Name: Chlamydia trachomatis UW-3/Cx
Creator: BacDive
License: http://creativecommons.org/licenses/by-nc/4.0/

Strain identifier

BacDive ID: 2393

Type strain:

Species: Chlamydia trachomatis

Strain Designation: UW-3/Cx

Culture col. no.: DSM 19411, ATCC VR-885

Strain history: <- S. Gronow, Leibniz-Institut DSMZ GmbH, Braunschweig, Germany; <- H. Brade; <- ATCC; ATCC VR-885 <- S.-P. Wang; UW-3/Cx

NCBI tax ID(s): 813 (species)

SI-ID 408097

DSM 19411

Other strains from Chlamydia trachomatis

C. trachomatis HAR-13, DSM 19440, ATCC VR-571B (type strain)
C. trachomatis 434, DSM 19102, ATCC VR-902B
C. trachomatis Bour, DSM 19131, ATCC VR-348B
C. trachomatis IC-Cal-3, DSM 19410, ATCC VR-346

Section

Chlamydia trachomatis UW-3/Cx is a mesophilic bacterium that was isolated from human cervix, asymptomatic.

mesophilic
16S sequence
Bacteria

Information on the name and the taxonomic classification. Name and taxonomic classification

	Last LPSN update	14-12-2023 (DD-MM-YYYY)
	Domain	"Bacteria"
	Phylum	*Chlamydiota*
	Class	*Chlamydiia*
	Order	*Chlamydiales*
	Family	*Chlamydiaceae*
	Genus	*Chlamydia*
	Species	**Chlamydia trachomatis**
	Full Scientific Name (LPSN)	Chlamydia trachomatis (Busacca 1935) Rake 1957 (Approved Lists 1980)

Synonym

"Rickettsia trachomae"

Information on morphological and physiological properties Morphology

[Ref.: #8092]

Incubation period

3-7 days

Information on culture and growth conditions Culture and growth conditions

[Ref.: #8092]

Culture medium

CULTIVATION MEDIUM FOR CHLAMYDIAE (DSMZ Medium 1193)

[Ref.: #8092]

Culture medium growth

[Ref.: #8092]

Culture medium link

Medium recipe at MediaDive

[Ref.: #8092]

Culture medium composition

expand / minimize

	Temperatures	Kind of temperature		Temperature
[Ref.: #8092]			growth	37 °C

[Ref.: #8092]

Temperature range

mesophilic

Information on isolation source, the sampling and environmental conditions Isolation, sampling and environmental information

[Ref.: #8092]	Sample type/isolated from	human cervix, asymptomatic
[Ref.: #8092]	Country	USA
[Ref.: #8092]	Country ISO 3 Code	USA
[Ref.: #8092]	Continent	North America
* marker position based on {}

Isolation sources categories

#Host

#Human

What are isolation sources categories?

[Ref.: #69479]

Global distribution of 16S sequence CP002054 (>99% sequence identity) for Chlamydia trachomatis from Microbeatlas

Aquatic Samples	198
Soil Samples	233
Animal Samples	4312
Plant Samples	37
Total Samples	4780

Information on possible application of the strain and its possible interaction with e.g. potential hosts Safety information

[Ref.: #8092]

Biosafety level

Risk group (German classification)
According to TRBA 466

Information on genomic background e.g. entries in nucleic sequence databass Sequence information

16S Sequence information:

	Sequence accession description	Seq. accession number	Sequence length (bp)	Sequence database	Associated NCBI tax ID
[Ref.: #8092]	Chlamydia trachomatis D-LC, complete genome	CP002054	1042520	ENA	759364 tax ID

Availability in culture collections External links

[Ref.: #8092]

Culture collection no.

DSM 19411, ATCC VR-885

[Ref.: #71948]

SI-ID 408097

Literature:

Only first 10 entries are displayed. Click here to see all.

Topic	Title	Authors	Journal	DOI	Year
Metabolism	Crystal structure of an inorganic pyrophosphatase from Chlamydia trachomatis D/UW-3/Cx.	Maddy J, Staker BL, Subramanian S, Abendroth J, Edwards TE, Myler PJ, Hybiske K, Asojo OA	Acta Crystallogr F Struct Biol Commun	10.1107/S2053230X22002138	2022	*
Metabolism	Human genital antibody-mediated inhibition of Chlamydia trachomatis infection and evidence for ompA genotype-specific neutralization.	Ardizzone CM, Albritton HL, Lillis RA, Bagnetto CEL, Shen L, Cavacini LA, Kozlowski PA, Quayle AJ	PLoS One	10.1371/journal.pone.0258759	2021	*
Phenotype	Chlamydial clinical isolates show subtle differences in persistence phenotypes and growth in vitro.	Thomas M, Lawrence A, Kroon S, Vodstrcil LA, Phillips S, Hocking JS, Timms P, Huston WM	Access Microbiol	10.1099/acmi.0.000204	2021	*
Enzymology	A Recombinant Chlamydia trachomatis MOMP Vaccine Elicits Cross-serogroup Protection in Mice Against Vaginal Shedding and Infertility.	Tifrea DF, Pal S, de la Maza LM	J Infect Dis	10.1093/infdis/jiz438	2020	*
Pathogenicity	Transcervical Inoculation with Chlamydia trachomatis Induces Infertility in HLA-DR4 Transgenic and Wild-Type Mice.	Pal S, Tifrea DF, Zhong G, de la Maza LM	Infect Immun	10.1128/IAI.00722-17	2017	*
Pathogenicity	Genome analysis of Chlamydia trachomatis for functional characterization of hypothetical proteins to discover novel drug targets.	Turab Naqvi AA, Rahman S, Rubi, Zeya F, Kumar K, Choudhary H, Jamal MS, Kim J, Hassan MI	Int J Biol Macromol	10.1016/j.ijbiomac.2016.12.045	2016	*
Phylogeny	Comparable Genital Tract Infection, Pathology, and Immunity in Rhesus Macaques Inoculated with Wild-Type or Plasmid-Deficient Chlamydia trachomatis Serovar D.	Qu Y, Frazer LC, O'Connell CM, Tarantal AF, Andrews CW Jr, O'Connor SL, Russell AN, Sullivan JE, Poston TB, Vallejo AN, Darville T	Infect Immun	10.1128/IAI.00841-15	2015	*
Metabolism	In vitro antichlamydial activity of garenoxacin against Chlamydia trachomatis.	Futakuchi N, Nakatani M, Takahata M, Mitsuyama J	J Infect Chemother	10.1007/s10156-011-0345-8	2011	*
Metabolism	Toll-like receptor 2 activation by Chlamydia trachomatis is plasmid dependent, and plasmid-responsive chromosomal loci are coordinately regulated in response to glucose limitation by C. trachomatis but not by C. muridarum.	O'Connell CM, AbdelRahman YM, Green E, Darville HK, Saira K, Smith B, Darville T, Scurlock AM, Meyer CR, Belland RJ	Infect Immun	10.1128/IAI.01118-10	2011	*
Pathogenicity	Potential of a novel polyherbal formulation BASANT for prevention of Chlamydia trachomatis infection.	Bhengraj AR, Dar SA, Talwar GP, Mittal A	Int J Antimicrob Agents	10.1016/j.ijantimicag.2008.02.010	2008	*
Pathogenicity	In vitro inhibitory effects of hinokitiol on proliferation of Chlamydia trachomatis.	Yamano H, Yamazaki T, Sato K, Shiga S, Hagiwara T, Ouchi K, Kishimoto T	Antimicrob Agents Chemother	10.1128/AAC.49.6.2519-2521.2005	2005	*
Pathogenicity	Biosynthesized tea polyphenols inactivate Chlamydia trachomatis in vitro.	Yamazaki T, Kishimoto T, Shiga S, Sato K, Hagiwara T, Inoue M, Sasaki N, Ouchi K, Hara Y	Antimicrob Agents Chemother	10.1128/AAC.49.6.2501-2503.2005	2005	*
Pathogenicity	Emergence of resistance to rifampin and rifalazil in Chlamydophila pneumoniae and Chlamydia trachomatis.	Kutlin A, Kohlhoff S, Roblin P, Hammerschlag MR, Riska P	Antimicrob Agents Chemother	10.1128/AAC.49.3.903-907.2005	2005	*
Pathogenicity	Inactivation of Chlamydia trachomatis and Chlamydia (Chlamydophila) pneumoniae by ozone.	Yamazaki T, Inoue M, Ogawa M, Shiga S, Kishimoto T, Hagiwara T, Matsumoto T, Hayashi T	Lett Appl Microbiol	10.1111/j.1472-765X.2004.01506.x	2004	*
Pathogenicity	In vitro inhibitory effects of tea polyphenols on the proliferation of Chlamydia trachomatis and Chlamydia pneumoniae.	Yamazaki T, Inoue M, Sasaki N, Hagiwara T, Kishimoto T, Shiga S, Ogawa M, Hara Y, Matsumoto T	Jpn J Infect Dis		2003	*
Pathogenicity	Detection of antimicrobial-treated Chlamydia trachomatis with Amplicor PCR test kit.	Takahashi S, Hagiwara T, Shiga S, Hirose T, Tsukamoto T	J Infect Chemother	10.1007/s101560070005	2000	*
Pathogenicity	The inhibitory effect of phosphate on the ligase chain reaction used for detecting Chlamydia trachomatis.	Notomi T, Ikeda Y, Okadome A, Nagayama A	J Clin Pathol	10.1136/jcp.51.4.306	1998	*
Pathogenicity	Detection of Chlamydia pneumoniae by polymerase chain reaction.	Campbell LA, Perez Melgosa M, Hamilton DJ, Kuo CC, Grayston JT	J Clin Microbiol	10.1128/jcm.30.2.434-439.1992	1992	*
Pathogenicity	In vitro and in vivo activities of sparfloxacin, other quinolones, and tetracyclines against Chlamydia trachomatis.	Nakata K, Maeda H, Fujii A, Arakawa S, Umezu K, Kamidono S	Antimicrob Agents Chemother	10.1128/AAC.36.1.188	1992	*
Enzymology	Vaccination with the recombinant major outer membrane protein elicits antibodies to the constant domains and induces cross-serovar protection against intranasal challenge with Chlamydia trachomatis.	Tifrea DF, Ralli-Jain P, Pal S, de la Maza LM	Infect Immun	10.1128/IAI.00734-12	2013	*
Phylogeny	Differences in infectivity and induction of infertility: a comparative study of Chlamydia trachomatis strains in the murine model.	Carmichael JR, Tifrea D, Pal S, de la Maza LM	Microbes Infect	10.1016/j.micinf.2012.12.001	2012	*
	Enhanced neutrophil longevity and recruitment contribute to the severity of oviduct pathology during Chlamydia muridarum infection.	Frazer LC, O'Connell CM, Andrews CW Jr, Zurenski MA, Darville T	Infect Immun	10.1128/IAI.05535-11	2011	*

References

#8092

Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 19411

#20215

Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 )

#69479

João F Matias Rodrigues, Janko Tackmann,Gregor Rot, Thomas SB Schmidt, Lukas Malfertheiner, Mihai Danaila,Marija Dmitrijeva, Daniela Gaio, Nicolas Näpflin and Christian von Mering. University of Zurich.: MicrobeAtlas 1.0 beta .

#71948

Reimer, L.C., Lissin, A.,Schober, I., Witte,J.F., Podstawka, A., Lüken, H., Bunk, B.,Overmann, J.: StrainInfo: A central database for resolving microbial strain identifiers . ( DOI 10.60712/SI-ID408097.1 )

* These data were automatically processed and therefore are not curated

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