Name: Treponema maltophilum BR
Creator: BacDive
License: http://creativecommons.org/licenses/by-nc/4.0/

Strain identifier

BacDive ID: 23288

Type strain:

Species: Treponema maltophilum

Strain Designation: BR

Culture col. no.: DSM 27366, ATCC 51939, CIP 105146, OMZ 679

Strain history: CIP <- 1997, C. Wyss, Zürich Univ., Switzerland: strain OMZ 679

NCBI tax ID(s): 1125699 (strain), 51160 (species)

SI-ID 43254

ATCC 51939, CIP 105146, DSM 27366

Section

Treponema maltophilum BR is an anaerobe, mesophilic, Gram-negative bacterium that was isolated from human periodontal lesions.

Gram-negative
anaerobe
mesophilic
16S sequence
Bacteria
genome sequence

Information on the name and the taxonomic classification. Name and taxonomic classification

	Last LPSN update	14-12-2023 (DD-MM-YYYY)
	Domain	"Bacteria"
	Phylum	*Spirochaetota*
	Class	*Spirochaetia*
	Order	*Spirochaetales*
	Family	*Treponemataceae*
	Genus	*Treponema*
	Species	**Treponema maltophilum**
	Full Scientific Name (LPSN)	Treponema maltophilum Wyss et al. 1996

Information on morphological and physiological properties Morphology

[Ref.: #69480]	Gram stain	negative Confidence in %99.947

[Ref.: #19045]

Incubation period

2-3 days

Information on culture and growth conditions Culture and growth conditions

[Ref.: #19045]

Culture medium

OMIZ-PAT (DSMZ Medium 1494)

[Ref.: #19045]

Culture medium growth

[Ref.: #19045]

Culture medium link

Medium recipe at MediaDive

[Ref.: #19045]

Culture medium composition

expand / minimize

Name: . OMIZ-PAT Medium (modified) (DSMZ Medium 1494)
Composition:
(NH4)6Mo7O24 x 4 H2O 12.4 g/l
Yeast extract 3.0 g/l
Fe SO4 x 7 H2O 2.78015 g/l
D-Glucose 2.0 g/l
D-Mannose 2.0 g/l
D-Arabinose 2.0 g/l
L-Fucose 2.0 g/l
D-Trehalose 2.0 g/l
D-Sucrose 2.0 g/l
L-Rhamnose 2.0 g/l
NH4Cl 1.6 g/l
Glutathione 1.5366 g/l
Ascorbic acid 1.0 g/l
NaHCO3 1.0 g/l
Ethanol 1.0 g/l
KCl 0.968 g/l
D-Maltose 0.8 g/l
D-glucuronic acid 0.8 g/l
D-Mannitol 0.8 g/l
D-galacturonic acid 0.8 g/l
D-Fructose 0.8 g/l
L-Glutamine 0.68 g/l
L-Histidine 0.62 g/l
NaVO3 0.61 g/l
D 0.56 g/l
Pyruvic acid 0.55 g/l
L-Serine 0.525 g/l
Fumaric acid 0.5 g/l
HCl 0.3646 g/l
L-Cysteine HCl 0.35 g/l
L-Glutamic acid 0.3 g/l
Formic acid 0.3 g/l
ZnSO4 x 7 H2O 0.287 g/l
MgSO4 x 7 H2O 0.25 g/l
DL-carnitine 0.2 g/l
N-Acetylglucosamine 0.2 g/l
Citric acid 0.2 g/l
L-Lysine HCl 0.182 g/l
L-Arginine 0.175 g/l
L-Ornithine HCl 0.17 g/l
L-Phenylalanine 0.165 g/l
CaCl2 x H2O 0.15 g/l
L-Methionine 0.15 g/l
L-Asparagine 0.15 g/l
NaH2PO4 x H2O 0.14 g/l
L-Leucine 0.131 g/l
L-Isoleucine 0.131 g/l
NiSO4 x 6 H2O 0.131 g/l
L-Threonine 0.12 g/l
L-Aspartic acid 0.118 g/l
SnCl2 x 2 H2O 0.118 g/l
L-Valine 0.117 g/l
L-Proline 0.115 g/l
L-Tryptophan 0.102 g/l
Nicotinic acid 0.1 g/l
Folinic acid 0.1 g/l
L-Tyrosine 0.09 g/l
NaOH 0.079994 g/l
Glycine 0.075 g/l
Nicotinamide 0.05 g/l
Folic acid 0.05 g/l
D-(+)-biotin 0.05 g/l
Vitamine B12 0.05 g/l
Choline chloride 0.05 g/l
Myo-inositol 0.05 g/l
L-Alanine 0.045 g/l
Hemin 0.026076 g/l
N-acetylmuramic acid 0.025 g/l
Na2SeO3 0.0173 g/l
MnSO4 x H2O 0.0169 g/l
Riboflavine 0.01 g/l
2-Mercaptoethanesulfonic acid 0.01 g/l
Phenol red 0.01 g/l
Putrescine 2 HCl 0.005 g/l
Pyridoxal hydrochloride 0.005 g/l
Pyridoxal phosphate 0.005 g/l
Calcium D-(+)-pantothenate 0.005 g/l
Thiamine HCl 0.005 g/l
Thiamin pyrophosphate 0.005 g/l
Thymidine 0.0024 g/l
N-(2-acetamido)-2-aminoethanesulfonic acid 0.0018 g/l
Hypoxanthine 0.0014 g/l
Uracil 0.0011 g/l
Flavin adenine dinucleotide 0.001 g/l
ß-nicotinamide adenine dinucleotide 0.001 g/l
Coenzym A 0.001 g/l
CuSO4 0.000789 g/l
Cholesterol
Asialofetuin
2-Mercaptoethanol
Isovaleric acid
Valeric acid
2-Methylbutyric acid
Isobutyric acid
DL-alpha-lipoic acid
Rabbit serum
Distilled water

[Ref.: #37205]

Culture medium

MEDIUM 155 - for Treponema maltophilum

[Ref.: #37205]

Culture medium growth

[Ref.: #37205]

Culture medium composition

expand / minimize

[Ref.: #120773]

Culture medium

CIP Medium 155

[Ref.: #120773]

Culture medium growth

[Ref.: #120773]

Culture medium link

Medium recipe provided by DSMZ

	Temperatures	Kind of temperature		Temperature
[Ref.: #19045]			growth	37 °C
[Ref.: #37205]			growth	37 °C

[Ref.: #19045]	Temperature range	mesophilic
[Ref.: #37205]	Temperature range	mesophilic

Information on physiology and metabolism Physiology and metabolism

[Ref.: #19045]	Oxygen tolerance	anaerobe
[Ref.: #69480]	Oxygen tolerance	anaerobe Confidence in %99.211

[Ref.: #69481]	Ability of spore formation	no Confidence in %100
[Ref.: #69480]	Ability of spore formation	no Confidence in %99.996

	Pathway	Enzyme coverage	Annotated reactions
	Pathway annotation	Computationally determined by
[Ref.: #66794]	ethanol fermentation	100	2 of 2
[Ref.: #66794]	adipate degradation	100	2 of 2
[Ref.: #66794]	palmitate biosynthesis	100	22 of 22
[Ref.: #66794]	lipoate biosynthesis	100	5 of 5
[Ref.: #66794]	cis-vaccenate biosynthesis	100	2 of 2
[Ref.: #66794]	L-lactaldehyde degradation	100	3 of 3
[Ref.: #66794]	ribulose monophosphate pathway	100	2 of 2
[Ref.: #66794]	teichoic acid biosynthesis	100	1 of 1
[Ref.: #66794]	CDP-diacylglycerol biosynthesis	100	2 of 2
[Ref.: #66794]	UDP-GlcNAc biosynthesis	100	3 of 3
[Ref.: #66794]	dolichol and dolichyl phosphate biosynthesis	100	2 of 2
[Ref.: #66794]	lactate fermentation	100	4 of 4
[Ref.: #66794]	anapleurotic synthesis of oxalacetate	100	1 of 1
[Ref.: #66794]	suberin monomers biosynthesis	100	2 of 2
[Ref.: #66794]	ceramide biosynthesis	100	1 of 1
[Ref.: #66794]	folate polyglutamylation	100	1 of 1
[Ref.: #66794]	threonine metabolism	90	9 of 10
[Ref.: #66794]	starch degradation	90	9 of 10
[Ref.: #66794]	aspartate and asparagine metabolism	88.89	8 of 9
[Ref.: #66794]	valine metabolism	88.89	8 of 9
[Ref.: #66794]	chorismate metabolism	88.89	8 of 9
[Ref.: #66794]	glycolysis	88.24	15 of 17
[Ref.: #66794]	degradation of sugar alcohols	81.25	13 of 16
[Ref.: #66794]	peptidoglycan biosynthesis	80	12 of 15
[Ref.: #66794]	cellulose degradation	80	4 of 5
[Ref.: #66794]	glycogen metabolism	80	4 of 5
[Ref.: #66794]	photosynthesis	78.57	11 of 14
[Ref.: #66794]	phenylalanine metabolism	76.92	10 of 13
[Ref.: #66794]	glycogen biosynthesis	75	3 of 4
[Ref.: #66794]	ppGpp biosynthesis	75	3 of 4
[Ref.: #66794]	C4 and CAM-carbon fixation	75	6 of 8
[Ref.: #66794]	gluconeogenesis	75	6 of 8
[Ref.: #66794]	cardiolipin biosynthesis	71.43	5 of 7
[Ref.: #66794]	propanol degradation	71.43	5 of 7
[Ref.: #66794]	methane metabolism	66.67	2 of 3
[Ref.: #66794]	formaldehyde oxidation	66.67	2 of 3
[Ref.: #66794]	acetoin degradation	66.67	2 of 3
[Ref.: #66794]	degradation of hexoses	66.67	12 of 18
[Ref.: #66794]	serine metabolism	66.67	6 of 9
[Ref.: #66794]	octane oxidation	66.67	2 of 3
[Ref.: #66794]	NAD metabolism	66.67	12 of 18
[Ref.: #66794]	CO2 fixation in Crenarchaeota	66.67	6 of 9
[Ref.: #66794]	d-mannose degradation	66.67	6 of 9
[Ref.: #66794]	purine metabolism	65.96	62 of 94
[Ref.: #66794]	degradation of pentoses	64.29	18 of 28
[Ref.: #66794]	isoleucine metabolism	62.5	5 of 8
[Ref.: #66794]	pyrimidine metabolism	62.22	28 of 45
[Ref.: #66794]	leucine metabolism	61.54	8 of 13
[Ref.: #66794]	glutamate and glutamine metabolism	60.71	17 of 28
[Ref.: #66794]	Entner Doudoroff pathway	60	6 of 10
[Ref.: #66794]	myo-inositol biosynthesis	60	6 of 10
[Ref.: #66794]	propionate fermentation	60	6 of 10
[Ref.: #66794]	glycine betaine biosynthesis	60	3 of 5
[Ref.: #66794]	methylglyoxal degradation	60	3 of 5
[Ref.: #66794]	methionine metabolism	57.69	15 of 26
[Ref.: #66794]	oxidative phosphorylation	57.14	52 of 91
[Ref.: #66794]	reductive acetyl coenzyme A pathway	57.14	4 of 7
[Ref.: #66794]	non-pathway related	55.26	21 of 38
[Ref.: #66794]	vitamin B6 metabolism	54.55	6 of 11
[Ref.: #66794]	proline metabolism	54.55	6 of 11
[Ref.: #66794]	pentose phosphate pathway	54.55	6 of 11
[Ref.: #66794]	vitamin B1 metabolism	53.85	7 of 13
[Ref.: #66794]	alanine metabolism	51.72	15 of 29
[Ref.: #66794]	citric acid cycle	50	7 of 14
[Ref.: #66794]	toluene degradation	50	2 of 4
[Ref.: #66794]	acetate fermentation	50	2 of 4
[Ref.: #66794]	kanosamine biosynthesis II	50	1 of 2
[Ref.: #66794]	6-hydroxymethyl-dihydropterin diphosphate biosynthesis	50	4 of 8
[Ref.: #66794]	CMP-KDO biosynthesis	50	2 of 4
[Ref.: #66794]	phenylmercury acetate degradation	50	1 of 2
[Ref.: #66794]	glycolate and glyoxylate degradation	50	3 of 6
[Ref.: #66794]	isoprenoid biosynthesis	50	13 of 26
[Ref.: #66794]	cysteine metabolism	50	9 of 18
[Ref.: #66794]	ketogluconate metabolism	50	4 of 8
[Ref.: #66794]	coenzyme A metabolism	50	2 of 4
[Ref.: #66794]	butanoate fermentation	50	2 of 4
[Ref.: #66794]	histidine metabolism	48.28	14 of 29
[Ref.: #66794]	tryptophan metabolism	44.74	17 of 38
[Ref.: #66794]	ubiquinone biosynthesis	42.86	3 of 7
[Ref.: #66794]	lipid metabolism	41.94	13 of 31
[Ref.: #66794]	lysine metabolism	40.48	17 of 42
[Ref.: #66794]	metabolism of amino sugars and derivatives	40	2 of 5
[Ref.: #66794]	arachidonate biosynthesis	40	2 of 5
[Ref.: #66794]	glycine metabolism	40	4 of 10
[Ref.: #66794]	bacilysin biosynthesis	40	2 of 5
[Ref.: #66794]	dTDPLrhamnose biosynthesis	37.5	3 of 8
[Ref.: #66794]	metabolism of disaccharids	36.36	4 of 11
[Ref.: #66794]	tyrosine metabolism	35.71	5 of 14
[Ref.: #66794]	tetrahydrofolate metabolism	35.71	5 of 14
[Ref.: #66794]	IAA biosynthesis	33.33	1 of 3
[Ref.: #66794]	acetyl CoA biosynthesis	33.33	1 of 3
[Ref.: #66794]	selenocysteine biosynthesis	33.33	2 of 6
[Ref.: #66794]	degradation of aromatic, nitrogen containing compounds	33.33	4 of 12
[Ref.: #66794]	sphingosine metabolism	33.33	2 of 6
[Ref.: #66794]	molybdenum cofactor biosynthesis	33.33	3 of 9
[Ref.: #66794]	cyanate degradation	33.33	1 of 3
[Ref.: #66794]	arginine metabolism	33.33	8 of 24
[Ref.: #66794]	1,4-dihydroxy-6-naphthoate biosynthesis	33.33	2 of 6
[Ref.: #66794]	nitrate assimilation	33.33	3 of 9
[Ref.: #66794]	lipid A biosynthesis	33.33	3 of 9
[Ref.: #66794]	degradation of sugar acids	32	8 of 25
[Ref.: #66794]	ascorbate metabolism	31.82	7 of 22
[Ref.: #66794]	urea cycle	30.77	4 of 13
[Ref.: #66794]	coenzyme M biosynthesis	30	3 of 10
[Ref.: #66794]	benzoyl-CoA degradation	28.57	2 of 7
[Ref.: #66794]	flavin biosynthesis	26.67	4 of 15
[Ref.: #66794]	androgen and estrogen metabolism	25	4 of 16
[Ref.: #66794]	carnitine metabolism	25	2 of 8
[Ref.: #66794]	cyclohexanol degradation	25	1 of 4
[Ref.: #66794]	phenylpropanoid biosynthesis	23.08	3 of 13
[Ref.: #66794]	sulfate reduction	23.08	3 of 13
[Ref.: #66794]	4-hydroxymandelate degradation	22.22	2 of 9
[Ref.: #66794]	glutathione metabolism	21.43	3 of 14
		Only first 10 entries are displayed. Click here to see all.

Information on isolation source, the sampling and environmental conditions Isolation, sampling and environmental information

[Ref.: #19045]	Sample type/isolated from	human periodontal lesions
[Ref.: #19045]	Country	Switzerland
[Ref.: #19045]	Country ISO 3 Code	CHE
[Ref.: #19045]	Continent	Europe

[Ref.: #120773]	Sample type/isolated from	Subgingival plaque
[Ref.: #120773]	Country	Switzerland
[Ref.: #120773]	Country ISO 3 Code	CHE
[Ref.: #120773]	Continent	Europe
[Ref.: #120773]	Isolation date	1992
* marker position based on {}

Isolation sources categories

#Host	#Human	-
#Host Body-Site	#Oral cavity and airways	#Mouth
#Host Body-Site	#Other	#Wound

What are isolation sources categories?

[Ref.: #69479]

Global distribution of 16S sequence X87140 (>99% sequence identity) for Treponema maltophilum subclade from Microbeatlas

Aquatic Samples	60
Soil Samples	32
Animal Samples	2778
Plant Samples	19
Total Samples	2889

Information on possible application of the strain and its possible interaction with e.g. potential hosts Safety information

[Ref.: #19045]	Biosafety level	2	Risk group (German classification) According to TRBA 466
[Ref.: #120773]	Biosafety level	2	Risk group (French classification)

Information on genomic background e.g. entries in nucleic sequence databass Sequence information

16S Sequence information:

	Sequence accession description	Seq. accession number	Sequence length (bp)	Sequence database	Associated NCBI tax ID
[Ref.: #19045]	Treponema maltophilum 16S rRNA gene (patient BR)	X87140	1497	ENA	51160 tax ID

Genome sequence information:

	Sequence accession description	Seq. accession number	Assembly level	Sequence database	Associated NCBI tax ID
[Ref.: #66792]	Treponema maltophilum ATCC 51939	GCA_000413055	scaffold	GenBank	1125699 tax ID	*
[Ref.: #66792]	Treponema maltophilum ATCC 51939	1125699.3	wgs	PATRIC	1125699 tax ID	*
[Ref.: #66792]	Treponema maltophilum ATCC 51939	2541046974	draft	JGI IMG/M	1125699 tax ID	*

Data predicted using genome information as a basis Genome-based predictions

	Trait	Prediction	Confidence in %	In training data
	Predictions from GenomeNet Sporulation v. 1 based on: Treponema maltophilum ATCC 51939 ATCC 51939 NCBI: GCA_000413055.1
[Ref.: #69481]	spore-forming	no	100	no

	Trait	Prediction	Confidence in %	In training data
	Predictions from Diaspora project based on: Treponema maltophilum ATCC 51939 ATCC 51939 NCBI: GCA_000413055.1
[Ref.: #69480]	motile	yes	80.57	no
[Ref.: #69480]	flagellated	no	84.672	no
[Ref.: #69480]	gram-positive	no	95.142	no
[Ref.: #69480]	anaerobic	yes	99.332	yes
[Ref.: #69480]	aerobic	no	98.889	no
[Ref.: #69480]	halophile	no	78.196	no
[Ref.: #69480]	spore-forming	no	91.569	no
[Ref.: #69480]	thermophile	no	93.046	yes
[Ref.: #69480]	glucose-util	yes	76.115	no
[Ref.: #69480]	glucose-ferment	yes	75.912	no

Availability in culture collections External links

[Ref.: #19045]

Culture collection no.

DSM 27366, ATCC 51939, CIP 105146, OMZ 679

[Ref.: #87509]

SI-ID 43254

Literature:

Topic	Title	Authors	Journal	DOI	Year
Metabolism	A flagellar gene cluster from the oral spirochaete Treponema maltophilum.	Heuner K, Grosse K, Schade R, Gobel UB	Microbiology (Reading)	10.1099/00221287-146-2-497	2000	*
Enzymology	Cloning and characterization of a gene (mspA) encoding the major sheath protein of Treponema maltophilum ATCC 51939(T).	Heuner K, Choi BK, Schade R, Moter A, Otto A, Gobel UB	J Bacteriol	10.1128/JB.181.3.1025-1029.1999	1999	*

References

#19045

Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 27366

#20215

Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 )

#37205 ; Curators of the CIP;

#66792

Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) .

#66794

Antje Chang, Lisa Jeske, Sandra Ulbrich, Julia Hofmann, Julia Koblitz, Ida Schomburg, Meina Neumann-Schaal, Dieter Jahn, Dietmar Schomburg: BRENDA, the ELIXIR core data resource in 2021: new developments and updates. Nucleic Acids Res. 49: D498 - D508 2020 ( DOI 10.1093/nar/gkaa1025 , PubMed 33211880 )

#69479

João F Matias Rodrigues, Janko Tackmann,Gregor Rot, Thomas SB Schmidt, Lukas Malfertheiner, Mihai Danaila,Marija Dmitrijeva, Daniela Gaio, Nicolas Näpflin and Christian von Mering. University of Zurich.: MicrobeAtlas 1.0 beta .

#69480

Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Predictions based on genome sequence made in the Diaspora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) .

#69481

Xiao-Yin To, René Mreches, Martin Binder, Alice C. McHardy, Philipp C. Münch: Predictions based on the model GenomeNet Sporulation v. 1 . ( DOI 10.21203/rs.3.rs-2527258/v1 )

#87509

Reimer, L.C., Lissin, A.,Schober, I., Witte,J.F., Podstawka, A., Lüken, H., Bunk, B.,Overmann, J.: StrainInfo: A central database for resolving microbial strain identifiers . ( DOI 10.60712/SI-ID43254.1 )

#120773 Collection of Institut Pasteur ; Curators of the CIP; CIP 105146
* These data were automatically processed and therefore are not curated

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Treponema maltophilum ATCC 51939 ATCC 51939

Treponema maltophilum ATCC 51939 ATCC 51939

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