Burkholderia multivorans (DSM 13243, CIP 105495, LMG 13010)

Name: Burkholderia multivorans (DSM 13243, CIP 105495, LMG 13010)
Creator: BacDive
License: http://creativecommons.org/licenses/by/4.0/

BacDive ID 1941

Type strain

Strain Designation Cepa 002

Culture col. no. DSM 13243 CIP 105495 LMG 13010 NCTC 13007 CCUG 34080 2 more

NCBI tax ID(s) 985079 87883

Special Collections DSMZ CCUG CIP

History <- S. Lauwers (Pseudomonas cepacia) <- M. Struelens CIP <- 1998, LMG <- S. Lauwers <- M. Struelens

Links

Burkholderia multivorans Cepa 002 is an aerobe, Gram-negative, motile bacterium that was isolated from patient suffering from cystic fibrosis.

Gram-negative motile rod-shaped aerobe genome sequence 16S sequence Bacteria

Name and taxonomic classification

SI-ID 7297

LMG 13010,CIP 105495,NCTC 13007,ATCC BAA-247,CCUG 34080,DSM 13243,KCTC 2970,CCM 4863,BCRC 17447,CCRC 17447,VTT E-022186,NCPPB 4254

@ref 20215

Last LPSN update 2026-02-09 11:18:13

Domain Bacteria

Phylum Pseudomonadota

Class Betaproteobacteria

Order Burkholderiales

Family Burkholderiaceae

Genus Burkholderia

Species Burkholderia multivorans

Full scientific name Burkholderia multivorans Vandamme et al. 1997

BacDive ID	Other strains from **Burkholderia multivorans** (59)	Type strain
143845	B. multivorans CCUG 21496
147066	B. multivorans CCUG 32783
147752	B. multivorans CCUG 34167, LMG 14293
147874	B. multivorans CCUG 34415, LMG 16229
147895	B. multivorans CCUG 34449, LMG 16231
148354	B. multivorans CCUG 35274
148425	B. multivorans CCUG 35415
148766	B. multivorans CCUG 35916
148800	B. multivorans CCUG 35953
148896	B. multivorans CCUG 36562 B, LMG R-923
149163	B. multivorans CCUG 36978, LMG R1050
149188	B. multivorans CCUG 37240, LMG 16665
149189	B. multivorans CCUG 37242, LMG 16775
149190	B. multivorans CCUG 37243, LMG 17567
149191	B. multivorans CCUG 37244, LMG 17568
149192	B. multivorans CCUG 37245, ATCC 17616, LMG 17588
149903	B. multivorans CCUG 38651
150291	B. multivorans CCUG 39522
150446	B. multivorans CCUG 39953
150532	B. multivorans CCUG 41506
150716	B. multivorans CCUG 42036
150887	B. multivorans CCUG 42629
151040	B. multivorans CCUG 43127
151232	B. multivorans CCUG 43517
151265	B. multivorans CCUG 43584
151314	B. multivorans CCUG 43728
151774	B. multivorans CCUG 44838
151942	B. multivorans CCUG 45292
152017	B. multivorans CCUG 45557
152182	B. multivorans CCUG 45989
152236	B. multivorans CCUG 46187
152308	B. multivorans CCUG 46394
152396	B. multivorans CCUG 46669
152488	B. multivorans CCUG 46920
152547	B. multivorans CCUG 47036
152560	B. multivorans CCUG 47053
152629	B. multivorans CCUG 47232
152957	B. multivorans CCUG 48126
153398	B. multivorans CCUG 49473
153719	B. multivorans CCUG 50736
153953	B. multivorans CCUG 51751
154030	B. multivorans CCUG 52053
154337	B. multivorans CCUG 53168
154402	B. multivorans CCUG 53408
154741	B. multivorans CCUG 55067
154909	B. multivorans CCUG 55646
154910	B. multivorans CCUG 55647
155261	B. multivorans CCUG 57130
155343	B. multivorans CCUG 57397
155412	B. multivorans CCUG 57653
155727	B. multivorans CCUG 59151
156052	B. multivorans CCUG 60225
156055	B. multivorans CCUG 60232
156195	B. multivorans CCUG 60686
156278	B. multivorans CCUG 61010
156349	B. multivorans CCUG 61252
156391	B. multivorans CCUG 61527
156422	B. multivorans CCUG 61674
175055	B. multivorans 114287, DSM 114287

Morphology

Cell morphology

@ref	Gram stain	Cell shape	Confidence
121175	negative	rod-shaped
125438	negative		97.5
125439	negative		91.4

Colony morphology

@ref	Type of hemolysis	Incubation period
4980	gamma	1-2 days

Pigmentation

@ref	Production	Name
121175		Pyocyanin

Culture and growth conditions

Culture medium

@ref	Name	Medium link	Composition
4980	NUTRIENT AGAR (DSMZ Medium 1)	Medium recipe at MediaDive	Name: NUTRIENT AGAR (DSMZ Medium 1) Composition: Agar 15.0 g/l Peptone 5.0 g/l Meat extract 3.0 g/l Distilled water
35830	MEDIUM 72- for trypto casein soja agar		Distilled water make up to (1000.000 ml);Trypto casein soy agar (40.000 g)
4980	TRYPTICASE SOY YEAST EXTRACT MEDIUM (DSMZ Medium 92)	Medium recipe at MediaDive	Name: TRYPTICASE SOY YEAST EXTRACT MEDIUM (DSMZ Medium 92) Composition: Trypticase soy broth 30.0 g/l Agar 15.0 g/l Yeast extract 3.0 g/l Distilled water
4980	COLUMBIA BLOOD MEDIUM (DSMZ Medium 693)	Medium recipe at MediaDive	Name: COLUMBIA BLOOD MEDIUM (DSMZ Medium 693) Composition: Defibrinated sheep blood 50.0 g/l Columbia agar base
121175	CIP Medium 72	Medium recipe at CIP

Culture temp

@ref	Growth	Type	Temperature (°C)
4980	positive	growth	28
4980	positive	growth	30
35830	positive	growth	30
51924	positive	growth	37
121175	positive	growth	25-41
121175	negative	growth	5
121175	negative	growth	10

Physiology and metabolism

Oxygen tolerance

@ref	Oxygen tolerance	Confidence
51924	aerobe
121175	obligate aerobe
125438	aerobe	93.137
125439	aerobe	98.5

Spore formation

@ref	Spore formation	Confidence
125439		91

Halophily

@ref	Salt	Growth	Tested relation	Concentration
121175	NaCl	positive	growth	0-6 %
121175	NaCl		growth	8 %
121175	NaCl		growth	10 %

Metabolite utilization

@ref	Chebi-ID	Metabolite	Utilization activity	Kind of utilization tested
68369	17128 ChEBI	adipate	+	assimilation	from API 20NE
68369	29016 ChEBI	arginine	-	hydrolysis	from API 20NE
121175	16947 ChEBI	citrate	+	carbon source
68369	17634 ChEBI	D-glucose	+	assimilation	from API 20NE
68369	17634 ChEBI	D-glucose	-	fermentation	from API 20NE
68369	16899 ChEBI	D-mannitol	+	assimilation	from API 20NE
68369	16024 ChEBI	D-mannose	+	assimilation	from API 20NE
68369	27689 ChEBI	decanoate	+	assimilation	from API 20NE
121175	4853 ChEBI	esculin	-	hydrolysis
68369	5291 ChEBI	gelatin	-	hydrolysis	from API 20NE
68369	24265 ChEBI	gluconate	+	assimilation	from API 20NE
68369	30849 ChEBI	L-arabinose	+	assimilation	from API 20NE
68369	25115 ChEBI	malate	+	assimilation	from API 20NE
68369	17306 ChEBI	maltose	-	assimilation	from API 20NE
68369	59640 ChEBI	N-acetylglucosamine	+	assimilation	from API 20NE
121175	17632 ChEBI	nitrate	+	reduction
121175	17632 ChEBI	nitrate	-	respiration
121175	16301 ChEBI	nitrite	-	reduction
68369	27897 ChEBI	tryptophan	-	energy source	from API 20NE
68369	16199 ChEBI	urea	-	hydrolysis	from API 20NE

Antibiotic resistance

@ref	Metabolite	Is sensitive	Is resistant
121175	0129 (2,4-Diamino-6,7-di-iso-propylpteridine phosphate)

Metabolite production

@ref	Chebi-ID	Metabolite	Production
68369	35581 ChEBI	indole		from API 20NE
121175	35581 ChEBI	indole

Metabolite tests

@ref	Chebi-ID	Metabolite	Indole test
68369	35581 ChEBI	indole	-	from API 20NE

Enzymes

@ref	Value	Activity	Ec
68382	acid phosphatase	+	3.1.3.2	from API zym
121175	alcohol dehydrogenase	-	1.1.1.1
68382	alkaline phosphatase	+	3.1.3.1	from API zym
68382	alpha-chymotrypsin	-	3.4.21.1	from API zym
68382	alpha-fucosidase	-	3.2.1.51	from API zym
68382	alpha-galactosidase	-	3.2.1.22	from API zym
68382	alpha-glucosidase	-	3.2.1.20	from API zym
68382	alpha-mannosidase	-	3.2.1.24	from API zym
121175	amylase	-
68369	arginine dihydrolase	-	3.5.3.6	from API 20NE
121175	beta-galactosidase	+	3.2.1.23
68382	beta-galactosidase	-	3.2.1.23	from API zym
68382	beta-glucosidase	+	3.2.1.21	from API zym
68382	beta-glucuronidase	-	3.2.1.31	from API zym
121175	caseinase	-	3.4.21.50
4980	catalase	+	1.11.1.6
121175	catalase	+	1.11.1.6
68382	cystine arylamidase	-	3.4.11.3	from API zym
68369	cytochrome oxidase	+	1.9.3.1	from API 20NE
4980	cytochrome-c oxidase	+	1.9.3.1
121175	DNase	-
68382	esterase (C 4)	+		from API zym
68382	esterase lipase (C 8)	+		from API zym
121175	gelatinase	-
68369	gelatinase	-		from API 20NE
121175	lecithinase	+
68382	leucine arylamidase	+	3.4.11.1	from API zym
121175	lipase	-
68382	lipase (C 14)	+		from API zym
121175	lysine decarboxylase	-	4.1.1.18
68382	N-acetyl-beta-glucosaminidase	-	3.2.1.52	from API zym
68382	naphthol-AS-BI-phosphohydrolase	+		from API zym
121175	ornithine decarboxylase	-	4.1.1.17
121175	oxidase	+
68382	trypsin	-	3.4.21.4	from API zym
121175	tryptophan deaminase	-
121175	tween esterase	+
121175	urease	+	3.5.1.5
68369	urease	-	3.5.1.5	from API 20NE
68382	valine arylamidase	-		from API zym

API zym

@ref	Control	Alkaline phosphatase	Esterase (C 4)	2-naphtyl caprylateEsterase Lipase (C 8)	Lipase (C 14)	L-leucyl-2-naphthylamideLeucine arylamidase	L-valyl-2-naphthylamideValine arylamidase	L-cystyl-2-naphthylamideCystine arylamidase	Trypsin	alpha- Chymotrypsin	Acid phosphatase	Naphthol-AS-BI-phosphateNaphthol-AS-BI-phosphohydrolase	alpha- Galactosidase	beta- Galactosidase	beta- Glucuronidase	alpha- Glucosidase	beta- Glucosidase	N-acetyl-beta- glucosaminidase	alpha- Mannosidase	alpha- Fucosidase
121175	-	+	+	+	+	+	-	-	-	-	+	+	-	-	-	-	+	-	-	-

API 20NE

@ref	Reduction of nitratesNO3	TRP	GLU_ Ferm	ADH (Arg)	URE	ESC	GEL	PNPG	GLU_ Assim	ARA	MNE	MAN	NAG	MAL	GNT	CAP	ADI	MLT	CIT	PAC	OX
4980	+	-	-	-	-	-	-	+	+	+	+	+	+	-	+	+	+	+	+	+	+
4980	+	-	-	-	-	+/-	-	+	+	+	+	+	+	-	+	+	+	+	+	+	+
4980	-	-	-	-	-	-	-	+	+	+	+	+	+	-	+	+	+	+	+	+	+

API biotype100

@ref	ControlQ	D-glucose as carbon sourceGLU	D-fructose as carbon sourceFRU	D-galactose as carbon sourceGAL	D-trehalose as carbon sourceTRE	D-mannose as carbon sourceMNE	L-sorbose as carbon sourceSBE	D-melibiose as carbon sourceMEL	sucrose as carbon sourceSAC	D-raffinose as carbon sourceRAF	maltotriose as carbon sourceMTE	maltose as carbon sourceMAL	lactose as carbon sourceLAC	lactulose as carbon sourceLTE	1-O-methyl-beta-galactopyranoside as carbon sourceMbGa	1-O-methyl-alpha-galactopyranoside as carbon sourceMaGa	D-cellobiose as carbon sourceCEL	gentiobiose as carbon sourceGEN	1-O-methyl-beta-D-glucopyranoside as carbon sourceMbGu	esculin as carbon sourceESC	D-ribose as carbon sourceRIB	L-arabinose as carbon sourceARA	D-xylose as carbon sourceXYL	palatinose as carbon sourcePLE	L-rhamnose as carbon sourceRHA	L-fucose as carbon sourceFUC	D-melezitose as carbon sourceMLZ	D-arabitol as carbon sourceDARL	L-arabitol as carbon sourceLARL	xylitol as carbon sourceXLT	dulcitol as carbon sourceDUL	D-tagatose as carbon sourceTAG	glycerol as carbon sourceGLY	myo-inositol as carbon sourceINO	D-mannitol as carbon sourceMAN	maltitol as carbon sourceMTL	D-turanose as carbon sourceTUR	D-sorbitol as carbon sourceSOR	adonitol as carbon sourceADO	hydroxyquinoline-beta-glucuronide as carbon sourceHBG	D-lyxose as carbon sourceLYX	i-erythritol as carbon sourceERY	1-O-methyl-alpha-D-glucoside as carbon sourceMDG	3-O-methyl-D-glucose as carbon source3MDG	D-saccharate as carbon sourceSAT	mucate as carbon sourceMUC	L-tartrate as carbon sourceLTAT	D-tartrate as carbon sourceDTAT	meso-tartrate as carbon sourceMTAT	D-malate as carbon sourceDMLT	L-malate as carbon sourceLMLT	cis-aconitate as carbon sourceCATE	trans-aconitate as carbon sourceTATE	tricarballylate as carbon sourceTTE	citrate as carbon sourceCIT	D-glucuronate as carbon sourceGRT	D-galacturonate as carbon sourceGAT	2-ketogluconate as carbon source2KG	5-ketogluconate as carbon source5KG	tryptophan as carbon sourceTRY	N-acetyl-D-glucosamine as carbon sourceNAG	D-gluconate as carbon sourceGNT	phenylacetate as carbon sourcePAC	protocatechuate as carbon sourcePAT	4-hydroxybenzoate as carbon sourcepOBE	quinate as carbon sourceQAT	gentisate as carbon sourceGTE	3-hydroxybenzoate as carbon sourcemOBE	benzoate as carbon sourceBAT	3-phenylpropionate as carbon sourcePPAT	m-coumarate as carbon sourceCMT	trigonelline as carbon sourceTGE	betaine as carbon sourceBET	putrescine as carbon sourcePCE	4-aminobutyrate as carbon sourceABT	histamine as carbon sourceHIN	DL-lactate as carbon sourceLAT	caprate as carbon sourceCAP	caprylate as carbon sourceCYT	L-histidine as carbon sourceHIS	succinate as carbon sourceSUC	fumarate as carbon sourceFUM	glutarate as carbon sourceGRE	DL-glycerate as carbon sourceGYT	5-aminovalerate as carbon sourceAVT	ethanolamine as carbon sourceETN	tryptamine as carbon sourceTTN	D-glucosamine as carbon sourceGLN	itaconate as carbon sourceITA	3-hydroxybutyrate as carbon source3OBU	L-aspartate as carbon sourceAPT	L-glutamate as carbon sourceGTT	L-proline as carbon sourcePRO	D-alanine as carbon sourceDALA	L-alanine as carbon sourceLALA	L-serine as carbon sourceSER	malonate as carbon sourceMNT	propionate as carbon sourcePROP	L-tyrosine as carbon sourceTYR	2-ketoglutarate as carbon source2KT
121175	not determinedn.d.	+	+	+	+	+	-	-	-	-	-	-	-	-	+	-	+	+	-	+	+	+	+	-	-	+	-	+	+	+	+	+	+	+	+	-	-	+	+	-	+	-	-	-	+	+	+	-	-	+	+	+	+	+	+	+	+	+	-	+	+	+	+	+	+	+	+	+	+	-	-	+	+	+	+	+	-	+	+	+	+	+	+	+	+	+	+	+	-	+	+	+	+	+	+	+	+	+	+	+

Isolation, sampling and environmental information

Isolation source categories

Cat1	Cat2	Cat3
#Infection	#Disease	#Cystic fibrosis
#Infection	#Patient	-

Isolation

@ref	Sample type	Country	Country ISO 3 Code	Continent	Latitude	Longitude	Sampling date	Geographic location	Isolation date
4980	patient suffering from cystic fibrosis	Belgium	BEL	Europe	50.5011	4.4765 50.5011/4.4765
51924	Human sputum,cystic fibrosis	Belgium	BEL	Europe			1992	Brussels
121175	Cystic fibrosis patient	Belgium	BEL	Europe					1992

Interaction and safety

Risk assessment

@ref	Biosafety level	Biosafety level comment
4980	2	Risk group (German classification) According to TRBA 466
121175	1	Risk group (French classification) According to TRBA 466

Sequence information

Genome sequences

@ref	Description	Assembly level	INSDC accession	BV-BRC accession	IMG accession	NCBI tax ID	Score
66792	51485_A01 assembly for Burkholderia multivorans NCTC13007	contig	GCA_900446205	87883.262	2916581165	87883	76.26

16S sequences

@ref	Description	Accession	Length	NCBI tax ID
20218	Burkholderia multivorans 16S ribosomal RNA gene, partial sequence	AF148555	1344	985079
20218	Burkholderia multivorans 16S rRNA gene, strain LMG 13010T	Y18703	1479	985079
4980	Burkholderia multivorans strain CIP 105495 16S ribosomal RNA gene, partial sequence	EU024178	1313	985079
124043	Burkholderia multivorans ATCC BAA-247 strain LMG 13010 16S ribosomal RNA gene, partial sequence.	HQ849090	1124	985079

Genome-based predictions

Predictions

Predictions from Deep Learning for Genome Sequence Data. R package version 0.3.1 based on: Burkholderia multivorans NCTC13007
NCBI: GCA_900446205

@ref	Trait	Model	Prediction	Confidence in %	In training data
125439	spore_formation	BacteriaNetⓘ	no	91.00	no
125439	motility	BacteriaNetⓘ	yes	71.00	no
125439	gram_stain	BacteriaNetⓘ	negative	91.40	no
125439	oxygen_tolerance	BacteriaNetⓘ	aerobe	98.50	no

Predictions from bacterial phenotypic traits through improved machine learning using high-quality, curated datasets based on: Burkholderia multivorans strain NCTC13007
PATRIC: 87883.262

@ref	Trait	Model	Prediction	Confidence in %	In training data
125438	gram-positive	gram-positiveⓘ	no	97.50	no
125438	anaerobic	anaerobicⓘ	no	97.12	yes
125438	aerobic	aerobicⓘ	yes	93.14	yes
125438	spore-forming	spore-formingⓘ	no	89.74	no
125438	thermophilic	thermophileⓘ	no	97.25	yes
125438	flagellated	motile2+ⓘ	yes	83.08	no

Literature

Topic	Title	Authors	Journal	DOI	Year
Phylogeny	Fluorescence in situ hybridization for rapid identification of Achromobacter xylosoxidans and Alcaligenes faecalis recovered from cystic fibrosis patients.	Wellinghausen N, Wirths B, Poppert S.	J Clin Microbiol	10.1128/jcm.00508-06	2006
	[⁶⁸Ga]Ga-Ornibactin for Burkholderia cepacia complex Infection Imaging Using Positron Emission Tomography.	Bendova K, Raclavsky V, Novotny R, Luptakova D, Popper M, Novy Z, Hajduch M, Petrik M.	J Med Chem	10.1021/acs.jmedchem.3c00469	2023
	A flagella-dependent Burkholderia jumbo phage controls rice seedling rot and steers Burkholderia glumae toward reduced virulence in rice seedlings.	Supina BSI, McCutcheon JG, Peskett SR, Stothard P, Dennis JJ.	mBio	10.1128/mbio.02814-24	2025
	The Isolation and Characterization of a Broad Host Range Bcep22-like Podovirus JC1.	Davis CM, Ruest MK, Cole JH, Dennis JJ.	Viruses	10.3390/v14050938	2022
	Application of qPCR assays based on haloacids transporter gene dehp2 for discrimination of Burkholderia and Paraburkholderia.	Su X, Shi Y, Li R, Lu ZN, Zou X, Wu JX, Han ZG.	BMC Microbiol	10.1186/s12866-019-1411-0	2019
Cultivation	Evaluation of Three Culture Media for Isolation of Burkholderia cepacia Complex from Respiratory Samples of Patients with Cystic Fibrosis.	Marrs ECL, Perry A, Perry JD.	Microorganisms	10.3390/microorganisms9122604	2021
Pathogenicity	Residence in biofilms allows Burkholderia cepacia complex (Bcc) bacteria to evade the antimicrobial activities of neutrophil-like dHL60 cells.	Murphy MP, Caraher E.	Pathog Dis	10.1093/femspd/ftv069	2015
Metabolism	Immunoproteomic analysis of proteins expressed by two related pathogens, Burkholderia multivorans and Burkholderia cenocepacia, during human infection.	Shinoy M, Dennehy R, Coleman L, Carberry S, Schaffer K, Callaghan M, Doyle S, McClean S.	PLoS One	10.1371/journal.pone.0080796	2013
	Effect of beta-Lactamase inhibitors on in vitro activity of beta-Lactam antibiotics against Burkholderia cepacia complex species.	Everaert A, Coenye T.	Antimicrob Resist Infect Control	10.1186/s13756-016-0142-3	2016
Phylogeny	Performance of pyrosequencing versus MALDI-TOF MS in bacteria identification in chronic lung disease.	Navratilova L, Prochazkova P, Bardon J, Novotny R, Zapalka M, Jakubec P, Zatloukal J, Kolek V, Kopriva F, Flodrova P, Raclavsky V.	J Biol Methods	10.14440/jbm.2016.125	2016
Pathogenicity	Pseudomonas aeruginosa-Derived Rhamnolipids and Other Detergents Modulate Colony Morphotype and Motility in the Burkholderia cepacia Complex.	Bernier SP, Hum C, Li X, O'Toole GA, Magarvey NA, Surette MG.	J Bacteriol	10.1128/jb.00171-17	2017
Metabolism	The Role of Reactive Oxygen Species in Antibiotic-Induced Cell Death in Burkholderia cepacia Complex Bacteria.	Van Acker H, Gielis J, Acke M, Cools F, Cos P, Coenye T.	PLoS One	10.1371/journal.pone.0159837	2016
Pathogenicity	Biocide susceptibility of the Burkholderia cepacia complex.	Rose H, Baldwin A, Dowson CG, Mahenthiralingam E.	J Antimicrob Chemother	10.1093/jac/dkn540	2009
Pathogenicity	Elucidation of the mechanism behind the potentiating activity of baicalin against Burkholderia cenocepacia biofilms.	Slachmuylders L, Van Acker H, Brackman G, Sass A, Van Nieuwerburgh F, Coenye T.	PLoS One	10.1371/journal.pone.0190533	2018
Pathogenicity	Antibacterial activity of a lectin-like Burkholderia cenocepacia protein.	Ghequire MG, De Canck E, Wattiau P, Van Winge I, Loris R, Coenye T, De Mot R.	Microbiologyopen	10.1002/mbo3.95	2013
Pathogenicity	Burkholderia is highly resistant to human Beta-defensin 3.	Sahly H, Schubert S, Harder J, Rautenberg P, Ullmann U, Schroder J, Podschun R.	Antimicrob Agents Chemother	10.1128/aac.47.5.1739-1741.2003	2003
Pathogenicity	Quorum sensing inhibitors increase the susceptibility of bacterial biofilms to antibiotics in vitro and in vivo.	Brackman G, Cos P, Maes L, Nelis HJ, Coenye T.	Antimicrob Agents Chemother	10.1128/aac.00045-11	2011
	Diagnostically and experimentally useful panel of strains from the Burkholderia cepacia complex.	Mahenthiralingam E, Coenye T, Chung JW, Speert DP, Govan JR, Taylor P, Vandamme P.	J Clin Microbiol	10.1128/jcm.38.2.910-913.2000	2000
Phylogeny	Biofilm formation and acyl homoserine lactone production in the Burkholderia cepacia complex.	Conway BA, Venu V, Speert DP.	J Bacteriol	10.1128/jb.184.20.5678-5685.2002	2002
	Comparative analysis of plant and animal models for characterization of Burkholderia cepacia virulence.	Bernier SP, Silo-Suh L, Woods DE, Ohman DE, Sokol PA.	Infect Immun	10.1128/iai.71.9.5306-5313.2003	2003
Pathogenicity	Investigating the Role of the Host Multidrug Resistance Associated Protein Transporter Family in Burkholderia cepacia Complex Pathogenicity Using a Caenorhabditis elegans Infection Model.	Tedesco P, Visone M, Parrilli E, Tutino ML, Perrin E, Maida I, Fani R, Ballestriero F, Santos R, Pinilla C, Di Schiavi E, Tegos G, de Pascale D.	PLoS One	10.1371/journal.pone.0142883	2015
Phylogeny	Development of a species-specific fur gene-based method for identification of the Burkholderia cepacia complex.	Lynch KH, Dennis JJ, Dennis JJ.	J Clin Microbiol	10.1128/jcm.01460-07	2008
Pathogenicity	Identification of a novel virulence factor in Burkholderia cenocepacia H111 required for efficient slow killing of Caenorhabditis elegans.	Huber B, Feldmann F, Kothe M, Vandamme P, Wopperer J, Riedel K, Eberl L.	Infect Immun	10.1128/iai.72.12.7220-7230.2004	2004
Metabolism	Iron Acquisition Mechanisms and Their Role in the Virulence of Burkholderia Species.	Butt AT, Thomas MS.	Front Cell Infect Microbiol	10.3389/fcimb.2017.00460	2017
Genetics	Multilocus sequence typing breathes life into a microbial metagenome.	Mahenthiralingam E, Baldwin A, Drevinek P, Vanlaere E, Vandamme P, LiPuma JJ, Dowson CG.	PLoS One	10.1371/journal.pone.0000017	2006
	Symmetrical peripheral gangrene with Burkholderia multivorans infection.	Yan S, Meng J, Li S.	IDCases	10.1016/j.idcr.2025.e02289	2025
	Immunological studies of Burkholderia multivorans O-antigen oligosaccharide-rsScpA193 conjugates as potential candidates for vaccine development.	Wang G, Zhao J, Zhang X, Li S, Sun C, Gu G.	Int J Biol Macromol	10.1016/j.ijbiomac.2024.138570	2025
	Harnessing membrane vesicles to activate silent bacterial metabolite production.	Yoshimura A, Wakimoto T.	Methods Enzymol	10.1016/bs.mie.2025.01.054	2025
	Teleocidin Analogs Isolated from Streptomyces eurocidicus as Membrane-Vesicle-Regulated Natural Products.	Yoshimura A, Nakada R, Wakimoto T.	Chem Pharm Bull (Tokyo)	10.1248/cpb.c25-00197	2025
	Frameshift Mutations in Genes Encoding PBP3 and PBP4 Trigger an Unusual, Extreme beta-Lactam Resistance Phenotype in Burkholderia multivorans.	Mojica MF, Nukaga M, Becka SA, Zeiser ET, Hoshino T, LiPuma JJ, Papp-Wallace KM.	ACS Infect Dis	10.1021/acsinfecdis.4c00330	2024
	Pulmonary microbial spectrum of Burkholderia multivorans infection identified by metagenomic sequencing.	Xu H, Zhang R, Zhang X, Zhang Z, Feng Y, Lin L.	Front Med (Lausanne)	10.3389/fmed.2025.1577363	2025
Pathogenicity	Case report: Cervical suppurative lymphadenitis caused by burkholderia multivorans in a healthy child.	Niu BB, Xu JJ, Li JA, Zhu LD.	BMC Infect Dis	10.1186/s12879-025-11033-y	2025
Genetics	Characterization and genome analysis of the novel virulent Burkholderia phage Bm1, which is active against pan-drug-resistant Burkholderia multivorans.	Rubalskii E, Sedlacek L, Hegermann J, Knegendorf L, Salmoukas C, Mueller C, Schwerk N, Schluter D, Ruhparwar A, Kuehn C, Ruemke S.	Arch Virol	10.1007/s00705-025-06282-w	2025
	Burkholderia multivorans Infections Associated with Use of Ice and Water from Ice Machines for Patient Care Activities - Four Hospitals, California and Colorado, 2020-2024.	Vazquez Deida AA, Spicer KB, McNamara KX, Arduino MJ, Gable P, Halpin AL, Caverly LJ, LiPuma JJ, Bardach B, Mayle C, Baird SN, Czaja CA, Chinn R, Siegel JD, Perkins KM.	MMWR Morb Mortal Wkly Rep	10.15585/mmwr.mm7339a4	2024
	An Adult-Onset Chronic Granulomatous Disease Case with Hemophagocytic Lymphohistiocytosis Caused by Burkholderia and Aspergillus Infections.	Kaygusuz Y, Ustun C, Er AG, Kiki Z, Yaz I, Tuten-Dal S, Uner A, Cagdas D, Inkaya AC, Akova M.	Infect Dis Clin Microbiol	10.36519/idcm.2024.381	2024
	Synthesis and evaluation of aromatic BDSF bioisosteres on biofilm formation and colistin sensitivity in pathogenic bacteria.	Gomez AC, Horgan C, Yero D, Bravo M, Daura X, O'Driscoll M, Gibert I, O'Sullivan TP.	Eur J Med Chem	10.1016/j.ejmech.2023.115819	2023
Genetics	CRISPR detection in metagenome-assembled genomes (MAGs) of coal mine.	Achudhan AB, Kannan P, Saleena LM.	Funct Integr Genomics	10.1007/s10142-023-01046-8	2023
Biotechnology	Flours from Spondias mombin and Spondias tuberosa seeds: Physicochemical characterization, technological properties, and antioxidant, antibacterial, and antidiabetic activities.	Oliveira FCM, Holanda TMV, de Assis CF, Xavier Junior FH, de Sousa Junior FC.	J Food Sci	10.1111/1750-3841.16882	2024
	Membrane-Vesicle-Mediated Interbacterial Communication Activates Silent Secondary Metabolite Production.	Yoshimura A, Saeki R, Nakada R, Tomimoto S, Jomori T, Suganuma K, Wakimoto T.	Angew Chem Int Ed Engl	10.1002/anie.202307304	2023
	Diagnostic challenge in veterinary pathology: Otitis in a humanized NOG-EXL mouse.	Willis E, Verrelle J, Secreto A, Cole SD, McClung G, Weinfurtner KM, Gade TPF, Radaelli E.	Vet Pathol	10.1177/03009858241279141	2025
	National Cohort of Compassionate Use of Meropenem-Vaborbactam: No Benefit over Meropenem for Pseudomonas aeruginosa.	Dinh A, Bleibtreu A, Duran C, Bouchand F, Bosch A, Crozon-Clauzel J, Roncato-Saberan M, Matt M, Boibieux A, Fanton A, Wille H, Fiaux E, Pilmis B, Lacoste M, Saint-Genis Q, Thumerelle C, Pavese P, Vuotto F, Senneville E, Potron A, Corvec S, Boutoille D, Jeannot K, Dortet L, On Behalf Of The Meropenem-Vaborbactam French Study Group.	Antibiotics (Basel)	10.3390/antibiotics13121152	2024
	Interspecies Crosstalk via LuxI/LuxR-Type Quorum Sensing Pathways Contributes to Decreased Nematode Survival in Coinfections of Pseudomonas aeruginosa and Burkholderia multivorans.	Slinger BL, Banerjee S, Chandler JR, Blackwell HE.	ACS Chem Biol	10.1021/acschembio.4c00641	2024
Pathogenicity	Exploring phage-host interactions in Burkholderia cepacia complex bacterium to reveal host factors and phage resistance genes using CRISPRi functional genomics and transcriptomics.	Diaz B, Krishna R, Schoeniger JS, Mageeney CM.	Microbiol Spectr	10.1128/spectrum.01936-25	2025
	Genome-wide analysis of Burkholderia for the management of antimicrobial-resistant in cystic fibrosis patients.	Magizhvannan V, Veerappapillai S.	AMB Express	10.1186/s13568-025-01926-1	2025
Genetics	Genomic editing in Burkholderia multivorans by CRISPR/Cas9.	Ferreira MR, Queiroga V, Moreira LM.	Appl Environ Microbiol	10.1128/aem.02250-23	2024
	Experimental infection of bed bugs (Cimex lectularius L.) with Burkholderia multivorans.	Peta V, Pietri JE.	Med Vet Entomol	10.1111/mve.12520	2021
	Various Aspects of Bacterial Infections in the Early Postoperative Stage Among Lung Transplant Recipients on Broad-Spectrum Antibiotics: A Single Center Study.	Pioro A, Latos M, Urlik M, Stacel T, Zawadzki F, Gaweda M, Pandel A, Przybylowski P, Knapik P, Ochman M.	Transplant Proc	10.1016/j.transproceed.2022.02.032	2022
	Effect of Ultraviolet-c (UVc) light and ozone on the survival of Mycobacterium abscessus complex organisms associated with cystic fibrosis.	Moore JE, Millar BC.	Int J Mycobacteriol	10.4103/ijmy.ijmy_87_22	2022
	Exacerbation of chronic renal failure because of inhaled tobramycin in a lung transplant patient.	Mora Cuesta VM, Borja Vargas N, Iturbe Fernandez D, Tello Mena S, Cifrian Martinez JM.	Respir Med Case Rep	10.1016/j.rmcr.2022.101584	2022
	Potential of mean force conformational energy maps for disaccharide linkages of the Burkholderia multivorans exopolysaccharide C1576 in aqueous solution.	Jou IA, Yoo AS, Dionne EV, Brady JW.	Carbohydr Res	10.1016/j.carres.2023.108741	2023
	Chemical susceptibility testing of non-tuberculous mycobacterium strains and other aquatic bacteria: Results of a study for the development of a more sensitive and simple method for the detection of NTM in environmental samples.	Ditommaso S, Giacomuzzi M, Memoli G, Garlasco J, Curtoni A, Iannaccone M, Zotti CM.	J Microbiol Methods	10.1016/j.mimet.2021.106405	2022
Metabolism	A transcriptional regulator, IscR, of Burkholderia multivorans acts as both repressor and activator for transcription of iron-sulfur cluster-biosynthetic isc operon.	Nonoyama S, Kishida K, Sakai K, Nagata Y, Ohtsubo Y, Tsuda M.	Res Microbiol	10.1016/j.resmic.2020.06.005	2020
	Carbapenem-Resistant Burkholderia cepacia Complex Isolates Carrying bla _NDM-1 and bla _NDM-5 in Ventilator-Associated Pneumonia Patients and Contaminated Ventilator Tubing.	Saeed M, Rasheed F, Rasool MH, Hayat S, Khurshid M.	Transbound Emerg Dis	10.1155/2024/3352135	2024
	Rational protein engineering of a ketoacids decarboxylase for efficient production of 1,2,4-butanetriol from arabinose.	Shen X, Xu H, Wang T, Zhang R, Sun X, Yuan Q, Wang J.	Biotechnol Biofuels Bioprod	10.1186/s13068-023-02414-z	2023
	Disparate properties of Burkholderia multivorans and Pseudomonas aeruginosa regarding outer membrane chemical permeabilization to the hydrophobic substances novobiocin and triclosan.	Ruskoski SA, McDonald AA, Bleichner JJ, Aga SS, Boyina K, Champlin FR.	PLoS One	10.1371/journal.pone.0284855	2023
	Eradication of Burkholderia cepacia complex in cystic fibrosis patients with inhalation of amiloride and tobramycin combined with oral cotrimoxazole.	Akkerman-Nijland AM, Rottier BL, Holstein J, Winter RLJ, Touw DJ, Akkerman OW, Koppelman GH.	ERJ Open Res	10.1183/23120541.00055-2023	2023
	A new selective culture medium for isolation of Burkholderia cepacia complex in pharmaceutical industry.	Yu M, Wang S, Zhong Y, Yuan L, An L, Feng D, Liu Z, Ma S.	Front Microbiol	10.3389/fmicb.2025.1631983	2025
	Phage therapy in a lung transplant recipient with cystic fibrosis infected with multidrug-resistant Burkholderia multivorans.	Haidar G, Chan BK, Cho ST, Hughes Kramer K, Nordstrom HR, Wallace NR, Stellfox ME, Holland M, Kline EG, Kozar JM, Kilaru SD, Pilewski JM, LiPuma JJ, Cooper VS, Shields RK, Van Tyne D.	Transpl Infect Dis	10.1111/tid.14041	2023
	Biocatalytic cascade combining an engineered pyranose 2-oxidase and transaminases for the synthesis of amino sugars.	Chuaboon L, Visitsatthawong S, Sookbampen O, Suthin S, Voss M, Wongnate T, Hohne M, Bornscheuer UT, Chaiyen P.	RSC Adv	10.1039/d5ra04556h	2025
	Harnessing the Diversity of Burkholderia spp. Prophages for Therapeutic Potential.	Nordstrom HR, Griffith MP, Rangachar Srinivasa V, Wallace NR, Li A, Cooper VS, Shields RK, Van Tyne D.	Cells	10.3390/cells13050428	2024
	Antibiotic Cycling Reverts Extensive Drug Resistance in Burkholderia multivorans.	Kavanaugh LG, Harrison SK, Flanagan JN, Steck TR.	Antimicrob Agents Chemother	10.1128/aac.00611-21	2021
	Toxic Epidermal Necrolysis Superimposed on Severe Drug Rash With Eosinophilia and Systemic Symptoms Complicated by Fatal Hemophagocytic Lymphohistiocytosis: A Case Report.	Swaminathan G, Miller D, Noff N, Bhutta Z, Muratori J, Rauf F, Patrizi S, Ozkan B, Lopez R.	Cureus	10.7759/cureus.69503	2024
	Campylobacter jejuni uses energy taxis and a dehydrogenase enzyme for l-fucose chemotaxis.	Zhou B, Garber JM, Vlach J, Azadi P, Ng KKS, Escalante-Semerena JC, Szymanski CM.	mBio	10.1128/mbio.02732-23	2023
	Bradyrhizobium japonicum HmuP is an RNA-binding protein that positively controls hmuR operon expression by suppression of a negative regulatory RNA element in the 5' untranslated region.	Wu P, Ong A, O'Brian MR.	Mol Microbiol	10.1111/mmi.15274	2024
	Engineering mixed sugar metabolic channels in Pseudomonas putida to produce vanillic acid.	Wu P, Ding H, Xu Z, Zhang Y, Dang Y, Gao B, Zhang G.	Synth Syst Biotechnol	10.1016/j.synbio.2025.10.002	2026
	New variochelins from soil-isolated Variovorax sp. H002.	Haedar JR, Yoshimura A, Wakimoto T.	Beilstein J Org Chem	10.3762/bjoc.20.63	2024
	An l-fucose-responsive transcription factor cross-regulates the expression of a diverse array of carbohydrate-active enzymes in Trichoderma reesei.	Zhao Q, Gao L, Xu N, Zhang X, Qin Y, Qu Y, Liu G.	PLoS Genet	10.1371/journal.pgen.1011815	2025
Phylogeny	Rapid detection of Burkholderia cepacia complex carrying the 16S rRNA gene in clinical specimens by recombinase-aided amplification.	Fu H, Gan L, Tian Z, Han J, Du B, Xue G, Feng Y, Zhao H, Cui J, Yan C, Feng J, Fan Z, Fu T, Xu Z, Zhang R, Cui X, Du S, Zhou Y, Zhang Q, Cao L, Yuan J.	Front Cell Infect Microbiol	10.3389/fcimb.2022.984140	2022
	Successful ceftazidime-avibactam treatment of post-surgery Burkholderia multivorans genomovar II bacteremia and brain abscesses in a young lung transplanted woman with cystic fibrosis.	Dacco V, Claut L, Piconi S, Castellazzi L, Garbarino F, Teri A, Colombo C.	Transpl Infect Dis	10.1111/tid.13082	2019
	Microbiological Status as a Factor of Airway Complications After Lung Transplantation.	Necki M, Gaweda M, Pandel A, Urlik M, Antonczyk R, Latos M, Wajda-Pokrontka M, Zawadzki F, Przybylowski P, Zembala M, Stacel T, Ochman M.	Transplant Proc	10.1016/j.transproceed.2020.02.111	2020
	Evolutionary Dynamics and Functional Differences in Clinically Relevant Pen beta-Lactamases from Burkholderia spp.	Gu J, Agarwal PK, Bonomo RA, Haider S.	J Chem Inf Model	10.1021/acs.jcim.5c00271	2025
	Convergence of Hypervirulence and Multidrug-Resistance in Burkholderia cepacia Complex Isolates from Patients with COVID-19.	Du M, Chi C, Xiong L, Rong J, Yi M, Zhao Q, Chi X.	Infect Drug Resist	10.2147/idr.s495676	2024
	Bacterial Resistance to Antibiotics and Clonal Spread in COVID-19-Positive Patients on a Tertiary Hospital Intensive Care Unit, Czech Republic.	Doubravska L, Htoutou Sedlakova M, Fiserova K, Pudova V, Urbanek K, Petrzelova J, Roderova M, Langova K, Mezerova K, Kucova P, Axmann K, Kolar M.	Antibiotics (Basel)	10.3390/antibiotics11060783	2022
	Febrile urinary tract infection in an immunocompetent male caused by Burkholderia multivorans- evidence of transmission in a home hot tub.	Rasmussen M, Oldberg K.	IDCases	10.1016/j.idcr.2019.e00553	2019
	The Impact of Antimicrobial Resistance in Cystic Fibrosis.	Vitiello A, Blasi F, Sabbatucci M, Zovi A, Miele F, Ponzo A, Langella R, Boccellino M.	J Clin Med	10.3390/jcm13061711	2024
	Identification of Bed Bugs from Comoros, Using Morphological, Matrix-Assisted Laser Desorption Ionisation Time-of-Flight Mass Spectrometry, and Molecular Biology Tools, and the Detection of Associated Bacteria.	M'madi SA, Zan Diarra A, Berenger JM, Hasnaoui B, Parola P.	Insects	10.3390/insects16020148	2025
	Burkholderia multivorans septicemia in a pediatric liver transplant patient.	Ho SSC, Nashid N, Waters VJ, LiPuma JJ, Zlosnik JEA, Otley A, Somers GR, Kamath BM, Yau YCW.	Am J Transplant	10.1111/ajt.15065	2019
	High-Dose Inhaled Nitric Oxide as Adjunct Therapy in Cystic Fibrosis Targeting Burkholderia multivorans.	Bartley BL, Gardner KJ, Spina S, Hurley BP, Campeau D, Berra L, Yonker LM, Carroll RW.	Case Rep Pediatr	10.1155/2020/1536714	2020
	Myeloperoxidase inhibition decreases morbidity and oxidative stress in mice with cystic fibrosis-like lung inflammation.	Dickerhof N, Huang J, Min E, Michaelsson E, Lindstedt EL, Pearson JF, Kettle AJ, Day BJ.	Free Radic Biol Med	10.1016/j.freeradbiomed.2020.03.001	2020
	The Class A beta-Lactamase Produced by Burkholderia Species Compromises the Potency of Tebipenem against a Panel of Isolates from the United States.	Becka SA, Zeiser ET, LiPuma JJ, Papp-Wallace KM.	Antibiotics (Basel)	10.3390/antibiotics11050674	2022
	Case Report: Community-Acquired Burkholderia cepacia Pneumonia of a Patient with Pulmonary Tuberculosis.	Li Q, Ma LP.	Am J Trop Med Hyg	10.4269/ajtmh.21-1338	2022
Phenotype	Identification of two distinct phylogenomic lineages and model strains for the understudied cystic fibrosis lung pathogen Burkholderia multivorans.	Parfitt KM, Green AE, Connor TR, Neill DR, Mahenthiralingam E.	Microbiology (Reading)	10.1099/mic.0.001366	2023
Genetics	Identification, cloning and expression patterns of the genes related to phosphate solubilization in Burkholderia multivorans WS-FJ9 under different soluble phosphate levels.	Liu YQ, Wang YH, Kong WL, Liu WH, Xie XL, Wu XQ.	AMB Express	10.1186/s13568-020-01032-4	2020
	Relaxed specificity of BcpB transporters mediates interactions between Burkholderia cepacia complex contact-dependent growth inhibition systems.	Elery ZK, Myers-Morales T, Phillips ED, Garcia EC.	mSphere	10.1128/msphere.00303-23	2023
	Examining the activity of cefepime-taniborbactam against Burkholderia cepacia complex and Burkholderia gladioli isolated from cystic fibrosis patients in the United States.	Mojica MF, Zeiser ET, Becka SA, LiPuma JJ, Six DA, Moeck G, Papp-Wallace KM.	Antimicrob Agents Chemother	10.1128/aac.00498-23	2023
	The Cell Envelope Integrity Protein Homologue D0Y85_RS06240 of Stenotrophomonas Confers Multiantibiotic Resistance.	Zhong C, Deng X, Jiang A, Liu Y, Liu Y, Fu J, Cao G.	Can J Infect Dis Med Microbiol	10.1155/2024/7547514	2024
	Multifrequency STD NMR Unveils the Interactions of Antibiotics With Burkholderia multivorans Biofilm Exopolysaccharide.	Nepravishta R, Monaco S, Distefano M, Rizzo R, Cescutti P, Angulo J.	Front Mol Biosci	10.3389/fmolb.2021.727980	2021
	Impact of Herpesvirus Detection via Metagenomic Next-Generation Sequencing in Patients with Lower Respiratory Tract Infections.	Zhang H, Zhang X, Zheng Y, Gu X, Fu Z, Gai W, Wang H.	Infect Drug Resist	10.2147/idr.s484768	2025
	Adaptation of Candida albicans to specific host environments by gain-of-function mutations in transcription factors.	Morschhauser J.	PLoS Pathog	10.1371/journal.ppat.1012643	2024
	A balancing act: investigations on the impact of altered signal sensitivity in bacterial quorum sensing.	Miranda SW, Greenberg EP.	J Bacteriol	10.1128/jb.00249-23	2023
Enzymology	Hydroxysteroid 17-beta dehydrogenase 14 (HSD17B14) is an L-fucose dehydrogenase, the initial enzyme of the L-fucose degradation pathway.	Witecka A, Kazak V, Kwiatkowski S, Kiersztan A, Jagielski AK, Kozminski W, Augustyniak R, Drozak J.	J Biol Chem	10.1016/j.jbc.2024.107501	2024
	In Vitro Activity of Finafloxacin against Panels of Respiratory Pathogens.	Harding SV, Barnes KB, Hawser S, Bentley CE, Vente A.	Antibiotics (Basel)	10.3390/antibiotics12071096	2023
	Toxic Megacolon Burdened with COVID-19 Coinfection-Worsening of an Unfavorable Diagnosis: A Single-Center Retrospective Study.	Rezac T, Klos D, Stasek M, Vrba R, Zboril P, Spicka P.	Life (Basel)	10.3390/life12101545	2022
	Electro-Driven Multi-Enzymatic Cascade Conversion of CO₂ to Ethylene Glycol in Nano-Reactor.	Luan L, Zhang Y, Ji X, Guo B, Song S, Huang Y, Zhang S.	Adv Sci (Weinh)	10.1002/advs.202407204	2024
	Burkholderia multivorans requires species-specific GltJK for entry of a contact-dependent growth inhibition system protein.	Myers-Morales T, Sim MMS, DuCote TJ, Garcia EC.	Mol Microbiol	10.1111/mmi.14783	2021
Metabolism	Phosphate Solubilization and Gene Expression of Phosphate-Solubilizing Bacterium Burkholderia multivorans WS-FJ9 under Different Levels of Soluble Phosphate.	Zeng Q, Wu X, Wang J, Ding X.	J Microbiol Biotechnol	10.4014/jmb.1611.11057	2017
	Gliotoxin and related metabolites as zinc chelators: implications and exploitation to overcome antimicrobial resistance.	Downes SG, Doyle S, Jones GW, Owens RA.	Essays Biochem	10.1042/ebc20220222	2023
	Burkholderia pseudomallei PenI beta-lactamase and variants are potently inhibited by taniborbactam.	Mojica MF, Becka SA, Edwards M, Myers C, Uehara K, Uehara T, Hoshino T, Zeiser ET, Chatwin CL, Six DA, Bonomo RA, Papp-Wallace KM, Nukaga M.	Antimicrob Agents Chemother	10.1128/aac.00787-25	2025
	Cell surface physiology and outer cell envelope impermeability for hydrophobic substances in Burkholderia multivorans.	Ruskoski SA, Champlin FR.	J Med Microbiol	10.1099/jmm.0.000532	2017
Pathogenicity	Reciprocal antibiotic collateral sensitivity in Burkholderia multivorans.	Kavanaugh LG, Flanagan JN, Steck TR.	Int J Antimicrob Agents	10.1016/j.ijantimicag.2020.105994	2020
	Burkholderia multivorans: A rare yet emerging cause of bacterial meningitis.	Peralta DP, Chang AY, Ariza-Hutchinson A, Ho CA.	IDCases	10.1016/j.idcr.2018.01.002	2018
	Phosphate availability modulates the weathering effectiveness and molecular response of Caballeronia mineralivorans PML1(12).	Nouche CB, Sar J, Cochet C, Armengaud J, Turpault MP, Uroz S.	BMC Microbiol	10.1186/s12866-025-04221-y	2025
	Bacterial Community- and Hospital-Acquired Pneumonia in Patients with Critical COVID-19-A Prospective Monocentric Cohort Study.	Doubravska L, Htoutou Sedlakova M, Fiserova K, Klementova O, Turek R, Langova K, Kolar M.	Antibiotics (Basel)	10.3390/antibiotics13020192	2024
	Clinical evaluation of a multiplex droplet digital PCR for diagnosing suspected bloodstream infections: a prospective study.	Peng Y, Xie R, Luo Y, Guo P, Wu Z, Chen Y, Liu P, Deng J, Huang B, Liao K.	Front Cell Infect Microbiol	10.3389/fcimb.2024.1489792	2024
	[Multilocus sequence analysis, biofilm production, antibiotic susceptibility and synergy tests of Burkholderia species in patients with and without cystic fibrosis].	Akisoglu O, Engin D, Saricam S, Mustak HK, Sener B, Hascelik G.	Mikrobiyol Bul	10.5578/mb.67730	2019
	Diabetic foot infection caused by bacteria of the Burkholderia cepacia complex: report of an unusual case and a scoping literature review.	Paes Leme RC, Chaves JRE, Goncalves LCS, Alvim LC, Almeida JRC, Reno LDC.	Rev Inst Med Trop Sao Paulo	10.1590/s1678-9946202264036	2022
	Extended Reality Head-Mounted Displays Are Likely to Pose a Significant Risk in Medical Settings While Current Classification Remains as Non-Critical.	Goldsworthy A, Olsen M, Koh A, Demaneuf T, Singh G, Almheiri R, Chapman B, Almazrouei S, Ghemrawi R, Senok A, McKirdy S, Alghafri R, Tajouri L.	Microorganisms	10.3390/microorganisms12040815	2024
	Drivers of diversification in fungal pathogen populations.	Murante D, Hogan DA.	PLoS Pathog	10.1371/journal.ppat.1012430	2024
	Proteomic Studies of the Biofilm Matrix including Outer Membrane Vesicles of Burkholderia multivorans C1576, a Strain of Clinical Importance for Cystic Fibrosis.	Teran LC, Distefano M, Bellich B, Petrosino S, Bertoncin P, Cescutti P, Sblattero D.	Microorganisms	10.3390/microorganisms8111826	2020
	Elexacaftor, tezacaftor and ivacaftor: a case of severe rash and approach to desensitisation.	Cheng A, Baker O, Hill U.	BMJ Case Rep	10.1136/bcr-2021-247042	2022
	Are Burkholderia Emerging Pathogens in patients with underlying morbidity: A case series.	Kumari S, Banu M, Ramanatha K, Barani R, Sridharan KS.	Heliyon	10.1016/j.heliyon.2024.e33283	2024
Phylogeny	Extensive cultivation of soil and water samples yields various pathogens in patients with cystic fibrosis but not Burkholderia multivorans.	Peeters C, Depoorter E, Praet J, Vandamme P.	J Cyst Fibros	10.1016/j.jcf.2016.02.014	2016
	The Use of Medical Grade Honey on Infected Chronic Diabetic Foot Ulcers-A Prospective Case-Control Study.	Holubova A, Chlupacova L, Krocova J, Cetlova L, Peters LJF, Cremers NAJ, Pokorna A.	Antibiotics (Basel)	10.3390/antibiotics12091364	2023
	Skull base osteomyelitis by Pandoraea apista: An unusual pathogen at unusual location - A case report.	Patil NR, Tripathi M, Charaya K, Angrup A, Ahuja C, Mohindra S.	Surg Neurol Int	10.25259/sni_472_2021	2021
	In vitro and in vivo activity of cefiderocol against Achromobacter spp. and Burkholderia cepacia complex, including carbapenem-non-susceptible isolates.	Takemura M, Nakamura R, Ota M, Nakai R, Sahm DF, Hackel MA, Yamano Y.	Antimicrob Agents Chemother	10.1128/aac.00346-23	2023
Enzymology	The polysaccharide extracted from the biofilm of Burkholderia multivorans strain C1576 binds hydrophobic species and exhibits a compact 3D-structure.	Bellich B, Distefano M, Syrgiannis Z, Bosi S, Guida F, Rizzo R, Brady JW, Cescutti P.	Int J Biol Macromol	10.1016/j.ijbiomac.2019.06.140	2019
	Genomics of an endemic cystic fibrosis Burkholderia multivorans strain reveals low within-patient evolution but high between-patient diversity.	Lood C, Peeters C, Lamy-Besnier Q, Wagemans J, De Vos D, Proesmans M, Pirnay JP, Echahidi F, Pierard D, Thimmesch M, Boeras A, Lagrou K, De Canck E, De Wachter E, van Noort V, Lavigne R, Vandamme P.	PLoS Pathog	10.1371/journal.ppat.1009418	2021
	Solar-driven sugar production directly from CO₂ via a customizable electrocatalytic-biocatalytic flow system.	Liu G, Zhong Y, Liu Z, Wang G, Gao F, Zhang C, Wang Y, Zhang H, Ma J, Hu Y, Chen A, Pan J, Min Y, Tang Z, Gao C, Xiong Y.	Nat Commun	10.1038/s41467-024-46954-w	2024
	Characterization of proteins from the 3N5M family reveals an operationally stable amine transaminase.	Kollipara M, Matzel P, Sowa M, Brott S, Bornscheuer U, Hohne M.	Appl Microbiol Biotechnol	10.1007/s00253-022-12071-1	2022
	Dot Immunobinding Assay for the Rapid Serodetection of Scedosporium/Lomentospora in Cystic Fibrosis Patients.	Martin-Souto L, Antoran A, Areitio M, Aparicio-Fernandez L, Martin-Gomez MT, Fernandez R, Astigarraga E, Barreda-Gomez G, Schwarz C, Rickerts V, Hernando FL, Rementeria A, Buldain I, Ramirez-Garcia A.	J Fungi (Basel)	10.3390/jof9020158	2023
	Activity of Imipenem-Relebactam against Multidrug- and Extensively Drug-Resistant Burkholderia cepacia Complex and Burkholderia gladioli.	Becka SA, Zeiser ET, LiPuma JJ, Papp-Wallace KM.	Antimicrob Agents Chemother	10.1128/aac.01332-21	2021
Genetics	Virome and metagenomic analysis reveal the distinct distribution of microbiota in human fetal gut during gestation.	Liu X, He G, Lan Y, Guo W, Liu X, Li J, Liu A, He M, Liu X, Fan Z, Zhang Y.	Front Immunol	10.3389/fimmu.2022.1079294	2022
	Atypical Cystic Fibrosis: Diagnosis at the Age of 57 Years.	Sagesse GJ, Yadava S, Mandava A.	Cureus	10.7759/cureus.10863	2020
Phylogeny	Research on the establishment and application of protein fingerprint spectrum database of Burkholderia pseudomallei in Hainan Province China.	Huang MH, Wu H, Liu LL, Wang XM.	New Microbes New Infect	10.1016/j.nmni.2021.100938	2021
	Mucoid Staphylococcus haemolyticus: an unheeded multidrug-resistant pathogen.	Singhal L, Gupta V, Sharma S, Agarwal A, Gupta P.	Braz J Microbiol	10.1007/s42770-022-00901-3	2023
	Diagnosis of biofilm infections in cystic fibrosis patients.	Hoiby N, Bjarnsholt T, Moser C, Jensen PO, Kolpen M, Qvist T, Aanaes K, Pressler T, Skov M, Ciofu O.	APMIS	10.1111/apm.12689	2017
Enzymology	Prevalence of Burkholderia cepacia complex species in cystic fibrosis patients in Argentina during the period 2011-2015.	Cipolla L, Rocca F, Martinez C, Aguerre L, Barrios R, Prieto M.	Enferm Infecc Microbiol Clin (Engl Ed)	10.1016/j.eimc.2017.09.002	2018
	Decoding interactions between biofilms and DNA nanoparticles.	Sousa A, Kulkarni R, Johannessen M, Wohland T, Skalko-Basnet N, Obuobi S.	Biofilm	10.1016/j.bioflm.2025.100260	2025
	Prevalence of Burkholderia species, including members of Burkholderia cepacia complex, among UK cystic and non-cystic fibrosis patients.	Kenna DTD, Lilley D, Coward A, Martin K, Perry C, Pike R, Hill R, Turton JF.	J Med Microbiol	10.1099/jmm.0.000458	2017
Enzymology	Phage therapy in the management of respiratory and pulmonary infections: a systematic review.	Sarkodie-Addo P, Osman AH, Aglomasa BC, Donkor ES.	Ther Adv Infect Dis	10.1177/20499361241307841	2025
Lipids	A periplasmic phospholipase that maintains outer membrane lipid asymmetry in Pseudomonas aeruginosa.	Guest RL, Lee MJ, Wang W, Silhavy TJ.	Proc Natl Acad Sci U S A	10.1073/pnas.2302546120	2023
	Detection of the etiological agents of hospital-acquired pneumonia - validity and comparison of different types of biological sample collection: a prospective, observational study in intensive care patients.	Doubravska L, Uvizl R, Herkel T, Kolar M, Gabrhelik T, Roderova M, Htoutou Sedlakova M, Langova K, Kolek V, Jakubec P, Adamus M.	Epidemiol Mikrobiol Imunol		2017
	Clinical characteristics and prognosis of pneumonia-related bloodstream infections in the intensive care unit: a single-center retrospective study.	Liu Y, Sun T, Cai Y, Zhai T, Huang L, Zhang Q, Wang C, Chen H, Huang X, Li M, Xia J, Gu S, Guo L, Yang B, Wu X, Lu B, Zhan Q.	Front Public Health	10.3389/fpubh.2023.1249695	2023
	Insights into Enzyme Reactions with Redox Cofactors in Biological Conversion of CO₂.	Kang DK, Kim SH, Sohn JH, Sung BH.	J Microbiol Biotechnol	10.4014/jmb.2306.06005	2023
Pathogenicity	Combination antimicrobial susceptibility testing of Burkholderia cepacia complex: significance of species.	Abbott FK, Milne KE, Stead DA, Gould IM.	Int J Antimicrob Agents	10.1016/j.ijantimicag.2016.07.020	2016
	Examining changes in bacterial abundance in complex communities using next-generation sequencing is enhanced with quantitative PCR.	Stokell JR, Hamp TJ, Steck TR.	Antonie Van Leeuwenhoek	10.1007/s10482-016-0707-4	2016
Genetics	Genome-Wide Association Studies (GWAS) Approaches for the Detection of Genetic Variants Associated with Antibiotic Resistance: A Systematic Review.	Mosquera-Rendon J, Moreno-Herrera CX, Robledo J, Hurtado-Paez U.	Microorganisms	10.3390/microorganisms11122866	2023
Metabolism	An enantioselective amidase from Burkholderia multivorans for the stereoselective synthesis of esfenvalerate.	Lee SH, Park OJ, Shin HJ.	J Microbiol Biotechnol	10.4014/jmb.1401.01019	2014
	Ramachandran conformational energy maps for disaccharide linkages found in Burkholderia multivorans biofilm polysaccharides.	Jou IA, Caterino M, Schnupf U, Rizzo R, Cescutti P, Brady JW.	Int J Biol Macromol	10.1016/j.ijbiomac.2019.11.037	2020
	Assessing the Potency of beta-Lactamase Inhibitors with Diverse Inactivation Mechanisms against the PenA1 Carbapenemase from Burkholderia multivorans.	Nukaga M, Yoon MJ, Taracilia MA, Hoshino T, Becka SA, Zeiser ET, Johnson JR, Papp-Wallace KM.	ACS Infect Dis	10.1021/acsinfecdis.0c00682	2021
	Phage Milagro: a platform for engineering a broad host range virulent phage for Burkholderia.	Yao G, Le T, Korn AM, Peterson HN, Liu M, Gonzalez CF, Gill JJ.	J Virol	10.1128/jvi.00850-23	2023
	A Histone-Like Nucleoid Structuring Protein Regulates Several Virulence Traits in Burkholderia multivorans.	Gomes SC, Ferreira MR, Tavares AF, Silva IN, Becker JD, Moreira LM.	Appl Environ Microbiol	10.1128/aem.00369-21	2021
Phylogeny	Burkholderia cepacia complex in cystic fibrosis in a Brazilian reference center.	Dentini P, Marson FAL, Bonadia LC, Bertuzzo CS, Ribeiro AF, Levy CE, Ribeiro JD.	Med Microbiol Immunol	10.1007/s00430-017-0521-2	2017
Pathogenicity	Probing the size limit for nanomedicine penetration into Burkholderia multivorans and Pseudomonas aeruginosa biofilms.	Forier K, Messiaen AS, Raemdonck K, Nelis H, De Smedt S, Demeester J, Coenye T, Braeckmans K.	J Control Release	10.1016/j.jconrel.2014.07.061	2014
	A thermostable organic solvent-tolerant lipase from Brevibacillus sp.: production and integrated downstream processing using an alcohol-salt-based aqueous two-phase system.	Leykun S, Johansson E, Vetukuri RR, Ceresino EB, Gessesse A.	Front Microbiol	10.3389/fmicb.2023.1270270	2023
	Synthesis of the tetrasaccharide outer core fragment of Burkholderia multivorans lipooligosaccharide.	Ziaco M, De Castro C, Silipo A, Corsaro MM, Molinaro A, Iadonisi A, Lanzetta R, Parrilli M, Bedini E.	Carbohydr Res	10.1016/j.carres.2014.04.018	2015
Genetics	ProPan: a comprehensive database for profiling prokaryotic pan-genome dynamics.	Zhang Y, Zhang H, Zhang Z, Qian Q, Zhang Z, Xiao J.	Nucleic Acids Res	10.1093/nar/gkac832	2023
	Conservation of Resistance-Nodulation-Cell Division Efflux Pump-Mediated Antibiotic Resistance in Burkholderia cepacia Complex and Burkholderia pseudomallei Complex Species.	Somprasong N, Yi J, Hall CM, Webb JR, Sahl JW, Wagner DM, Keim P, Currie BJ, Schweizer HP.	Antimicrob Agents Chemother	10.1128/aac.00920-21	2021
	Cell envelope phospholipid composition of Burkholderia multivorans.	Ruskoski SA, Bullard JW, Champlin FR.	Curr Microbiol	10.1007/s00284-014-0599-3	2014
Pathogenicity	Burkholderia multivorans Exhibits Antibiotic Collateral Sensitivity.	Flanagan JN, Kavanaugh L, Steck TR.	Microb Drug Resist	10.1089/mdr.2019.0202	2020
Pathogenicity	Abnormal blood microbiota profiles are associated with inflammation and immune restoration in HIV/AIDS individuals.	Guo X, Wang Z, Qu M, Guo Y, Yu M, Hong W, Zhang C, Fan X, Song J, Xu R, Zhang J, Huang H, Linghu E, Wang F-S, Sun L, Jiao Y-M.	mSystems	10.1128/msystems.00467-23	2023
Metabolism	A Data-Driven Approach to Enhance the Prediction of Bacteria-Metabolite Interactions in the Human Gut Microbiome Using Enzyme Encodings and Metabolite Structural Embeddings.	Srivastava G, Brylinski M.	Nutrients	10.3390/nu17030469	2025
Genetics	Homologous recombination shapes the architecture and evolution of bacterial genomes.	Torrance EL, Diop A, Bobay LM.	Nucleic Acids Res	10.1093/nar/gkae1265	2025
	Inhibition of co-colonizing cystic fibrosis-associated pathogens by Pseudomonas aeruginosa and Burkholderia multivorans.	Costello A, Reen FJ, O'Gara F, Callaghan M, McClean S.	Microbiology (Reading)	10.1099/mic.0.074203-0	2014
	Soleris® Automated System for the Rapid Detection of Burkholderia cepacia Complex in Cosmetic Products.	Zhang L, Tolan J, Lavigne N, Montei C, Donofrio R, Biswas P.	J AOAC Int	10.1093/jaoacint/qsac109	2022
Enzymology	An evaluation of different steam disinfection protocols for cystic fibrosis nebulizers.	Hohenwarter K, Prammer W, Aichinger W, Reychler G.	J Cyst Fibros	10.1016/j.jcf.2015.07.005	2016
Phylogeny	Accurate identification of members of the Burkholderia cepacia complex in cystic fibrosis sputum.	Martinucci M, Roscetto E, Iula VD, Votsi A, Catania MR, De Gregorio E.	Lett Appl Microbiol	10.1111/lam.12537	2016
Enzymology	An outbreak of Burkholderia multivorans beyond cystic fibrosis patients.	Hanulik V, Webber MA, Chroma M, Uvizl R, Holy O, Whitehead RN, Baugh S, Matouskova I, Kolar M.	J Hosp Infect	10.1016/j.jhin.2013.04.001	2013
	Sequence heterogeneity of the PenA carbapenemase in clinical isolates of Burkholderia multivorans.	Becka SA, Zeiser ET, Marshall SH, Gatta JA, Nguyen K, Singh I, Greco C, Sutton GG, Fouts DE, LiPuma JJ, Papp-Wallace KM.	Diagn Microbiol Infect Dis	10.1016/j.diagmicrobio.2018.06.005	2018
	Draft Genome Sequences of Two Burkholderia multivorans Sequential Isolates from a Chronic Lung Infection of a Cystic Fibrosis Patient.	Silva IN, Santos PM, Moreira LM.	Genome Announc	10.1128/genomea.01531-14	2015
Metabolism	Characteristics of Organic Acid Secretion Associated with the Interaction between Burkholderia multivorans WS-FJ9 and Poplar Root System.	Li GX, Wu XQ, Ye JR, Yang HC.	Biomed Res Int	10.1155/2018/9619724	2018
	HemU and TonB1 contribute to hemin acquisition in Stenotrophomonas maltophilia.	Liao CH, Lu HF, Yang CW, Yeh TY, Lin YT, Yang TC.	Front Cell Infect Microbiol	10.3389/fcimb.2024.1380976	2024
	Burkholderia cepacia Complex Contact-Dependent Growth Inhibition Systems Mediate Interbacterial Competition.	Myers-Morales T, Oates AE, Byrd MS, Garcia EC.	J Bacteriol	10.1128/jb.00012-19	2019
Metabolism	Growth on mannitol-rich media elicits a genome-wide transcriptional response in Burkholderia multivorans that impacts on multiple virulence traits in an exopolysaccharide-independent manner.	Denman CC, Robinson MT, Sass AM, Mahenthiralingam E, Brown AR.	Microbiology (Reading)	10.1099/mic.0.072975-0	2014
Pathogenicity	The Gut and the Translocated Microbiomes in HIV Infection: Current Concepts and Future Avenues.	Nganou-Makamdop K, Douek DC.	Pathog Immun	10.20411/pai.v9i1.693	2024
	Phenazines and toxoflavin act as interspecies modulators of resilience to diverse antibiotics.	Meirelles LA, Newman DK.	Mol Microbiol	10.1111/mmi.14915	2022
Pathogenicity	Rapid emergence of a ceftazidime-resistant Burkholderia multivorans strain in a cystic fibrosis patient.	Stokell JR, Gharaibeh RZ, Steck TR.	J Cyst Fibros	10.1016/j.jcf.2013.01.009	2013
	Distinct Pathogenic Patterns of Burkholderia pseudomallei Isolates Selected from Caenorhabditis elegans and Dictyostelium discoideum Models.	Chen YL, Hsu DW, Hsueh PT, Chen JA, Shih PJ, Lee S, Lin HH, Chen YS.	Am J Trop Med Hyg	10.4269/ajtmh.19-0052	2019
Metabolism	Denitrification by cystic fibrosis pathogens - Stenotrophomonas maltophilia is dormant in sputum.	Kolpen M, Kragh KN, Bjarnsholt T, Line L, Hansen CR, Dalboge CS, Hansen N, Kuhl M, Hoiby N, Jensen PO.	Int J Med Microbiol	10.1016/j.ijmm.2014.07.002	2015
Metabolism	Surfactant aided biodegradation of NAPLs by Burkholderia multivorans: comparison between Triton X-100 and rhamnolipid JBR-515.	Mohanty S, Mukherji S.	Colloids Surf B Biointerfaces	10.1016/j.colsurfb.2012.08.064	2013
	Assessing the suitability of pitaya plant varieties for cultivation in the arid climate of Saudi Arabia.	Al-Qthanin R, Salih AMME, Mohammed A Alhafidh F, Almoghram SAM, Alshehri GA, Alahmari NH.	Heliyon	10.1016/j.heliyon.2023.e21651	2024
Metabolism	Mannitol promotes adherence of an outbreak strain of Burkholderia multivorans via an exopolysaccharide-independent mechanism that is associated with upregulation of newly identified fimbrial and afimbrial adhesins.	Denman CC, Brown AR.	Microbiology (Reading)	10.1099/mic.0.064832-0	2013
	The mycobacterium lipid transporter MmpL3 is dimeric in detergent solution, SMALPs and reconstituted nanodiscs.	Cioccolo S, Barritt JD, Pollock N, Hall Z, Babuta J, Sridhar P, Just A, Morgner N, Dafforn T, Gould I, Byrne B.	RSC Chem Biol	10.1039/d4cb00110a	2024
	Evaluation of Antimicrobial Susceptibility Testing Methods for Burkholderia cenocepacia and Burkholderia multivorans Isolates from Cystic Fibrosis Patients.	Huse HK, Lee MJ, Wootton M, Sharp SE, Traczewski M, LiPuma JJ, Jorth P.	J Clin Microbiol	10.1128/jcm.01447-21	2021
Metabolism	Impact of ozonation pre-treatment of oil sands process-affected water on the operational performance of a GAC-fluidized bed biofilm reactor.	Islam MS, Dong T, McPhedran KN, Sheng Z, Zhang Y, Liu Y, Gamal El-Din M.	Biodegradation	10.1007/s10532-014-9701-6	2014
Enzymology	[Detection of Burkholderia cepacia complex strains in the University Hospital Olomouc].	Hanulik V, Chroma M, Webber MA, Uvizl R, Whitehead RN, Baugh S, Htoutou Sedlakova M, Kolar M.	Klin Mikrobiol Infekc Lek		2012
Pathogenicity	Unraveling Burkholderia cenocepacia H111 fitness determinants using two animal models.	Paszti S, Gualdi S, Torres M, Augusto L, Harrison F, Eberl L.	mSystems	10.1128/msystems.01354-24	2025
	In-Silico Analysis Highlights the Existence in Members of Burkholderia cepacia Complex of a New Class of Adhesins Possessing Collagen-like Domains.	Estevens R, Mil-Homens D, Fialho AM.	Microorganisms	10.3390/microorganisms11051118	2023
	Septic Transfusion Reactions Involving Burkholderia cepacia Complex: A Review.	Salamanca-Pachon M, Guayacan-Fuquene NI, Garcia-Otalora MA.	Microorganisms	10.3390/microorganisms12010040	2023
Enzymology	Burkholderia species infections in patients with cystic fibrosis in British Columbia, Canada. 30 years' experience.	Zlosnik JE, Zhou G, Brant R, Henry DA, Hird TJ, Mahenthiralingam E, Chilvers MA, Wilcox P, Speert DP.	Ann Am Thorac Soc	10.1513/annalsats.201408-395oc	2015
	Burkholderia multivorans survival and trafficking within macrophages.	Schmerk CL, Valvano MA.	J Med Microbiol	10.1099/jmm.0.051243-0	2013
Pathogenicity	Identification of synergists that potentiate the action of polymyxin B against Burkholderia cenocepacia.	Loutet SA, El-Halfawy OM, Jassem AN, Lopez JM, Medarde AF, Speert DP, Davies JE, Valvano MA.	Int J Antimicrob Agents	10.1016/j.ijantimicag.2015.05.010	2015
	The Plasmodium falciparum NCR1 transporter is an antimalarial target that exports cholesterol from the parasite's plasma membrane.	Zhang Z, Lyu M, Han X, Bandara S, Cui M, Istvan ES, Geng X, Tringides ML, Gregor WD, Miyagi M, Oberstaller J, Adams JH, Zhang Y, Nieman MT, von Lintig J, Goldberg DE, Yu EW.	Sci Adv	10.1126/sciadv.adq6651	2024
	Pivotal role of anthranilate dioxygenase genes in the adaptation of Burkholderia multivorans ATCC 17616 in soil.	Nishiyama E, Ohtsubo Y, Yamamoto Y, Nagata Y, Tsuda M.	FEMS Microbiol Lett	10.1111/j.1574-6968.2012.02532.x	2012
Metabolism	Suppression of pleiotropic phenotypes of a Burkholderia multivorans fur mutant by oxyR mutation.	Kimura A, Yuhara S, Ohtsubo Y, Nagata Y, Tsuda M.	Microbiology (Reading)	10.1099/mic.0.057372-0	2012
	Ancient dental calculus reveals oral microbiome shifts associated with lifestyle and disease in Great Britain.	Gancz AS, Farrer AG, Nixon MP, Wright S, Arriola L, Adler C, Davenport ER, Gully N, Cooper A, Britton K, Dobney K, Silverman JD, Weyrich LS.	Nat Microbiol	10.1038/s41564-023-01527-3	2023
	In Vitro Activities of beta-Lactam-beta-Lactamase Inhibitor Antimicrobial Agents against Cystic Fibrosis Respiratory Pathogens.	Caverly LJ, Spilker T, Kalikin LM, Stillwell T, Young C, Huang DB, LiPuma JJ.	Antimicrob Agents Chemother	10.1128/aac.01595-19	2019
	Screening microorganisms for insulin binding reveals binding by Burkholderia multivorans and Burkholderia cenocepacia and novel attachment of insulin to Aeromonas salmonicida via the A-layer.	Nisr RB, Moody AJ, Gilpin ML.	FEMS Microbiol Lett	10.1111/j.1574-6968.2011.02484.x	2012
	Burkholderia multivorans acts as an antagonist against the growth of Burkholderia pseudomallei in soil.	Lin HH, Chen YS, Li YC, Tseng IL, Hsieh TH, Buu LM, Chen YL.	Microbiol Immunol	10.1111/j.1348-0421.2011.00365.x	2011
Genetics	Comparative Genome Analyses Provide Insight into the Antimicrobial Activity of Endophytic Burkholderia.	Jia J, Lu SE.	Microorganisms	10.3390/microorganisms12010100	2024
	A Burkholderia cenocepacia gene encoding a non-functional tyrosine phosphatase is required for the delayed maturation of the bacteria-containing vacuoles in macrophages.	Andrade A, Andrade A, Valvano MA.	Microbiology (Reading)	10.1099/mic.0.077206-0	2014
Metabolism	Role and Function of Class III LitR, a Photosensor Homolog from Burkholderia multivorans.	Sumi S, Shiratori-Takano H, Ueda K, Takano H.	J Bacteriol	10.1128/jb.00285-18	2018
	Burkholderia cepacia complex Cervical Osteomyelitis in an Intravenous Drug User.	Li SK, Messer WB.	Case Rep Infect Dis	10.1155/2018/7638639	2018
Metabolism	Characterization of the AmpC beta-Lactamase from Burkholderia multivorans.	Becka SA, Zeiser ET, Barnes MD, Taracila MA, Nguyen K, Singh I, Sutton GG, LiPuma JJ, Fouts DE, Papp-Wallace KM.	Antimicrob Agents Chemother	10.1128/aac.01140-18	2018
Cultivation	A New Culture Method for the Detection of Non-Tuberculous Mycobacteria in Water Samples from Heater-Cooler Units and Extracorporeal Membrane Oxygenation Machines.	Ditommaso S, Giacomuzzi M, Memoli G, Garlasco J, Curtoni A, Iannaccone M, Zotti CM.	Int J Environ Res Public Health	10.3390/ijerph191710645	2022
Pathogenicity	Activity of Tobramycin against Cystic Fibrosis Isolates of Burkholderia cepacia Complex Grown as Biofilms.	Kennedy S, Beaudoin T, Yau YC, Caraher E, Zlosnik JE, Speert DP, LiPuma JJ, Tullis E, Waters V.	Antimicrob Agents Chemother	10.1128/aac.02068-15	2016
	Biofilm formation is correlated with low nutrient and simulated microgravity conditions in a Burkholderia isolate from the ISS water processor assembly.	Diaz A, Dixit AR, Khodadad CL, Hummerick ME, Justiano-Velez YA, Li W, O'Rourke A.	Biofilm	10.1016/j.bioflm.2023.100110	2023
	Sessile Lifestyle Offers Protection against Copper Stress in Saccharolobus solfataricus.	Recalde A, Gonzalez-Madrid G, Acevedo-Lopez J, Jerez CA.	Microorganisms	10.3390/microorganisms11061421	2023
Pathogenicity	Discovery of Ubonodin, an Antimicrobial Lasso Peptide Active against Members of the Burkholderia cepacia Complex.	Cheung-Lee WL, Parry ME, Zong C, Cartagena AJ, Darst SA, Connell ND, Russo R, Link AJ.	Chembiochem	10.1002/cbic.201900707	2020
Pathogenicity	Human Cryptic Host Defence Peptide GVF27 Exhibits Anti-Infective Properties against Biofilm Forming Members of the Burkholderia cepacia Complex.	Bosso A, Gaglione R, Di Girolamo R, Veldhuizen EJA, Garcia-Vello P, Fusco S, Cafaro V, Monticelli M, Culurciello R, Notomista E, Arciello A, Pizzo E.	Pharmaceuticals (Basel)	10.3390/ph15020260	2022
Metabolism	The State of the Nitric Oxide Cycle in Respiratory Tract Diseases.	Soodaeva S, Klimanov I, Kubysheva N, Popova N, Batyrshin I.	Oxid Med Cell Longev	10.1155/2020/4859260	2020
	Identification of Burkholderia multivorans ATCC 17616 genes induced in soil environment by in vivo expression technology.	Nishiyama E, Ohtsubo Y, Nagata Y, Tsuda M.	Environ Microbiol	10.1111/j.1462-2920.2010.02227.x	2010
Metabolism	Characterization of liposomes formed by lipopolysaccharides from Burkholderia cenocepacia, Burkholderia multivorans and Agrobacterium tumefaciens: from the molecular structure to the aggregate architecture.	D'Errico G, Silipo A, Mangiapia G, Vitiello G, Radulescu A, Molinaro A, Lanzetta R, Paduano L.	Phys Chem Chem Phys	10.1039/c0cp00066c	2010
Pathogenicity	"Switching Partners": Piperacillin-Avibactam Is a Highly Potent Combination against Multidrug-Resistant Burkholderia cepacia Complex and Burkholderia gladioli Cystic Fibrosis Isolates.	Zeiser ET, Becka SA, Wilson BM, Barnes MD, LiPuma JJ, Papp-Wallace KM.	J Clin Microbiol	10.1128/jcm.00181-19	2019
	Mucoid morphotype variation of Burkholderia multivorans during chronic cystic fibrosis lung infection is correlated with changes in metabolism, motility, biofilm formation and virulence.	Silva IN, Ferreira AS, Becker JD, Zlosnik JEA, Speert DP, He J, Mil-Homens D, Moreira LM.	Microbiology (Reading)	10.1099/mic.0.050989-0	2011
	Recipient Cell Factors Influence Interbacterial Competition Mediated by Two Distinct Burkholderia dolosa Contact-Dependent Growth Inhibition Systems.	Elery ZK, Oates AE, Myers-Morales T, Garcia EC.	J Bacteriol	10.1128/jb.00541-21	2022
Metabolism	Transport of nanoparticles in cystic fibrosis sputum and bacterial biofilms by single-particle tracking microscopy.	Forier K, Messiaen AS, Raemdonck K, Deschout H, Rejman J, De Baets F, Nelis H, De Smedt SC, Demeester J, Coenye T, Braeckmans K.	Nanomedicine (Lond)	10.2217/nnm.12.129	2013
	Evaluation of antimicrobial susceptibility testing methods for Burkholderia cepacia complex isolates from people with and without cystic fibrosis.	Jorth P, Manuel C, McLemore T, Humphries RM, Cole NC, Schuetz AN, Garica D, Maldonado M, Rivero N, Milesi Galdino AC, Celedonio D, LiPuma JJ, Green DA, Zlosnik JEA, Traczewski M, Huse HK.	J Clin Microbiol	10.1128/jcm.01480-24	2025
	Ideation and assessment of a nitric oxide delivery system for spontaneously breathing subjects.	Gianni S, Morais CCA, Larson G, Pinciroli R, Carroll R, Yu B, Zapol WM, Berra L.	Nitric Oxide	10.1016/j.niox.2020.08.004	2020
Pathogenicity	Case Report: Secondary Hemophagocytic Lymphohistiocytosis With Disseminated Infection in Chronic Granulomatous Disease-A Serious Cause of Mortality.	Squire JD, Vazquez SN, Chan A, Smith ME, Chellapandian D, Vose L, Teppa B, Hanson IC, Chinn IK, Forbes-Satter L, Seeborg FO, Nicholas SK, Martinez CA, Allen CE, Connors TJ, Satwani P, Shtessel M, Ale H, Noroski LM, Rider NL, Milner JD, Leiding JW.	Front Immunol	10.3389/fimmu.2020.581475	2020
	Kosakonia oryziphila NP19 bacterium acts as a plant growth promoter and biopesticide to suppress blast disease in KDML105 rice.	Thanwisai L, Siripornadulsil W, Siripornadulsil S.	Sci Rep	10.1038/s41598-024-68097-0	2024
	The effect of sinus surgery with intensive follow-up on pathogenic sinus bacteria in patients with cystic fibrosis.	Aanaes K, von Buchwald C, Hjuler T, Skov M, Alanin M, Johansen HK.	Am J Rhinol Allergy	10.2500/ajra.2013.27.3829	2013
	Surface-Exposed Protein Moieties of Burkholderia cenocepacia J2315 in Microaerophilic and Aerobic Conditions.	Seixas AMM, Silva C, Marques JMM, Mateus P, Rodriguez-Ortega MJ, Feliciano JR, Leitao JH, Sousa SA.	Vaccines (Basel)	10.3390/vaccines12040398	2024
Metabolism	An RND transporter in the monoterpene metabolism of Castellaniella defragrans.	Puentes-Cala E, Harder J.	Biodegradation	10.1007/s10532-018-9857-6	2019
	Cepacia syndrome in a cystic fibrosis patient colonised with Burkholderia multivorans.	Shafiq I, Carroll MP, Nightingale JA, Daniels TV.	BMJ Case Rep	10.1136/bcr.08.2010.3296	2011
Enzymology	PCR detection of Burkholderia multivorans in water and soil samples.	Peeters C, Daenekindt S, Vandamme P.	BMC Microbiol	10.1186/s12866-016-0801-9	2016
	Antibiotic therapy for chronic infection with Burkholderia cepacia complex in people with cystic fibrosis.	Frost F, Shaw M, Nazareth D.	Cochrane Database Syst Rev	10.1002/14651858.cd013079.pub3	2021
Phylogeny	Draft genome sequence determination for cystic fibrosis and chronic granulomatous disease Burkholderia multivorans isolates.	Varga JJ, Losada L, Zelazny AM, Brinkac L, Harkins D, Radune D, Hostetler J, Sampaio EP, Ronning CM, Nierman WC, Greenberg DE, Holland SM, Goldberg JB.	J Bacteriol	10.1128/jb.01306-12	2012
Pathogenicity	The lipid A of Burkholderia multivorans C1576 smooth-type lipopolysaccharide and its pro-inflammatory activity in a cystic fibrosis airways model.	Ierano T, Cescutti P, Leone MR, Luciani A, Rizzo R, Raia V, Lanzetta R, Parrilli M, Maiuri L, Silipo A, Molinaro A.	Innate Immun	10.1177/1753425909347400	2010
	Phage-antibiotic synergy reduces Burkholderia cenocepacia population.	Mankovich AG, Maciel K, Kavanaugh M, Kistler E, Muckle E, Weingart CL.	BMC Microbiol	10.1186/s12866-022-02738-0	2023
	Structural study and conformational behavior of the two different lipopolysaccharide O-antigens produced by the cystic fibrosis pathogen Burkholderia multivorans.	Ierano T, Silipo A, Cescutti P, Leone MR, Rizzo R, Lanzetta R, Parrilli M, Molinaro A.	Chemistry	10.1002/chem.200900647	2009
Pathogenicity	In Vitro Activity of a Novel Glycopolymer against Biofilms of Burkholderia cepacia Complex Cystic Fibrosis Clinical Isolates.	Narayanaswamy VP, Duncan AP, LiPuma JJ, Wiesmann WP, Baker SM, Townsend SM.	Antimicrob Agents Chemother	10.1128/aac.00498-19	2019
Metabolism	Alteration in cell surface properties of Burkholderia spp. during surfactant-aided biodegradation of petroleum hydrocarbons.	Mohanty S, Mukherji S.	Appl Microbiol Biotechnol	10.1007/s00253-011-3703-7	2012
	Identification by Reverse Vaccinology of Three Virulence Factors in Burkholderia cenocepacia That May Represent Ideal Vaccine Antigens.	Irudal S, Scoffone VC, Trespidi G, Barbieri G, D'Amato M, Viglio S, Pizza M, Scarselli M, Riccardi G, Buroni S.	Vaccines (Basel)	10.3390/vaccines11061039	2023
Enzymology	Crystal structure of AdoMet radical enzyme 7-carboxy-7-deazaguanine synthase from Escherichia coli suggests how modifications near [4Fe-4S] cluster engender flavodoxin specificity.	Grell TAJ, Bell BN, Nguyen C, Dowling DP, Bruender NA, Bandarian V, Drennan CL.	Protein Sci	10.1002/pro.3529	2019
	Survey of Bartonella spp. in U.S. bed bugs detects Burkholderia multivorans but not Bartonella.	Saenz VL, Maggi RG, Breitschwerdt EB, Kim J, Vargo EL, Schal C.	PLoS One	10.1371/journal.pone.0073661	2013
Pathogenicity	Identification of the lipodepsipeptide selethramide encoded in a giant nonribosomal peptide synthetase from a Burkholderia bacterium.	Romanowski SB, Lee S, Kunakom S, Paulo BS, Recchia MJJ, Liu DY, Cavanagh H, Linington RG, Eustaquio AS.	Proc Natl Acad Sci U S A	10.1073/pnas.2304668120	2023
Phylogeny	Diversity analysis of Burkholderia cepacia complex in the water bodies of West Lake, Hangzhou, China.	Fang Y, Xie GL, Lou MM, Li B, Muhammad I.	J Microbiol	10.1007/s12275-011-0267-2	2011
Metabolism	Presence of the Hmq System and Production of 4-Hydroxy-3-Methyl-2-Alkylquinolines Are Heterogeneously Distributed between Burkholderia cepacia Complex Species and More Prevalent among Environmental than Clinical Isolates.	Coulon PML, Zlosnik JEA, Deziel E.	Microbiol Spectr	10.1128/spectrum.00127-21	2021
	Updated Review on Clinically-Relevant Properties of Delafloxacin.	Turban A, Guerin F, Dinh A, Cattoir V.	Antibiotics (Basel)	10.3390/antibiotics12081241	2023
	Crystal structures of the Burkholderia multivorans hopanoid transporter HpnN.	Kumar N, Su CC, Chou TH, Radhakrishnan A, Delmar JA, Rajashankar KR, Yu EW.	Proc Natl Acad Sci U S A	10.1073/pnas.1619660114	2017
Pathogenicity	Resistance of the Burkholderia cepacia complex to fosmidomycin and fosmidomycin derivatives.	Messiaen AS, Verbrugghen T, Declerck C, Ortmann R, Schlitzer M, Nelis H, Van Calenbergh S, Coenye T.	Int J Antimicrob Agents	10.1016/j.ijantimicag.2011.04.020	2011
Metabolism	Pleiotropic roles of iron-responsive transcriptional regulator Fur in Burkholderia multivorans.	Yuhara S, Komatsu H, Goto H, Ohtsubo Y, Nagata Y, Tsuda M.	Microbiology (Reading)	10.1099/mic.0.2007/015537-0	2008
Metabolism	Extracellular Lipase and Protease Production from a Model Drinking Water Bacterial Community Is Functionally Robust to Absence of Individual Members.	Willsey GG, Wargo MJ.	PLoS One	10.1371/journal.pone.0143617	2015
	Community structure of environmental microorganisms associated with COVID-19 affected patients.	Zhang W, Mo G, Yang J, Hu X, Huang H, Zhu J, Zhang P, Xia H, Xie L.	Aerobiologia (Bologna)	10.1007/s10453-021-09708-5	2021
Metabolism	Invasion of Burkholderia cepacia complex isolates into lung epithelial cells involves glycolipid receptors.	Mullen T, Callaghan M, McClean S.	Microb Pathog	10.1016/j.micpath.2010.08.003	2010
Pathogenicity	Use of quorum sensing inhibitors to interfere with biofilm formation and development in Burkholderia multivorans and Burkholderia cenocepacia.	Brackman G, Hillaert U, Van Calenbergh S, Nelis HJ, Coenye T.	Res Microbiol	10.1016/j.resmic.2008.12.003	2009
Metabolism	Macrophage responses to CF pathogens: JNK MAP kinase signaling by Burkholderia cepacia complex lipopolysaccharide.	McKeon S, McClean S, Callaghan M.	FEMS Immunol Med Microbiol	10.1111/j.1574-695x.2010.00712.x	2010
	Differential modulation of innate immune cell functions by the Burkholderia cepacia complex: Burkholderia cenocepacia but not Burkholderia multivorans disrupts maturation and induces necrosis in human dendritic cells.	MacDonald KL, Speert DP.	Cell Microbiol	10.1111/j.1462-5822.2008.01197.x	2008
Metabolism	The structure and proinflammatory activity of the lipopolysaccharide from Burkholderia multivorans and the differences between clonal strains colonizing pre and posttransplanted lungs.	Ierano T, Silipo A, Sturiale L, Garozzo D, Brookes H, Khan CM, Bryant C, Gould FK, Corris PA, Lanzetta R, Parrilli M, De Soyza A, Molinaro A.	Glycobiology	10.1093/glycob/cwn074	2008
Metabolism	The gastrointestinal pathogen Campylobacter jejuni metabolizes sugars with potential help from commensal Bacteroides vulgatus.	Garber JM, Nothaft H, Pluvinage B, Stahl M, Bian X, Porfirio S, Enriquez A, Butcher J, Huang H, Glushka J, Line E, Gerlt JA, Azadi P, Stintzi A, Boraston AB, Szymanski CM.	Commun Biol	10.1038/s42003-019-0727-5	2020
	Antibiotherapy in Children with Cystic Fibrosis-An Extensive Review.	Ciuca IM, Dediu M, Popin D, Pop LL, Tamas LA, Pilut CN, Almajan Guta B, Popa ZL.	Children (Basel)	10.3390/children9081258	2022
Phylogeny	Evidence of coinfection with distinct strains of Burkholderia multivorans in a cystic fibrosis patient.	Wellinghausen N, Kothe J.	Infection	10.1007/s15010-006-5608-4	2006
	The Bep gene cluster in Burkholderia cenocepacia H111 codes for a water-insoluble exopolysaccharide essential for biofilm formation.	Bellich B, Teran LC, Fazli MM, Berti F, Rizzo R, Tolker-Nielsen T, Cescutti P.	Carbohydr Polym	10.1016/j.carbpol.2022.120318	2023
Pathogenicity	The Impact of Intraspecies and Interspecies Bacterial Interactions on Disease Outcome.	Baishya J, Bisht K, Rimbey JN, Yihunie KD, Islam S, Al Mahmud H, Waller JE, Wakeman CA.	Pathogens	10.3390/pathogens10020096	2021
Metabolism	Phenotypic changes in group B streptococci grown in the presence of the polyols, erythritol, sorbitol and mannitol.	Hulbah M, Croxen MA, Tyrrell GJ.	BMC Microbiol	10.1186/s12866-021-02208-z	2021
	Burkholderia ubonensis High-Level Tetracycline Resistance Is Due to Efflux Pump Synergy Involving a Novel TetA(64) Resistance Determinant.	Somprasong N, Hall CM, Webb JR, Sahl JW, Wagner DM, Keim P, Currie BJ, Schweizer HP.	Antimicrob Agents Chemother	10.1128/aac.01767-20	2021
	Clinical and Microbiological Performances and Effects on Lipid and Cytokine Production of a Ceruminolytic Ear Cleaner in Canine Erythemato-Ceruminous Otitis Externa.	Moog F, Mivielle J, Brun J, Dumitrache MO, Amalric N, Lecru LA, Pressanti C, Kondratjeva J, Combarros D, Fantini O, Cadiergues MC.	Vet Sci	10.3390/vetsci9040185	2022
	The OmpR Regulator of Burkholderia multivorans Controls Mucoid-to-Nonmucoid Transition and Other Cell Envelope Properties Associated with Persistence in the Cystic Fibrosis Lung.	Silva IN, Pessoa FD, Ramires MJ, Santos MR, Becker JD, Cooper VS, Moreira LM.	J Bacteriol	10.1128/jb.00216-18	2018
Pathogenicity	Inhibition of Burkholderia multivorans adhesion to lung epithelial cells by bivalent lactosides.	Wright C, Leyden R, Murphy PV, Callaghan M, Velasco-Torrijos T, McClean S.	Molecules	10.3390/molecules170910065	2012
Pathogenicity	Real-time PCR method for the quantification of Burkholderia cepacia complex attached to lung epithelial cells and inhibition of that attachment.	Wright C, Herbert G, Pilkington R, Callaghan M, McClean S.	Lett Appl Microbiol	10.1111/j.1472-765x.2010.02828.x	2010
	Optimization of Early Antimicrobial Strategies for Lung Transplant Recipients Based on Metagenomic Next-Generation Sequencing.	Zhang XQ, Lei Y, Tan XL, Guo L, Huang XB, Yang FX, Yu H, Liu XS, Wang YP, Lu S, Pan LA.	Front Microbiol	10.3389/fmicb.2022.839698	2022
	iTRAQ-Based Quantitative Proteomic Analysis of Acinetobacter baumannii under Hypoxia and Normoxia Reveals the Role of OmpW as a Virulence Factor.	Gil-Marques ML, Pachon J, Smani Y.	Microbiol Spectr	10.1128/spectrum.02328-21	2022
Pathogenicity	Efficacy of various chemical disinfectants on biofilms formed in spacecraft potable water system components.	Wong WC, Dudinsky LA, Garcia VM, Ott CM, Castro VA.	Biofouling	10.1080/08927014.2010.495772	2010
Metabolism	A novel recombinant ethyl ferulate esterase from Burkholderia multivorans.	Rashamuse KJ, Burton SG, Cowan DA.	J Appl Microbiol	10.1111/j.1365-2672.2007.03394.x	2007
	Interactions Between Pathogenic Burkholderia and the Complement System: A Review of Potential Immune Evasion Mechanisms.	Syed I, Wooten RM.	Front Cell Infect Microbiol	10.3389/fcimb.2021.701362	2021
Metabolism	Surface hydrophobicity of petroleum hydrocarbon degrading Burkholderia strains and their interactions with NAPLs and surfaces.	Chakraborty S, Mukherji S, Mukherji S.	Colloids Surf B Biointerfaces	10.1016/j.colsurfb.2010.02.019	2010
Genetics	Geography, niches, and transportation influence bovine respiratory microbiome and health.	Chai J, Liu X, Usdrowski H, Deng F, Li Y, Zhao J.	Front Cell Infect Microbiol	10.3389/fcimb.2022.961644	2022
Metabolism	The Small Protein HemP Is a Transcriptional Activator for the Hemin Uptake Operon in Burkholderia multivorans ATCC 17616.	Sato T, Nonoyama S, Kimura A, Nagata Y, Ohtsubo Y, Tsuda M.	Appl Environ Microbiol	10.1128/aem.00479-17	2017
Metabolism	Fluorescence and NMR spectroscopy together with molecular simulations reveal amphiphilic characteristics of a Burkholderia biofilm exopolysaccharide.	Kuttel MM, Cescutti P, Distefano M, Rizzo R.	J Biol Chem	10.1074/jbc.m117.785048	2017
	Quorum Sensing Protects Pseudomonas aeruginosa against Cheating by Other Species in a Laboratory Coculture Model.	Smalley NE, An D, Parsek MR, Chandler JR, Dandekar AA.	J Bacteriol	10.1128/jb.00482-15	2015
	Approaches to measure the fitness of Burkholderia cepacia complex isolates.	Pope CF, Gillespie SH, Moore JE, McHugh TD.	J Med Microbiol	10.1099/jmm.0.017830-0	2010
	Burkholderia cenocepacia in cystic fibrosis: epidemiology and molecular mechanisms of virulence.	Drevinek P, Mahenthiralingam E.	Clin Microbiol Infect	10.1111/j.1469-0691.2010.03237.x	2010
Pathogenicity	Contact-dependent growth inhibition (CDI) systems deploy a large family of polymorphic ionophoric toxins for inter-bacterial competition.	Halvorsen TM, Schroeder KA, Jones AM, Hammarlof D, Low DA, Koskiniemi S, Hayes CS.	PLoS Genet	10.1371/journal.pgen.1011494	2024
	Riemerella anatipestifer AS87_RS09170 gene is responsible for biotin synthesis, bacterial morphology and virulence.	Ren X, Wang X, Shi H, Zhang X, Chen Z, Malhi KK, Ding C, Yu S.	Sci Rep	10.1038/s41598-018-32905-1	2018
Metabolism	Molecular characterization of a novel family VIII esterase from Burkholderia multivorans UWC10.	Rashamuse KJ, Burton SG, Stafford WH, Cowan DA.	J Mol Microbiol Biotechnol	10.1159/000103610	2007
Pathogenicity	Divergent airway microbiomes in lung transplant recipients with or without pulmonary infection.	Pahlman LI, Manoharan L, Aspelund AS.	Respir Res	10.1186/s12931-021-01724-w	2021
Genetics	Genomic features, antimicrobial susceptibility, and epidemiological insights into Burkholderia cenocepacia clonal complex 31 isolates from bloodstream infections in India.	Saroha T, Patil PP, Rana R, Kumar R, Kumar S, Singhal L, Gautam V, Patil PB.	Front Cell Infect Microbiol	10.3389/fcimb.2023.1151594	2023
Genetics	A Phylogeny-Informed Proteomics Approach for Species Identification within the Burkholderia cepacia Complex.	Wang H, Cisse OH, Bolig T, Drake SK, Chen Y, Strich JR, Youn JH, Okoro U, Rosenberg AZ, Sun J, LiPuma JJ, Suffredini AF, Dekker JP.	J Clin Microbiol	10.1128/jcm.01741-20	2020
	Epidemiology and molecular characterization of a clone of Burkholderia cenocepacia responsible for nosocomial pulmonary tract infections in a French intensive care unit.	Graindorge A, Menard A, Neto M, Bouvet C, Miollan R, Gaillard S, de Montclos H, Laurent F, Cournoyer B.	Diagn Microbiol Infect Dis	10.1016/j.diagmicrobio.2009.06.008	2010
	Case not Closed: Arguments for New Studies of the Interactions between Bed Bugs and Human Pathogens.	Pietri JE.	Am J Trop Med Hyg	10.4269/ajtmh.20-0121	2020
	Whole-genome sequence of multi-drug resistant Pseudomonas aeruginosa strains UY1PSABAL and UY1PSABAL2 isolated from human broncho-alveolar lavage, Yaoundé, Cameroon.	Madaha EL, Mienie C, Gonsu HK, Bughe RN, Fonkoua MC, Mbacham WF, Alayande KA, Bezuidenhout CC, Ateba CN.	PLoS One	10.1371/journal.pone.0238390	2020
	Burkholderia cepacia complex and limited cutaneous vasculitis in patients with cystic fibrosis: a case series.	Kayria M, Chris O, Dhasmana DJ, Nilesh M, Hodson ME, Khin G, Diana B, Simmonds NJ.	JRSM Open	10.1177/2054270417692732	2017
	Genome Plasticity by Insertion Sequences Learned From a Case of Radiation-Resistant Bacterium Deinococcus geothermalis.	Lee C, Bae MK, Choi N, Lee SJ, Lee SJ.	Bioinform Biol Insights	10.1177/11779322211037437	2021
	Polyphasic characterisation of Burkholderia cepaciacomplex species isolated from children with cystic fibrosis.	Vicenzi FJ, Pillonetto M, Souza HA, Palmeiro JK, Riedi CA, Rosario-Filho NA, Dalla-Costa LM.	Mem Inst Oswaldo Cruz	10.1590/0074-02760150314	2016
	Invasion and biofilm formation of Burkholderia dolosa is comparable with Burkholderia cenocepacia and Burkholderia multivorans.	Caraher E, Duff C, Mullen T, Mc Keon S, Murphy P, Callaghan M, McClean S.	J Cyst Fibros	10.1016/j.jcf.2006.05.007	2007
Enzymology	Novel glycopolymer sensitizes Burkholderia cepacia complex isolates from cystic fibrosis patients to tobramycin and meropenem.	Narayanaswamy VP, Giatpaiboon S, Baker SM, Wiesmann WP, LiPuma JJ, Townsend SM.	PLoS One	10.1371/journal.pone.0179776	2017
Genetics	MLSTar: automatic multilocus sequence typing of bacterial genomes in R.	Ferres I, Iraola G.	PeerJ	10.7717/peerj.5098	2018
	An insight into the role of the organic acids produced by Enterobacter sp. strain 15S in solubilizing tricalcium phosphate: in situ study on cucumber.	Zuluaga MYA, de Oliveira ALM, Valentinuzzi F, Jayme NS, Monterisi S, Fattorini R, Cesco S, Pii Y.	BMC Microbiol	10.1186/s12866-023-02918-6	2023
	Functionally diverse microbial communities show resilience in response to a record-breaking rain event.	Walker JR, Woods AC, Pierce MK, Steichen JL, Quigg A, Kaiser K, Labonte JM.	ISME Commun	10.1038/s43705-022-00162-z	2022
Metabolism	The SlyB outer membrane lipoprotein of Burkholderia multivorans contributes to membrane integrity.	Plesa M, Hernalsteens JP, Vandenbussche G, Ruysschaert JM, Cornelis P.	Res Microbiol	10.1016/j.resmic.2005.11.015	2006
	A genome-wide association analysis reveals a potential role for recombination in the evolution of antimicrobial resistance in Burkholderia multivorans.	Diaz Caballero J, Clark ST, Wang PW, Donaldson SL, Coburn B, Tullis DE, Yau YCW, Waters VJ, Hwang DM, Guttman DS.	PLoS Pathog	10.1371/journal.ppat.1007453	2018
Phylogeny	Use of Fourier transform infrared spectroscopy and chemometrics to discriminate clinical isolates of bacteria of the Burkholderia cepacia complex from different species and ribopatterns.	Coutinho CP, Sa-Correia I, Lopes JA.	Anal Bioanal Chem	10.1007/s00216-009-2908-4	2009
	Investigating the association of bed bugs with infectious diseases: A retrospective case-control study.	Sheele JM, Libertin CR, Pritt BS, Wysokinska EM, Pietri JE.	Heliyon	10.1016/j.heliyon.2021.e08107	2021
	Application of metagenomic next-generation sequencing in the diagnosis of urinary tract infection in patients undergoing cutaneous ureterostomy.	Huang R, Yuan Q, Gao J, Liu Y, Jin X, Tang L, Cao Y.	Front Cell Infect Microbiol	10.3389/fcimb.2023.991011	2023
	Characterization of a Novel Functional Trimeric Catechol 1,2-Dioxygenase From a Pseudomonas stutzeri Isolated From the Gulf of Mexico.	Rodriguez-Salazar J, Almeida-Juarez AG, Ornelas-Ocampo K, Millan-Lopez S, Raga-Carbajal E, Rodriguez-Mejia JL, Muriel-Millan LF, Godoy-Lozano EE, Rivera-Gomez N, Rudino-Pinera E, Pardo-Lopez L.	Front Microbiol	10.3389/fmicb.2020.01100	2020
Enzymology	Transient isolation of Burkholderia multivorans and Burkholderia cenocepacia from a Brazilian cystic fibrosis patient chronically colonized with Burkholderia vietnamiensis.	Carvalho GM, Carvalho AP, Folescu TW, Higa L, Teixeira LM, Plotkowski MC, Merquior VL, Albano RM, Marques EA.	J Cyst Fibros	10.1016/j.jcf.2005.08.002	2005
Enzymology	Mechanical homogenization increases bacterial homogeneity in sputum.	Stokell JR, Khan A, Steck TR.	J Clin Microbiol	10.1128/jcm.00487-14	2014
	Unraveling the role of toxin-antitoxin systems in Burkholderia pseudomallei: exploring bacterial pathogenesis and interactions within the HigBA families.	Chapartegui-Gonzalez I, Stockton JL, Bowser S, Badten AJ, Torres AG.	Microbiol Spectr	10.1128/spectrum.00748-24	2024
	Pretransplant HRCT Characteristics Are Associated with Worse Outcome of Lung Transplantation for Cystic Fibrosis Patients.	Belle-van Meerkerk G, de Jong PA, de Valk HW, Neefjes T, Pameijer FA, Kwakkel-van Erp JM, van de Graaf EA.	PLoS One	10.1371/journal.pone.0145597	2015
	'Cepacia syndrome' with Burkholderia multivorans, 9 years after initial colonization.	Blackburn L, Brownlee K, Conway S, Denton M.	J Cyst Fibros	10.1016/j.jcf.2004.03.007	2004
	Organization and localization of the dnaA and dnaK gene regions on the multichromosomal genome of Burkholderia multivorans ATCC 17616.	Nagata Y, Matsuda M, Komatsu H, Imura Y, Sawada H, Ohtsubo Y, Tsuda M.	J Biosci Bioeng	10.1263/jbb.99.603	2005
	Targeted metagenomics reveals association between severity and pathogen co-detection in infants with respiratory syncytial virus.	Lin GL, Drysdale SB, Snape MD, O'Connor D, Brown A, MacIntyre-Cockett G, Mellado-Gomez E, de Cesare M, Ansari MA, Bonsall D, Bray JE, Jolley KA, Bowden R, Aerssens J, Bont L, Openshaw PJM, Martinon-Torres F, Nair H, Golubchik T, Pollard AJ, RESCEU Consortium.	Nat Commun	10.1038/s41467-024-46648-3	2024
	Involvement of the hemP-hemA-smlt0796-smlt0797 Operon in Hemin Acquisition by Stenotrophomonas maltophilia.	Shih YL, Wu CM, Lu HF, Li LH, Lin YT, Yang TC.	Microbiol Spectr	10.1128/spectrum.00321-22	2022
Enzymology	Single-step purification of lipase from Burkholderia multivorans using polypropylene matrix.	Gupta N, Rathi P, Singh R, Goswami VK, Gupta R.	Appl Microbiol Biotechnol	10.1007/s00253-004-1856-3	2005
Phylogeny	Pyrosequencing of a recA gene variable region for Burkholderia cepacia complex genomovar identification.	Slinger R, Yan L, Myers R, Ramotar K, St Denis M, Aaron SD.	Diagn Microbiol Infect Dis	10.1016/j.diagmicrobio.2007.02.011	2007
Pathogenicity	Antimicrobial Activity of Ibuprofen against Cystic Fibrosis-Associated Gram-Negative Pathogens.	Shah PN, Marshall-Batty KR, Smolen JA, Tagaev JA, Chen Q, Rodesney CA, Le HH, Gordon VD, Greenberg DE, Cannon CL.	Antimicrob Agents Chemother	10.1128/aac.01574-17	2018
Metabolism	Neutrophil count in sputum is associated with increased sputum glucose and sputum L-lactate in cystic fibrosis.	Nielsen BU, Kolpen M, Jensen PO, Katzenstein T, Pressler T, Ritz C, Mathiesen IHM, Faurholt-Jepsen D.	PLoS One	10.1371/journal.pone.0238524	2020
	Siderophores promote cooperative interspecies and intraspecies cross-protection against antibiotics in vitro.	Galdino ACM, Vaillancourt M, Celedonio D, Huse K, Doi Y, Lee JS, Jorth P.	Nat Microbiol	10.1038/s41564-024-01601-4	2024
	Diversity and Mechanisms of Action of Plant, Animal, and Human Antimicrobial Peptides.	Satchanska G, Davidova S, Gergova A.	Antibiotics (Basel)	10.3390/antibiotics13030202	2024
	A Microbial World: Could Metagenomic Next-Generation Sequencing Be Involved in Acute Respiratory Failure?	Huang C, Chen H, Ding Y, Ma X, Zhu H, Zhang S, Du W, Summah HD, Shi G, Feng Y.	Front Cell Infect Microbiol	10.3389/fcimb.2021.738074	2021
	Bacterial biofilms predominate in both acute and chronic human lung infections.	Kolpen M, Kragh KN, Enciso JB, Faurholt-Jepsen D, Lindegaard B, Egelund GB, Jensen AV, Ravn P, Mathiesen IHM, Gheorge AG, Hertz FB, Qvist T, Whiteley M, Jensen PO, Bjarnsholt T.	Thorax	10.1136/thoraxjnl-2021-217576	2022
Metabolism	Microbial diversity and functional genes of red vinasse acid based on metagenome analysis.	Lv J, Ye Y, Zhong Y, Liu W, Chen M, Guo A, Lv J, Ma H.	Front Microbiol	10.3389/fmicb.2022.1025886	2022
Pathogenicity	Resistance of planktonic and biofilm-grown Burkholderia cepacia complex isolates to the transition metal gallium.	Peeters E, Nelis HJ, Coenye T.	J Antimicrob Chemother	10.1093/jac/dkn072	2008
	Novel sterol binding domains in bacteria.	Zhai L, Bonds AC, Smith CA, Oo H, Chou JC, Welander PV, Dassama LMK.	Elife	10.7554/elife.90696	2024
Phylogeny	Accurate and rapid identification of the Burkholderia pseudomallei near-neighbour, Burkholderia ubonensis, using real-time PCR.	Price EP, Sarovich DS, Webb JR, Ginther JL, Mayo M, Cook JM, Seymour ML, Kaestli M, Theobald V, Hall CM, Busch JD, Foster JT, Keim P, Wagner DM, Tuanyok A, Pearson T, Currie BJ.	PLoS One	10.1371/journal.pone.0071647	2013
	Identification of host-immune response protein candidates in the sera of human oral squamous cell carcinoma patients.	Chen Y, Azman SN, Kerishnan JP, Zain RB, Chen YN, Wong YL, Gopinath SC.	PLoS One	10.1371/journal.pone.0109012	2014
	Comparative genomics of Burkholderia multivorans, a ubiquitous pathogen with a highly conserved genomic structure.	Peeters C, Cooper VS, Hatcher PJ, Verheyde B, Carlier A, Vandamme P.	PLoS One	10.1371/journal.pone.0176191	2017
	In Silico Characterization of a Hypothetical Protein from Shigella dysenteriae ATCC 12039 Reveals a Pathogenesis-Related Protein of the Type-VI Secretion System.	Rabbi MF, Akter SA, Hasan MJ, Amin A.	Bioinform Biol Insights	10.1177/11779322211011140	2021
	Burkholderia cepacia complex bacteria: opportunistic pathogens with important natural biology.	Mahenthiralingam E, Baldwin A, Dowson CG.	J Appl Microbiol	10.1111/j.1365-2672.2007.03706.x	2008
Pathogenicity	Overcoming an Extremely Drug Resistant (XDR) Pathogen: Avibactam Restores Susceptibility to Ceftazidime for Burkholderia cepacia Complex Isolates from Cystic Fibrosis Patients.	Papp-Wallace KM, Becka SA, Zeiser ET, Ohuchi N, Mojica MF, Gatta JA, Falleni M, Tosi D, Borghi E, Winkler ML, Wilson BM, LiPuma JJ, Nukaga M, Bonomo RA.	ACS Infect Dis	10.1021/acsinfecdis.7b00020	2017
Pathogenicity	Long-Term Evolution of Burkholderia multivorans during a Chronic Cystic Fibrosis Infection Reveals Shifting Forces of Selection.	Silva IN, Santos PM, Santos MR, Zlosnik JE, Speert DP, Buskirk SW, Bruger EL, Waters CM, Cooper VS, Moreira LM.	mSystems	10.1128/msystems.00029-16	2016
Metabolism	The Cystic Fibrosis-Like Airway Surface Layer Is not a Significant Barrier for Delivery of Eluforsen to Airway Epithelial Cells.	Brinks V, Lipinska K, de Jager M, Beumer W, Button B, Livraghi-Butrico A, Henig N, Matthee B.	J Aerosol Med Pulm Drug Deliv	10.1089/jamp.2018.1502	2019
	Structural analysis of resistance-nodulation cell division transporters.	Klenotic PA, Yu EW.	Microbiol Mol Biol Rev	10.1128/mmbr.00198-23	2024
	A German external quality survey of diagnostic microbiology of respiratory tract infections in patients with cystic fibrosis.	Balke B, Schmoldt S, Haussler S, Suerbaum S, Heesemann J, Hogardt M.	J Cyst Fibros	10.1016/j.jcf.2007.02.007	2008
Enzymology	[Isolation and identification of Burkholderia cepacia complex from cystic fibrosis patients].	Yurdakul P, Ergunay K, Yalcin E, Dogru D, Sener B, Cobanoglu N, Ozcelik U, Kiper N.	Mikrobiyol Bul		2006
	Factors Associated With MALDI-TOF Mass Spectral Quality of Species Identification in Clinical Routine Diagnostics.	Cuenod A, Foucault F, Pfluger V, Egli A.	Front Cell Infect Microbiol	10.3389/fcimb.2021.646648	2021
	Evidence of transmission of Burkholderia cepacia, Burkholderia multivorans and Burkholderia dolosa among persons with cystic fibrosis.	Biddick R, Spilker T, Martin A, LiPuma JJ.	FEMS Microbiol Lett	10.1016/s0378-1097(03)00724-9	2003
	A new mini-transposon for in vivo protein epitope tagging: application to Burkholderia multivorans.	Kholti A, Plesa M, Cornelis P.	Res Microbiol	10.1016/s0923-2508(03)00080-9	2003
	Transcriptomic Response of the Diazotrophic Bacteria Gluconacetobacter diazotrophicus Strain PAL5 to Iron Limitation and Characterization of the fur Regulatory Network.	Soares CP, Trada-Sfeir MZ, Terra LA, Ferreira JP, Dos-Santos CM, Oliveira IGB, Araujo JLS, Meneses CHSG, de Souza EM, Baldani JI, Vidal MS.	Int J Mol Sci	10.3390/ijms23158533	2022
Pathogenicity	The effect of recombinant human lactoferrin on growth and the antibiotic susceptibility of the cystic fibrosis pathogen Burkholderia cepacia complex when cultured planktonically or as biofilms.	Caraher EM, Gumulapurapu K, Taggart CC, Murphy P, McClean S, Callaghan M.	J Antimicrob Chemother	10.1093/jac/dkm222	2007
	Genome-Wide Analysis of Sugar Transporters Identifies the gtsA Gene for Glucose Transportation in Pseudomonas stutzeri A1501.	Liu Y, Shang L, Zhan Y, Lin M, Liu Z, Yan Y.	Microorganisms	10.3390/microorganisms8040592	2020
Genetics	Hospital sink traps as a potential source of the emerging multidrug-resistant pathogen Cupriavidus pauculus: characterization and draft genome sequence of strain MF1.	Butler J, Kelly SD, Muddiman KJ, Besinis A, Upton M.	J Med Microbiol	10.1099/jmm.0.001501	2022
	Lung Ultrasound in the Evaluation of Lung Disease Severity in Children with Clinically Stable Cystic Fibrosis: A Prospective Cross-Sectional Study.	Jaworska J, Buda N, Kwasniewicz P, Komorowska-Piotrowska A, Sands D.	J Clin Med	10.3390/jcm12093086	2023
	Lung transplant referral practice patterns: a survey of cystic fibrosis physicians and general pulmonologists.	Bartley BL, Schwartz CE, Stark RB, Georgiopoulos AM, Friedman D, Richards CJ, Dorkin HL, Kinane TB, Neuringer IP, Yonker LM.	BMC Pulm Med	10.1186/s12890-020-1067-4	2020
	Noninvasive Combined Diagnosis and Monitoring of Aspergillus and Pseudomonas Infections: Proof of Concept.	Dobias R, Skriba A, Pluhacek T, Petrik M, Palyzova A, Kanova M, Cubova E, Houst J, Novak J, Stevens DA, Mitulovic G, Krejci E, Hubacek P, Havlicek V.	J Fungi (Basel)	10.3390/jof7090730	2021
	Bacterial evolution during human infection: Adapt and live or adapt and die.	Culyba MJ, Van Tyne D.	PLoS Pathog	10.1371/journal.ppat.1009872	2021
Metabolism	Characterization of N-acyl homoserine lactone overproducing mutants of Burkholderia multivorans ATCC 17616.	Yao F, Zhou H, Lessie TG.	FEMS Microbiol Lett	10.1111/j.1574-6968.2002.tb11010.x	2002
Metabolism	Highly purified lipopolysaccharides from Burkholderia cepacia complex clinical isolates induce inflammatory cytokine responses via TLR4-mediated MAPK signalling pathways and activation of NFkappaB.	Bamford S, Ryley H, Jackson SK.	Cell Microbiol	10.1111/j.1462-5822.2006.00808.x	2007
	Artificial organelles for sustainable chemical energy conversion and production in artificial cells: Artificial mitochondrion and chloroplasts.	Park H, Wang W, Min SH, Ren Y, Shin K, Han X.	Biophys Rev (Melville)	10.1063/5.0131071	2023
	Identification of Burkholderia cepacia complex pathogens by rapid-cycle PCR with fluorescent hybridization probes.	Vonberg RP, Haussler S, Vandamme P, Steinmetz I.	J Med Microbiol	10.1099/jmm.0.46457-0	2006
Metabolism	Exopolysaccharides produced by clinical strains belonging to the Burkholderia cepacia complex.	Herasimenka Y, Cescutti P, Impallomeni G, Campana S, Taccetti G, Ravenni N, Zanetti F, Rizzo R.	J Cyst Fibros	10.1016/j.jcf.2006.06.004	2007
	Characterization of Burkholderia pseudomallei from spontaneous melioidosis in a Bornean orangutan.	Testamenti VA, Surya M, Saepuloh U, Iskandriati D, Tandang MV, Kristina L, Wahyudi AT, Sajuthi D, Santi VD, Patispathika FH, Wahyu M, Nurcahyo A, Pamungkas J.	Vet World	10.14202/vetworld.2020.2459-2468	2020
Enzymology	Evaluation of Various Culture Media for Detection of Rapidly Growing Mycobacteria from Patients with Cystic Fibrosis.	Preece CL, Wichelhaus TA, Perry A, Jones AL, Cummings SP, Perry JD, Hogardt M.	J Clin Microbiol	10.1128/jcm.00471-16	2016
	Update on the Burkholderia cepacia complex.	Lipuma JJ.	Curr Opin Pulm Med	10.1097/01.mcp.0000181475.85187.ed	2005
	RNA-seq reveals multifaceted gene expression response to Fab production in Escherichia coli fed-batch processes with particular focus on ribosome stalling.	Vazulka S, Schiavinato M, Tauer C, Wagenknecht M, Cserjan-Puschmann M, Striedner G.	Microb Cell Fact	10.1186/s12934-023-02278-w	2024
Pathogenicity	In vitro activity of N-acetylcysteine against Stenotrophomonas maltophilia and Burkholderia cepacia complex grown in planktonic phase and biofilm.	Pollini S, Di Pilato V, Landini G, Di Maggio T, Cannatelli A, Sottotetti S, Cariani L, Aliberti S, Blasi F, Sergio F, Rossolini GM, Pallecchi L.	PLoS One	10.1371/journal.pone.0203941	2018
	[Use of 16S rRNA gene sequencing for identification of "Pseudomonas-like" isolates from sputum of patients with cystic fibrosis].	Moissenet D, Bingen E, Arlet G, Vu-Thien H.	Pathol Biol (Paris)	10.1016/j.patbio.2005.06.004	2005
	Queuosine biosynthetic enzyme, QueE moonlights as a cell division regulator.	Adeleye SA, Yadavalli SS.	PLoS Genet	10.1371/journal.pgen.1011287	2024
	Antibiotic therapy for chronic infection with Burkholderia cepacia complex in people with cystic fibrosis.	Frost F, Shaw M, Nazareth D.	Cochrane Database Syst Rev	10.1002/14651858.cd013079.pub2	2019
	Distribution and genomic location of active insertion sequences in the Burkholderia cepacia complex.	Kenna DT, Yesilkaya H, Forbes KJ, Barcus VA, Vandamme P, Govan JRW.	J Med Microbiol	10.1099/jmm.0.46175-0	2006
	Bacterial behavior in human blood reveals complement evaders with some persister-like features.	Pont S, Fraikin N, Caspar Y, Van Melderen L, Attree I, Cretin F.	PLoS Pathog	10.1371/journal.ppat.1008893	2020
	The nematode Panagrellus redivivus is susceptible to killing by human pathogens at 37 degrees C.	Laws TR, Smith SA, Smith MP, Harding SV, Atkins TP, Titball RW.	FEMS Microbiol Lett	10.1016/j.femsle.2005.06.046	2005
Metabolism	Burkholderia contaminans Biofilm Regulating Operon and Its Distribution in Bacterial Genomes.	Voronina OL, Kunda MS, Ryzhova NN, Aksenova EI, Semenov AN, Romanova YM, Gintsburg AL.	Biomed Res Int	10.1155/2016/6560534	2016
	Bed bugs and possible transmission of human pathogens: a systematic review.	Lai O, Ho D, Glick S, Jagdeo J.	Arch Dermatol Res	10.1007/s00403-016-1661-8	2016
	Metagenomic Next-Generation Sequencing of Cerebrospinal Fluid for the Diagnosis of External Ventricular and Lumbar Drainage-Associated Ventriculitis and Meningitis.	Qian L, Shi Y, Li F, Wang Y, Ma M, Zhang Y, Shao YW, Zheng G, Zhang G.	Front Microbiol	10.3389/fmicb.2020.596175	2020
Enzymology	Impact of clonally-related Burkholderia contaminans strains in two patients attending an Italian cystic fibrosis centre: a case report.	Savi D, Quattrucci S, Trancassini M, Dalmastri C, De Biase RV, Maggisano M, Palange P, Bevivino A.	BMC Pulm Med	10.1186/s12890-019-0923-6	2019
Phylogeny	Identification of potential diagnostic markers among Burkholderia cenocepacia and B. multivorans supernatants.	Mott T, Soler M, Grigsby S, Medley R, Whitlock GC.	J Clin Microbiol	10.1128/jcm.00577-10	2010
Genetics	MetaPalette: a k-mer Painting Approach for Metagenomic Taxonomic Profiling and Quantification of Novel Strain Variation.	Koslicki D, Falush D.	mSystems	10.1128/msystems.00020-16	2016
Enzymology	Matrix-assisted laser desorption/ionization time-of-flight MS for the accurate identification of Burkholderia cepacia complex and Burkholderia gladioli in the clinical microbiology laboratory.	Wong KSK, Dhaliwal S, Bilawka J, Srigley JA, Champagne S, Romney MG, Tilley P, Sadarangani M, Zlosnik JEA, Chilvers MA.	J Med Microbiol	10.1099/jmm.0.001223	2020
	Improved flagellin genotyping in the Burkholderia cepacia complex.	Winstanley C.	FEMS Microbiol Lett	10.1016/s0378-1097(03)00721-3	2003
	Antibiofilm and anti-quorum sensing activities of polyethylene imine coated magnetite and nickel ferrite nanoparticles.	Ceylan O, Tamfu AN, Dogac YI, Teke M.	3 Biotech	10.1007/s13205-020-02509-6	2020
	Environmental Factors Associated With Soil Prevalence of the Melioidosis Pathogen Burkholderia pseudomallei: A Longitudinal Seasonal Study From South West India.	Shaw T, Assig K, Tellapragada C, Wagner GE, Choudhary M, Gohler A, Eshwara VK, Steinmetz I, Mukhopadhyay C.	Front Microbiol	10.3389/fmicb.2022.902996	2022
Pathogenicity	Laser-induced vapour nanobubbles improve drug diffusion and efficiency in bacterial biofilms.	Teirlinck E, Xiong R, Brans T, Forier K, Fraire J, Van Acker H, Matthijs N, De Rycke R, De Smedt SC, Coenye T, Braeckmans K.	Nat Commun	10.1038/s41467-018-06884-w	2018
	Effects of gut microbiota remodeling on the dysbiosis induced by high fat diet in a mouse model of Gulf war illness.	Angoa-Perez M, Zagorac B, Francescutti DM, Theis KR, Kuhn DM.	Life Sci	10.1016/j.lfs.2021.119675	2021
Genetics	Probe design for simultaneous, targeted capture of diverse metagenomic targets.	Dickson ZW, Hackenberger D, Kuch M, Marzok A, Banerjee A, Rossi L, Klowak JA, Fox-Robichaud A, Mossmann K, Miller MS, Surette MG, Golding GB, Poinar H.	Cell Rep Methods	10.1016/j.crmeth.2021.100069	2021
Enzymology	Molecular characterization of Wolbachia infection in bed bugs (Cimex lectularius) collected from several localities in France.	Akhoundi M, Cannet A, Loubatier C, Berenger JM, Izri A, Marty P, Delaunay P.	Parasite	10.1051/parasite/2016031	2016
Enzymology	Epidemiology of Burkholderia cepacia complex colonisation in cystic fibrosis patients.	De Boeck K, Malfroot A, Van Schil L, Lebecque P, Knoop C, Govan JR, Doherty C, Laevens S, Vandamme P, Belgian Burkholderia cepacia Study Group.	Eur Respir J	10.1183/09031936.04.00118804	2004
	Mycobacterium abscessus phospholipase C expression is induced during coculture within amoebae and enhances M. abscessus virulence in mice.	Bakala N'Goma JC, Le Moigne V, Soismier N, Laencina L, Le Chevalier F, Roux AL, Poncin I, Serveau-Avesque C, Rottman M, Gaillard JL, Etienne G, Brosch R, Herrmann JL, Canaan S, Girard-Misguich F.	Infect Immun	10.1128/iai.02032-14	2015
Pathogenicity	Antibacterial effects of knotwood extractives on paper mill bacteria.	Lindberg LE, Willfor SM, Holmbom BR.	J Ind Microbiol Biotechnol	10.1007/s10295-004-0132-y	2004
Enzymology	Regulator LdhR and d-Lactate Dehydrogenase LdhA of Burkholderia multivorans Play Roles in Carbon Overflow and in Planktonic Cellular Aggregate Formation.	Silva IN, Ramires MJ, Azevedo LA, Guerreiro AR, Tavares AC, Becker JD, Moreira LM.	Appl Environ Microbiol	10.1128/aem.01343-17	2017
Pathogenicity	Virulence and cellular interactions of Burkholderia multivorans in chronic granulomatous disease.	Zelazny AM, Ding L, Elloumi HZ, Brinster LR, Benedetti F, Czapiga M, Ulrich RL, Ballentine SJ, Goldberg JB, Sampaio EP, Holland SM.	Infect Immun	10.1128/iai.00259-09	2009
	Chronic Burkholderia multivorans bronchial infection in a non-cystic fibrosis individual with mannose binding lectin deficiency.	Whitehouse JL, Exley AR, Foweraker J, Bilton D.	Thorax	10.1136/thx.2003.016493	2005
Enzymology	Genomovar diversity amongst Burkholderia cepacia complex isolates from an Australian adult cystic fibrosis unit.	Kidd TJ, Bell SC, Coulter C.	Eur J Clin Microbiol Infect Dis	10.1007/s10096-003-0949-8	2003
Metabolism	Burkholderia cepacia Complex Species Differ in the Frequency of Variation of the Lipopolysaccharide O-Antigen Expression During Cystic Fibrosis Chronic Respiratory Infection.	Hassan AA, Coutinho CP, Sa-Correia I.	Front Cell Infect Microbiol	10.3389/fcimb.2019.00273	2019
Metabolism	Staphylococcus aureus Genomes Harbor Only MpsAB-Like Bicarbonate Transporter but Not Carbonic Anhydrase as Dissolved Inorganic Carbon Supply System.	Fan SH, Liberini E, Gotz F.	Microbiol Spectr	10.1128/spectrum.00970-21	2021
Phylogeny	Niche Differentiation of Arsenic-Transforming Microbial Groups in the Rice Rhizosphere Compartments as Impacted by Water Management and Soil-Arsenic Concentrations.	Somenahally AC, Loeppert RH, Zhou J, Gentry TJ.	Front Microbiol	10.3389/fmicb.2021.736751	2021
	Infection with Burkholderia cepacia complex genomovars in patients with cystic fibrosis: virulent transmissible strains of genomovar III can replace Burkholderia multivorans.	Mahenthiralingam E, Vandamme P, Campbell ME, Henry DA, Gravelle AM, Wong LT, Davidson AG, Wilcox PG, Nakielna B, Speert DP.	Clin Infect Dis	10.1086/322684	2001
	Improved molecular detection of Burkholderia cepacia genomovar III and Burkholderia multivorans directly from sputum of patients with cystic fibrosis.	Moore JE, Xu J, Millar BC, Crowe M, Elborn JS.	J Microbiol Methods	10.1016/s0167-7012(01)00367-0	2002
	Clinical outcome of Burkholderia cepacia complex infection in cystic fibrosis adults.	Courtney JM, Dunbar KE, McDowell A, Moore JE, Warke TJ, Stevenson M, Elborn JS.	J Cyst Fibros	10.1016/j.jcf.2004.01.005	2004
	Widespread fungal-bacterial competition for magnesium lowers bacterial susceptibility to polymyxin antibiotics.	Hsieh YP, Sun W, Young JM, Cheung R, Hogan DA, Dandekar AA, Malik HS.	PLoS Biol	10.1371/journal.pbio.3002694	2024
	Computational engineering of previously crystallized pyruvate formate-lyase activating enzyme reveals insights into SAM binding and reductive cleavage.	Moody JD, Hill S, Lundahl MN, Saxton AJ, Galambas A, Broderick WE, Lawrence CM, Broderick JB.	J Biol Chem	10.1016/j.jbc.2023.104791	2023
Genetics	Complete genome sequencing of Pandoraea pnomenusa RB38 and Molecular Characterization of Its N-acyl homoserine lactone synthase gene ppnI.	Lim YL, Ee R, How KY, Lee SK, Yong D, Tee KK, Yin WF, Chan KG.	PeerJ	10.7717/peerj.1225	2015
	Role of Efflux in Antibiotic Resistance of Achromobacter xylosoxidans and Achromobacter insuavis Isolates From Patients With Cystic Fibrosis.	Chalhoub H, Kampmeier S, Kahl BC, Van Bambeke F.	Front Microbiol	10.3389/fmicb.2022.762307	2022
Genetics	Mock community taxonomic classification performance of publicly available shotgun metagenomics pipelines.	Valencia EM, Maki KA, Dootz JN, Barb JJ.	Sci Data	10.1038/s41597-023-02877-7	2024
	Identification of Burkholderia cenocepacia non-coding RNAs expressed during Caenorhabditis elegans infection.	Pita T, Feliciano JR, Leitao JH.	Appl Microbiol Biotechnol	10.1007/s00253-023-12530-3	2023
Phylogeny	Fatal outcome of lung transplantation in cystic fibrosis patients due to small-colony variants of the Burkholderia cepacia complex.	Haussler S, Lehmann C, Breselge C, Rohde M, Classen M, Tummler B, Vandamme P, Steinmetz I.	Eur J Clin Microbiol Infect Dis	10.1007/s10096-003-0901-y	2003
	Identification of Novel PhoP-PhoQ Regulated Genes That Contribute to Polymyxin B Tolerance in Pseudomonas aeruginosa.	Yang B, Liu C, Pan X, Fu W, Fan Z, Jin Y, Bai F, Cheng Z, Wu W.	Microorganisms	10.3390/microorganisms9020344	2021
	Colloidal silver for lung disease in cystic fibrosis.	Baral VR, Dewar AL, Connett GJ.	J R Soc Med	10.1258/jrsm.2008.s18012	2008
Phylogeny	Lack of correlation between O-serotype, bacteriophage susceptibility and genomovar status in the Burkholderia cepacia complex.	Kenna DT, Barcus VA, Langley RJ, Vandamme P, Govan JR.	FEMS Immunol Med Microbiol	10.1016/s0928-8244(02)00442-x	2003
	Long-term outcome of lung transplantation for cystic fibrosis--Danish results.	Bech B, Pressler T, Iversen M, Carlsen J, Milman N, Eliasen K, Perko M, Arendrup H.	Eur J Cardiothorac Surg	10.1016/j.ejcts.2004.08.015	2004
Enzymology	Epidemiology of Burkholderia cepacia complex species recovered from cystic fibrosis patients: issues related to patient segregation.	McDowell A, Mahenthiralingam E, Dunbar KEA, Moore JE, Crowe M, Elborn JS.	J Med Microbiol	10.1099/jmm.0.45557-0	2004
Metabolism	Creatine utilization as a sole nitrogen source in Pseudomonas putida KT2440 is transcriptionally regulated by CahR.	Hinkel LA, Willsey GG, Lenahan SM, Eckstrom K, Schutz KC, Wargo MJ.	Microbiology (Reading)	10.1099/mic.0.001145	2022
	Construction of a synthetic metabolic pathway for biosynthesis of 2,4-dihydroxybutyric acid from ethylene glycol.	Frazao CJR, Wagner N, Rabe K, Walther T.	Nat Commun	10.1038/s41467-023-37558-x	2023
Pathogenicity	In vitro activity and synergy of bismuth thiols and tobramycin against Burkholderia cepacia complex.	Veloira WG, Domenico P, LiPuma JJ, Davis JM, Gurzenda E, Kazzaz JA.	J Antimicrob Chemother	10.1093/jac/dkg471	2003
Enzymology	A Novel Solid Medium for Culturing Mycobacterium tuberculosis Isolates from Clinical Specimens.	Asmar S, Chatellier S, Mirande C, van Belkum A, Canard I, Raoult D, Drancourt M.	J Clin Microbiol	10.1128/jcm.01149-15	2015
Phylogeny	DNA-DNA hybridization study of Burkholderia species using genomic DNA macro-array analysis coupled to reverse genome probing.	Ramisse V, Balandreau J, Thibault F, Vidal D, Vergnaud G, Normand P.	Int J Syst Evol Microbiol	10.1099/ijs.0.02483-0	2003
Phylogeny	Evaluation of restriction fragment length polymorphism analysis of 16S rDNA as a tool for genomovar characterisation within the Burkholderia cepacia complex.	Vermis K, Vandekerckhove C, Nelis HJ, Vandamme PA.	FEMS Microbiol Lett	10.1111/j.1574-6968.2002.tb11316.x	2002
	Practical Guidance for Clinical Microbiology Laboratories: Updated guidance for processing respiratory tract samples from people with cystic fibrosis.	Saiman L, Waters V, LiPuma JJ, Hoffman LR, Alby K, Zhang SX, Yau YC, Downey DG, Sermet-Gaudelus I, Bouchara J-P, Kidd TJ, Bell SC, Brown AW.	Clin Microbiol Rev	10.1128/cmr.00215-21	2024
Enzymology	Mangrove endophyte promotes reforestation tree (Acacia polyphylla) growth.	Castro RA, Dourado MN, Almeida JR, Lacava PT, Nave A, Melo IS, Azevedo JL, Quecine MC.	Braz J Microbiol	10.1016/j.bjm.2017.04.002	2018
Phylogeny	Genomic analysis and relatedness of P2-like phages of the Burkholderia cepacia complex.	Lynch KH, Stothard P, Dennis JJ, Dennis JJ.	BMC Genomics	10.1186/1471-2164-11-599	2010
	Phage Therapy in Germany-Update 2023.	Willy C, Bugert JJ, Classen AY, Deng L, Duchting A, Gross J, Hammerl JA, Korf IHE, Kuhn C, Lieberknecht-Jouy S, Rohde C, Rupp M, Vehreschild MJGT, Vogele K, Wienecke S, Witzenrath M, Wurstle S, Ziehr H, Moelling K, Broecker F.	Viruses	10.3390/v15020588	2023
	Suppression-subtractive hybridisation reveals variations in gene distribution amongst the Burkholderia cepacia complex, including the presence in some strains of a genomic island containing putative polysaccharide production genes.	Parsons YN, Banasko R, Detsika MG, Duangsonk K, Rainbow L, Hart CA, Winstanley C.	Arch Microbiol	10.1007/s00203-003-0518-7	2003
Phylogeny	Unusual distribution of Burkholderia cepacia complex species in Danish cystic fibrosis clinics may stem from restricted transmission between patients.	Norskov-Lauritsen N, Johansen HK, Fenger MG, Nielsen XC, Pressler T, Olesen HV, Hoiby N.	J Clin Microbiol	10.1128/jcm.00383-10	2010
Pathogenicity	Fosmidomycin decreases membrane hopanoids and potentiates the effects of colistin on Burkholderia multivorans clinical isolates.	Malott RJ, Wu CH, Lee TD, Hird TJ, Dalleska NF, Zlosnik JE, Newman DK, Speert DP.	Antimicrob Agents Chemother	10.1128/aac.02705-14	2014
	The Regulatory Protein ChuP Connects Heme and Siderophore-Mediated Iron Acquisition Systems Required for Chromobacterium violaceum Virulence.	de Lima VM, Batista BB, da Silva Neto JF.	Front Cell Infect Microbiol	10.3389/fcimb.2022.873536	2022
Genetics	Proteogenomic Analysis of Burkholderia Species Strains 25 and 46 Isolated from Uraniferous Soils Reveals Multiple Mechanisms to Cope with Uranium Stress.	Agarwal M, Pathak A, Rathore RS, Prakash O, Singh R, Jaswal R, Seaman J, Chauhan A.	Cells	10.3390/cells7120269	2018
	Antimicrobial Efficacy of Indolicidin Against Multi-Drug Resistant Enteroaggregative Escherichia coli in a Galleria mellonella Model.	Vergis J, Malik SS, Pathak R, Kumar M, Ramanjaneya S, Kurkure NV, Barbuddhe SB, Rawool DB.	Front Microbiol	10.3389/fmicb.2019.02723	2019
	Functional quorum sensing systems are maintained during chronic Burkholderia cepacia complex infections in patients with cystic fibrosis.	McKeon SA, Nguyen DT, Viteri DF, Zlosnik JE, Sokol PA.	J Infect Dis	10.1093/infdis/jiq054	2011
Genetics	South Africa's indigenous microbial diversity for industrial applications: A review of the current status and opportunities.	Chhiba V, Pillay P, Mtimka S, Moonsamy G, Kwezi L, Pooe OJ, Tsekoa TL.	Heliyon	10.1016/j.heliyon.2023.e16723	2023
	Cryo-EM structure of the Hedgehog release protein Dispatched.	Cannac F, Qi C, Falschlunger J, Hausmann G, Basler K, Korkhov VM.	Sci Adv	10.1126/sciadv.aay7928	2020
	[Burkholderia cepacia: dangers of a phytopathogen organism for patients with cystic fibrosis].	Segonds C, Chabanon G.	Ann Biol Clin (Paris)		2001
Metabolism	Characterization of the poly-beta-1,6-N-acetylglucosamine polysaccharide component of Burkholderia biofilms.	Yakandawala N, Gawande PV, LoVetri K, Cardona ST, Romeo T, Nitz M, Madhyastha S.	Appl Environ Microbiol	10.1128/aem.05814-11	2011
Pathogenicity	Targeting the Nonmevalonate Pathway in Burkholderia cenocepacia Increases Susceptibility to Certain beta-Lactam Antibiotics.	Sass A, Everaert A, Van Acker H, Van den Driessche F, Coenye T.	Antimicrob Agents Chemother	10.1128/aac.02607-17	2018
Phylogeny	Elucidating global epidemiology of Burkholderia multivorans in cases of cystic fibrosis by multilocus sequence typing.	Baldwin A, Mahenthiralingam E, Drevinek P, Pope C, Waine DJ, Henry DA, Speert DP, Carter P, Vandamme P, LiPuma JJ, Dowson CG.	J Clin Microbiol	10.1128/jcm.01818-07	2008
	Phenolic acid-degrading Paraburkholderia prime decomposition in forest soil.	Wilhelm RC, DeRito CM, Shapleigh JP, Madsen EL, Buckley DH.	ISME Commun	10.1038/s43705-021-00009-z	2021
Metabolism	Biosynthesis of Ditropolonyl Sulfide, an Antibacterial Compound Produced by Burkholderia cepacia Complex Strain R-12632.	Depoorter E, Coenye T, Vandamme P.	Appl Environ Microbiol	10.1128/aem.01169-21	2021
Pathogenicity	Conjugation to Enterobactin and Salmochelin S4 Enhances the Antimicrobial Activity and Selectivity of beta-Lactam Antibiotics against Nontyphoidal Salmonella.	Sargun A, Sassone-Corsi M, Zheng T, Raffatellu M, Nolan EM.	ACS Infect Dis	10.1021/acsinfecdis.1c00005	2021
	Molecular, physiological, and biochemical characterization of extracellular lipase production by Aspergillus niger using submerged fermentation.	Alabdalall AH, ALanazi NA, A Aldakeel S, AbdulAzeez S, Borgio JF.	PeerJ	10.7717/peerj.9425	2020
Pathogenicity	Resurrecting Old beta-Lactams: Potent Inhibitory Activity of Temocillin against Multidrug-Resistant Burkholderia Species Isolates from the United States.	Zeiser ET, Becka SA, Barnes MD, Taracila MA, LiPuma JJ, Papp-Wallace KM.	Antimicrob Agents Chemother	10.1128/aac.02315-18	2019
	A New Antisense Phosphoryl Guanidine Oligo-2'-O-Methylribonucleotide Penetrates Into Intracellular Mycobacteria and Suppresses Target Gene Expression.	Skvortsova YV, Salina EG, Burakova EA, Bychenko OS, Stetsenko DA, Azhikina TL.	Front Pharmacol	10.3389/fphar.2019.01049	2019
	In Vitro Antibacterial Activity and In Vivo Efficacy of Sulbactam-Durlobactam against Pathogenic Burkholderia Species.	Papp-Wallace KM, Shapiro AB, Becka SA, Zeiser ET, LiPuma JJ, Lane DJ, Panchal RG, Mueller JP, O'Donnell JP, Miller AA.	Antimicrob Agents Chemother	10.1128/aac.01930-20	2021
	Ceftazidime-Avibactam for the Treatment of Serious Gram-Negative Infections with Limited Treatment Options: A Systematic Literature Review.	Soriano A, Carmeli Y, Omrani AS, Moore LSP, Tawadrous M, Irani P.	Infect Dis Ther	10.1007/s40121-021-00507-6	2021
Enzymology	Lack of influence by endosymbiont Wolbachia on virus titer in the common bed bug, Cimex lectularius.	Fisher ML, Levine JF, Guy JS, Mochizuki H, Breen M, Schal C, Watson DW.	Parasit Vectors	10.1186/s13071-019-3694-2	2019
Phylogeny	Burkholderia cepacia genomovar VI, a new member of the Burkholderia cepacia complex isolated from cystic fibrosis patients.	Coenye T, LiPuma JJ, Henry D, Hoste B, Vandemeulebroecke K, Gillis M, Speert DP, Vandamme P.	Int J Syst Evol Microbiol	10.1099/00207713-51-2-271	2001
Transcriptome	The Lymantria dispar IPLB-Ld652Y cell line transcriptome comprises diverse virus-associated transcripts.	Sparks ME, Gundersen-Rindal DE.	Viruses	10.3390/v3112339	2011
Enzymology	A Radical Intermediate in Bacillus subtilis QueE during Turnover with the Substrate Analogue 6-Carboxypterin.	Wilcoxen J, Bruender NA, Bandarian V, Britt RD.	J Am Chem Soc	10.1021/jacs.7b10860	2018
	Role of actin filament network in Burkholderia multivorans invasion in well-differentiated human airway epithelia.	Schwab UE, Ribeiro CM, Neubauer H, Boucher RC.	Infect Immun	10.1128/iai.71.11.6607-6609.2003	2003
	Determinants of Antibacterial Spectrum and Resistance Potential of the Elongation Factor G Inhibitor Argyrin B in Key Gram-Negative Pathogens.	Jones AK, Woods AL, Takeoka KT, Shen X, Wei JR, Caughlan RE, Dean CR.	Antimicrob Agents Chemother	10.1128/aac.02400-16	2017
	Improving specificity of Bordetella pertussis detection using a four target real-time PCR.	Martini H, Detemmerman L, Soetens O, Yusuf E, Pierard D.	PLoS One	10.1371/journal.pone.0175587	2017
Phylogeny	Phenotypic and genotypic properties of Microbacterium yannicii, a recently described multidrug resistant bacterium isolated from a lung transplanted patient with cystic fibrosis in France.	Sharma P, Diene SM, Thibeaut S, Bittar F, Roux V, Gomez C, Reynaud-Gaubert M, Rolain JM.	BMC Microbiol	10.1186/1471-2180-13-97	2013
	Antibiotic treatment for Burkholderia cepacia complex in people with cystic fibrosis experiencing a pulmonary exacerbation.	Lord R, Jones AM, Horsley A.	Cochrane Database Syst Rev	10.1002/14651858.cd009529.pub4	2020
	Mapping Epitopes of a Novel Peptidoglycan Cross-Linking Enzyme Cwp22 Recognized by Human Sera Obtained from Patients with Clostridioides difficile Infection and Cord Blood.	Razim A, Pacyga K, Martirosian G, Szuba A, Gamian A, Myc A, Gorska S.	Microorganisms	10.3390/microorganisms7110565	2019
Genetics	Genomic characterization of JG068, a novel virulent podovirus active against Burkholderia cenocepacia.	Lynch KH, Abdu AH, Schobert M, Dennis JJ, Dennis JJ.	BMC Genomics	10.1186/1471-2164-14-574	2013
Genetics	Epidemiology of E. coli in Cystic Fibrosis Airways Demonstrates the Capacity for Persistent Infection but Not Patient-Patient Transmission.	Izydorczyk C, Waddell B, Edwards BD, Greysson-Wong J, Surette MG, Somayaji R, Rabin HR, Conly JM, Church DL, Parkins MD.	Front Microbiol	10.3389/fmicb.2020.00475	2020
Enzymology	Total protein extraction and 2-D gel electrophoresis methods for Burkholderia species.	Velapatino B, Zlosnik JE, Hird TJ, Speert DP.	J Vis Exp	10.3791/50730	2013
Phylogeny	Microbiota analysis optimization for human bronchoalveolar lavage fluid.	Schneeberger PHH, Prescod J, Levy L, Hwang D, Martinu T, Coburn B.	Microbiome	10.1186/s40168-019-0755-x	2019
Phylogeny	Burkholderia cepacia complex: distribution of genomovars among isolates from the maize rhizosphere in Italy.	Fiore A, Laevens S, Bevivino A, Dalmastri C, Tabacchioni S, Vandamme P, Chiarini L.	Environ Microbiol	10.1046/j.1462-2920.2001.00175.x	2001
	Bacterial defenses against a natural antibiotic promote collateral resilience to clinical antibiotics.	Meirelles LA, Perry EK, Bergkessel M, Newman DK.	PLoS Biol	10.1371/journal.pbio.3001093	2021
	Genome-wide screening of lipoproteins in Actinobacillus pleuropneumoniae identifies three antigens that confer protection against virulent challenge.	Cao Y, Gao L, Zhang L, Zhou L, Yang J, Deng L, Zhao J, Qi C, Liu J.	Sci Rep	10.1038/s41598-020-58968-7	2020
Metabolism	Discovery of an L-fucono-1,5-lactonase from cog3618 of the amidohydrolase superfamily.	Hobbs ME, Vetting M, Williams HJ, Narindoshvili T, Kebodeaux DM, Hillerich B, Seidel RD, Almo SC, Raushel FM.	Biochemistry	10.1021/bi3015554	2013
	Impact of Alkyl Polyglucosides Surfactant Lutensol GD 70 on Modification of Bacterial Cell Surface Properties.	Smulek W, Kaczorek E, Zgola-Grzeskowiak A, Cybulski Z.	Water Air Soil Pollut	10.1007/s11270-015-2327-4	2015
	Two novel clinical presentations of Burkholderia cepacia infection.	Mukhopadhyay C, Bhargava A, Ayyagari A.	J Clin Microbiol	10.1128/jcm.42.8.3904-3905.2004	2004
	Cystic fibrosis respiratory microbiota: unraveling complexity to inform clinical practice.	Caverly LJ, LiPuma JJ.	Expert Rev Respir Med	10.1080/17476348.2018.1513331	2018
	N-acetylcysteine (NAC) and Its Role in Clinical Practice Management of Cystic Fibrosis (CF): A Review.	Guerini M, Condro G, Friuli V, Maggi L, Perugini P.	Pharmaceuticals (Basel)	10.3390/ph15020217	2022
	Analysis of changes in diversity and abundance of the microbial community in a cystic fibrosis patient over a multiyear period.	Stokell JR, Gharaibeh RZ, Hamp TJ, Zapata MJ, Fodor AA, Steck TR.	J Clin Microbiol	10.1128/jcm.02555-14	2015
Pathogenicity	Diagnosis of human and canine Brucella canis infection: development and evaluation of indirect enzyme-linked immunosorbent assays using recombinant Brucella proteins.	Sanchez-Jimenez MM, de la Cuesta Zuluaga JJ, Garcia-Montoya GM, Dabral N, Alzate JF, Vemulapalli R, Olivera-Angel M.	Heliyon	10.1016/j.heliyon.2020.e04393	2020
Enzymology	Deciphering the role of recurrent FAD-dependent enzymes in bacterial phosphonate catabolism.	Zangelmi E, Ruffolo F, Dinhof T, Gerdol M, Malatesta M, Chin JP, Rivetti C, Secchi A, Pallitsch K, Peracchi A.	iScience	10.1016/j.isci.2023.108108	2023
	Gold Nanoparticles: Can They Be the Next Magic Bullet for Multidrug-Resistant Bacteria?	Okkeh M, Bloise N, Restivo E, De Vita L, Pallavicini P, Visai L.	Nanomaterials (Basel)	10.3390/nano11020312	2021
	Cepacia-like syndrome caused by Burkholderia multivorans.	Zahariadis G, Levy MH, Burns JL.	Can J Infect Dis	10.1155/2003/675159	2003
	Microbial Communities of Orange Tubercles in Accelerated Low-Water Corrosion.	Phan HC, Wade SA, Blackall LL.	Appl Environ Microbiol	10.1128/aem.00610-20	2020
Metabolism	Identification of hopanoid biosynthesis genes involved in polymyxin resistance in Burkholderia multivorans.	Malott RJ, Steen-Kinnaird BR, Lee TD, Speert DP.	Antimicrob Agents Chemother	10.1128/aac.00602-11	2012
Phylogeny	Matrix-assisted laser desorption ionization-time of flight mass spectrometry for identification of nonfermenting gram-negative bacilli isolated from cystic fibrosis patients.	Degand N, Carbonnelle E, Dauphin B, Beretti JL, Le Bourgeois M, Sermet-Gaudelus I, Segonds C, Berche P, Nassif X, Ferroni A.	J Clin Microbiol	10.1128/jcm.00569-08	2008
	Stress conditions triggering mucoid morphotype variation in Burkholderia species and effect on virulence in Galleria mellonella and biofilm formation in vitro.	Silva IN, Tavares AC, Ferreira AS, Moreira LM.	PLoS One	10.1371/journal.pone.0082522	2013
	The Burkholderia pseudomallei hmqA-G Locus Mediates Competitive Fitness against Environmental Gram-Positive Bacteria.	Mou S, Jenkins CC, Okaro U, Dhummakupt ES, Mach PM, DeShazer D.	Microbiol Spectr	10.1128/spectrum.00102-21	2021
	BPI-ANCA Provides Additional Clinical Information to Anti-Pseudomonas Serology: Results from a Cohort of 117 Swedish Cystic Fibrosis Patients.	Lindberg U, Carlsson M, Hellmark T, Segelmark M.	J Immunol Res	10.1155/2015/947934	2015
Metabolism	A general protein O-glycosylation machinery conserved in Burkholderia species improves bacterial fitness and elicits glycan immunogenicity in humans.	Fathy Mohamed Y, Scott NE, Molinaro A, Creuzenet C, Ortega X, Lertmemongkolchai G, Tunney MM, Green H, Jones AM, DeShazer D, Currie BJ, Foster LJ, Ingram R, De Castro C, Valvano MA.	J Biol Chem	10.1074/jbc.ra119.009671	2019
Pathogenicity	Burkholderia cepacia complex Phage-Antibiotic Synergy (PAS): antibiotics stimulate lytic phage activity.	Kamal F, Dennis JJ, Dennis JJ.	Appl Environ Microbiol	10.1128/aem.02850-14	2015
Metabolism	Structural Basis for Cholesterol Transport-like Activity of the Hedgehog Receptor Patched.	Zhang Y, Bulkley DP, Xin Y, Roberts KJ, Asarnow DE, Sharma A, Myers BR, Cho W, Cheng Y, Beachy PA.	Cell	10.1016/j.cell.2018.10.026	2018
	An unusual cause of granulomatous disease.	McLean-Tooke AP, Aldridge C, Gilmour K, Higgins B, Hudson M, Spickett GP.	BMC Clin Pathol	10.1186/1472-6890-7-1	2007
Pathogenicity	Comparative Evolutionary Patterns of Burkholderia cenocepacia and B. multivorans During Chronic Co-infection of a Cystic Fibrosis Patient Lung.	Hassan AA, Dos Santos SC, Cooper VS, Sa-Correia I.	Front Microbiol	10.3389/fmicb.2020.574626	2020
Metabolism	MmpL3 is a lipid transporter that binds trehalose monomycolate and phosphatidylethanolamine.	Su CC, Klenotic PA, Bolla JR, Purdy GE, Robinson CV, Yu EW.	Proc Natl Acad Sci U S A	10.1073/pnas.1901346116	2019
	Progressive unilateral lung collapse in cystic fibrosis--a therapeutic challenge.	Flight WG, Hildage J, Kevin Webb A.	J R Soc Med	10.1258/jrsm.2012.12s009	2012
Phylogeny	Evaluation of the Bruker Biotyper and Vitek MS matrix-assisted laser desorption ionization-time of flight mass spectrometry systems for identification of nonfermenting gram-negative bacilli isolated from cultures from cystic fibrosis patients.	Marko DC, Saffert RT, Cunningham SA, Hyman J, Walsh J, Arbefeville S, Howard W, Pruessner J, Safwat N, Cockerill FR, Bossler AD, Patel R, Richter SS.	J Clin Microbiol	10.1128/jcm.00330-12	2012
Metabolism	Radical SAM enzyme QueE defines a new minimal core fold and metal-dependent mechanism.	Dowling DP, Bruender NA, Young AP, McCarty RM, Bandarian V, Drennan CL.	Nat Chem Biol	10.1038/nchembio.1426	2014
Phylogeny	Development of a multiple-locus variable-number tandem-repeat typing scheme for genetic fingerprinting of Burkholderia cenocepacia and application to nationwide epidemiological analysis.	Segonds C, Thouverez M, Barthe A, Bossuet-Greif N, Tisseyre L, Plesiat P, Vergnaud G, Chabanon G, Pourcel C.	J Clin Microbiol	10.1128/jcm.02473-14	2015
Enzymology	Molecular detection of multiple emerging pathogens in sputa from cystic fibrosis patients.	Bittar F, Richet H, Dubus JC, Reynaud-Gaubert M, Stremler N, Sarles J, Raoult D, Rolain JM.	PLoS One	10.1371/journal.pone.0002908	2008
Phylogeny	Persistence of Burkholderia multivorans within the pulmonary macrophage in the murine lung.	Chu KK, MacDonald KL, Davidson DJ, Speert DP.	Infect Immun	10.1128/iai.72.10.6142-6147.2004	2004
Pathogenicity	Surface charge modulation of rifampicin-loaded PLA nanoparticles to improve antibiotic delivery in Staphylococcus aureus biofilms.	Da Costa D, Exbrayat-Heritier C, Rambaud B, Megy S, Terreux R, Verrier B, Primard C.	J Nanobiotechnology	10.1186/s12951-020-00760-w	2021
Pathogenicity	Differential roles of RND efflux pumps in antimicrobial drug resistance of sessile and planktonic Burkholderia cenocepacia cells.	Buroni S, Matthijs N, Spadaro F, Van Acker H, Scoffone VC, Pasca MR, Riccardi G, Coenye T.	Antimicrob Agents Chemother	10.1128/aac.03800-14	2014
Enzymology	Inhibition of the Clostridioides difficile Class D beta-Lactamase CDD-1 by Avibactam.	Stewart NK, Toth M, Stasyuk A, Lee M, Smith CA, Vakulenko SB.	ACS Infect Dis	10.1021/acsinfecdis.0c00714	2021
Stress	High-temperature-induced transposition of insertion elements in burkholderia multivorans ATCC 17616.	Ohtsubo Y, Genka H, Komatsu H, Nagata Y, Tsuda M.	Appl Environ Microbiol	10.1128/aem.71.4.1822-1828.2005	2005
	Burkholderia cenocepacia and Burkholderia multivorans: influence on survival in cystic fibrosis.	Jones AM, Dodd ME, Govan JR, Barcus V, Doherty CJ, Morris J, Webb AK.	Thorax	10.1136/thx.2003.017210	2004
	Cystic fibrosis, a Burkholderia cenocepacia chest wall abscess and rapid clinical deterioration.	Simmonds NJ, Gyi KM.	J R Soc Med	10.1258/jrsm.2008.s18011	2008
Metabolism	ScmR, a Global Regulator of Gene Expression, Quorum Sensing, pH Homeostasis, and Virulence in Burkholderia thailandensis.	Le Guillouzer S, Groleau MC, Mauffrey F, Deziel E.	J Bacteriol	10.1128/jb.00776-19	2020
Phylogeny	Species distribution and ribotype diversity of Burkholderia cepacia complex isolates from French patients with cystic fibrosis.	Brisse S, Cordevant C, Vandamme P, Bidet P, Loukil C, Chabanon G, Lange M, Bingen E.	J Clin Microbiol	10.1128/jcm.42.10.4824-4827.2004	2004
Pathogenicity	Potent modulation of the CepR quorum sensing receptor and virulence in a Burkholderia cepacia complex member using non-native lactone ligands.	Slinger BL, Deay JJ, Chandler JR, Blackwell HE.	Sci Rep	10.1038/s41598-019-49693-x	2019
Genetics	Complete genome sequence and analysis of Alcaligenes faecalis strain Mc250, a new potential plant bioinoculant.	Felestrino EB, Sanchez AB, Caneschi WL, Lemes CGC, Assis RAB, Cordeiro IF, Fonseca NP, Villa MM, Vieira IT, Kamino LHY, do Carmo FF, da Silva AM, Thomas AM, Patane JSL, Ferreira FC, de Freitas LG, Varani AM, Ferro JA, Silva RS, Almeida NF, Garcia CCM, Setubal JC, Moreira LM.	PLoS One	10.1371/journal.pone.0241546	2020
Metabolism	Characterization of para-Nitrophenol-Degrading Bacterial Communities in River Water by Using Functional Markers and Stable Isotope Probing.	Kowalczyk A, Eyice O, Schafer H, Price OR, Finnegan CJ, van Egmond RA, Shaw LJ, Barrett G, Bending GD.	Appl Environ Microbiol	10.1128/aem.01794-15	2015
Metabolism	Ferric Uptake Regulator Fur Coordinates Siderophore Production and Defense against Iron Toxicity and Oxidative Stress and Contributes to Virulence in Chromobacterium violaceum.	Santos RERS, Batista BB, da Silva Neto JF.	Appl Environ Microbiol	10.1128/aem.01620-20	2020
	The art of persistence-the secrets to Burkholderia chronic infections.	Lewis ER, Torres AG.	Pathog Dis	10.1093/femspd/ftw070	2016
	A novel family of toxin/antitoxin proteins in Bacillus species.	Holberger LE, Garza-Sanchez F, Lamoureux J, Low DA, Hayes CS.	FEBS Lett	10.1016/j.febslet.2011.12.020	2012
Enzymology	Molecular comparison of isolates of Burkholderia multivorans from patients with cystic fibrosis in the United Kingdom.	Turton JF, Kaufmann ME, Mustafa N, Kawa S, Clode FE, Pitt TL.	J Clin Microbiol	10.1128/jcm.41.12.5750-5754.2003	2003
Genetics	Genome Analysis of a Novel Broad Host Range Proteobacteria Phage Isolated from a Bioreactor Treating Industrial Wastewater.	de Leeuw M, Baron M, Brenner A, Kushmaro A.	Genes (Basel)	10.3390/genes8010040	2017
Metabolism	Three feruloyl esterases in Cellulosilyticum ruminicola H1 act synergistically to hydrolyze esterified polysaccharides.	Li J, Cai S, Luo Y, Dong X.	Appl Environ Microbiol	10.1128/aem.00657-11	2011
Phylogeny	The Variability of the Order Burkholderiales Representatives in the Healthcare Units.	Voronina OL, Kunda MS, Ryzhova NN, Aksenova EI, Semenov AN, Lasareva AV, Amelina EL, Chuchalin AG, Lunin VG, Gintsburg AL.	Biomed Res Int	10.1155/2015/680210	2015
	Single particle tracking reveals spatial and dynamic organization of the E. coli biofilm matrix.	Birjiniuk A, Billings N, Nance E, Hanes J, Ribbeck K, Doyle PS.	New J Phys	10.1088/1367-2630/16/8/085014	2014
Genetics	Genomic analyses of Burkholderia cenocepacia reveal multiple species with differential host-adaptation to plants and humans.	Wallner A, King E, Ngonkeu ELM, Moulin L, Bena G.	BMC Genomics	10.1186/s12864-019-6186-z	2019
	Ecological Succession of Polymicrobial Communities in the Cystic Fibrosis Airways.	Khanolkar RA, Clark ST, Wang PW, Hwang DM, Yau YCW, Waters VJ, Guttman DS.	mSystems	10.1128/msystems.00809-20	2020
Enzymology	Comparison of DNA extraction methods for microbial community profiling with an application to pediatric bronchoalveolar lavage samples.	Willner D, Daly J, Whiley D, Grimwood K, Wainwright CE, Hugenholtz P.	PLoS One	10.1371/journal.pone.0034605	2012
Metabolism	The Pseudomonas aeruginosa Complement of Lactate Dehydrogenases Enables Use of d- and l-Lactate and Metabolic Cross-Feeding.	Lin YC, Cornell WC, Jo J, Price-Whelan A, Dietrich LEP.	mBio	10.1128/mbio.00961-18	2018
Metabolism	Arsenite oxidase from Ralstonia sp. 22: characterization of the enzyme and its interaction with soluble cytochromes.	Lieutaud A, van Lis R, Duval S, Capowiez L, Muller D, Lebrun R, Lignon S, Fardeau ML, Lett MC, Nitschke W, Schoepp-Cothenet B.	J Biol Chem	10.1074/jbc.m110.113761	2010
	Comparative Genomics of Environmental and Clinical Burkholderia cenocepacia Strains Closely Related to the Highly Transmissible Epidemic ET12 Lineage.	Bodilis J, Denet E, Brothier E, Graindorge A, Favre-Bonte S, Nazaret S.	Front Microbiol	10.3389/fmicb.2018.00383	2018
	Can early Burkholderia cepacia complex infection in cystic fibrosis be eradicated with antibiotic therapy?	Horsley A, Webb K, Bright-Thomas R, Govan J, Jones A.	Front Cell Infect Microbiol	10.3389/fcimb.2011.00018	2011
Pathogenicity	Evaluation of liquid and solid culture media for the recovery and enrichment of Burkholderia cenocepacia from distilled water.	Ahn Y, Kim JM, Ahn H, Lee YJ, LiPuma JJ, Hussong D, Cerniglia CE.	J Ind Microbiol Biotechnol	10.1007/s10295-014-1442-3	2014
Metabolism	Light-inducible carotenoid production controlled by a MarR-type regulator in Corynebacterium glutamicum.	Sumi S, Suzuki Y, Matsuki T, Yamamoto T, Tsuruta Y, Mise K, Kawamura T, Ito Y, Shimada Y, Watanabe E, Watanabe S, Toriyabe M, Takano Shiratori H, Ueda K, Takano H.	Sci Rep	10.1038/s41598-019-49384-7	2019
	Gene expression profiling of Burkholderia cenocepacia at the time of cepacia syndrome: loss of motility as a marker of poor prognosis?	Kalferstova L, Kolar M, Fila L, Vavrova J, Drevinek P.	J Clin Microbiol	10.1128/jcm.03605-14	2015
Metabolism	Light Response of Pseudomonas putida KT2440 Mediated by Class II LitR, a Photosensor Homolog.	Sumi S, Mutaguchi N, Ebuchi T, Tsuchida H, Yamamoto T, Suzuki M, Natsuka C, Shiratori-Takano H, Shintani M, Nojiri H, Ueda K, Takano H.	J Bacteriol	10.1128/jb.00146-20	2020
	Utility of platforms Viteks MS and Microflex LT for the identification of complex clinical isolates that require molecular methods for their taxonomic classification.	Rocca MF, Barrios R, Zintgraff J, Martinez C, Irazu L, Vay C, Prieto M.	PLoS One	10.1371/journal.pone.0218077	2019
Pathogenicity	Structural Variabilities in beta-Lactamase (blaA) of Different Biovars of Yersinia enterocolitica: Implications for beta-Lactam Antibiotic and beta-Lactamase Inhibitor Susceptibilities.	Singhal N, Srivastava A, Kumar M, Virdi JS.	PLoS One	10.1371/journal.pone.0123564	2014
Metabolism	Abundant and diverse arsenic-metabolizing microorganisms in peatlands treating arsenic-contaminated mining wastewaters.	Kujala K, Besold J, Mikkonen A, Tiirola M, Planer-Friedrich B.	Environ Microbiol	10.1111/1462-2920.14922	2020
Enzymology	Determinants of Cofactor Specificity for the Glucose-6-Phosphate Dehydrogenase from Escherichia coli: Simulation, Kinetics and Evolutionary Studies.	Fuentealba M, Munoz R, Maturana P, Krapp A, Cabrera R.	PLoS One	10.1371/journal.pone.0152403	2016
Pathogenicity	Synthesis, characterization, and antimicrobial activity of silver carbene complexes derived from 4,5,6,7-tetrachlorobenzimidazole against antibiotic resistant bacteria.	Wright BD, Shah PN, McDonald LJ, Shaeffer ML, Wagers PO, Panzner MJ, Smolen J, Tagaev J, Tessier CA, Cannon CL, Youngs WJ.	Dalton Trans	10.1039/c2dt00055e	2012
Pathogenicity	Direct comparison of the BD phoenix system with the MicroScan WalkAway system for identification and antimicrobial susceptibility testing of Enterobacteriaceae and nonfermentative gram-negative organisms.	Snyder JW, Munier GK, Johnson CL.	J Clin Microbiol	10.1128/jcm.00075-08	2008
	Inorganic Phosphate Solubilization by Rhizosphere Bacterium Paenibacillus sonchi: Gene Expression and Physiological Functions.	Brito LF, Lopez MG, Straube L, Passaglia LMP, Wendisch VF.	Front Microbiol	10.3389/fmicb.2020.588605	2020
	Misidentification of Pandoraea sputorum isolated from sputum of a patient with cystic fibrosis and review of Pandoraea species infections in transplant patients.	Pimentel JD, MacLeod C.	J Clin Microbiol	10.1128/jcm.00855-08	2008
	Mycobacterium abscessus subsp. abscessus Is Capable of Degrading Pseudomonas aeruginosa Quinolone Signals.	Birmes FS, Wolf T, Kohl TA, Ruger K, Bange F, Kalinowski J, Fetzner S.	Front Microbiol	10.3389/fmicb.2017.00339	2017
Metabolism	The Burkholderia cenocepacia Type VI Secretion System Effector TecA Is a Virulence Factor in Mouse Models of Lung Infection.	Loeven NA, Perault AI, Cotter PA, Hodges CA, Schwartzman JD, Hampton TH, Bliska JB.	mBio	10.1128/mbio.02098-21	2021
Metabolism	Genome mining identifies cepacin as a plant-protective metabolite of the biopesticidal bacterium Burkholderia ambifaria.	Mullins AJ, Murray JAH, Bull MJ, Jenner M, Jones C, Webster G, Green AE, Neill DR, Connor TR, Parkhill J, Challis GL, Mahenthiralingam E.	Nat Microbiol	10.1038/s41564-019-0383-z	2019
	2-Aminoacetophenone as a potential breath biomarker for Pseudomonas aeruginosa in the cystic fibrosis lung.	Scott-Thomas AJ, Syhre M, Pattemore PK, Epton M, Laing R, Pearson J, Chambers ST.	BMC Pulm Med	10.1186/1471-2466-10-56	2010
Metabolism	Functional Characterization of a Novel Member of the Amidohydrolase 2 Protein Family, 2-Hydroxy-1-Naphthoic Acid Nonoxidative Decarboxylase from Burkholderia sp. Strain BC1.	Pal Chowdhury P, Basu S, Dutta A, Dutta TK.	J Bacteriol	10.1128/jb.00250-16	2016
	Common severe infections in chronic granulomatous disease.	Marciano BE, Spalding C, Fitzgerald A, Mann D, Brown T, Osgood S, Yockey L, Darnell DN, Barnhart L, Daub J, Boris L, Rump AP, Anderson VL, Haney C, Kuhns DB, Rosenzweig SD, Kelly C, Zelazny A, Mason T, DeRavin SS, Kang E, Gallin JI, Malech HL, Olivier KN, Uzel G, Freeman AF, Heller T, Zerbe CS, Holland SM.	Clin Infect Dis	10.1093/cid/ciu1154	2015
Proteome	Relationships Between Copper-Related Proteomes and Lifestyles in beta Proteobacteria.	Antoine R, Rivera-Millot A, Roy G, Jacob-Dubuisson F.	Front Microbiol	10.3389/fmicb.2019.02217	2019
Enzymology	Identification of a five-oxidoreductase-gene cluster from Acetobacter pasteurianus conferring ethanol-dependent acidification in Escherichia coli.	Garcia-Armisen T, Vercammen K, Rimaux T, Vrancken G, Vuyst LD, Cornelis P.	Microbiologyopen	10.1002/mbo3.4	2012
Enzymology	Burkholderia pseudomallei: Challenges for the Clinical Microbiology Laboratory.	Hemarajata P, Baghdadi JD, Hoffman R, Humphries RM.	J Clin Microbiol	10.1128/jcm.01636-16	2016
Genetics	Genomic and Phenotypic Evolution of Achromobacter xylosoxidans during Chronic Airway Infections of Patients with Cystic Fibrosis.	Khademi SMH, Gabrielaite M, Paulsson M, Knulst M, Touriki E, Marvig RL, Pahlman LI.	mSystems	10.1128/msystems.00523-21	2021
Metabolism	Control of hmu Heme Uptake Genes in Yersinia pseudotuberculosis in Response to Iron Sources.	Schwiesow L, Mettert E, Wei Y, Miller HK, Herrera NG, Balderas D, Kiley PJ, Auerbuch V.	Front Cell Infect Microbiol	10.3389/fcimb.2018.00047	2018
	Hopanoid-free Methylobacterium extorquens DM4 overproduces carotenoids and has widespread growth impairment.	Bradley AS, Swanson PK, Muller EE, Bringel F, Caroll SM, Pearson A, Vuilleumier S, Marx CJ.	PLoS One	10.1371/journal.pone.0173323	2017
	Structural and functional characterization of an intradiol ring-cleavage dioxygenase from the polyphagous spider mite herbivore Tetranychus urticae Koch.	Schlachter CR, Daneshian L, Amaya J, Klapper V, Wybouw N, Borowski T, Van Leeuwen T, Grbic V, Grbic M, Makris TM, Chruszcz M.	Insect Biochem Mol Biol	10.1016/j.ibmb.2018.12.001	2019
Metabolism	Novel Feruloyl Esterase from Lactobacillus fermentum NRRL B-1932 and Analysis of the Recombinant Enzyme Produced in Escherichia coli.	Liu S, Bischoff KM, Anderson AM, Rich JO.	Appl Environ Microbiol	10.1128/aem.01029-16	2016
	The Response of Cupriavidus metallidurans CH34 to Cadmium Involves Inhibition of the Initiation of Biofilm Formation, Decrease in Intracellular c-di-GMP Levels, and a Novel Metal Regulated Phosphodiesterase.	Alviz-Gazitua P, Fuentes-Alburquenque S, Rojas LA, Turner RJ, Guiliani N, Seeger M.	Front Microbiol	10.3389/fmicb.2019.01499	2019
Proteome	Impact of chlorhexidine digluconate and temperature on curli production in Escherichia coli-consequence on its adhesion ability.	Coquet L, Obry A, Borghol N, Hardouin J, Mora L, Othmane A, Jouenne T.	AIMS Microbiol	10.3934/microbiol.2017.4.915	2017
Pathogenicity	Peptide conjugated phosphorodiamidate morpholino oligomers increase survival of mice challenged with Ames Bacillus anthracis.	Panchal RG, Geller BL, Mellbye B, Lane D, Iversen PL, Bavari S.	Nucleic Acid Ther	10.1089/nat.2012.0362	2012
Genetics	The Essential Genome of Burkholderia cenocepacia H111.	Higgins S, Sanchez-Contreras M, Gualdi S, Pinto-Carbo M, Carlier A, Eberl L.	J Bacteriol	10.1128/jb.00260-17	2017
Enzymology	Development of rRNA-based PCR assays for identification of Burkholderia cepacia complex isolates recovered from cystic fibrosis patients.	LiPuma JJ, Dulaney BJ, McMenamin JD, Whitby PW, Stull TL, Coenye T, Vandamme P.	J Clin Microbiol	10.1128/jcm.37.10.3167-3170.1999	1999
Pathogenicity	Genomic evidence reveals the extreme diversity and wide distribution of the arsenic-related genes in Burkholderiales.	Li X, Zhang L, Wang G.	PLoS One	10.1371/journal.pone.0092236	2014
	Nanoparticle-mediated pulmonary drug delivery: state of the art towards efficient treatment of recalcitrant respiratory tract bacterial infections.	Huang Z, Klodzinska SN, Wan F, Nielsen HM.	Drug Deliv Transl Res	10.1007/s13346-021-00954-1	2021
	Distribution and Inhibition of Liposomes on Staphylococcus aureus and Pseudomonas aeruginosa Biofilm.	Dong D, Thomas N, Thierry B, Vreugde S, Prestidge CA, Wormald PJ.	PLoS One	10.1371/journal.pone.0131806	2015
	Assortment of carbon sources in medium for Yarrowia lipolytica lipase production: A statistical approach.	Fabiszewska AU, Kotyrba D, Nowak D.	Ann Microbiol	10.1007/s13213-014-0988-7	2015
	Understanding the Pathogenicity of Burkholderia contaminans, an Emerging Pathogen in Cystic Fibrosis.	Nunvar J, Kalferstova L, Bloodworth RA, Kolar M, Degrossi J, Lubovich S, Cardona ST, Drevinek P.	PLoS One	10.1371/journal.pone.0160975	2016
	Soil biochar amendment affects the diversity of nosZ transcripts: Implications for N₂O formation.	Harter J, El-Hadidi M, El-Hadidi M, Huson DH, Kappler A, Behrens S.	Sci Rep	10.1038/s41598-017-03282-y	2017
Phylogeny	Discrimination of Burkholderia multivorans and Burkholderia vietnamiensis from Burkholderia cepacia genomovars I, III, and IV by PCR.	Bauernfeind A, Schneider I, Jungwirth R, Roller C.	J Clin Microbiol	10.1128/jcm.37.5.1335-1339.1999	1999
Enzymology	Factors influencing acquisition of Burkholderia cepacia complex organisms in patients with cystic fibrosis.	Ramsay KA, Butler CA, Paynter S, Ware RS, Kidd TJ, Wainwright CE, Bell SC.	J Clin Microbiol	10.1128/jcm.01360-13	2013
Metabolism	A tale of two oxidation states: bacterial colonization of arsenic-rich environments.	Muller D, Medigue C, Koechler S, Barbe V, Barakat M, Talla E, Bonnefoy V, Krin E, Arsene-Ploetze F, Carapito C, Chandler M, Cournoyer B, Cruveiller S, Dossat C, Duval S, Heymann M, Leize E, Lieutaud A, Lievremont D, Makita Y, Mangenot S, Nitschke W, Ortet P, Perdrial N, Schoepp B, Siguier P, Simeonova DD, Rouy Z, Segurens B, Turlin E, Vallenet D, Van Dorsselaer A, Weiss S, Weissenbach J, Lett MC, Danchin A, Bertin PN.	PLoS Genet	10.1371/journal.pgen.0030053	2007
	Revelation of the ability of Burkholderia sp. USM (JCM 15050) PHA synthase to polymerize 4-hydroxybutyrate monomer.	Lau NS, Sudesh K.	AMB Express	10.1186/2191-0855-2-41	2012
	Colonization strategies of Pseudomonas fluorescens Pf0-1: activation of soil-specific genes important for diverse and specific environments.	Varivarn K, Champa LA, Silby MW, Robleto EA.	BMC Microbiol	10.1186/1471-2180-13-92	2013
	Surveillance bronchoscopy in children during the first year after lung transplantation: Is it worth it?	Benden C, Harpur-Sinclair O, Ranasinghe AS, Hartley JC, Elliott MJ, Aurora P.	Thorax	10.1136/thx.2006.063404	2007
Genetics	Comparative analysis of two phenotypically-similar but genomically-distinct Burkholderia cenocepacia-specific bacteriophages.	Lynch KH, Stothard P, Dennis JJ, Dennis JJ.	BMC Genomics	10.1186/1471-2164-13-223	2012
Metabolism	Structural and functional characterization of diffusible signal factor family quorum-sensing signals produced by members of the Burkholderia cepacia complex.	Deng Y, Wu J, Eberl L, Zhang LH.	Appl Environ Microbiol	10.1128/aem.00480-10	2010
Metabolism	Global Analysis of the Fungal Microbiome in Cystic Fibrosis Patients Reveals Loss of Function of the Transcriptional Repressor Nrg1 as a Mechanism of Pathogen Adaptation.	Kim SH, Clark ST, Surendra A, Copeland JK, Wang PW, Ammar R, Collins C, Tullis DE, Nislow C, Hwang DM, Guttman DS, Cowen LE.	PLoS Pathog	10.1371/journal.ppat.1005308	2015
	Mosaic structure of intragenic repetitive elements in histone H1-like protein Hc2 varies within serovars of Chlamydia trachomatis.	Klint M, Thollesson M, Bongcam-Rudloff E, Birkelund S, Nilsson A, Herrmann B.	BMC Microbiol	10.1186/1471-2180-10-81	2010
	Burkholderia cepacia Complex Regulation of Virulence Gene Expression: A Review.	Sousa SA, Feliciano JR, Pita T, Guerreiro SI, Leitao JH.	Genes (Basel)	10.3390/genes8010043	2017
Phylogeny	Increasing genomic diversity and evidence of constrained lifestyle evolution due to insertion sequences in Aeromonas salmonicida.	Vincent AT, Trudel MV, Freschi L, Nagar V, Gagne-Thivierge C, Levesque RC, Charette SJ.	BMC Genomics	10.1186/s12864-016-2381-3	2016
Metabolism	Comparative metabolic systems analysis of pathogenic Burkholderia.	Bartell JA, Yen P, Varga JJ, Goldberg JB, Papin JA.	J Bacteriol	10.1128/jb.00997-13	2014
Genetics	Distribution and Classification of Serine beta-Lactamases in Brazilian Hospital Sewage and Other Environmental Metagenomes Deposited in Public Databases.	Froes AM, da Mota FF, Cuadrat RR, Davila AM.	Front Microbiol	10.3389/fmicb.2016.01790	2016
	Organisms isolated from adults with cystic fibrosis.	McManus TE, McDowell A, Moore JE, Elborn SJ.	Ann Clin Microbiol Antimicrob	10.1186/1476-0711-3-26	2004
Enzymology	The temperate Burkholderia phage AP3 of the Peduovirinae shows efficient antimicrobial activity against B. cenocepacia of the IIIA lineage.	Roszniowski B, Latka A, Maciejewska B, Vandenheuvel D, Olszak T, Briers Y, Holt GS, Valvano MA, Lavigne R, Smith DL, Drulis-Kawa Z.	Appl Microbiol Biotechnol	10.1007/s00253-016-7924-7	2017
	A decade of Burkholderia cenocepacia virulence determinant research.	Loutet SA, Valvano MA.	Infect Immun	10.1128/iai.00212-10	2010
Pathogenicity	Deep Sequencing of RNA from Blood and Oral Swab Samples Reveals the Presence of Nucleic Acid from a Number of Pathogens in Patients with Acute Ebola Virus Disease and Is Consistent with Bacterial Translocation across the Gut.	Carroll MW, Haldenby S, Rickett NY, Palyi B, Garcia-Dorival I, Liu X, Barker G, Bore JA, Koundouno FR, Williamson ED, Laws TR, Kerber R, Sissoko D, Magyar N, Di Caro A, Biava M, Fletcher TE, Sprecher A, Ng LFP, Renia L, Magassouba N, Gunther S, Wolfel R, Stoecker K, Matthews DA, Hiscox JA.	mSphere	10.1128/mspheredirect.00325-17	2017
	Kinetic modeling, production and characterization of an acidic lipase produced by Enterococcus durans NCIM5427 from fish waste.	Ramakrishnan V, Goveas LC, Halami PM, Narayan B.	J Food Sci Technol	10.1007/s13197-013-1141-5	2015
Transcriptome	The PathoChip, a functional gene array for assessing pathogenic properties of diverse microbial communities.	Lee YJ, van Nostrand JD, Tu Q, Lu Z, Cheng L, Yuan T, Deng Y, Carter MQ, He Z, Wu L, Yang F, Xu J, Zhou J.	ISME J	10.1038/ismej.2013.88	2013
	The role of the bacterial protease Prc in the uropathogenesis of extraintestinal pathogenic Escherichia coli.	Huang WC, Lin CY, Hashimoto M, Wu JJ, Wang MC, Lin WH, Chen CS, Teng CH.	J Biomed Sci	10.1186/s12929-019-0605-y	2020
Enzymology	Suppurative mediastinitis secondary to Burkholderia cepacia in a patient with cystic fibrosis.	George RB, Cartier Y, Casson AG, Hernandez P.	Can Respir J	10.1155/2006/495720	2006
Enzymology	Microbial oxidation of arsenite in a subarctic environment: diversity of arsenite oxidase genes and identification of a psychrotolerant arsenite oxidiser.	Osborne TH, Jamieson HE, Hudson-Edwards KA, Nordstrom DK, Walker SR, Ward SA, Santini JM.	BMC Microbiol	10.1186/1471-2180-10-205	2010
Pathogenicity	Synthesis, characterization, and antibacterial activity of cross-linked chitosan-glutaraldehyde.	Li B, Shan CL, Zhou Q, Fang Y, Wang YL, Xu F, Han LR, Ibrahim M, Guo LB, Xie GL, Sun GC.	Mar Drugs	10.3390/md11051534	2013
Genetics	Combining structure and genomics to understand antimicrobial resistance.	Tunstall T, Portelli S, Phelan J, Clark TG, Ascher DB, Furnham N.	Comput Struct Biotechnol J	10.1016/j.csbj.2020.10.017	2020
	Physiological levels of nitrate support anoxic growth by denitrification of Pseudomonas aeruginosa at growth rates reported in cystic fibrosis lungs and sputum.	Line L, Alhede M, Kolpen M, Kuhl M, Ciofu O, Bjarnsholt T, Moser C, Toyofuku M, Nomura N, Hoiby N, Jensen PO.	Front Microbiol	10.3389/fmicb.2014.00554	2014
Metabolism	Identification of the flagellin glycosylation system in Burkholderia cenocepacia and the contribution of glycosylated flagellin to evasion of human innate immune responses.	Hanuszkiewicz A, Pittock P, Humphries F, Moll H, Rosales AR, Molinaro A, Moynagh PN, Lajoie GA, Valvano MA.	J Biol Chem	10.1074/jbc.m114.562603	2014
Phylogeny	Novel pan-genomic analysis approach in target selection for multiplex PCR identification and detection of Burkholderia pseudomallei, Burkholderia thailandensis, and Burkholderia cepacia complex species: a proof-of-concept study.	Ho CC, Lau CC, Martelli P, Chan SY, Tse CW, Wu AK, Yuen KY, Lau SK, Woo PC.	J Clin Microbiol	10.1128/jcm.01702-10	2011
Phylogeny	DNA-Based diagnostic approaches for identification of Burkholderia cepacia complex, Burkholderia vietnamiensis, Burkholderia multivorans, Burkholderia stabilis, and Burkholderia cepacia genomovars I and III.	Mahenthiralingam E, Bischof J, Byrne SK, Radomski C, Davies JE, Av-Gay Y, Vandamme P.	J Clin Microbiol	10.1128/jcm.38.9.3165-3173.2000	2000
	Immune Recognition of the Epidemic Cystic Fibrosis Pathogen Burkholderia dolosa.	Roux D, Weatherholt M, Clark B, Gadjeva M, Renaud D, Scott D, Skurnik D, Priebe GP, Pier G, Gerard C, Yoder-Himes DR.	Infect Immun	10.1128/iai.00765-16	2017
	Synthetic Phosphodiester-Linked 4-Amino-4-deoxy-l-arabinose Derivatives Demonstrate that ArnT is an Inverting Aminoarabinosyl Transferase.	Olagnon C, Monjaras Feria J, Grunwald-Gruber C, Blaukopf M, Valvano MA, Kosma P.	Chembiochem	10.1002/cbic.201900349	2019
Phylogeny	Optimization of routine identification of clinically relevant Gram-negative bacteria by use of matrix-assisted laser desorption ionization-time of flight mass spectrometry and the Bruker Biotyper.	Ford BA, Burnham CA.	J Clin Microbiol	10.1128/jcm.01803-12	2013
	Molecular analysis of beta-lactamase genes to understand their differential expression in strains of Yersinia enterocolitica biotype 1A.	Singhal N, Kumar M, Virdi JS.	Sci Rep	10.1038/srep05270	2014
	Aerosol phage therapy efficacy in Burkholderia cepacia complex respiratory infections.	Semler DD, Goudie AD, Finlay WH, Dennis JJ, Dennis JJ.	Antimicrob Agents Chemother	10.1128/aac.02388-13	2014
Metabolism	Low iron-induced small RNA BrrF regulates central metabolism and oxidative stress responses in Burkholderia cenocepacia.	Sass AM, Coenye T.	PLoS One	10.1371/journal.pone.0236405	2020
	Nasal immunization with Burkholderia multivorans outer membrane proteins and the mucosal adjuvant adamantylamide dipeptide confers efficient protection against experimental lung infections with B. multivorans and B. cenocepacia.	Bertot GM, Restelli MA, Galanternik L, Aranibar Urey RC, Valvano MA, Grinstein S.	Infect Immun	10.1128/iai.01668-06	2007
Phylogeny	One case each of recurrent meningitis and hemoperitoneum infection with Ralstonia mannitolilytica.	Vaneechoutte M, De Baere T, Wauters G, Steyaert S, Claeys G, Vogelaers D, Verschraegen G.	J Clin Microbiol	10.1128/jcm.39.12.4588-4590.2001	2001
	Genomic Stability of Aggregatibacter actinomycetemcomitans during Persistent Oral Infection in Human.	Sun R, Kittichotirat W, Wang J, Jan M, Chen W, Asikainen S, Bumgarner R, Chen C.	PLoS One	10.1371/journal.pone.0066472	2013
Genetics	Prediction and characterization of enzymatic activities guided by sequence similarity and genome neighborhood networks.	Zhao S, Sakai A, Zhang X, Vetting MW, Kumar R, Hillerich B, San Francisco B, Solbiati J, Steves A, Brown S, Akiva E, Barber A, Seidel RD, Babbitt PC, Almo SC, Gerlt JA, Jacobson MP.	Elife	10.7554/elife.03275	2014
Metabolism	l-Galactose metabolism in Bacteroides vulgatus from the human gut microbiota.	Hobbs ME, Williams HJ, Hillerich B, Almo SC, Raushel FM.	Biochemistry	10.1021/bi500656m	2014
	Infections in patients with cystic fibrosis: diagnostic microbiology update.	Gilligan PH.	Clin Lab Med	10.1016/j.cll.2014.02.001	2014
Metabolism	Biochemical characterization of a first fungal esterase from Rhizomucor miehei showing high efficiency of ester synthesis.	Liu Y, Xu H, Yan Q, Yang S, Duan X, Jiang Z.	PLoS One	10.1371/journal.pone.0077856	2013
	Structure of O-Antigen and Hybrid Biosynthetic Locus in Burkholderia cenocepacia Clonal Variants Recovered from a Cystic Fibrosis Patient.	Hassan AA, Maldonado RF, Dos Santos SC, Di Lorenzo F, Silipo A, Coutinho CP, Cooper VS, Molinaro A, Valvano MA, Sa-Correia I.	Front Microbiol	10.3389/fmicb.2017.01027	2017
Metabolism	Distribution and organization of auxotrophic genes on the multichromosomal genome of Burkholderia multivorans ATCC 17616.	Komatsu H, Imura Y, Ohori A, Nagata Y, Tsuda M.	J Bacteriol	10.1128/jb.185.11.3333-3343.2003	2003
Pathogenicity	A small molecule that mitigates bacterial infection disrupts Gram-negative cell membranes and is inhibited by cholesterol and neutral lipids.	Dombach JL, Quintana JLJ, Nagy TA, Wan C, Crooks AL, Yu H, Su CC, Yu EW, Shen J, Detweiler CS.	PLoS Pathog	10.1371/journal.ppat.1009119	2020
Enzymology	Naturally occurring Class A ss-lactamases from the Burkholderia cepacia complex.	Poirel L, Rodriguez-Martinez JM, Plesiat P, Nordmann P.	Antimicrob Agents Chemother	10.1128/aac.00946-08	2009
Metabolism	Surface changes and polymyxin interactions with a resistant strain of Klebsiella pneumoniae.	Velkov T, Deris ZZ, Huang JX, Azad MA, Butler M, Sivanesan S, Kaminskas LM, Dong YD, Boyd B, Baker MA, Cooper MA, Nation RL, Li J.	Innate Immun	10.1177/1753425913493337	2014
	Innate immunity against Granulibacter bethesdensis, an emerging gram-negative bacterial pathogen.	Zarember KA, Marshall-Batty KR, Cruz AR, Chu J, Fenster ME, Shoffner AR, Rogge LS, Whitney AR, Czapiga M, Song HH, Shaw PA, Nagashima K, Malech HL, DeLeo FR, Holland SM, Gallin JI, Greenberg DE.	Infect Immun	10.1128/iai.05557-11	2012
Phylogeny	Phenotypic methods for determining genomovar status of the Burkholderia cepacia complex.	Henry DA, Mahenthiralingam E, Vandamme P, Coenye T, Speert DP.	J Clin Microbiol	10.1128/jcm.39.3.1073-1078.2001	2001
	Cyanide Toxicity to Burkholderia cenocepacia Is Modulated by Polymicrobial Communities and Environmental Factors.	Bernier SP, Workentine ML, Li X, Magarvey NA, O'Toole GA, Surette MG.	Front Microbiol	10.3389/fmicb.2016.00725	2016
Metabolism	Burkholderia cenocepacia O polysaccharide chain contributes to caspase-1-dependent IL-1beta production in macrophages.	Kotrange S, Kopp B, Akhter A, Abdelaziz D, Abu Khweek A, Caution K, Abdulrahman B, Wewers MD, McCoy K, Marsh C, Loutet SA, Ortega X, Valvano MA, Amer AO.	J Leukoc Biol	10.1189/jlb.0910513	2011
Enzymology	Rod-shape theranostic nanoparticles facilitate antiretroviral drug biodistribution and activity in human immunodeficiency virus susceptible cells and tissues.	Kevadiya BD, Ottemann B, Mukadam IZ, Castellanos L, Sikora K, Hilaire JR, Machhi J, Herskovitz J, Soni D, Hasan M, Zhang W, Anandakumar S, Garrison J, McMillan J, Edagwa B, Mosley RL, Vachet RW, Gendelman HE.	Theranostics	10.7150/thno.39847	2020
Phylogeny	Bacterial leaf symbiosis in angiosperms: host specificity without co-speciation.	Lemaire B, Vandamme P, Merckx V, Smets E, Dessein S.	PLoS One	10.1371/journal.pone.0024430	2011
	The tyrosine kinase BceF and the phosphotyrosine phosphatase BceD of Burkholderia contaminans are required for efficient invasion and epithelial disruption of a cystic fibrosis lung epithelial cell line.	Ferreira AS, Silva IN, Fernandes F, Pilkington R, Callaghan M, McClean S, Moreira LM.	Infect Immun	10.1128/iai.02713-14	2015
	Immunogenic Consensus Sequence T helper Epitopes for a Pan-Burkholderia Biodefense Vaccine.	De Groot AS, Ardito M, Moise L, Gustafson EA, Spero D, Tejada G, Martin W.	Immunome Res	10.4172/1745-7580.1000043	2011
Metabolism	Tyrosine Phosphorylation and Dephosphorylation in Burkholderia cenocepacia Affect Biofilm Formation, Growth under Nutritional Deprivation, and Pathogenicity.	Andrade A, Tavares-Carreon F, Khodai-Kalaki M, Valvano MA.	Appl Environ Microbiol	10.1128/aem.03513-15	2016
Metabolism	Burkholderia BcpA mediates biofilm formation independently of interbacterial contact-dependent growth inhibition.	Garcia EC, Anderson MS, Hagar JA, Cotter PA.	Mol Microbiol	10.1111/mmi.12339	2013
	The YhhN protein of Legionella pneumophila is a Lysoplasmalogenase.	Jurkowitz MS, Patel A, Wu LC, Krautwater A, Pfeiffer DR, Bell CE.	Biochim Biophys Acta	10.1016/j.bbamem.2014.11.011	2015
Phylogeny	Evaluation of matrix-assisted laser desorption ionization-time-of-flight mass spectrometry in comparison to 16S rRNA gene sequencing for species identification of nonfermenting bacteria.	Mellmann A, Cloud J, Maier T, Keckevoet U, Ramminger I, Iwen P, Dunn J, Hall G, Wilson D, Lasala P, Kostrzewa M, Harmsen D.	J Clin Microbiol	10.1128/jcm.00157-08	2008
Metabolism	Promiscuous Diffusible Signal Factor Production and Responsiveness of the Xylella fastidiosa Rpf System.	Ionescu M, Yokota K, Antonova E, Garcia A, Beaulieu E, Hayes T, Iavarone AT, Lindow SE.	mBio	10.1128/mbio.01054-16	2016
Pathogenicity	Key role for efflux in the preservative susceptibility and adaptive resistance of Burkholderia cepacia complex bacteria.	Rushton L, Sass A, Baldwin A, Dowson CG, Donoghue D, Mahenthiralingam E.	Antimicrob Agents Chemother	10.1128/aac.00140-13	2013
Phylogeny	Oxidative stress of Burkholderia cenocepacia induces insertion sequence-mediated genomic rearrangements that interfere with macrorestriction-based genotyping.	Drevinek P, Baldwin A, Lindenburg L, Joshi LT, Marchbank A, Vosahlikova S, Dowson CG, Mahenthiralingam E.	J Clin Microbiol	10.1128/jcm.01433-09	2010
	Localization of Burkholderia cepacia complex bacteria in cystic fibrosis lungs and interactions with Pseudomonas aeruginosa in hypoxic mucus.	Schwab U, Abdullah LH, Perlmutt OS, Albert D, Davis CW, Arnold RR, Yankaskas JR, Gilligan P, Neubauer H, Randell SH, Boucher RC.	Infect Immun	10.1128/iai.01876-14	2014
Metabolism	Biofilm-grown Burkholderia cepacia complex cells survive antibiotic treatment by avoiding production of reactive oxygen species.	Van Acker H, Sass A, Bazzini S, De Roy K, Udine C, Messiaen T, Riccardi G, Boon N, Nelis HJ, Mahenthiralingam E, Coenye T.	PLoS One	10.1371/journal.pone.0058943	2013
Metabolism	Linocin and OmpW Are Involved in Attachment of the Cystic Fibrosis-Associated Pathogen Burkholderia cepacia Complex to Lung Epithelial Cells and Protect Mice against Infection.	McClean S, Healy ME, Collins C, Carberry S, O'Shaughnessy L, Dennehy R, Adams A, Kennelly H, Corbett JM, Carty F, Cahill LA, Callaghan M, English K, Mahon BP, Doyle S, Shinoy M.	Infect Immun	10.1128/iai.01248-15	2016
Phylogeny	Comparative genomic and phylogenetic approaches to characterize the role of genetic recombination in mycobacterial evolution.	Smith SE, Showers-Corneli P, Dardenne CN, Harpending HH, Martin DP, Beiko RG.	PLoS One	10.1371/journal.pone.0050070	2012
Metabolism	Identification of Burkholderia cenocepacia strain H111 virulence factors using nonmammalian infection hosts.	Schwager S, Agnoli K, Kothe M, Feldmann F, Givskov M, Carlier A, Eberl L.	Infect Immun	10.1128/iai.00768-12	2013
Metabolism	Host Range of the Conjugative Transfer System of IncP-9 Naphthalene-Catabolic Plasmid NAH7 and Characterization of Its oriT Region and Relaxase.	Kishida K, Inoue K, Ohtsubo Y, Nagata Y, Tsuda M.	Appl Environ Microbiol	10.1128/aem.02359-16	2017
Metabolism	Role of bacteriocins in mediating interactions of bacterial isolates taken from cystic fibrosis patients.	Bakkal S, Robinson SM, Ordonez CL, Waltz DA, Riley MA.	Microbiology (Reading)	10.1099/mic.0.036848-0	2010
Phylogeny	PCR-based detection and identification of Burkholderia cepacia complex pathogens in sputum from cystic fibrosis patients.	McDowell A, Mahenthiralingam E, Moore JE, Dunbar KE, Webb AK, Dodd ME, Martin SL, Millar BC, Scott CJ, Crowe M, Elborn JS.	J Clin Microbiol	10.1128/jcm.39.12.4247-4255.2001	2001
Metabolism	Common duckweed (Lemna minor) is a versatile high-throughput infection model for the Burkholderia cepacia complex and other pathogenic bacteria.	Thomson EL, Dennis JJ, Dennis JJ.	PLoS One	10.1371/journal.pone.0080102	2013
Metabolism	Pseudomonas aeruginosa alginate promotes Burkholderia cenocepacia persistence in cystic fibrosis transmembrane conductance regulator knockout mice.	Chattoraj SS, Murthy R, Ganesan S, Goldberg JB, Zhao Y, Hershenson MB, Sajjan US.	Infect Immun	10.1128/iai.01192-09	2010
Phylogeny	Identification of Pandoraea species by 16S ribosomal DNA-based PCR assays.	Coenye T, Liu L, Vandamme P, LiPuma JJ.	J Clin Microbiol	10.1128/jcm.39.12.4452-4455.2001	2001
	In vitro analysis of ISEcp1B-mediated mobilization of naturally occurring beta-lactamase gene blaCTX-M of Kluyvera ascorbata.	Lartigue MF, Poirel L, Aubert D, Nordmann P.	Antimicrob Agents Chemother	10.1128/aac.50.4.1282-1286.2006	2006
Metabolism	A Burkholderia cepacia complex non-ribosomal peptide-synthesized toxin is hemolytic and required for full virulence.	Thomson EL, Dennis JJ.	Virulence	10.4161/viru.19355	2012
Enzymology	A single module type I polyketide synthase directs de novo macrolactone biogenesis during galbonolide biosynthesis in Streptomyces galbus.	Kim HJ, Karki S, Kwon SY, Park SH, Nahm BH, Kim YK, Kwon HJ.	J Biol Chem	10.1074/jbc.m114.602334	2014
Phylogeny	Molecular method to assess the diversity of Burkholderia species in environmental samples.	Salles JF, De Souza FA, van Elsas JD.	Appl Environ Microbiol	10.1128/aem.68.4.1595-1603.2002	2002
Enzymology	Insights into beta-lactamases from Burkholderia species, two phylogenetically related yet distinct resistance determinants.	Papp-Wallace KM, Taracila MA, Gatta JA, Ohuchi N, Bonomo RA, Nukaga M.	J Biol Chem	10.1074/jbc.m113.458315	2013
	Zinc-Induced Transposition of Insertion Sequence Elements Contributes to Increased Adaptability of Cupriavidus metallidurans.	Vandecraen J, Monsieurs P, Mergeay M, Leys N, Aertsen A, Van Houdt R.	Front Microbiol	10.3389/fmicb.2016.00359	2016
Genetics	Comparative Genomic Analysis of the Human Gut Microbiome Reveals a Broad Distribution of Metabolic Pathways for the Degradation of Host-Synthetized Mucin Glycans and Utilization of Mucin-Derived Monosaccharides.	Ravcheev DA, Thiele I.	Front Genet	10.3389/fgene.2017.00111	2017
Metabolism	Hopanoid production is required for low-pH tolerance, antimicrobial resistance, and motility in Burkholderia cenocepacia.	Schmerk CL, Bernards MA, Valvano MA.	J Bacteriol	10.1128/jb.05979-11	2011
Metabolism	Identification of novel regulatory small RNAs in Acinetobacter baumannii.	Sharma R, Arya S, Patil SD, Sharma A, Jain PK, Navani NK, Pathania R.	PLoS One	10.1371/journal.pone.0093833	2014
Metabolism	Identification of opsA, a gene involved in solute stress mitigation and survival in soil, in the polycyclic aromatic hydrocarbon-degrading bacterium Novosphingobium sp. strain LH128.	Fida TT, Breugelmans P, Lavigne R, van der Meer JR, De Mot R, Vaysse PJ, Springael D.	Appl Environ Microbiol	10.1128/aem.00306-14	2014
Enzymology	Highly sensitive real-time PCR for specific detection and quantification of Coxiella burnetii.	Klee SR, Tyczka J, Ellerbrok H, Franz T, Linke S, Baljer G, Appel B.	BMC Microbiol	10.1186/1471-2180-6-2	2006
Pathogenicity	Recent Progress in Natural-Product-Inspired Programs Aimed To Address Antibiotic Resistance and Tolerance.	Abouelhassan Y, Garrison AT, Yang H, Chavez-Riveros A, Burch GM, Huigens RW.	J Med Chem	10.1021/acs.jmedchem.9b00370	2019
	Use of suppression-subtractive hybridization to identify genes in the Burkholderia cepacia complex that are unique to Burkholderia cenocepacia.	Bernier SP, Sokol PA.	J Bacteriol	10.1128/jb.187.15.5278-5291.2005	2005
Pathogenicity	The antimicrobial efficacy of sustained release silver-carbene complex-loaded L-tyrosine polyphosphate nanoparticles: characterization, in vitro and in vivo studies.	Hindi KM, Ditto AJ, Panzner MJ, Medvetz DA, Han DS, Hovis CE, Hilliard JK, Taylor JB, Yun YH, Cannon CL, Youngs WJ.	Biomaterials	10.1016/j.biomaterials.2009.03.044	2009
Metabolism	Pathway and evolutionary implications of diphenylamine biodegradation by Burkholderia sp. strain JS667.	Shin KA, Spain JC.	Appl Environ Microbiol	10.1128/aem.02198-08	2009
Metabolism	Structure of Burkholderia cepacia UDP-glucose dehydrogenase (UGD) BceC and role of Tyr10 in final hydrolysis of UGD thioester intermediate.	Rocha J, Popescu AO, Borges P, Mil-Homens D, Moreira LM, Sa-Correia I, Fialho AM, Frazao C.	J Bacteriol	10.1128/jb.01076-10	2011
Metabolism	Identification of elongation factor G as the conserved cellular target of argyrin B.	Nyfeler B, Hoepfner D, Palestrant D, Kirby CA, Whitehead L, Yu R, Deng G, Caughlan RE, Woods AL, Jones AK, Barnes SW, Walker JR, Gaulis S, Hauy E, Brachmann SM, Krastel P, Studer C, Riedl R, Estoppey D, Aust T, Movva NR, Wang Z, Salcius M, Michaud GA, McAllister G, Murphy LO, Tallarico JA, Wilson CJ, Dean CR.	PLoS One	10.1371/journal.pone.0042657	2012
	Burkholderia cenocepacia phenotypic clonal variation during a 3.5-year colonization in the lungs of a cystic fibrosis patient.	Coutinho CP, de Carvalho CC, Madeira A, Pinto-de-Oliveira A, Sa-Correia I.	Infect Immun	10.1128/iai.01366-10	2011
Metabolism	Conjugal transfer of polychlorinated biphenyl/biphenyl degradation genes in Acidovorax sp. strain KKS102, which are located on an integrative and conjugative element.	Ohtsubo Y, Ishibashi Y, Naganawa H, Hirokawa S, Atobe S, Nagata Y, Tsuda M.	J Bacteriol	10.1128/jb.00352-12	2012
Phylogeny	Presence of a family of plasmids (29 to 65 kilobases) with a 26-kilobase common region in different strains of the sulfur-oxidizing bacterium Acidithiobacillus caldus.	van Zyl LJ, Deane SM, Louw LA, Rawlings DE.	Appl Environ Microbiol	10.1128/aem.00864-08	2008
	Tangled bank of experimentally evolved Burkholderia biofilms reflects selection during chronic infections.	Traverse CC, Mayo-Smith LM, Poltak SR, Cooper VS.	Proc Natl Acad Sci U S A	10.1073/pnas.1207025110	2013
Metabolism	A membrane-located glycosyltransferase complex required for biosynthesis of the D-galactan I lipopolysaccharide O antigen in Klebsiella pneumoniae.	Kos V, Whitfield C.	J Biol Chem	10.1074/jbc.m110.122598	2010
Genetics	The complete multipartite genome sequence of Cupriavidus necator JMP134, a versatile pollutant degrader.	Lykidis A, Perez-Pantoja D, Ledger T, Mavromatis K, Anderson IJ, Ivanova NN, Hooper SD, Lapidus A, Lucas S, Gonzalez B, Kyrpides NC.	PLoS One	10.1371/journal.pone.0009729	2010
Metabolism	Multiple controls affect arsenite oxidase gene expression in Herminiimonas arsenicoxydans.	Koechler S, Cleiss-Arnold J, Proux C, Sismeiro O, Dillies MA, Goulhen-Chollet F, Hommais F, Lievremont D, Arsene-Ploetze F, Coppee JY, Bertin PN.	BMC Microbiol	10.1186/1471-2180-10-53	2010
Metabolism	Elucidation of the regulon and cis-acting regulatory element of HrpB, the AraC-type regulator of a plant pathogen-like type III secretion system in Burkholderia pseudomallei.	Lipscomb L, Schell MA.	J Bacteriol	10.1128/jb.01379-10	2011
	T2R38 taste receptor polymorphisms underlie susceptibility to upper respiratory infection.	Lee RJ, Xiong G, Kofonow JM, Chen B, Lysenko A, Jiang P, Abraham V, Doghramji L, Adappa ND, Palmer JN, Kennedy DW, Beauchamp GK, Doulias PT, Ischiropoulos H, Kreindler JL, Reed DR, Cohen NA.	J Clin Invest	10.1172/jci64240	2012
	Burkholderia mallei expresses a unique lipopolysaccharide mixture that is a potent activator of human Toll-like receptor 4 complexes.	Brett PJ, Burtnick MN, Snyder DS, Shannon JG, Azadi P, Gherardini FC.	Mol Microbiol	10.1111/j.1365-2958.2006.05519.x	2007
	Hybrid pathogenicity island PAGI-5 contributes to the highly virulent phenotype of a Pseudomonas aeruginosa isolate in mammals.	Battle SE, Meyer F, Rello J, Kung VL, Hauser AR.	J Bacteriol	10.1128/jb.00785-08	2008
Enzymology	16S rRNA gene sequencing versus the API 20 NE system and the VITEK 2 ID-GNB card for identification of nonfermenting Gram-negative bacteria in the clinical laboratory.	Bosshard PP, Zbinden R, Abels S, Boddinghaus B, Altwegg M, Bottger EC.	J Clin Microbiol	10.1128/jcm.44.4.1359-1366.2006	2006
Metabolism	Molecular and culture-based analyses of aerobic carbon monoxide oxidizer diversity.	King GM.	Appl Environ Microbiol	10.1128/aem.69.12.7257-7265.2003	2003
Enzymology	Comparative evaluation of the BD Phoenix and VITEK 2 automated instruments for identification of isolates of the Burkholderia cepacia complex.	Brisse S, Stefani S, Verhoef J, Van Belkum A, Vandamme P, Goessens W.	J Clin Microbiol	10.1128/jcm.40.5.1743-1748.2002	2002
Metabolism	Roles of long and short replication initiation proteins in the fate of IncP-1 plasmids.	Yano H, Deckert GE, Rogers LM, Top EM.	J Bacteriol	10.1128/jb.06395-11	2012
	Genetic and phenotypic diversity in Burkholderia: contributions by prophage and phage-like elements.	Ronning CM, Losada L, Brinkac L, Inman J, Ulrich RL, Schell M, Nierman WC, Deshazer D.	BMC Microbiol	10.1186/1471-2180-10-202	2010
Metabolism	The Vein Patterning 1 (VEP1) gene family laterally spread through an ecological network.	Tarrio R, Ayala FJ, Rodriguez-Trelles F.	PLoS One	10.1371/journal.pone.0022279	2011
Metabolism	Diversity and evolution of the phenazine biosynthesis pathway.	Mavrodi DV, Peever TL, Mavrodi OV, Parejko JA, Raaijmakers JM, Lemanceau P, Mazurier S, Heide L, Blankenfeldt W, Weller DM, Thomashow LS.	Appl Environ Microbiol	10.1128/aem.02009-09	2010
	Patterns of epithelial cell invasion by different species of the Burkholderia cepacia complex in well-differentiated human airway epithelia.	Schwab U, Leigh M, Ribeiro C, Yankaskas J, Burns K, Gilligan P, Sokol P, Boucher R.	Infect Immun	10.1128/iai.70.8.4547-4555.2002	2002
Phylogeny	Multilocus sequence typing scheme that provides both species and strain differentiation for the Burkholderia cepacia complex.	Baldwin A, Mahenthiralingam E, Thickett KM, Honeybourne D, Maiden MC, Govan JR, Speert DP, Lipuma JJ, Vandamme P, Dowson CG.	J Clin Microbiol	10.1128/jcm.43.9.4665-4673.2005	2005
	Gene expression changes linked to antimicrobial resistance, oxidative stress, iron depletion and retained motility are observed when Burkholderia cenocepacia grows in cystic fibrosis sputum.	Drevinek P, Holden MT, Ge Z, Jones AM, Ketchell I, Gill RT, Mahenthiralingam E.	BMC Infect Dis	10.1186/1471-2334-8-121	2008
	Correlation of rpsU Gene Sequence Clusters and Biochemical Properties, Gc-Ms Spectra and Resistance Profiles of Clinical Burkholderia Spp. Isolates.	Ostermann MF, Neubauer H, Frickmann H, Hagen RM.	Eur J Microbiol Immunol (Bp)	10.1556/1886.2016.00002	2016
Enzymology	Evolution of bacterial phosphoglycerate mutases: non-homologous isofunctional enzymes undergoing gene losses, gains and lateral transfers.	Foster JM, Davis PJ, Raverdy S, Sibley MH, Raleigh EA, Kumar S, Carlow CK.	PLoS One	10.1371/journal.pone.0013576	2010
Phylogeny	characterization of bacterial community diversity in cystic fibrosis lung infections by use of 16s ribosomal DNA terminal restriction fragment length polymorphism profiling.	Rogers GB, Carroll MP, Serisier DJ, Hockey PM, Jones G, Bruce KD.	J Clin Microbiol	10.1128/jcm.42.11.5176-5183.2004	2004
Enzymology	Bacterial diversity in cases of lung infection in cystic fibrosis patients: 16S ribosomal DNA (rDNA) length heterogeneity PCR and 16S rDNA terminal restriction fragment length polymorphism profiling.	Rogers GB, Hart CA, Mason JR, Hughes M, Walshaw MJ, Bruce KD.	J Clin Microbiol	10.1128/jcm.41.8.3548-3558.2003	2003
	The Burkholderia bcpAIOB genes define unique classes of two-partner secretion and contact dependent growth inhibition systems.	Anderson MS, Garcia EC, Cotter PA.	PLoS Genet	10.1371/journal.pgen.1002877	2012
Genetics	Comparative genomics reveals diversity among xanthomonads infecting tomato and pepper.	Potnis N, Krasileva K, Chow V, Almeida NF, Patil PB, Ryan RP, Sharlach M, Behlau F, Dow JM, Momol M, White FF, Preston JF, Vinatzer BA, Koebnik R, Setubal JC, Norman DJ, Staskawicz BJ, Jones JB.	BMC Genomics	10.1186/1471-2164-12-146	2011
	Population-specific gene expression in the plant pathogenic nematode Heterodera glycines exists prior to infection and during the onset of a resistant or susceptible reaction in the roots of the Glycine max genotype Peking.	Klink VP, Hosseini P, MacDonald MH, Alkharouf NW, Matthews BF.	BMC Genomics	10.1186/1471-2164-10-111	2009
	Role of ornibactin biosynthesis in the virulence of Burkholderia cepacia: characterization of pvdA, the gene encoding L-ornithine N(5)-oxygenase.	Sokol PA, Darling P, Woods DE, Mahenthiralingam E, Kooi C.	Infect Immun	10.1128/iai.67.9.4443-4455.1999	1999
Metabolism	Polymorphic toxin systems: Comprehensive characterization of trafficking modes, processing, mechanisms of action, immunity and ecology using comparative genomics.	Zhang D, de Souza RF, Anantharaman V, Iyer LM, Aravind L.	Biol Direct	10.1186/1745-6150-7-18	2012
Metabolism	Conservation of the opcL gene encoding the peptidoglycan-associated outer-membrane lipoprotein among representatives of the Burkholderia cepacia complex.	Plesa M, Kholti A, Vermis K, Vandamme P, Panagea S, Winstanley C, Cornelis P	J Med Microbiol	10.1099/jmm.0.05504-0	2004
Phylogeny	Proposal to accommodate Burkholderia cepacia genomovar VI as Burkholderia dolosa sp. nov.	Vermis K, Coenye T, LiPuma JJ, Mahenthiralingam E, Nelis HJ, Vandamme P.	Int J Syst Evol Microbiol	10.1099/ijs.0.02888-0	2004
Phylogeny	Occurrence of multiple genomovars of Burkholderia cepacia in cystic fibrosis patients and proposal of Burkholderia multivorans sp. nov.	Vandamme P, Holmes B, Vancanneyt M, Coenye T, Hoste B, Coopman R, Revets H, Lauwers S, Gillis M, Kersters K, Govan JR.	Int J Syst Bacteriol	10.1099/00207713-47-4-1188	1997
Phylogeny	Burkholderia ambifaria sp. nov., a novel member of the Burkholderia cepacia complex including biocontrol and cystic fibrosis-related isolates.	Coenye T, Mahenthiralingam E, Henry D, LiPuma JJ, Laevens S, Gillis M, Speert DP, Vandamme P.	Int J Syst Evol Microbiol	10.1099/00207713-51-4-1481	2001

References

#4980	Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 13243
#20215	Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 )
#20218	Verslyppe, B., De Smet, W., De Baets, B., De Vos, P., Dawyndt P.: StrainInfo introduces electronic passports for microorganisms.. Syst Appl Microbiol. 37: 42 - 50 2014 ( DOI 10.1016/j.syapm.2013.11.002 , PubMed 24321274 )
#35830	; Curators of the CIP;
#51924	Culture Collection University of Gothenburg (CCUG) ; Curators of the CCUG; CCUG 34080
#66792	Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) .
#68369	Automatically annotated from API 20NE .
#68382	Automatically annotated from API zym .
#121175	Collection of Institut Pasteur ; Curators of the CIP; CIP 105495
#124043	Isabel Schober, Julia Koblitz: Data extracted from sequence databases, automatically matched based on designation and taxonomy .
#125438	Julia Koblitz, Lorenz Christian Reimer, Rüdiger Pukall, Jörg Overmann: Predicting bacterial phenotypic traits through improved machine learning using high-quality, curated datasets. 2024 ( DOI 10.1101/2024.08.12.607695 )
#125439	Philipp Münch, René Mreches, Martin Binder, Hüseyin Anil Gündüz, Xiao-Yin To, Alice McHardy: deepG: Deep Learning for Genome Sequence Data. R package version 0.3.1 .
#126262	A. Lissin, I. Schober, J. F. Witte, H. Lüken, A. Podstawka, J. Koblitz, B. Bunk, P. Dawyndt, P. Vandamme, P. de Vos, J. Overmann, L. C. Reimer: StrainInfo—the central database for linked microbial strain identifiers. ( DOI 10.1093/database/baaf059 )

Rate our new design

Content

About us

Burkholderia multivorans (DSM 13243, CIP 105495, LMG 13010)

Name and taxonomic classification

Morphology

Cell morphology

Colony morphology

Pigmentation

Culture and growth conditions

Culture medium

Culture temp

Physiology and metabolism

Oxygen tolerance

Spore formation

Halophily

Metabolite utilization

Antibiotic resistance

Metabolite production

Metabolite tests

Enzymes

API zym

API 20NE

API biotype100

Isolation, sampling and environmental information

Isolation source categories

Isolation

Interaction and safety

Risk assessment

Sequence information

Genome sequences

Genome browser: GCA_900446205

16S sequences

Genome-based predictions

Predictions

Literature

Literature

References

BacDive

Help

Social Media