Strain identifier

BacDive ID: 22963

Type strain: No

Species: Clostridioides difficile

Strain Designation: R20291

Culture col. no.: DSM 27147, NCTC 13366

Strain history: <- P. Bracegirdle, Health Protection Agency Culture Collections, Salisbury, United Kingdom; NCTC 13366

NCBI tax ID(s): 1496 (species)

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Clostridioides difficile R20291 is an anaerobe, spore-forming, mesophilic human pathogen that was isolated from Faeces from a symptomatic patient. Outbreak at Stoke Mandeville Hospital, UK.

  1. rod-shaped
  2. spore-forming
  3. anaerobe
  4. human pathogen
  5. mesophilic
  6. Bacteria
  7. genome sequence
  • Availability in culture collections External linksarrow_down
  • [Ref.: #18803] Culture collection no. DSM 27147, NCTC 13366
    [Ref.: #87210] *
    Literature: Only first 10 entries are displayed. Click here to see all.Click here to see only first 10 entries.
    Topicarrow to sort Titlearrow to sort Authorsarrow to sort Journalarrow to sort DOIarrow to sort Yeararrow to sort
    Pathogenicity Genomic and Phenotypic Characterization of the Nontoxigenic Clostridioides difficile Strain CCUG37785 and Demonstration of Its Therapeutic Potential for the Prevention of C. difficile Infection. Wang S, Heuler J, Wickramage I, Sun X Microbiol Spectr 10.1128/spectrum.01788-21 2022 *
    Metabolism Flagellum and toxin phase variation impacts intestinal colonization and disease development in a mouse model of Clostridioides difficile infection. Trzilova D, Warren MAH, Gadda NC, Williams CL, Tamayo R Gut Microbes 10.1080/19490976.2022.2038854 2022 *
    Pathogenicity Glucosyltransferase-dependent and independent effects of Clostridioides difficile toxins during infection. Peritore-Galve FC, Shupe JA, Cave RJ, Childress KO, Washington MK, Kuehne SA, Lacy DB PLoS Pathog 10.1371/journal.ppat.1010323 2022 *
    Metabolism Oxidative ornithine metabolism supports non-inflammatory C. difficile colonization. Pruss KM, Enam F, Battaglioli E, DeFeo M, Diaz OR, Higginbottom SK, Fischer CR, Hryckowian AJ, Van Treuren W, Dodd D, Kashyap P, Sonnenburg JL Nat Metab 10.1038/s42255-021-00506-4 2022 *
    Metabolism c-di-GMP Inhibits Early Sporulation in Clostridioides difficile. Edwards AN, Willams CL, Pareek N, McBride SM, Tamayo R mSphere 10.1128/msphere.00919-21 2021 *
    Pathogenicity Studies on the Importance of the 7alpha-, and 12alpha- hydroxyl groups of N-Aryl-3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-amides on their Antigermination Activity Against a Hypervirulent Strain of Clostridioides (Clostridium) difficile. Sharma SK, Yip C, Simon MP, Phan J, Abel-Santos E, Firestine SM Bioorg Med Chem 10.1016/j.bmc.2021.116503 2021 *
    Physiology Impact of Phage CDHS-1 on the Transcription, Physiology and Pathogenicity of a Clostridioides difficile Ribotype 027 Strain, R20291. Nale JY, Al-Tayawi TS, Heaphy S, Clokie MRJ Viruses 10.3390/v13112262 2021 *
    Physiology FliW and CsrA Govern Flagellin (FliC) Synthesis and Play Pleiotropic Roles in Virulence and Physiology of Clostridioides difficile R20291. Zhu D, Wang S, Sun X Front Microbiol 10.3389/fmicb.2021.735616 2021 *
    Pathogenicity Biofilm regulation in Clostridioides difficile: Novel systems linked to hypervirulence. Taggart MG, Snelling WJ, Naughton PJ, La Ragione RM, Dooley JSG, Ternan NG PLoS Pathog 10.1371/journal.ppat.1009817 2021 *
    Metabolism Ebselen Not Only Inhibits Clostridioides difficile Toxins but Displays Redox-Associated Cellular Killing. Marreddy RKR, Olaitan AO, May JN, Dong M, Hurdle JG Microbiol Spectr 10.1128/Spectrum.00448-21 2021 *

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