Corynebacterium flavescens (CCUG 28791, DSM 20296, ATCC 10340)

Name: Corynebacterium flavescens (CCUG 28791, DSM 20296, ATCC 10340)
Creator: BacDive
License: http://creativecommons.org/licenses/by/4.0/

BacDive ID 3085

Type strain

Strain Designation OJ8, OJ 8

Culture col. no. CCUG 28791 DSM 20296 ATCC 10340 NCDO 1320 NCIB 8707 20 more

NCBI tax ID(s) 28028

Special Collections DSMZ CCUG JCM KCTC CIP Wink compendium

History <- H.G. Schlegel <- K. Komagata <- ATCC <- R.N. Doetsch, OJ8 <- S. Orla-Jensen (Microbacterium flavum) K. Suzuki CNF 011 <-- AJ 1415 <-- ATCC 10340 <-- R. N. Doetsch OJ 8 <-- S. Orla-Jensen. CIP <- 1969, F. Gasser, Inst. Pasteur, Paris, France <- ATCC <- 1919, R.N. Doetsch: strain OJ 8 <- O. Jensen, Microbacterium flavum

Links

Corynebacterium flavescens OJ8 is a mesophilic prokaryote that was isolated from cheese.

mesophilic genome sequence 16S sequence

Name and taxonomic classification

SI-ID 13628

LMG 4046,ATCC 10340,CECT 536,DSM 20296,IAM 1642,IFO 14136,IMET 11080,JCM 1317,NCDO 1320,NCIB 8707,CCUG 28791,CCRC 12131,NCFB 1320,NCIMB 8707,VKM Ac-1956,CIP 69.5,KCTC 3414,AS 1.1885,NBRC 14136,NCCB 42012,LMD 42.12,BCRC 12131,IAM 12638,CGMCC 1.1885

@ref 20215

Last LPSN update 2026-02-09 11:18:25

Domain Bacteria

Phylum Actinomycetota

Class Actinomycetes

Order Mycobacteriales

Family Corynebacteriaceae

Genus Corynebacterium

Species Corynebacterium flavescens

Full scientific name Corynebacterium flavescens Barksdale et al. 1979 (Approved Lists 1980)

BacDive ID	Other strains from **Corynebacterium flavescens** (1)	Type strain
103170	C. flavescens STH00419(ZIMET), S298/F, HKI 0419

Morphology

Cell morphology

@ref	Confidence	Gram stain
125439	94.4
125438	94
125438	93.335	positive

Colony morphology

@ref	Colony color	Incubation period	Medium used
18637	Deep orange (2011)	10-14 days	ISP 2
18637	Signal yellow (1003)	10-14 days	ISP 3
18637	Ivory (1014)	10-14 days	ISP 4
18637	Signal yellow (1003)	10-14 days	ISP 5
18637	Colorless	10-14 days	ISP 6

Multicellular morphology

@ref	Forms multicellular complex	Medium name
18637		ISP 2
18637		ISP 3
18637		ISP 4
18637		ISP 5
18637		ISP 6

Multimedia

@ref:	8699
multimedia content:	DSM_20296.jpg
multimedia.multimedia content:	https://www.dsmz.de/microorganisms/photos/DSM_20296.jpg
caption:	Medium 693 37°C
intellectual property rights:	© Leibniz-Institut DSMZ
manual_annotation:	1

Culture and growth conditions

Culture medium

@ref	Name	Medium link	Composition
18637	ISP 2		Name: ISP 2 / Yeast Malt Agar (5265); 5265 Composition Malt extract 10.0 g/l Yeast extract 4.0 g/l Glucose 4.0 g/l Agar 15.0 g/l Preparation: Sterilisation: 20 minutes at 121°C pH before sterilisation: 7.0 Usage: Maintenance and Taxonomy Organisms: All Actinomycetes
18637	ISP 3		Name: ISP 3; 5315 Composition Dog oat flakes 20.0 g/l Trace element solution (5314) 2.5 ml/l Agar 18.0 g/l Preparation: Oat flakes are cooked for 20 minutes, trace element solution and agar are added (in the case of non rolled oat flakes the suspension has to bee filtrated). Sterilisation: 20 minutes at 121°C pH before sterilisation: 7.8 Usage: Maintenance and taxonomy (e.g. SEM As liquid medium for metabolite production) Organisms: All Actinomycetes Trace element solution 5314 Name: Trace element solution 5314; 5314 Composition CaCl2 x H2O 3.0 g/l Fe-III-citrate 1.0 g/l MnSO4 0.2 g/l ZnCl2 0.1 g/l CuSO4 x 5 H2O 0.025 g/l Sodium tetra borate 0.2 g/l CoCl2 x 6 H2O 0.004 g/l Sodium molybdate 0.01 g/l Preparation: Use double destillated water. Sterilisation: 20 minutes at 121°C pH before sterilisation: Usage: Trace element solution for different media Organisms:
18637	ISP 4		Name: ISP 4; DSM 547 Solution I: Difco soluble starch, 10.0 g. Make a paste of the starch with a small amount of cold distilled water and bring to a volume of 500 ml. Solution II: CaCO3 2.0 g K2HPO4 (anhydrous) 1.0 g MgSO4 x 7 H2O 1.0 g NaCl 1.0 g (NH4)2SO4 2.0 g Distilled water 500.0 ml Trace salt solution (see below) 1.0 ml The pH should be between 7.0 and 7.4. Do not adjust if it is within this range. Mix solutions I and II together. Add 20.0 g agar. Liquify agar by steaming at 100°C for 10 to 20 min. Trace element solution: FeSO4 x 7 H2O 0.1 g MnCl2 x 4 H2O 0.1 g ZnSO4 x 7 H2O 0.1 g Distilled water 100.0 ml
18637	ISP 5		Name: ISP 5 (5323) Composition L-Asparagine 1.0 g/l Glycerol 10.0 g/l K2HPO4 1.0 g/l Salt solution (see preparation) 1.0 ml/l Agar 20.0 g/l Preparation: Salt solution 1.0 g FeSO4 x 7 H2O 1.0 g MnCl2 x 4 H2O 1.0 g ZNSO4 x 7 H2O in 100 ml water Sterilisation: 20 minutes at 121°C pH before sterilisation: 7.2 Usage: Maintenance and taxonomy Organisms: All Actinomycetes
18637	ISP 6		Name: ISP 6 (5318) Composition Peptone 15.0 g/l Proteose peptose 5.0 g/l Ferric ammonium citrate 0.5 g/l Sodium glycerophosphate 1.0 g/l Sodium thiosulfate 0.08 g/l Yeast extract 1.0 g/l Agar 15.0 g/l Sterilisation: 20 minutes at 121°C pH before sterilisation: Usage: Production of melanoid pigments Organisms: All Actinomycetes
8699	TRYPTICASE SOY BROTH AGAR (DSMZ Medium 535)	Medium recipe at MediaDive	Name: TRYPTICASE SOY BROTH AGAR (DSMZ Medium 535) Composition: Trypticase soy broth 30.0 g/l Agar 15.0 g/l Distilled water
33457	MEDIUM 3 - Columbia agar		Columbia agar (39.000 g);distilled water (1000.000 ml)
119367	CIP Medium 3	Medium recipe at CIP

Culture temp

@ref	Growth	Type	Temperature (°C)	Range
8699	positive	growth	37	mesophilic
18637	positive	optimum	28	mesophilic
33457	positive	growth	30	mesophilic
67770	positive	growth	30	mesophilic

Physiology and metabolism

Oxygen tolerance

@ref	Oxygen tolerance	Confidence
125439	microaerophile	97.7

Halophily

@ref	Salt	Growth	Tested relation	Concentration
18637	NaCl	positive	maximum	7.5 %

Murein

@ref	Murein short key	Type
8699	A31	A1gamma m-Dpm-direct

Observation

67770

Observationquinones: MK-8(H₂), MK-9(H₂)

Metabolite utilization

@ref	Chebi-ID	Metabolite	Utilization activity	Kind of utilization tested
68371	27613 ChEBI	amygdalin	-	builds acid from	from API 50CH acid
68371	18305 ChEBI	arbutin	-	builds acid from	from API 50CH acid
68368	29016 ChEBI	arginine	-	hydrolysis	from API 20E
68371	17057 ChEBI	cellobiose	-	builds acid from	from API 50CH acid
68368	16947 ChEBI	citrate	-	assimilation	from API 20E
68371	17108 ChEBI	D-arabinose	-	builds acid from	from API 50CH acid
68371	18333 ChEBI	D-arabitol	-	builds acid from	from API 50CH acid
68371	15824 ChEBI	D-fructose	-	builds acid from	from API 50CH acid
68371	28847 ChEBI	D-fucose	-	builds acid from	from API 50CH acid
68371	12936 ChEBI	D-galactose	-	builds acid from	from API 50CH acid
68371	17634 ChEBI	D-glucose	-	builds acid from	from API 50CH acid
68371	62318 ChEBI	D-lyxose	-	builds acid from	from API 50CH acid
68371	16899 ChEBI	D-mannitol	-	builds acid from	from API 50CH acid
68371	16024 ChEBI	D-mannose	-	builds acid from	from API 50CH acid
68371	16988 ChEBI	D-ribose	-	builds acid from	from API 50CH acid
68371	17924 ChEBI	D-sorbitol	-	builds acid from	from API 50CH acid
68371	16443 ChEBI	D-tagatose	-	builds acid from	from API 50CH acid
68379	65327 ChEBI	D-xylose	-	fermentation	from API Coryne
68371	65327 ChEBI	D-xylose	-	builds acid from	from API 50CH acid
68371	17113 ChEBI	erythritol	-	builds acid from	from API 50CH acid
68379	4853 ChEBI	esculin	-	hydrolysis	from API Coryne
68371	4853 ChEBI	esculin	-	builds acid from	from API 50CH acid
68371	16813 ChEBI	galactitol	-	builds acid from	from API 50CH acid
68368	5291 ChEBI	gelatin	-	hydrolysis	from API 20E
68371	28066 ChEBI	gentiobiose	-	builds acid from	from API 50CH acid
68371	24265 ChEBI	gluconate	-	builds acid from	from API 50CH acid
68371	17754 ChEBI	glycerol	-	builds acid from	from API 50CH acid
68379	28087 ChEBI	glycogen	-	fermentation	from API Coryne
68371	28087 ChEBI	glycogen	-	builds acid from	from API 50CH acid
68371	15443 ChEBI	inulin	-	builds acid from	from API 50CH acid
68371	30849 ChEBI	L-arabinose	-	builds acid from	from API 50CH acid
68371	18403 ChEBI	L-arabitol	-	builds acid from	from API 50CH acid
68371	18287 ChEBI	L-fucose	-	builds acid from	from API 50CH acid
68371	62345 ChEBI	L-rhamnose	-	builds acid from	from API 50CH acid
68371	17266 ChEBI	L-sorbose	-	builds acid from	from API 50CH acid
68371	65328 ChEBI	L-xylose	-	builds acid from	from API 50CH acid
68379	17716 ChEBI	lactose	-	fermentation	from API Coryne
68371	17716 ChEBI	lactose	-	builds acid from	from API 50CH acid
68368	25094 ChEBI	lysine	-	degradation	from API 20E
68371	17306 ChEBI	maltose	-	builds acid from	from API 50CH acid
68371	6731 ChEBI	melezitose	-	builds acid from	from API 50CH acid
68371	28053 ChEBI	melibiose	-	builds acid from	from API 50CH acid
68371	320061 ChEBI	methyl alpha-D-glucopyranoside	-	builds acid from	from API 50CH acid
68371	43943 ChEBI	methyl alpha-D-mannoside	-	builds acid from	from API 50CH acid
68371	74863 ChEBI	methyl beta-D-xylopyranoside	-	builds acid from	from API 50CH acid
68371	17268 ChEBI	myo-inositol	-	builds acid from	from API 50CH acid
68371	59640 ChEBI	N-acetylglucosamine	-	builds acid from	from API 50CH acid
68379	17632 ChEBI	nitrate	-	reduction	from API Coryne
68368	18257 ChEBI	ornithine	-	degradation	from API 20E
68371		Potassium 2-ketogluconate	-	builds acid from	from API 50CH acid
68371		Potassium 5-ketogluconate	-	builds acid from	from API 50CH acid
68371	16634 ChEBI	raffinose	-	builds acid from	from API 50CH acid
68371	15963 ChEBI	ribitol	-	builds acid from	from API 50CH acid
68371	17814 ChEBI	salicin	-	builds acid from	from API 50CH acid
68371	28017 ChEBI	starch	-	builds acid from	from API 50CH acid
68379	17992 ChEBI	sucrose	+	fermentation	from API Coryne
68371	17992 ChEBI	sucrose	-	builds acid from	from API 50CH acid
68371	27082 ChEBI	trehalose	-	builds acid from	from API 50CH acid
68368	27897 ChEBI	tryptophan	-	energy source	from API 20E
68371	32528 ChEBI	turanose	-	builds acid from	from API 50CH acid
68368	16199 ChEBI	urea	-	hydrolysis	from API 20E
68371	17151 ChEBI	xylitol	-	builds acid from	from API 50CH acid

Metabolite production

@ref	Chebi-ID	Metabolite
68368	15688 ChEBI	acetoin	from API 20E
68368	16136 ChEBI	hydrogen sulfide	from API 20E
68368	35581 ChEBI	indole	from API 20E

Metabolite tests

@ref	Chebi-ID	Metabolite	Voges-proskauer-test	Indole test
68368	15688 ChEBI	acetoin	+		from API 20E
68368	35581 ChEBI	indole		-	from API 20E

Enzymes

@ref	Value	Activity	Ec
68382	acid phosphatase	+	3.1.3.2	from API zym
68382	alkaline phosphatase	+	3.1.3.1	from API zym
68382	alpha-chymotrypsin	-	3.4.21.1	from API zym
68382	alpha-fucosidase	-	3.2.1.51	from API zym
68382	alpha-galactosidase	-	3.2.1.22	from API zym
68382	alpha-glucosidase	-	3.2.1.20	from API zym
68379	alpha-glucosidase	-	3.2.1.20	from API Coryne
68382	alpha-mannosidase	-	3.2.1.24	from API zym
68368	arginine dihydrolase	-	3.5.3.6	from API 20E
68382	beta-galactosidase	-	3.2.1.23	from API zym
68368	beta-galactosidase	-	3.2.1.23	from API 20E
68382	beta-glucosidase	-	3.2.1.21	from API zym
68379	beta-glucosidase	-	3.2.1.21	from API Coryne
68382	beta-glucuronidase	-	3.2.1.31	from API zym
68379	catalase	+	1.11.1.6	from API Coryne
68382	cystine arylamidase	-	3.4.11.3	from API zym
68382	esterase (C 4)	+		from API zym
68382	esterase lipase (C 8)	+		from API zym
68368	gelatinase	-		from API 20E
68382	leucine arylamidase	+	3.4.11.1	from API zym
68382	lipase (C 14)	-		from API zym
68368	lysine decarboxylase	-	4.1.1.18	from API 20E
68382	N-acetyl-beta-glucosaminidase	-	3.2.1.52	from API zym
68379	N-acetyl-beta-glucosaminidase	-	3.2.1.52	from API Coryne
68382	naphthol-AS-BI-phosphohydrolase	+		from API zym
68368	ornithine decarboxylase	-	4.1.1.17	from API 20E
68379	pyrrolidonyl arylamidase	+	3.4.19.3	from API Coryne
68382	trypsin	-	3.4.21.4	from API zym
68368	tryptophan deaminase	-	4.1.99.1	from API 20E
68368	urease	-	3.5.1.5	from API 20E
68382	valine arylamidase	+		from API zym

Pathway annotation

Computationally determined by

@ref	pathway	enzyme coverage	annotated reactions
66794	palmitate biosynthesis	100	22 of 22
66794	glycolate and glyoxylate degradation	100	6 of 6
66794	ethanol fermentation	100	2 of 2
66794	cis-vaccenate biosynthesis	100	2 of 2
66794	acetate fermentation	100	4 of 4
66794	ppGpp biosynthesis	100	4 of 4
66794	methylglyoxal degradation	100	5 of 5
66794	propanol degradation	100	7 of 7
66794	acetoin degradation	100	3 of 3
66794	starch degradation	100	10 of 10
66794	vitamin K metabolism	100	5 of 5
66794	UDP-GlcNAc biosynthesis	100	3 of 3
66794	coenzyme A metabolism	100	4 of 4
66794	adipate degradation	100	2 of 2
66794	anapleurotic synthesis of oxalacetate	100	1 of 1
66794	suberin monomers biosynthesis	100	2 of 2
66794	CDP-diacylglycerol biosynthesis	100	2 of 2
66794	folate polyglutamylation	100	1 of 1
66794	threonine metabolism	90	9 of 10
66794	chorismate metabolism	88.89	8 of 9
66794	aspartate and asparagine metabolism	88.89	8 of 9
66794	serine metabolism	88.89	8 of 9
66794	valine metabolism	88.89	8 of 9
66794	CO2 fixation in Crenarchaeota	88.89	8 of 9
66794	alanine metabolism	86.21	25 of 29
66794	photosynthesis	85.71	12 of 14
66794	vitamin B1 metabolism	84.62	11 of 13
66794	phenylalanine metabolism	84.62	11 of 13
66794	glutamate and glutamine metabolism	82.14	23 of 28
66794	proline metabolism	81.82	9 of 11
66794	pentose phosphate pathway	81.82	9 of 11
66794	phenylacetate degradation (aerobic)	80	4 of 5
66794	lipoate biosynthesis	80	4 of 5
66794	glycogen metabolism	80	4 of 5
66794	flavin biosynthesis	80	12 of 15
66794	peptidoglycan biosynthesis	80	12 of 15
66794	biotin biosynthesis	75	3 of 4
66794	gluconeogenesis	75	6 of 8
66794	C4 and CAM-carbon fixation	75	6 of 8
66794	sulfopterin metabolism	75	3 of 4
66794	6-hydroxymethyl-dihydropterin diphosphate biosynthesis	75	6 of 8
66794	isoleucine metabolism	75	6 of 8
66794	lactate fermentation	75	3 of 4
66794	glycogen biosynthesis	75	3 of 4
66794	pyrimidine metabolism	73.33	33 of 45
66794	metabolism of disaccharids	72.73	8 of 11
66794	NAD metabolism	72.22	13 of 18
66794	cardiolipin biosynthesis	71.43	5 of 7
66794	glutathione metabolism	71.43	10 of 14
66794	citric acid cycle	71.43	10 of 14
66794	heme metabolism	71.43	10 of 14
66794	glycolysis	70.59	12 of 17
66794	propionate fermentation	70	7 of 10
66794	leucine metabolism	69.23	9 of 13
66794	tryptophan metabolism	68.42	26 of 38
66794	L-lactaldehyde degradation	66.67	2 of 3
66794	formaldehyde oxidation	66.67	2 of 3
66794	purine metabolism	64.89	61 of 94
66794	tetrahydrofolate metabolism	64.29	9 of 14
66794	methionine metabolism	61.54	16 of 26
66794	isoprenoid biosynthesis	61.54	16 of 26
66794	lipid metabolism	61.29	19 of 31
66794	non-pathway related	60.53	23 of 38
66794	oxidative phosphorylation	60.44	55 of 91
66794	gallate degradation	60	3 of 5
66794	4-hydroxyphenylacetate degradation	60	6 of 10
66794	ubiquinone biosynthesis	57.14	4 of 7
66794	d-mannose degradation	55.56	5 of 9
66794	cysteine metabolism	55.56	10 of 18
66794	phenol degradation	55	11 of 20
66794	arginine metabolism	54.17	13 of 24
66794	urea cycle	53.85	7 of 13
66794	lysine metabolism	52.38	22 of 42
66794	histidine metabolism	51.72	15 of 29
66794	dTDPLrhamnose biosynthesis	50	4 of 8
66794	sphingosine metabolism	50	3 of 6
66794	ketogluconate metabolism	50	4 of 8
66794	phenylmercury acetate degradation	50	1 of 2
66794	mannosylglycerate biosynthesis	50	1 of 2
66794	CMP-KDO biosynthesis	50	2 of 4
66794	butanoate fermentation	50	2 of 4
66794	cyclohexanol degradation	50	2 of 4
66794	sulfate reduction	46.15	6 of 13
66794	vitamin B6 metabolism	45.45	5 of 11
66794	molybdenum cofactor biosynthesis	44.44	4 of 9
66794	degradation of sugar alcohols	43.75	7 of 16
66794	androgen and estrogen metabolism	43.75	7 of 16
66794	reductive acetyl coenzyme A pathway	42.86	3 of 7
66794	tyrosine metabolism	42.86	6 of 14
66794	degradation of aromatic, nitrogen containing compounds	41.67	5 of 12
66794	glycine metabolism	40	4 of 10
66794	glycine betaine biosynthesis	40	2 of 5
66794	arachidonate biosynthesis	40	2 of 5
66794	degradation of pentoses	39.29	11 of 28
66794	enterobactin biosynthesis	33.33	1 of 3
66794	3-phenylpropionate degradation	33.33	5 of 15
66794	nitrate assimilation	33.33	3 of 9
66794	acetyl CoA biosynthesis	33.33	1 of 3
66794	IAA biosynthesis	33.33	1 of 3
66794	selenocysteine biosynthesis	33.33	2 of 6
66794	lipid A biosynthesis	33.33	3 of 9
66794	octane oxidation	33.33	1 of 3
66794	degradation of hexoses	33.33	6 of 18
66794	cyanate degradation	33.33	1 of 3
66794	(5R)-carbapenem carboxylate biosynthesis	33.33	1 of 3
66794	pantothenate biosynthesis	33.33	2 of 6
66794	4-hydroxymandelate degradation	33.33	3 of 9
66794	phenylpropanoid biosynthesis	30.77	4 of 13
66794	coenzyme M biosynthesis	30	3 of 10
66794	Entner Doudoroff pathway	30	3 of 10
66794	chlorophyll metabolism	27.78	5 of 18
66794	arachidonic acid metabolism	27.78	5 of 18
66794	ascorbate metabolism	27.27	6 of 22
66794	toluene degradation	25	1 of 4
66794	vitamin B12 metabolism	23.53	8 of 34
66794	allantoin degradation	22.22	2 of 9

Fatty acid profile

Metadata FA analysis

@ref

49381

Fatty acid	Percentage	ECL
C18:1 ω9c	47.9	17.769
C16:0	35.8	16
C14:0	6	14
C18:2 ω6,9c/C18:0 ANTE	6	17.724
C18:0	4.4	18

API 20E

@ref	ONPG	ADH (Arg)	LDC (Lys)	ODC	CIT	H2S productionH2S	URE	TDA (Trp)	IND	Acetoin production (Voges Proskauer test)VP	GEL	GLU	MAN	INO	Sor	RHA	SAC	MEL	AMY	ARA	OX	Nitrite productionNO2	Reduction to N2N2	MotilityMOB	Growth on MacConkey mediumMAC	OF-O	OF-F
18637	-	-	-	-	-	-	-	-	-	+	-	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.	not determinedn.d.

API coryne

@ref	Reduction of nitrateNIT	PYZ	PYRA	PAL	beta GUR	beta GAL	alpha GLU	beta NAG	ESC	URE	GEL	Control fermentationControl	GLU	RIB	XYL	MAN	MAL	LAC	SAC	GLYG	CAT
18637	-	+	+	-	+	+	-	-	-	+	+	not determinedn.d.	-	-	-	-	-	-	+	-	not determinedn.d.
49381	-	-	+	+	-	-	-	-	-	-	-	-	+	+	-	+	+	-	+	-	+

API zym

@ref	Control	Alkaline phosphatase	Esterase (C 4)	2-naphtyl caprylateEsterase Lipase (C 8)	Lipase (C 14)	L-leucyl-2-naphthylamideLeucine arylamidase	L-valyl-2-naphthylamideValine arylamidase	L-cystyl-2-naphthylamideCystine arylamidase	Trypsin	alpha- Chymotrypsin	Acid phosphatase	Naphthol-AS-BI-phosphateNaphthol-AS-BI-phosphohydrolase	alpha- Galactosidase	beta- Galactosidase	beta- Glucuronidase	alpha- Glucosidase	beta- Glucosidase	N-acetyl-beta- glucosaminidase	alpha- Mannosidase	alpha- Fucosidase
18637	not determinedn.d.	+	+	+	-	+	+	-	-	-	+	+	-	-	-	-	-	-	-	-

API 50CHac

@ref	ControlQ	GLY	ERY	DARA	LARA	RIB	DXYL	LXYL	ADO	MDX	GAL	GLU	FRU	MNE	SBE	RHA	DUL	INO	MAN	SOR	MDM	MDG	NAG	AMY	ARB	ESC	SAL	CEL	MAL	LAC	MEL	SAC	TRE	INU	MLZ	RAF	AMD	GLYG	XLT	GEN	TUR	LYX	TAG	DFUC	LFUC	DARL	LARL	GNT	2KG	5KG
119367	not determinedn.d.	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-

Isolation, sampling and environmental information

Isolation source categories

Cat1	Cat2	Cat3
#Engineered	#Food production	#Dairy product

Isolation

@ref	Sample type
8699	cheese
49381	Cheese
67770	Cheese
119367	Food, Cheese

Taxonmaps

69479

Global distribution of 16S sequence X84441 (>99% sequence identity) for Corynebacterium flavescens subclade from Microbeatlas

Aquatic Samples	161
Soil Samples	247
Animal Samples	1362
Plant Samples	29
Total Samples	1799

Interaction and safety

Risk assessment

@ref	Biosafety level	Biosafety level comment
18637	1	Risk group (German classification) According to TRBA 466
8699	1	Risk group (German classification) According to TRBA 466
119367	2	Risk group (French classification) According to TRBA 466

Sequence information

Genome sequences

@ref	Description	Assembly level	INSDC accession	BV-BRC accession	IMG accession	NCBI tax ID	Score
66792	ASM194146v1 assembly for Corynebacterium flavescens OJ8	complete	GCA_001941465	28028.4	2775507246	28028	96.94
67770	ASM869310v1 assembly for Corynebacterium flavescens CCUG 28791T	contig	GCA_008693105	28028.7	8111495375	28028	69.99
67770	ASM653946v1 assembly for Corynebacterium flavescens NBRC 14136	contig	GCA_006539465	28028.6		28028	60.62

16S sequences

@ref	Description	Accession	Length	Database	NCBI tax ID
20218	C.flavescens 16S ribosomal DNA	X82060	1409		28028
20218	Corynebacterium flavescens partial 16S rRNA gene, strain NCDO 1320	X84441	1489		28028

GC content

@ref	GC-content (mol%)	Method
8699	58.3
67770	58.3	thermal denaturation, midpoint method (Tm)
67770	59.9	genome sequence analysis
67770	56.8	thermal denaturation, midpoint method (Tm)
67770	58.6	thermal denaturation, midpoint method (Tm)

Genome-based predictions

Predictions

Predictions from Deep Learning for Genome Sequence Data. R package version 0.3.1 based on: Corynebacterium flavescens strain OJ8
PATRIC: 28028.4

@ref	Trait	Model	Prediction	Confidence in %	In training data
125439	spore_formation	BacteriaNetⓘ	no	88.60	no
125439	motility	BacteriaNetⓘ	no	94.40	no
125439	gram_stain	BacteriaNetⓘ	positive	87.60	no
125439	oxygen_tolerance	BacteriaNetⓘ	microaerophile	97.70	no

Predictions from bacterial phenotypic traits through improved machine learning using high-quality, curated datasets based on: Corynebacterium flavescens OJ8
NCBI: GCA_001941465.1

@ref	Trait	Model	Prediction	Confidence in %	In training data
125438	gram-positive	gram-positiveⓘ	yes	93.34	no
125438	anaerobic	anaerobicⓘ	no	93.43	no
125438	aerobic	aerobicⓘ	yes	58.27	no
125438	spore-forming	spore-formingⓘ	no	81.23	no
125438	thermophilic	thermophileⓘ	no	95.00	yes
125438	flagellated	motile2+ⓘ	no	94.00	no

Literature

Topic	Title	Authors	Journal	DOI	Year
	Genomic Sequence and Characteristics of EmiRose, a Bacteriophage Isolated on Corynebacterium flavescens.	Davis ER, Perry-Richardson B, Mohamed A, Ali I, Heller D, Sivanathan V.	Microbiol Resour Announc	10.1128/mra.00080-22	2022
Genetics	Tales of diversity: Genomic and morphological characteristics of forty-six Arthrobacter phages.	Klyczek KK, Bonilla JA, Jacobs-Sera D, Adair TL, Afram P, Allen KG, Archambault ML, Aziz RM, Bagnasco FG, Ball SL, Barrett NA, Benjamin RC, Blasi CJ, Borst K, Braun MA, Broomell H, Brown CB, Brynell ZS, Bue AB, Burke SO, Casazza W, Cautela JA, Chen K, Chimalakonda NS, Chudoff D, Connor JA, Cross TS, Curtis KN, Dahlke JA, Deaton BM, Degroote SJ, DeNigris DM, DeRuff KC, Dolan M, Dunbar D, Egan MS, Evans DR, Fahnestock AK, Farooq A, Finn G, Fratus CR, Gaffney BL, Garlena RA, Garrigan KE, Gibbon BC, Goedde MA, Guerrero Bustamante CA, Harrison M, Hartwell MC, Heckman EL, Huang J, Hughes LE, Hyduchak KM, Jacob AE, Kaku M, Karstens AW, Kenna MA, Khetarpal S, King RA, Kobokovich AL, Kolev H, Konde SA, Kriese E, Lamey ME, Lantz CN, Lapin JS, Lawson TO, Lee IY, Lee SM, Lee-Soety JY, Lehmann EM, London SC, Lopez AJ, Lynch KC, Mageeney CM, Martynyuk T, Mathew KJ, Mavrich TN, McDaniel CM, McDonald H, McManus CJ, Medrano JE, Mele FE, Menninger JE, Miller SN, Minick JE, Nabua CT, Napoli CK, Nkangabwa M, Oates EA, Ott CT, Pellerino SK, Pinamont WJ, Pirnie RT, Pizzorno MC, Plautz EJ, Pope WH, Pruett KM, Rickstrew G, Rimple PA, Rinehart CA, Robinson KM, Rose VA, Russell DA, Schick AM, Schlossman J, Schneider VM, Sells CA, Sieker JW, Silva MP, Silvi MM, Simon SE, Staples AK, Steed IL, Stowe EL, Stueven NA, Swartz PT, Sweet EA, Sweetman AT, Tender C, Terry K, Thomas C, Thomas DS, Thompson AR, Vanderveen L, Varma R, Vaught HL, Vo QD, Vonberg ZT, Ware VC, Warrad YM, Wathen KE, Weinstein JL, Wyper JF, Yankauskas JR, Zhang C, Hatfull GF.	PLoS One	10.1371/journal.pone.0180517	2017
Pathogenicity	New real-time PCR assay for rapid detection of methicillin-resistant Staphylococcus aureus directly from specimens containing a mixture of staphylococci.	Huletsky A, Giroux R, Rossbach V, Gagnon M, Vaillancourt M, Bernier M, Gagnon F, Truchon K, Bastien M, Picard FJ, van Belkum A, Ouellette M, Roy PH, Bergeron MG.	J Clin Microbiol	10.1128/jcm.42.5.1875-1884.2004	2004
Enzymology	Alkyl hydroperoxide reductases C and D are major antigens constitutively expressed by Mycobacterium avium subsp. paratuberculosis.	Olsen I, Reitan LJ, Holstad G, Wiker HG.	Infect Immun	10.1128/iai.68.2.801-808.2000	2000
Enzymology	Detection of Mycobacterium tuberculosis by PCR amplification with pan-Mycobacterium primers and hybridization to an M. tuberculosis-specific probe.	Tevere VJ, Hewitt PL, Dare A, Hocknell P, Keen A, Spadoro JP, Young KK.	J Clin Microbiol	10.1128/jcm.34.4.918-923.1996	1996
Biotechnology	Psychrotrophic Brocothrix thermosphacta bacteriophages isolated from beef.	Greer GG.	Appl Environ Microbiol	10.1128/aem.46.1.245-251.1983	1983
Phylogeny	Cellular fatty acid composition as an adjunct to the identification of asporogenous, aerobic gram-positive rods.	Bernard KA, Bellefeuille M, Ewan EP.	J Clin Microbiol	10.1128/jcm.29.1.83-89.1991	1991
Biotechnology	Tryptamine accumulates in cheese mainly via the decarboxylation of tryptophan by lactic acid bacteria.	Arranz D, Fernandez E, Szekeres B, Carvalho A, Rio BD, Redruello B, Alvarez MA.	Food Res Int	10.1016/j.foodres.2024.115380	2025
	Trichomycosis Axillaris: An Underdiagnosed Hair Shaft Condition.	Linan Barroso JM, Sanchez Rodriguez N.	Dermatol Pract Concept	10.5826/dpc.1402a134	2024
	Tryptamine accumulates in cheese mainly via the decarboxylation of tryptophan by lactic acid bacteria	Arranz D, Fernandez E, Szekeres B, Carvalho A, Del Rio B, Redruello B, Alvarez MA.	Food Research International.		2024
	Volatilome of brine-related microorganisms in a curd-based medium.	Innocente N, Renoldi N, Moret E, Maifreni M, Marino M.	J Dairy Sci	10.3168/jds.2022-23051	2023
	Ultraviolet-Induced Fluorescence Dermatoscopy of Trichobacteriosis Axillaris Reveals Peripilar Yellow-Green Luminescent Concretions.	Al-Nasiri M, Navarrete-Dechent C, Korecka K, Salwowska N, Goldust M, Pietkiewicz P.	Dermatol Pract Concept	10.5826/dpc.1302a169	2023
	Trichomycosis Axillaris: A Clinicoetiological Study.	Kalimuthu A, Thappa DM, Badhe B, Sistla S.	Indian Dermatol Online J	10.4103/idoj.idoj_756_24	2025
Enzymology	Enzyme mediated transformation of CO₂ into calcium carbonate using purified microbial carbonic anhydrase.	Sharma T, Sharma A, Xia CL, Lam SS, Khan AA, Tripathi S, Kumar R, Gupta VK, Nadda AK.	Environ Res	10.1016/j.envres.2022.113538	2022
	An Overview of Trichobacteriosis (Trichomycosis): An Underdiagnosed Disease.	Montes de Oca-Loyola ML, Lumban Ramirez P, Gomez-Daza F, Bonifaz A.	Cureus	10.7759/cureus.45964	2023
	[Trichomycosis (trichobacteriosis) capitis in an infant: Microbiological, dermoscopic and ultrastructural features].	Bonifaz A, Ramirez-Ricarte I, Rodriguez-Leviz A, Hernandez MA, Mena C, Valencia A.	Rev Chil Pediatr	10.1016/j.rchipe.2016.04.001	2017
Phylogeny	Diversity of microbiota found in coffee processing wastewater treatment plant.	Pires JF, Cardoso LS, Schwan RF, Silva CF.	World J Microbiol Biotechnol	10.1007/s11274-017-2372-9	2017
Genetics	Metagenomic and Culturomics Analysis of Microbial Communities within Surface Sediments and the Prevalence of Antibiotic Resistance Genes in a Pristine River: The Zaqu River in the Lancang River Source Region, China.	Yan Y, Xu J, Huang W, Fan Y, Li Z, Tian M, Ma J, Lu X, Liang J.	Microorganisms	10.3390/microorganisms12050911	2024
	Insights into Enzyme Reactions with Redox Cofactors in Biological Conversion of CO₂.	Kang DK, Kim SH, Sohn JH, Sung BH.	J Microbiol Biotechnol	10.4014/jmb.2306.06005	2023
	Dysbiosis of lower respiratory tract microbiome are associated with proinflammatory states in non-small cell lung cancer patients.	Li Y, Rao G, Zhu G, Cheng C, Yuan L, Li C, Gao J, Tang J, Wang Z, Li W.	Thorac Cancer	10.1111/1759-7714.15166	2024
	Chemical and microbiological characterization of two traditional Mongolian high-fat dairy products produced in Xilin Gol, China.	Guo L, Xu WL, Li CD, Guo YS, Ya M.	Food Sci Nutr	10.1002/fsn3.3283	2023
	Characterizing Peri-Implant and Sub-Gingival Microbiota through Culturomics. First Isolation of Some Species in the Oral Cavity. A Pilot Study.	Martellacci L, Quaranta G, Fancello G, D'Addona A, Sanguinetti M, Patini R, Masucci L.	Pathogens	10.3390/pathogens9050365	2020
	Pathogen Biocontrol Using Plant Growth-Promoting Bacteria (PGPR): Role of Bacterial Diversity.	Wang H, Liu R, You MP, Barbetti MJ, Chen Y.	Microorganisms	10.3390/microorganisms9091988	2021
	The chemical composition of essential oil and in vitro antibacterial activities of essential oil and methanol extract of Ziziphora persica Bunge.	Ozturk S, Ercisli S.	J Ethnopharmacol	10.1016/j.jep.2006.01.014	2006
	Application of Single Strand Conformation Polymorphism --PCR method for distinguishing cheese bacterial communities that inhibit Listeria monocytogenes.	Saubusse M, Millet L, Delbes C, Callon C, Montel MC.	Int J Food Microbiol	10.1016/j.ijfoodmicro.2006.12.024	2007
	Effect of Brazilian green propolis on microorganism contaminants of surface of Gorgonzola-type cheese.	Correa FT, de Souza AC, de Souza Junior EA, Isidoro SR, Piccoli RH, Dias DR, de Abreu LR.	J Food Sci Technol	10.1007/s13197-019-03664-2	2019
	Surface ripened cheeses: the effects of Debaryomyces hansenii, NaCl and pH on the intensity of pigmentation produced by Brevibacterium linens and Corynebacterium flavescens	Masoud W, Jakobsen M.	Int Dairy J	10.1016/s0958-6946(02)00147-4	2003
	Trichomycosis (trichobacteriosis): clinical and microbiological experience with 56 cases.	Bonifaz A, Vaquez-Gonzalez D, Fierro L, Araiza J, Ponce RM.	Int J Trichology	10.4103/0974-7753.114704	2013
	Distribution of Bacterial Endophytes in the Non-lesion Tissues of Potato and Their Response to Potato Common Scab.	Shi W, Su G, Li M, Wang B, Lin R, Yang Y, Wei T, Zhou B, Gao Z.	Front Microbiol	10.3389/fmicb.2021.616013	2021
	Gut diversity and the resistome as biomarkers of febrile neutropenia outcome in paediatric oncology patients undergoing hematopoietic stem cell transplantation.	Sardzikova S, Andrijkova K, Svec P, Beke G, Klucar L, Minarik G, Bielik V, Kolenova A, Soltys K.	Sci Rep	10.1038/s41598-024-56242-8	2024
	Clinical and epidemiological features of coryneform skin infections at a tertiary hospital.	Pinto M, Hundi GK, Bhat RM, Bala NK, Dandekeri S, Martis J, Kambil SM.	Indian Dermatol Online J	10.4103/2229-5178.182351	2016
	Multidirectional Characterization of Phytochemical Profile and Health-Promoting Effects of Ziziphora bungeana Juz. Extracts.	Zhaparkulova K, Karaubayeva A, Sakipova Z, Biernasiuk A, Gawel-Beben K, Laskowski T, Kusniyeva A, Omargali A, Bekezhanova T, Ibragimova L, Ibadullayeva G, Jakiyanov A, Czech K, Tastambek K, Glowniak K, Malm A, Kukula-Koch W.	Molecules	10.3390/molecules27248994	2022
	Composition, Succession, and Source Tracking of Microbial Communities throughout the Traditional Production of a Farmstead Cheese.	Sun L, D'Amico DJ.	mSystems	10.1128/msystems.00830-21	2021
	Endophytic bacteria in rice seeds inhibit early colonization of roots by Azospirillum brasilense	Bacilio-Jimenez M, Aguilar-Flores S, Valle MVd, Perez A, Zepeda A, Zenteno E.	Soil Biol Biochem	10.1016/s0038-0717(00)00126-7	2001
	Identification of a New Antibacterial Sulfur Compound from Raphanus sativus Seeds.	Jadoun J, Yazbak A, Rushrush S, Rudy A, Azaizeh H.	Evid Based Complement Alternat Med	10.1155/2016/9271285	2016
	The Influence of pH, NaCl, and the Deacidifying Yeasts Debaryomyces hansenii and Kluyveromyces marxianus on the Production of Pigments by the Cheese-Ripening Bacteria Arthrobacter arilaitensis.	Sutthiwong N, Fouillaud M, Dufosse L.	Foods	10.3390/foods7110190	2018
	An Update on Novel Taxa and Revised Taxonomic Status of Bacteria Isolated from Domestic Animals Described in 2018 to 2021.	Munson E, Lawhon SD, Burbick CR, Zapp A, Villaflor M, Thelen E.	J Clin Microbiol	10.1128/jcm.00281-22	2023
Phylogeny	Monitoring bacterial communities in raw milk and cheese by culture-dependent and -independent 16S rRNA gene-based analyses.	Delbes C, Ali-Mandjee L, Montel MC.	Appl Environ Microbiol	10.1128/aem.01716-06	2007
Phylogeny	Bacterial community dynamics during production of registered designation of origin Salers cheese as evaluated by 16S rRNA gene single-strand conformation polymorphism analysis.	Duthoit F, Godon JJ, Montel MC.	Appl Environ Microbiol	10.1128/aem.69.7.3840-3848.2003	2003
	Widespread abundance of functional bacterial amyloid in mycolata and other gram-positive bacteria.	Jordal PB, Dueholm MS, Larsen P, Petersen SV, Enghild JJ, Christiansen G, Hojrup P, Nielsen PH, Otzen DE.	Appl Environ Microbiol	10.1128/aem.02107-08	2009
	Growth characteristics of Brevibacterium, Corynebacterium, Microbacterium, and Staphylococcus spp. isolated from surface-ripened cheese.	Mounier J, Rea MC, O'Connor PM, Fitzgerald GF, Cogan TM.	Appl Environ Microbiol	10.1128/aem.01260-07	2007
Phylogeny	Biodiversity of the bacterial flora on the surface of a smear cheese.	Brennan NM, Ward AC, Beresford TP, Fox PF, Goodfellow M, Cogan TM.	Appl Environ Microbiol	10.1128/aem.68.2.820-830.2002	2002
	Nucleic acid-based approaches to investigate microbial-related cheese quality defects.	O'Sullivan DJ, Giblin L, McSweeney PL, Sheehan JJ, Cotter PD.	Front Microbiol	10.3389/fmicb.2013.00001	2013
Genetics	Genome-Based Taxonomic Classification of the Phylum Actinobacteria.	Nouioui I, Carro L, Garcia-Lopez M, Meier-Kolthoff JP, Woyke T, Kyrpides NC, Pukall R, Klenk HP, Goodfellow M, Goker M.	Front Microbiol	10.3389/fmicb.2018.02007	2018
Pathogenicity	Peptide nucleic acid-mediated competitive PCR clamping for detection of rifampin-resistant Mycobacterium tuberculosis.	Iwamoto T, Sonobe T.	Antimicrob Agents Chemother	10.1128/aac.48.10.4023-4026.2004	2004
Pathogenicity	Rescuing activity of galactoglycerolipids from cellular lesions induced by 5-aminolevulinic acid.	Nakata K	J Biochem	10.1093/oxfordjournals.jbchem.a022674	2000
Phylogeny	Corynebacterium endometrii sp. nov., isolated from the uterus of a cow with endometritis.	Ballas P, Ruckert C, Wagener K, Drillich M, Kampfer P, Busse HJ, Ehling-Schulz M.	Int J Syst Evol Microbiol	10.1099/ijsem.0.003728	2020
Phylogeny	Corynebacterium lizhenjunii sp. nov., isolated from the respiratory tract of Marmota himalayana, and Corynebacterium qintianiae sp. nov., isolated from the lung tissue of Pseudois nayaur.	Zhou J, Xu M, Guo W, Yang J, Pu J, Lai XH, Jin D, Lu S, Zhang S, Huang Y, Zhu W, Huang Y, Zheng H, Xu J.	Int J Syst Evol Microbiol	10.1099/ijsem.0.004803	2021

References

#8699	Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 20296
#18637	Wink, J.: Compendium of Actinobacteria. HZI-Helmholtz-Centre for Infection Research, Braunschweig .
#20215	Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 )
#20218	Verslyppe, B., De Smet, W., De Baets, B., De Vos, P., Dawyndt P.: StrainInfo introduces electronic passports for microorganisms.. Syst Appl Microbiol. 37: 42 - 50 2014 ( DOI 10.1016/j.syapm.2013.11.002 , PubMed 24321274 )
#33457	; Curators of the CIP;
#49381	Culture Collection University of Gothenburg (CCUG) ; Curators of the CCUG; CCUG 28791
#66792	Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) .
#66794	Antje Chang, Lisa Jeske, Sandra Ulbrich, Julia Hofmann, Julia Koblitz, Ida Schomburg, Meina Neumann-Schaal, Dieter Jahn, Dietmar Schomburg: BRENDA, the ELIXIR core data resource in 2021: new developments and updates. Nucleic Acids Res. 49: D498 - D508 2020 ( DOI 10.1093/nar/gkaa1025 , PubMed 33211880 )
#67770	Japan Collection of Microorganism (JCM) ; Curators of the JCM;
#68368	Automatically annotated from API 20E .
#68371	Automatically annotated from API 50CH acid .
#68379	Automatically annotated from API Coryne .
#68382	Automatically annotated from API zym .
#69479	João F Matias Rodrigues, Janko Tackmann,Gregor Rot, Thomas SB Schmidt, Lukas Malfertheiner, Mihai Danaila,Marija Dmitrijeva, Daniela Gaio, Nicolas Näpflin and Christian von Mering. University of Zurich.: MicrobeAtlas 1.0 beta .
#119367	Collection of Institut Pasteur ; Curators of the CIP; CIP 69.5
#125438	Julia Koblitz, Lorenz Christian Reimer, Rüdiger Pukall, Jörg Overmann: Predicting bacterial phenotypic traits through improved machine learning using high-quality, curated datasets. 2024 ( DOI 10.1101/2024.08.12.607695 )
#125439	Philipp Münch, René Mreches, Martin Binder, Hüseyin Anil Gündüz, Xiao-Yin To, Alice McHardy: deepG: Deep Learning for Genome Sequence Data. R package version 0.3.1 .
#126262	A. Lissin, I. Schober, J. F. Witte, H. Lüken, A. Podstawka, J. Koblitz, B. Bunk, P. Dawyndt, P. Vandamme, P. de Vos, J. Overmann, L. C. Reimer: StrainInfo—the central database for linked microbial strain identifiers. ( DOI 10.1093/database/baaf059 )

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Corynebacterium flavescens (CCUG 28791, DSM 20296, ATCC 10340)

Name and taxonomic classification

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