Cryptobacterium curtum 12-3 is an anaerobe, mesophilic, Gram-positive prokaryote that forms circular colonies and was isolated from peridontal pocket of an adult with peridontal disease.
Gram-positive rod-shaped colony-forming anaerobe mesophilic genome sequence 16S sequence| @ref 20215 |
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Last LPSN update
2025-12-16 09:47:27 |
| Domain Bacillati |
| Phylum Actinomycetota |
| Class Coriobacteriia |
| Order Eggerthellales |
| Family Eggerthellaceae |
| Genus Cryptobacterium |
| Species Cryptobacterium curtum |
| Full scientific name Cryptobacterium curtum Nakazawa et al. 1999 |
| BacDive ID | Other strains from Cryptobacterium curtum (2) | Type strain |
|---|---|---|
| 151033 | C. curtum CCUG 43106 | |
| 151901 | C. curtum CCUG 45151 B |
| @ref | Name | Growth | Medium link | Composition | |
|---|---|---|---|---|---|
| 6011 | CHOPPED MEAT MEDIUM (DSMZ Medium 78) | Medium recipe at MediaDive  | Name: CHOPPED MEAT MEDIUM (DSMZ Medium 78) Composition: Ground beef 500.0 g/l Casitone 30.0 g/l Agar 15.0 g/l Ethanol 9.5 g/l (optional) K2HPO4 5.0 g/l Yeast extract 5.0 g/l L-Cysteine HCl 0.5 g/l Haemin 0.005 g/l (optional) Resazurin 0.001 g/l Vitamin K3 0.0005 g/l (optional) Vitamin K1 (optional) NaOH (optional) Distilled water | ||
| 23098 | Brain Heart Infusion-blood agar plates |
| @ref | Chebi-ID | Metabolite | Utilization activity | Kind of utilization tested | |
|---|---|---|---|---|---|
| 23098 | 27613 ChEBI | amygdalin | - | assimilation | |
| 23098 | 22599 ChEBI | arabinose | - | assimilation | |
| 23098 | 17057 ChEBI | cellobiose | - | assimilation | |
| 23098 | 17113 ChEBI | erythritol | - | assimilation | |
| 23098 | 4853 ChEBI | esculin | - | assimilation | |
| 23098 | 4853 ChEBI | esculin | - | hydrolysis | |
| 23098 | 28757 ChEBI | fructose | - | assimilation | |
| 23098 | 28260 ChEBI | galactose | - | assimilation | |
| 23098 | 17234 ChEBI | glucose | - | assimilation | |
| 23098 | 28087 ChEBI | glycogen | - | assimilation | |
| 23098 | 17716 ChEBI | lactose | - | assimilation | |
| 23098 | 17306 ChEBI | maltose | - | assimilation | |
| 23098 | 29864 ChEBI | mannitol | - | assimilation | |
| 23098 | 37684 ChEBI | mannose | - | assimilation | |
| 23098 | 6731 ChEBI | melezitose | - | assimilation | |
| 23098 | 28053 ChEBI | melibiose | - | assimilation | |
| 23098 | 17268 ChEBI | myo-inositol | - | assimilation | |
| 23098 | 17632 ChEBI | nitrate | - | reduction | |
| 23098 | 26546 ChEBI | rhamnose | - | assimilation | |
| 23098 | 15963 ChEBI | ribitol | - | assimilation | |
| 23098 | 33942 ChEBI | ribose | - | assimilation | |
| 23098 | 17814 ChEBI | salicin | - | assimilation | |
| 23098 | 30911 ChEBI | sorbitol | - | assimilation | |
| 23098 | 28017 ChEBI | starch | - | assimilation | |
| 23098 | 28017 ChEBI | starch | - | hydrolysis | |
| 23098 | 17992 ChEBI | sucrose | - | assimilation | |
| 23098 | 27082 ChEBI | trehalose | - | assimilation | |
| 23098 | 18222 ChEBI | xylose | - | assimilation |
| @ref | Description | Assembly level | INSDC accession | BV-BRC accession | IMG accession | NCBI tax ID | Score | |
|---|---|---|---|---|---|---|---|---|
| 66792 | ASM2384v1 assembly for Cryptobacterium curtum DSM 15641 | complete | GCA_000023845   | 469378.5  | 644736346  | 469378 | 99.14 |  |
| @ref | Description | Accession | Length | Database | NCBI tax ID | |
|---|---|---|---|---|---|---|
| 6011 | Cryptobacterium curtum gene for 16S rRNA, partial sequence | AB019260 | 1429 |  | 469378 |
| Topic | Title | Authors | Journal | DOI | Year | |
|---|---|---|---|---|---|---|
| Identification of an anti-CRISPR protein that inhibits the CRISPR-Cas type I-B system in Clostridioides difficile. | Muzyukina P, Shkaruta A, Guzman NM, Andreani J, Borges AL, Bondy-Denomy J, Maikova A, Semenova E, Severinov K, Soutourina O. | mSphere | 10.1128/msphere.00401-23 | 2023 | | |
| Periodontal Pathogens Correlate with Rheumatoid Arthritis Disease Parameters: A Systematic Review Based on Clinical Studies. | Astuti L, Masulili SLC, Gunardi I, Sulijaya B, Soeroso Y. | Dent J (Basel) | 10.3390/dj13050214 | 2025 | | |
| Assessment of Prognostic Factors, Clinical Features Including the Microbiome, and Treatment Outcomes in Patients with Cancer of Unknown Primary Site. | Dorobisz K, Dorobisz T, Pazdro-Zastawny K. | Cancers (Basel) | 10.3390/cancers16193416 | 2024 | | |
| Subgingival Microbiome in Pregnancy and a Potential Relationship to Early Term Birth. | Yang I, Claussen H, Arthur RA, Hertzberg VS, Geurs N, Corwin EJ, Dunlop AL. | Front Cell Infect Microbiol | 10.3389/fcimb.2022.873683 | 2022 | | |
| Harnessing the Microbiome: A Comprehensive Review on Advancing Therapeutic Strategies for Rheumatic Diseases. | Bhattacharjee P, Karim KA, Khan Z. | Cureus | 10.7759/cureus.50964 | 2023 | | |
| Clinical and microbiological assessment in a subpopulation of young Argentine patients with severe periodontitis. | Pontarolo C, Bozza FL, Galli FG, Bonta H, Molgatini SL, Caride F, Gliosca LA. | Acta Odontol Latinoam | 10.54589/aol.36/1/24 | 2023 | | |
| Metabolism | Oral microbiome correlates with selected clinical biomarkers in individuals with no significant systemic disease. | Lim MY, Kim JH, Nam YD. | Front Cell Infect Microbiol | 10.3389/fcimb.2023.1114014 | 2023 | |
| Genetics | Oral Microbiome in Nonsmoker Patients with Oral Cavity Squamous Cell Carcinoma, Defined by Metagenomic Shotgun Sequencing. | Ganly I, Hao Y, Rosenthal M, Wang H, Migliacci J, Huang B, Katabi N, Brown S, Tang YW, Pei Z, Yang L. | Cancers (Basel) | 10.3390/cancers14246096 | 2022 | |
| Genetics | Comprehensive human respiratory genome catalogue underlies the high resolution and precision of the respiratory microbiome. | Li Y, Pan G, Wang S, Li Z, Yang R, Jiang Y, Chen Y, Li SC, Shen B. | Brief Bioinform | 10.1093/bib/bbae620 | 2024 | |
| Pathogenicity | Long-Term Analysis of Resilience of the Oral Microbiome in Allogeneic Stem Cell Transplant Recipients. | Laheij AMGA, Rozema FR, Brennan MT, von Bultzingslowen I, van Leeuwen SJM, Potting C, Huysmans MDNJM, Hazenberg MD, Brandt BW, Zaura E, Buijs MJ, de Soet JJ, Blijlevens NNM, Raber-Durlacher JE. | Microorganisms | 10.3390/microorganisms10040734 | 2022 | |
| Heterogeneous lineage-specific arginine deiminase expression within dental microbiome species. | Mann AE, Chakraborty B, O'Connell LM, Nascimento MM, Burne RA, Richards VP. | Microbiol Spectr | 10.1128/spectrum.01445-23 | 2024 | | |
| Dysbiotic Subgingival Microbial Communities in Periodontally Healthy Patients With Rheumatoid Arthritis. | Lopez-Oliva I, Paropkari AD, Saraswat S, Serban S, Yonel Z, Sharma P, de Pablo P, Raza K, Filer A, Chapple I, Dietrich T, Grant MM, Kumar PS. | Arthritis Rheumatol | 10.1002/art.40485 | 2018 | | |
| Microbiome in Rheumatoid Arthritis and Celiac Disease: A Friend or Foe. | Elsouri K, Arboleda V, Heiser S, Kesselman MM, Demory Beckler M. | Cureus | 10.7759/cureus.15543 | 2021 | | |
| Multi-omics analysis reveals the key factors involved in the severity of the Alzheimer's disease. | Meng L, Jin H, Yulug B, Altay O, Li X, Hanoglu L, Cankaya S, Coskun E, Idil E, Nogaylar R, Ozsimsek A, Shoaie S, Turkez H, Nielsen J, Zhang C, Boren J, Uhlen M, Mardinoglu A. | Alzheimers Res Ther | 10.1186/s13195-024-01578-6 | 2024 | | |
| Metabolism | Metabolism of Daidzein and Genistein by Gut Bacteria of the Class Coriobacteriia. | Soukup ST, Stoll DA, Danylec N, Schoepf A, Kulling SE, Huch M. | Foods | 10.3390/foods10112741 | 2021 | |
| Novel Pathogens in Periodontal Microbiology. | Hiranmayi KV, Sirisha K, Ramoji Rao MV, Sudhakar P. | J Pharm Bioallied Sci | 10.4103/jpbs.jpbs_288_16 | 2017 | | |
| Subgingival Microbiome in Rheumatoid Arthritis Patients with Periodontitis. | Chen YJ, Hung WC, Chou YH, Lai CH, Peng P, Jhou PS, Tsai MR, Sheu JJ, Yen JH. | Int J Mol Sci | 10.3390/ijms23179883 | 2022 | | |
| Pathogenicity | Influence of Oral Microbiota on the Presence of IgA Anti-Citrullinated Protein Antibodies in Gingival Crevicular Fluid. | de Smit MJ, Rahajoe PS, Raveling-Eelsing E, Lisotto P, Harmsen HJM, Kertia N, Vissink A, Westra J. | Front Oral Health | 10.3389/froh.2022.904711 | 2022 | |
| Pathogenicity | Salivary Microbiota and Host-Inflammatory Responses in Periodontitis Affected Individuals With and Without Rheumatoid Arthritis. | Eriksson K, Lundmark A, Delgado LF, Hu YOO, Fei G, Lee L, Fei C, Catrina AI, Jansson L, Andersson AF, Yucel-Lindberg T. | Front Cell Infect Microbiol | 10.3389/fcimb.2022.841139 | 2022 | |
| Genetics | Genomic Landscape Highlights Molecular Mechanisms Involved in Silicate Solubilization, Stress Tolerance, and Potential Growth-Promoting Activity of Bacterium Enterobacter sp. LR6. | Raturi G, Sharma Y, Mandlik R, Kumawat S, Rana N, Dhar H, Tripathi DK, Sonah H, Sharma TR, Deshmukh R. | Cells | 10.3390/cells11223622 | 2022 | |
| The microbiology of the acute dental abscess. | Robertson D, Smith AJ. | J Med Microbiol | 10.1099/jmm.0.003517-0 | 2009 | | |
| Pathogenicity | Silver nanoparticles produced from Cedecea sp. exhibit antibiofilm activity and remarkable stability. | Singh P, Pandit S, Jers C, Joshi AS, Garnaes J, Mijakovic I. | Sci Rep | 10.1038/s41598-021-92006-4 | 2021 | |
| Improving the microbial sampling and analysis of secondary infected root canals by passive ultrasonic irrigation. | Kluge M, Truschler J, Elamin F, Anderson A, Hellwig E, Altenburger M, Vach K, Wittmer A, Al-Ahmad A. | Clin Oral Investig | 10.1007/s00784-022-04424-x | 2022 | | |
| Microbial role in periodontitis: Have we reached the top? Some unsung bacteria other than red complex. | Arora N, Mishra A, Chugh S. | J Indian Soc Periodontol | 10.4103/0972-124x.128192 | 2014 | | |
| Metabolism | Elucidating regulatory processes of intense physical activity by multi-omics analysis. | Nakayasu ES, Gritsenko MA, Kim YM, Kyle JE, Stratton KG, Nicora CD, Munoz N, Navarro KM, Claborne D, Gao Y, Weitz KK, Paurus VL, Bloodsworth KJ, Allen KA, Bramer LM, Montes F, Clark KA, Tietje G, Teeguarden J, Burnum-Johnson KE. | Mil Med Res | 10.1186/s40779-023-00477-5 | 2023 | |
| Genetics | Evolution of transcriptional regulation of histidine metabolism in Gram-positive bacteria. | Ashniev GA, Sernova NV, Shevkoplias AE, Rodionov ID, Rodionova IA, Vitreschak AG, Gelfand MS, Rodionov DA. | BMC Genomics | 10.1186/s12864-022-08796-y | 2022 | |
| New bacterial species associated with chronic periodontitis. | Kumar PS, Griffen AL, Barton JA, Paster BJ, Moeschberger ML, Leys EJ. | J Dent Res | 10.1177/154405910308200503 | 2003 | | |
| Ortholog-Finder: A Tool for Constructing an Ortholog Data Set. | Horiike T, Minai R, Miyata D, Nakamura Y, Tateno Y. | Genome Biol Evol | 10.1093/gbe/evw005 | 2016 | | |
| Ray: simultaneous assembly of reads from a mix of high-throughput sequencing technologies. | Boisvert S, Laviolette F, Corbeil J. | J Comput Biol | 10.1089/cmb.2009.0238 | 2010 | | |
| Phylogeny | Characterisation of Eubacterium-like strains isolated from oral infections. | Downes J, Munson MA, Spratt DA, Kononen E, Tarkka E, Jousimies-Somer H, Wade WG. | J Med Microbiol | 10.1099/0022-1317-50-11-947 | 2001 | |
| Mobile element warfare via CRISPR and anti-CRISPR in Pseudomonas aeruginosa. | Leon LM, Park AE, Borges AL, Zhang JY, Bondy-Denomy J. | Nucleic Acids Res | 10.1093/nar/gkab006 | 2021 | | |
| Dissemination of 6S RNA among bacteria. | Wehner S, Damm K, Hartmann RK, Marz M. | RNA Biol | 10.4161/rna.29894 | 2014 | | |
| Enzymology | Increased citrullination and expression of peptidylarginine deiminases independently of P. gingivalis and A. actinomycetemcomitans in gingival tissue of patients with periodontitis. | Engstrom M, Eriksson K, Lee L, Hermansson M, Johansson A, Nicholas AP, Gerasimcik N, Lundberg K, Klareskog L, Catrina AI, Yucel-Lindberg T. | J Transl Med | 10.1186/s12967-018-1588-2 | 2018 | |
| Proteome | The human postsynaptic density shares conserved elements with proteomes of unicellular eukaryotes and prokaryotes. | Emes RD, Grant SG. | Front Neurosci | 10.3389/fnins.2011.00044 | 2011 | |
| Genetics | IMG: the Integrated Microbial Genomes database and comparative analysis system. | Markowitz VM, Chen IM, Palaniappan K, Chu K, Szeto E, Grechkin Y, Ratner A, Jacob B, Huang J, Williams P, Huntemann M, Anderson I, Mavromatis K, Ivanova NN, Kyrpides NC. | Nucleic Acids Res | 10.1093/nar/gkr1044 | 2012 | |
| Comparative Metatranscriptomics of Periodontitis Supports a Common Polymicrobial Shift in Metabolic Function and Identifies Novel Putative Disease-Associated ncRNAs. | Ram-Mohan N, Meyer MM. | Front Microbiol | 10.3389/fmicb.2020.00482 | 2020 | | |
| Extensive description and comparison of human supra-gingival microbiome in root caries and health. | Chen L, Qin B, Du M, Zhong H, Xu Q, Li Y, Zhang P, Fan M. | PLoS One | 10.1371/journal.pone.0117064 | 2015 | | |
| Red fluorescent biofilm: the thick, the old, and the cariogenic. | Volgenant CM, Hoogenkamp MA, Buijs MJ, Zaura E, Ten Cate JM, van der Veen MH. | J Oral Microbiol | 10.3402/jom.v8.30346 | 2016 | | |
| Phylogeny | Diversity of bacterial populations on the tongue dorsa of patients with halitosis and healthy patients. | Kazor CE, Mitchell PM, Lee AM, Stokes LN, Loesche WJ, Dewhirst FE, Paster BJ. | J Clin Microbiol | 10.1128/jcm.41.2.558-563.2003 | 2003 | |
| Genetics | A Genomic Toolkit for the Mechanistic Dissection of Intractable Human Gut Bacteria. | Bisanz JE, Soto-Perez P, Noecker C, Aksenov AA, Lam KN, Kenney GE, Bess EN, Haiser HJ, Kyaw TS, Yu FB, Rekdal VM, Ha CWY, Devkota S, Balskus EP, Dorrestein PC, Allen-Vercoe E, Turnbaugh PJ. | Cell Host Microbe | 10.1016/j.chom.2020.04.006 | 2020 | |
| Temporal Shifts in Microbial Communities in Nonpregnant African-American Women with and without Bacterial Vaginosis. | Wertz J, Isaacs-Cosgrove N, Holzman C, Marsh TL. | Interdiscip Perspect Infect Dis | 10.1155/2008/181253 | 2008 | | |
| Phylogeny | Across bacterial phyla, distantly-related genomes with similar genomic GC content have similar patterns of amino acid usage. | Lightfield J, Fram NR, Ely B. | PLoS One | 10.1371/journal.pone.0017677 | 2011 | |
| Beyond microbial community composition: functional activities of the oral microbiome in health and disease. | Duran-Pinedo AE, Frias-Lopez J. | Microbes Infect | 10.1016/j.micinf.2015.03.014 | 2015 | | |
| Metabolism | The variable subdomain of Escherichia coli SecA functions to regulate SecA ATPase activity and ADP release. | Das S, Grady LM, Michtavy J, Zhou Y, Cohan FM, Hingorani MM, Oliver DB. | J Bacteriol | 10.1128/jb.00039-12 | 2012 | |
| Annotation of Protein Domains Reveals Remarkable Conservation in the Functional Make up of Proteomes Across Superkingdoms. | Nasir A, Naeem A, Khan MJ, Nicora HD, Caetano-Anolles G. | Genes (Basel) | 10.3390/genes2040869 | 2011 | | |
| Genetics | Developmental biology of Streptomyces from the perspective of 100 actinobacterial genome sequences. | Chandra G, Chater KF. | FEMS Microbiol Rev | 10.1111/1574-6976.12047 | 2014 | |
| Phylogeny | Phylogenetic framework and molecular signatures for the main clades of the phylum Actinobacteria. | Gao B, Gupta RS. | Microbiol Mol Biol Rev | 10.1128/mmbr.05011-11 | 2012 | |
| Genetics | Complete genome sequence of Cryptobacterium curtum type strain (12-3). | Mavrommatis K, Pukall R, Rohde C, Chen F, Sims D, Brettin T, Kuske C, Detter JC, Han C, Lapidus A, Copeland A, Glavina Del Rio T, Nolan M, Lucas S, Tice H, Cheng JF, Bruce D, Goodwin L, Pitluck S, Ovchinnikova G, Pati A, Ivanova N, Chen A, Palaniappan K, Chain P, D'haeseleer P, Goker M, Bristow J, Eisen JA, Markowitz V, Hugenholtz P, Rohde M, Klenk HP, Kyrpides NC | Stand Genomic Sci | 10.4056/sigs.12260 | 2009 | |
| Metabolism | Degradation of arginine by Slackia exigua ATCC 700122 and Cryptobacterium curtum ATCC 700683. | Uematsu H, Sato N, Djais A, Hoshino E | Oral Microbiol Immunol | 10.1111/j.1399-302X.2006.00307.x | 2006 | |
| Phylogeny | Umbribacter vaginalis gen. nov., sp. nov.: novel bacterium isolated from the human vagina. | Srinivasan S, Strenk SM, Beamer MA, Fiedler TL, Proll S, Acevedo-Oquendo GR, Bonura GM, Nagana Gowda GA, Raftery D, Hillier SL, Fredricks DN. | Int J Syst Evol Microbiol | 10.1099/ijsem.0.006931 | 2025 | |
| Phylogeny | Hugonella massiliensis gen. nov., sp. nov., genome sequence, and description of a new strictly anaerobic bacterium isolated from the human gut. | Elsawi Z, Togo AH, Beye M, Dubourg G, Andrieu C, Armsrtong N, Richez M, di Pinto F, Bittar F, Labas N, Fournier PE, Raoult D, Khelaifia S. | Microbiologyopen | 10.1002/mbo3.458 | 2017 | |
| Phylogeny | Cryptobacterium curtum gen. nov., sp. nov., a new genus of gram-positive anaerobic rod isolated from human oral cavities. | Nakazawa F, Poco SE, Ikeda T, Sato M, Kalfas S, Sundqvist G, Hoshino E | Int J Syst Bacteriol | 10.1099/00207713-49-3-1193 | 1999 | |
How to citeIf you want to cite this particular strain cite the following doi:
https://doi.org/10.13145/bacdive3053.20251217.10
When using BacDive for research please cite the following paper
BacDive in 2025: the core database for prokaryotic strain data
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