Corynebacterium simulans (DSM 44415, ATCC BAA-15, CCUG 43305)

Cell morphology

Colony morphology

Multicellular morphology

Multimedia

• @ref:	11538
  multimedia content:	DSM_44415.jpg
  multimedia.multimedia content:	https://www.dsmz.de/microorganisms/photos/DSM_44415.jpg
  caption:	Medium 693 37°C
  intellectual property rights:	© Leibniz-Institut DSMZ
  manual_annotation:	1

Culture medium

@ref	Name	Growth	Medium link	Composition
11538	COLUMBIA BLOOD MEDIUM (DSMZ Medium 693)		Medium recipe at MediaDive	Name: COLUMBIA BLOOD MEDIUM (DSMZ Medium 693) Composition: Defibrinated sheep blood 50.0 g/l Columbia agar base
20057	ISP 2			Name: ISP 2 / Yeast Malt Agar (5265); 5265 Composition Malt extract 10.0 g/l Yeast extract 4.0 g/l Glucose 4.0 g/l Agar 15.0 g/l Preparation: Sterilisation: 20 minutes at 121°C pH before sterilisation: 7.0 Usage: Maintenance and Taxonomy Organisms: All Actinomycetes
20057	ISP 3			Name: ISP 3; 5315 Composition Dog oat flakes 20.0 g/l Trace element solution (5314) 2.5 ml/l Agar 18.0 g/l Preparation: Oat flakes are cooked for 20 minutes, trace element solution and agar are added (in the case of non rolled oat flakes the suspension has to bee filtrated). Sterilisation: 20 minutes at 121°C pH before sterilisation: 7.8 Usage: Maintenance and taxonomy (e.g. SEM As liquid medium for metabolite production) Organisms: All Actinomycetes Trace element solution 5314 Name: Trace element solution 5314; 5314 Composition CaCl2 x H2O 3.0 g/l Fe-III-citrate 1.0 g/l MnSO4 0.2 g/l ZnCl2 0.1 g/l CuSO4 x 5 H2O 0.025 g/l Sodium tetra borate 0.2 g/l CoCl2 x 6 H2O 0.004 g/l Sodium molybdate 0.01 g/l Preparation: Use double destillated water. Sterilisation: 20 minutes at 121°C pH before sterilisation: Usage: Trace element solution for different media Organisms:
20057	ISP 4			Name: ISP 4; DSM 547 Solution I: Difco soluble starch, 10.0 g. Make a paste of the starch with a small amount of cold distilled water and bring to a volume of 500 ml. Solution II: CaCO3 2.0 g K2HPO4 (anhydrous) 1.0 g MgSO4 x 7 H2O 1.0 g NaCl 1.0 g (NH4)2SO4 2.0 g Distilled water 500.0 ml Trace salt solution (see below) 1.0 ml The pH should be between 7.0 and 7.4. Do not adjust if it is within this range. Mix solutions I and II together. Add 20.0 g agar. Liquify agar by steaming at 100°C for 10 to 20 min. Trace element solution: FeSO4 x 7 H2O 0.1 g MnCl2 x 4 H2O 0.1 g ZnSO4 x 7 H2O 0.1 g Distilled water 100.0 ml
20057	ISP 5			Name: ISP 5 (5323) Composition L-Asparagine 1.0 g/l Glycerol 10.0 g/l K2HPO4 1.0 g/l Salt solution (see preparation) 1.0 ml/l Agar 20.0 g/l Preparation: Salt solution 1.0 g FeSO4 x 7 H2O 1.0 g MnCl2 x 4 H2O 1.0 g ZNSO4 x 7 H2O in 100 ml water Sterilisation: 20 minutes at 121°C pH before sterilisation: 7.2 Usage: Maintenance and taxonomy Organisms: All Actinomycetes
20057	ISP 6			Name: ISP 6 (5318) Composition Peptone 15.0 g/l Proteose peptose 5.0 g/l Ferric ammonium citrate 0.5 g/l Sodium glycerophosphate 1.0 g/l Sodium thiosulfate 0.08 g/l Yeast extract 1.0 g/l Agar 15.0 g/l Sterilisation: 20 minutes at 121°C pH before sterilisation: Usage: Production of melanoid pigments Organisms: All Actinomycetes
20057	ISP 7			Name: ISP 7 (5322) Composition Glycerol 15.0 g/l L-Tyrosine 0.5 g/l L-Asparagine 1.0 g/l K2HPO4 0.5 g/l NaCl 0.5 g/l FeSO4 x 7 H2O 0.01 g/l Trace element solution 5343 1.0 ml/l Agar 20.0 Sterilisation: 20 minutes at 121°C pH before sterilisation: 7.3 Usage: Production of melanoid pigments Organisms: All Actinomycetes
23183	blood agar
39539	MEDIUM 6 - Columbia agar with 10 % horse blood			Distilled water make up to (1000.000 ml);Columbia agar (39.000 g);Horseblood (100.000 ml)
122623	CIP Medium 6		Medium recipe at CIP
11538	TRYPTICASE SOY YEAST EXTRACT MEDIUM (DSMZ Medium 92)		Medium recipe at MediaDive	Name: TRYPTICASE SOY YEAST EXTRACT MEDIUM (DSMZ Medium 92) Composition: Trypticase soy broth 30.0 g/l Agar 15.0 g/l Yeast extract 3.0 g/l Distilled water

Culture temp

Oxygen tolerance

Spore formation

Halophily

Metabolite utilization

@ref	Chebi-ID	Metabolite	Utilization activity	Kind of utilization tested
23183	16808 ChEBI	2-dehydro-D-gluconate	-	builds acid from
23183	17426 ChEBI	5-dehydro-D-gluconate	-	builds acid from
23183	27613 ChEBI	amygdalin	-	builds acid from
68371	27613 ChEBI	amygdalin	-	builds acid from	from API 50CH acid
23183	18305 ChEBI	arbutin	-	builds acid from
68371	18305 ChEBI	arbutin	-	builds acid from	from API 50CH acid
23183	17057 ChEBI	cellobiose	-	builds acid from
68371	17057 ChEBI	cellobiose	-	builds acid from	from API 50CH acid
23183	17108 ChEBI	D-arabinose	-	builds acid from
68371	17108 ChEBI	D-arabinose	-	builds acid from	from API 50CH acid
23183	18333 ChEBI	D-arabitol	-	builds acid from
68371	18333 ChEBI	D-arabitol	-	builds acid from	from API 50CH acid
68371	15824 ChEBI	D-fructose	+	builds acid from	from API 50CH acid
23183	28847 ChEBI	D-fucose	-	builds acid from
68371	28847 ChEBI	D-fucose	-	builds acid from	from API 50CH acid
68371	12936 ChEBI	D-galactose	+	builds acid from	from API 50CH acid
68371	17634 ChEBI	D-glucose	+	builds acid from	from API 50CH acid
23183	62318 ChEBI	D-lyxose	-	builds acid from
68371	62318 ChEBI	D-lyxose	-	builds acid from	from API 50CH acid
68379	16899 ChEBI	D-mannitol	-	fermentation	from API Coryne
68371	16899 ChEBI	D-mannitol	-	builds acid from	from API 50CH acid
68371	16024 ChEBI	D-mannose	+	builds acid from	from API 50CH acid
68371	16988 ChEBI	D-ribose	+	builds acid from	from API 50CH acid
68371	17924 ChEBI	D-sorbitol	-	builds acid from	from API 50CH acid
23183	16443 ChEBI	D-tagatose	-	builds acid from
68371	16443 ChEBI	D-tagatose	-	builds acid from	from API 50CH acid
23183	65327 ChEBI	D-xylose	-	builds acid from
68379	65327 ChEBI	D-xylose	-	fermentation	from API Coryne
68371	65327 ChEBI	D-xylose	-	builds acid from	from API 50CH acid
23183	17113 ChEBI	erythritol	-	builds acid from
68371	17113 ChEBI	erythritol	-	builds acid from	from API 50CH acid
23183	4853 ChEBI	esculin	-	builds acid from
23183	4853 ChEBI	esculin	-	hydrolysis
68379	4853 ChEBI	esculin	-	hydrolysis	from API Coryne
122623	4853 ChEBI	esculin	-	hydrolysis
68371	4853 ChEBI	esculin	-	builds acid from	from API 50CH acid
23183	30742 ChEBI	ethylene glycol	-	builds acid from
23183	28757 ChEBI	fructose	+	builds acid from
23183	16813 ChEBI	galactitol	-	builds acid from
68371	16813 ChEBI	galactitol	-	builds acid from	from API 50CH acid
23183	28260 ChEBI	galactose	+/-	builds acid from
23183	5291 ChEBI	gelatin	-	hydrolysis
68379	5291 ChEBI	gelatin	-	hydrolysis	from API Coryne
23183	28066 ChEBI	gentiobiose	-	builds acid from
68371	28066 ChEBI	gentiobiose	-	builds acid from	from API 50CH acid
23183	24265 ChEBI	gluconate	-	builds acid from
68371	24265 ChEBI	gluconate	-	builds acid from	from API 50CH acid
23183	17234 ChEBI	glucose	+	builds acid from
23183	17754 ChEBI	glycerol	-	builds acid from
68371	17754 ChEBI	glycerol	-	builds acid from	from API 50CH acid
23183	28087 ChEBI	glycogen	-	builds acid from
68379	28087 ChEBI	glycogen	-	fermentation	from API Coryne
68371	28087 ChEBI	glycogen	-	builds acid from	from API 50CH acid
122623	606565 ChEBI	hippurate	+	hydrolysis
23183	15443 ChEBI	inulin	-	builds acid from
68371	15443 ChEBI	inulin	-	builds acid from	from API 50CH acid
23183	30849 ChEBI	L-arabinose	-	builds acid from
68371	30849 ChEBI	L-arabinose	-	builds acid from	from API 50CH acid
23183	18403 ChEBI	L-arabitol	-	builds acid from
68371	18403 ChEBI	L-arabitol	-	builds acid from	from API 50CH acid
23183	18287 ChEBI	L-fucose	-	builds acid from
68371	18287 ChEBI	L-fucose	-	builds acid from	from API 50CH acid
68371	62345 ChEBI	L-rhamnose	-	builds acid from	from API 50CH acid
68371	17266 ChEBI	L-sorbose	-	builds acid from	from API 50CH acid
23183	65328 ChEBI	L-xylose	-	builds acid from
68371	65328 ChEBI	L-xylose	-	builds acid from	from API 50CH acid
23183	17716 ChEBI	lactose	-	builds acid from
68379	17716 ChEBI	lactose	-	fermentation	from API Coryne
68371	17716 ChEBI	lactose	-	builds acid from	from API 50CH acid
23183	17306 ChEBI	maltose	-	builds acid from
68379	17306 ChEBI	maltose	-	fermentation	from API Coryne
68371	17306 ChEBI	maltose	-	builds acid from	from API 50CH acid
23183	29864 ChEBI	mannitol	-	builds acid from
23183	37684 ChEBI	mannose	+	builds acid from
23183	6731 ChEBI	melezitose	-	builds acid from
68371	6731 ChEBI	melezitose	-	builds acid from	from API 50CH acid
23183	28053 ChEBI	melibiose	-	builds acid from
68371	28053 ChEBI	melibiose	-	builds acid from	from API 50CH acid
23183	320061 ChEBI	methyl alpha-D-glucopyranoside	-	builds acid from
68371	320061 ChEBI	methyl alpha-D-glucopyranoside	-	builds acid from	from API 50CH acid
23183	43943 ChEBI	methyl alpha-D-mannoside	-	builds acid from
68371	43943 ChEBI	methyl alpha-D-mannoside	-	builds acid from	from API 50CH acid
23183	74863 ChEBI	methyl beta-D-xylopyranoside	-	builds acid from
68371	74863 ChEBI	methyl beta-D-xylopyranoside	-	builds acid from	from API 50CH acid
23183	17268 ChEBI	myo-inositol	-	builds acid from
68371	17268 ChEBI	myo-inositol	-	builds acid from	from API 50CH acid
23183	506227 ChEBI	N-acetylglucosamine	+/-	builds acid from
68371	59640 ChEBI	N-acetylglucosamine	-	builds acid from	from API 50CH acid
23183	17632 ChEBI	nitrate	+	reduction
122623	17632 ChEBI	nitrate	+	reduction
122623	17632 ChEBI	nitrate	+	respiration
23183	16301 ChEBI	nitrite	+	reduction
122623	16301 ChEBI	nitrite	+	reduction
68371		Potassium 2-ketogluconate	-	builds acid from	from API 50CH acid
68371		Potassium 5-ketogluconate	-	builds acid from	from API 50CH acid
23183	16634 ChEBI	raffinose	-	builds acid from
68371	16634 ChEBI	raffinose	-	builds acid from	from API 50CH acid
23183	26546 ChEBI	rhamnose	-	builds acid from
23183	15963 ChEBI	ribitol	-	builds acid from
68371	15963 ChEBI	ribitol	-	builds acid from	from API 50CH acid
23183	33942 ChEBI	ribose	+/-	builds acid from
23183	17814 ChEBI	salicin	-	builds acid from
68371	17814 ChEBI	salicin	-	builds acid from	from API 50CH acid
23183	30911 ChEBI	sorbitol	-	builds acid from
23183	27922 ChEBI	sorbose	-	builds acid from
23183	28017 ChEBI	starch	-	builds acid from
68371	28017 ChEBI	starch	-	builds acid from	from API 50CH acid
23183	17992 ChEBI	sucrose	+	builds acid from
68371	17992 ChEBI	sucrose	+	builds acid from	from API 50CH acid
23183	27082 ChEBI	trehalose	-	builds acid from
68371	27082 ChEBI	trehalose	-	builds acid from	from API 50CH acid
23183	32528 ChEBI	turanose	-	builds acid from
68371	32528 ChEBI	turanose	-	builds acid from	from API 50CH acid
23183	16199 ChEBI	urea	-	hydrolysis
68379	16199 ChEBI	urea	-	hydrolysis	from API Coryne
23183	17151 ChEBI	xylitol	-	builds acid from
68371	17151 ChEBI	xylitol	-	builds acid from	from API 50CH acid

Metabolite production

@ref	Chebi-ID	Metabolite	Production
122623	35581 ChEBI	indole

Metabolite tests

@ref	Chebi-ID	Metabolite	Voges-proskauer-test	Methylred-test
122623	15688 ChEBI	acetoin	-
122623	17234 ChEBI	glucose		-

Enzymes

@ref	Value	Activity	Ec
23183	acid phosphatase	-	3.1.3.2
68382	acid phosphatase	+	3.1.3.2	from API zym
122623	alcohol dehydrogenase	-	1.1.1.1
23183	alkaline phosphatase	+	3.1.3.1
68382	alkaline phosphatase	+	3.1.3.1	from API zym
68379	alkaline phosphatase	+	3.1.3.1	from API Coryne
68382	alpha-chymotrypsin	-	3.4.21.1	from API zym
23183	alpha-fucosidase	-	3.2.1.51
68382	alpha-fucosidase	-	3.2.1.51	from API zym
23183	alpha-galactosidase	-	3.2.1.22
68382	alpha-galactosidase	-	3.2.1.22	from API zym
23183	alpha-glucosidase	-	3.2.1.20
68379	alpha-glucosidase	-	3.2.1.20	from API Coryne
23183	alpha-mannosidase	-	3.2.1.24
68382	alpha-mannosidase	-	3.2.1.24	from API zym
122623	amylase	-
23183	beta-galactosidase	-	3.2.1.23
68382	beta-galactosidase	-	3.2.1.23	from API zym
122623	beta-galactosidase	-	3.2.1.23
68379	beta-galactosidase	-	3.2.1.23	from API Coryne
23183	beta-glucosidase	-	3.2.1.21
68382	beta-glucosidase	-	3.2.1.21	from API zym
68379	beta-glucosidase	-	3.2.1.21	from API Coryne
23183	beta-glucuronidase	-	3.2.1.31
68382	beta-glucuronidase	-	3.2.1.31	from API zym
68379	beta-glucuronidase	-	3.2.1.31	from API Coryne
122623	caseinase	-	3.4.21.50
23183	catalase	+	1.11.1.6
122623	catalase	+	1.11.1.6
68379	catalase	+	1.11.1.6	from API Coryne
23183	chymotrypsin	-	3.4.4.5
23183	cystine arylamidase	-	3.4.11.3
68382	cystine arylamidase	-	3.4.11.3	from API zym
122623	DNase	-
23183	esterase	+
68382	esterase (C 4)	+		from API zym
23183	esterase lipase (C 8)	+
68382	esterase lipase (C 8)	+		from API zym
122623	gamma-glutamyltransferase	-	2.3.2.2
122623	gelatinase	-
68379	gelatinase	-		from API Coryne
122623	lecithinase	-
23183	leucine arylamidase	+	3.4.11.1
68382	leucine arylamidase	+	3.4.11.1	from API zym
23183	lipase	-
122623	lipase	-
68382	lipase (C 14)	-		from API zym
122623	lysine decarboxylase	-	4.1.1.18
23183	N-acetyl-beta-glucosaminidase	-	3.2.1.52
68382	N-acetyl-beta-glucosaminidase	-	3.2.1.52	from API zym
68379	N-acetyl-beta-glucosaminidase	-	3.2.1.52	from API Coryne
23183	naphthol-AS-BI-phosphohydrolase	+
68382	naphthol-AS-BI-phosphohydrolase	+		from API zym
122623	ornithine decarboxylase	-	4.1.1.17
122623	oxidase	+
122623	phenylalanine ammonia-lyase	-	4.3.1.24
23183	pyrazinamidase	+/-	3.5.1.B15
68379	pyrazinamidase	-	3.5.1.B15	from API Coryne
68379	pyrrolidonyl arylamidase	-	3.4.19.3	from API Coryne
23183	trypsin	+	3.4.21.4
122623	tryptophan deaminase	-
122623	tween esterase	+
122623	urease	-	3.5.1.5
68379	urease	-	3.5.1.5	from API Coryne
23183	valine arylamidase	-

Fatty acid profile

Metadata FA analysis
type of FA analysis	whole cell analysis
method/protocol	CCUG
@ref	55780
Fatty acid Percentage ECL C18:1 ω9c 57.4 17.769 C16:0 21.6 16 C17:1 ω8c 12 16.792 C18:0 5 18 C16:1 ω11c 1.9 15.757 C18:2 ω6,9c/C18:0 ANTE 0.9 17.724 C16:1 ω7c 0.7 15.819 C19:1 ISO I 0.5 18.473

API coryne

API zym

API 50CHac

API biotype100

Isolation source categories

Isolation

Taxonmaps

69479

Global distribution of 16S sequence AJ012837 (>99% sequence identity) for Corynebacterium from Microbeatlas

Aquatic Samples	150
Soil Samples	163
Animal Samples	6994
Plant Samples	67
Total Samples	7374

Risk assessment

16S sequences

@ref	Description	Accession	Length	Database	NCBI tax ID
20218	Corynebacterium simulans gene for 16S rRNA, partial sequence	AB470620	543		146827
23183	Corynebacterium sp. strain UCL553, 16S rRNA gene, partial	AJ012837	1468		146827

Literature

Topic	Title	Authors	Journal	DOI	Year
	Emulgel Containing Metronidazole and Clindamycin for the Treatment of Rosacea.	De Grau-Bassal G, Calpena-Campmany AC, Silva-Abreu M, Suner-Carbo J, Mallandrich-Miret M, Martinez-Ruiz S, Cordero C, Del Pozo A, Febrer NB.	Pharmaceutics	10.3390/pharmaceutics17020168	2025
Enzymology	Direct detection of Corynebacterium striatum, Corynebacterium propinquum, and Corynebacterium simulans in sputum samples by high-resolution melt curve analysis.	Xu S, Qiu X, Hou X, Zhou H, Chen D, Wang X, Han L, Li D, Sun L, Ji X, Li M, Zhang J, Li M, Li Z.	BMC Infect Dis	10.1186/s12879-020-05633-z	2021
Pathogenicity	Cationic Intrinsically Disordered Antimicrobial Peptides (CIDAMPs) Represent a New Paradigm of Innate Defense with a Potential for Novel Anti-Infectives.	Latendorf T, Gerstel U, Wu Z, Bartels J, Becker A, Tholey A, Schroder JM.	Sci Rep	10.1038/s41598-019-39219-w	2019
	Discovery of natural bispecific antibodies: Is psoriasis induced by a toxigenic Corynebacterium simulans and maintained by CIDAMPs as autoantigens?	Schroder JM.	Exp Dermatol	10.1111/exd.15014	2024
	Delayed onset of Corynebacterium simulans infection following open reduction and internal fixation of a trimalleolar fracture.	Tsivelekas K, Lykos S, Pallis D, Ampadiotaki MM, Nikolakakos P, Tilentzoglou A, Papadakis SA.	J Surg Case Rep	10.1093/jscr/rjae334	2024
Phylogeny	Primary Axillary Actinomycosis: A Case Report on the Integration of Culture and Molecular Diagnostics for Accurate Diagnosis of Polymicrobial Infections.	Tezuka J, Abe N, Tanabe H.	Microorganisms	10.3390/microorganisms13030671	2025
	Hidradenitis suppurativa induced by ipilimumab and nivolumab: A rare association.	Woods AD, Kim K, Axelson A.	JAAD Case Rep	10.1016/j.jdcr.2024.12.009	2025
	Taxonomic and functional profiling of the vulvar microbiome indicates variations related to ecological signatures, aging, and health status.	Mieremet A, van der Wurff M, Pagan L, Ferrer-Gonzalez E, Seo J, Schuren FHJ.	Front Microbiol	10.3389/fmicb.2025.1633147	2025
	Investigating Skin Microbial Community in Malignant Melanoma Lesions.	Properzi M, Dimartino V, Pietrucci D, Fontana C, Rotondo C, Lembo L, Ricci F, Scatozza F, Di Lella G, Messina F, Chillemi G, Bartolini B, Facchiano A.	Microorganisms	10.3390/microorganisms13050992	2025
	Diagnostic performance of an automated robot for MALDI target preparation in microbial identification.	Pranada AB, Cicatka M, Hess C, Karasek J.	J Clin Microbiol	10.1128/jcm.00434-24	2024
	A prospective evaluation of hidden bacterial involvement and antibiotic efficacy in nonbacterial CP/CPPS: addressing an underexplored therapeutic approach.	Kitano H, Ohge H, Tadera K, Kohada Y, Hatayama T, Shikuma H, Tasaka R, Takemoto K, Miyamoto S, Kobatake K, Sekino Y, Kitagawa H, Kashiyama S, Hinata N.	World J Urol	10.1007/s00345-025-05936-3	2025
Transcriptome	Exploratory multi-omics analysis reveals host-microbe interactions associated with disease severity in psoriatic skin.	Yang Y, Olah P, Radai Z, Maia G, Salava A, Salo V, Barker J, Lauerma A, Andersson B, Homey B, Fyhrquist N, Alenius H.	EBioMedicine	10.1016/j.ebiom.2024.105222	2024
Phylogeny	Source-tracking Klebsiella outbreaks in premature infants using a novel amplicon fingerprinting method.	Matson AP, Unterhauser K, Rezaul K, Lesmes S, Zhou Y, Michelow IC, Hussain N, Driscoll MD.	Antimicrob Resist Infect Control	10.1186/s13756-025-01609-3	2025
	Women Skin Microbiota Modifications during Pregnancy.	Radocchia G, Brunetti F, Marazzato M, Totino V, Neroni B, Bonfiglio G, Conte AL, Pantanella F, Ciolli P, Schippa S.	Microorganisms	10.3390/microorganisms12040808	2024
	Respiratory microbiome and clinical course of carbapenem-resistant Acinetobacter baumannii pneumonia in critically Ill patients.	Yoon JG, Lim S, Hyun HJ, Seong H, Noh JY, Song JY, Kim WJ, Cheong HJ.	Medicine (Baltimore)	10.1097/md.0000000000038988	2024
	Pyogenic spondylitis with acute course caused by Corynebacterium simulans.	Ogasawara M, Matsuhisa T, Kondo T, Oshima R, Sugiura F, Niwa T, Ando Y, Sato M, Sato J, Kohri S.	J Infect Chemother	10.1016/j.jiac.2019.10.012	2020
	Ocular surface disease related to tisotumab vedotin-tftv.	Lent-Schochet D, Tauber S, Seagrave Z, Paley GL, Farooq AV.	Gynecol Oncol Rep	10.1016/j.gore.2025.101676	2025
	Clinical characteristics of Corynebacterium simulans.	Ogasawara M, Matsuhisa T, Kondo T, Sato J.	Nagoya J Med Sci	10.18999/nagjms.83.2.269	2021
	Chronological age estimation from human microbiomes with transformer-based Robust Principal Component Analysis.	Myers T, Song SJ, Chen Y, De Pessemier B, Khatib L, McDonald D, Huang S, Gallo R, Callewaert C, Havulinna AS, Lahti L, Roeselers G, Laiola M, Shetty SA, Kelley ST, Knight R, Bartko A.	Commun Biol	10.1038/s42003-025-08590-y	2025
	Semen microbiota are dramatically altered in men with abnormal sperm parameters.	Osadchiy V, Belarmino A, Kianian R, Sigalos JT, Ancira JS, Kanie T, Mangum SF, Tipton CD, Hsieh TM, Mills JN, Eleswarapu SV.	Sci Rep	10.1038/s41598-024-51686-4	2024
	Diagnosis and Treatment to a Post-Craniotomy Intracranial Infection Caused by Corynebacterium.	Fan C, Gong L, An M, Li Z, Li X, Fang J.	Infect Drug Resist	10.2147/idr.s368857	2022
Pathogenicity	Alterations in the skin microbiome are associated with disease severity and treatment in the perioral zone of the skin of infants with atopic dermatitis.	Zheng Y, Wang Q, Ma L, Chen Y, Gao Y, Zhang G, Cui S, Liang H, He C, Song L.	Eur J Clin Microbiol Infect Dis	10.1007/s10096-019-03598-9	2019
	Clinical Features and Antibiotic Susceptibility of Staphylococcus aureus-Infected Dermatoses.	Koumaki D, Maraki S, Evangelou G, Koumaki V, Gregoriou S, Kouloumvakou S, Petrou D, Rovithi E, Zografaki K, Doxastaki A, Ioannou P, Gkiaouraki I, Rogdakis A, Mavromanolaki VE, Krasagakis K.	J Clin Med	10.3390/jcm14041084	2025
Phylogeny	Quantitative Aggregation of Microbiome Sequencing Data Provides Insights into the Associations between the Skin Microbiome and Psoriasis.	Chan AA, Tran PT, Lee DJ.	JID Innov	10.1016/j.xjidi.2023.100249	2024
	A Potential Predictive Role of the Scalp Microbiome Profiling in Patients with Alopecia Areata: Staphylococcus caprae, Corynebacterium, and Cutibacterium Species.	Won EJ, Jang HH, Park H, Kim SJ.	Microorganisms	10.3390/microorganisms10050864	2022
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Phylogeny	Temporal stability of tongue microbiota in older patients - A pilot study.	Tsai FT, Yang CC, Lin YC, Hsu ML, Hong G, Yang MC, Wang DH, Huang LJ, Lin CT, Hsu WE, Tu HF.	J Dent Sci	10.1016/j.jds.2024.01.012	2024
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	Bactericidal activities and biochemical features of 16 antimicrobial peptides against bovine-mastitis causative pathogens.	Cho HS, Kim D, Jeon H, Somasundaram P, Soundrarajan N, Park C.	Vet Res	10.1186/s13567-024-01402-x	2024
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Phylogeny	Pathogenic bacteria enriched in the oral microbiota might be associated with recurrent pulmonary infections in elderly individuals	Xu J, Qu R, Yang K, Wang Y, Nie M, Qi X, Zheng H, Yang L.	Aging Clin Exp Res		2025
	Milk microbiota of Holstein Friesian cattle reared in Lahore: Association with mastitis.	Salman MM, Nawaz M, Yaqub T, Mushtaq MH.	Saudi J Biol Sci	10.1016/j.sjbs.2024.103984	2024
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	Characterization of the Ocular Surface Microbiome in Keratitis Patients after Repeated Ophthalmic Antibiotic Exposure.	Kang Y, Tian L, Gu X, Chen Y, Ma X, Lin S, Li Z, Lou Y, Zheng M.	Microbiol Spectr	10.1128/spectrum.02162-21	2022
	Acute Pyogenic Spondylitis Caused by Streptococcus Constellatus in an Obese Patient: A Case Report.	Jin Y, Yin X.	Infect Drug Resist	10.2147/idr.s371411	2022
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	Surgical wound dehiscence complicated by methicillin-resistant Staphylococcus aureus infection in a diabetic patient with femorotibial vascular bypass occlusion.	Zardi EM, Montelione N, Vigliotti RC, Chello C, Zardi DM, Spinelli F, Stilo F.	Clin Med (Lond)	10.7861/clinmed.2019-0392	2020
Phylogeny	Thymopentapeptide Affects T-Cell Subsets by Modulating the Flora of the Skin Surface to Alleviate Psoriasis.	Liu X, Xi R, Du X, Wang Y, Cheng L, Yan G, Lu H, Liu T, Li F.	Drug Des Devel Ther	10.2147/dddt.s448550	2024
	Alterations of the Skin and Gut Microbiome in Psoriasis and Psoriatic Arthritis.	Olejniczak-Staruch I, Ciazynska M, Sobolewska-Sztychny D, Narbutt J, Skibinska M, Lesiak A.	Int J Mol Sci	10.3390/ijms22083998	2021
	Next-generation sequencing analysis of bacterial flora in bovine protothecal mastitic milk and feces.	Miura A, Kurumisawa T, Kano R, Ito T, Suzuki K, Kamata H.	J Vet Med Sci	10.1292/jvms.18-0649	2019
	Efficacy of 16S rRNA variable regions high-resolution melt analysis for bacterial pathogens identification in periprosthetic joint infections.	Bourbour S, Emaneini M, Jabalameli M, Mortazavi SMJ, Tahmasebi MN, Taghizadeh A, Sharafatvaziri A, Beigverdi R, Jabalameli F.	BMC Microbiol	10.1186/s12866-021-02164-8	2021
Genetics	Phenotypic and Genotypic Characterization of Cutibacterium acnes Isolated from Shoulder Surgery Reveals Insights into Genetic Diversity.	Kurihara MNL, Santos INM, Eisen AKA, Caleiro GS, Araujo J, Sales RO, Pignatari AC, Salles MJ.	Microorganisms	10.3390/microorganisms11102594	2023
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Genetics	Species- and strain-level diversity of Corynebacteria isolated from human facial skin.	Jensen MG, Svraka L, Baez E, Lund M, Poehlein A, Bruggemann H.	BMC Microbiol	10.1186/s12866-023-03129-9	2023
Phylogeny	Identification of fallopian tube microbiota and its association with ovarian cancer.	Yu B, Liu C, Proll SC, Manhardt E, Liang S, Srinivasan S, Swisher E, Fredricks DN.	Elife	10.7554/elife.89830	2024
Pathogenicity	Decrypting Skin Microbiome in Psoriasis: Current Status.	Arya P, Kaur M, Chosyang S, Kushwaha N, Singh B.	J Psoriasis Psoriatic Arthritis	10.1177/24755303231194293	2023
	Prokaryotic and eukaryotic skin microbiota modifications triggered by Leishmania infection in localized Cutaneous Leishmaniasis.	Jaimes J, Patino LH, Herrera G, Cruz C, Perez J, Correa-Cardenas CA, Munoz M, Ramirez JD.	PLoS Negl Trop Dis	10.1371/journal.pntd.0012029	2024
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	Novel configurations of type I-E CRISPR-Cas system in Corynebacterium striatum clinical isolates.	Ramos JN, Baio PVP, Veras JFC, Vieira EMD, Mattos-Guaraldi AL, Vieira VV.	Braz J Microbiol	10.1007/s42770-022-00881-4	2023
Genetics	Exploring strain diversity of dominant human skin bacterial species using single-cell genome sequencing.	Ide K, Saeki T, Arikawa K, Yoda T, Endoh T, Matsuhashi A, Takeyama H, Hosokawa M.	Front Microbiol	10.3389/fmicb.2022.955404	2022
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	Secretory IgA impacts the microbiota density in the human nose.	van Dalen R, Elsherbini AMA, Harms M, Alber S, Stemmler R, Peschel A.	Microbiome	10.1186/s40168-023-01675-y	2023
	Prevalence of Pathogens and Other Microorganisms in Premenopausal and Postmenopausal Women with Vulvovaginal Symptoms: A Retrospective Study in a Single Institute in South Korea.	Baek JC, Jo HC, Lee SM, Park JE, Cho IA, Sung JH.	Medicina (Kaunas)	10.3390/medicina57060577	2021
	Nasal commensals reduce Staphylococcus aureus proliferation by restricting siderophore availability.	Zhao Y, Bitzer A, Power JJ, Belikova D, Torres Salazar BO, Adolf LA, Gerlach D, Krismer B, Heilbronner S.	ISME J	10.1093/ismejo/wrae123	2024
Enzymology	High throughput in situ metagenomic measurement of bacterial replication at ultra-low sequencing coverage.	Emiola A, Oh J.	Nat Commun	10.1038/s41467-018-07240-8	2018
	Marjolin's Ulcer of the Tibia With Pelvic Lymph Node Metastasis.	Akoh CC, Chang J, Buckwalter J.	Iowa Orthop J		2017
Phylogeny	Role of Williamsia and Segniliparus in human infections with the approach taxonomy, cultivation, and identification methods.	Fatahi-Bafghi M.	Ann Clin Microbiol Antimicrob	10.1186/s12941-021-00416-z	2021
	Bacteria Modify Their Sensitivity to Chemerin-Derived Peptides by Hindering Peptide Association With the Cell Surface and Peptide Oxidation.	Godlewska U, Bilska B, Majewski P, Pyza E, Zabel BA, Cichy J.	Front Microbiol	10.3389/fmicb.2020.01819	2020
	Human milk microbiota in sub-acute lactational mastitis induces inflammation and undergoes changes in composition, diversity and load.	Boix-Amoros A, Hernandez-Aguilar MT, Artacho A, Collado MC, Mira A.	Sci Rep	10.1038/s41598-020-74719-0	2020
	Circulating Antibodies to Skin Bacteria Detected by Serological Lateral Flow Immunoassays Differentially Correlated With Bacterial Abundance.	Huang RY, Lee CN, Moochhala S.	Front Microbiol	10.3389/fmicb.2021.709562	2021
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	Potential Pathogenic Bacteria in Seminal Microbiota of Patients with Different Types of Dysspermatism.	Yang H, Zhang J, Xue Z, Zhao C, Lei L, Wen Y, Dong Y, Yang J, Zhang L.	Sci Rep	10.1038/s41598-020-63787-x	2020
Pathogenicity	In vitro Antimicrobial Activity of Acne Drugs Against Skin-Associated Bacteria.	Blaskovich MAT, Elliott AG, Kavanagh AM, Ramu S, Cooper MA.	Sci Rep	10.1038/s41598-019-50746-4	2019
	Resolving the Complexity of Human Skin Metagenomes Using Single-Molecule Sequencing.	Tsai YC, Conlan S, Deming C, NISC Comparative Sequencing Program, Segre JA, Kong HH, Korlach J, Oh J.	mBio	10.1128/mbio.01948-15	2016
	Bone and Joint Infection Involving Corynebacterium spp.: From Clinical Features to Pathophysiological Pathways.	Chauvelot P, Ferry T, Tafani V, Diot A, Tasse J, Conrad A, Chidiac C, Braun E, Lustig S, Laurent F, Valour F.	Front Med (Lausanne)	10.3389/fmed.2020.539501	2020
Pathogenicity	When Good Bugs Go Bad: Epidemiology and Antimicrobial Resistance Profiles of Corynebacterium striatum, an Emerging Multidrug-Resistant, Opportunistic Pathogen.	McMullen AR, Anderson N, Wallace MA, Shupe A, Burnham CA.	Antimicrob Agents Chemother	10.1128/aac.01111-17	2017
Metabolism	Psoriasis and Gut Microbiome-Current State of Art.	Polak K, Bergler-Czop B, Szczepanek M, Wojciechowska K, Fratczak A, Kiss N.	Int J Mol Sci	10.3390/ijms22094529	2021
Metabolism	Biogeography of Bacterial Communities and Specialized Metabolism in Human Aerodigestive Tract Microbiomes.	Stubbendieck RM, Zelasko SE, Safdar N, Currie CR.	Microbiol Spectr	10.1128/spectrum.01669-21	2021
	Lactobacillus Dominate in the Intestine of Atlantic Salmon Fed Dietary Probiotics.	Gupta S, Feckaninova A, Lokesh J, Koscova J, Sorensen M, Fernandes J, Kiron V.	Front Microbiol	10.3389/fmicb.2018.03247	2018
Enzymology	Characterization of the human skin resistome and identification of two microbiota cutotypes.	Li Z, Xia J, Jiang L, Tan Y, An Y, Zhu X, Ruan J, Chen Z, Zhen H, Ma Y, Jie Z, Xiao L, Yang H, Wang J, Kristiansen K, Xu X, Jin L, Nie C, Krutmann J, Liu X, Wang J.	Microbiome	10.1186/s40168-020-00995-7	2021
Enzymology	Corynebacterium prosthetic joint infection.	Cazanave C, Greenwood-Quaintance KE, Hanssen AD, Patel R.	J Clin Microbiol	10.1128/jcm.06439-11	2012
Phylogeny	16S rRNA gene sequencing on a benchtop sequencer: accuracy for identification of clinically important bacteria.	Watts GS, Youens-Clark K, Slepian MJ, Wolk DM, Oshiro MM, Metzger GS, Dhingra D, Cranmer LD, Hurwitz BL.	J Appl Microbiol	10.1111/jam.13590	2017
Phylogeny	Metagenomic Approaches to Assess Bacteriophages in Various Environmental Niches.	Hayes S, Mahony J, Nauta A, van Sinderen D.	Viruses	10.3390/v9060127	2017
Genetics	Genomic and functional techniques to mine the microbiome for novel antimicrobials and antimicrobial resistance genes.	Adu-Oppong B, Gasparrini AJ, Dantas G.	Ann N Y Acad Sci	10.1111/nyas.13257	2017
Enzymology	Evaluation of the Bruker MALDI Biotyper for identification of Gram-positive rods: development of a diagnostic algorithm for the clinical laboratory.	Schulthess B, Bloemberg GV, Zbinden R, Bottger EC, Hombach M.	J Clin Microbiol	10.1128/jcm.02399-13	2014
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Phylogeny	Corynebacterium simulans sp. nov., a non-lipophilic, fermentative Corynebacterium.	Wattiau P, Janssens M, Wauters G	Int J Syst Evol Microbiol	10.1099/00207713-50-1-347	2000