Clostridium ramosum 113-I is an anaerobe bacterium of the family Clostridiaceae.
anaerobe genome sequence 16S sequence Bacteria| @ref 20215 |
|
|
| Domain Bacteria |
| Phylum Bacillota |
| Class Clostridia |
| Order Eubacteriales |
| Family Clostridiaceae |
| Genus Clostridium |
| Species Clostridium ramosum |
| Full scientific name Clostridium ramosum (Veillon and Zuber 1898) Holdeman et al. 1971 (Approved Lists 1980) |
| Synonyms (3) |
| BacDive ID | Other strains from Clostridium ramosum (8) | Type strain |
|---|---|---|
| 148490 | C. ramosum CCUG 35540 | |
| 148608 | C. ramosum CCUG 35705 | |
| 150967 | C. ramosum CCUG 42893 | |
| 151816 | C. ramosum CCUG 44972 | |
| 151840 | C. ramosum CCUG 45030 | |
| 152520 | C. ramosum CCUG 46995 | |
| 154479 | C. ramosum CCUG 53777 | |
| 165123 | C. ramosum JCM 5235, ATCC 13937, NCTC 10474 |
| @ref | Name | Growth | Medium link | Composition | |
|---|---|---|---|---|---|
| 489 | COLUMBIA BLOOD MEDIUM (DSMZ Medium 693) | Medium recipe at MediaDive | Name: COLUMBIA BLOOD MEDIUM (DSMZ Medium 693) Composition: Defibrinated sheep blood 50.0 g/l Columbia agar base | ||
| 489 | FASTIDIOUS ANAEROBE BROTH (DSMZ Medium 1203a) | Medium recipe at MediaDive | Name: FASTIDIOUS ANAEROBE BROTH (DSMZ Medium 1203a) Composition: Fastidious Anaerobe Basal Broth 35.4 g/l Deionized water |
| @ref | Chebi-ID | Metabolite | Utilization activity | Kind of utilization tested | |
|---|---|---|---|---|---|
| 68367 | 17057 ChEBI | cellobiose | + | builds acid from | from API 20A |
| 68367 | 17634 ChEBI | D-glucose | + | builds acid from | from API 20A |
| 68367 | 16899 ChEBI | D-mannitol | + | builds acid from | from API 20A |
| 68367 | 16024 ChEBI | D-mannose | + | builds acid from | from API 20A |
| 68367 | 65327 ChEBI | D-xylose | - | builds acid from | from API 20A |
| 68367 | 4853 ChEBI | esculin | + | hydrolysis | from API 20A |
| 68367 | 5291 ChEBI | gelatin | - | hydrolysis | from API 20A |
| 68367 | 17754 ChEBI | glycerol | - | builds acid from | from API 20A |
| 68367 | 30849 ChEBI | L-arabinose | - | builds acid from | from API 20A |
| 68367 | 62345 ChEBI | L-rhamnose | - | builds acid from | from API 20A |
| 68367 | 17716 ChEBI | lactose | + | builds acid from | from API 20A |
| 68367 | 17306 ChEBI | maltose | + | builds acid from | from API 20A |
| 68367 | 6731 ChEBI | melezitose | - | builds acid from | from API 20A |
| 68367 | 16634 ChEBI | raffinose | + | builds acid from | from API 20A |
| 68367 | 17814 ChEBI | salicin | + | builds acid from | from API 20A |
| 68367 | 30911 ChEBI | sorbitol | - | builds acid from | from API 20A |
| 68367 | 17992 ChEBI | sucrose | + | builds acid from | from API 20A |
| 68367 | 27082 ChEBI | trehalose | + | builds acid from | from API 20A |
| 68367 | 27897 ChEBI | tryptophan | - | energy source | from API 20A |
| 68367 | 16199 ChEBI | urea | - | hydrolysis | from API 20A |
| @ref | IND | URE | GLU | MAN | LAC | SAC | MAL | SAL | XYL | ARA | GEL | ESC | GLY | CEL | MNE | MLZ | RAF | SOR | RHA | TRE | CAT | Spores presentSPOR | GramGRAM | Morphology coccus="+" rod="-"COCC | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 489 | - | - | + | + | + | + | + | + | - | - | - | + | - | + | + | - | + | - | - | + | not determinedn.d. | not determinedn.d. | not determinedn.d. | not determinedn.d. |
Global distribution of 16S sequence AB595128 (>99% sequence identity) for Erysipelatoclostridium ramosum subclade from Microbeatlas ![]()
| @ref | Description | Assembly level | INSDC accession | BV-BRC accession | IMG accession | NCBI tax ID | Score | |
|---|---|---|---|---|---|---|---|---|
| 66792 | ASM1413169v1 assembly for Thomasclavelia ramosa DSM 1402 | complete | 445974 | 99.31 | ||||
| 124043 | ASM1602713v1 assembly for Thomasclavelia ramosa FDAARGOS_906 | complete | 1547 | 99.31 | ||||
| 67770 | ASM15448v1 assembly for Thomasclavelia ramosa DSM 1402 | scaffold | 445974 | 72.61 |
| @ref | Description | Accession | Length | Database | NCBI tax ID | |
|---|---|---|---|---|---|---|
| 20218 | C.ramosum 16S ribosomal RNA small subunit | M23731 | 1530 | 1547 | ||
| 20218 | Clostridium ramosum DSM 1402 16S ribosomal RNA gene, partial sequence | HM245949 | 829 | 445974 | ||
| 20218 | Clostridium ramosum strain DSM 1402 16S ribosomal RNA gene, partial sequence | HQ012012 | 927 | 445974 | ||
| 20218 | Clostridium ramosum 16S rRNA gene, strain DSM 1402 | X73440 | 1526 | 445974 | ||
| 489 | Clostridium ramosum gene for 16S ribosomal RNA, partial sequence, strain: JCM 1298 | AB595128 | 1488 | 1547 |
| @ref | Trait | Model | Prediction | Confidence in % | In training data |
|---|---|---|---|---|---|
| 125439 | oxygen_tolerance | BacteriaNetⓘ | facultative anaerobe | 98.52 | no |
| 125439 | gram_stain | BacteriaNetⓘ | positive | 76.40 | no |
| 125439 | motility | BacteriaNetⓘ | yes | 69.43 | no |
| 125439 | spore_formation | BacteriaNetⓘ | yes | 71.10 | no |
| @ref | Trait | Model | Prediction | Confidence in % | In training data |
|---|---|---|---|---|---|
| 125438 | gram-positive | gram-positiveⓘ | yes | 81.77 | no |
| 125438 | anaerobic | anaerobicⓘ | yes | 87.05 | no |
| 125438 | aerobic | aerobicⓘ | no | 98.75 | no |
| 125438 | spore-forming | spore-formingⓘ | no | 58.27 | no |
| 125438 | thermophilic | thermophileⓘ | no | 93.01 | yes |
| 125438 | flagellated | motile2+ⓘ | no | 80.77 | no |
| Topic | Title | Authors | Journal | DOI | Year | |
|---|---|---|---|---|---|---|
| Phylogeny | Reclassification of Clostridium cocleatum, Clostridium ramosum, Clostridium spiroforme and Clostridium saccharogumia as Thomasclavelia cocleata gen. nov., comb. nov., Thomasclavelia ramosa comb. nov., gen. nov., Thomasclavelia spiroformis comb. nov. and Thomasclavelia saccharogumia comb. nov. | Lawson PA, Saavedra Perez L, Sankaranarayanan K. | Int J Syst Evol Microbiol | 10.1099/ijsem.0.005694 | 2023 | |
| Bacterial microcompartments and energy metabolism drive gut colonization by Bilophila wadsworthia | Sayavedra L, Yasir M, Goldson A, Brion A, Le Gall G, Moreno-Gonzalez M, Altera A, Paxhia M, Warren M, Savva G, Turner A, Beraza N, Narbad A. | Nat Commun | 2025 | |||
| Chemical analysis of the Alphaproteobacterium strain MOLA1416 associated with the marine lichen Lichina pygmaea. | Parrot D, Intertaglia L, Jehan P, Grube M, Suzuki MT, Tomasi S. | Phytochemistry | 10.1016/j.phytochem.2017.10.005 | 2018 | ||
| Genetics | Effect of minocycline, methyl prednisolone, or combination treatment on the colonic bacterial population in a state of colonic inflammation using the murine dextran sulfate sodium model. | Khajah MA, Hawai S. | Microb Cell Fact | 10.1186/s12934-023-02242-8 | 2023 | |
| Genetics | Conservation and Evolution of the Sporulation Gene Set in Diverse Members of the Firmicutes. | Galperin MY, Yutin N, Wolf YI, Vera Alvarez R, Koonin EV. | J Bacteriol | 10.1128/jb.00079-22 | 2022 | |
| Association of germ-free mice with a simplified human intestinal microbiota results in a shortened intestine. | Slezak K, Krupova Z, Rabot S, Loh G, Levenez F, Descamps A, Lepage P, Dore J, Bellier S, Blaut M. | Gut Microbes | 10.4161/gmic.28203 | 2014 | ||
| Pathogenicity | Akkermansia muciniphila strain ATCC BAA-835 does not promote short-term intestinal inflammation in gnotobiotic interleukin-10-deficient mice. | Ring C, Klopfleisch R, Dahlke K, Basic M, Bleich A, Blaut M. | Gut Microbes | 10.1080/19490976.2018.1511663 | 2019 | |
| Metabolism | Clostridium ramosum regulates enterochromaffin cell development and serotonin release. | Mandic AD, Woting A, Jaenicke T, Sander A, Sabrowski W, Rolle-Kampcyk U, von Bergen M, Blaut M. | Sci Rep | 10.1038/s41598-018-38018-z | 2019 | |
| Metabolism | Clostridium ramosum promotes high-fat diet-induced obesity in gnotobiotic mouse models. | Woting A, Pfeiffer N, Loh G, Klaus S, Blaut M. | mBio | 10.1128/mbio.01530-14 | 2014 | |
| Alleviation of high fat diet-induced obesity by oligofructose in gnotobiotic mice is independent of presence of Bifidobacterium longum. | Woting A, Pfeiffer N, Hanske L, Loh G, Klaus S, Blaut M. | Mol Nutr Food Res | 10.1002/mnfr.201500249 | 2015 | ||
| Microbial co-habitation and lateral gene transfer: what transposases can tell us. | Hooper SD, Mavromatis K, Kyrpides NC. | Genome Biol | 10.1186/gb-2009-10-4-r45 | 2009 | ||
| Phylogeny | Diet-induced metabolic improvements in a hamster model of hypercholesterolemia are strongly linked to alterations of the gut microbiota. | Martinez I, Wallace G, Zhang C, Legge R, Benson AK, Carr TP, Moriyama EN, Walter J. | Appl Environ Microbiol | 10.1128/aem.00380-09 | 2009 | |
| Phylogeny | Thomasclavelia ramosa and alcohol-related hepatocellular carcinoma: a microbial culturomics study. | Magdy Wasfy R, Abdoulaye A, Borentain P, Mbaye B, Tidjani Alou M, Caputo A, Andrieu C, Mottola G, Levasseur A, Million M, Gerolami R. | Gut Pathog | 10.1186/s13099-025-00703-6 | 2025 | |
| Genetics | Altered gut microbiota in erectile dysfunction patients: a pilot study. | Su Q, Wang K, Luo Y, Tang Q. | Front Microbiol | 10.3389/fmicb.2025.1530014 | 2025 | |
| Limosilactobacillus fermentum, Lactococcus lactis and Thomasclavelia ramosa are enriched and Methanobrevibacter smithii is depleted in patients with non-alcoholic steatohepatitis. | Mbaye B, Wasfy RM, Alou MT, Borentain P, Andrieu C, Caputo A, Raoult D, Gerolami R, Million M. | Microb Pathog | 10.1016/j.micpath.2023.106160 | 2023 | ||
| Genetics | Limitations of MALDI-TOF MS in identifying anaerobic bacteremia: challenges in polymicrobial infections and the role of whole-genome sequencing. | Hosoda T, Suzuki M, Matsuno T, Matsui K, Ohyama K, Doi Y. | Microbiol Spectr | 10.1128/spectrum.01014-25 | 2025 | |
| Biochemical and structural characterization of the human gut microbiome metallopeptidase IgAse provides insight into its unique specificity for the Fab' region of IgA1 and IgA2. | Ramirez-Larrota JS, Juyoux P, Guerra P, Eckhard U, Gomis-Ruth FX. | PLoS Pathog | 10.1371/journal.ppat.1013292 | 2025 | ||
| Gut microbiome dynamics and functional shifts in healthy aging: insights from a metagenomic study. | Ai X, Huang C, Liu Q, Duan R, Ma X, Li L, Shu Z, Miao Y, Shen H, Lv Y, Jiang Z, Luo H, Long Z. | Front Microbiol | 10.3389/fmicb.2025.1629811 | 2025 | ||
| Phylogeny | Culture-based characterization of gut microbiota in inflammatory bowel disease. | Park H, Yeo S, Lee T, Han Y, Ryu CB, Huh CS. | Front Microbiol | 10.3389/fmicb.2025.1538620 | 2025 | |
| Co-Colonization of Non-difficile Clostridial Species in Antibiotic-Associated Diarrhea Caused by Clostridioides difficile. | Salas-Trevino D, Flores-Trevino S, Cisneros-Rendon C, Dominguez-Rivera CV, Camacho-Ortiz A. | Antibiotics (Basel) | 10.3390/antibiotics14040397 | 2025 | ||
| Metabolism | A Low-Gluten Diet Reduces the Abundance of Potentially Beneficial Bacteria in Healthy Adult Gut Microbiota | Delmas E, Bingula R, Del'homme C, Meunier N, Caille A, Lyon-Belgy N, Richard R, Do Couto M, Wittrant Y, Bernalier-Donadille A. | Nutrients | 2025 | ||
| Optogenetics-integrated gut organ culture system connects enteric neurons dynamics and gut homeostasis. | Naim G, Romano-Zadaka H, Amidror S, Jessula Levy D, Cohen A, Sochen C, Gilberg H, Farah N, Rudenko V, Yarden Y, Feng M, Tsentsarevsky R, Brodie Z, Reich Y, Simon A, Toister E, Shoval I, Armon L, Schiller M, Mandel Y, Biton M, Yissachar N. | Nat Commun | 10.1038/s41467-025-64995-7 | 2025 | ||
| Molecular basis of Fab-dependent IgA antibody recognition by gut-bacterial metallopeptidases. | Marquez-Monino MA, Martinez Gascuena A, Azzam T, Persson A, Manzanares-Gomez A, Aguillo-Urarte M, Brown TT, Montero-Sagarminaga A, Lood R, Naegeli A, Connell SR, Sastre DE, Sundberg EJ, Trastoy B. | EMBO J | 10.1038/s44318-025-00518-w | 2025 | ||
| Genetics | The microbiome-restorative potential of ibezapolstat for the treatment of Clostridioides difficile infection is predicted through variant PolC-type DNA polymerase III in Lachnospiraceae and Oscillospiraceae. | McPherson JK, Hurdle JG, Baker ML, Hussain T, Kumar A, Garey KW. | Antimicrob Agents Chemother | 10.1128/aac.01679-24 | 2025 | |
| Non-stochastic reassembly of a metabolically cohesive gut consortium shaped by N-acetyl-lactosamine-enriched fibers. | Moore M, Whittington HD, Knickmeyer R, Azcarate-Peril MA, Bruno-Barcena JM. | Gut Microbes | 10.1080/19490976.2024.2440120 | 2025 | ||
| Genetics | Coupling culturomics and metagenomics sequencing to characterize the gut microbiome of patients with cancer treated with immune checkpoint inhibitors. | Diop K, Mbaye B, Nili S, Filin A, Benlaifaoui M, Malo J, Renaud AS, Belkaid W, Hunter S, Messaoudene M, Lee KA, Elkrief A, Routy B. | Gut Pathog | 10.1186/s13099-025-00694-4 | 2025 | |
| Seeding and feeding: nutrition and birth-associated exposures shape gut microbiome assembly in breastfed infants. | Stinson LF, Norrish I, Mhembere F, Cheema AS, Mullally CA, Payne MS, Geddes DT. | Gut Microbes | 10.1080/19490976.2025.2557981 | 2025 | ||
| Metabolism | Coenzyme A metabolism: a key driver of gut microbiota dynamics and metabolic profiles. | Bottcher J, Sibon OCM, El Aidy S. | FEMS Microbiol Rev | 10.1093/femsre/fuaf051 | 2025 | |
| In vitro activity of fidaxomicin and combinations of fidaxomicin with other antibiotics against Clostridium perfringens strains isolated from dogs and cats. | Alvarez-Perez S, Anega B, Blanco JL, Hernandez M, Garcia ME. | BMC Vet Res | 10.1186/s12917-023-03801-2 | 2023 | ||
| Food colorant brilliant blue causes persistent functional and structural changes in an in vitro simplified microbiota model system. | Castaneda-Monsalve V, Haange SB, Frohlich LF, Fu Q, Rolle-Kampczyk U, von Bergen M, Jehmlich N. | ISME Commun | 10.1093/ismeco/ycaf050 | 2025 | ||
| Phylogeny | Microbiota analysis of perimenopausal women experiencing recurrent vaginitis in conjunction with urinary tract infection. | Bi Y, Wang Y, Li W, Chen Y, Qin J, Zheng H. | BMC Microbiol | 10.1186/s12866-024-03709-3 | 2025 | |
| Increased fecal ethanol and enriched ethanol-producing gut bacteria Limosilactobacillus fermentum, Enterocloster bolteae, Mediterraneibacter gnavus and Streptococcus mutans in nonalcoholic steatohepatitis. | Mbaye B, Magdy Wasfy R, Borentain P, Tidjani Alou M, Mottola G, Bossi V, Caputo A, Gerolami R, Million M. | Front Cell Infect Microbiol | 10.3389/fcimb.2023.1279354 | 2023 | ||
| Serotypes, Antimicrobial Susceptibility, and Potential Mechanisms of Resistance Gene Transfer in Erysipelothrix rhusiopathiae Strains from Waterfowl in Poland. | Dec M, Nowak T, Webster J, Wodz K. | Int J Mol Sci | 10.3390/ijms252212192 | 2024 | ||
| Proton-pump inhibitors increase C. difficile infection risk by altering pH rather than by affecting the gut microbiome based on a bioreactor model. | Schumacher J, Muller P, Sulzer J, Faber F, Molitor B, Maier L. | Gut Microbes | 10.1080/19490976.2025.2519697 | 2025 | ||
| Fasting elicits gut microbiome signature changes that extend to type 1 diabetes patients | Graef F, Berger B, Bahr L, Stange R, Michalsen A, Paul F, Vallance B, Jacobson K. | Front Endocrinol (Lausanne) | 2025 | |||
| Microbiota modulate immune cell populations and drive dynamic structural changes in gut-associated lymphoid tissue | Jan P, Nikola M, Liliana T, Karolina K, Valeria G, Zdenek Z, Tomas H, Anna M, Dagmar S, Martin S, Marianne B, Jan C. | Gut microbes | 2025 | |||
| Oat Beta-Glucans Modulate the Gut Microbiome, Barrier Function, and Immune Responses in an In Vivo Model of Early-Stage Colorectal Cancer. | Guzowska M, Dziendzikowska K, Kopiasz L, Gajewska M, Wilczak J, Harasym J, Czerwinska M, Gromadzka-Ostrowska J. | Int J Mol Sci | 10.3390/ijms252413586 | 2024 | ||
| Identification and distribution of new candidate T6SS effectors encoded in Salmonella Pathogenicity Island 6. | Blondel CJ, Amaya FA, Bustamante P, Santiviago CA, Pezoa D. | Front Microbiol | 10.3389/fmicb.2023.1252344 | 2023 | ||
| High-throughput screening of the effects of 90 xenobiotics on the simplified human gut microbiota model (SIHUMIx): a metaproteomic and metabolomic study | Castaneda-Monsalve V, Frohlich L, Haange S, Homsi M, Rolle-Kampczyk U, Fu Q, von Bergen M, Jehmlich N. | Front Microbiol | 2024 | |||
| Genetics | Exclusive enteral nutrition initiates individual protective microbiome changes to induce remission in pediatric Crohn's disease. | Hacker D, Siebert K, Smith BJ, Kohler N, Riva A, Mahapatra A, Heimes H, Nie J, Metwaly A, Holz H, Manz Q, De Zen F, Heetmeyer J, Socas K, Le Thi G, Meng C, Kleigrewe K, Pauling JK, Neuhaus K, List M, Pollard KS, Schwerd T, Haller D. | Cell Host Microbe | 10.1016/j.chom.2024.10.001 | 2024 | |
| Phylogeny | Bacteriostatic effect of orally administered bovine lactoferrin on proliferation of Clostridium species in the gut of mice fed bovine milk. | Teraguchi S, Shin K, Ozawa K, Nakamura S, Fukuwatari Y, Tsuyuki S, Namihira H, Shimamura S | Appl Environ Microbiol | 10.1128/aem.61.2.501-506.1995 | 1995 | |
| Phylogeny | Rise of Microbial Culturomics: Noncontiguous Finished Genome Sequence and Description of Beduini massiliensis gen. nov., sp. nov. | Mourembou G, Yasir M, Azhar EI, Lagier JC, Bibi F, Jiman-Fatani AA, Helmy N, Robert C, Rathored J, Fournier PE, Raoult D, Million M. | OMICS | 10.1089/omi.2015.0143 | 2015 | |
| Phylogeny | Tannockella kyphosi gen. nov., sp. nov., a member of the family Erysipelotrichaceae, isolated from the hindgut of the marine herbivorous fish Kyphosus sydneyanus. | Pardesi B, Roberton AM, Wollmuth EM, Angert ER, Rosendale DI, White WL, Clements KD | Int J Syst Evol Microbiol | 10.1099/ijsem.0.005374 | 2022 |
| #489 | Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 1402 |
| #20215 | Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 ) |
| #20218 | Verslyppe, B., De Smet, W., De Baets, B., De Vos, P., Dawyndt P.: StrainInfo introduces electronic passports for microorganisms.. Syst Appl Microbiol. 37: 42 - 50 2014 ( DOI 10.1016/j.syapm.2013.11.002 , PubMed 24321274 ) |
| #47909 | Culture Collection University of Gothenburg (CCUG) ; Curators of the CCUG; CCUG 24038 |
| #66792 | Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) . |
| #67770 | Japan Collection of Microorganism (JCM) ; Curators of the JCM; |
| #68367 | Automatically annotated from API 20A . |
| #69479 | João F Matias Rodrigues, Janko Tackmann,Gregor Rot, Thomas SB Schmidt, Lukas Malfertheiner, Mihai Danaila,Marija Dmitrijeva, Daniela Gaio, Nicolas Näpflin and Christian von Mering. University of Zurich.: MicrobeAtlas 1.0 beta . |
| #124043 | Isabel Schober, Julia Koblitz: Data extracted from sequence databases, automatically matched based on designation and taxonomy . |
| #125438 | Julia Koblitz, Lorenz Christian Reimer, Rüdiger Pukall, Jörg Overmann: Predicting bacterial phenotypic traits through improved machine learning using high-quality, curated datasets. 2024 ( DOI 10.1101/2024.08.12.607695 ) |
| #125439 | Philipp Münch, René Mreches, Martin Binder, Hüseyin Anil Gündüz, Xiao-Yin To, Alice McHardy: deepG: Deep Learning for Genome Sequence Data. R package version 0.3.1 . |
| #126262 | A. Lissin, I. Schober, J. F. Witte, H. Lüken, A. Podstawka, J. Koblitz, B. Bunk, P. Dawyndt, P. Vandamme, P. de Vos, J. Overmann, L. C. Reimer: StrainInfo—the central database for linked microbial strain identifiers. ( DOI 10.1093/database/baaf059 ) |
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