Clostridium scindens 19 is an anaerobe, mesophilic, Gram-positive prokaryote that was isolated from human faeces.
Gram-positive rod-shaped anaerobe mesophilic genome sequence 16S sequence| @ref 20215 |
|
Last LPSN update
2025-12-16 09:47:23 |
| Domain Bacillati |
| Phylum Bacillota |
| Class Clostridia |
| Order Eubacteriales |
| Family Clostridiaceae |
| Genus Clostridium |
| Species Clostridium scindens |
| Full scientific name Clostridium scindens Morris et al. 1985 |
| BacDive ID | Other strains from Clostridium scindens (7) | Type strain |
|---|---|---|
| 159178 | C. scindens BL-389-WT-3D, DSM 100975 | |
| 160948 | C. scindens JCM 10418, VPI 12708 | |
| 160949 | C. scindens JCM 10419 | |
| 160951 | C. scindens JCM 10420 | |
| 160952 | C. scindens JCM 10421 | |
| 160953 | C. scindens JCM 10422 | |
| 160954 | C. scindens JCM 10423 |
| @ref | Name | Growth | Medium link | Composition | |
|---|---|---|---|---|---|
| 2276 | WILKINS-CHALGREN ANAEROBE BROTH (DSMZ Medium 339) | Medium recipe at MediaDive  | Name: WILKINS-CHALGREN ANAEROBE BROTH (DSMZ Medium 339; with strain-specific modifications) Composition: dehydrated Wilkins-Chalgren medium 33.0 g/l D-Glucose 10.0 g/l L-Cysteine HCl 0.3 g/l Sodium resazurin 0.0005 g/l Distilled water | ||
| 2276 | CHOPPED MEAT MEDIUM WITH CARBOHYDRATES (DSMZ Medium 110) | Medium recipe at MediaDive | Name: CHOPPED MEAT MEDIUM WITH CARBOHYDRATES (DSMZ Medium 110) Composition: Ground beef 500.0 g/l Casitone 30.0 g/l Agar 15.0 g/l K2HPO4 5.0 g/l Yeast extract 5.0 g/l D-Glucose 4.0 g/l Starch 1.0 g/l Maltose 1.0 g/l Cellobiose 1.0 g/l L-Cysteine HCl 0.5 g/l Ethanol 0.19 g/l Vitamin K3 0.05 g/l Hemin 0.005 g/l Sodium resazurin 0.0005 g/l Vitamin K1 NaOH Distilled water | ||
| 122518 | CIP Medium 20 | Medium recipe at CIP |
| 122518 | Spore formationno |
| @ref | Value | Activity | Ec | |
|---|---|---|---|---|
| 68382 | acid phosphatase | + | 3.1.3.2 | from API zym |
| 68382 | alkaline phosphatase | - | 3.1.3.1 | from API zym |
| 68382 | alpha-chymotrypsin | - | 3.4.21.1 | from API zym |
| 68382 | alpha-fucosidase | - | 3.2.1.51 | from API zym |
| 68382 | alpha-galactosidase | - | 3.2.1.22 | from API zym |
| 68382 | alpha-glucosidase | - | 3.2.1.20 | from API zym |
| 68382 | alpha-mannosidase | - | 3.2.1.24 | from API zym |
| 122518 | amylase | - | ||
| 68382 | beta-galactosidase | - | 3.2.1.23 | from API zym |
| 122518 | beta-galactosidase | - | 3.2.1.23 | |
| 68382 | beta-glucosidase | - | 3.2.1.21 | from API zym |
| 68382 | beta-glucuronidase | - | 3.2.1.31 | from API zym |
| 122518 | caseinase | - | 3.4.21.50 | |
| 122518 | catalase | - | 1.11.1.6 | |
| 68382 | cystine arylamidase | - | 3.4.11.3 | from API zym |
| 68382 | esterase (C 4) | - | from API zym | |
| 68382 | esterase lipase (C 8) | - | from API zym | |
| 122518 | gelatinase | - | ||
| 68382 | leucine arylamidase | - | 3.4.11.1 | from API zym |
| 68382 | lipase (C 14) | - | from API zym | |
| 68382 | N-acetyl-beta-glucosaminidase | - | 3.2.1.52 | from API zym |
| 68382 | naphthol-AS-BI-phosphohydrolase | + | from API zym | |
| 122518 | oxidase | - | ||
| 68382 | trypsin | - | 3.4.21.4 | from API zym |
| 68382 | valine arylamidase | - | from API zym |
| Cat1 | Cat2 | Cat3 | |
|---|---|---|---|
| #Host | #Human | - | |
| #Host Body Product | #Gastrointestinal tract | #Feces (Stool) |
Global distribution of 16S sequence Y18186 (>99% sequence identity) for [Clostridium] scindens subclade from Microbeatlas 
 Aquatic Samples |
837 |
 Soil Samples |
346 |
 Animal Samples |
78797 |
 Plant Samples |
225 |
| Total Samples | 80205 |
| @ref | Description | Assembly level | INSDC accession | BV-BRC accession | IMG accession | NCBI tax ID | Score | |
|---|---|---|---|---|---|---|---|---|
| 66792 | ASM429512v1 assembly for [Clostridium] scindens ATCC 35704 | complete | GCA_004295125   | 411468.41  | 8002741647  | 411468 | 97.02 | |
| 67770 | ASM15450v1 assembly for [Clostridium] scindens ATCC 35704 | scaffold | GCA_000154505 | 411468.9 | 641736197 | 411468 | 65.08 |
| @ref | Description | Accession | Length | Database | NCBI tax ID | |
|---|---|---|---|---|---|---|
| 20218 | Clostridium scindens 16S rRNA gene, partial, strain DSM 5676 | Y18186 | 1490 |  | 29347 | |
| 20218 | Clostridium scindens 16S rRNA, partial sequence, strain:JCM 6567 | AB020883 | 1453 | | 29347 | |
| 20218 | Clostridium scindens gene for 16S ribosomal RNA, partial sequence | AB910747 | 1496 | | 29347 | |
| 2276 | Clostridium scindens 16S ribosomal RNA gene, partial sequence | AF262238 | 1529 | | 29347 |
| Topic | Title | Authors | Journal | DOI | Year | |
|---|---|---|---|---|---|---|
| Lactobacillus acidophilus potentiates oncolytic virotherapy through modulating gut microbiota homeostasis in hepatocellular carcinoma. | Zhang J, Yang J, Luo J, Wu W, Luo H, Wei W, Lyu H, Wang Y, Yi H, Zhang Y, Fan Z, Lyu H, Kanakaveti VP, Qin B, Yuan P, Yang R, Zhang H, Zuo T, Felsher DW, Lee MH, Li K. | Nat Commun | 10.1038/s41467-025-58407-z | 2025 | | |
| Clostridium scindens: history and current outlook for a keystone species in the mammalian gut involved in bile acid and steroid metabolism. | Daniel SL, Ridlon JM. | FEMS Microbiol Rev | 10.1093/femsre/fuaf016 | 2025 | | |
| Development of culture methods capable of culturing a wide range of predominant species of intestinal bacteria. | Hirano R, Nishita I, Nakai R, Bito A, Sasabe R, Kurihara S. | Front Cell Infect Microbiol | 10.3389/fcimb.2023.1056866 | 2023 | | |
| Carotenoid productivity in human intestinal bacteria Eubacterium limosum and Leuconostoc mesenteroides with functional analysis of their carotenoid biosynthesis genes. | Matsumoto W, Takemura M, Nanaura H, Ami Y, Maoka T, Shindo K, Kurihara S, Misawa N. | Eng Microbiol | 10.1016/j.engmic.2024.100147 | 2024 | | |
| Highly efficient CRISPR-Cas9 base editing in Bifidobacterium with bypass of restriction modification systems. | Lin H-C, Hsiao W-C, Hsu Y-C, Lin M-C, Hsu C-C, Zhang MM. | Appl Environ Microbiol | 10.1128/aem.01985-24 | 2025 | | |
| Clostridium scindens secretome suppresses virulence gene expression of Clostridioides difficile in a bile acid-independent manner. | Saenz C, Fang Q, Gnanasekaran T, Trammell SAJ, Buijink JDA, Pisano P, Wierer M, Moens F, Lengger B, Brejnrod A, Arumugam M. | Microbiol Spectr | 10.1128/spectrum.03933-22 | 2023 | | |
| Genetics | Probing the "Dark Matter" of the Human Gut Phageome: Culture Assisted Metagenomics Enables Rapid Discovery and Host-Linking for Novel Bacteriophages. | Fitzgerald CB, Shkoporov AN, Upadrasta A, Khokhlova EV, Ross RP, Hill C. | Front Cell Infect Microbiol | 10.3389/fcimb.2021.616918 | 2021 | |
| Enzymology | The microbiota-derived bile acid taurodeoxycholic acid improves hepatic cholesterol levels in mice with cancer cachexia. | Thibaut MM, Roumain M, Piron E, Gillard J, Loriot A, Neyrinck AM, Rodriguez J, Massart I, Thissen JP, Huot JR, Pin F, Bonetto A, Delzenne NM, Muccioli GG, Bindels LB. | Gut Microbes | 10.1080/19490976.2025.2449586 | 2025 | |
| Pathogenicity | Myxopyronin B inhibits growth of a Fidaxomicin-resistant Clostridioides difficile isolate and interferes with toxin synthesis. | Brauer M, Herrmann J, Zuhlke D, Muller R, Riedel K, Sievers S. | Gut Pathog | 10.1186/s13099-021-00475-9 | 2022 | |
| Dominant Bacterial Phyla from the Human Gut Show Widespread Ability To Transform and Conjugate Bile Acids. | Lucas LN, Barrett K, Kerby RL, Zhang Q, Cattaneo LE, Stevenson D, Rey FE, Amador-Noguez D. | mSystems | 10.1128/msystems.00805-21 | 2021 | | |
| Metabolism | SIMMER employs similarity algorithms to accurately identify human gut microbiome species and enzymes capable of known chemical transformations. | Bustion AE, Nayak RR, Agrawal A, Turnbaugh PJ, Pollard KS. | Elife | 10.7554/elife.82401 | 2023 | |
| The immunotoxicity, but not anti-tumor efficacy, of anti-CD40 and anti-CD137 immunotherapies is dependent on the gut microbiota. | Blake SJ, James J, Ryan FJ, Caparros-Martin J, Eden GL, Tee YC, Salamon JR, Benson SC, Tumes DJ, Sribnaia A, Stevens NE, Finnie JW, Kobayashi H, White DL, Wesselingh SL, O'Gara F, Lynn MA, Lynn DJ. | Cell Rep Med | 10.1016/j.xcrm.2021.100464 | 2021 | | |
| Assessment of Gram- and Viability-Staining Methods for Quantifying Bacterial Community Dynamics Using Flow Cytometry. | Duquenoy A, Bellais S, Gasc C, Schwintner C, Dore J, Thomas V. | Front Microbiol | 10.3389/fmicb.2020.01469 | 2020 | | |
| BaiCD gene cluster abundance is negatively correlated with Clostridium difficile infection. | Solbach P, Chhatwal P, Woltemate S, Tacconelli E, Buhl M, Gerhard M, Thoeringer CK, Vehreschild MJGT, Jazmati N, Rupp J, Manns MP, Bachmann O, Suerbaum S. | PLoS One | 10.1371/journal.pone.0196977 | 2018 | | |
| Metabolism | The gut bacterium Extibacter muris produces secondary bile acids and influences liver physiology in gnotobiotic mice. | Streidl T, Karkossa I, Segura Munoz RR, Eberl C, Zaufel A, Plagge J, Schmaltz R, Schubert K, Basic M, Schneider KM, Afify M, Trautwein C, Tolba R, Stecher B, Doden HL, Ridlon JM, Ecker J, Moustafa T, von Bergen M, Ramer-Tait AE, Clavel T. | Gut Microbes | 10.1080/19490976.2020.1854008 | 2021 | |
| Pathogenicity | The Use of Defined Microbial Communities To Model Host-Microbe Interactions in the Human Gut. | Elzinga J, van der Oost J, de Vos WM, Smidt H. | Microbiol Mol Biol Rev | 10.1128/mmbr.00054-18 | 2019 | |
| Metabolism | Methotrexate impacts conserved pathways in diverse human gut bacteria leading to decreased host immune activation. | Nayak RR, Alexander M, Deshpande I, Stapleton-Gray K, Rimal B, Patterson AD, Ubeda C, Scher JU, Turnbaugh PJ. | Cell Host Microbe | 10.1016/j.chom.2020.12.008 | 2021 | |
| Genetics | Pangenome Analysis of Clostridium scindens: A Collection of Diverse Bile Acid- and Steroid-Metabolizing Commensal Gut Bacterial Strains. | Olivos-Caicedo KY, Fernandez-Materan FV, Daniel SL, Anantharaman K, Ridlon JM, Alves JMP. | Microorganisms | 10.3390/microorganisms13040857 | 2025 | |
| Computer-Aided Molecular Modifications for Enhanced Activity and Thermal Stability of d-Allulose 3-Epimerase. | Guo T, Miao M, Zhang T. | J Agric Food Chem | 10.1021/acs.jafc.4c13007 | 2025 | | |
| Strain-dependent induction of primary bile acid 7-dehydroxylation by cholic acid. | Vico-Oton E, Volet C, Jacquemin N, Dong Y, Hapfelmeier S, Meibom KL, Bernier-Latmani R. | BMC Microbiol | 10.1186/s12866-024-03433-y | 2024 | | |
| BaiJ and BaiB are key enzymes in the chenodeoxycholic acid 7alpha-dehydroxylation pathway in the gut microbe Clostridium scindens ATCC 35704. | Meibom KL, Marion S, Volet C, Nass T, Vico-Oton E, Menin L, Bernier-Latmani R. | Gut Microbes | 10.1080/19490976.2024.2323233 | 2024 | | |
| Genome sequences of nine Clostridium scindens strains isolated from human feces. | Fernandez-Materan FV, Olivos-Caicedo KY, Daniel SL, Walden KKO, Fields CJ, Hernandez AG, Alves JMP, Ridlon JM. | Microbiol Resour Announc | 10.1128/mra.00848-24 | 2024 | | |
| Enzymology | Identification of gut bacteria reductases that biotransform steroid hormones. | Arp G, Jiang AK, Dufault-Thompson K, Levy S, Zhong A, Wassan JT, Grant MR, Li Y, Hall B, Jiang X. | Nat Commun | 10.1038/s41467-025-61425-6 | 2025 | |
| Potential relationship of the gut microbiome with testosterone level in men: a systematic review. | Pakpahan C, Laurus G, Hartanto MC, Singh R, Saharan A, Darmadi D, Rezano A, Wasian G. | PeerJ | 10.7717/peerj.19289 | 2025 | | |
| Bile acid 7alpha-dehydroxylating bacteria accelerate injury-induced mucosal healing in the colon. | Jalil A, Perino A, Dong Y, Imbach J, Volet C, Vico-Oton E, Demagny H, Plantade L, Gallart-Ayala H, Ivanisevic J, Bernier-Latmani R, Hapfelmeier S, Schoonjans K. | EMBO Mol Med | 10.1038/s44321-025-00202-w | 2025 | | |
| Clostridium scindens promotes gallstone formation by inducing intrahepatic neutrophil extracellular traps through CXCL1 produced by colonic epithelial cells. | Yao W, He Y, Xie Z, Wang Q, Chen Y, Yu J, Liu X, Xue DX, Liyi W, Hao C. | Microb Cell | 10.15698/mic2025.03.844 | 2025 | | |
| Intestinal microbiota composition and bile salt hydrolase activity in fast and slow growing broiler chickens: implications for growth performance and production efficiency. | Kim HW, Kim NK, Wolf PG, Brandvold K, Rehberger JM, Rehberger TG, Dilger RN, Smith AH, Mackie RI. | J Anim Sci Biotechnol | 10.1186/s40104-025-01243-4 | 2025 | | |
| Enzymology | In vitro characterization of alternative l-threonate and d-erythronate catabolic pathways. | Guo Y, Shen K, Zhang X, Huang H. | Biochem Biophys Res Commun | 10.1016/j.bbrc.2023.149440 | 2024 | |
| Production of deoxycholic acid by low-abundant microbial species is associated with impaired glucose metabolism. | Wahlstrom A, Brumbaugh A, Sjoland W, Olsson L, Wu H, Henricsson M, Lundqvist A, Makki K, Hazen SL, Bergstrom G, Marschall HU, Fischbach MA, Backhed F. | Nat Commun | 10.1038/s41467-024-48543-3 | 2024 | | |
| A high-dimensional platform for observing neutrophil-parasite interactions. | Thompson BA, Revilla J, Brovero S, Burgess SL. | Microbiol Spectr | 10.1128/spectrum.00472-24 | 2024 | | |
| Novel microbial modifications of bile acids and their functional implications. | Zheng D, Zhang H, Zheng X, Zhao A, Jia W. | Imeta | 10.1002/imt2.243 | 2024 | | |
| Metabolism | The Hylemon-Björkhem pathway of bile acid 7-dehydroxylation: history, biochemistry, and microbiology. | Ridlon JM, Daniel SL, Gaskins HR. | J Lipid Res | 10.1016/j.jlr.2023.100392 | 2023 | |
| In vitro co-culture of Clostridium scindens with primary human colonic epithelium protects the epithelium against Staphylococcus aureus. | Wang H, Kim R, Wang Y, Furtado KL, Sims CE, Tamayo R, Allbritton NL. | Front Bioeng Biotechnol | 10.3389/fbioe.2024.1382389 | 2024 | | |
| Bile acids impact the microbiota, host, and C. difficile dynamics providing insight into mechanisms of efficacy of FMTs and microbiota-focused therapeutics. | McMillan AS, Theriot CM. | Gut Microbes | 10.1080/19490976.2024.2393766 | 2024 | | |
| Metabolism | A small intestinal bile acid modulates the gut microbiome to improve host metabolic phenotypes following bariatric surgery. | Chen Y, Chaudhari SN, Harris DA, Roberts CF, Moscalu A, Mathur V, Zhao L, Tavakkoli A, Devlin AS, Sheu EG. | Cell Host Microbe | 10.1016/j.chom.2024.06.014 | 2024 | |
| Clostridium scindens exacerbates experimental necrotizing enterocolitis via upregulation of the apical sodium-dependent bile acid transporter. | Calton CM, Carothers K, Ramamurthy S, Jagadish N, Phanindra B, Garcia A, Viswanathan VK, Halpern MD. | Am J Physiol Gastrointest Liver Physiol | 10.1152/ajpgi.00102.2023 | 2024 | | |
| Metabolism | Strain dropouts reveal interactions that govern the metabolic output of the gut microbiome. | Wang M, Osborn LJ, Jain S, Meng X, Weakley A, Yan J, Massey WJ, Varadharajan V, Horak A, Banerjee R, Allende DS, Chan ER, Hajjar AM, Wang Z, Dimas A, Zhao A, Nagashima K, Cheng AG, Higginbottom S, Hazen SL, Brown JM, Fischbach MA. | Cell | 10.1016/j.cell.2023.05.037 | 2023 | |
| Metabolism | Bacterial steroid-17,20-desmolase is a taxonomically rare enzymatic pathway that converts prednisone to 1,4-androstanediene-3,11,17-trione, a metabolite that causes proliferation of prostate cancer cells. | Ly LK, Rowles JL, Paul HM, Alves JMP, Yemm C, Wolf PM, Devendran S, Hudson ME, Morris DJ, Erdman JW, Ridlon JM. | J Steroid Biochem Mol Biol | 10.1016/j.jsbmb.2019.105567 | 2020 | |
| Enzymology | Microbial Hydroxysteroid Dehydrogenases: From Alpha to Omega. | Doden HL, Ridlon JM. | Microorganisms | 10.3390/microorganisms9030469 | 2021 | |
| Metabolism | Conceptualizing the Vertebrate Sterolbiome. | Ridlon JM. | Appl Environ Microbiol | 10.1128/aem.00641-20 | 2020 | |
| Metabolism | Novel Approaches in Glucose and Lipid Metabolism Disorder Therapy: Targeting the Gut Microbiota-Bile Acid Axis. | Jiang J, Zhang H, Hussain M, Abdullah, Feng F, Guan R, Zhong H. | Biology (Basel) | 10.3390/biology14070802 | 2025 | |
| Metabolism | Bile Acid 7alpha-Dehydroxylating Gut Bacteria Secrete Antibiotics that Inhibit Clostridium difficile: Role of Secondary Bile Acids. | Kang JD, Myers CJ, Harris SC, Kakiyama G, Lee IK, Yun BS, Matsuzaki K, Furukawa M, Min HK, Bajaj JS, Zhou H, Hylemon PB. | Cell Chem Biol | 10.1016/j.chembiol.2018.10.003 | 2019 | |
| Enzymology | Formation of secondary allo-bile acids by novel enzymes from gut Firmicutes. | Lee JW, Cowley ES, Wolf PG, Doden HL, Murai T, Caicedo KYO, Ly LK, Sun F, Takei H, Nittono H, Daniel SL, Cann I, Gaskins HR, Anantharaman K, Alves JMP, Ridlon JM. | Gut Microbes | 10.1080/19490976.2022.2132903 | 2022 | |
| Metabolism | The 7-alpha-dehydroxylation pathway: An integral component of gut bacterial bile acid metabolism and potential therapeutic target. | Wise JL, Cummings BP. | Front Microbiol | 10.3389/fmicb.2022.1093420 | 2022 | |
| Phylogeny | Hybrid sequence-based analysis reveals the distribution of bacterial species and genes in the oral microbiome at a high resolution. | Yamaguchi M, Uchihashi T, Kawabata S. | Biochem Biophys Rep | 10.1016/j.bbrep.2024.101717 | 2024 | |
| Metabolism | Gut feelings about bacterial steroid-17,20-desmolase. | Ly LK, Doden HL, Ridlon JM. | Mol Cell Endocrinol | 10.1016/j.mce.2021.111174 | 2021 | |
| Metabolic immaturity and breastmilk bile acid metabolites are central determinants of heightened newborn vulnerability to norovirus diarrhea. | Peiper AM, Morales Aparicio J, Hu Z, Phophi L, Helm EW, Rubinstein RJ, Phillips M, Williams CG, Subramanian S, Cross M, Iyer N, Nguyen Q, Newsome R, Jobin C, Langel SN, Bucardo F, Becker-Dreps S, Tan XD, Dawson PA, Karst SM. | Cell Host Microbe | 10.1016/j.chom.2024.08.003 | 2024 | | |
| Metabolism | Biogeography of microbial bile acid transformations along the murine gut. | Marion S, Desharnais L, Studer N, Dong Y, Notter MD, Poudel S, Menin L, Janowczyk A, Hettich RL, Hapfelmeier S, Bernier-Latmani R. | J Lipid Res | 10.1194/jlr.ra120001021 | 2020 | |
| Gut microbiome communication with bone marrow regulates susceptibility to amebiasis. | Burgess SL, Leslie JL, Uddin J, Oakland DN, Gilchrist C, Moreau GB, Watanabe K, Saleh M, Simpson M, Thompson BA, Auble DT, Turner SD, Giallourou N, Swann J, Pu Z, Ma JZ, Haque R, Petri WA. | J Clin Invest | 10.1172/jci133605 | 2020 | | |
| Metabolism | In vitro and in vivo characterization of Clostridium scindens bile acid transformations. | Marion S, Studer N, Desharnais L, Menin L, Escrig S, Meibom A, Hapfelmeier S, Bernier-Latmani R. | Gut Microbes | 10.1080/19490976.2018.1549420 | 2019 | |
| Metabolism | Metabolism of Oxo-Bile Acids and Characterization of Recombinant 12alpha-Hydroxysteroid Dehydrogenases from Bile Acid 7alpha-Dehydroxylating Human Gut Bacteria. | Doden H, Sallam LA, Devendran S, Ly L, Doden G, Daniel SL, Alves JMP, Ridlon JM. | Appl Environ Microbiol | 10.1128/aem.00235-18 | 2018 | |
| Metabolism | Do Primocolonizing Bacteria Enable Bacteroides thetaiotaomicron Intestinal Colonization Independently of the Capacity To Consume Oxygen? | Halpern D, Morvan C, Derre-Bobillot A, Meylheuc T, Guillemet M, Rabot S, Gruss A. | mSphere | 10.1128/msphere.00232-19 | 2021 | |
| Metabolism | Completion of the gut microbial epi-bile acid pathway. | Doden HL, Wolf PG, Gaskins HR, Anantharaman K, Alves JMP, Ridlon JM. | Gut Microbes | 10.1080/19490976.2021.1907271 | 2021 | |
| Genetics | Discovery of antimicrobial peptides in the global microbiome with machine learning. | Santos-Junior CD, Torres MDT, Duan Y, Rodriguez Del Rio A, Schmidt TSB, Chong H, Fullam A, Kuhn M, Zhu C, Houseman A, Somborski J, Vines A, Zhao XM, Bork P, Huerta-Cepas J, de la Fuente-Nunez C, Coelho LP. | Cell | 10.1016/j.cell.2024.05.013 | 2024 | |
| Identification and Characterization of Major Bile Acid 7alpha-Dehydroxylating Bacteria in the Human Gut. | Kim KH, Park D, Jia B, Baek JH, Hahn Y, Jeon CO. | mSystems | 10.1128/msystems.00455-22 | 2022 | | |
| Contribution of Inhibitory Metabolites and Competition for Nutrients to Colonization Resistance against Clostridioides difficile by Commensal Clostridium. | Reed AD, Theriot CM. | Microorganisms | 10.3390/microorganisms9020371 | 2021 | | |
| Secondary bile acids mediate high-fat diet-induced upregulation of R-spondin 3 and intestinal epithelial proliferation. | Li JY, Gillilland M, Lee AA, Wu X, Zhou SY, Owyang C. | JCI Insight | 10.1172/jci.insight.148309 | 2022 | | |
| Enzymology | Identification and characterization of a 20beta-HSDH from the anaerobic gut bacterium Butyricicoccus desmolans ATCC 43058. | Devendran S, Mendez-Garcia C, Ridlon JM. | J Lipid Res | 10.1194/jlr.m074914 | 2017 | |
| Biological tuners to reshape the bile acid pool for therapeutic purposes in non-alcoholic fatty liver disease. | Gillard J, Leclercq IA. | Clin Sci (Lond) | 10.1042/cs20220697 | 2023 | | |
| Metabolism | Structural and biochemical characterization of 20beta-hydroxysteroid dehydrogenase from Bifidobacterium adolescentis strain L2-32. | Doden HL, Pollet RM, Mythen SM, Wawrzak Z, Devendran S, Cann I, Koropatkin NM, Ridlon JM. | J Biol Chem | 10.1074/jbc.ra119.009390 | 2019 | |
| Enriched pathways in gut microbiome predict response to immune checkpoint inhibitor treatment across demographic regions and various cancer types. | Cai X, Cho JY, Chen L, Liu Y, Ji F, Salgado K, Ge S, Yang D, Yu H, Shao J, Futreal PA, Sepesi B, Gibbons D, Chen Y, Wang G, Cheng C, Wu M, Zhang J, Hsiao A, Xia T. | iScience | 10.1016/j.isci.2025.112162 | 2025 | | |
| Recent Advances Regarding the Physiological Functions and Biosynthesis of D-Allulose. | Chen Z, Gao XD, Li Z. | Front Microbiol | 10.3389/fmicb.2022.881037 | 2022 | | |
| Metabolism | Clostridium scindens: a human gut microbe with a high potential to convert glucocorticoids into androgens. | Ridlon JM, Ikegawa S, Alves JM, Zhou B, Kobayashi A, Iida T, Mitamura K, Tanabe G, Serrano M, De Guzman A, Cooper P, Buck GA, Hylemon PB. | J Lipid Res | 10.1194/jlr.m038869 | 2013 | |
| Metabolism | Consequences of bile salt biotransformations by intestinal bacteria. | Ridlon JM, Harris SC, Bhowmik S, Kang DJ, Hylemon PB. | Gut Microbes | 10.1080/19490976.2015.1127483 | 2016 | |
| Metabolism | A dysregulated bile acid-gut microbiota axis contributes to obesity susceptibility. | Wei M, Huang F, Zhao L, Zhang Y, Yang W, Wang S, Li M, Han X, Ge K, Qu C, Rajani C, Xie G, Zheng X, Zhao A, Bian Z, Jia W. | EBioMedicine | 10.1016/j.ebiom.2020.102766 | 2020 | |
| Metabolism | Mapping human microbiome drug metabolism by gut bacteria and their genes. | Zimmermann M, Zimmermann-Kogadeeva M, Wegmann R, Goodman AL. | Nature | 10.1038/s41586-019-1291-3 | 2019 | |
| Enzymology | Identification and characterization of two bile acid coenzyme A transferases from Clostridium scindens, a bile acid 7alpha-dehydroxylating intestinal bacterium. | Ridlon JM, Hylemon PB. | J Lipid Res | 10.1194/jlr.m020313 | 2012 | |
| Metabolism | Elevated serum ceramides are linked with obesity-associated gut dysbiosis and impaired glucose metabolism. | Kayser BD, Prifti E, Lhomme M, Belda E, Dao MC, Aron-Wisnewsky J, MICRO-Obes Consortium, Kontush A, Zucker JD, Rizkalla SW, Dugail I, Clement K. | Metabolomics | 10.1007/s11306-019-1596-0 | 2019 | |
| Pathogenicity | A microbiota-generated bile salt induces biofilm formation in Clostridium difficile. | Dubois T, Tremblay YDN, Hamiot A, Martin-Verstraete I, Deschamps J, Monot M, Briandet R, Dupuy B. | NPJ Biofilms Microbiomes | 10.1038/s41522-019-0087-4 | 2019 | |
| TREM2 deficiency reprograms intestinal macrophages and microbiota to enhance anti-PD-1 tumor immunotherapy. | Di Luccia B, Molgora M, Khantakova D, Jaeger N, Chang HW, Czepielewski RS, Helmink BA, Onufer EJ, Fachi JL, Bhattarai B, Trsan T, Rodrigues PF, Hou J, Bando JK, da Silva CS, Cella M, Gilfillan S, Schreiber RD, Gordon JI, Colonna M. | Sci Immunol | 10.1126/sciimmunol.adi5374 | 2024 | | |
| Pathogenicity | Microbiota-derived bile acids antagonize the host androgen receptor and drive anti-tumor immunity. | Jin WB, Xiao L, Jeong M, Han SJ, Zhang W, Yano H, Shi H, Arifuzzaman M, Lyu M, Wang D, Tang YA, Qiao S, JRI IBD Live Cell Bank Consortium, Yang X, Yang HS, Fu J, Sonnenberg GF, Collins N, Artis D, Guo CJ. | Cell | 10.1016/j.cell.2025.02.029 | 2025 | |
| Potential role of gut microbiota in prostate cancer: immunity, metabolites, pathways of action? | Zha C, Peng Z, Huang K, Tang K, Wang Q, Zhu L, Che B, Li W, Xu S, Huang T, Yu Y, Zhang W. | Front Oncol | 10.3389/fonc.2023.1196217 | 2023 | | |
| Microbiome-encoded bile acid metabolism modulates colonic transit times. | Li N, Koester ST, Lachance DM, Dutta M, Cui JY, Dey N. | iScience | 10.1016/j.isci.2021.102508 | 2021 | | |
| The Stickland Reaction Precursor trans-4-Hydroxy-l-Proline Differentially Impacts the Metabolism of Clostridioides difficile and Commensal Clostridia. | Reed AD, Fletcher JR, Huang YY, Thanissery R, Rivera AJ, Parsons RJ, Stewart AK, Kountz DJ, Shen A, Balskus EP, Theriot CM. | mSphere | 10.1128/msphere.00926-21 | 2022 | | |
| Enzymology | Structure and functional characterization of a bile acid 7alpha dehydratase BaiE in secondary bile acid synthesis. | Bhowmik S, Chiu HP, Jones DH, Chiu HJ, Miller MD, Xu Q, Farr CL, Ridlon JM, Wells JE, Elsliger MA, Wilson IA, Hylemon PB, Lesley SA. | Proteins | 10.1002/prot.24971 | 2016 | |
| Gut Microbiota Ecosystem Governance of Host Inflammation, Mitochondrial Respiration and Skeletal Homeostasis. | Lian WS, Wang FS, Chen YS, Tsai MH, Chao HR, Jahr H, Wu RW, Ko JY. | Biomedicines | 10.3390/biomedicines10040860 | 2022 | | |
| Gut microbiome influences incidence and outcomes of breast cancer by regulating levels and activity of steroid hormones in women. | Chapadgaonkar SS, Bajpai SS, Godbole MS. | Cancer Rep (Hoboken) | 10.1002/cnr2.1847 | 2023 | | |
| Biotechnology | Applications of Bacillus subtilis Spores in Biotechnology and Advanced Materials. | Zhang X, Al-Dossary A, Hussain M, Setlow P, Li J. | Appl Environ Microbiol | 10.1128/aem.01096-20 | 2020 | |
| Metabolism | Western diet induces Paneth cell defects through microbiome alterations and farnesoid X receptor and type I interferon activation. | Liu TC, Kern JT, Jain U, Sonnek NM, Xiong S, Simpson KF, VanDussen KL, Winkler ES, Haritunians T, Malique A, Lu Q, Sasaki Y, Storer C, Diamond MS, Head RD, McGovern DPB, Stappenbeck TS. | Cell Host Microbe | 10.1016/j.chom.2021.04.004 | 2021 | |
| Endocrinology of the Aging Prostate: Current Concepts. | Cannarella R, Condorelli RA, Barbagallo F, La Vignera S, Calogero AE. | Front Endocrinol (Lausanne) | 10.3389/fendo.2021.554078 | 2021 | | |
| A dysbiotic gut microbiome suppresses antibody mediated-protection against Vibrio cholerae. | Macbeth JC, Liu R, Alavi S, Hsiao A. | iScience | 10.1016/j.isci.2021.103443 | 2021 | | |
| Clostridium sporogenes uses reductive Stickland metabolism in the gut to generate ATP and produce circulating metabolites. | Liu Y, Chen H, Van Treuren W, Hou BH, Higginbottom SK, Dodd D. | Nat Microbiol | 10.1038/s41564-022-01109-9 | 2022 | | |
| A Small Molecule-Screening Pipeline to Evaluate the Therapeutic Potential of 2-Aminoimidazole Molecules Against Clostridium difficile. | Thanissery R, Zeng D, Doyle RG, Theriot CM. | Front Microbiol | 10.3389/fmicb.2018.01206 | 2018 | | |
| Deep-learning-enabled antibiotic discovery through molecular de-extinction. | Wan F, Torres MDT, Peng J, de la Fuente-Nunez C. | Nat Biomed Eng | 10.1038/s41551-024-01201-x | 2024 | | |
| Genetics | Uneven distribution of cobamide biosynthesis and dependence in bacteria predicted by comparative genomics. | Shelton AN, Seth EC, Mok KC, Han AW, Jackson SN, Haft DR, Taga ME. | ISME J | 10.1038/s41396-018-0304-9 | 2019 | |
| Influence of four retail food service cooling methods on the behavior of Clostridium perfringens ATCC 10388 in turkey roasts following heating to an internal temperature of 74 degrees C. | Olds DA, Mendonca AF, Sneed J, Bisha B. | J Food Prot | 10.4315/0362-028x-69.1.112 | 2006 | | |
| Pathogenicity | A Gut-Restricted Lithocholic Acid Analog as an Inhibitor of Gut Bacterial Bile Salt Hydrolases. | Adhikari AA, Ramachandran D, Chaudhari SN, Powell CE, Li W, McCurry MD, Banks AS, Devlin AS. | ACS Chem Biol | 10.1021/acschembio.1c00192 | 2021 | |
| Metabolism | A Clostridia-rich microbiota enhances bile acid excretion in diarrhea-predominant irritable bowel syndrome. | Zhao L, Yang W, Chen Y, Huang F, Lu L, Lin C, Huang T, Ning Z, Zhai L, Zhong LL, Lam W, Yang Z, Zhang X, Cheng C, Han L, Qiu Q, Shang X, Huang R, Xiao H, Ren Z, Chen D, Sun S, El-Nezami H, Cai Z, Lu A, Fang X, Jia W, Bian Z. | J Clin Invest | 10.1172/jci130976 | 2020 | |
| Metabolism | Bacterial riboswitches cooperatively bind Ni(2+) or Co(2+) ions and control expression of heavy metal transporters. | Furukawa K, Ramesh A, Zhou Z, Weinberg Z, Vallery T, Winkler WC, Breaker RR. | Mol Cell | 10.1016/j.molcel.2015.02.009 | 2015 | |
| Design, construction, and in vivo augmentation of a complex gut microbiome. | Cheng AG, Ho PY, Aranda-Diaz A, Jain S, Yu FB, Meng X, Wang M, Iakiviak M, Nagashima K, Zhao A, Murugkar P, Patil A, Atabakhsh K, Weakley A, Yan J, Brumbaugh AR, Higginbottom S, Dimas A, Shiver AL, Deutschbauer A, Neff N, Sonnenburg JL, Huang KC, Fischbach MA. | Cell | 10.1016/j.cell.2022.08.003 | 2022 | | |
| Review on D-Allulose: In vivo Metabolism, Catalytic Mechanism, Engineering Strain Construction, Bio-Production Technology. | Jiang S, Xiao W, Zhu X, Yang P, Zheng Z, Lu S, Jiang S, Zhang G, Liu J. | Front Bioeng Biotechnol | 10.3389/fbioe.2020.00026 | 2020 | | |
| Characterization of tet(32) genes from the oral metagenome. | Warburton P, Roberts AP, Allan E, Seville L, Lancaster H, Mullany P. | Antimicrob Agents Chemother | 10.1128/aac.00788-08 | 2009 | | |
| Metabolism | Diet-induced remission in chronic enteropathy is associated with altered microbial community structure and synthesis of secondary bile acids. | Wang S, Martins R, Sullivan MC, Friedman ES, Misic AM, El-Fahmawi A, De Martinis ECP, O'Brien K, Chen Y, Bradley C, Zhang G, Berry ASF, Hunter CA, Baldassano RN, Rondeau MP, Beiting DP. | Microbiome | 10.1186/s40168-019-0740-4 | 2019 | |
| GapMind: Automated Annotation of Amino Acid Biosynthesis. | Price MN, Deutschbauer AM, Arkin AP. | mSystems | 10.1128/msystems.00291-20 | 2020 | | |
| The Metadata Coverage Index (MCI): A standardized metric for quantifying database metadata richness. | Liolios K, Schriml L, Hirschman L, Pagani I, Nosrat B, Sterk P, White O, Rocca-Serra P, Sansone SA, Taylor C, Kyrpides NC, Field D. | Stand Genomic Sci | 10.4056/sigs.2675953 | 2012 | | |
| Comparative Analysis of two Component Signal Transduction Systems of the Lactobacillus Acidophilus Group. | Cui Y, Qu X. | Braz J Microbiol | 10.1590/s1517-83822011000100019 | 2011 | | |
| Metabolism | Indoleacrylic Acid Produced by Commensal Peptostreptococcus Species Suppresses Inflammation. | Wlodarska M, Luo C, Kolde R, d'Hennezel E, Annand JW, Heim CE, Krastel P, Schmitt EK, Omar AS, Creasey EA, Garner AL, Mohammadi S, O'Connell DJ, Abubucker S, Arthur TD, Franzosa EA, Huttenhower C, Murphy LO, Haiser HJ, Vlamakis H, Porter JA, Xavier RJ. | Cell Host Microbe | 10.1016/j.chom.2017.06.007 | 2017 | |
| Metabolism | A metabolomic and pharmacokinetic study on the mechanism underlying the lipid-lowering effect of orally administered berberine. | Gu S, Cao B, Sun R, Tang Y, Paletta JL, Wu X, Liu L, Zha W, Zhao C, Li Y, Ridlon JM, Hylemon PB, Zhou H, Aa J, Wang G. | Mol Biosyst | 10.1039/c4mb00500g | 2015 | |
| Metabolism | Bacterial metabolism of bile acids promotes generation of peripheral regulatory T cells. | Campbell C, McKenney PT, Konstantinovsky D, Isaeva OI, Schizas M, Verter J, Mai C, Jin WB, Guo CJ, Violante S, Ramos RJ, Cross JR, Kadaveru K, Hambor J, Rudensky AY. | Nature | 10.1038/s41586-020-2193-0 | 2020 | |
| Phylogeny | A collection of bacterial isolates from the pig intestine reveals functional and taxonomic diversity. | Wylensek D, Hitch TCA, Riedel T, Afrizal A, Kumar N, Wortmann E, Liu T, Devendran S, Lesker TR, Hernandez SB, Heine V, Buhl EM, M D'Agostino P, Cumbo F, Fischoder T, Wyschkon M, Looft T, Parreira VR, Abt B, Doden HL, Ly L, Alves JMP, Reichlin M, Flisikowski K, Suarez LN, Neumann AP, Suen G, de Wouters T, Rohn S, Lagkouvardos I, Allen-Vercoe E, Sproer C, Bunk B, Taverne-Thiele AJ, Giesbers M, Wells JM, Neuhaus K, Schnieke A, Cava F, Segata N, Elling L, Strowig T, Ridlon JM, Gulder TAM, Overmann J, Clavel T. | Nat Commun | 10.1038/s41467-020-19929-w | 2020 | |
| Transcriptome | Transcriptome Sequencing of Listeria monocytogenes Reveals Major Gene Expression Changes in Response to Lactic Acid Stress Exposure but a Less Pronounced Response to Oxidative Stress. | Cortes BW, Naditz AL, Anast JM, Schmitz-Esser S. | Front Microbiol | 10.3389/fmicb.2019.03110 | 2019 | |
| Food Additive P-80 Impacts Mouse Gut Microbiota Promoting Intestinal Inflammation, Obesity and Liver Dysfunction. | Singh RK, Wheildon N, Ishikawa S. | SOJ Microbiol Infect Dis | 10.15226/sojmid/4/1/00148 | 2016 | | |
| Genetics | FSL J1-208, a virulent uncommon phylogenetic lineage IV Listeria monocytogenes strain with a small chromosome size and a putative virulence plasmid carrying internalin-like genes. | den Bakker HC, Bowen BM, Rodriguez-Rivera LD, Wiedmann M. | Appl Environ Microbiol | 10.1128/aem.06969-11 | 2012 | |
| Metabolism | Blood group antigen recognition by a solute-binding protein from a serotype 3 strain of Streptococcus pneumoniae. | Higgins MA, Abbott DW, Boulanger MJ, Boraston AB. | J Mol Biol | 10.1016/j.jmb.2009.03.012 | 2009 | |
| Metabolism | Products of gut microbial Toll/interleukin-1 receptor domain NADase activities in gnotobiotic mice and Bangladeshi children with malnutrition. | Weagley JS, Zaydman M, Venkatesh S, Sasaki Y, Damaraju N, Yenkin A, Buchser W, Rodionov DA, Osterman A, Ahmed T, Barratt MJ, DiAntonio A, Milbrandt J, Gordon JI. | Cell Rep | 10.1016/j.celrep.2022.110738 | 2022 | |
| Metabolism | A gut bacterial pathway metabolizes aromatic amino acids into nine circulating metabolites. | Dodd D, Spitzer MH, Van Treuren W, Merrill BD, Hryckowian AJ, Higginbottom SK, Le A, Cowan TM, Nolan GP, Fischbach MA, Sonnenburg JL. | Nature | 10.1038/nature24661 | 2017 | |
| Metabolism | Biological systems discovery in silico: radical S-adenosylmethionine protein families and their target peptides for posttranslational modification. | Haft DH, Basu MK. | J Bacteriol | 10.1128/jb.00040-11 | 2011 | |
| Metabolism | The minor pilin subunit Sgp2 is necessary for assembly of the pilus encoded by the srtG cluster of Streptococcus suis. | Okura M, Osaki M, Fittipaldi N, Gottschalk M, Sekizaki T, Takamatsu D. | J Bacteriol | 10.1128/jb.01555-09 | 2011 | |
| Metabolism | Assessment of fecal bacteria with bile acid 7 alpha-dehydroxylating activity for the presence of bai-like genes. | Doerner KC, Takamine F, LaVoie CP, Mallonee DH, Hylemon PB. | Appl Environ Microbiol | 10.1128/aem.63.3.1185-1188.1997 | 1997 | |
| Metabolism | Gut microbiome-mediated bile acid metabolism regulates liver cancer via NKT cells. | Ma C, Han M, Heinrich B, Fu Q, Zhang Q, Sandhu M, Agdashian D, Terabe M, Berzofsky JA, Fako V, Ritz T, Longerich T, Theriot CM, McCulloch JA, Roy S, Yuan W, Thovarai V, Sen SK, Ruchirawat M, Korangy F, Wang XW, Trinchieri G, Greten TF. | Science | 10.1126/science.aan5931 | 2018 | |
| Metabolism | Systematic assessment of secondary bile acid metabolism in gut microbes reveals distinct metabolic capabilities in inflammatory bowel disease. | Heinken A, Ravcheev DA, Baldini F, Heirendt L, Fleming RMT, Thiele I. | Microbiome | 10.1186/s40168-019-0689-3 | 2019 | |
| Pathogenicity | Enhancement of biocontrol efficacy of Pichia carribbica to postharvest diseases of strawberries by addition of trehalose to the growth medium. | Zhao L, Zhang H, Li J, Cui J, Zhang X, Ren X. | Int J Mol Sci | 10.3390/ijms13033916 | 2012 | |
| Metabolism | Alternative spermidine biosynthetic route is critical for growth of Campylobacter jejuni and is the dominant polyamine pathway in human gut microbiota. | Hanfrey CC, Pearson BM, Hazeldine S, Lee J, Gaskin DJ, Woster PM, Phillips MA, Michael AJ. | J Biol Chem | 10.1074/jbc.m111.307835 | 2011 | |
| Analysis of the mobilization functions of the vancomycin resistance transposon Tn1549, a member of a new family of conjugative elements. | Tsvetkova K, Marvaud JC, Lambert T. | J Bacteriol | 10.1128/jb.00680-09 | 2010 | | |
| Enzymology | Identification of a novel two-peptide lantibiotic, lichenicidin, following rational genome mining for LanM proteins. | Begley M, Cotter PD, Hill C, Ross RP. | Appl Environ Microbiol | 10.1128/aem.00730-09 | 2009 | |
| Metabolism | The Stringent Response Determines the Ability of a Commensal Bacterium to Survive Starvation and to Persist in the Gut. | Schofield WB, Zimmermann-Kogadeeva M, Zimmermann M, Barry NA, Goodman AL. | Cell Host Microbe | 10.1016/j.chom.2018.06.002 | 2018 | |
| Spatial organization of a model 15-member human gut microbiota established in gnotobiotic mice. | Mark Welch JL, Hasegawa Y, McNulty NP, Gordon JI, Borisy GG. | Proc Natl Acad Sci U S A | 10.1073/pnas.1711596114 | 2017 | | |
| Pathogenicity | Personalized Mapping of Drug Metabolism by the Human Gut Microbiome. | Javdan B, Lopez JG, Chankhamjon P, Lee YJ, Hull R, Wu Q, Wang X, Chatterjee S, Donia MS. | Cell | 10.1016/j.cell.2020.05.001 | 2020 | |
| Enzymology | Purification and characterization of a novel form of 20 alpha-hydroxysteroid dehydrogenase from Clostridium scindens. | Krafft AE, Hylemon PB. | J Bacteriol | 10.1128/jb.171.6.2925-2932.1989 | 1989 | |
| Proteomic indicators of oxidation and hydration state in colorectal cancer. | Dick JM. | PeerJ | 10.7717/peerj.2238 | 2016 | | |
| Microbial co-habitation and lateral gene transfer: what transposases can tell us. | Hooper SD, Mavromatis K, Kyrpides NC. | Genome Biol | 10.1186/gb-2009-10-4-r45 | 2009 | | |
| The RepA_N replicons of Gram-positive bacteria: a family of broadly distributed but narrow host range plasmids. | Weaver KE, Kwong SM, Firth N, Francia MV. | Plasmid | 10.1016/j.plasmid.2008.11.004 | 2009 | | |
| Noncellulosomal cohesin- and dockerin-like modules in the three domains of life. | Peer A, Smith SP, Bayer EA, Lamed R, Borovok I. | FEMS Microbiol Lett | 10.1111/j.1574-6968.2008.01420.x | 2009 | | |
| Paired microbiome and metabolome analyses associate bile acid changes with colorectal cancer progression. | Fu T, Huan T, Rahman G, Zhi H, Xu Z, Oh TG, Guo J, Coulter S, Tripathi A, Martino C, McCarville JL, Zhu Q, Cayabyab F, Low B, He M, Xing S, Vargas F, Yu RT, Atkins A, Liddle C, Ayres J, Raffatellu M, Dorrestein PC, Downes M, Knight R, Evans RM. | Cell Rep | 10.1016/j.celrep.2023.112997 | 2023 | | |
| Bacterial Lipopolysaccharide Destabilizes Influenza Viruses. | Bandoro C, Runstadler JA. | mSphere | 10.1128/msphere.00267-17 | 2017 | | |
| Metabolism | Strain-Dependent Inhibition of Clostridioides difficile by Commensal Clostridia Carrying the Bile Acid-Inducible (bai) Operon. | Reed AD, Nethery MA, Stewart A, Barrangou R, Theriot CM | J Bacteriol | 10.1128/JB.00039-20 | 2020 | |
| Metabolism | Clostridium scindens ATCC 35704: Integration of Nutritional Requirements, the Complete Genome Sequence, and Global Transcriptional Responses to Bile Acids. | Devendran S, Shrestha R, Alves JMP, Wolf PG, Ly L, Hernandez AG, Mendez-Garcia C, Inboden A, Wiley J, Paul O, Allen A, Springer E, Wright CL, Fields CJ, Daniel SL, Ridlon JM | Appl Environ Microbiol | 10.1128/AEM.00052-19 | 2019 | |
| Enzymology | The desA and desB genes from Clostridium scindens ATCC 35704 encode steroid-17,20-desmolase. | Devendran S, Mythen SM, Ridlon JM | J Lipid Res | 10.1194/jlr.M083949 | 2018 | |
| Metabolism | Identification of a gene encoding a flavoprotein involved in bile acid metabolism by the human gut bacterium Clostridium scindens ATCC 35704. | Harris SC, Devendran S, Alves JMP, Mythen SM, Hylemon PB, Ridlon JM | Biochim Biophys Acta Mol Cell Biol Lipids | 10.1016/j.bbalip.2017.12.001 | 2017 | |
| Metabolism | Production of d-Allulose with d-Psicose 3-Epimerase Expressed and Displayed on the Surface of Bacillus subtilis Spores. | He W, Jiang B, Mu W, Zhang T | J Agric Food Chem | 10.1021/acs.jafc.6b03347 | 2016 | |
| Enzymology | Characterization of a novel metal-dependent D-psicose 3-epimerase from Clostridium scindens 35704. | Zhang W, Fang D, Xing Q, Zhou L, Jiang B, Mu W | PLoS One | 10.1371/journal.pone.0062987 | 2013 | |
| Genetics | Luxibacter massiliensis gen. nov., sp. nov., a new bacterium isolated from the human gut microbiota. | Naud S, Bellali S, Anani H, Lo CI, Yacouba A, Tidjani Alou M, Armstrong N, Bonvalet M, Zitvogel L, Raoult D, Lagier JC. | New Microbes New Infect | 10.1016/j.nmni.2021.100850 | 2021 | |
| Phylogeny | Sporofaciens musculi gen. nov., sp. nov., a novel bacterium isolated from the caecum of an obese mouse. | Rasmussen TS, Streidl T, Hitch TCA, Wortmann E, Deptula P, Kofoed MVW, Riedel T, Neumann-Schaal M, Hansen M, Nielsen DS, Clavel T, Vogensen FK | Int J Syst Evol Microbiol | 10.1099/ijsem.0.004673 | 2021 | |
| Phylogeny | Assignment of Eubacterium sp. VPI 12708 and related strains with high bile acid 7alpha-dehydroxylating activity to Clostridium scindens and proposal of Clostridium hylemonae sp. nov., isolated from human faeces. | Kitahara M, Takamine F, Imamura T, Benno Y | Int J Syst Evol Microbiol | 10.1099/00207713-50-3-971 | 2000 | |
How to citeIf you want to cite this particular strain cite the following doi:
https://doi.org/10.13145/bacdive2748.20251217.10
When using BacDive for research please cite the following paper
BacDive in 2025: the core database for prokaryotic strain data
License