Archaeoglobus fulgidus (DSM 4304, ATCC 49558, JCM 9628)

Name: Archaeoglobus fulgidus (DSM 4304, ATCC 49558, JCM 9628)
Creator: BacDive
License: http://creativecommons.org/licenses/by/4.0/

BacDive ID 18096

Type strain

Strain Designation VC-16

Culture col. no. DSM 4304 ATCC 49558 JCM 9628 NBRC 100126 VC-16

NCBI tax ID(s) 224325 2234

Special Collections DSMZ JCM

History <- K.O. Stetter, VC-16 DSM 4304 <-- K. O. Stetter VC-16.

Links

Archaeoglobus fulgidus VC-16 is an anaerobe archaeon that was isolated from submarine hot spring.

anaerobe genome sequence 16S sequence Archaea

Name and taxonomic classification

SI-ID 46110

ATCC 49558,DSM 4304,ATCC 49203,JCM 9628,NBRC 100126

@ref 20215

Last LPSN update 2026-02-09 11:22:22

Domain Archaea

Phylum Methanobacteriota

Class Archaeoglobi

Order Archaeoglobales

Family Archaeoglobaceae

Genus Archaeoglobus

Species Archaeoglobus fulgidus

Full scientific name Archaeoglobus fulgidus Stetter 1988

BacDive ID	Other strains from **Archaeoglobus fulgidus** (2)	Type strain
18095	A. fulgidus Z, DSM 4139
132693	A. fulgidus 7324, DSM 8774

Morphology

Cell morphology

@ref	Motility	Confidence
125439		91.4

Culture and growth conditions

Culture medium

@ref	Name	Growth	Medium link	Composition
1648	ARCHAEOGLOBUS MEDIUM (DSMZ Medium 399)		Medium recipe at MediaDive	Name: ARCHAEOGLOBUS MEDIUM (DSMZ Medium 399) Composition: MgCl2 x 6 H2O 3.95257 g/l NaHCO3 2.96443 g/l Na-L-lactate 1.48221 g/l Na2S x 9 H2O 0.494071 g/l Yeast extract 0.494071 g/l KCl 0.335968 g/l NH4Cl 0.247036 g/l K2HPO4 0.13834 g/l MgSO4 x 7 H2O 0.0296443 g/l Nitrilotriacetic acid 0.0148221 g/l NaCl 0.00988142 g/l MnSO4 x H2O 0.00494071 g/l Fe(NH4)2(SO4)2 x 7 H2O 0.00197628 g/l CoSO4 x 7 H2O 0.00177866 g/l ZnSO4 x 7 H2O 0.00177866 g/l FeSO4 x 7 H2O 0.000988142 g/l CaCl2 x 2 H2O 0.000988142 g/l Sodium resazurin 0.000494071 g/l NiCl2 x 6 H2O 0.000296443 g/l AlK(SO4)2 x 12 H2O 0.000197628 g/l CuSO4 x 5 H2O 9.88142e-05 g/l Na2MoO4 x 2 H2O 9.88142e-05 g/l H3BO3 9.88142e-05 g/l Na2WO4 x 2 H2O 3.95257e-06 g/l Na2SeO3 x 5 H2O 2.96443e-06 g/l Distilled water

Culture temp

@ref	Growth	Type	Temperature (°C)
1648	positive	growth	85
67770	positive	growth	80

Physiology and metabolism

Oxygen tolerance

@ref	Oxygen tolerance	Confidence
1648	anaerobe
125439	facultative anaerobe	90.1

Spore formation

@ref	Spore formation	Confidence
125439		95.8

Compound production

1648

Compoundisocitrate dehydrogenase

Observation

67770

Observationquinones: MK-7(H₁₄)

Pathway annotation

Computationally determined by

@ref	pathway	enzyme coverage	annotated reactions
66794	suberin monomers biosynthesis	100	2 of 2
66794	adipate degradation	100	2 of 2
66794	coenzyme A metabolism	100	4 of 4
66794	hydrogen production	100	5 of 5
66794	methanofuran biosynthesis	100	5 of 5
66794	ubiquinone biosynthesis	100	7 of 7
66794	ribulose monophosphate pathway	100	2 of 2
66794	factor 420 biosynthesis	100	5 of 5
66794	methylglyoxal degradation	100	5 of 5
66794	anapleurotic synthesis of oxalacetate	100	1 of 1
66794	palmitate biosynthesis	100	22 of 22
66794	UDP-GlcNAc biosynthesis	100	3 of 3
66794	aspartate and asparagine metabolism	88.89	8 of 9
66794	chorismate metabolism	88.89	8 of 9
66794	CO2 fixation in Crenarchaeota	88.89	8 of 9
66794	gluconeogenesis	87.5	7 of 8
66794	propanol degradation	85.71	6 of 7
66794	methanogenesis from CO2	83.33	10 of 12
66794	flavin biosynthesis	80	12 of 15
66794	photosynthesis	78.57	11 of 14
66794	valine metabolism	77.78	7 of 9
66794	molybdenum cofactor biosynthesis	77.78	7 of 9
66794	vitamin B1 metabolism	76.92	10 of 13
66794	phenylalanine metabolism	76.92	10 of 13
66794	vitamin B12 metabolism	76.47	26 of 34
66794	isoleucine metabolism	75	6 of 8
66794	C4 and CAM-carbon fixation	75	6 of 8
66794	NAD metabolism	72.22	13 of 18
66794	glutamate and glutamine metabolism	71.43	20 of 28
66794	lipid metabolism	70.97	22 of 31
66794	propionate fermentation	70	7 of 10
66794	4-hydroxyphenylacetate degradation	70	7 of 10
66794	sulfate reduction	69.23	9 of 13
66794	acetoin degradation	66.67	2 of 3
66794	octane oxidation	66.67	2 of 3
66794	formaldehyde oxidation	66.67	2 of 3
66794	serine metabolism	66.67	6 of 9
66794	L-lactaldehyde degradation	66.67	2 of 3
66794	methane metabolism	66.67	2 of 3
66794	purine metabolism	65.96	62 of 94
66794	alanine metabolism	65.52	19 of 29
66794	glycolysis	64.71	11 of 17
66794	pyrimidine metabolism	64.44	29 of 45
66794	heme metabolism	64.29	9 of 14
66794	oxidative phosphorylation	63.74	58 of 91
66794	6-hydroxymethyl-dihydropterin diphosphate biosynthesis	62.5	5 of 8
66794	arginine metabolism	62.5	15 of 24
66794	leucine metabolism	61.54	8 of 13
66794	urea cycle	61.54	8 of 13
66794	threonine metabolism	60	6 of 10
66794	phenylacetate degradation (aerobic)	60	3 of 5
66794	vitamin K metabolism	60	3 of 5
66794	lysine metabolism	59.52	25 of 42
66794	reductive acetyl coenzyme A pathway	57.14	4 of 7
66794	citric acid cycle	57.14	8 of 14
66794	polyamine pathway	56.52	13 of 23
66794	nitrate assimilation	55.56	5 of 9
66794	d-mannose degradation	55.56	5 of 9
66794	non-pathway related	55.26	21 of 38
66794	pentose phosphate pathway	54.55	6 of 11
66794	histidine metabolism	51.72	15 of 29
66794	lactate fermentation	50	2 of 4
66794	ethanol fermentation	50	1 of 2
66794	toluene degradation	50	2 of 4
66794	cis-vaccenate biosynthesis	50	1 of 2
66794	aminopropanol phosphate biosynthesis	50	1 of 2
66794	dolichol and dolichyl phosphate biosynthesis	50	1 of 2
66794	1,4-dihydroxy-6-naphthoate biosynthesis	50	3 of 6
66794	Entner Doudoroff pathway	50	5 of 10
66794	CDP-diacylglycerol biosynthesis	50	1 of 2
66794	pantothenate biosynthesis	50	3 of 6
66794	sulfopterin metabolism	50	2 of 4
66794	glycolate and glyoxylate degradation	50	3 of 6
66794	acetate fermentation	50	2 of 4
66794	glycogen biosynthesis	50	2 of 4
66794	butanoate fermentation	50	2 of 4
66794	degradation of aromatic, nitrogen containing compounds	50	6 of 12
66794	phenylmercury acetate degradation	50	1 of 2
66794	selenocysteine biosynthesis	50	3 of 6
66794	quinate degradation	50	1 of 2
66794	glycine metabolism	50	5 of 10
66794	isoprenoid biosynthesis	50	13 of 26
66794	methionine metabolism	50	13 of 26
66794	tryptophan metabolism	47.37	18 of 38
66794	proline metabolism	45.45	5 of 11
66794	glutathione metabolism	42.86	6 of 14
66794	cardiolipin biosynthesis	42.86	3 of 7
66794	tyrosine metabolism	42.86	6 of 14
66794	arachidonate biosynthesis	40	2 of 5
66794	coenzyme M biosynthesis	40	4 of 10
66794	elloramycin biosynthesis	40	2 of 5
66794	myo-inositol biosynthesis	40	4 of 10
66794	ethylmalonyl-CoA pathway	40	2 of 5
66794	degradation of hexoses	38.89	7 of 18
66794	carnitine metabolism	37.5	3 of 8
66794	ketogluconate metabolism	37.5	3 of 8
66794	degradation of pentoses	35.71	10 of 28
66794	cyanate degradation	33.33	1 of 3
66794	sphingosine metabolism	33.33	2 of 6
66794	acetyl CoA biosynthesis	33.33	1 of 3
66794	lipid A biosynthesis	33.33	3 of 9
66794	cysteine metabolism	33.33	6 of 18
66794	enterobactin biosynthesis	33.33	1 of 3
66794	IAA biosynthesis	33.33	1 of 3
66794	benzoyl-CoA degradation	28.57	2 of 7
66794	mevalonate metabolism	28.57	2 of 7
66794	tetrahydrofolate metabolism	28.57	4 of 14
66794	chlorophyll metabolism	27.78	5 of 18
66794	vitamin B6 metabolism	27.27	3 of 11
66794	metabolism of disaccharids	27.27	3 of 11
66794	dolichyl-diphosphooligosaccharide biosynthesis	27.27	3 of 11
66794	cholesterol biosynthesis	27.27	3 of 11
66794	cyclohexanol degradation	25	1 of 4
66794	biotin biosynthesis	25	1 of 4
66794	vitamin E metabolism	25	1 of 4
66794	alginate biosynthesis	25	1 of 4
66794	dTDPLrhamnose biosynthesis	25	2 of 8
66794	CMP-KDO biosynthesis	25	1 of 4
66794	catecholamine biosynthesis	25	1 of 4
66794	ppGpp biosynthesis	25	1 of 4
66794	degradation of sugar acids	24	6 of 25
66794	phosphatidylethanolamine bioynthesis	23.08	3 of 13
66794	4-hydroxymandelate degradation	22.22	2 of 9

Isolation, sampling and environmental information

Isolation source categories

Cat1	Cat2	Cat3
#Environmental	#Aquatic	#Marine
#Environmental	#Aquatic	#Thermal spring
#Condition	#Thermophilic (>45°C)	-

Isolation

@ref	Sample type	Geographic location	Country	Country ISO 3 Code	Continent
1648	submarine hot spring	Vulcano island	Italy	ITA	Europe
67770	Hot sediments of marine hydrothermal system	Vulcano	Italy	ITA	Europe

Taxonmaps

69479

Global distribution of 16S sequence Y00275 (>99% sequence identity) for Archaeoglobus fulgidus subclade from Microbeatlas

Aquatic Samples	91
Soil Samples	3
Animal Samples	1
Plant Samples
Total Samples	95

Interaction and safety

Risk assessment

@ref	Biosafety level	Biosafety level comment
1648	1	Risk group (German classification) According to TRBA 466

Sequence information

Genome sequences

@ref	Description	Assembly level	INSDC accession	BV-BRC accession	IMG accession	NCBI tax ID	Score
66792	ASM866v1 assembly for Archaeoglobus fulgidus DSM 4304	complete	GCA_000008665	224325.10	638154502	224325	97.81

16S sequences

@ref	Description	Accession	Length	Database	NCBI tax ID
67770	Archaeoglobus fulgidus strain VC-16 16S ribosomal RNA gene	X05567	1492		224325
67770	Archaeoglobus fulgidus (VC-16) DNA for 16S ribosomal RNA	Y00275	1492		224325

GC content

@ref	GC-content (mol%)	Method
1648	46.0
67770	46	thermal denaturation, midpoint method (Tm)

Genome-based predictions

Predictions

Predictions from Deep Learning for Genome Sequence Data. R package version 0.3.1 based on: Archaeoglobus fulgidus DSM 4304
NCBI: GCA_000008665

@ref	Trait	Model	Prediction	Confidence in %	In training data
125439	spore_formation	BacteriaNetⓘ	yes	95.80	no
125439	motility	BacteriaNetⓘ	yes	91.40	no
125439	gram_stain	BacteriaNetⓘ	variable	88.90	no
125439	oxygen_tolerance	BacteriaNetⓘ	facultative anaerobe	90.10	no

Predictions from bacterial phenotypic traits through improved machine learning using high-quality, curated datasets based on: Archaeoglobus fulgidus DSM 4304 DSM 4304
NCBI: GCA_000008665.1

@ref	Trait	Model	Prediction	Confidence in %	In training data
125438	gram-positive	gram-positiveⓘ	no	65.94	no
125438	anaerobic	anaerobicⓘ	yes	85.87	yes
125438	aerobic	aerobicⓘ	no	81.90	no
125438	spore-forming	spore-formingⓘ	no	85.08	no
125438	thermophilic	thermophileⓘ	yes	70.24	yes
125438	flagellated	motile2+ⓘ	no	86.71	no

Literature

Topic	Title	Authors	Journal	DOI	Year
	Francisella tularensis universal stress protein contributes to persistence during growth arrest and paraquat-induced superoxide stress.	Girardo B, Yue Y, Lockridge O, Bartling AM, Schopfer LM, Augusto L, Larson MA.	J Bacteriol	10.1128/jb.00377-24	2025
	The missing part: the Archaeoglobus fulgidus Argonaute forms a functional heterodimer with an N-L1-L2 domain protein.	Manakova E, Golovinas E, Poceviciute R, Sasnauskas G, Silanskas A, Rutkauskas D, Jankunec M, Zagorskaite E, Jurgelaitis E, Grybauskas A, Venclovas C, Zaremba M.	Nucleic Acids Res	10.1093/nar/gkad1241	2024
	Structural basis for sequence-specific recognition of guide and target strands by the Archaeoglobus fulgidus Argonaute protein.	Manakova E, Golovinas E, Poceviciute R, Sasnauskas G, Grybauskas A, Grazulis S, Zaremba M.	Sci Rep	10.1038/s41598-023-32600-w	2023
	Tat-fimbriae ("tafi"): An unusual type of haloarchaeal surface structure depending on the twin-arginine translocation pathway.	Galeva AV, Zhao D, Syutkin AS, Topilina MY, Shchyogolev SY, Pavlova EY, Selivanova OM, Kireev II, Surin AK, Burygin GL, Liu J, Xiang H, Pyatibratov MG.	iScience	10.1016/j.isci.2025.111793	2025
Enzymology	Biochemical Characterization of Recombinant Isocitrate Dehydrogenase and Its Putative Role in the Physiology of an Acidophilic Micrarchaeon.	Winkler D, Gfrerer S, Gescher J.	Microorganisms	10.3390/microorganisms9112318	2021
	An AlphaFold Structure Analysis of COQ2 as Key a Component of the Coenzyme Q Synthesis Complex.	Vargas-Perez MLA, Devos DP, Lopez-Lluch G.	Antioxidants (Basel)	10.3390/antiox13040496	2024
Genetics	Metabolic profiling of petroleum-degrading microbial communities incubated under high-pressure conditions.	Xu J, Wang L, Lv W, Song X, Nie Y, Wu XL.	Front Microbiol	10.3389/fmicb.2023.1305731	2023
	Characterizing the Piezosphere: The Effects of Decompression on Microbial Growth Dynamics.	Cario A, Oliver GC, Rogers KL.	Front Microbiol	10.3389/fmicb.2022.867340	2022
	Assimilatory sulfate reduction in the marine methanogen Methanothermococcus thermolithotrophicus.	Jespersen M, Wagner T.	Nat Microbiol	10.1038/s41564-023-01398-8	2023
Enzymology	A Reduced F₄₂₀-Dependent Nitrite Reductase in an Anaerobic Methanotrophic Archaeon.	Heryakusuma C, Susanti D, Yu H, Li Z, Purwantini E, Hettich RL, Orphan VJ, Mukhopadhyay B.	J Bacteriol	10.1128/jb.00078-22	2022
Enzymology	DsrMKJOP is the terminal reductase complex in anaerobic sulfate respiration.	Barbosa ACC, Venceslau SS, Pereira IAC.	Proc Natl Acad Sci U S A	10.1073/pnas.2313650121	2024
Metabolism	Development of a Novel Cell Surface Attachment System to Display Multi-Protein Complex Using the Cohesin-Dockerin Binding Pair.	Ko HJ, Song H, Choi IG.	J Microbiol Biotechnol	10.4014/jmb.2105.05022	2021
	A novel methoxydotrophic metabolism discovered in the hyperthermophilic archaeon Archaeoglobus fulgidus.	Welte CU, de Graaf R, Dalcin Martins P, Jansen RS, Jetten MSM, Kurth JM.	Environ Microbiol	10.1111/1462-2920.15546	2021
Metabolism	Data on the optimization of an archaea-specific probe-based qPCR assay.	Bomberg M, Miettinen H.	Data Brief	10.1016/j.dib.2020.106610	2020
Genetics	Shotgun Metagenomics-Guided Prediction Reveals the Metal Tolerance and Antibiotic Resistance of Microbes in Poly-Extreme Environments in the Danakil Depression, Afar Region.	Balcha ES, Gomez F, Gemeda MT, Bekele FB, Abera S, Cavalazzi B, Woldesemayat AA.	Antibiotics (Basel)	10.3390/antibiotics12121697	2023
Enzymology	Molecular Characterization of the Iron-Containing Alcohol Dehydrogenase from the Extremely Thermophilic Bacterium Pseudothermotoga hypogea.	Hao L, Ayinla Z, Ma K.	Microorganisms	10.3390/microorganisms12020311	2024
	Complete genome sequence analysis of Archaeoglobus fulgidus strain 7324 (DSM 8774), a hyperthermophilic archaeal sulfate reducer from a North Sea oil field.	Birkeland NK, Schonheit P, Poghosyan L, Fiebig A, Klenk HP.	Stand Genomic Sci	10.1186/s40793-017-0296-5	2017
Genetics	A new statistic for efficient detection of repetitive sequences.	Chen S, Chen Y, Sun F, Waterman MS, Zhang X.	Bioinformatics	10.1093/bioinformatics/btz262	2019
Genetics	Metagenome reveals potential microbial degradation of hydrocarbon coupled with sulfate reduction in an oil-immersed chimney from Guaymas Basin.	He Y, Xiao X, Wang F.	Front Microbiol	10.3389/fmicb.2013.00148	2013
Enzymology	Genomic and Transcriptomic Evidence Supports Methane Metabolism in Archaeoglobi.	Liu YF, Chen J, Zaramela LS, Wang LY, Mbadinga SM, Hou ZW, Wu XL, Gu JD, Zengler K, Mu BZ.	mSystems	10.1128/msystems.00651-19	2020
Enzymology	Birth of Archaeal Cells: Molecular Phylogenetic Analyses of G1P Dehydrogenase, G3P Dehydrogenases, and Glycerol Kinase Suggest Derived Features of Archaeal Membranes Having G1P Polar Lipids.	Yokobori SI, Nakajima Y, Akanuma S, Yamagishi A.	Archaea	10.1155/2016/1802675	2016
Metabolism	The structure of an archaeal oligosaccharyltransferase provides insight into the strict exclusion of proline from the N-glycosylation sequon.	Taguchi Y, Yamasaki T, Ishikawa M, Kawasaki Y, Yukimura R, Mitani M, Hirata K, Kohda D.	Commun Biol	10.1038/s42003-021-02473-8	2021
Phylogeny	Application of denaturing high-performance liquid chromatography for monitoring sulfate-reducing bacteria in oil fields.	Priha O, Nyyssonen M, Bomberg M, Laitila A, Simell J, Kapanen A, Juvonen R.	Appl Environ Microbiol	10.1128/aem.01015-13	2013
	Survival and Energy Producing Strategies of Alkane Degraders Under Extreme Conditions and Their Biotechnological Potential.	Park C, Park W.	Front Microbiol	10.3389/fmicb.2018.01081	2018
Genetics	P finder: genomic and metagenomic annotation of RNase P RNA gene (rnpB).	Ellis JC.	BMC Genomics	10.1186/s12864-020-6615-z	2020
Enzymology	Structural basis for catalysis in a CDP-alcohol phosphotransferase.	Sciara G, Clarke OB, Tomasek D, Kloss B, Tabuso S, Byfield R, Cohn R, Banerjee S, Rajashankar KR, Slavkovic V, Graziano JH, Shapiro L, Mancia F.	Nat Commun	10.1038/ncomms5068	2014
	Distribution of Peptidyl-Prolyl Isomerase (PPIase) in the Archaea.	Anchal, Kaushik V, Goel M.	Front Microbiol	10.3389/fmicb.2021.751049	2021
Enzymology	Comprehensive mutagenesis to identify amino acid residues contributing to the difference in thermostability between two originally thermostable ancestral proteins.	Akanuma S, Yamaguchi M, Yamagishi A.	PLoS One	10.1371/journal.pone.0258821	2021
Metabolism	The ARH and Macrodomain Families of alpha-ADP-ribose-acceptor Hydrolases Catalyze alpha-NAD⁺ Hydrolysis.	Stevens LA, Kato J, Kasamatsu A, Oda H, Lee DY, Moss J.	ACS Chem Biol	10.1021/acschembio.9b00429	2019
	Crystal structures of CRISPR-associated Csx3 reveal a manganese-dependent deadenylation exoribonuclease.	Yan X, Guo W, Yuan YA.	RNA Biol	10.1080/15476286.2015.1051300	2015
Metabolism	Anaerobic oxidation of fatty acids and alkenes by the hyperthermophilic sulfate-reducing archaeon Archaeoglobus fulgidus.	Khelifi N, Grossi V, Hamdi M, Dolla A, Tholozan JL, Ollivier B, Hirschler-Rea A.	Appl Environ Microbiol	10.1128/aem.02810-09	2010
Metabolism	The DsrD functional marker protein is an allosteric activator of the DsrAB dissimilatory sulfite reductase.	Ferreira D, Barbosa ACC, Oliveira GP, Catarino T, Venceslau SS, Pereira IAC.	Proc Natl Acad Sci U S A	10.1073/pnas.2118880119	2022
Metabolism	Metabolic Adaptation to Sulfur of Hyperthermophilic Palaeococcus pacificus DY20341^T from Deep-Sea Hydrothermal Sediments.	Zeng X, Zhang X, Shao Z.	Int J Mol Sci	10.3390/ijms21010368	2020
Genetics	Species-resolved, single-cell respiration rates reveal dominance of sulfate reduction in a deep continental subsurface ecosystem.	Lindsay MR, D'Angelo T, Munson-McGee JH, Saidi-Mehrabad A, Devlin M, McGonigle J, Goodell E, Herring M, Lubelczyk LC, Mascena C, Brown JM, Gavelis G, Liu J, Yousavich DJ, Hamilton-Brehm SD, Hedlund BP, Lang S, Treude T, Poulton NJ, Stepanauskas R, Moser DP, Emerson D, Orcutt BN.	Proc Natl Acad Sci U S A	10.1073/pnas.2309636121	2024
Phylogeny	Reconstructing Phylogeny by Aligning Multiple Metabolic Pathways Using Functional Module Mapping.	Huang Y, Zhong C, Lin HX, Wang J, Peng Y.	Molecules	10.3390/molecules23020486	2018
	Crystallization and preliminary X-ray analysis of a cohesin-like module from AF2375 of the archaeon Archaeoglobus fulgidus.	Voronov-Goldman M, Noach I, Lamed R, Shimon LJ, Borovok I, Bayer EA, Frolow F.	Acta Crystallogr Sect F Struct Biol Cryst Commun	10.1107/s1744309109002887	2009
	Structure of a membrane-embedded prenyltransferase homologous to UBIAD1.	Huang H, Levin EJ, Liu S, Bai Y, Lockless SW, Zhou M.	PLoS Biol	10.1371/journal.pbio.1001911	2014
Metabolism	A Structurally Novel Lipoyl Synthase in the Hyperthermophilic Archaeon Thermococcus kodakarensis.	Jin JQ, Hachisuka SI, Sato T, Fujiwara T, Atomi H.	Appl Environ Microbiol	10.1128/aem.01359-20	2020
Metabolism	[NiFe]-hydrogenases are constitutively expressed in an enriched Methanobacterium sp. population during electromethanogenesis.	Perona-Vico E, Blasco-Gomez R, Colprim J, Puig S, Baneras L.	PLoS One	10.1371/journal.pone.0215029	2019
Metabolism	The TK0271 Protein Activates Transcription of Aromatic Amino Acid Biosynthesis Genes in the Hyperthermophilic Archaeon Thermococcus kodakarensis.	Yamamoto Y, Kanai T, Kaneseki T, Atomi H.	mBio	10.1128/mbio.01213-19	2019
	Phylogeny and Taxonomy of Archaea: A Comparison of the Whole-Genome-Based CVTree Approach with 16S rRNA Sequence Analysis.	Zuo G, Xu Z, Hao B.	Life (Basel)	10.3390/life5010949	2015
Metabolism	An intertwined evolutionary history of methanogenic archaea and sulfate reduction.	Susanti D, Mukhopadhyay B.	PLoS One	10.1371/journal.pone.0045313	2012
Metabolism	Reverse Methanogenesis and Respiration in Methanotrophic Archaea.	Timmers PH, Welte CU, Koehorst JJ, Plugge CM, Jetten MS, Stams AJ.	Archaea	10.1155/2017/1654237	2017
Enzymology	Purification, crystallization and preliminary crystallographic analysis of the non-Pfam protein AF1514 from Archeoglobus fulgidus DSM 4304.	Bahti P, Chen S, Li Y, Shaw N, Zhang X, Zhang M, Cheng C, Song G, Yin J, Zhang H, Che D, Abbas A, Xu H, Wang BC, Liu ZJ.	Acta Crystallogr Sect F Struct Biol Cryst Commun	10.1107/s1744309107068649	2008
Genetics	Structural and functional insight into the universal stress protein family.	Tkaczuk KL, A Shumilin I, Chruszcz M, Evdokimova E, Savchenko A, Minor W.	Evol Appl	10.1111/eva.12057	2013
	Minigene as a Novel Regulatory Element in Toxin-Antitoxin Systems.	Kedzierska B, Potrykus K.	Int J Mol Sci	10.3390/ijms222413389	2021
	Similar gene estimates from circular and linear standards in quantitative PCR analyses using the prokaryotic 16S rRNA gene as a model.	Oldham AL, Duncan KE.	PLoS One	10.1371/journal.pone.0051931	2012
Genetics	Phyletic Distribution and Lineage-Specific Domain Architectures of Archaeal Two-Component Signal Transduction Systems.	Galperin MY, Makarova KS, Wolf YI, Koonin EV.	J Bacteriol	10.1128/jb.00681-17	2018
Metabolism	A Phosphofructokinase Homolog from Pyrobaculum calidifontis Displays Kinase Activity towards Pyrimidine Nucleosides and Ribose 1-Phosphate.	Aziz I, Bibi T, Rashid N, Aono R, Atomi H, Akhtar M.	J Bacteriol	10.1128/jb.00284-18	2018
Genetics	An electroporation-free method based on Red recombineering for markerless deletion and genomic replacement in the Escherichia coli DH1 genome.	Wei Y, Deng P, Mohsin A, Yang Y, Zhou H, Guo M, Fang H.	PLoS One	10.1371/journal.pone.0186891	2017
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Enzymology	Kinetic and structural characterization of DmpI from Helicobacter pylori and Archaeoglobus fulgidus, two 4-oxalocrotonate tautomerase family members.	Almrud JJ, Dasgupta R, Czerwinski RM, Kern AD, Hackert ML, Whitman CP.	Bioorg Chem	10.1016/j.bioorg.2010.07.002	2010
Metabolism	Rapid discovery and evolution of orthogonal aminoacyl-tRNA synthetase-tRNA pairs.	Cervettini D, Tang S, Fried SD, Willis JCW, Funke LFH, Colwell LJ, Chin JW.	Nat Biotechnol	10.1038/s41587-020-0479-2	2020
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Metabolism	Structure of an amide bond forming F(420):gamma-glutamyl ligase from Archaeoglobus fulgidus -- a member of a new family of non-ribosomal peptide synthases.	Nocek B, Evdokimova E, Proudfoot M, Kudritska M, Grochowski LL, White RH, Savchenko A, Yakunin AF, Edwards A, Joachimiak A.	J Mol Biol	10.1016/j.jmb.2007.06.063	2007
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	Interaction between hydrogenase maturation factors HypA and HypB is required for [NiFe]-hydrogenase maturation.	Chan KH, Lee KM, Wong KB.	PLoS One	10.1371/journal.pone.0032592	2012
Enzymology	Crystal structures of an archaeal oligosaccharyltransferase provide insights into the catalytic cycle of N-linked protein glycosylation.	Matsumoto S, Shimada A, Nyirenda J, Igura M, Kawano Y, Kohda D.	Proc Natl Acad Sci U S A	10.1073/pnas.1309777110	2013
Metabolism	Comparative Analysis of Archaeal Lipid-linked Oligosaccharides That Serve as Oligosaccharide Donors for Asn Glycosylation.	Taguchi Y, Fujinami D, Kohda D.	J Biol Chem	10.1074/jbc.m115.713156	2016
Enzymology	Structural and Kinetic Characterization of Hyperthermophilic NADH-Dependent Persulfide Reductase from Archaeoglobus fulgidus.	Shabdar S, Anaclet B, Castineiras AG, Desir N, Choe N, Crane EJ 3rd, Sazinsky MH	Archaea	10.1155/2021/8817136	2021
Enzymology	The serine, threonine, and/or tyrosine-specific protein kinases and protein phosphatases of prokaryotic organisms: a family portrait.	Shi L, Potts M, Kennelly PJ	FEMS Microbiol Rev	10.1111/j.1574-6976.1998.tb00369.x	1998
Enzymology	Spectroscopic studies on APS reductase isolated from the hyperthermophilic sulfate-reducing archaebacterium Archaeglobus fulgidus.	Lampreia J, Fauque G, Speich N, Dahl C, Moura I, Truper HG, Moura JJ	Biochem Biophys Res Commun	10.1016/s0006-291x(05)81424-x	1991
Metabolism	5'-Methylbenzimidazolyl-cobamides are the corrinoids from some sulfate-reducing and sulfur-metabolizing bacteria.	Krautler B, Kohler HP, Stupperich E	Eur J Biochem	10.1111/j.1432-1033.1988.tb14303.x	1988
Enzymology	Vitamin contents of archaebacteria.	Noll KM, Barber TS	J Bacteriol	10.1128/jb.170.9.4315-4321.1988	1988
	Rate and Extent of Growth of a Model Extremophile, Archaeoglobus fulgidus, Under High Hydrostatic Pressures.	Oliver GC, Cario A, Rogers KL	Front Microbiol	10.3389/fmicb.2020.01023	2020
Metabolism	Assessment of the Carbon Monoxide Metabolism of the Hyperthermophilic Sulfate-Reducing Archaeon Archaeoglobus fulgidus VC-16 by Comparative Transcriptome Analyses.	Hocking WP, Roalkvam I, Magnussen C, Stokke R, Steen IH	Archaea	10.1155/2015/235384	2015
Metabolism	Improved enantioselectivity of thermostable esterase from Archaeoglobus fulgidus toward (S)-ketoprofen ethyl ester by directed evolution and characterization of mutant esterases.	Kim J, Kim S, Yoon S, Hong E, Ryu Y	Appl Microbiol Biotechnol	10.1007/s00253-015-6422-7	2015
Metabolism	Anaerobic oxidation of long-chain n-alkanes by the hyperthermophilic sulfate-reducing archaeon, Archaeoglobus fulgidus.	Khelifi N, Amin Ali O, Roche P, Grossi V, Brochier-Armanet C, Valette O, Ollivier B, Dolla A, Hirschler-Rea A	ISME J	10.1038/ismej.2014.58	2014
Metabolism	Phenylalanine catabolism in Archaeoglobus fulgidus VC-16.	Parthasarathy A, Kahnt J, Chowdhury NP, Buckel W	Arch Microbiol	10.1007/s00203-013-0925-3	2013
Proteome	The crystal structure of the AF2331 protein from Archaeoglobus fulgidus DSM 4304 forms an unusual interdigitated dimer with a new type of alpha + beta fold.	Wang S, Kirillova O, Chruszcz M, Gront D, Zimmerman MD, Cymborowski MT, Shumilin IA, Skarina T, Gorodichtchenskaia E, Savchenko A, Edwards AM, Minor W	Protein Sci	10.1002/pro.251	2009
Metabolism	Temperature effect on the sulfur isotope fractionation during sulfate reduction by two strains of the hyperthermophilic Archaeoglobus fulgidus.	Mitchell K, Heyer A, Canfield DE, Hoek J, Habicht KS	Environ Microbiol	10.1111/j.1462-2920.2009.02002.x	2009
Phylogeny	Nucleotide triplet based molecular phylogeny of class I and class II aminoacyl t-RNA synthetase in three domain of life process: bacteria, archaea, and eukarya.	Mondal UK, Das B, Ghosh TC, Sen A, Bothra AK	J Biomol Struct Dyn	10.1080/07391102.2008.10507247	2008
Enzymology	Cloning and characterization of thermostable esterase from Archaeoglobus fulgidus.	Kim SB, Lee W, Ryu YW	J Microbiol	10.1007/s12275-007-0185-5	2008
Enzymology	Heat shock response of Archaeoglobus fulgidus.	Rohlin L, Trent JD, Salmon K, Kim U, Gunsalus RP, Liao JC	J Bacteriol	10.1128/JB.187.17.6046-6057.2005	2005
Enzymology	The putative lipase, AF1763, from Archaeoglobus fulgidusis is a carboxylesterase with a very high pH optimum.	Rusnak M, Nieveler J, Schmid RD, Petri R	Biotechnol Lett	10.1007/s10529-005-5621-1	2005
Cultivation	A variant of the hyperthermophile Archaeoglobus fulgidus adapted to grow at high salinity.	Goncalves LG, Huber R, da Costa MS, Santos H	FEMS Microbiol Lett	10.1111/j.1574-6968.2003.tb11523.x	2003
Enzymology	Dissimilatory ATP sulfurylase from the hyperthermophilic sulfate reducer Archaeoglobus fulgidus belongs to the group of homo-oligomeric ATP sulfurylases.	Sperling D, Kappler U, Wynen A, Dahl C, Truper HG	FEMS Microbiol Lett	10.1111/j.1574-6968.1998.tb13007.x	1998
Phylogeny	A possible biochemical missing link among archaebacteria.	Achenbach-Richter L, Stetter KO, Woese CR	Nature	10.1038/327348a0	1987
	Natrarchaeobiusversutus sp. nov. and Natrarchaeobius oligotrophus sp. nov., chitinotrophic natronoarchaea from hypersaline soda lakes, and functional genome analysis of the Natrarchaeobius species	Tulenkov A, Elcheninov A, Sorokin D.	Front Microbiol		2025

References

#1648	Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 4304
#20215	Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 )
#66792	Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) .
#66794	Antje Chang, Lisa Jeske, Sandra Ulbrich, Julia Hofmann, Julia Koblitz, Ida Schomburg, Meina Neumann-Schaal, Dieter Jahn, Dietmar Schomburg: BRENDA, the ELIXIR core data resource in 2021: new developments and updates. Nucleic Acids Res. 49: D498 - D508 2020 ( DOI 10.1093/nar/gkaa1025 , PubMed 33211880 )
#67770	Japan Collection of Microorganism (JCM) ; Curators of the JCM;
#69479	João F Matias Rodrigues, Janko Tackmann,Gregor Rot, Thomas SB Schmidt, Lukas Malfertheiner, Mihai Danaila,Marija Dmitrijeva, Daniela Gaio, Nicolas Näpflin and Christian von Mering. University of Zurich.: MicrobeAtlas 1.0 beta .
#125438	Julia Koblitz, Lorenz Christian Reimer, Rüdiger Pukall, Jörg Overmann: Predicting bacterial phenotypic traits through improved machine learning using high-quality, curated datasets. 2024 ( DOI 10.1101/2024.08.12.607695 )
#125439	Philipp Münch, René Mreches, Martin Binder, Hüseyin Anil Gündüz, Xiao-Yin To, Alice McHardy: deepG: Deep Learning for Genome Sequence Data. R package version 0.3.1 .
#126262	A. Lissin, I. Schober, J. F. Witte, H. Lüken, A. Podstawka, J. Koblitz, B. Bunk, P. Dawyndt, P. Vandamme, P. de Vos, J. Overmann, L. C. Reimer: StrainInfo—the central database for linked microbial strain identifiers. ( DOI 10.1093/database/baaf059 )

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Archaeoglobus fulgidus (DSM 4304, ATCC 49558, JCM 9628)

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