 of 28 | ||
| 66794 | non-pathway related | 52.63 | 20 of 38 | ||
| 66794 | alanine metabolism | 51.72 | 15 of 29 | ||
| 66794 | dTDPLrhamnose biosynthesis | 50 | 4 of 8 | ||
| 66794 | cysteine metabolism | 50 | 9 of 18 | ||
| 66794 | ethanol fermentation | 50 | 1 of 2 | ||
| 66794 | butanoate fermentation | 50 | 2 of 4 | ||
| 66794 | isoleucine metabolism | 50 | 4 of 8 | ||
| 66794 | kanosamine biosynthesis II | 50 | 1 of 2 | ||
| 66794 | dolichol and dolichyl phosphate biosynthesis | 50 | 1 of 2 | ||
| 66794 | oxidative phosphorylation | 48.35 | 44 of 91 | ||
| 66794 | phenylalanine metabolism | 46.15 | 6 of 13 | ||
| 66794 | pentose phosphate pathway | 45.45 | 5 of 11 | ||
| 66794 | degradation of sugar acids | 44 | 11 of 25 | ||
| 66794 | cardiolipin biosynthesis | 42.86 | 3 of 7 | ||
| 66794 | tyrosine metabolism | 42.86 | 6 of 14 | ||
| 66794 | isoprenoid biosynthesis | 42.31 | 11 of 26 | ||
| 66794 | degradation of aromatic, nitrogen containing compounds | 41.67 | 5 of 12 | ||
| 66794 | lysine metabolism | 40.48 | 17 of 42 | ||
| 66794 | lipoate biosynthesis | 40 | 2 of 5 | ||
| 66794 | O-antigen biosynthesis | 40 | 2 of 5 | ||
| 66794 | arachidonate biosynthesis | 40 | 2 of 5 | ||
| 66794 | degradation of pentoses | 39.29 | 11 of 28 | ||
| 66794 | sulfate reduction | 38.46 | 5 of 13 | ||
| 66794 | leucine metabolism | 38.46 | 5 of 13 | ||
| 66794 | vitamin B1 metabolism | 38.46 | 5 of 13 | ||
| 66794 | ketogluconate metabolism | 37.5 | 3 of 8 | ||
| 66794 | tryptophan metabolism | 36.84 | 14 of 38 | ||
| 66794 | metabolism of disaccharids | 36.36 | 4 of 11 | ||
| 66794 | proline metabolism | 36.36 | 4 of 11 | ||
| 66794 | glycolate and glyoxylate degradation | 33.33 | 2 of 6 | ||
| 66794 | pantothenate biosynthesis | 33.33 | 2 of 6 | ||
| 66794 | L-lactaldehyde degradation | 33.33 | 1 of 3 | ||
| 66794 | enterobactin biosynthesis | 33.33 | 1 of 3 | ||
| 66794 | (5R)-carbapenem carboxylate biosynthesis | 33.33 | 1 of 3 | ||
| 66794 | octane oxidation | 33.33 | 1 of 3 | ||
| 66794 | selenocysteine biosynthesis | 33.33 | 2 of 6 | ||
| 66794 | acetyl CoA biosynthesis | 33.33 | 1 of 3 | ||
| 66794 | IAA biosynthesis | 33.33 | 1 of 3 | ||
| 66794 | formaldehyde oxidation | 33.33 | 1 of 3 | ||
| 66794 | nitrate assimilation | 33.33 | 3 of 9 | ||
| 66794 | degradation of sugar alcohols | 31.25 | 5 of 16 | ||
| 66794 | methionine metabolism | 30.77 | 8 of 26 | ||
| 66794 | polyamine pathway | 30.43 | 7 of 23 | ||
| 66794 | coenzyme M biosynthesis | 30 | 3 of 10 | ||
| 66794 | glycine metabolism | 30 | 3 of 10 | ||
| 66794 | myo-inositol biosynthesis | 30 | 3 of 10 | ||
| 66794 | propanol degradation | 28.57 | 2 of 7 | ||
| 66794 | mevalonate metabolism | 28.57 | 2 of 7 | ||
| 66794 | reductive acetyl coenzyme A pathway | 28.57 | 2 of 7 | ||
| 66794 | histidine metabolism | 27.59 | 8 of 29 | ||
| 66794 | d-xylose degradation | 27.27 | 3 of 11 | ||
| 66794 | cyclohexanol degradation | 25 | 1 of 4 | ||
| 66794 | alginate biosynthesis | 25 | 1 of 4 | ||
| 66794 | arginine metabolism | 25 | 6 of 24 | ||
| 66794 | toluene degradation | 25 | 1 of 4 | ||
| 66794 | androgen and estrogen metabolism | 25 | 4 of 16 | ||
| 66794 | lactate fermentation | 25 | 1 of 4 | ||
| 66794 | urea cycle | 23.08 | 3 of 13 | ||
| 66794 | phenylpropanoid biosynthesis | 23.08 | 3 of 13 | ||
| 66794 | ascorbate metabolism | 22.73 | 5 of 22 | ||
| 66794 | valine metabolism | 22.22 | 2 of 9 | ||
| 66794 | arachidonic acid metabolism | 22.22 | 4 of 18 | ||
| 66794 | glutathione metabolism | 21.43 | 3 of 14 |
| Metadata FA analysis | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| type of FA analysis | whole cell analysis | |||||||||||||||||||||||||||||||||||||||||||||||||||
| method/protocol | CCUG | |||||||||||||||||||||||||||||||||||||||||||||||||||
| @ref | 48031 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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| Metadata FA analysis | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| type of FA analysis | whole cell analysis | |||||||||||||||||||||||||||||||||||||||||||||||||||
| method/protocol | CCUG | |||||||||||||||||||||||||||||||||||||||||||||||||||
| @ref | 48031 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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| Cat1 | Cat2 | Cat3 | |
|---|---|---|---|
| #Host | #Mammals | #Canidae (Dog) | |
| #Host Body-Site | #Oral cavity and airways | #Mouth |
Global distribution of 16S sequence X97245 (>99% sequence identity) for Capnocytophaga cynodegmi from Microbeatlas ![]()
| @ref | Description | Assembly level | INSDC accession | BV-BRC accession | IMG accession | NCBI tax ID | Score | |
|---|---|---|---|---|---|---|---|---|
| 66792 | ASM37918v1 assembly for Capnocytophaga cynodegmi DSM 19736 E6447 | scaffold | 926551 | 71.98 | ||||
| 66792 | Ccyn49044.1 assembly for Capnocytophaga cynodegmi Ccyn_ATCC49044 | contig | 28189 | 57.47 |
| @ref | Description | Accession | Length | Database | NCBI tax ID | |
|---|---|---|---|---|---|---|
| 20218 | Capnocytophaga cynodegmi strain CIP 103937 16S ribosomal RNA gene, partial sequence | AY643076 | 1438 | 926551 | ||
| 20218 | Capnocytophaga cynodegmi 16S ribosomal RNA | L14638 | 1463 | 28189 | ||
| 20218 | C.cynodegmi 16S rRNA gene | X97245 | 1427 | 28189 | ||
| 8133 | Capnocytophaga cynodegmi strain CIP 103937 16S ribosomal RNA gene, partial sequence; 16S-23S ribosomal RNA intergenic spacer, complete sequence; and 23S ribosomal RNA gene, partial sequence | AY661854 | 3547 | 926551 |
| 8133 | GC-content (mol%)34 |
| @ref | Trait | Model | Prediction | Confidence in % | In training data |
|---|---|---|---|---|---|
| 125439 | oxygen_tolerance | BacteriaNetⓘ | obligate aerobe | 92.88 | no |
| 125439 | gram_stain | BacteriaNetⓘ | negative | 99.31 | no |
| 125439 | motility | BacteriaNetⓘ | no | 77.05 | no |
| 125439 | spore_formation | BacteriaNetⓘ | no | 99.76 | no |
| @ref | Trait | Model | Prediction | Confidence in % | In training data |
|---|---|---|---|---|---|
| 125438 | gram-positive | gram-positiveⓘ | no | 96.44 | no |
| 125438 | anaerobic | anaerobicⓘ | no | 89.70 | yes |
| 125438 | aerobic | aerobicⓘ | no | 68.66 | yes |
| 125438 | spore-forming | spore-formingⓘ | no | 91.60 | no |
| 125438 | thermophilic | thermophileⓘ | no | 96.20 | yes |
| 125438 | flagellated | motile2+ⓘ | no | 91.48 | no |
| Topic | Title | Authors | Journal | DOI | Year | |
|---|---|---|---|---|---|---|
| Phylogeny | Capnocytophaga cynodegmi bacteremia associated with a cat bite in a patient with systemic lupus erythematosus on hemodialysis: A case report. | Nakao M, Hosokawa N, Ziren W, Yamamoto T, Ebisu Y, Watanabe N, Watari T, Otsuka Y, Osawa R. | IDCases | 10.1016/j.idcr.2025.e02240 | 2025 | |
| LolA and LolB are conserved in Bacteroidota and are crucial for gliding motility and Type IX secretion. | De Smet T, Baland E, Giovannercole F, Mignon J, Lizen L, Dugauquier R, Lauber F, Dieu M, Lima-Mendez G, Michaux C, Devos D, Renzi F. | Commun Biol | 10.1038/s42003-025-07817-2 | 2025 | ||
| Phylogeny | Molecular diversity of rumen bacterial communities from tannin-rich and fiber-rich forage fed domestic Sika deer (Cervus nippon) in China. | Li ZP, Liu HL, Li GY, Bao K, Wang KY, Xu C, Yang YF, Yang FH, Wright AD. | BMC Microbiol | 10.1186/1471-2180-13-151 | 2013 | |
| Phylogeny | Occurrence and molecular characteristics of methicillin-resistant Staphylococcus aureus and methicillin-resistant Staphylococcus pseudintermedius in an academic veterinary hospital. | Ishihara K, Shimokubo N, Sakagami A, Ueno H, Muramatsu Y, Kadosawa T, Yanagisawa C, Hanaki H, Nakajima C, Suzuki Y, Tamura Y. | Appl Environ Microbiol | 10.1128/aem.02780-09 | 2010 | |
| The application of rumen simulation technique (RUSITEC) for studying dynamics of the bacterial community and metabolome in rumen fluid and the effects of a challenge with Clostridium perfringens. | Wetzels SU, Eger M, Burmester M, Kreienbrock L, Abdulmawjood A, Pinior B, Wagner M, Breves G, Mann E. | PLoS One | 10.1371/journal.pone.0192256 | 2018 | ||
| Phylogeny | Identification of Virulent Capnocytophaga canimorsus Isolates by Capsular Typing. | Hess E, Renzi F, Koudad D, Dol M, Cornelis GR. | J Clin Microbiol | 10.1128/jcm.00249-17 | 2017 | |
| Phylogeny | Only a subset of C. canimorsus strains is dangerous for humans. | Renzi F, Dol M, Raymackers A, Manfredi P, Cornelis GR. | Emerg Microbes Infect | 10.1038/emi.2015.48 | 2015 | |
| Genetic tools for studying Capnocytophaga canimorsus. | Mally M, Cornelis GR. | Appl Environ Microbiol | 10.1128/aem.01218-08 | 2008 | ||
| Intracellular multiplication and toxic destruction of cultured macrophages by Capnocytophaga canimorsus. | Fischer LJ, Weyant RS, White EH, Quinn FD. | Infect Immun | 10.1128/iai.63.9.3484-3490.1995 | 1995 | ||
| Phylogeny | Molecular characterization of Capnocytophaga canimorsus and other canine Capnocytophaga spp. and assessment by PCR of their frequencies in dogs. | van Dam AP, van Weert A, Harmanus C, Hovius KE, Claas EC, Reubsaet FA. | J Clin Microbiol | 10.1128/jcm.01246-09 | 2009 | |
| Phylogeny | Characterization of three strains of Capnocytophaga canis isolated from patients with sepsis. | Suzuki M, Imaoka K, Haga Y, Mohri M, Nogami A, Shimojima Y, Irie Y, Sugimura S, Morikawa S | Microbiol Immunol | 10.1111/1348-0421.12642 | 2018 | |
| Enzymology | Capnocytophaga canimorsus sp. nov. (formerly CDC group DF-2), a cause of septicemia following dog bite, and C. cynodegmi sp. nov., a cause of localized wound infection following dog bite. | Brenner DJ, Hollis DG, Fanning GR, Weaver RE. | J Clin Microbiol | 10.1128/jcm.27.2.231-235.1989 | 1989 |
| #8133 | Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 19736 |
| #20215 | Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 ) |
| #20218 | Verslyppe, B., De Smet, W., De Baets, B., De Vos, P., Dawyndt P.: StrainInfo introduces electronic passports for microorganisms.. Syst Appl Microbiol. 37: 42 - 50 2014 ( DOI 10.1016/j.syapm.2013.11.002 , PubMed 24321274 ) |
| #34432 | ; Curators of the CIP; |
| #48031 | Culture Collection University of Gothenburg (CCUG) ; Curators of the CCUG; CCUG 24742 |
| #66792 | Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) . |
| #66793 | Mukherjee et al.: GEBA: 1,003 reference genomes of bacterial and archaeal isolates expand coverage of the tree of life. 35: 676 - 683 2017 ( DOI 10.1038/nbt.3886 , PubMed 28604660 ) |
| #66794 | Antje Chang, Lisa Jeske, Sandra Ulbrich, Julia Hofmann, Julia Koblitz, Ida Schomburg, Meina Neumann-Schaal, Dieter Jahn, Dietmar Schomburg: BRENDA, the ELIXIR core data resource in 2021: new developments and updates. Nucleic Acids Res. 49: D498 - D508 2020 ( DOI 10.1093/nar/gkaa1025 , PubMed 33211880 ) |
| #68382 | Automatically annotated from API zym . |
| #69479 | João F Matias Rodrigues, Janko Tackmann,Gregor Rot, Thomas SB Schmidt, Lukas Malfertheiner, Mihai Danaila,Marija Dmitrijeva, Daniela Gaio, Nicolas Näpflin and Christian von Mering. University of Zurich.: MicrobeAtlas 1.0 beta . |
| #118831 | Collection of Institut Pasteur ; Curators of the CIP; CIP 103937 |
| #125438 | Julia Koblitz, Lorenz Christian Reimer, Rüdiger Pukall, Jörg Overmann: Predicting bacterial phenotypic traits through improved machine learning using high-quality, curated datasets. 2024 ( DOI 10.1101/2024.08.12.607695 ) |
| #125439 | Philipp Münch, René Mreches, Martin Binder, Hüseyin Anil Gündüz, Xiao-Yin To, Alice McHardy: deepG: Deep Learning for Genome Sequence Data. R package version 0.3.1 . |
| #126262 | A. Lissin, I. Schober, J. F. Witte, H. Lüken, A. Podstawka, J. Koblitz, B. Bunk, P. Dawyndt, P. Vandamme, P. de Vos, J. Overmann, L. C. Reimer: StrainInfo—the central database for linked microbial strain identifiers. ( DOI 10.1093/database/baaf059 ) |
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