Corynebacterium durum (IFO 16161, LMG 19045, CIP 105490)

Name: Corynebacterium durum (IFO 16161, LMG 19045, CIP 105490)
Creator: BacDive
License: http://creativecommons.org/licenses/by/4.0/

BacDive ID 3181

Type strain

Culture col. no. IFO 16161 LMG 19045 CIP 105490 CCM 4727 DSM 45333 4 more

NCBI tax ID(s) 61592

Special Collections DSMZ CCUG JCM CIP Literature strains

History DSMZ <- CCUG; CCUG 37331 <- P. Riegel, Univ. Loius Pasteur, Strasbourg, France JCM <-- CIP 105490 <-- CCUG 37331 <-- P. Riegel IBS G15036. CIP <- 1998, CCUG <- P. Riegel, Louis Pasteur Univ., Strasbourg, France

Links

Corynebacterium durum IFO 16161 is an aerobe, Gram-positive, rod-shaped bacterium that was isolated from human sputum.

Gram-positive rod-shaped aerobe genome sequence 16S sequence Bacteria

Name and taxonomic classification

SI-ID 12971

LMG 19045,CCUG 37331,CIP 105490,DSM 44351,IFO 16161,CCM 4727,JCM 11948,NBRC 16161,DSM 45333

@ref 20215

Last LPSN update 2026-05-29 08:25:39

Domain Bacteria

Phylum Actinomycetota

Class Actinomycetes

Order Mycobacteriales

Family Corynebacteriaceae

Genus Corynebacterium

Species Corynebacterium durum

Full scientific name Corynebacterium durum Riegel et al. 1997

BacDive ID	Other strains from **Corynebacterium durum** (4)	Type strain
151034	C. durum CCUG 43120
153811	C. durum CCUG 51244, KCCM 42201
156044	C. durum CCUG 60194 B
156706	C. durum CCUG 64264

Morphology

Cell morphology

@ref	Gram stain	Cell shape	Confidence
23179	positive	rod-shaped
118983	positive	rod-shaped
125439			96.511
125439	positive		95.174

Colony morphology

@ref	Colony size	Colony color	Incubation period
23179	0.5-1.0 mm	beige	3 days

Multimedia

@ref:	16295
multimedia content:	DSM_45333.jpg
multimedia.multimedia content:	https://www.dsmz.de/microorganisms/photos/DSM_45333.jpg
caption:	Medium 535 37°C
intellectual property rights:	© Leibniz-Institut DSMZ
manual_annotation:	1

Culture and growth conditions

Culture medium

@ref	Name	Medium link	Composition
16295	TRYPTICASE SOY BROTH AGAR (DSMZ Medium 535)	Medium recipe at MediaDive	Name: TRYPTICASE SOY BROTH AGAR (DSMZ Medium 535) Composition: Trypticase soy broth 30.0 g/l Agar 15.0 g/l Distilled water
16295	TRYPTICASE SOY BROTH AGAR+BLOOD (DSMZ Medium 535a)	Medium recipe at MediaDive	Name: TRYPTICASE SOY BROTH AGAR+BLOOD (DSMZ Medium 535a) Composition: None 50.0 g/l Trypticase soy broth 30.0 g/l Agar 15.0 g/l Distilled water
34040	MEDIUM 45 - for Columbia agar with sheep blood		Distilled water make up to (1000.000 ml);Columbia agar (39.000 g);Sheepblood (100.000 ml)
118983	CIP Medium 45	Medium recipe at CIP

Culture temp

@ref	Growth	Type	Temperature (°C)
16295	positive	growth	37
23179	positive	growth	37
34040	positive	growth	37
53611	positive	growth	37
67770	positive	growth	37
118983	positive	growth	25-41
118983	negative	growth	10
118983	negative	growth	15
118983	negative	growth	45

Physiology and metabolism

Oxygen tolerance

@ref	Oxygen tolerance	Confidence
23179	aerobe
53611	aerobe
118983	facultative anaerobe
125439	facultative anaerobe	92.855

Spore formation

@ref	Spore formation	Confidence
23179
125439		98.102

Halophily

@ref	Salt	Growth	Tested relation	Concentration
118983	NaCl	positive	growth	0-4 %
118983	NaCl		growth	6 %
118983	NaCl		growth	8 %
118983	NaCl		growth	10 %

Metabolite utilization

@ref	Chebi-ID	Metabolite	Utilization activity	Kind of utilization tested
68371	27613 ChEBI	amygdalin	-	builds acid from	from API 50CH acid
68371	17057 ChEBI	cellobiose	-	builds acid from	from API 50CH acid
118983	16947 ChEBI	citrate	-	carbon source
68371	17108 ChEBI	D-arabinose	-	builds acid from	from API 50CH acid
68371	18333 ChEBI	D-arabitol	-	builds acid from	from API 50CH acid
68371	15824 ChEBI	D-fructose	+	builds acid from	from API 50CH acid
68371	28847 ChEBI	D-fucose	-	builds acid from	from API 50CH acid
68371	12936 ChEBI	D-galactose	+	builds acid from	from API 50CH acid
68371	17634 ChEBI	D-glucose	+	builds acid from	from API 50CH acid
68371	62318 ChEBI	D-lyxose	-	builds acid from	from API 50CH acid
68379	16899 ChEBI	D-mannitol	-	fermentation	from API Coryne
68371	16899 ChEBI	D-mannitol	+	builds acid from	from API 50CH acid
68371	16024 ChEBI	D-mannose	+	builds acid from	from API 50CH acid
68379	16988 ChEBI	D-ribose	-	fermentation	from API Coryne
68371	17924 ChEBI	D-sorbitol	-	builds acid from	from API 50CH acid
68371	16443 ChEBI	D-tagatose	-	builds acid from	from API 50CH acid
68379	65327 ChEBI	D-xylose	-	fermentation	from API Coryne
68371	65327 ChEBI	D-xylose	-	builds acid from	from API 50CH acid
68371	17113 ChEBI	erythritol	-	builds acid from	from API 50CH acid
23179	4853 ChEBI	esculin	+/-	hydrolysis
68379	4853 ChEBI	esculin	+	hydrolysis	from API Coryne
118983	4853 ChEBI	esculin	-	hydrolysis
68371	4853 ChEBI	esculin	+	builds acid from	from API 50CH acid
23179	28757 ChEBI	fructose	+	builds acid from
68371	16813 ChEBI	galactitol	-	builds acid from	from API 50CH acid
23179	28260 ChEBI	galactose	+	builds acid from
23179	5291 ChEBI	gelatin	-	degradation
68379	5291 ChEBI	gelatin	-	hydrolysis	from API Coryne
68371	28066 ChEBI	gentiobiose	-	builds acid from	from API 50CH acid
68371	24265 ChEBI	gluconate	-	builds acid from	from API 50CH acid
23179	17234 ChEBI	glucose	+	builds acid from
68371	17754 ChEBI	glycerol	-	builds acid from	from API 50CH acid
23179	28087 ChEBI	glycogen	-	builds acid from
68379	28087 ChEBI	glycogen	-	fermentation	from API Coryne
68371	28087 ChEBI	glycogen	-	builds acid from	from API 50CH acid
118983	606565 ChEBI	hippurate	+	hydrolysis
68371	15443 ChEBI	inulin	-	builds acid from	from API 50CH acid
68371	30849 ChEBI	L-arabinose	-	builds acid from	from API 50CH acid
68371	18403 ChEBI	L-arabitol	-	builds acid from	from API 50CH acid
68371	18287 ChEBI	L-fucose	-	builds acid from	from API 50CH acid
68371	62345 ChEBI	L-rhamnose	-	builds acid from	from API 50CH acid
68371	17266 ChEBI	L-sorbose	-	builds acid from	from API 50CH acid
68371	65328 ChEBI	L-xylose	-	builds acid from	from API 50CH acid
23179	17716 ChEBI	lactose	-	builds acid from
68379	17716 ChEBI	lactose	-	fermentation	from API Coryne
68371	17716 ChEBI	lactose	-	builds acid from	from API 50CH acid
23179	17306 ChEBI	maltose	+	builds acid from
68379	17306 ChEBI	maltose	-	fermentation	from API Coryne
68371	17306 ChEBI	maltose	+	builds acid from	from API 50CH acid
23179	29864 ChEBI	mannitol	+	builds acid from
68371	6731 ChEBI	melezitose	-	builds acid from	from API 50CH acid
68371	28053 ChEBI	melibiose	-	builds acid from	from API 50CH acid
68371	320061 ChEBI	methyl alpha-D-glucopyranoside	-	builds acid from	from API 50CH acid
68371	43943 ChEBI	methyl alpha-D-mannoside	-	builds acid from	from API 50CH acid
68371	74863 ChEBI	methyl beta-D-xylopyranoside	-	builds acid from	from API 50CH acid
68371	17268 ChEBI	myo-inositol	-	builds acid from	from API 50CH acid
68371	59640 ChEBI	N-acetylglucosamine	-	builds acid from	from API 50CH acid
23179	17632 ChEBI	nitrate	+	reduction
68379	17632 ChEBI	nitrate	+	reduction	from API Coryne
118983	17632 ChEBI	nitrate	+	reduction
118983	17632 ChEBI	nitrate	+	respiration
118983	16301 ChEBI	nitrite	-	reduction
68371	0 ChEBI	Potassium 2-ketogluconate	-	builds acid from	from API 50CH acid
68371	16634 ChEBI	raffinose	-	builds acid from	from API 50CH acid
68371	15963 ChEBI	ribitol	-	builds acid from	from API 50CH acid
23179	33942 ChEBI	ribose	-	builds acid from
68371	17814 ChEBI	salicin	-	builds acid from	from API 50CH acid
68371	28017 ChEBI	starch	-	builds acid from	from API 50CH acid
23179	17992 ChEBI	sucrose	+	builds acid from
68371	17992 ChEBI	sucrose	+	builds acid from	from API 50CH acid
23179	27082 ChEBI	trehalose	-	builds acid from
68371	27082 ChEBI	trehalose	-	builds acid from	from API 50CH acid
68371	32528 ChEBI	turanose	-	builds acid from	from API 50CH acid
23179	18186 ChEBI	tyrosine	-	degradation
23179	16199 ChEBI	urea	+	degradation
68379	16199 ChEBI	urea	-	hydrolysis	from API Coryne
68371	17151 ChEBI	xylitol	-	builds acid from	from API 50CH acid
23179	18222 ChEBI	xylose	-	builds acid from

Antibiotic resistance

@ref	Metabolite	Is sensitive	Is resistant
118983	0129 (2,4-Diamino-6,7-di-iso-propylpteridine phosphate)

Metabolite production

@ref	Chebi-ID	Metabolite	Production
118983	35581 ChEBI	indole

Metabolite tests

@ref	Chebi-ID	Metabolite	Voges-proskauer-test	Methylred-test
118983	15688 ChEBI	acetoin	+
118983	17234 ChEBI	glucose		+

Enzymes

@ref	Value	Activity	Ec
23179	6-phospho-beta-galactosidase	-	3.2.1.85
68382	acid phosphatase	-	3.1.3.2	from API zym
118983	alcohol dehydrogenase	-	1.1.1.1
23179	alkaline phosphatase	-	3.1.3.1
68382	alkaline phosphatase	-	3.1.3.1	from API zym
68379	alkaline phosphatase	-	3.1.3.1	from API Coryne
68382	alpha-chymotrypsin	-	3.4.21.1	from API zym
68382	alpha-fucosidase	-	3.2.1.51	from API zym
68382	alpha-galactosidase	-	3.2.1.22	from API zym
23179	alpha-glucosidase	-	3.2.1.20
68382	alpha-glucosidase	-	3.2.1.20	from API zym
68379	alpha-glucosidase	-	3.2.1.20	from API Coryne
68382	alpha-mannosidase	-	3.2.1.24	from API zym
118983	amylase	+
68382	beta-galactosidase	-	3.2.1.23	from API zym
118983	beta-galactosidase	+	3.2.1.23
68379	beta-galactosidase	-	3.2.1.23	from API Coryne
68382	beta-glucosidase	-	3.2.1.21	from API zym
68379	beta-glucosidase	+	3.2.1.21	from API Coryne
23179	beta-glucuronidase	-	3.2.1.31
68382	beta-glucuronidase	-	3.2.1.31	from API zym
68379	beta-glucuronidase	-	3.2.1.31	from API Coryne
118983	caseinase	-	3.4.21.50
118983	catalase	+	1.11.1.6
68382	cystine arylamidase	-	3.4.11.3	from API zym
118983	DNase	-
118983	gamma-glutamyltransferase	+	2.3.2.2
118983	gelatinase	-
68379	gelatinase	-		from API Coryne
118983	lecithinase	-
68382	leucine arylamidase	-	3.4.11.1	from API zym
118983	lipase	-
68382	lipase (C 14)	-		from API zym
118983	lysine decarboxylase	-	4.1.1.18
23179	N-acetyl-beta-glucosaminidase	-	3.2.1.52
68382	N-acetyl-beta-glucosaminidase	-	3.2.1.52	from API zym
68379	N-acetyl-beta-glucosaminidase	-	3.2.1.52	from API Coryne
118983	ornithine decarboxylase	-	4.1.1.17
118983	oxidase	-
118983	phenylalanine ammonia-lyase	-	4.3.1.24
23179	pyrazinamidase	+	3.5.1.B15
68379	pyrazinamidase	-	3.5.1.B15	from API Coryne
23179	pyrrolidonyl arylamidase	-	3.4.19.3
68379	pyrrolidonyl arylamidase	-	3.4.19.3	from API Coryne
68382	trypsin	-	3.4.21.4	from API zym
118983	tryptophan deaminase	-
118983	tween esterase	-
118983	urease	+	3.5.1.5
68379	urease	-	3.5.1.5	from API Coryne
68382	valine arylamidase	-		from API zym

API coryne

@ref	Reduction of nitrateNIT	PYZ	PYRA	PAL	beta GUR	beta GAL	alpha GLU	beta NAG	ESC	URE	GEL	Control fermentationControl	GLU	RIB	XYL	MAN	MAL	LAC	SAC	GLYG	CAT
16295	+	-	-	-	-	-	-	-	+	-	-	-	+/-	-	-	-	-	-	+/-	-	not determinedn.d.

API zym

@ref	Control	Alkaline phosphatase	Esterase (C 4)	2-naphtyl caprylateEsterase Lipase (C 8)	Lipase (C 14)	L-leucyl-2-naphthylamideLeucine arylamidase	L-valyl-2-naphthylamideValine arylamidase	L-cystyl-2-naphthylamideCystine arylamidase	Trypsin	alpha- Chymotrypsin	Acid phosphatase	Naphthol-AS-BI-phosphateNaphthol-AS-BI-phosphohydrolase	alpha- Galactosidase	beta- Galactosidase	beta- Glucuronidase	alpha- Glucosidase	beta- Glucosidase	N-acetyl-beta- glucosaminidase	alpha- Mannosidase	alpha- Fucosidase
16295	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
118983	-	-	+	+	-	-	-	-	-	-	-	+	-	-	-	-	-	-	-	-

API 50CHac

@ref	ControlQ	GLY	ERY	DARA	LARA	RIB	DXYL	LXYL	ADO	MDX	GAL	GLU	FRU	MNE	SBE	RHA	DUL	INO	MAN	SOR	MDM	MDG	NAG	AMY	ARB	ESC	SAL	CEL	MAL	LAC	MEL	SAC	TRE	INU	MLZ	RAF	AMD	GLYG	XLT	GEN	TUR	LYX	TAG	DFUC	LFUC	DARL	LARL	GNT	2KG	5KG
118983	not determinedn.d.	-	-	-	-	+/-	-	-	-	-	+	+	+	+	-	-	-	-	+	-	-	-	-	-	+/-	+	-	-	+	-	-	+	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	+/-

API biotype100

@ref	ControlQ	D-glucose as carbon sourceGLU	D-fructose as carbon sourceFRU	D-galactose as carbon sourceGAL	D-trehalose as carbon sourceTRE	D-mannose as carbon sourceMNE	L-sorbose as carbon sourceSBE	D-melibiose as carbon sourceMEL	sucrose as carbon sourceSAC	D-raffinose as carbon sourceRAF	maltotriose as carbon sourceMTE	maltose as carbon sourceMAL	lactose as carbon sourceLAC	lactulose as carbon sourceLTE	1-O-methyl-beta-galactopyranoside as carbon sourceMbGa	1-O-methyl-alpha-galactopyranoside as carbon sourceMaGa	D-cellobiose as carbon sourceCEL	gentiobiose as carbon sourceGEN	1-O-methyl-beta-D-glucopyranoside as carbon sourceMbGu	esculin as carbon sourceESC	D-ribose as carbon sourceRIB	L-arabinose as carbon sourceARA	D-xylose as carbon sourceXYL	palatinose as carbon sourcePLE	L-rhamnose as carbon sourceRHA	L-fucose as carbon sourceFUC	D-melezitose as carbon sourceMLZ	D-arabitol as carbon sourceDARL	L-arabitol as carbon sourceLARL	xylitol as carbon sourceXLT	dulcitol as carbon sourceDUL	D-tagatose as carbon sourceTAG	glycerol as carbon sourceGLY	myo-inositol as carbon sourceINO	D-mannitol as carbon sourceMAN	maltitol as carbon sourceMTL	D-turanose as carbon sourceTUR	D-sorbitol as carbon sourceSOR	adonitol as carbon sourceADO	hydroxyquinoline-beta-glucuronide as carbon sourceHBG	D-lyxose as carbon sourceLYX	i-erythritol as carbon sourceERY	1-O-methyl-alpha-D-glucoside as carbon sourceMDG	3-O-methyl-D-glucose as carbon source3MDG	D-saccharate as carbon sourceSAT	mucate as carbon sourceMUC	L-tartrate as carbon sourceLTAT	D-tartrate as carbon sourceDTAT	meso-tartrate as carbon sourceMTAT	D-malate as carbon sourceDMLT	L-malate as carbon sourceLMLT	cis-aconitate as carbon sourceCATE	trans-aconitate as carbon sourceTATE	tricarballylate as carbon sourceTTE	citrate as carbon sourceCIT	D-glucuronate as carbon sourceGRT	D-galacturonate as carbon sourceGAT	2-ketogluconate as carbon source2KG	5-ketogluconate as carbon source5KG	tryptophan as carbon sourceTRY	N-acetyl-D-glucosamine as carbon sourceNAG	D-gluconate as carbon sourceGNT	phenylacetate as carbon sourcePAC	protocatechuate as carbon sourcePAT	4-hydroxybenzoate as carbon sourcepOBE	quinate as carbon sourceQAT	gentisate as carbon sourceGTE	3-hydroxybenzoate as carbon sourcemOBE	benzoate as carbon sourceBAT	3-phenylpropionate as carbon sourcePPAT	m-coumarate as carbon sourceCMT	trigonelline as carbon sourceTGE	betaine as carbon sourceBET	putrescine as carbon sourcePCE	4-aminobutyrate as carbon sourceABT	histamine as carbon sourceHIN	DL-lactate as carbon sourceLAT	caprate as carbon sourceCAP	caprylate as carbon sourceCYT	L-histidine as carbon sourceHIS	succinate as carbon sourceSUC	fumarate as carbon sourceFUM	glutarate as carbon sourceGRE	DL-glycerate as carbon sourceGYT	5-aminovalerate as carbon sourceAVT	ethanolamine as carbon sourceETN	tryptamine as carbon sourceTTN	D-glucosamine as carbon sourceGLN	itaconate as carbon sourceITA	3-hydroxybutyrate as carbon source3OBU	L-aspartate as carbon sourceAPT	L-glutamate as carbon sourceGTT	L-proline as carbon sourcePRO	D-alanine as carbon sourceDALA	L-alanine as carbon sourceLALA	L-serine as carbon sourceSER	malonate as carbon sourceMNT	propionate as carbon sourcePROP	L-tyrosine as carbon sourceTYR	2-ketoglutarate as carbon source2KT
118983	not determinedn.d.	+	+	+	-	+	-	-	+	-	+	+	-	-	-	-	-	-	+	-	+	-	-	-	-	-	-	-	-	-	-	-	-	-	+	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-

Isolation, sampling and environmental information

Isolation source categories

Cat1	Cat2	Cat3
#Host	#Human	-
#Host Body Product	#Fluids	#Sputum

Isolation

@ref	Sample type	Host species	Geographic location	Country	Country ISO 3 Code	Continent
16295	human sputum	Homo sapiens	Strasbourg	France	FRA	Europe
53611	Human sputum	Homo sapiens	Strasbourg	France	FRA	Europe
67770	Sputum of a patient	Homo sapiens	New Caledonia	French Overseas	FRA
118983	Human, Sputum	Homo sapiens	Strasbourg	France	FRA	Europe

Taxonmaps

69479

Global distribution of 16S sequence Z97069 (>99% sequence identity) for Corynebacterium durum subclade from Microbeatlas

Aquatic Samples	1504
Soil Samples	865
Animal Samples	58839
Plant Samples	361
Total Samples	61569

Interaction and safety

Risk assessment

@ref	Pathogenicity human	Biosafety level	Biosafety level comment
16295	yes, in single cases	1	Risk group (German classification) According to TRBA 466
118983		2	Risk group (French classification) According to TRBA 466

Sequence information

Genome sequences

@ref	Description	Assembly level	INSDC accession	BV-BRC accession	IMG accession	NCBI tax ID	Score
66792	Corynebacterium durum DSM 45333 Genome sequencing	complete			2623620526	61592	99.66
124043	ASM3040867v1 assembly for Corynebacterium durum DSM 45333	complete	GCA_030408675	61592.141	8030271416	61592	98.77
67770	ASM1341030v1 assembly for Corynebacterium durum DSM 45333	contig	GCA_013410305	61592.134	2856490523	61592	78.69
124043	ASM3952698v1 assembly for Corynebacterium durum JCM 11948	scaffold	GCA_039526985			61592	72.44

16S sequences

@ref	Description	Accession	Length	Database	NCBI tax ID
20218	Corynebacterium durum 16S ribosomal RNA gene, partial sequence	AY438053	419		61592
23179	Corynebacterium durum 16S ribosomal RNA	Z97069	1423		61592

GC content

@ref	GC-content (mol%)	Method
23179	55.0	high performance liquid chromatography (HPLC)
67770	55.4	capillary zone electrophoresis (CZE)

Genome-based predictions

Predictions

Predictions from Deep Learning for Genome Sequence Data. R package version 0.3.1 based on: ASM3040867v1 assembly for Corynebacterium durum DSM 45333
NCBI: GCA_030408675

@ref	Trait	Model	Prediction	Confidence in %	In training data
125439	oxygen_tolerance	BacteriaNetⓘ	facultative anaerobe	92.86	no
125439	gram_stain	BacteriaNetⓘ	positive	95.17	no
125439	motility	BacteriaNetⓘ	no	96.51	no
125439	spore_formation	BacteriaNetⓘ	no	98.10	no

Literature

Topic	Title	Authors	Journal	DOI	Year
Enzymology	Coryneform bacteria in throat cultures of healthy individuals.	von Graevenitz A, Punter-Streit V, Riegel P, Funke G.	J Clin Microbiol	10.1128/jcm.36.7.2087-2088.1998	1998
	A case of pneumonia caused by Corynebacterium durum mimicking Nocardia pneumonia in a patient with dermatomyositis.	Hara N, Higuchi T, Fujisaki M, Motoyama R, Yamada R, Yamaguchi R, Tochimoto A, Tanaka E, Kikuchi K, Ito A, Harigai M.	J Infect Chemother	10.1016/j.jiac.2025.102869	2025
	Key Bacterial Taxa Differences Associated with Polypharmacy in Elderly Patients.	Shahin B, Nadeem T, Khosla T, Adami GR.	Microorganisms	10.3390/microorganisms13081877	2025
	Corynebacterium durum and possibilities of its identification.	Vitkova P, Bechynkova O, Scharfen J, Buchta V.	Epidemiol Mikrobiol Imunol	10.61568/emi/11-6492/20250428/140417	2025
	The cutaneous microbiota and Nannizziomycosis in bearded dragons (Pogona vitticeps): Associations between infectious Nannizziopsis species and common bacterial pathogens.	Zapanta K, Kavanagh M, Keller K, Nguyen L, Rosenkrantz W, Krumbeck JA.	Vet Dermatol	10.1111/vde.13360	2025
	Oxidative tryptamine dimers from Corynebacterium durum directly target survivin to induce AIF-mediated apoptosis in cancer cells.	Kim S, Lee M, Kim NY, Kwon YS, Nam GS, Lee K, Kwon KM, Kim DK, Hwang IH.	Biomed Pharmacother	10.1016/j.biopha.2024.116335	2024
	Key Bacterial Taxa Differences Associated with Polypharmacy in Elderly Patients	Shahin B, Nadeem T, Khosla T, Adami G.	Microorganisms		2025
Phylogeny	The short-term impact of comprehensive caries treatment on the supragingival microbiome of severe early childhood caries.	Tian J, Zhao B, Wang J, Du W, Ma W, Xia B, Xu H, Chen T, He X, Qin M.	Int J Paediatr Dent	10.1111/ipd.13151	2024
Phylogeny	Altered oral microbiomes in patients with prolonged disorders of consciousness.	Xu M, He Z, Zhou J, Zhao J, Tian X, Cheng Q, Lin Y, Xin H, Mou C, Xue Q, Luo B.	J Oral Microbiol	10.1080/20002297.2025.2577220	2025
Genetics	Probiotics to reduce microbiota-related dental stains: A potential approach.	Yu JJ, Hernandez-Kapila Y, Wang CW.	J Dent Sci	10.1016/j.jds.2025.03.021	2025
	Gut microbiota and metabolic signatures of anxiety in ulcerative colitis: a cross-sectional study.	Ping Y, Zhao X, Lv L, Meng W, Meng Y, Ruan G, Cheng Y, Xiao Z, Tian Y, Chen M, Chen L, Yi A, Tang Z, Li N, Chen D, Wei Y.	Therap Adv Gastroenterol	10.1177/17562848251393419	2025
	Glycerol metabolism supports oral commensal interactions.	Treerat P, Anderson D, Giacaman RA, Merritt J, Kreth J.	ISME J	10.1038/s41396-023-01426-9	2023
	Microbiological Profiles of Patients with Acute Periprosthetic Joint Infection Undergoing Debridement, Antibiotics, Irrigation and Implant Retention (DAIR).	Zellner AA, Watzlawik N, Roos J, Hischebeth GTR, Molitor E, Franz A, Froschen FS.	Antibiotics (Basel)	10.3390/antibiotics14090873	2025
	Salivary Microbiome Profiling of HPV+ and HPV- Oropharyngeal Head and Neck Cancer Patients Undergoing Durvalumab Immunotherapy Suggests Prevotella melaninogenica and Veillonella atypica as Key Players: A Pilot Study.	Mougeot JL, Beckman M, Kooshki M, Neuberger J, Shukla K, Furdui C, Bahrani Mougeot F, Porosnicu M.	Cancers (Basel)	10.3390/cancers17030452	2025
Phylogeny	Gestational diabetes mellitus and gut microbiota: microbial signatures across different fetal birth weight outcomes and their impact on maternal and neonatal health.	Xia D, Wang H, Wang W.	BMC Pregnancy Childbirth	10.1186/s12884-025-08324-2	2025
	The impact of vaping behavior on functional changes within the subgingival microbiome.	Yang I, He X, Jeon J, Claussen H, Arthur R, Cushenan P, Weaver SR, Luo R, Black M, Shannahan J, Wright C.	Sci Rep	10.1038/s41598-025-17121-y	2025
Phylogeny	Microbial Biomarkers of Breast Tumor and Mastitis: Deciphering the Delicate Balance between Potentially "Evil" and "Benign" Alliances in Mammary Microbiomes.	Ma ZS.	Breast Care (Basel)	10.1159/000548037	2025
Phylogeny	The blood pressure lowering effect of beetroot juice is impaired in periodontitis and recovered after periodontal treatment.	Sanchez-Orozco NY, Rosier BT, Ruiz-Gutierrez A, Marquez-Sandoval F, Artacho A, Carrera-Quintanar L, Mira A.	NPJ Biofilms Microbiomes	10.1038/s41522-024-00622-5	2025
	Corynebacterial membrane vesicles disrupt cariogenic interkingdom assemblages.	Treerat P, Rozendal T, de Mattos C, Davis A, Helliwell E, Merritt J, Kreth J.	Appl Environ Microbiol	10.1128/aem.00885-24	2024
	Mild atopic dermatitis is characterized by increase in non-staphylococcus pathobionts and loss of specific species.	Delanghe L, De Boeck I, Van Malderen J, Allonsius CN, Van Rillaer T, Bron PA, Claes I, Hagendorens M, Lebeer S, Leysen J.	Sci Rep	10.1038/s41598-024-74513-2	2024
	Dental plaque microbiota profiles of children with caries-free and caries-active dentition.	Qudeimat MA, Alyahya A, Karched M, Behbehani J, Salako NO.	J Dent	10.1016/j.jdent.2020.103539	2021
	Supra- and Subgingival Microbiome in Gingivitis and Impact of Biofilm Control: A Comprehensive Review	Iniesta M, Vasconcelos V, Sanz M, Herrera D.	Antibiotics (Basel)		2024
	Oral microbiome diversity: The curious case of Corynebacterium sp. isolation.	Treerat P, McGuire B, Palmer E, Dahl EM, Karstens L, Merritt J, Kreth J.	Mol Oral Microbiol	10.1111/omi.12381	2022
	Enhanced dominance of nitrate-reducing bacteria using a combination of nitrate and erythritol in in vitro cultured oral biofilm.	Fujii A, Akatsu T, Souno H, Kawano S, Minegishi Y, Ota N.	J Oral Microbiol	10.1080/20002297.2025.2526069	2025
	Associations of Chronic Marijuana Use with Changes in Salivary Microbiome.	Panee J, Qin Y, Deng Y.	Microorganisms	10.3390/microorganisms12112244	2024
	Oral Microbiome and CPT1A Function in Fatty Acid Metabolism in Oral Cancer.	Praveen Z, Choi SW, Lee JH, Park JY, Oh HJ, Kwon IJ, Park JH, Kim MK.	Int J Mol Sci	10.3390/ijms252010890	2024
	Microbiome dysbiosis in spinal pathology: Mechanisms, evidence, and research limitations	Rashid M, Pereira H, Alissa A, Keraidi S, Wipf N, Sowa A, McDonnell J, Darwish S, Butler J.	Brain Spine		2025
	Microbiome variability and role of Candida albicans in site-specific dental plaques in orthodontic adolescent patients with white spot lesions.	Yang H, Gao H, Xie X, Wang H, Li X, Qiao Q, Ma Y, Bai Y.	J Oral Microbiol	10.1080/20002297.2025.2522421	2025
	Dental biofilm serves as an ecological reservoir of acidogenic pathobionts in head and neck cancer patients with radiotherapy-related caries.	Bruno JS, Heidrich V, Restini FCF, Alves TMMT, Miranda-Silva W, Knebel FH, Coser EM, Inoue LT, Asprino PF, Camargo AA, Fregnani ER.	mSphere	10.1128/msphere.00257-25	2025
Metabolism	The prebiotic effect of CPP-ACP sugar-free chewing gum.	Fernando JR, Butler CA, Adams GG, Mitchell HL, Dashper SG, Escobar K, Hoffmann B, Shen P, Walker GD, Yuan Y, Reynolds C, Reynolds EC.	J Dent	10.1016/j.jdent.2019.103225	2019
	Modulating oral microbiota ameliorates hypobaric hypoxia-induced anxiety- and depression-like behaviors in mice.	Chang WY, Qin QZ, Li XT, Wang JJ, Chen Y, Ruan HQ, Qu YN, Jiang XX, He HX.	World J Psychiatry	10.5498/wjp.v15.i6.104809	2025
	Perinatal factors influencing the earliest establishment of the infant microbiome.	Linehan K, Healy K, Hurley E, O'Shea CA, Ryan CA, Ross RP, Stanton C, Dempsey EM.	Microbiome Res Rep	10.20517/mrr.2024.92	2025
	Alloprevotella rava isolated from a mixed infection of an elderly patient with chronic mandibular osteomyelitis mimicking oral squamous cell carcinoma.	Ulger Toprak N, Duman N, Sacak B, Ozkan MC, Sayin E, Mulazimoglu L, Soyletir G.	New Microbes New Infect	10.1016/j.nmni.2021.100880	2021
Genetics	Linking periodontitis with 20 cancers, emphasis on oropharyngeal cancer: a Mendelian randomization analysis.	Xiong J, Liu H, Li C, Li Y, Feng J.	Sci Rep	10.1038/s41598-024-63447-4	2024
	Randomized Controlled Study to Evaluate Microbial Ecological Effects of CPP-ACP and Cranberry on Dental Plaque.	Philip N, Leishman SJ, Bandara HMHN, Healey DL, Walsh LJ.	JDR Clin Trans Res	10.1177/2380084419859871	2020
	Supragingival microbiota, cytokines, and proteins in individuals with different trajectories in experimental gingivitis.	Lundtorp-Olsen C, Nygaard N, Massarenti L, Constancias F, Damgaard C, Kahraman Gursoy U, van Splunter A, Bikker FJ, Gursoy M, Gursoy M, Markvart M, Belstrom D.	J Oral Microbiol	10.1080/20002297.2024.2372861	2024
	Oral microbial dysbiosis in patients with oral cavity cancers.	Unlu O, Demirci M, Paksoy T, Eden AB, Tansuker HD, Dalmizrak A, Aktan C, Senel F, Sunter AV, Yigit O, Cakir BO, Kantarci A.	Clin Oral Investig	10.1007/s00784-024-05770-8	2024
	Linking Microbiota Profiles to Disease Characterization in Common Variable Immunodeficiency: The Case of Granulomatous-Lymphocytic Interstitial Lung Disease.	Cabanero-Navalon MD, Carda-Dieguez M, Moral Moral P, Mira A, Balastegui-Martin H, Salavert-Lleti M, Garcia-Bustos V.	Biomedicines	10.3390/biomedicines12102239	2024
	The effect of physical and psychological stress on the oral microbiome.	Stoy S, McMillan A, Ericsson AC, Brooks AE.	Front Psychol	10.3389/fpsyg.2023.1166168	2023
Metabolism	Metabolites Produced by the Oral Commensal Bacterium Corynebacterium durum Extend the Lifespan of Caenorhabditis elegans via SIR-2.1 Overexpression.	Kim JH, Bang IH, Noh YJ, Kim DK, Bae EJ, Hwang IH.	Int J Mol Sci	10.3390/ijms21062212	2020
	Oral biofilm composition and phenotype in caries-active and caries-free children.	Boisen G, Brogardh-Roth S, Neilands J, Mira A, Carda-Dieguez M, Davies JR.	Front Oral Health	10.3389/froh.2024.1475361	2024
	Staphylococcus aureus/Staphylococcus epidermidis from skin microbiota are balanced by Pomegranate peel extract: An eco-sustainable approach.	D'Arcangelo S, Di Fermo P, Diban F, Ferrone V, D'Ercole S, Di Giulio M, Di Lodovico S.	PLoS One	10.1371/journal.pone.0308211	2024
Transcriptome	Impact of surface characteristics on the peri-implant microbiome in health and disease.	Sinjab K, Sawant S, Ou A, Fenno JC, Wang HL, Kumar P.	J Periodontol	10.1002/jper.23-0205	2024
	Relationship between the subgingival microbiome and menopausal hormone therapy use: The Buffalo OsteoPerio study.	Soliman AI, LaMonte MJ, Hovey KM, McSkimming DI, Andrews CA, Diaz PI, Buck MJ, Sun Y, Millen AE, Wactawski-Wende J.	J Periodontol	10.1002/jper.22-0027	2022
	Microbiome of Saliva and Plaque in Children According to Age and Dental Caries Experience.	Lee E, Park S, Um S, Kim S, Lee J, Jang J, Jeong HO, Shin J, Kang J, Lee S, Jeong T.	Diagnostics (Basel)	10.3390/diagnostics11081324	2021
Phylogeny	New Insights into Mucosa-Associated Microbiota in Paired Tumor and Non-Tumor Adjacent Mucosal Tissues in Colorectal Cancer Patients.	Gonzalez A, Fullaondo A, Navarro D, Rodriguez J, Tirnauca C, Odriozola A.	Cancers (Basel)	10.3390/cancers16234008	2024
	Extensive microbiological respiratory tract specimen characterization in critically ill COVID-19 patients.	Thomsen K, Pedersen HP, Iversen S, Wiese L, Fuursted K, Nielsen HV, Christensen JJE, Nielsen XC.	APMIS	10.1111/apm.13143	2021
	qPCR assay optimisation for a clinical study comparing oral health risk in Rett syndrome.	Lai YYL, Downs J, Leishman S, Leonard HM, Walsh LJ, Zafar S.	Eur Arch Paediatr Dent	10.1007/s40368-024-00912-8	2024
	Supragingival microbiome variations and the influence of Candida albicans in adolescent orthodontic patients with gingivitis.	Yang H, Ma Y, Gao H, Xie X, Wang H, Li X, Bai Y.	J Oral Microbiol	10.1080/20002297.2024.2366056	2024
	Periodontal pathogens and obesity in the context of cardiovascular risks across age groups.	Leonov G, Varaeva Y, Livantsova E, Vasilyev A, Vladimirskaya O, Korotkova T, Nikityuk D, Starodubova A.	Front Oral Health	10.3389/froh.2024.1488833	2024
	Social networking at the microbiome-host interface.	Lamont RJ, Hajishengallis G, Koo H.	Infect Immun	10.1128/iai.00124-23	2023
Metabolism	Subgingival Microbiome and Specialized Pro-Resolving Lipid Mediator Pathway Profiles Are Correlated in Periodontal Inflammation.	Lee CT, Li R, Zhu L, Tribble GD, Zheng WJ, Ferguson B, Maddipati KR, Angelov N, Van Dyke TE.	Front Immunol	10.3389/fimmu.2021.691216	2021
Phylogeny	Nasal, dermal, oral and indoor dust microbe and their interrelationship in children with allergic rhinitis.	Tang H, Du S, Niu Z, Zhang D, Tang Z, Chen H, Chen Z, Zhang M, Xu Y, Sun Y, Fu X, Norback D, Shao J, Zhao Z.	BMC Microbiol	10.1186/s12866-024-03668-9	2024
	Differential Response of Oral Mucosal and Gingival Cells to Corynebacterium durum, Streptococcus sanguinis, and Porphyromonas gingivalis Multispecies Biofilms.	Redanz U, Redanz S, Treerat P, Prakasam S, Lin LJ, Merritt J, Kreth J.	Front Cell Infect Microbiol	10.3389/fcimb.2021.686479	2021
Phylogeny	Periodontal dysbiosis associates with reduced CSF Abeta42 in cognitively normal elderly.	Kamer AR, Pushalkar S, Gulivindala D, Butler T, Li Y, Annam KRC, Glodzik L, Ballman KV, Corby PM, Blennow K, Zetterberg H, Saxena D, de Leon MJ.	Alzheimers Dement (Amst)	10.1002/dad2.12172	2021
	Phenylacetic acid, an anti-vaginitis metabolite produced by the vaginal symbiotic bacterium Chryseobacterium gleum.	Kwon KM, Kim EH, Sim KH, Lee YJ, Kang EJ, Han KH, Jin JS, Kim DK, Ahn JH, Hwang IH.	Sci Rep	10.1038/s41598-024-62947-7	2024
	HIV infection and exposure is associated with increased cariogenic taxa, reduced taxonomic turnover, and homogenized spatial differentiation for the supragingival microbiome.	Mann AE, Aumend C, Crull S, O'Connell LM, Osagie E, Akhigbe P, Obuekwe O, Omoigberale A, Rowe M, Blouin T, Soule A, Kelly C, DOMHaIN Study Team, Burne RA, Coker MO, Richards VP.	Microbiome	10.1186/s40168-025-02123-9	2025
Genetics	Comparison of the oral microbial composition between healthy individuals and periodontitis patients in different oral sampling sites using 16S metagenome profiling.	Kim YT, Jeong J, Mun S, Yun K, Han K, Jeong SN.	J Periodontal Implant Sci	10.5051/jpis.2200680034	2022
Metabolism	A selective medium for the isolation of Corynebacterium species in oral cavities.	Tsuzukibashi O, Uchibori S, Shinozaki-Kuwahara N, Kobayashi T, Takada K, Hirasawa M.	J Microbiol Methods	10.1016/j.mimet.2014.06.005	2014
	Immunostimulatory effects of Streptococcus sanguinis extracellular membrane vesicles protect oral gingival epithelial cells from periodontal pathobiont damage.	Helliwell E, Rauch I, Nice T, Merritt J, Kreth J.	Infect Immun	10.1128/iai.00535-24	2025
	Gut microbiome influences efficacy of Endostatin combined with PD-1 blockade against colorectal cancer.	Xu J, Tian Y, Zhao B, Hu D, Wu S, Ma J, Yang L.	Mol Biomed	10.1186/s43556-024-00200-3	2024
	The inconsistent pathogenesis of endometriosis and adenomyosis: insights from endometrial metabolome and microbiome.	Li C, Xu X, Zhao X, Du B.	mSystems	10.1128/msystems.00202-25	2025
	Temperature influences commensal-pathogen dynamics in a nasal epithelial cell co-culture model.	Huffines JT, Boone RL, Kiedrowski MR.	mSphere	10.1128/msphere.00589-23	2024
	Molecular commensalism-how to investigate underappreciated health-associated polymicrobial communities.	Labossiere A, Ramsey M, Merritt J, Kreth J.	mBio	10.1128/mbio.01342-23	2023
	Oral Microbiome Is Associated With Incident Hypertension Among Postmenopausal Women.	LaMonte MJ, Gordon JH, Diaz-Moreno P, Andrews CA, Shimbo D, Hovey KM, Buck MJ, Wactawski-Wende J.	J Am Heart Assoc	10.1161/jaha.121.021930	2022
	Bacterial Composition and Metabolomics of Dental Plaque From Adolescents.	Havsed K, Stensson M, Jansson H, Carda-Dieguez M, Pedersen A, Neilands J, Svensater G, Mira A.	Front Cell Infect Microbiol	10.3389/fcimb.2021.716493	2021
	A randomized controlled trial to evaluate the effectiveness of a novel mouth rinse in patients with gingivitis.	Newman BA, Rosebrough CN, Tamashiro RA, Dias Ribeiro AP, Whitlock JA, Sidhu G, Aukhil I, Porral DY, Progulske-Fox A, Myntti MF, Wang GP.	BMC Oral Health	10.1186/s12903-022-02518-2	2022
	Machine Learning Approach Identified Multi-Platform Factors for Caries Prediction in Child-Mother Dyads.	Wu TT, Xiao J, Sohn MB, Fiscella KA, Gilbert C, Grier A, Gill AL, Gill SR.	Front Cell Infect Microbiol	10.3389/fcimb.2021.727630	2021
Phenotype	Upper respiratory tract microbiota is associated with small airway function and asthma severity.	Li Y, Zou C, Li J, Wang W, Guo Y, Zhao L, Jiang C, Zhao P, An X.	BMC Microbiol	10.1186/s12866-023-02757-5	2023
	Analysis of ileostomy stool samples reveals dysbiosis in patients with high-output stomas.	Matsuzawa H, Munakata S, Kawai M, Sugimoto K, Kamiyama H, Takahashi M, Kojima Y, Sakamoto K.	Biosci Microbiota Food Health	10.12938/bmfh.2020-062	2021
	Growth Inhibitory Effects of Antimicrobial Natural Products against Cariogenic and Health-Associated Oral Bacterial Species.	Philip N, Leishman S, Bandara H, Walsh L.	Oral Health Prev Dent	10.3290/j.ohpd.a44307	2020
	Environmental influences on Streptococcus sanguinis membrane vesicle biogenesis.	Helliwell E, Choi D, Merritt J, Kreth J.	ISME J	10.1038/s41396-023-01456-3	2023
	Suspension of oral hygiene practices highlights key bacterial shifts in saliva, tongue, and tooth plaque during gingival inflammation and resolution.	Hall MW, Wellappuli NC, Huang RC, Wu K, Lam DK, Glogauer M, Beiko RG, Senadheera DB.	ISME Commun	10.1038/s43705-023-00229-5	2023
Phylogeny	The oral bacteriomes of patients with allergic rhinitis and asthma differ from that of healthy controls.	Perez-Losada M, Castro-Nallar E, Laerte Boechat J, Delgado L, Azenha Rama T, Berrios-Farias V, Oliveira M.	Front Microbiol	10.3389/fmicb.2023.1197135	2023
	Microbiome profiles of non-responding and responding paired periodontitis sites within the same participants following non-surgical treatment.	Byrne SJ, Chang D, Adams GG, Butler CA, Reynolds EC, Darby IB, Dashper SG.	J Oral Microbiol	10.1080/20002297.2022.2043595	2022
	Unique microbial landscape in the human oropharynx during different types of acute respiratory tract infections.	Li H, Wu X, Zeng H, Chang B, Cui Y, Zhang J, Wang R, Ding T.	Microbiome	10.1186/s40168-023-01597-9	2023
	The Use of a Diode Laser for Removal of Microorganisms from the Surfaces of Zirconia and Porcelain Applied to Superstructure Dental Implants.	Wawrzyk A, Lobacz M, Adamczuk A, Sofinska-Chmiel W, Wilczynski S, Rahnama M.	Microorganisms	10.3390/microorganisms9112359	2021
Phylogeny	Association of gestational diabetes mellitus with changes in gut microbiota composition at the species level.	Chen F, Gan Y, Li Y, He W, Wu W, Wang K, Li Q.	BMC Microbiol	10.1186/s12866-021-02207-0	2021
	Vesicle-enriched secretomes alter bacterial competitive abilities and are drivers of evolution in microbial communities.	Warsi OM, Gedda L, Edwards K, Andersson DI.	FEMS Microbiol Ecol	10.1093/femsec/fiad141	2023
	Airway microbiota and immune mediator relationships differ in obesity and asthma.	Kozik AJ, Begley LA, Lugogo N, Baptist A, Erb-Downward J, Opron K, Huang YJ.	J Allergy Clin Immunol	10.1016/j.jaci.2022.11.024	2023
	Untargeted metabolomics of saliva in caries-active and caries-free children in the mixed dentition.	Li Y, Yang Z, Cai T, Jiang D, Luo J, Zhou Z.	Front Cell Infect Microbiol	10.3389/fcimb.2023.1104295	2023
	Characterization of the Oral Microbiome in Wearers of Fixed and Removable Implant or Non-Implant-Supported Prostheses in Healthy and Pathological Oral Conditions: A Narrative Review.	D'Ambrosio F, Santella B, Di Palo MP, Giordano F, Lo Giudice R.	Microorganisms	10.3390/microorganisms11041041	2023
Phylogeny	Candida albicans enriched in orthodontic derived white spot lesions and shaped focal supragingival bacteriome.	Yang H, Ma Y, Xie X, Wang H, Li X, Fang D, Bai Y.	Front Microbiol	10.3389/fmicb.2023.1084850	2023
	Valid and accepted novel bacterial taxa derived from human clinical specimens and taxonomic revisions published in 2022.	Munson E, Carella A, Carroll KC.	J Clin Microbiol	10.1128/jcm.00838-23	2023
Metabolism	Glycerol metabolism contributes to competition by oral streptococci through production of hydrogen peroxide.	Taylor ZA, Chen P, Noeparvar P, Pham DN, Walker AR, Kitten T, Zeng L.	J Bacteriol	10.1128/jb.00227-24	2024
Phylogeny	Streptococcus mutans-associated bacteria in dental plaque of severe early childhood caries.	Zhang Y, Fang J, Yang J, Gao X, Dong L, Zheng X, Sun L, Xia B, Zhao N, Ma Z, Wang Y.	J Oral Microbiol	10.1080/20002297.2022.2046309	2022
	Investigating the human jejunal microbiota.	Villmones HC, Svanevik M, Ulvestad E, Stenstad T, Anthonisen IL, Nygaard RM, Dyrhovden R, Kommedal O.	Sci Rep	10.1038/s41598-022-05723-9	2022
	A Single Dose of Nitrate Increases Resilience Against Acidification Derived From Sugar Fermentation by the Oral Microbiome.	Rosier BT, Palazon C, Garcia-Esteban S, Artacho A, Galiana A, Mira A.	Front Cell Infect Microbiol	10.3389/fcimb.2021.692883	2021
Phylogeny	Role of Williamsia and Segniliparus in human infections with the approach taxonomy, cultivation, and identification methods.	Fatahi-Bafghi M.	Ann Clin Microbiol Antimicrob	10.1186/s12941-021-00416-z	2021
	Smartphones as an Ecological Niche of Microorganisms: Microbial Activities, Assembly, and Opportunistic Pathogens.	He J, Shen X, Zhang N, Sun C, Shao Y.	Microbiol Spectr	10.1128/spectrum.01508-22	2022
	Comparison of sampling methods in assessing the microbiome from patients with ulcerative colitis.	Kim D, Jung JY, Oh HS, Jee SR, Park SJ, Lee SH, Yoon JS, Yu SJ, Yoon IC, Lee HS.	BMC Gastroenterol	10.1186/s12876-021-01975-3	2021
	Dysbiosis of Oral Microbiota and Metabolite Profiles Associated with Type 2 Diabetes Mellitus.	Li Y, Qian F, Cheng X, Wang D, Wang Y, Pan Y, Chen L, Wang W, Tian Y.	Microbiol Spectr	10.1128/spectrum.03796-22	2023
	Multimodal Data Integration Reveals Mode of Delivery and Snack Consumption Outrank Salivary Microbiome in Association With Caries Outcome in Thai Children.	Wu TT, Xiao J, Manning S, Saraithong P, Pattanaporn K, Paster BJ, Chen T, Vasani S, Gilbert C, Zeng Y, Li Y.	Front Cell Infect Microbiol	10.3389/fcimb.2022.881899	2022
	Immune status, and not HIV infection or exposure, drives the development of the oral microbiota.	Coker MO, Mongodin EF, El-Kamary SS, Akhigbe P, Obuekwe O, Omoigberale A, Langenberg P, Enwonwu C, Hittle L, Blattner WA, Charurat M.	Sci Rep	10.1038/s41598-020-67487-4	2020
	Subgingival microbiota in a population with and without cognitive dysfunction.	Holmer J, Aho V, Eriksdotter M, Paulin L, Pietiainen M, Auvinen P, Schultzberg M, Pussinen PJ, Buhlin K.	J Oral Microbiol	10.1080/20002297.2020.1854552	2021
	Corncob structures in dental plaque reveal microhabitat taxon specificity.	Morillo-Lopez V, Sjaarda A, Islam I, Borisy GG, Mark Welch JL.	Microbiome	10.1186/s40168-022-01323-x	2022
	Site- and Time-Dependent Compositional Shifts in Oral Microbiota Communities.	Esberg A, Eriksson L, Johansson I.	Front Oral Health	10.3389/froh.2022.826996	2022
	Epidemiological and Microbiome Characterization of Black Tooth Stain in Preschool Children.	Zhang Y, Yu R, Zhan JY, Cao GZ, Feng XP, Chen X.	Front Pediatr	10.3389/fped.2022.751361	2022
Genetics	Investigating the demographic history of Japan using ancient oral microbiota.	Eisenhofer R, Kanzawa-Kiriyama H, Shinoda KI, Weyrich LS.	Philos Trans R Soc Lond B Biol Sci	10.1098/rstb.2019.0578	2020
	The Use of the Diode Laser against the Microbiome on Composites Closing the Screw Access Hall (Sah) in the Reconstruction of Dental Implants: Ex Vivo Studies.	Wawrzyk A, Rahnama M, Sofinska-Chmiel W, Wilczynski S, Lobacz M.	Int J Environ Res Public Health	10.3390/ijerph19127494	2022
Pathogenicity	From Mouth to Muscle: Exploring the Potential Relationship between the Oral Microbiome and Cancer-Related Cachexia.	Raman SR, Liu C, Herremans KM, Riner AN, Vudatha V, Freudenberger DC, McKinley KL, Triplett EW, Trevino JG.	Microorganisms	10.3390/microorganisms10112291	2022
Transcriptome	The Colorectal Cancer Gut Environment Regulates Activity of the Microbiome and Promotes the Multidrug Resistant Phenotype of ESKAPE and Other Pathogens.	Lamaudiere MTF, Arasaradnam R, Weedall GD, Morozov IY.	mSphere	10.1128/msphere.00626-22	2023
	Differential network analysis of oral microbiome metatranscriptomes identifies community scale metabolic restructuring in dental caries.	Espinoza JL, Torralba M, Leong P, Saffery R, Bockmann M, Kuelbs C, Singh S, Hughes T, Craig JM, Nelson KE, Dupont CL.	PNAS Nexus	10.1093/pnasnexus/pgac239	2022
	Characterization and Analysis of the Skin Microbiota in Acne: Impact of Systemic Antibiotics.	Park SY, Kim HS, Lee SH, Kim S.	J Clin Med	10.3390/jcm9010168	2020
Phylogeny	Heritability of Oral Microbiota and Immune Responses to Oral Bacteria.	Esberg A, Haworth S, Kuja-Halkola R, Magnusson PKE, Johansson I.	Microorganisms	10.3390/microorganisms8081126	2020
	Bacterial diversity and functional analysis of severe early childhood caries and recurrence in India.	Kalpana B, Prabhu P, Bhat AH, Senthilkumar A, Arun RP, Asokan S, Gunthe SS, Verma RS.	Sci Rep	10.1038/s41598-020-78057-z	2020
	Amplicon-based microbiome study highlights the loss of diversity and the establishment of a set of species in patients with dentin caries.	Wolff D, Frese C, Schoilew K, Dalpke A, Wolff B, Boutin S.	PLoS One	10.1371/journal.pone.0219714	2019
	43-Year Temporal Trends in Immune Response to Oral Bacteria in a Swedish Population.	Esberg A, Johansson A, Claesson R, Johansson I.	Pathogens	10.3390/pathogens9070544	2020
	Characterization of Supragingival Plaque and Oral Swab Microbiomes in Children With Severe Early Childhood Caries.	de Jesus VC, Khan MW, Mittermuller BA, Duan K, Hu P, Schroth RJ, Chelikani P.	Front Microbiol	10.3389/fmicb.2021.683685	2021
	Synergism between Corynebacterium and Streptococcus sanguinis reveals new interactions between oral commensals.	Treerat P, Redanz U, Redanz S, Giacaman RA, Merritt J, Kreth J.	ISME J	10.1038/s41396-020-0598-2	2020
	Association between the nasopharyngeal microbiome and metabolome in patients with COVID-19.	Liu J, Liu S, Zhang Z, Lee X, Wu W, Huang Z, Lei Z, Xu W, Chen D, Wu X, Guo Y, Peng L, Lin B, Chong Y, Mou X, Shi M, Lan P, Chen T, Zhao W, Gao Z.	Synth Syst Biotechnol	10.1016/j.synbio.2021.06.002	2021
	Genomic ancestry, diet and microbiomes of Upper Palaeolithic hunter-gatherers from San Teodoro cave.	Scorrano G, Nielsen SH, Vetro DL, Sawafuji R, Mackie M, Margaryan A, Fotakis AK, Martinez-Labarga C, Fabbri PF, Allentoft ME, Carra M, Martini F, Rickards O, Olsen JV, Pedersen MW, Cappellini E, Sikora M.	Commun Biol	10.1038/s42003-022-04190-2	2022
	Geographic Variation Did Not Affect the Predictive Power of Salivary Microbiota for Caries in Children With Mixed Dentition.	Li S, Huang S, Guo Y, Zhang Y, Zhang L, Li F, Tan K, Lu J, Chen Z, Guo Q, Tang Y, Teng F, Yang F.	Front Cell Infect Microbiol	10.3389/fcimb.2021.680288	2021
	Arginine Metabolism in Supragingival Oral Biofilms as a Potential Predictor of Caries Risk.	Nascimento MM, Alvarez AJ, Huang X, Hanway S, Perry S, Luce A, Richards VP, Burne RA.	JDR Clin Trans Res	10.1177/2380084419834234	2019
Genetics	Nitrite Generating and Depleting Capacity of the Oral Microbiome and Cardiometabolic Risk: Results from ORIGINS.	Goh CE, Bohn B, Marotz C, Molinsky R, Roy S, Roy S, Paster BJ, Chen CY, Rosenbaum M, Yuzefpolskaya M, Colombo PC, Desvarieux M, Papapanou PN, Jacobs DR, Knight R, Demmer RT.	J Am Heart Assoc	10.1161/jaha.121.023038	2022
Phylogeny	Association of exacerbation phenotype with the sputum microbiome in chronic obstructive pulmonary disease patients during the clinically stable state.	Yang CY, Li SW, Chin CY, Hsu CW, Lee CC, Yeh YM, Wu KA.	J Transl Med	10.1186/s12967-021-02788-4	2021
	Corynebacterium matruchotii Demography and Adhesion Determinants in the Oral Cavity of Healthy Individuals.	Esberg A, Barone A, Eriksson L, Lif Holgerson P, Teneberg S, Johansson I.	Microorganisms	10.3390/microorganisms8111780	2020
	Variant of the lactase LCT gene explains association between milk intake and incident type 2 diabetes.	Luo K, Chen GC, Zhang Y, Moon JY, Xing J, Peters BA, Usyk M, Wang Z, Hu G, Li J, Selvin E, Selvin E, Rebholz CM, Wang T, Isasi CR, Yu B, Knight R, Boerwinkle E, Burk RD, Kaplan RC, Qi Q.	Nat Metab	10.1038/s42255-023-00961-1	2024
Enzymology	Is the Oral Microbiome Associated with Blood Pressure in Older Women?	Gordon JH, LaMonte MJ, Genco RJ, Zhao J, Li L, Hovey KM, Tsompana M, Buck MJ, Andrews CA, Mcskimming DI, Zheng W, Sun Y, Wactawski-Wende J.	High Blood Press Cardiovasc Prev	10.1007/s40292-019-00322-8	2019
Enzymology	Oral Microbiome Composition Reflects Prospective Risk for Esophageal Cancers.	Peters BA, Wu J, Pei Z, Yang L, Purdue MP, Freedman ND, Jacobs EJ, Gapstur SM, Hayes RB, Ahn J.	Cancer Res	10.1158/0008-5472.can-17-1296	2017
Phylogeny	Maturation of the Oral Microbiome in Caries-Free Toddlers: A Longitudinal Study.	Kahharova D, Brandt BW, Buijs MJ, Peters M, Jackson R, Eckert G, Katz B, Keels MA, Levy SM, Fontana M, Zaura E.	J Dent Res	10.1177/0022034519889015	2020
	Subgingival microbiome of rheumatoid arthritis patients in relation to their disease status and periodontal health.	Beyer K, Zaura E, Brandt BW, Buijs MJ, Brun JG, Crielaard W, Bolstad AI.	PLoS One	10.1371/journal.pone.0202278	2018
	Identification of Specific Oral and Gut Pathogens in Full Thickness Colon of Colitis Patients: Implications for Colon Motility.	Dinakaran V, Mandape SN, Shuba K, Pratap S, Sakhare SS, Tabatabai MA, Smoot DT, Farmer-Dixon CM, Kesavalu LN, Adunyah SE, Southerland JH, Gangula PR.	Front Microbiol	10.3389/fmicb.2018.03220	2018
	Rapid change of fecal microbiome and disappearance of Clostridium difficile in a colonized infant after transition from breast milk to cow milk.	Davis MY, Zhang H, Brannan LE, Carman RJ, Boone JH.	Microbiome	10.1186/s40168-016-0198-6	2016
	Electronic Cigarette Aerosol Modulates the Oral Microbiome and Increases Risk of Infection.	Pushalkar S, Paul B, Li Q, Yang J, Vasconcelos R, Makwana S, Gonzalez JM, Shah S, Xie C, Janal MN, Queiroz E, Bederoff M, Leinwand J, Solarewicz J, Xu F, Aboseria E, Guo Y, Aguallo D, Gomez C, Kamer A, Shelley D, Aphinyanaphongs Y, Barber C, Gordon T, Corby P, Li X, Saxena D.	iScience	10.1016/j.isci.2020.100884	2020
	Exploration of Nitrate Reductase Metabolic Pathway in Corynebacterium pseudotuberculosis.	Almeida S, Sousa C, Abreu V, Diniz C, Dorneles EM, Lage AP, Barh D, Azevedo V.	Int J Genomics	10.1155/2017/9481756	2017
	Salivary microbiota and metabolome associated with celiac disease.	Francavilla R, Ercolini D, Piccolo M, Vannini L, Siragusa S, De Filippis F, De Pasquale I, Di Cagno R, Di Toma M, Gozzi G, Serrazanetti DI, De Angelis M, Gobbetti M.	Appl Environ Microbiol	10.1128/aem.00362-14	2014
	Next-generation sequencing analysis reveals high bacterial diversity in wild venomous and non-venomous snakes from India.	Krishnankutty SP, Muraleedharan M, Perumal RC, Michael S, Benny J, Balan B, Kumar P, Manazhi J, Kumar BD, Santhosh S, Thomas G, Gupta R, Zachariah A.	J Venom Anim Toxins Incl Trop Dis	10.1186/s40409-018-0181-8	2018
	Integrated gut virome and bacteriome dynamics in COVID-19 patients.	Cao J, Wang C, Zhang Y, Lei G, Xu K, Zhao N, Lu J, Meng F, Yu L, Yan J, Bai C, Zhang S, Zhang N, Gong Y, Bi Y, Shi Y, Chen Z, Dai L, Wang J, Yang P.	Gut Microbes	10.1080/19490976.2021.1887722	2021
	Modulation of Saliva Microbiota through Prebiotic Intervention in HIV-Infected Individuals.	Jimenez-Hernandez N, Serrano-Villar S, Domingo A, Pons X, Artacho A, Estrada V, Moya A, Gosalbes MJ.	Nutrients	10.3390/nu11061346	2019
	Gut microbiota and COVID-19: A systematic review.	SeyedAlinaghi S, Afzalian A, Pashaei Z, Varshochi S, Karimi A, Mojdeganlou H, Mojdeganlou P, Razi A, Ghanadinezhad F, Shojaei A, Amiri A, Dashti M, Ghasemzadeh A, Dadras O, Mehraeen E, Afsahi AM.	Health Sci Rep	10.1002/hsr2.1080	2023
	Oral microbiome: possible harbinger for children's health.	Xiao J, Fiscella KA, Gill SR.	Int J Oral Sci	10.1038/s41368-020-0082-x	2020
	Sex-specific differences in the salivary microbiome of caries-active children.	Ortiz S, Herrman E, Lyashenko C, Purcell A, Raslan K, Khor B, Snow M, Forsyth A, Choi D, Maier T, Machida CA.	J Oral Microbiol	10.1080/20002297.2019.1653124	2019
Phylogeny	Oral microbiota in youth with perinatally acquired HIV infection.	Starr JR, Huang Y, Lee KH, Murphy CM, Moscicki AB, Shiboski CH, Ryder MI, Yao TJ, Faller LL, Van Dyke RB, Paster BJ, Pediatric HIV/AIDS Cohort Study.	Microbiome	10.1186/s40168-018-0484-6	2018
Metabolism	Evaluation of the gut microbiome in association with biological signatures of inflammation in murine polytrauma and shock.	Appiah SA, Foxx CL, Langgartner D, Palmer A, Zambrano CA, Braumuller S, Schaefer EJ, Wachter U, Elam BL, Radermacher P, Stamper CE, Heinze JD, Salazar SN, Luthens AK, Arnold AL, Reber SO, Huber-Lang M, Lowry CA, Halbgebauer R.	Sci Rep	10.1038/s41598-021-85897-w	2021
	Inter-personal diversity and temporal dynamics of dental, tongue, and salivary microbiota in the healthy oral cavity.	Hall MW, Singh N, Ng KF, Lam DK, Goldberg MB, Tenenbaum HC, Neufeld JD, G Beiko R, Senadheera DB.	NPJ Biofilms Microbiomes	10.1038/s41522-016-0011-0	2017
	Analysis of bacterial DNA in synovial tissue of Tunisian patients with reactive and undifferentiated arthritis by broad-range PCR, cloning and sequencing.	Siala M, Jaulhac B, Gdoura R, Sibilia J, Fourati H, Younes M, Baklouti S, Bargaoui N, Sellami S, Znazen A, Barthel C, Collin E, Hammami A, Sghir A.	Arthritis Res Ther	10.1186/ar2398	2008
	Utility of platforms Viteks MS and Microflex LT for the identification of complex clinical isolates that require molecular methods for their taxonomic classification.	Rocca MF, Barrios R, Zintgraff J, Martinez C, Irazu L, Vay C, Prieto M.	PLoS One	10.1371/journal.pone.0218077	2019
	Saliva microbiome, dietary, and genetic markers are associated with suicidal ideation in university students.	Ahrens AP, Sanchez-Padilla DE, Drew JC, Oli MW, Roesch LFW, Triplett EW.	Sci Rep	10.1038/s41598-022-18020-2	2022
Phylogeny	Host Genetic Control of the Oral Microbiome in Health and Disease.	Gomez A, Espinoza JL, Harkins DM, Leong P, Saffery R, Bockmann M, Torralba M, Kuelbs C, Kodukula R, Inman J, Hughes T, Craig JM, Highlander SK, Jones MB, Dupont CL, Nelson KE.	Cell Host Microbe	10.1016/j.chom.2017.08.013	2017
Phylogeny	Diversity within reference strains of Corynebacterium matruchotii includes Corynebacterium durum and a novel organism.	Barrett SL, Cookson BT, Carlson LC, Bernard KA, Coyle MB.	J Clin Microbiol	10.1128/jcm.39.3.943-948.2001	2001
Phylogeny	Caries-associated oral microbiome in head and neck cancer radiation patients: a longitudinal study.	Mougeot JC, Stevens CB, Almon KG, Paster BJ, Lalla RV, Brennan MT, Mougeot FB.	J Oral Microbiol	10.1080/20002297.2019.1586421	2019
	A spatial gradient of bacterial diversity in the human oral cavity shaped by salivary flow.	Proctor DM, Fukuyama JA, Loomer PM, Armitage GC, Lee SA, Davis NM, Ryder MI, Holmes SP, Relman DA.	Nat Commun	10.1038/s41467-018-02900-1	2018
	Panel 4: Recent advances in understanding the natural history of the otitis media microbiome and its response to environmental pressures.	Marsh RL, Aho C, Beissbarth J, Bialasiewicz S, Binks M, Cervin A, Kirkham LS, Lemon KP, Slack MPE, Smith-Vaughan HC.	Int J Pediatr Otorhinolaryngol	10.1016/j.ijporl.2019.109836	2020
	Composition and diversity of the subgingival microbiome and its relationship with age in postmenopausal women: an epidemiologic investigation.	LaMonte MJ, Genco RJ, Buck MJ, McSkimming DI, Li L, Hovey KM, Andrews CA, Zheng W, Sun Y, Millen AE, Tsompana M, Banack HR, Wactawski-Wende J.	BMC Oral Health	10.1186/s12903-019-0906-2	2019
	A prevalent and culturable microbiota links ecological balance to clinical stability of the human lung after transplantation.	Das S, Bernasconi E, Koutsokera A, Wurlod DA, Tripathi V, Bonilla-Rosso G, Aubert JD, Derkenne MF, Mercier L, Pattaroni C, Rapin A, von Garnier C, Marsland BJ, Engel P, Nicod LP.	Nat Commun	10.1038/s41467-021-22344-4	2021
Phylogeny	Inter-Individual Differences in the Oral Bacteriome Are Greater than Intra-Day Fluctuations in Individuals.	Sato Y, Yamagishi J, Yamashita R, Shinozaki N, Ye B, Yamada T, Yamamoto M, Nagasaki M, Tsuboi A.	PLoS One	10.1371/journal.pone.0131607	2015
Genetics	Role of Wax Ester Synthase/Acyl Coenzyme A:Diacylglycerol Acyltransferase in Oleaginous Streptomyces sp. Strain G25.	Rottig A, Strittmatter CS, Schauer J, Hiessl S, Poehlein A, Daniel R, Steinbuchel A.	Appl Environ Microbiol	10.1128/aem.01719-16	2016
Phylogeny	Evaluation of the RapID CB plus system for identification of coryneform bacteria and Listeria spp.	Funke G, Peters K, Aravena-Roman M.	J Clin Microbiol	10.1128/jcm.36.9.2439-2442.1998	1998
Phylogeny	Corynebacterium durum sp. nov., from human clinical specimens.	Riegel P, Heller R, Prevost G, Jehl F, Monteil H	Int J Syst Bacteriol	10.1099/00207713-47-4-1107	1997

References

#16295	Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 45333
#20215	Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 )
#20218	Verslyppe, B., De Smet, W., De Baets, B., De Vos, P., Dawyndt P.: StrainInfo introduces electronic passports for microorganisms.. Syst Appl Microbiol. 37: 42 - 50 2014 ( DOI 10.1016/j.syapm.2013.11.002 , PubMed 24321274 )
#23179	Philippe Riegel, Remy Heller, Gilles Prevost, Francois Jehl, Henri Monteil: Corynebacterium durum sp. nov., from Human Clinical Specimens. IJSEM 47: 1107 - 1111 1997 ( DOI 10.1099/00207713-47-4-1107 , PubMed 9336915 )
#34040	; Curators of the CIP;
#53611	Culture Collection University of Gothenburg (CCUG) ; Curators of the CCUG; CCUG 37331
#66792	Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) .
#67770	Japan Collection of Microorganism (JCM) ; Curators of the JCM;
#68371	Automatically annotated from API 50CH acid .
#68379	Automatically annotated from API Coryne .
#68382	Automatically annotated from API zym .
#69479	João F Matias Rodrigues, Janko Tackmann,Gregor Rot, Thomas SB Schmidt, Lukas Malfertheiner, Mihai Danaila,Marija Dmitrijeva, Daniela Gaio, Nicolas Näpflin and Christian von Mering. University of Zurich.: MicrobeAtlas 1.0 beta .
#118983	Collection of Institut Pasteur ; Curators of the CIP; CIP 105490
#124043	Isabel Schober, Julia Koblitz: Data extracted from sequence databases, automatically matched based on designation and taxonomy .
#125439	Philipp Münch, René Mreches, Martin Binder, Hüseyin Anil Gündüz, Xiao-Yin To, Alice McHardy: deepG: Deep Learning for Genome Sequence Data. R package version 0.3.1 .
#126262	A. Lissin, I. Schober, J. F. Witte, H. Lüken, A. Podstawka, J. Koblitz, B. Bunk, P. Dawyndt, P. Vandamme, P. de Vos, J. Overmann, L. C. Reimer: StrainInfo—the central database for linked microbial strain identifiers. ( DOI 10.1093/database/baaf059 )

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Corynebacterium durum (IFO 16161, LMG 19045, CIP 105490)

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