Clostridium chauvoei (DSM 7528, ATCC 10092, NCIMB 10665)

Name: Clostridium chauvoei (DSM 7528, ATCC 10092, NCIMB 10665)
Creator: BacDive
License: http://creativecommons.org/licenses/by/4.0/

BacDive ID 2769

Type strain

Strain Designation 2585, 10123

Culture col. no. DSM 7528 ATCC 10092 NCIMB 10665 2585 CIP 104317 1 more

NCBI tax ID(s) 46867

Special Collections DSMZ CIP

History DSMZ <- ATCC <- C.D. Stein, 2585 CIP <- 1994, J.P. Carlier, Inst. Pasteur, Paris, France: strain 10123 <- ATCC <- C.D. Stein: strain 2585

Links

Clostridium chauvoei 2585 is an anaerobe, Gram-positive, rod-shaped human pathogen that was isolated from bovine blackleg.

Gram-positive rod-shaped anaerobe human pathogen genome sequence 16S sequence Bacteria

Name and taxonomic classification

SI-ID 35178

ATCC 10092,CIP 104317,DSM 7528,NCIMB 10665,BCRC 14544,CCRC 14544,NCTC 13023

@ref 20215

Last LPSN update 2026-05-29 08:25:33

Domain Bacteria

Phylum Bacillota

Class Clostridia

Order Eubacteriales

Family Clostridiaceae

Genus Clostridium

Species Clostridium chauvoei

Full scientific name Clostridium chauvoei (Arloing et al. 1887) Scott 1928 (Approved Lists 1980)

Synonyms (1)

"Bacterium chauvoei"

BacDive ID	Other strains from **Clostridium chauvoei** (2)	Type strain
137112	C. chauvoei Vallée, CIP 60.33
141462	C. chauvoei CCUG 2039, ATCC 19399, NCTC 8070, CECT 4108

Morphology

Cell morphology

@ref	Gram stain	Cell shape	Motility
118226	positive	rod-shaped

Culture and growth conditions

Culture medium

@ref	Name	Medium link	Composition
3203	RCM MEDIUM (DSMZ Medium 634)	Medium recipe at MediaDive	Name: RCM MEDIUM (DSMZ Medium 634) Composition: Sodium resazurin 0.0005 g/l dehydrated RCM medium
37173	MEDIUM 20 - for Anaerobic bacteria		Agar (15.000 g);Glucose (5.000 g);Yeast extract (20.000 g);Tryptone (30.000 g);Cysteine hydrochloride (0.500 g);distilled water (1000.000 ml);Hemin solution -M00149 (25.000 ml)
118226	CIP Medium 20	Medium recipe at CIP
118226	CIP Medium 187	Medium recipe at CIP

Culture temp

@ref	Growth	Type	Temperature (°C)
3203	positive	growth	37
37173	positive	growth	37

Physiology and metabolism

Oxygen tolerance

@ref	Oxygen tolerance	Confidence
3203	anaerobe
125439	anaerobe	99.76

Metabolite utilization

@ref	Chebi-ID	Metabolite	Utilization activity	Kind of utilization tested
118226	17632 ChEBI	nitrate	-	reduction
118226	16301 ChEBI	nitrite	-	reduction

Metabolite production

@ref	Chebi-ID	Metabolite	Production
118226	35581 ChEBI	indole

Enzymes

@ref	Value	Activity	Ec
68382	acid phosphatase	-	3.1.3.2	from API zym
68382	alkaline phosphatase	-	3.1.3.1	from API zym
68382	alpha-chymotrypsin	-	3.4.21.1	from API zym
68382	alpha-fucosidase	-	3.2.1.51	from API zym
68382	alpha-galactosidase	-	3.2.1.22	from API zym
68382	alpha-glucosidase	-	3.2.1.20	from API zym
68382	alpha-mannosidase	-	3.2.1.24	from API zym
68382	beta-galactosidase	-	3.2.1.23	from API zym
68382	beta-glucosidase	-	3.2.1.21	from API zym
68382	beta-glucuronidase	-	3.2.1.31	from API zym
118226	catalase	-	1.11.1.6
68382	cystine arylamidase	-	3.4.11.3	from API zym
68382	esterase (C 4)	-		from API zym
68382	esterase lipase (C 8)	-		from API zym
68382	leucine arylamidase	-	3.4.11.1	from API zym
68382	lipase (C 14)	-		from API zym
68382	N-acetyl-beta-glucosaminidase	-	3.2.1.52	from API zym
68382	naphthol-AS-BI-phosphohydrolase	+		from API zym
118226	oxidase	-
68382	trypsin	-	3.4.21.4	from API zym
118226	urease	-	3.5.1.5
68382	valine arylamidase	-		from API zym

API zym

@ref	Control	Alkaline phosphatase	Esterase (C 4)	2-naphtyl caprylateEsterase Lipase (C 8)	Lipase (C 14)	L-leucyl-2-naphthylamideLeucine arylamidase	L-valyl-2-naphthylamideValine arylamidase	L-cystyl-2-naphthylamideCystine arylamidase	Trypsin	alpha- Chymotrypsin	Acid phosphatase	Naphthol-AS-BI-phosphateNaphthol-AS-BI-phosphohydrolase	alpha- Galactosidase	beta- Galactosidase	beta- Glucuronidase	alpha- Glucosidase	beta- Glucosidase	N-acetyl-beta- glucosaminidase	alpha- Mannosidase	alpha- Fucosidase
118226	-	-	-	-	-	-	-	-	-	-	-	+	-	-	-	-	-	-	-	-

Isolation, sampling and environmental information

Isolation source categories

Cat1	Cat2	Cat3
#Infection	#Disease	-
#Host	#Mammals	#Bovinae (Cow, Cattle)

Isolation

@ref	Sample type
3203	bovine blackleg
118226	Animal, Bovine, black leg

Taxonmaps

69479

Global distribution of 16S sequence U51843 (>99% sequence identity) for Clostridium from Microbeatlas

Aquatic Samples	3525
Soil Samples	5709
Animal Samples	41305
Plant Samples	744
Total Samples	51283

Interaction and safety

Risk assessment

@ref	Pathogenicity human	Pathogenicity animal	Biosafety level	Biosafety level comment
3203			2	Risk group (German classification) According to TRBA 466
118226			2	Risk group (French classification) According to TRBA 466

Sequence information

Genome sequences

@ref	Description	Assembly level	INSDC accession	BV-BRC accession	IMG accession	NCBI tax ID	Score
66792	ASM232720v1 assembly for Clostridium chauvoei 12S0467	complete	GCA_002327205	46867.40	2775507064	46867	99.07
66792	ASM232718v1 assembly for Clostridium chauvoei DSM 7528	complete	GCA_002327185	46867.39	2775507063	46867	98.35

16S sequences

@ref	Description	Accession	Length	NCBI tax ID
20218	Clostridium chauvoei DNA, 16S-23S rRNA spacer region	AB040540	286	46867
20218	Clostridium chauvoei DNA, 16S-23S rRNA spacer region	AB040541	363	46867
20218	Clostridium chauvoei DNA, 16S-23S rRNA spacer region	AB040542	441	46867
20218	Clostridium chauvoei genes for 16S rRNA, 16S-23S rRNA spacer region (rrn1), 23S rRNA, partial sequence	AB040712	324	46867
20218	Clostridium chauvoei genes for 16S rRNA, tRNA-Ile, 23S rRNA, partial and complete sequence	AB040713	401	46867
20218	Clostridium chauvoei genes for 16S rRNA, tRNA-Ala, tRNA-Ile, 23S rRNA, partial and complete sequence	AB040714	479	46867
3203	Clostridium chauvoei 16S ribosomal RNA gene sequence	U51843	1507	46867

Genome-based predictions

Predictions

Predictions from Deep Learning for Genome Sequence Data. R package version 0.3.1 based on: ASM232720v1 assembly for Clostridium chauvoei 12S0467
NCBI: GCA_002327205

@ref	Trait	Model	Prediction	Confidence in %	In training data
125439	oxygen_tolerance	BacteriaNetⓘ	anaerobe	99.76	no
125439	gram_stain	BacteriaNetⓘ	positive	71.43	no
125439	motility	BacteriaNetⓘ	yes	83.15	no
125439	spore_formation	BacteriaNetⓘ	yes	87.81	no

Predictions from bacterial phenotypic traits through improved machine learning using high-quality, curated datasets based on: Clostridium chauvoei DSM 7528
NCBI: GCA_002327185.1

@ref	Trait	Model	Prediction	Confidence in %	In training data
125438	gram-positive	gram-positiveⓘ	yes	69.91	no
125438	anaerobic	anaerobicⓘ	yes	87.89	yes
125438	aerobic	aerobicⓘ	no	97.69	yes
125438	spore-forming	spore-formingⓘ	yes	73.06	no
125438	thermophilic	thermophileⓘ	no	88.16	no
125438	flagellated	motile2+ⓘ	yes	77.92	no

Literature

Topic	Title	Authors	Journal	DOI	Year
	Blackleg in cattle in Kazakhstan: regional epizootology, seasonal patterns, and molecular identification of the pathogen.	Mussoyev A, Abutalip A, Nurpeisova A, Suchshikh V, Makulbekov Y, Yoo HS, Adambayeva A, Kalkabayev K, Rametov N, Kassenov M, Abay Z.	Front Vet Sci	10.3389/fvets.2025.1680881	2025
	Computational Design of a Multi-epitope Vaccine Against Clostridium chauvoei: An Immunoinformatics Approach.	Yilmaz Colak C.	Int J Pept Res Ther	10.1007/s10989-021-10279-9	2021
Genetics	First Comparative Analysis of Clostridium septicum Genomes Provides Insights Into the Taxonomy, Species Genetic Diversity, and Virulence Related to Gas Gangrene.	Thomas P, Abdel-Glil MY, Subbaiyan A, Busch A, Eichhorn I, Wieler LH, Neubauer H, Pletz M, Seyboldt C.	Front Microbiol	10.3389/fmicb.2021.771945	2021
Phylogeny	Comparison of intestinal permeability, morphology, and ileal microbial communities of commercial hens housed in conventional cages and cage-free housing systems.	Wiersema ML, Koester LR, Schmitz-Esser S, Koltes DA.	Poult Sci	10.1016/j.psj.2020.10.052	2021
	A simple cost-effective method for purification of Clostridium chauvoei cell-surface proteins for detection of antibodies against blackleg disease vaccine.	Adib N, Zahmatkesh A, Bagheri M.	Vet Res Forum	10.30466/vrf.2024.2023812.4190	2025
	Blackleg: A deadly disease with a hidden cause.	Tyasningsih W, Khairullah AR, Tang JYH, Effendi MH, Rehman S, Ma'ruf IF, Wardhani BWK, Moses IB, Budiastuti B, Fauzia KA, Ahmad RZ, Fauziah I, Kusala MKJ, Pratama BP, Kurniasih DAA, Wibowo S.	Open Vet J	10.5455/ovj.2025.v15.i6.7	2025
Pathogenicity	Blackleg: A Review of the Agent and Management of the Disease in Brazil.	Sousa AIJ, Galvao CC, Pires PS, Salvarani FM.	Animals (Basel)	10.3390/ani14040638	2024
	Genomic comparison of Clostridium chauvoei isolates from classical and visceral clinical manifestation.	Ziech RE, Siqueira FM, Cibulski S, De Carli S, Dos Santos HF, Fighera RA, Frey J, de Vargas AC.	Braz J Microbiol	10.1007/s42770-019-00177-0	2020
Phylogeny	Human fulminant gas gangrene caused by Clostridium chauvoei.	Nagano N, Isomine S, Kato H, Sasaki Y, Takahashi M, Sakaida K, Nagano Y, Arakawa Y.	J Clin Microbiol	10.1128/jcm.01895-07	2008
Phylogeny	Novel real-time PCR assay for simultaneous detection and differentiation of Clostridium chauvoei and Clostridium septicum in clostridial myonecrosis.	Halm A, Wagner M, Kofer J, Hein I.	J Clin Microbiol	10.1128/jcm.01975-09	2010
Enzymology	Actin-specific ADP-ribosyltransferase produced by a Clostridium difficile strain.	Popoff MR, Rubin EJ, Gill DM, Boquet P.	Infect Immun	10.1128/iai.56.9.2299-2306.1988	1988
Enzymology	Cloning and sequence analysis of hyaluronoglucosaminidase (nagH) gene of Clostridium chauvoei.	Dangi SK, Yadav PK, Tiwari A, Nagaleekar VK	Vet World	10.14202/vetworld.2017.1104-1107	2017
Genetics	First report of two complete Clostridium chauvoei genome sequences and detailed in silico genome analysis.	Thomas P, Semmler T, Eichhorn I, Lubke-Becker A, Werckenthin C, Abdel-Glil MY, Wieler LH, Neubauer H, Seyboldt C	Infect Genet Evol	10.1016/j.meegid.2017.07.018	2017
Enzymology	Extracellular proteins of Clostridium chauvoei are protective in a mouse model.	Mattar MA, Cortinas TI, Stefanini AM	Acta Vet Hung	10.1556/AVet.55.2007.2.1	2007
Enzymology	[Deoxyribonuclease activity detection in Clostridium chauvoei strains].	Carloni GH, Bentancor LD, De Torres RA	Rev Argent Microbiol		2005
Phylogeny	Diversity in molecular mass of the common EDTA-soluble antigens of Clostridium chauvoei and Clostridium septicum.	Hamaoka T, Terakado N, Nakamura S	Microbiol Immunol	10.1111/j.1348-0421.1994.tb01756.x	1994

References

#3203	Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 7528
#20215	Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 )
#20218	Verslyppe, B., De Smet, W., De Baets, B., De Vos, P., Dawyndt P.: StrainInfo introduces electronic passports for microorganisms.. Syst Appl Microbiol. 37: 42 - 50 2014 ( DOI 10.1016/j.syapm.2013.11.002 , PubMed 24321274 )
#37173	; Curators of the CIP;
#66792	Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) .
#68382	Automatically annotated from API zym .
#69479	João F Matias Rodrigues, Janko Tackmann,Gregor Rot, Thomas SB Schmidt, Lukas Malfertheiner, Mihai Danaila,Marija Dmitrijeva, Daniela Gaio, Nicolas Näpflin and Christian von Mering. University of Zurich.: MicrobeAtlas 1.0 beta .
#118226	Collection of Institut Pasteur ; Curators of the CIP; CIP 104317
#125438	Julia Koblitz, Lorenz Christian Reimer, Rüdiger Pukall, Jörg Overmann: Predicting bacterial phenotypic traits through improved machine learning using high-quality, curated datasets. 2024 ( DOI 10.1101/2024.08.12.607695 )
#125439	Philipp Münch, René Mreches, Martin Binder, Hüseyin Anil Gündüz, Xiao-Yin To, Alice McHardy: deepG: Deep Learning for Genome Sequence Data. R package version 0.3.1 .
#126262	A. Lissin, I. Schober, J. F. Witte, H. Lüken, A. Podstawka, J. Koblitz, B. Bunk, P. Dawyndt, P. Vandamme, P. de Vos, J. Overmann, L. C. Reimer: StrainInfo—the central database for linked microbial strain identifiers. ( DOI 10.1093/database/baaf059 )

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Clostridium chauvoei (DSM 7528, ATCC 10092, NCIMB 10665)

Name and taxonomic classification

Morphology

Cell morphology

Culture and growth conditions

Culture medium

Culture temp

Physiology and metabolism

Oxygen tolerance

Metabolite utilization

Metabolite production

Enzymes

API zym

Isolation, sampling and environmental information

Isolation source categories

Isolation

Taxonmaps

Interaction and safety

Risk assessment

Sequence information

Genome sequences

Genome browser: GCA_002327205

16S sequences

Genome-based predictions

Predictions

Literature

Literature

References

BacDive

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