Bartonella vinsonii subsp. berkhoffii (DSM 28220, ATCC 51672, CCUG 45779)

Name: Bartonella vinsonii subsp. berkhoffii (DSM 28220, ATCC 51672, CCUG 45779)
Creator: BacDive
License: http://creativecommons.org/licenses/by/4.0/

BacDive ID 23778

Type strain

Strain Designation 93-CO1, 93-C01

Culture col. no. DSM 28220 ATCC 51672 CCUG 45779 CIP 104960 93-CO1 1 more

NCBI tax ID(s) 1408318 40933

Special Collections DSMZ CCUG CIP

History DSMZ <- CIP <- E. B. Breitschwerdt; 93-CO1 CIP <- 1996, E.B. Breitschwerdt, Coll. Vet. Med., Raleigh, NC, USA: strain 93-C01

Links

Bartonella vinsonii subsp. berkhoffii 93-CO1 is a microaerophile, Gram-negative, rod-shaped bacterium that was isolated from canine blood.

Gram-negative rod-shaped microaerophile genome sequence 16S sequence Bacteria

Name and taxonomic classification

SI-ID 43111

ATCC 51672,CIP 104960,CCUG 45779,DSM 28220

@ref 20215

Last LPSN update 2026-05-29 08:30:29

Domain Bacteria

Phylum Pseudomonadota

Class Alphaproteobacteria

Order Hyphomicrobiales

Family Bartonellaceae

Genus Bartonella

Species Bartonella vinsonii subsp. berkhoffii

Full scientific name Bartonella vinsonii subsp. berkhoffii Kordick et al. 1996

Morphology

Cell morphology

@ref	Gram stain	Cell shape	Confidence
125439	negative		99.005
125438	negative		98.783
123849	negative	rod-shaped

Colony morphology

@ref	Incubation period	Hemolysis ability
20448	1-2 days
56921	3 days
123849		0

Culture and growth conditions

Culture medium

@ref	Name	Medium link	Composition
20448	COLUMBIA BLOOD AGAR (DSMZ Medium 429)	Medium recipe at MediaDive	Name: COLUMBIA BLOOD AGAR (DSMZ Medium 429; with strain-specific modifications) Composition: Horse blood 100.0 g/l Columbia agar base
34222	MEDIUM 45 - for Columbia agar with sheep blood		Distilled water make up to (1000.000 ml);Columbia agar (39.000 g);Sheepblood (100.000 ml)
123849	CIP Medium 45	Medium recipe at CIP

Culture temp

@ref	Growth	Type	Temperature (°C)
20448	positive	growth	37
34222	positive	growth	37
56921	positive	growth	37
123849	positive	growth	30-37
123849	negative	growth	25

Physiology and metabolism

Oxygen tolerance

@ref	Oxygen tolerance	Confidence
56921	microaerophile
125439	facultative anaerobe	94.56

Spore formation

@ref	Spore formation	Confidence
125439		99.984
125438		93.955

Halophily

@ref	Salt	Growth	Tested relation	Concentration
123849	NaCl	positive	growth	0 %
123849	NaCl		growth	2 %
123849	NaCl		growth	4 %
123849	NaCl		growth	6 %
123849	NaCl		growth	8 %
123849	NaCl		growth	10 %

Metabolite utilization

@ref	Chebi-ID	Metabolite	Utilization activity	Kind of utilization tested
68371	27613 ChEBI	amygdalin	-	builds acid from	from API 50CH acid
68371	18305 ChEBI	arbutin	-	builds acid from	from API 50CH acid
68371	17057 ChEBI	cellobiose	-	builds acid from	from API 50CH acid
68371	17108 ChEBI	D-arabinose	-	builds acid from	from API 50CH acid
68371	18333 ChEBI	D-arabitol	-	builds acid from	from API 50CH acid
68371	15824 ChEBI	D-fructose	-	builds acid from	from API 50CH acid
68371	28847 ChEBI	D-fucose	-	builds acid from	from API 50CH acid
68371	12936 ChEBI	D-galactose	-	builds acid from	from API 50CH acid
68371	17634 ChEBI	D-glucose	-	builds acid from	from API 50CH acid
68371	62318 ChEBI	D-lyxose	-	builds acid from	from API 50CH acid
68371	16899 ChEBI	D-mannitol	-	builds acid from	from API 50CH acid
68371	16024 ChEBI	D-mannose	-	builds acid from	from API 50CH acid
68371	16988 ChEBI	D-ribose	-	builds acid from	from API 50CH acid
68371	17924 ChEBI	D-sorbitol	-	builds acid from	from API 50CH acid
68371	16443 ChEBI	D-tagatose	-	builds acid from	from API 50CH acid
68371	65327 ChEBI	D-xylose	-	builds acid from	from API 50CH acid
68371	17113 ChEBI	erythritol	-	builds acid from	from API 50CH acid
123849	4853 ChEBI	esculin	-	hydrolysis
68371	4853 ChEBI	esculin	-	builds acid from	from API 50CH acid
68371	16813 ChEBI	galactitol	-	builds acid from	from API 50CH acid
68371	28066 ChEBI	gentiobiose	-	builds acid from	from API 50CH acid
68371	24265 ChEBI	gluconate	-	builds acid from	from API 50CH acid
68371	17754 ChEBI	glycerol	-	builds acid from	from API 50CH acid
68371	28087 ChEBI	glycogen	-	builds acid from	from API 50CH acid
123849	606565 ChEBI	hippurate	+	hydrolysis
68371	15443 ChEBI	inulin	-	builds acid from	from API 50CH acid
68371	30849 ChEBI	L-arabinose	-	builds acid from	from API 50CH acid
68371	18403 ChEBI	L-arabitol	-	builds acid from	from API 50CH acid
68371	18287 ChEBI	L-fucose	-	builds acid from	from API 50CH acid
68371	62345 ChEBI	L-rhamnose	-	builds acid from	from API 50CH acid
68371	17266 ChEBI	L-sorbose	-	builds acid from	from API 50CH acid
68371	65328 ChEBI	L-xylose	-	builds acid from	from API 50CH acid
68371	17716 ChEBI	lactose	-	builds acid from	from API 50CH acid
68371	17306 ChEBI	maltose	-	builds acid from	from API 50CH acid
68371	6731 ChEBI	melezitose	-	builds acid from	from API 50CH acid
68371	28053 ChEBI	melibiose	-	builds acid from	from API 50CH acid
68371	320061 ChEBI	methyl alpha-D-glucopyranoside	-	builds acid from	from API 50CH acid
68371	43943 ChEBI	methyl alpha-D-mannoside	-	builds acid from	from API 50CH acid
68371	74863 ChEBI	methyl beta-D-xylopyranoside	-	builds acid from	from API 50CH acid
68371	17268 ChEBI	myo-inositol	-	builds acid from	from API 50CH acid
68371	59640 ChEBI	N-acetylglucosamine	-	builds acid from	from API 50CH acid
123849	17632 ChEBI	nitrate	-	reduction
123849	16301 ChEBI	nitrite	-	reduction
68371	0 ChEBI	Potassium 2-ketogluconate	-	builds acid from	from API 50CH acid
68371	0 ChEBI	Potassium 5-ketogluconate	-	builds acid from	from API 50CH acid
68371	16634 ChEBI	raffinose	-	builds acid from	from API 50CH acid
68371	15963 ChEBI	ribitol	-	builds acid from	from API 50CH acid
68371	17814 ChEBI	salicin	-	builds acid from	from API 50CH acid
68371	28017 ChEBI	starch	-	builds acid from	from API 50CH acid
68371	17992 ChEBI	sucrose	-	builds acid from	from API 50CH acid
68371	27082 ChEBI	trehalose	-	builds acid from	from API 50CH acid
68371	32528 ChEBI	turanose	-	builds acid from	from API 50CH acid
68371	17151 ChEBI	xylitol	-	builds acid from	from API 50CH acid

Metabolite production

@ref	Chebi-ID	Metabolite	Production
123849	35581 ChEBI	indole

Metabolite tests

@ref	Chebi-ID	Metabolite	Voges-proskauer-test	Methylred-test
123849	15688 ChEBI	acetoin	-
123849	17234 ChEBI	glucose		-

Enzymes

@ref	Value	Activity	Ec
68382	acid phosphatase	-	3.1.3.2	from API zym
123849	alcohol dehydrogenase	-	1.1.1.1
68382	alkaline phosphatase	+	3.1.3.1	from API zym
68382	alpha-chymotrypsin	-	3.4.21.1	from API zym
68382	alpha-fucosidase	-	3.2.1.51	from API zym
68382	alpha-galactosidase	-	3.2.1.22	from API zym
68382	alpha-glucosidase	+	3.2.1.20	from API zym
68382	alpha-mannosidase	-	3.2.1.24	from API zym
68382	beta-galactosidase	-	3.2.1.23	from API zym
123849	beta-galactosidase	+	3.2.1.23
68382	beta-glucosidase	-	3.2.1.21	from API zym
68382	beta-glucuronidase	-	3.2.1.31	from API zym
68382	cystine arylamidase	-	3.4.11.3	from API zym
68382	esterase (C 4)	+		from API zym
68382	esterase lipase (C 8)	+		from API zym
123849	gamma-glutamyltransferase	+	2.3.2.2
123849	gelatinase	-
68382	leucine arylamidase	+	3.4.11.1	from API zym
68382	lipase (C 14)	-		from API zym
123849	lysine decarboxylase	-	4.1.1.18
68382	N-acetyl-beta-glucosaminidase	-	3.2.1.52	from API zym
68382	naphthol-AS-BI-phosphohydrolase	+		from API zym
123849	ornithine decarboxylase	-	4.1.1.17
123849	oxidase	-
123849	phenylalanine ammonia-lyase	-	4.3.1.24
68382	trypsin	-	3.4.21.4	from API zym
123849	tryptophan deaminase	-
123849	urease	-	3.5.1.5
68382	valine arylamidase	-		from API zym

API zym

@ref	Control	Alkaline phosphatase	Esterase (C 4)	2-naphtyl caprylateEsterase Lipase (C 8)	Lipase (C 14)	L-leucyl-2-naphthylamideLeucine arylamidase	L-valyl-2-naphthylamideValine arylamidase	L-cystyl-2-naphthylamideCystine arylamidase	Trypsin	alpha- Chymotrypsin	Acid phosphatase	Naphthol-AS-BI-phosphateNaphthol-AS-BI-phosphohydrolase	alpha- Galactosidase	beta- Galactosidase	beta- Glucuronidase	alpha- Glucosidase	beta- Glucosidase	N-acetyl-beta- glucosaminidase	alpha- Mannosidase	alpha- Fucosidase
123849	-	+	+	+	-	+	-	-	-	-	-	+	-	-	-	+	-	-	-	-

API 50CHac

@ref	ControlQ	GLY	ERY	DARA	LARA	RIB	DXYL	LXYL	ADO	MDX	GAL	GLU	FRU	MNE	SBE	RHA	DUL	INO	MAN	SOR	MDM	MDG	NAG	AMY	ARB	ESC	SAL	CEL	MAL	LAC	MEL	SAC	TRE	INU	MLZ	RAF	AMD	GLYG	XLT	GEN	TUR	LYX	TAG	DFUC	LFUC	DARL	LARL	GNT	2KG	5KG
123849	not determinedn.d.	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-

Isolation, sampling and environmental information

Isolation source categories

Cat1	Cat2	Cat3
#Host	#Mammals	#Canidae (Dog)
#Host Body Product	#Fluids	#Blood

Isolation

@ref	Sample type	Geographic location	Country	Country ISO 3 Code	Continent	Isolation date	Sampling date
20448	canine blood
56921	Canine blood		USA	USA	North America		1993
123849	Animal, Canine, blood	North Carolina	United States of America	USA	North America	1993

Taxonmaps

69479

Global distribution of 16S sequence L35052 (>99% sequence identity) for Bartonella from Microbeatlas

Aquatic Samples	2
Soil Samples	3
Animal Samples	67
Plant Samples	0
Total Samples	72

Interaction and safety

Risk assessment

@ref	Biosafety level	Biosafety level comment
20448	2	Risk group (German classification)
123849	2	Risk group (French classification)

Sequence information

Genome sequences

@ref	Description	Assembly level	INSDC accession	BV-BRC accession	IMG accession	NCBI tax ID	Score
66792	ASM51810v1 assembly for Bartonella vinsonii subsp. berkhoffii ATCC 51672	scaffold	GCA_000518105	1408318.3	2545555862	1408318	65.45
66792	Bartonella_vinsonii_subsp_berkhoffii_CIP_104960 assembly for Bartonella vinsonii subsp. berkhoffii ATCC 51672 CIP 104960	scaffold	GCA_902825225	1408318.6	8003388158	1408318	0

16S sequences

@ref	Description	Accession	Length	Database	NCBI tax ID
20448	Bartonella vinsonii subsp. berkhoffii 16S ribosomal RNA gene, partial sequence	L35052	1432		40933

Genome-based predictions

Predictions

Predictions from Deep Learning for Genome Sequence Data. R package version 0.3.1 based on: ASM51810v1 assembly for Bartonella vinsonii subsp. berkhoffii ATCC 51672
BV-BRC: 1408318.3

@ref	Trait	Model	Prediction	Confidence in %	In training data
125439	oxygen_tolerance	BacteriaNetⓘ	facultative anaerobe	94.56	no
125439	motility	BacteriaNetⓘ	yes	59.00	no
125439	gram_stain	BacteriaNetⓘ	negative	99.01	no
125439	spore_formation	BacteriaNetⓘ	no	99.98	no

Predictions from bacterial phenotypic traits through improved machine learning using high-quality, curated datasets based on: Bartonella vinsonii subsp. berkhoffii ATCC 51672 CIP 104960
NCBI: GCA_902825225.1

@ref	Trait	Model	Prediction	Confidence in %	In training data
125438	gram-positive	gram-positiveⓘ	no	98.78	no
125438	anaerobic	anaerobicⓘ	no	89.43	yes
125438	aerobic	aerobicⓘ	no	83.20	yes
125438	spore-forming	spore-formingⓘ	no	93.96	no
125438	thermophilic	thermophileⓘ	no	94.55	yes
125438	flagellated	motile2+ⓘ	no	80.58	no

Literature

Topic	Title	Authors	Journal	DOI	Year
	Laboratory Diagnosis of 37 Cases of Bartonella Endocarditis Based on Enzyme Immunoassay and Real-Time PCR.	Shapira L, Rasis M, Binsky Ehrenreich I, Maor Y, Katchman EA, Treves A, Velan A, Halutz O, Graidy-Varon M, Leibovitch C, Maisler N, Ephros M, Giladi M.	J Clin Microbiol	10.1128/jcm.02217-20	2021
Enzymology	Molecular documentation of Bartonella infection in dogs in Greece and Italy.	Diniz PP, Billeter SA, Otranto D, De Caprariis D, Petanides T, Mylonakis ME, Koutinas AF, Breitschwerdt EB.	J Clin Microbiol	10.1128/jcm.00082-09	2009
Enzymology	Infection of domestic dogs in peru by zoonotic bartonella species: a cross-sectional prevalence study of 219 asymptomatic dogs.	Diniz PP, Morton BA, Tngrian M, Kachani M, Barron EA, Gavidia CM, Gilman RH, Angulo NP, Brenner EC, Lerner R, Chomel BB.	PLoS Negl Trop Dis	10.1371/journal.pntd.0002393	2013
Enzymology	Isolation of a new subspecies, Bartonella vinsonii subsp. arupensis, from a cattle rancher: identity with isolates found in conjunction with Borrelia burgdorferi and Babesia microti among naturally infected mice.	Welch DF, Carroll KC, Hofmeister EK, Persing DH, Robison DA, Steigerwalt AG, Brenner DJ.	J Clin Microbiol	10.1128/jcm.37.8.2598-2601.1999	1999
Phylogeny	Genetic classification and differentiation of Bartonella species based on comparison of partial ftsZ gene sequences.	Zeaiter Z, Liang Z, Raoult D.	J Clin Microbiol	10.1128/jcm.40.10.3641-3647.2002	2002
Enzymology	Relationship between degenerative joint disease, pain, and Bartonella spp. seroreactivity in domesticated cats.	Tomas A, Pultorak EL, Gruen ME, Gruen ME, Breitschwerdt EB, Lascelles BD.	J Vet Intern Med	10.1111/jvim.12495	2015
Enzymology	Seroepidemiology of Bartonella vinsonii subsp. berkhoffii infection in California coyotes, 1994-1998.	Chang C, Yamamoto K, Chomel BB, Kasten RW, Simpson DC, Smith CR, Kramer VL.	Emerg Infect Dis	10.3201/eid0505.990514	1999
	Production of Bartonella genus-specific monoclonal antibodies.	Liang Z, La Scola B, Lepidi H, Raoult D.	Clin Diagn Lab Immunol	10.1128/cdli.8.4.847-849.2001	2001
Enzymology	Molecular characterization of the sucB gene encoding the immunogenic dihydrolipoamide succinyltransferase protein of Bartonella vinsonii subsp. berkhoffii and Bartonella quintana.	Gilmore RD, Carpio AM, Kosoy MY, Gage KL.	Infect Immun	10.1128/iai.71.8.4818-4822.2003	2003
Enzymology	Bartonella clarridgeiae, a newly recognized zoonotic pathogen causing inoculation papules, fever, and lymphadenopathy (cat scratch disease).	Kordick DL, Hilyard EJ, Hadfield TL, Wilson KH, Steigerwalt AG, Brenner DJ, Breitschwerdt EB.	J Clin Microbiol	10.1128/jcm.35.7.1813-1818.1997	1997
Phylogeny	Differentiation of pathogenic Bartonella species by infrequent restriction site PCR.	Handley SA, Regnery RL.	J Clin Microbiol	10.1128/jcm.38.8.3010-3015.2000	2000
	Prevalence of Bartonella henselae and Bartonella clarridgeiae in an urban Indonesian cat population.	Marston EL, Finkel B, Regnery RL, Winoto IL, Graham RR, Wignal S, Simanjuntak G, Olson JG.	Clin Diagn Lab Immunol	10.1128/cdli.6.1.41-44.1999	1999
Enzymology	Bartonella henselae in porpoise blood.	Maggi RG, Harms CA, Hohn AA, Pabst DA, McLellan WA, Walton WJ, Rotstein DS, Breitschwerdt EB.	Emerg Infect Dis	10.3201/eid1112.050969	2005
Enzymology	Gray foxes (Urocyon cinereoargenteus) as a potential reservoir of a Bartonella clarridgeiae-like bacterium and domestic dogs as part of a sentinel system for surveillance of zoonotic arthropod-borne pathogens in northern California.	Henn JB, Gabriel MW, Kasten RW, Brown RN, Theis JH, Foley JE, Chomel BB.	J Clin Microbiol	10.1128/jcm.02539-06	2007
Phylogeny	Use of rpoB gene analysis for detection and identification of Bartonella species.	Renesto P, Gouvernet J, Drancourt M, Roux V, Raoult D.	J Clin Microbiol	10.1128/jcm.39.2.430-437.2001	2001
Phylogeny	Study of genotypes and virB4 secretion gene of Bartonella henselae strains from patients with clinically defined cat scratch disease.	Woestyn S, Olive N, Bigaignon G, Avesani V, Delmee M.	J Clin Microbiol	10.1128/jcm.42.4.1420-1427.2004	2004
	Efficacy of enrofloxacin or doxycycline for treatment of Bartonella henselae or Bartonella clarridgeiae infection in cats.	Kordick DL, Papich MG, Breitschwerdt EB.	Antimicrob Agents Chemother	10.1128/aac.41.11.2448	1997
Phylogeny	Limited diversity among human isolates of Bartonella henselae.	Dillon B, Valenzuela J, Don R, Blanckenberg D, Wigney DI, Malik R, Morris AJ, Robson JM, Iredell J.	J Clin Microbiol	10.1128/jcm.40.12.4691-4699.2002	2002
Enzymology	Coyotes (Canis latrans) as the reservoir for a human pathogenic Bartonella sp.: molecular epidemiology of Bartonella vinsonii subsp. berkhoffii infection in coyotes from central coastal California.	Chang CC, Kasten RW, Chomel BB, Simpson DC, Hew CM, Kordick DL, Heller R, Piemont Y, Breitschwerdt EB	J Clin Microbiol	10.1128/JCM.38.11.4193-4200.2000	2000
Phylogeny	Bartonella vinsonii subsp. berkhoffii subsp. nov., isolated from dogs; Bartonella vinsonii subsp. vinsonii; and emended description of Bartonella vinsonii.	Kordick DL, Swaminathan B, Greene CE, Wilson KH, Whitney AM, O'Connor S, Hollis DG, Matar GM, Steigerwalt AG, Malcolm GB, Hayes PS, Hadfield TL, Breitschwerdt EB, Brenner DJ	Int J Syst Bacteriol	10.1099/00207713-46-3-704	1996

References

#20215	Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 )
#20448	Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 28220
#34222	; Curators of the CIP;
#56921	Culture Collection University of Gothenburg (CCUG) ; Curators of the CCUG; CCUG 45779
#66792	Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) .
#68371	Automatically annotated from API 50CH acid .
#68382	Automatically annotated from API zym .
#69479	João F Matias Rodrigues, Janko Tackmann,Gregor Rot, Thomas SB Schmidt, Lukas Malfertheiner, Mihai Danaila,Marija Dmitrijeva, Daniela Gaio, Nicolas Näpflin and Christian von Mering. University of Zurich.: MicrobeAtlas 1.0 beta .
#123849	Collection of Institut Pasteur ; Curators of the CIP; CIP 104960
#125438	Julia Koblitz, Lorenz Christian Reimer, Rüdiger Pukall, Jörg Overmann: Predicting bacterial phenotypic traits through improved machine learning using high-quality, curated datasets. 2024 ( DOI 10.1101/2024.08.12.607695 )
#125439	Philipp Münch, René Mreches, Martin Binder, Hüseyin Anil Gündüz, Xiao-Yin To, Alice McHardy: deepG: Deep Learning for Genome Sequence Data. R package version 0.3.1 .
#126262	A. Lissin, I. Schober, J. F. Witte, H. Lüken, A. Podstawka, J. Koblitz, B. Bunk, P. Dawyndt, P. Vandamme, P. de Vos, J. Overmann, L. C. Reimer: StrainInfo—the central database for linked microbial strain identifiers. ( DOI 10.1093/database/baaf059 )

Content

About us

Bartonella vinsonii subsp. berkhoffii (DSM 28220, ATCC 51672, CCUG 45779)

Name and taxonomic classification

Morphology

Cell morphology

Colony morphology

Culture and growth conditions

Culture medium

Culture temp

Physiology and metabolism

Oxygen tolerance

Spore formation

Halophily

Metabolite utilization

Metabolite production

Metabolite tests

Enzymes

API zym

API 50CHac

Isolation, sampling and environmental information

Isolation source categories

Isolation

Taxonmaps

Interaction and safety

Risk assessment

Sequence information

Genome sequences

Genome browser: GCA_000518105

16S sequences

Genome-based predictions

Predictions

Literature

Literature

References

BacDive

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