Brachybacterium faecium (DSM 4810, ATCC 43885, IMET 11352)

Cell morphology

Colony morphology

Multicellular morphology

Multimedia

• @ref:	66793
  multimedia content:	EM_DSM_4810_1.jpg
  multimedia.multimedia content:	EM_DSM_4810_1.jpg
  caption:	electron microscopic image
  intellectual property rights:	© HZI/Manfred Rohde
  manual_annotation:	1

Culture medium

@ref	Name	Growth	Medium link	Composition
1836	TRYPTICASE SOY YEAST EXTRACT MEDIUM (DSMZ Medium 92)		Medium recipe at MediaDive	Name: TRYPTICASE SOY YEAST EXTRACT MEDIUM (DSMZ Medium 92) Composition: Trypticase soy broth 30.0 g/l Agar 15.0 g/l Yeast extract 3.0 g/l Distilled water
20197	ISP 2			Name: ISP 2 / Yeast Malt Agar (5265); 5265 Composition Malt extract 10.0 g/l Yeast extract 4.0 g/l Glucose 4.0 g/l Agar 15.0 g/l Preparation: Sterilisation: 20 minutes at 121°C pH before sterilisation: 7.0 Usage: Maintenance and Taxonomy Organisms: All Actinomycetes
20197	ISP 4			Name: ISP 4; DSM 547 Solution I: Difco soluble starch, 10.0 g. Make a paste of the starch with a small amount of cold distilled water and bring to a volume of 500 ml. Solution II: CaCO3 2.0 g K2HPO4 (anhydrous) 1.0 g MgSO4 x 7 H2O 1.0 g NaCl 1.0 g (NH4)2SO4 2.0 g Distilled water 500.0 ml Trace salt solution (see below) 1.0 ml The pH should be between 7.0 and 7.4. Do not adjust if it is within this range. Mix solutions I and II together. Add 20.0 g agar. Liquify agar by steaming at 100°C for 10 to 20 min. Trace element solution: FeSO4 x 7 H2O 0.1 g MnCl2 x 4 H2O 0.1 g ZnSO4 x 7 H2O 0.1 g Distilled water 100.0 ml
20197	ISP 5			Name: ISP 5 (5323) Composition L-Asparagine 1.0 g/l Glycerol 10.0 g/l K2HPO4 1.0 g/l Salt solution (see preparation) 1.0 ml/l Agar 20.0 g/l Preparation: Salt solution 1.0 g FeSO4 x 7 H2O 1.0 g MnCl2 x 4 H2O 1.0 g ZNSO4 x 7 H2O in 100 ml water Sterilisation: 20 minutes at 121°C pH before sterilisation: 7.2 Usage: Maintenance and taxonomy Organisms: All Actinomycetes
40603	MEDIUM 3 - Columbia agar			Columbia agar (39.000 g);distilled water (1000.000 ml)
119224	CIP Medium 3		Medium recipe at CIP

Culture temp

Oxygen tolerance

Halophily

Murein

Observation

Metabolite utilization

@ref	Chebi-ID	Metabolite	Utilization activity	Kind of utilization tested
20197	22599 ChEBI	arabinose	+
68368	29016 ChEBI	arginine	-	hydrolysis	from API 20E
20197	62968 ChEBI	cellulose	+
68368	16947 ChEBI	citrate	-	assimilation	from API 20E
68379	17634 ChEBI	D-glucose	+	fermentation	from API Coryne
68379	16988 ChEBI	D-ribose	+	fermentation	from API Coryne
68379	65327 ChEBI	D-xylose	-	fermentation	from API Coryne
68379	4853 ChEBI	esculin	-	hydrolysis	from API Coryne
20197	28757 ChEBI	fructose	+/-
68368	5291 ChEBI	gelatin	-	hydrolysis	from API 20E
20197	17234 ChEBI	glucose	+
68379	28087 ChEBI	glycogen	-	fermentation	from API Coryne
68379	17716 ChEBI	lactose	+	fermentation	from API Coryne
68368	25094 ChEBI	lysine	-	degradation	from API 20E
68379	17306 ChEBI	maltose	-	fermentation	from API Coryne
20197	29864 ChEBI	mannitol	+/-
20197	17268 ChEBI	myo-inositol	+
68368	18257 ChEBI	ornithine	-	degradation	from API 20E
20197	16634 ChEBI	raffinose	+
20197	26546 ChEBI	rhamnose	+
20197	17992 ChEBI	sucrose	+
68379	17992 ChEBI	sucrose	+	fermentation	from API Coryne
68368	27897 ChEBI	tryptophan	-	energy source	from API 20E
68379	16199 ChEBI	urea	-	hydrolysis	from API Coryne
68368	16199 ChEBI	urea	-	hydrolysis	from API 20E
20197	18222 ChEBI	xylose	+

Metabolite production

@ref	Chebi-ID	Metabolite	Production
68368	15688 ChEBI	acetoin		from API 20E
68368	16136 ChEBI	hydrogen sulfide		from API 20E
68368	35581 ChEBI	indole		from API 20E

Metabolite tests

@ref	Chebi-ID	Metabolite	Voges-proskauer-test	Indole test
68368	15688 ChEBI	acetoin	-		from API 20E
68368	35581 ChEBI	indole		-	from API 20E

Enzymes

@ref	Value	Activity	Ec
68382	acid phosphatase	-	3.1.3.2	from API zym
68382	alkaline phosphatase	+	3.1.3.1	from API zym
68379	alkaline phosphatase	-	3.1.3.1	from API Coryne
68382	alpha-chymotrypsin	-	3.4.21.1	from API zym
68382	alpha-fucosidase	-	3.2.1.51	from API zym
68382	alpha-galactosidase	+	3.2.1.22	from API zym
68382	alpha-glucosidase	+	3.2.1.20	from API zym
68379	alpha-glucosidase	+	3.2.1.20	from API Coryne
68382	alpha-mannosidase	+	3.2.1.24	from API zym
68368	arginine dihydrolase	-	3.5.3.6	from API 20E
68382	beta-galactosidase	+	3.2.1.23	from API zym
68379	beta-galactosidase	+	3.2.1.23	from API Coryne
68368	beta-galactosidase	+	3.2.1.23	from API 20E
68382	beta-glucosidase	-	3.2.1.21	from API zym
68379	beta-glucosidase	-	3.2.1.21	from API Coryne
68382	beta-glucuronidase	-	3.2.1.31	from API zym
68379	beta-glucuronidase	+	3.2.1.31	from API Coryne
68382	cystine arylamidase	+	3.4.11.3	from API zym
68382	esterase (C 4)	+		from API zym
68382	esterase lipase (C 8)	+		from API zym
68368	gelatinase	-		from API 20E
68382	leucine arylamidase	+	3.4.11.1	from API zym
68382	lipase (C 14)	-		from API zym
68368	lysine decarboxylase	-	4.1.1.18	from API 20E
68382	N-acetyl-beta-glucosaminidase	+	3.2.1.52	from API zym
68379	N-acetyl-beta-glucosaminidase	-	3.2.1.52	from API Coryne
68382	naphthol-AS-BI-phosphohydrolase	+		from API zym
68368	ornithine decarboxylase	-	4.1.1.17	from API 20E
68379	pyrazinamidase	+	3.5.1.B15	from API Coryne
68379	pyrrolidonyl arylamidase	+	3.4.19.3	from API Coryne
68382	trypsin	-	3.4.21.4	from API zym
68368	tryptophan deaminase	-	4.1.99.1	from API 20E
68379	urease	-	3.5.1.5	from API Coryne
68368	urease	-	3.5.1.5	from API 20E
68382	valine arylamidase	+		from API zym

Pathway annotation

Computationally determined by

@ref	pathway	enzyme coverage	annotated reactions	external links
66794	adipate degradation	100	2 of 2
66794	cis-vaccenate biosynthesis	100	2 of 2
66794	starch degradation	100	10 of 10
66794	threonine metabolism	100	10 of 10
66794	aspartate and asparagine metabolism	100	9 of 9
66794	acetate fermentation	100	4 of 4
66794	glycogen metabolism	100	5 of 5
66794	palmitate biosynthesis	100	22 of 22
66794	ppGpp biosynthesis	100	4 of 4
66794	valine metabolism	100	9 of 9
66794	lipoate biosynthesis	100	5 of 5
66794	methylglyoxal degradation	100	5 of 5
66794	formaldehyde oxidation	100	3 of 3
66794	glycolate and glyoxylate degradation	100	6 of 6
66794	UDP-GlcNAc biosynthesis	100	3 of 3
66794	denitrification	100	2 of 2
66794	folate polyglutamylation	100	1 of 1
66794	CDP-diacylglycerol biosynthesis	100	2 of 2
66794	teichoic acid biosynthesis	100	1 of 1
66794	coenzyme A metabolism	100	4 of 4
66794	suberin monomers biosynthesis	100	2 of 2
66794	vitamin K metabolism	100	5 of 5
66794	anapleurotic synthesis of oxalacetate	100	1 of 1
66794	lactate fermentation	100	4 of 4
66794	Entner Doudoroff pathway	90	9 of 10
66794	serine metabolism	88.89	8 of 9
66794	chorismate metabolism	88.89	8 of 9
66794	isoleucine metabolism	87.5	7 of 8
66794	ketogluconate metabolism	87.5	7 of 8
66794	photosynthesis	85.71	12 of 14
66794	heme metabolism	85.71	12 of 14
66794	NAD metabolism	83.33	15 of 18
66794	proline metabolism	81.82	9 of 11
66794	metabolism of disaccharids	81.82	9 of 11
66794	pentose phosphate pathway	81.82	9 of 11
66794	ethylmalonyl-CoA pathway	80	4 of 5
66794	cellulose degradation	80	4 of 5
66794	flavin biosynthesis	80	12 of 15
66794	metabolism of amino sugars and derivatives	80	4 of 5
66794	degradation of sugar acids	80	20 of 25
66794	peptidoglycan biosynthesis	80	12 of 15
66794	CO2 fixation in Crenarchaeota	77.78	7 of 9
66794	d-mannose degradation	77.78	7 of 9
66794	pyrimidine metabolism	77.78	35 of 45
66794	phenylalanine metabolism	76.92	10 of 13
66794	vitamin B1 metabolism	76.92	10 of 13
66794	leucine metabolism	76.92	10 of 13
66794	purine metabolism	76.6	72 of 94
66794	6-hydroxymethyl-dihydropterin diphosphate biosynthesis	75	6 of 8
66794	sulfopterin metabolism	75	3 of 4
66794	gluconeogenesis	75	6 of 8
66794	glycogen biosynthesis	75	3 of 4
66794	dTDPLrhamnose biosynthesis	75	6 of 8
66794	C4 and CAM-carbon fixation	75	6 of 8
66794	d-xylose degradation	72.73	8 of 11
66794	alanine metabolism	72.41	21 of 29
66794	cardiolipin biosynthesis	71.43	5 of 7
66794	reductive acetyl coenzyme A pathway	71.43	5 of 7
66794	glycolysis	70.59	12 of 17
66794	histidine metabolism	68.97	20 of 29
66794	degradation of sugar alcohols	68.75	11 of 16
66794	octane oxidation	66.67	2 of 3
66794	enterobactin biosynthesis	66.67	2 of 3
66794	methane metabolism	66.67	2 of 3
66794	allantoin degradation	66.67	6 of 9
66794	L-lactaldehyde degradation	66.67	2 of 3
66794	selenocysteine biosynthesis	66.67	4 of 6
66794	acetoin degradation	66.67	2 of 3
66794	acetyl CoA biosynthesis	66.67	2 of 3
66794	molybdenum cofactor biosynthesis	66.67	6 of 9
66794	isoprenoid biosynthesis	65.38	17 of 26
66794	methionine metabolism	65.38	17 of 26
66794	citric acid cycle	64.29	9 of 14
66794	glutamate and glutamine metabolism	64.29	18 of 28
66794	degradation of pentoses	64.29	18 of 28
66794	tetrahydrofolate metabolism	64.29	9 of 14
66794	oxidative phosphorylation	63.74	58 of 91
66794	degradation of hexoses	61.11	11 of 18
66794	factor 420 biosynthesis	60	3 of 5
66794	propionate fermentation	60	6 of 10
66794	phenylacetate degradation (aerobic)	60	3 of 5
66794	lipid metabolism	58.06	18 of 31
66794	non-pathway related	57.89	22 of 38
66794	tryptophan metabolism	57.89	22 of 38
66794	glutathione metabolism	57.14	8 of 14
66794	propanol degradation	57.14	4 of 7
66794	ubiquinone biosynthesis	57.14	4 of 7
66794	cysteine metabolism	55.56	10 of 18
66794	lysine metabolism	54.76	23 of 42
66794	ascorbate metabolism	54.55	12 of 22
66794	arginine metabolism	54.17	13 of 24
66794	urea cycle	53.85	7 of 13
66794	pantothenate biosynthesis	50	3 of 6
66794	kanosamine biosynthesis II	50	1 of 2
66794	mannosylglycerate biosynthesis	50	1 of 2
66794	cyclohexanol degradation	50	2 of 4
66794	tyrosine metabolism	50	7 of 14
66794	quinate degradation	50	1 of 2
66794	ethanol fermentation	50	1 of 2
66794	butanoate fermentation	50	2 of 4
66794	phenylmercury acetate degradation	50	1 of 2
66794	phenylpropanoid biosynthesis	46.15	6 of 13
66794	vitamin B6 metabolism	45.45	5 of 11
66794	degradation of aromatic, nitrogen containing compounds	41.67	5 of 12
66794	arachidonate biosynthesis	40	2 of 5
66794	glycine metabolism	40	4 of 10
66794	4-hydroxyphenylacetate degradation	40	4 of 10
66794	creatinine degradation	40	2 of 5
66794	myo-inositol biosynthesis	40	4 of 10
66794	phosphatidylethanolamine bioynthesis	38.46	5 of 13
66794	carnitine metabolism	37.5	3 of 8
66794	cyanate degradation	33.33	1 of 3
66794	sphingosine metabolism	33.33	2 of 6
66794	sulfoquinovose degradation	33.33	1 of 3
66794	IAA biosynthesis	33.33	1 of 3
66794	lipid A biosynthesis	33.33	3 of 9
66794	nitrate assimilation	33.33	3 of 9
66794	(5R)-carbapenem carboxylate biosynthesis	33.33	1 of 3
66794	coenzyme M biosynthesis	30	3 of 10
66794	bile acid biosynthesis, neutral pathway	29.41	5 of 17
66794	benzoyl-CoA degradation	28.57	2 of 7
66794	cholesterol biosynthesis	27.27	3 of 11
66794	dolichyl-diphosphooligosaccharide biosynthesis	27.27	3 of 11
66794	carotenoid biosynthesis	27.27	6 of 22
66794	polyamine pathway	26.09	6 of 23
66794	CMP-KDO biosynthesis	25	1 of 4
66794	biotin biosynthesis	25	1 of 4
66794	toluene degradation	25	1 of 4
66794	phenol degradation	25	5 of 20
66794	androgen and estrogen metabolism	25	4 of 16
66794	catecholamine biosynthesis	25	1 of 4
66794	sulfate reduction	23.08	3 of 13
66794	chlorophyll metabolism	22.22	4 of 18
66794	4-hydroxymandelate degradation	22.22	2 of 9
66794	arachidonic acid metabolism	22.22	4 of 18

API 20E

API coryne

API zym

Isolation source categories

Isolation

Taxonmaps

69479

Global distribution of 16S sequence X83810 (>99% sequence identity) for Brachybacterium faecium from Microbeatlas

Aquatic Samples	66
Soil Samples	60
Animal Samples	1056
Plant Samples	45
Total Samples	1227

Risk assessment

Genome sequences

@ref	Description	Assembly level	INSDC accession	BV-BRC accession	IMG accession	NCBI tax ID	Score
66792	ASM2340v1 assembly for Brachybacterium faecium DSM 4810	complete	GCA_000023405	446465.5	644736331	446465	73.89

16S sequences

@ref	Description	Accession	Length	Database	NCBI tax ID
20218	B.faecium 16S rRNA gene	X83810	1480		446465
1836	B.faecium 16S ribosomal RNA gene	X91032	1513		446465

GC content

Predictions

Literature

Topic	Title	Authors	Journal	DOI	Year
Genetics	High intra-laboratory reproducibility of nanopore sequencing in bacterial species underscores advances in its accuracy.	Abdel-Glil MY, Brandt C, Pletz MW, Neubauer H, Sprague LD.	Microb Genom	10.1099/mgen.0.001372	2025
	Genome Sequence of Acinetobacter towneri Strain DSM 16313, Previously Known as the Proposed Type Strain of Acinetobacter seohaensis.	Maehana S, Kitasato H, Suzuki M.	Microbiol Resour Announc	10.1128/mra.00690-21	2021
	Effects of oral Enterococcus faecium strain DSM 10663 NCIMB 10415 on diarrhoea patterns and performance of sucking piglets.	Busing K, Zeyner A.	Benef Microbes	10.3920/bm2014.0008	2015
	Selective isolation and genomic characterization of biopolymer producer-a novel feature of halophile Brachybacterium paraconglomeratum MTCC 13074.	Mandragutti T, Sudhakar G.	J Genet Eng Biotechnol	10.1186/s43141-023-00484-y	2023
	Establishment of a Real-Time PCR Assay for the Detection of Devriesea agamarum in Lizards.	Brockmann M, Leineweber C, Hellebuyck T, Martel A, Pasmans F, Gentil M, Muller E, Marschang RE.	Animals (Basel)	10.3390/ani13050881	2023
	Gut commensal Phascolarctobacterium faecium retunes innate immunity to mitigate obesity and metabolic disease in mice.	Liebana-Garcia R, Lopez-Almela I, Olivares M, Romani-Perez M, Manghi P, Torres-Mayo A, Tolosa-Enguis V, Flor-Duro A, Bullich-Vilarrubias C, Rubio T, Rossini V, Segata N, Sanz Y.	Nat Microbiol	10.1038/s41564-025-01989-7	2025
	The Liver Microbiome Is Implicated in Cancer Prognosis and Modulated by Alcohol and Hepatitis B.	Chakladar J, Wong LM, Kuo SZ, Li WT, Yu MA, Chang EY, Wang XQ, Ongkeko WM.	Cancers (Basel)	10.3390/cancers12061642	2020
Metabolism	Development and validation of a microarray for the investigation of the CAZymes encoded by the human gut microbiome.	El Kaoutari A, Armougom F, Leroy Q, Vialettes B, Million M, Raoult D, Henrissat B.	PLoS One	10.1371/journal.pone.0084033	2013
Pathogenicity	Probiotic Potential of the Marine Isolate Enterococcus faecium EA9 and In Vivo Evaluation of Its Antisepsis Action in Rats.	Zaghloul EH, Abuohashish HM, El Sharkawy AS, Abbas EM, Ahmed MM, Al-Rejaie SS.	Mar Drugs	10.3390/md21010045	2023
	Phylogenetically diverse bacteria isolated from tattoo inks, an azo dye-rich environment, decolorize a wide range of azo dyes.	Nho SW, Cui X, Kweon O, Jin J, Chen H, Moon MS, Kim SJ, Cerniglia CE.	Ann Microbiol	10.1186/s13213-021-01648-2	2021
Metabolism	Light-inducible carotenoid production controlled by a MarR-type regulator in Corynebacterium glutamicum.	Sumi S, Suzuki Y, Matsuki T, Yamamoto T, Tsuruta Y, Mise K, Kawamura T, Ito Y, Shimada Y, Watanabe E, Watanabe S, Toriyabe M, Takano Shiratori H, Ueda K, Takano H.	Sci Rep	10.1038/s41598-019-49384-7	2019
	Antibacterial Activity of Three Extra Virgin Olive Oils of the Campania Region, Southern Italy, Related to Their Polyphenol Content and Composition.	Nazzaro F, Fratianni F, Cozzolino R, Martignetti A, Malorni L, De Feo V, Cruz AG, d'Acierno A.	Microorganisms	10.3390/microorganisms7090321	2019
	Analysis of EAWAG-BBD pathway prediction system for the identification of malathion degrading microbes.	Sivakumar S, Anitha P, Ramesh B, Suresh G.	Bioinformation	10.6026/97320630013073	2017
	Design, Synthesis and Antimicrobial Evaluation of New N-(1-Hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-6-yl)(hetero)aryl-2-carboxamides as Potential Inhibitors of Mycobacterial Leucyl-tRNA Synthetase.	Slechta P, Needle AA, Jand'ourek O, Paterova P, Konecna K, Barta P, Kunes J, Kubicek V, Dolezal M, Kucerova-Chlupacova M.	Int J Mol Sci	10.3390/ijms24032951	2023
	Data from computational analysis of the peptide linkers in the MocR bacterial transcriptional regulators.	Angelaccio S, Milano T, Tramonti A, Di Salvo ML, Contestabile R, Pascarella S.	Data Brief	10.1016/j.dib.2016.08.064	2016
Metabolism	Antibiotic resistance is prevalent in an isolated cave microbiome.	Bhullar K, Waglechner N, Pawlowski A, Koteva K, Banks ED, Johnston MD, Barton HA, Wright GD.	PLoS One	10.1371/journal.pone.0034953	2012
	Design, Synthesis and Biological Evaluation of New Piperazin-4-yl-(acetyl-thiazolidine-2,4-dione) Norfloxacin Analogues as Antimicrobial Agents.	Marc G, Araniciu C, Oniga SD, Vlase L, Pirnau A, Nadas GC, Novac CS, Matei IA, Chifiriuc MC, Marutescu L, Oniga O.	Molecules	10.3390/molecules24213959	2019
	Conservation analysis of the CydX protein yields insights into small protein identification and evolution.	Allen RJ, Brenner EP, VanOrsdel CE, Hobson JJ, Hearn DJ, Hemm MR.	BMC Genomics	10.1186/1471-2164-15-946	2014
Enzymology	Quantification of Propionibacterium acidipropionici P169 bacteria in environmental samples by use of strain-specific primers derived by suppressive subtractive hybridization.	Peng M, Smith AH, Rehberger TG.	Appl Environ Microbiol	10.1128/aem.02586-10	2011
	Early-Life Immune System Maturation in Chickens Using a Synthetic Community of Cultured Gut Bacteria.	Zenner C, Hitch TCA, Riedel T, Wortmann E, Tiede S, Buhl EM, Abt B, Neuhaus K, Velge P, Overmann J, Kaspers B, Clavel T.	mSystems	10.1128/msystems.01300-20	2021
Metabolism	Isolation of Terrabacter sp. strain DDE-1, which metabolizes 1, 1-dichloro-2,2-bis(4-chlorophenyl)ethylene when induced with biphenyl.	Aislabie J, Davison AD, Boul HL, Franzmann PD, Jardine DR, Karuso P.	Appl Environ Microbiol	10.1128/aem.65.12.5607-5611.1999	1999
	Annotation of Protein Domains Reveals Remarkable Conservation in the Functional Make up of Proteomes Across Superkingdoms.	Nasir A, Naeem A, Khan MJ, Nicora HD, Caetano-Anolles G.	Genes (Basel)	10.3390/genes2040869	2011
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Genetics	Genomic basis for natural product biosynthetic diversity in the actinomycetes.	Nett M, Ikeda H, Moore BS.	Nat Prod Rep	10.1039/b817069j	2009
Genetics	Developmental biology of Streptomyces from the perspective of 100 actinobacterial genome sequences.	Chandra G, Chater KF.	FEMS Microbiol Rev	10.1111/1574-6976.12047	2014
	A novel extracellular metallopeptidase domain shared by animal host-associated mutualistic and pathogenic microbes.	Nakjang S, Ndeh DA, Wipat A, Bolam DN, Hirt RP.	PLoS One	10.1371/journal.pone.0030287	2012
Phylogeny	Phylogenetic framework and molecular signatures for the main clades of the phylum Actinobacteria.	Gao B, Gupta RS.	Microbiol Mol Biol Rev	10.1128/mmbr.05011-11	2012
	Decoding oral leukoplakia: microbiome dysbiosis and inflammatory dynamics unveiled in a rat model.	Sang Z, Zhang Y, Kao E, Zhu T, Yang J, Xu ZZ, Huang S, Teng F, Wang W.	Front Microbiol	10.3389/fmicb.2025.1613165	2025
	A pilot RNA-seq study in 40 pietrain ejaculates to characterize the porcine sperm microbiome.	Godia M, Ramayo-Caldas Y, Zingaretti LM, Darwich L, Lopez S, Rodriguez-Gil JE, Yeste M, Sanchez A, Clop A.	Theriogenology	10.1016/j.theriogenology.2020.08.001	2020
	Advancements in understanding tumor-resident bacteria and their application in cancer therapy.	Luo YC, Huang XT, Wang R, Lin YJ, Sun JX, Li KF, Wang DY, Yan Y, Qiao YK.	Mil Med Res	10.1186/s40779-025-00623-1	2025
	Brachybacterium nesterenkovii isolated from a human blood culture-a first report.	Brummaier T, Hinfothong P, Soe NL, Tongmanakit J, Watthanaworawit W, Ling C.	New Microbes New Infect	10.1016/j.nmni.2020.100699	2020
	Correlation of distribution characteristics and dynamic changes of gut microbiota with the efficacy of immunotherapy in EGFR-mutated non-small cell lung cancer.	Luo WC, Mei SQ, Huang ZJ, Chen ZH, Zhang YC, Yang MY, Liu JQ, Xu JY, Yang XR, Zhong RW, Tang LB, Yin LX, Deng Y, Peng YL, Lu C, Chen BL, Ke DX, Tu HY, Yang JJ, Xu CR, Wu YL, Zhou Q.	J Transl Med	10.1186/s12967-024-05135-5	2024
Genetics	First metagenomic analysis of the Andean condor (Vultur gryphus) gut microbiome reveals microbial diversity and wide resistome.	Martinez-Hernandez JE, Berrios P, Santibanez R, Cuesta Astroz Y, Sanchez C, Martin AJM, Trombert AN.	PeerJ	10.7717/peerj.15235	2023
	Carbohydrate-active enzyme profiles of Lactiplantibacillus plantarum strain 84-3 contribute to flavor formation in fermented dairy and vegetable products.	Liang T, Jiang T, Liang Z, Zhang N, Dong B, Wu Q, Gu B.	Food Chem X	10.1016/j.fochx.2023.101036	2023
	Succession, Replacement, and Modification of Chicken Litter Microbiota.	Kubasova T, Faldynova M, Crhanova M, Karasova D, Zeman M, Babak V, Rychlik I.	Appl Environ Microbiol	10.1128/aem.01809-22	2022
	Bacteria and Boar Semen Storage: Progress and Challenges.	Contreras MJ, Nunez-Montero K, Bruna P, Garcia M, Leal K, Barrientos L, Weber H.	Antibiotics (Basel)	10.3390/antibiotics11121796	2022
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Genetics	Shotgun metagenomic sequencing reveals the influence of artisanal dairy environments on the microbiomes, quality, and safety of Idiazabal, a raw ewe milk PDO cheese.	Santamarina-Garcia G, Yap M, Crispie F, Amores G, Lordan C, Virto M, Cotter PD.	Microbiome	10.1186/s40168-024-01980-0	2024
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Pathogenicity	Bidirectional Mediation Effects between Intratumoral Microbiome and Host DNA Methylation Changes Contribute to Stomach Adenocarcinoma.	Yue K, Sheng D, Xue X, Zhao L, Zhao G, Jin C, Zhang L.	Microbiol Spectr	10.1128/spectrum.00904-23	2023
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Genetics	Genetic and functional diversity of beta-N-acetylgalactosamine-targeting glycosidases expanded by deep-sea metagenome analysis.	Sumida T, Hiraoka S, Usui K, Ishiwata A, Sengoku T, Stubbs KA, Tanaka K, Deguchi S, Fushinobu S, Nunoura T.	Nat Commun	10.1038/s41467-024-47653-2	2024
Phylogeny	Microbiota in Goat Buck Ejaculates Differs Between Breeding and Non-breeding Seasons.	Moce ML, Esteve IC, Perez-Fuentes S, Gomez EA, Moce E.	Front Vet Sci	10.3389/fvets.2022.867671	2022
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	Bacteremic Community-Acquired Pneumonia in Ethiopian Children: Etiology, Antibiotic Resistance, Risk Factors, and Clinical Outcome.	Negash AA, Asrat D, Abebe W, Hailemariam T, Hailu T, Aseffa A, Vaneechoutte M.	Open Forum Infect Dis	10.1093/ofid/ofz029	2019
Metabolism	Guiding the Refinement of Biochemical Knowledgebases with Ensembles of Metabolic Networks and Machine Learning.	Medlock GL, Papin JA.	Cell Syst	10.1016/j.cels.2019.11.006	2020
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Metabolism	The exo-beta-N-acetylmuramidase NamZ from Bacillus subtilis is the founding member of a family of exo-lytic peptidoglycan hexosaminidases.	Muller M, Calvert M, Hottmann I, Kluj RM, Teufel T, Balbuchta K, Engelbrecht A, Selim KA, Xu Q, Borisova M, Titz A, Mayer C.	J Biol Chem	10.1016/j.jbc.2021.100519	2021
	Comparison of Aqueous and Alcohol-based Agents for Presurgical Skin Preparation Methods in Mice.	Del Valle JM, Fisk EA, Noland EL, Pak D, Zhang J, Crim MJ, Lawrence FR, Hankenson FC.	J Am Assoc Lab Anim Sci	10.30802/aalas-jaalas-17-000128	2018
Phylogeny	Characteristics of CDC group 3 and group 5 coryneform bacteria isolated from clinical specimens and assignment to the genus Dermabacter.	Funke G, Stubbs S, Pfyffer GE, Marchiani M, Collins MD.	J Clin Microbiol	10.1128/jcm.32.5.1223-1228.1994	1994
Enzymology	Discovery of novel enzymes with industrial potential from a cold and alkaline environment by a combination of functional metagenomics and culturing.	Vester JK, Glaring MA, Stougaard P.	Microb Cell Fact	10.1186/1475-2859-13-72	2014
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Genetics	Genome-Based Taxonomic Classification of the Phylum Actinobacteria.	Nouioui I, Carro L, Garcia-Lopez M, Meier-Kolthoff JP, Woyke T, Kyrpides NC, Pukall R, Klenk HP, Goodfellow M, Goker M.	Front Microbiol	10.3389/fmicb.2018.02007	2018
Genetics	Complete genome sequence of Brachybacterium faecium type strain (Schefferle 6-10).	Lapidus A, Pukall R, Labuttii K, Copeland A, Del Rio TG, Nolan M, Chen F, Lucas S, Tice H, Cheng JF, Bruce D, Goodwin L, Pitluck S, Rohde M, Goker M, Pati A, Ivanova N, Mavrommatis K, Chen A, Palaniappan K, D'haeseleer P, Chain P, Bristow J, Eisen JA, Markowitz V, Hugenholtz P, Kyrpides NC, Klenk HP	Stand Genomic Sci	10.4056/sigs.492	2009
Genetics	Brachybacterium timonense sp. nov., a new bacterium isolated from human sputum.	Kuete E, Mbogning Fonkou MD, Mekhalif F, Anani H, Baudoin JP, Raoult D, Bou Khalil JY.	New Microbes New Infect	10.1016/j.nmni.2019.100568	2019
Genetics	Brachybacterium massiliense sp. nov., a new bacterium isolated from stool from a healthy Senegalese child.	Mekhalif F, Tidjani Alou M, Zgheib R, Lo CI, Fournier PE, Raoult D, Lagier JC.	New Microbes New Infect	10.1016/j.nmni.2019.100588	2019
Phylogeny	Two coryneform bacteria isolated from the surface of French Gruyère and Beaufort cheeses are new species of the genus Brachybacterium: Brachybacterium alimentarium sp. nov. and Brachybacterium tyrofermentans sp. nov.	Schubert K, Ludwig W, Springer N, Kroppenstedt RM, Accolas JP, Fiedler F.	Int J Syst Bacteriol	10.1099/00207713-46-1-81	1996
Phylogeny	Taxonomic study of the genus Brachybacterium: Brachybacterium nesterenkovii sp. nov.	Gvozdyak OR, Nogina TM, Schumann P.	Int J Syst Bacteriol	10.1099/00207713-42-1-74	1992
Phylogeny	Brachybacterium aquaticum sp. nov., a novel actinobacterium isolated from seawater.	Kaur G, Kumar N, Mual P, Kumar A, Kumar RM, Mayilraj S	Int J Syst Evol Microbiol	10.1099/ijsem.0.001414	2016
Phylogeny	Brachybacterium hainanense sp. nov., isolated from noni (Morinda citrifolia L.) branch.	Liu Y, Zhai L, Yao S, Cao Y, Cao Y, Zhang X, Su J, Ge Y, Zhao R, Cheng C	Int J Syst Evol Microbiol	10.1099/ijsem.0.000559	2015
Phylogeny	Brachybacterium ginsengisoli sp. nov., isolated from soil of a ginseng field.	Hoang VA, Kim YJ, Nguyen NL, Yang DC	Int J Syst Evol Microbiol	10.1099/ijs.0.058388-0	2014
Phylogeny	Brachybacterium saurashtrense sp. nov., a halotolerant root-associated bacterium with plant growth-promoting potential.	Gontia I, Kavita K, Schmid M, Hartmann A, Jha B	Int J Syst Evol Microbiol	10.1099/ijs.0.023176-0	2011
Phylogeny	Devriesea agamarum gen. nov., sp. nov., a novel actinobacterium associated with dermatitis and septicaemia in agamid lizards.	Martel A, Pasmans F, Hellebuyck T, Haesebrouck F, Vandamme P	Int J Syst Evol Microbiol	10.1099/ijs.0.65478-0	2008