Gardnerella vaginalis 594 is an anaerobe, thermophilic, Gram-variable bacterium that forms round colonies and was isolated from vaginal secretions.

colony-forming
Gram-variable
anaerobe
thermophilic
16S sequence
Bacteria
genome sequence

Information on the name and the taxonomic classification. Name and taxonomic classification

	Last LPSN update	14-12-2023 (DD-MM-YYYY)
	Domain	"Bacteria"
	Phylum	*Actinomycetota*
	Class	*Actinomycetes*
	Order	*Bifidobacteriales*
	Family	*Bifidobacteriaceae*
	Genus	*Gardnerella*
	Species	**Gardnerella vaginalis**
	Full Scientific Name (LPSN)	Gardnerella vaginalis (Gardner and Dukes 1955) Greenwood and Pickett 1980

	Synonym	"Corynebacterium* vaginale"*
	Synonym	Haemophilus vaginalis

Information on morphological and physiological properties Morphology

[Ref.: #22917]	Gram stain	variable
[Ref.: #123778]	Gram stain	negative
[Ref.: #69480]	Gram stain	positive Confidence in %99.999

[Ref.: #22917]	Cell length	1.5 µm

[Ref.: #22917]	Cell width	0.5 µm

[Ref.: #123778]	Cell shape	rod-shaped

[Ref.: #123778]	Motility	no
[Ref.: #69480]	Motility	no Confidence in %92.218

[Ref.: #123778]	Hemolysis ability	1

[Ref.: #22917]	Colony color	opaque
[Ref.: #22917]	Colony shape	round

Information on culture and growth conditions Culture and growth conditions

[Ref.: #1884]

Culture medium

COLUMBIA BLOOD MEDIUM (DSMZ Medium 693)

[Ref.: #1884]

Culture medium growth

[Ref.: #1884]

Culture medium link

Medium recipe at MediaDive

[Ref.: #1884]

Culture medium composition

expand / minimize

[Ref.: #1884]

Culture medium

BHI MEDIUM (DSMZ Medium 215)

[Ref.: #1884]

Culture medium growth

[Ref.: #1884]

Culture medium link

Medium recipe at MediaDive

[Ref.: #1884]

Culture medium composition

expand / minimize

[Ref.: #36208]

Culture medium

MEDIUM 252 - for Gardnerella and Propionibacterium lymphophilum

[Ref.: #36208]

Culture medium growth

[Ref.: #36208]

Culture medium composition

expand / minimize

[Ref.: #123778]

Culture medium

CIP Medium 252

[Ref.: #123778]

Culture medium growth

[Ref.: #123778]

Culture medium link

Medium recipe provided by DSMZ

[Ref.: #123778]

Culture medium

CIP Medium 26

[Ref.: #123778]

Culture medium growth

[Ref.: #123778]

Culture medium link

Medium recipe provided by DSMZ

	Kind of temperature		Temperature
[Ref.: #1884]		growth	37 °C
[Ref.: #22917]		maximum	42 °C
[Ref.: #22917]		minimum	25 °C
[Ref.: #36208]		growth	37 °C
[Ref.: #44687]		growth	37 °C
[Ref.: #67770]		growth	37 °C
[Ref.: #123778]		growth	30-41 °C
[Ref.: #123778]	no	growth	10 °C
[Ref.: #123778]	no	growth	15 °C
[Ref.: #123778]	no	growth	25 °C
[Ref.: #123778]	no	growth	45 °C

[Ref.: #1884]	Temperature range	mesophilic
[Ref.: #22917]	Temperature range	thermophilic
[Ref.: #22917]	Temperature range	mesophilic
[Ref.: #36208]	Temperature range	mesophilic
[Ref.: #44687]	Temperature range	mesophilic
[Ref.: #67770]	Temperature range	mesophilic
[Ref.: #123778]	Temperature range	psychrophilic
[Ref.: #123778]	Temperature range	mesophilic
[Ref.: #123778]	Temperature range	thermophilic

	pH	Kind of pH		pH
[Ref.: #22917]			minimum	4.5
[Ref.: #22917]			optimum	6 - 6.5

Information on physiology and metabolism Physiology and metabolism

[Ref.: #1884]	Oxygen tolerance	anaerobe
[Ref.: #1884]	Oxygen tolerance	microaerophile
[Ref.: #44687]	Oxygen tolerance	anaerobe
[Ref.: #44687]	Oxygen tolerance	microaerophile
[Ref.: #123778]	Oxygen tolerance	facultative anaerobe
[Ref.: #69480]	Oxygen tolerance	anaerobe Confidence in %99.999

[Ref.: #69481]	Ability of spore formation	no Confidence in %100
[Ref.: #69480]	Ability of spore formation	no Confidence in %99.997

[Ref.: #22917]

Name of produced compound

Acetic acid

	Salt	Tested relation		Salt conc.
[Ref.: #123778]	NaCl		growth	0	%
[Ref.: #123778]	NaCl	no	growth	2	%
[Ref.: #123778]	NaCl	no	growth	4	%
[Ref.: #123778]	NaCl	no	growth	6	%
[Ref.: #123778]	NaCl	no	growth	8	%
[Ref.: #123778]	NaCl	no	growth	10	%

	Metabolite	Utilization activity	Kind of utilization tested
[Ref.: #68381]	alpha-cyclodextrin ChEBI	-	builds acid from	* from API rID32STR
[Ref.: #22917]	arbutin ChEBI	-	builds acid from
[Ref.: #68368]	arginine ChEBI	-	hydrolysis	* from API 20E, API rID32A, API rID32STR
[Ref.: #22917]	biotin ChEBI	+	required for growth
[Ref.: #22917]	cellobiose ChEBI	-	builds acid from
[Ref.: #123778]	citrate ChEBI	-	carbon source
[Ref.: #68368]	citrate ChEBI	-	assimilation	* from API 20E
[Ref.: #68376]	D-arabitol ChEBI	-	builds acid from	* from API LIST, API rID32STR
[Ref.: #68377]	D-fructose ChEBI	+	builds acid from	* from API NH
[Ref.: #68377]	D-glucose ChEBI	+	builds acid from	* from API NH
[Ref.: #68368]	D-glucose ChEBI	-	fermentation	* from API 20E
[Ref.: #68381]	D-mannitol ChEBI	-	builds acid from	* from API rID32STR
[Ref.: #68376]	D-ribose ChEBI	-	builds acid from	* from API LIST, API rID32STR
[Ref.: #68376]	D-tagatose ChEBI	-	builds acid from	* from API LIST, API rID32STR
[Ref.: #68376]	D-xylose ChEBI	-	builds acid from	* from API LIST
[Ref.: #22917]	dextrin ChEBI	+	builds acid from
[Ref.: #123778]	esculin ChEBI	-	hydrolysis
[Ref.: #68376]	esculin ChEBI	-	hydrolysis	* from API LIST
[Ref.: #22917]	folate ChEBI	+	required for growth
[Ref.: #22917]	fructose ChEBI	+	builds acid from
[Ref.: #22917]	galactose ChEBI	+	builds acid from
[Ref.: #68368]	gelatin ChEBI	-	hydrolysis	* from API 20E
[Ref.: #22917]	glucose ChEBI	+	builds acid from
[Ref.: #68376]	glucose 1-phosphate ChEBI	-	builds acid from	* from API LIST
[Ref.: #68381]	glycogen ChEBI	-	builds acid from	* from API rID32STR
[Ref.: #123778]	hippurate ChEBI	+	hydrolysis
[Ref.: #68381]	L-arabinose ChEBI	-	builds acid from	* from API rID32STR
[Ref.: #68376]	L-rhamnose ChEBI	-	builds acid from	* from API LIST
[Ref.: #68368]	L-rhamnose ChEBI	-	fermentation	* from API 20E
[Ref.: #22917]	lactose ChEBI	+	fermentation
[Ref.: #68381]	lactose ChEBI	-	builds acid from	* from API rID32STR
[Ref.: #68368]	lysine ChEBI	-	degradation	* from API 20E
[Ref.: #22917]	maltose ChEBI	+	builds acid from
[Ref.: #68377]	maltose ChEBI	+	builds acid from	* from API NH
[Ref.: #68381]	maltose ChEBI	-	builds acid from	* from API rID32STR
[Ref.: #22917]	mannitol ChEBI	-	builds acid from
[Ref.: #22917]	mannose ChEBI	+	builds acid from
[Ref.: #68381]	melezitose ChEBI	-	builds acid from	* from API rID32STR
[Ref.: #68381]	melibiose ChEBI	-	builds acid from	* from API rID32STR
[Ref.: #68368]	melibiose ChEBI	-	fermentation	* from API 20E
[Ref.: #68376]	methyl alpha-D-glucopyranoside ChEBI	-	builds acid from	* from API LIST
[Ref.: #68381]	methyl beta-D-glucopyranoside ChEBI	-	builds acid from	* from API rID32STR
[Ref.: #22917]	myo-inositol ChEBI	-	builds acid from
[Ref.: #68368]	myo-inositol ChEBI	-	fermentation	* from API 20E
[Ref.: #22917]	nicotinamide ChEBI	+	required for growth
[Ref.: #22917]	nitrate ChEBI	-	reduction
[Ref.: #123778]	nitrate ChEBI	-	reduction
[Ref.: #123778]	nitrate ChEBI	+	respiration
[Ref.: #68368]	nitrate ChEBI	-	reduction	* from API 20E, API rID32A
[Ref.: #123778]	nitrite ChEBI	-	reduction
[Ref.: #68368]	ornithine ChEBI	-	degradation	* from API 20E, API NH
[Ref.: #68381]	pullulan ChEBI	-	builds acid from	* from API rID32STR
[Ref.: #68381]	raffinose ChEBI	-	builds acid from	* from API rID32STR
[Ref.: #22917]	rhamnose ChEBI	-	builds acid from
[Ref.: #22917]	riboflavin ChEBI	+	required for growth
[Ref.: #22917]	ribose ChEBI	+	builds acid from
[Ref.: #22917]	sorbitol ChEBI	-	builds acid from
[Ref.: #68381]	sorbitol ChEBI	-	builds acid from	* from API rID32STR
[Ref.: #68368]	sorbitol ChEBI	-	fermentation	* from API 20E
[Ref.: #22917]	starch ChEBI	+	builds acid from
[Ref.: #22917]	sucrose ChEBI	+	fermentation
[Ref.: #68377]	sucrose ChEBI	-	builds acid from	* from API NH, API rID32STR
[Ref.: #68368]	sucrose ChEBI	-	fermentation	* from API 20E
[Ref.: #22917]	thiamine ChEBI	+	required for growth
[Ref.: #68381]	trehalose ChEBI	-	builds acid from	* from API rID32STR
[Ref.: #123778]	tributyrin ChEBI	+	hydrolysis
[Ref.: #68368]	tryptophan ChEBI	-	energy source	* from API 20E, API NH, API rID32A
[Ref.: #68368]	urea ChEBI	-	hydrolysis	* from API 20E, API NH, API rID32A, API rID32STR
[Ref.: #22917]	xylose ChEBI	+	fermentation
	Only first 10 entries are displayed. Click here to see all.

	Antibiotica	Metabolite	Antibiotic sensitivity	Antibiotic resistance
[Ref.: #123778]		0129 (2,4-Diamino-6,7-di-iso-propylpteridine phosphate)	yes	no

	Metabolite	Production
[Ref.: #22917]	acetate ChEBI	yes
[Ref.: #22917]	indole ChEBI	no
[Ref.: #123778]	indole ChEBI	no
[Ref.: #68368]	acetoin ChEBI	no	* from API 20E, API rID32STR
[Ref.: #68368]	dinitrogen ChEBI	no	* from API 20E
[Ref.: #68368]	hydrogen sulfide ChEBI	no	* from API 20E
[Ref.: #68377]	indole ChEBI	no	* from API NH, API 20E, API rID32A
[Ref.: #68368]	nitrite ChEBI	no	* from API 20E

	Metabolite	Voges-Proskauer-test	Methylred-test	Indole test
[Ref.: #123778]	acetoin ChEBI	-
[Ref.: #123778]	glucose ChEBI		+
[Ref.: #68381]	acetoin ChEBI	-			* from API rID32STR, API 20E
[Ref.: #68380]	indole ChEBI			-	* from API rID32A, API NH, API 20E

	Enzyme	Enzyme activity	EC number
[Ref.: #68382]	acid phosphatase	+	3.1.3.2	* from API zym
[Ref.: #68381]	Alanyl-Phenylalanyl-Proline arylamidase	+		* from API rID32STR
[Ref.: #123778]	alcohol dehydrogenase	-	1.1.1.1
[Ref.: #68381]	alkaline phosphatase	+	3.1.3.1	* from API rID32STR
[Ref.: #68382]	alkaline phosphatase	-	3.1.3.1	* from API zym, API rID32A, API NH
[Ref.: #68380]	alpha-arabinosidase	-	3.2.1.55	* from API rID32A
[Ref.: #68382]	alpha-chymotrypsin	-	3.4.21.1	* from API zym
[Ref.: #68382]	alpha-fucosidase	-	3.2.1.51	* from API zym
[Ref.: #68382]	alpha-galactosidase	-	3.2.1.22	* from API zym, API rID32STR, API rID32A
[Ref.: #68382]	alpha-glucosidase	+	3.2.1.20	* from API zym
[Ref.: #68382]	alpha-mannosidase	-	3.2.1.24	* from API zym, API LIST
[Ref.: #123778]	amylase	-
[Ref.: #68381]	arginine dihydrolase	-	3.5.3.6	* from API rID32STR, API rID32A, API 20E
[Ref.: #123778]	beta-galactosidase	+	3.2.1.23
[Ref.: #68382]	beta-galactosidase	+	3.2.1.23	* from API zym, API rID32STR
[Ref.: #68377]	beta-galactosidase	-	3.2.1.23	* from API NH, API 20E
[Ref.: #68380]	beta-Galactosidase 6-phosphate	-		* from API rID32A
[Ref.: #68382]	beta-glucosidase	-	3.2.1.21	* from API zym, API rID32STR, API rID32A, API LIST
[Ref.: #68382]	beta-glucuronidase	-	3.2.1.31	* from API zym, API rID32STR, API rID32A
[Ref.: #68377]	beta-lactamase	-	3.5.2.6	* from API NH
[Ref.: #68381]	beta-mannosidase	-	3.2.1.25	* from API rID32STR
[Ref.: #123778]	caseinase	-	3.4.21.50
[Ref.: #22917]	catalase	-	1.11.1.6
[Ref.: #123778]	catalase	-	1.11.1.6
[Ref.: #68382]	cystine arylamidase	-	3.4.11.3	* from API zym
[Ref.: #22917]	cytochrome oxidase	-	1.9.3.1
[Ref.: #123778]	DNase	-
[Ref.: #123778]	gamma-glutamyltransferase	-	2.3.2.2
[Ref.: #68377]	gamma-glutamyltransferase	-	2.3.2.2	* from API NH
[Ref.: #123778]	gelatinase	-
[Ref.: #68368]	gelatinase	-		* from API 20E
[Ref.: #68380]	glutamyl-glutamate arylamidase	-		* from API rID32A
[Ref.: #68381]	glycyl tryptophan arylamidase	-		* from API rID32STR
[Ref.: #123778]	lecithinase	-
[Ref.: #68382]	leucine arylamidase	+	3.4.11.1	* from API zym
[Ref.: #123778]	lipase	-
[Ref.: #68377]	lipase	-		* from API NH
[Ref.: #68382]	lipase (C 14)	-		* from API zym
[Ref.: #123778]	lysine decarboxylase	-	4.1.1.18
[Ref.: #68368]	lysine decarboxylase	-	4.1.1.18	* from API 20E
[Ref.: #68382]	N-acetyl-beta-glucosaminidase	-	3.2.1.52	* from API zym, API rID32STR, API rID32A
[Ref.: #68382]	naphthol-AS-BI-phosphohydrolase	-		* from API zym
[Ref.: #123778]	ornithine decarboxylase	-	4.1.1.17
[Ref.: #68377]	ornithine decarboxylase	-	4.1.1.17	* from API NH, API 20E
[Ref.: #123778]	oxidase	-
[Ref.: #123778]	phenylalanine ammonia-lyase	-	4.3.1.24
[Ref.: #68380]	proline-arylamidase	+	3.4.11.5	* from API rID32A, API NH
[Ref.: #123778]	protease	-
[Ref.: #68381]	pyrrolidonyl arylamidase	-	3.4.19.3	* from API rID32STR, API rID32A
[Ref.: #68382]	trypsin	-	3.4.21.4	* from API zym
[Ref.: #123778]	tryptophan deaminase	-
[Ref.: #68380]	tryptophan deaminase	-	4.1.99.1	* from API rID32A, API NH, API 20E
[Ref.: #123778]	tween esterase	+
[Ref.: #22917]	urease	-	3.5.1.5
[Ref.: #123778]	urease	-	3.5.1.5
[Ref.: #68381]	urease	-	3.5.1.5	* from API rID32STR, API rID32A, API NH, API 20E
[Ref.: #68382]	valine arylamidase	-		* from API zym
	Only first 10 entries are displayed. Click here to see all.