Fannyhessea vaginae DSM 15829 is an anaerobe, mesophilic, Gram-positive prokaryote that was isolated from human vaginal flora, healthy person.
Gram-positive coccus-shaped anaerobe mesophilic genome sequence 16S sequence| @ref 20215 |
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| Domain Bacteria |
| Phylum Actinomycetota |
| Class Coriobacteriia |
| Order Coriobacteriales |
| Family Atopobiaceae |
| Genus Fannyhessea |
| Species Fannyhessea vaginae |
| Full scientific name Fannyhessea vaginae (Rodriguez Jovita et al. 1999) Nouioui et al. 2018 |
| Synonyms (1) |
| BacDive ID | Other strains from Fannyhessea vaginae (10) | Type strain |
|---|---|---|
| 138335 | F. vaginae NN037.01, CIP 106319, CCUG 44156 | |
| 138349 | F. vaginae CIP 106430, CCUG 42099 | |
| 150247 | F. vaginae CCUG 39382 | |
| 151018 | F. vaginae CCUG 43049 | |
| 151419 | F. vaginae CCUG 44061 | |
| 151471 | F. vaginae CCUG 44116 | |
| 151476 | F. vaginae CCUG 44125 | |
| 151540 | F. vaginae CCUG 44258 | |
| 153113 | F. vaginae CCUG 48515 | |
| 154797 | F. vaginae CCUG 55227 |
| @ref | Name | Growth | Medium link | Composition | |
|---|---|---|---|---|---|
| 6041 | CHOPPED MEAT MEDIUM WITH CARBOHYDRATES (DSMZ Medium 110) | Medium recipe at MediaDive | Name: CHOPPED MEAT MEDIUM WITH CARBOHYDRATES (DSMZ Medium 110) Composition: Ground beef 500.0 g/l Casitone 30.0 g/l Agar 15.0 g/l K2HPO4 5.0 g/l Yeast extract 5.0 g/l D-Glucose 4.0 g/l Starch 1.0 g/l Maltose 1.0 g/l Cellobiose 1.0 g/l L-Cysteine HCl 0.5 g/l Ethanol 0.19 g/l Vitamin K3 0.05 g/l Hemin 0.005 g/l Sodium resazurin 0.0005 g/l Vitamin K1 NaOH Distilled water | ||
| 23097 | Columbia CNA agar (Difco) | supplemented with 5% horse blood | |||
| 36590 | MEDIUM 6 - Columbia agar with 10 % horse blood | Distilled water make up to (1000.000 ml);Columbia agar (39.000 g);Horseblood (100.000 ml) | |||
| 6041 | PYG MEDIUM (MODIFIED) (DSMZ Medium 104) | Medium recipe at MediaDive | Name: PYG MEDIUM (modified) (DSMZ Medium 104) Composition: Yeast extract 10.0 g/l Peptone 5.0 g/l Trypticase peptone 5.0 g/l Beef extract 5.0 g/l Glucose 5.0 g/l L-Cysteine HCl x H2O 0.5 g/l NaHCO3 0.4 g/l NaCl 0.08 g/l K2HPO4 0.04 g/l KH2PO4 0.04 g/l MgSO4 x 7 H2O 0.02 g/l CaCl2 x 2 H2O 0.01 g/l Hemin 0.005 g/l Ethanol 0.0038 g/l Resazurin 0.001 g/l Tween 80 Vitamin K1 NaOH Distilled water | ||
| 123775 | CIP Medium 6 | Medium recipe at CIP | |||
| 123775 | CIP Medium 6-Boites-Biorad | Medium recipe at CIP | |||
| 6041 | COLUMBIA BLOOD MEDIUM (DSMZ Medium 693) | Medium recipe at MediaDive | Name: COLUMBIA BLOOD MEDIUM (DSMZ Medium 693) Composition: Defibrinated sheep blood 50.0 g/l Columbia agar base |
| @ref | Spore formation | Confidence | |
|---|---|---|---|
| 125439 | 100 |
| @ref | Salt | Growth | Tested relation | Concentration | |
|---|---|---|---|---|---|
| 123775 | NaCl | growth | 6.5 % |
| @ref | Chebi-ID | Metabolite | Utilization activity | Kind of utilization tested | |
|---|---|---|---|---|---|
| 23097 | 4853 ChEBI | esculin | - | hydrolysis | |
| 123775 | 4853 ChEBI | esculin | - | hydrolysis | |
| 23097 | 5291 ChEBI | gelatin | - | hydrolysis | |
| 123775 | 606565 ChEBI | hippurate | - | hydrolysis | |
| 68380 | 29985 ChEBI | L-glutamate | - | degradation | from API rID32A |
| 23097 | 37684 ChEBI | mannose | - | builds acid from | |
| 23097 | 17632 ChEBI | nitrate | - | reduction | |
| 68380 | 17632 ChEBI | nitrate | - | reduction | from API rID32A |
| 123775 | 17632 ChEBI | nitrate | - | reduction | |
| 123775 | 16301 ChEBI | nitrite | - | reduction | |
| 23097 | 16634 ChEBI | raffinose | - | builds acid from | |
| 68380 | 16634 ChEBI | raffinose | - | fermentation | from API rID32A |
| 68380 | 27897 ChEBI | tryptophan | - | energy source | from API rID32A |
| 68380 | 16199 ChEBI | urea | - | hydrolysis | from API rID32A |
| @ref | Value | Activity | Ec | |
|---|---|---|---|---|
| 23097 | 6-phospho-beta-galactosidase | - | 3.2.1.85 | |
| 23097 | acid phosphatase | + | 3.1.3.2 | |
| 68382 | acid phosphatase | + | 3.1.3.2 | from API zym |
| 23097 | alanine arylamidase | - | 3.4.11.2 | |
| 123775 | alcohol dehydrogenase | - | 1.1.1.1 | |
| 68382 | alkaline phosphatase | - | 3.1.3.1 | from API zym |
| 23097 | alpha-arabinosidase | - | 3.2.1.55 | |
| 68380 | alpha-arabinosidase | - | 3.2.1.55 | from API rID32A |
| 23097 | alpha-chymotrypsin | - | 3.4.21.1 | |
| 68382 | alpha-chymotrypsin | - | 3.4.21.1 | from API zym |
| 23097 | alpha-fucosidase | - | 3.2.1.51 | |
| 68382 | alpha-fucosidase | - | 3.2.1.51 | from API zym |
| 68380 | alpha-fucosidase | - | 3.2.1.51 | from API rID32A |
| 23097 | alpha-galactosidase | - | 3.2.1.22 | |
| 68382 | alpha-galactosidase | - | 3.2.1.22 | from API zym |
| 68380 | alpha-galactosidase | - | 3.2.1.22 | from API rID32A |
| 23097 | alpha-glucosidase | - | 3.2.1.20 | |
| 68380 | alpha-glucosidase | - | 3.2.1.20 | from API rID32A |
| 23097 | alpha-mannosidase | - | 3.2.1.24 | |
| 68382 | alpha-mannosidase | - | 3.2.1.24 | from API zym |
| 23097 | arginine arylamidase | + | ||
| 23097 | arginine dihydrolase | + | 3.5.3.6 | |
| 23097 | beta-galactosidase | - | 3.2.1.23 | |
| 68382 | beta-galactosidase | - | 3.2.1.23 | from API zym |
| 123775 | beta-galactosidase | - | 3.2.1.23 | |
| 68380 | beta-galactosidase | - | 3.2.1.23 | from API rID32A |
| 68380 | beta-Galactosidase 6-phosphate | - | from API rID32A | |
| 23097 | beta-glucosidase | - | 3.2.1.21 | |
| 68382 | beta-glucosidase | - | 3.2.1.21 | from API zym |
| 68380 | beta-glucosidase | - | 3.2.1.21 | from API rID32A |
| 23097 | beta-glucuronidase | - | 3.2.1.31 | |
| 68382 | beta-glucuronidase | - | 3.2.1.31 | from API zym |
| 68380 | beta-glucuronidase | - | 3.2.1.31 | from API rID32A |
| 123775 | catalase | + | 1.11.1.6 | |
| 23097 | cystine arylamidase | - | 3.4.11.3 | |
| 68382 | cystine arylamidase | - | 3.4.11.3 | from API zym |
| 23097 | esterase (C 4) | - | ||
| 68382 | esterase (C 4) | + | from API zym | |
| 23097 | esterase lipase (C 8) | - | ||
| 123775 | gamma-glutamyltransferase | - | 2.3.2.2 | |
| 23097 | glutamate decarboxylase | - | 4.1.1.15 | |
| 68380 | glutamate decarboxylase | - | 4.1.1.15 | from API rID32A |
| 23097 | glutamyl-glutamate arylamidase | - | ||
| 68380 | glutamyl-glutamate arylamidase | - | from API rID32A | |
| 23097 | glycin arylamidase | + | ||
| 23097 | histidine arylamidase | + | ||
| 68380 | L-arginine arylamidase | + | from API rID32A | |
| 23097 | leucine arylamidase | + | 3.4.11.1 | |
| 68382 | leucine arylamidase | + | 3.4.11.1 | from API zym |
| 23097 | lipase (C 14) | - | ||
| 68382 | lipase (C 14) | - | from API zym | |
| 123775 | lysine decarboxylase | - | 4.1.1.18 | |
| 23097 | N-acetyl-beta-glucosaminidase | - | 3.2.1.52 | |
| 68382 | N-acetyl-beta-glucosaminidase | - | 3.2.1.52 | from API zym |
| 68380 | N-acetyl-beta-glucosaminidase | - | 3.2.1.52 | from API rID32A |
| 68382 | naphthol-AS-BI-phosphohydrolase | + | from API zym | |
| 123775 | ornithine decarboxylase | - | 4.1.1.17 | |
| 123775 | oxidase | - | ||
| 23097 | phenylalanine arylamidase | + | ||
| 23097 | proline-arylamidase | + | 3.4.11.5 | |
| 68380 | proline-arylamidase | + | 3.4.11.5 | from API rID32A |
| 23097 | pyroglutamic acid arylamidase | - | ||
| 68380 | pyrrolidonyl arylamidase | - | 3.4.19.3 | from API rID32A |
| 23097 | serine arylamidase | + | ||
| 23097 | trypsin | - | 3.4.21.4 | |
| 68382 | trypsin | - | 3.4.21.4 | from API zym |
| 68380 | tryptophan deaminase | - | 4.1.99.1 | from API rID32A |
| 23097 | tyrosine arylamidase | - | ||
| 23097 | urease | - | 3.5.1.5 | |
| 68380 | urease | - | 3.5.1.5 | from API rID32A |
| 68382 | valine arylamidase | - | from API zym |
| @ref | URE | ADH (Arg) | alpha GAL | beta GAL | beta-Galactosidase 6-phosphatebeta GP | alpha GLU | beta GLU | alpha ARA | beta GUR | beta-N-Acetyl-beta-glucosaminidasebeta NAG | MNE | RAF | GDC | alpha FUC | Reduction of nitrateNIT | IND | PAL | L-arginine arylamidaseArgA | ProA | LGA | Phenylalanine arylamidasePheA | Leucine arylamidaseLeuA | PyrA | Tyrosine arylamidaseTyrA | Alanine arylamidaseAlaA | Glycin arylamidaseGlyA | Histidine arylamidaseHisA | Glutamyl-glutamate arylamidaseGGA | Serine arylamidaseSerA | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 6041 | - | + | - | - | - | - | - | - | - | - | + | - | - | - | - | - | - | + | + | + | + | + | - | + | + | + | + | - | + | |
| 6041 | - | + | - | - | - | - | - | - | - | - | + | - | - | - | - | - | - | + | + | +/- | +/- | + | - | + | - | + | + | - | +/- | |
| 6041 | - | - | - | - | - | - | - | - | - | - | +/- | - | - | - | - | - | - | + | + | - | - | +/- | - | - | - | - | - | - | - | |
| 6041 | - | +/- | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | + | + | +/- | +/- | + | - | +/- | - | +/- | +/- | - | - | |
| 6041 | - | + | - | - | - | - | - | - | - | - | + | - | - | - | - | - | - | + | + | - | - | + | - | - | - | - | - | - | - | |
| 54577 | - | + | - | - | - | - | - | - | - | - | - | - | - | - | - | - | + | + | + | + | + | + | - | + | + | + | + | - | + |
| @ref | Sample type | Geographic location | Country | Country ISO 3 Code | Continent | Latitude | Longitude | Sampling date | Isolation date | |
|---|---|---|---|---|---|---|---|---|---|---|
| 6041 | human vaginal flora, healthy person | Göteborg | Sweden | SWE | Europe | 57.7089 | 11.9746 57.7089/11.9746 | |||
| 54577 | Human vaginal flora,healthy person | Göteborg | Sweden | SWE | Europe | 1998-01-01 | ||||
| 67771 | From human vaginal flora, healthy person | Goteborg | Sweden | SWE | Europe | |||||
| 123775 | Human, Vaginal flora | Göteborg | Sweden | SWE | Europe | 1998 |
Global distribution of 16S sequence Y17195 (>99% sequence identity) for Fannyhessea vaginae from Microbeatlas ![]()
| @ref | Description | Assembly level | INSDC accession | BV-BRC accession | IMG accession | NCBI tax ID | Score | |
|---|---|---|---|---|---|---|---|---|
| 124043 | ASM1602657v1 assembly for Fannyhessea vaginae FDAARGOS_934 | complete | 82135 | 99.25 | ||||
| 66792 | ASM15923v2 assembly for Fannyhessea vaginae DSM 15829 | contig | 525256 | 78.2 | ||||
| 66792 | ASM17833v1 assembly for Fannyhessea vaginae DSM 15829 | scaffold | 525256 | 67.79 |
| Topic | Title | Authors | Journal | DOI | Year | |
|---|---|---|---|---|---|---|
| In vitro bacterial vaginosis biofilm community manipulation using endolysin therapy. | Johnston W, Ware A, Kuiters WF, Delaney C, Brown JL, Hagen S, Corcoran D, Cummings M, Ramage G, Kean R. | Biofilm | 10.1016/j.bioflm.2022.100101 | 2023 | ||
| In Vitro Bactericidal Activity of a Neomycin-Polymyxin B-Nystatin Combination Compared to Metronidazole and Clindamycin Against the Main Bacteria Involved in Bacterial Vaginosis and Aerobic Vaginitis. | Feuillolay C, Salvatico S, Escola J, Quioc-Salomon B, Carrois F, Roques C. | Pharmaceuticals (Basel) | 10.3390/ph18030340 | 2025 | ||
| Metabolism | Interleukin-36gamma Is Elevated in Cervicovaginal Epithelial Cells in Women With Bacterial Vaginosis and In Vitro After Infection With Microbes Associated With Bacterial Vaginosis. | Gardner JK, Laniewski P, Knight A, Haddad LB, Swaims-Kohlmeier A, Herbst-Kralovetz MM. | J Infect Dis | 10.1093/infdis/jiz514 | 2020 | |
| Pathogenicity | Novel Selective Inhibition of Lactobacillus iners by Lactobacillus-Derived Bacteriocins. | Nilsen T, Swedek I, Lagenaur LA, Parks TP. | Appl Environ Microbiol | 10.1128/aem.01594-20 | 2020 | |
| HPV infection alters vaginal microbiome through down-regulating host mucosal innate peptides used by Lactobacilli as amino acid sources. | Lebeau A, Bruyere D, Roncarati P, Peixoto P, Hervouet E, Cobraiville G, Taminiau B, Masson M, Gallego C, Mazzucchelli G, Smargiasso N, Fleron M, Baiwir D, Hendrick E, Pilard C, Lerho T, Reynders C, Ancion M, Greimers R, Twizere JC, Daube G, Schlecht-Louf G, Bachelerie F, Combes JD, Melin P, Fillet M, Delvenne P, Hubert P, Herfs M. | Nat Commun | 10.1038/s41467-022-28724-8 | 2022 | ||
| Pathogenicity | Efficacy of rifaximin vaginal tablets in treatment of bacterial vaginosis: a molecular characterization of the vaginal microbiota. | Cruciani F, Brigidi P, Calanni F, Lauro V, Tacchi R, Donders G, Peters K, Guaschino S, Vitali B. | Antimicrob Agents Chemother | 10.1128/aac.00061-12 | 2012 | |
| Adaptation of key bacterial vaginosis-associated bacteria to a medium simulating genital tract secretions: a transcriptomic analysis. | Sousa LGV, Franca A, Pinheiro V, Muzny CA, Cerca N. | Front Genet | 10.3389/fgene.2025.1552307 | 2025 | ||
| Transcriptome | Gardnerella vaginalis, Fannyhessea vaginae, and Prevotella bivia Strongly Influence Each Other's Transcriptome in Triple-Species Biofilms. | Sousa LGV, Novak J, Franca A, Muzny CA, Cerca N. | Microb Ecol | 10.1007/s00248-024-02433-9 | 2024 | |
| Optimized bacterial absolute quantification method by qPCR using an exogenous bacterial culture as a normalization strategy in triple-species BV-like biofilms. | Lameira I, Pinto AS, Lima A, Muzny CA, Cerca N. | J Microbiol Methods | 10.1016/j.mimet.2024.106895 | 2024 | ||
| A New PNA-FISH Probe Targeting Fannyhessea vaginae. | Sousa LGV, Castro J, Franca A, Almeida C, Muzny CA, Cerca N. | Front Cell Infect Microbiol | 10.3389/fcimb.2021.779376 | 2021 | ||
| Development of a Prevotella bivia PNA probe and a multiplex approach to detect three relevant species in bacterial vaginosis-associated biofilms. | Sousa LGV, Almeida C, Muzny CA, Cerca N. | NPJ Biofilms Microbiomes | 10.1038/s41522-023-00411-6 | 2023 | ||
| Key bacterial vaginosis-associated bacteria influence each other's growth in biofilms in rich media and media simulating vaginal tract secretions. | Sousa LGV, Muzny CA, Cerca N. | Biofilm | 10.1016/j.bioflm.2024.100247 | 2025 | ||
| Six Bacterial Vaginosis-Associated Species Can Form an In Vitro and Ex Vivo Polymicrobial Biofilm That Is Susceptible to Thymbra capitata Essential Oil. | Rosca AS, Castro J, Sousa LGV, Franca A, Cavaleiro C, Salgueiro L, Cerca N. | Front Cell Infect Microbiol | 10.3389/fcimb.2022.824860 | 2022 | ||
| Altered Innate Immunity and Damaged Epithelial Integrity in Vaginal Microbial Dysbiosis. | Cheu RK, Mohammadi A, Schifanella L, Broedlow C, Driscoll CB, Miller CJ, Reeves RK, Yudin MH, Hensley-McBain T, Kaul R, Klatt NR. | Front Reprod Health | 10.3389/frph.2022.876729 | 2022 | ||
| A novel Gardnerella, Prevotella, and Lactobacillus standard that improves accuracy in quantifying bacterial burden in vaginal microbial communities. | Elnaggar JH, Ardizzone CM, Cerca N, Toh E, Laniewski P, Lillis RA, Herbst-Kralovetz MM, Quayle AJ, Muzny CA, Taylor CM. | Front Cell Infect Microbiol | 10.3389/fcimb.2023.1198113 | 2023 | ||
| Bacterial vaginosis and health-associated bacteria modulate the immunometabolic landscape in 3D model of human cervix. | Laniewski P, Herbst-Kralovetz MM. | NPJ Biofilms Microbiomes | 10.1038/s41522-021-00259-8 | 2021 | ||
| Genetics | Genome-Based Taxonomic Classification of the Phylum Actinobacteria. | Nouioui I, Carro L, Garcia-Lopez M, Meier-Kolthoff JP, Woyke T, Kyrpides NC, Pukall R, Klenk HP, Goodfellow M, Goker M. | Front Microbiol | 10.3389/fmicb.2018.02007 | 2018 | |
| Antimicrobial Evaluation and Fraction-Based Profiling of Basil Essential Oil Against Vaginal Pathogens. | Park M, Park J, Hwang DY, Park S, Lee H. | Antioxidants (Basel) | 10.3390/antiox14060628 | 2025 | ||
| Phylogeny | Characterization of a novel Atopobium isolate from the human vagina: description of Atopobium vaginae sp. nov. | Rodriguez Jovita M, Collins MD, Sjoden B, Falsen E | Int J Syst Bacteriol | 10.1099/00207713-49-4-1573 | 1999 |
| #6041 | Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 15829 |
| #20215 | Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 ) |
| #20218 | Verslyppe, B., De Smet, W., De Baets, B., De Vos, P., Dawyndt P.: StrainInfo introduces electronic passports for microorganisms.. Syst Appl Microbiol. 37: 42 - 50 2014 ( DOI 10.1016/j.syapm.2013.11.002 , PubMed 24321274 ) |
| #23097 | Mar Rodriguez Jovita,Matthew D. Collins,Berit Sjödén,Enevold Falsen: Characterization of a novel Atopobium isolate from the human vagina: description of Atopobium vaginae sp. nov.. IJSEM 49: 1573 - 1576 1999 ( DOI 10.1099/00207713-49-4-1573 , PubMed 10555338 ) |
| #36590 | ; Curators of the CIP; |
| #54577 | Culture Collection University of Gothenburg (CCUG) ; Curators of the CCUG; CCUG 38953 |
| #66792 | Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) . |
| #67771 | Korean Collection for Type Cultures (KCTC) ; Curators of the KCTC; |
| #68380 | Automatically annotated from API rID32A . |
| #68382 | Automatically annotated from API zym . |
| #69479 | João F Matias Rodrigues, Janko Tackmann,Gregor Rot, Thomas SB Schmidt, Lukas Malfertheiner, Mihai Danaila,Marija Dmitrijeva, Daniela Gaio, Nicolas Näpflin and Christian von Mering. University of Zurich.: MicrobeAtlas 1.0 beta . |
| #123775 | Collection of Institut Pasteur ; Curators of the CIP; CIP 106431 |
| #124043 | Isabel Schober, Julia Koblitz: Data extracted from sequence databases, automatically matched based on designation and taxonomy . |
| #125439 | Philipp Münch, René Mreches, Martin Binder, Hüseyin Anil Gündüz, Xiao-Yin To, Alice McHardy: deepG: Deep Learning for Genome Sequence Data. R package version 0.3.1 . |
| #126262 | A. Lissin, I. Schober, J. F. Witte, H. Lüken, A. Podstawka, J. Koblitz, B. Bunk, P. Dawyndt, P. Vandamme, P. de Vos, J. Overmann, L. C. Reimer: StrainInfo—the central database for linked microbial strain identifiers. ( DOI 10.1093/database/baaf059 ) |
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